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Autophagy and cancer

http://libcat.nshealth.ca/permalink/provcat32578
Hong-Gang Wang, editor. Springer , c2013.
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This book covers the latest advances in the field of autophagy and cancer from the basics of the molecular machinery for autophagy induction and regulation up to current areas of interest, including modulation of autophagy and drug discovery for cancer prevention and treatment. The reader will be initially introduced to the historical context of autophagy, followed by a summary of the key players in autophagy, a discussion on the origin of autophagosomes, and an overview of signal transduction …
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Other Authors
Wang, Hong-Gang
Responsibility
Hong-Gang Wang, editor
Place of Publication
New York, NY
Publisher
Springer
Date Published
c2013
Physical Description
1 online resource (xi, 261 p. : 33 ill., 29 ill. in color)
Series Title
Current cancer research
ISBN
9781461465614
Subjects (MeSH)
Autophagy
Neoplasms
Subjects (LCSH)
Cytology
Human physiology
Medicine
Oncology
Abstract
This book covers the latest advances in the field of autophagy and cancer from the basics of the molecular machinery for autophagy induction and regulation up to current areas of interest, including modulation of autophagy and drug discovery for cancer prevention and treatment. The reader will be initially introduced to the historical context of autophagy, followed by a summary of the key players in autophagy, a discussion on the origin of autophagosomes, and an overview of signal transduction regulation of autophagy. The next chapters deal with the complex relationship between autophagy and tumorigenesis through in-depth discussions of how autophagy influences cell survival, apoptosis, inflammation, immunity, tumor microenvironment, metabolic stress, DNA damage, and genomic instability. The remaining chapters discuss how autophagy affects cancer cell response to therapy and how to best modulate autophagy for therapeutic benefit - what to target and how to target. We hope that this monograph will be an invaluable reference source for professionals, students, postdoctoral fellows, and senior scientists working in the fields of autophagy and cancer.
Contents
Preface -- Historical Overview of Autophagy -- The Core Molecular Machinery of Autophagosome Formation -- The origin of autophagosomes: The beginning of an end -- Signal Transduction Regulation of Autophagy -- Role of Autophagy in Tumorigenesis -- Selective autophagy and cancer -- Oncogenes and tumor suppressor genes in autophagy -- Autophagy and Immunity -- Autophagy and the Tumor Microenvironment -- Autophagy and Cancer Therapy -- The Crosstalk between Apoptosis & Autophagy -- Autophagy and Cancer Drug Discovery -- Index.
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e-Book
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Berne & Levy physiology

http://libcat.nshealth.ca/permalink/provcat31558
editors, Bruce M. Koeppen, Bruce A. Stanton. (7th ed.) Elsevier , c2018.
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Berne, Robert M
Koeppen, Bruce M
Stanton, Bruce A
Responsibility
editors, Bruce M. Koeppen, Bruce A. Stanton
Edition
7th ed.
Alternate Title
Berne and Levy physiology
Physiology
Place of Publication
Philadelphia, PA
Publisher
Elsevier
Date Published
c2018
Physical Description
1 online resource
ISBN
9780323393942
Subjects (MeSH)
Physiological Phenomena
Subjects (LCSH)
Human physiology
Physiological Phenomena
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Fundamentals of Biomechanics : Equilibrium, Motion, and Deformation

http://libcat.nshealth.ca/permalink/provcat30935
Nihat Özkaya ... [et al.]. (3rd ed.) Springer , c2012.
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Biomechanics applies the principles and rigor of engineering to the mechanical properties of living systems. This book integrates the classic fields of mechanics--statics, dynamics, and strength of materials--using examples from biology and medicine. Fundamentals of Biomechanics is excellent for teaching either undergraduates in biomedical engineering programs or health care professionals studying biomechanics at the graduate level. Extensively revised from a successful second edition, the boo…
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Özkaya, Nihat
Responsibility
Nihat Özkaya ... [et al.]
Edition
3rd ed.
Place of Publication
New York, NY
Publisher
Springer
Date Published
c2012
Physical Description
1 online resource (xvii, 275 p. : 526 ill.)
ISBN
9781461411505
Subjects (MeSH)
Bioengineering
Biomechanical Phenomena
Kinetics
Subjects (LCSH)
Human physiology
Orthopedics
Rehabilitation
Sports medicine
Abstract
Biomechanics applies the principles and rigor of engineering to the mechanical properties of living systems. This book integrates the classic fields of mechanics--statics, dynamics, and strength of materials--using examples from biology and medicine. Fundamentals of Biomechanics is excellent for teaching either undergraduates in biomedical engineering programs or health care professionals studying biomechanics at the graduate level. Extensively revised from a successful second edition, the book features a wealth of clear illustrations, numerous worked examples, and many problem sets. The book provides the quantitative perspective missing from more descriptive texts, without requiring an advanced background in mathematics. It will be welcomed for use in courses such as biomechanics and orthopedics, rehabilitation and industrial engineering, and occupational or sports medicine.
Contents
Introduction -- Force Vector -- Moment And Torque Vectors -- Statics: Systems in Equilibrium -- Applications of Statics to Biomechanics -- Introduction to Dynamics -- Linear Kinematics -- Linear Kinetics -- Angular Kinematics -- Angular Kinetics -- Impulse and Momentum -- Introduction to Deformable Body Mechanics -- Stress and Strain -- Multiaxial Deformations and Stress Analyses -- Mechanical Properties of Biological Tissues -- Appendix A: Plane Geometry -- Appendix B: Vector Algebra -- Appendix C: Calculus.
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e-Book
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Guyton and Hall textbook of medical physiology

http://libcat.nshealth.ca/permalink/provcat31567
Hall, John E. (12th ed.) Saunders Elsevier , c2011.
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The 12th edition of Guyton and Hall Textbook of Medical Physiology continues its long tradition as one of the world's favorite physiology textbooks. The success of this book is due to its description of complex physiologic principles in language that is easy to read and understand. Now with an improved color art program, thorough updates reflecting today's medicine and science, and online accessibility at studentconsult.com, this textbook is an excellent source for mastering essential human phy…
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Author
Hall, John E
Other Authors
Guyton, Arthur C
Edition
12th ed.
Alternate Title
Textbook of medical physiology
Place of Publication
Philadelphia, PA
Publisher
Saunders Elsevier
Date Published
c2011
Physical Description
1 online resource
ISBN
9781437726749 (electronic bk.)
Subjects (MeSH)
Physiological Phenomena
Subjects (LCSH)
Human physiology
Physiological Phenomena
Physiological processes
Physiology
Physiology, Pathological
Notes
Rev. ed. of: Textbook of medical physiology. 11th ed. c2006.
Abstract
The 12th edition of Guyton and Hall Textbook of Medical Physiology continues its long tradition as one of the world's favorite physiology textbooks. The success of this book is due to its description of complex physiologic principles in language that is easy to read and understand. Now with an improved color art program, thorough updates reflecting today's medicine and science, and online accessibility at studentconsult.com, this textbook is an excellent source for mastering essential human physiology knowledge. Learn and remember vital concepts easily thanks to short, easy-to-read, masterfully edited chapters and a user-friendly full-color design. See core concepts applied to real-life situations with clinical vignettes throughout the text
Contents
Functional organization of the human body and control of the "internal environment" -- The cell and its functions -- Genetic control of protein synthesis, cell function, and cell reproduction -- Transport of substances through cell membranes -- Membrane potentials and action protentials -- Contraction of skeletal muscle -- Excitation of skeletal muscle: neuromuscular transmission and excitation-contraction coupling -- Excitation and contraction of smooth muscle -- Cardiac muscle; the heart as a pump and function of the heart valves -- Rhythmical excitation of the heart -- The normal electrocardiogram -- Electrocardiographic interpretation of cardiac muscle and coronary blood flow abnormalities: vectorial analysis -- Cardiac arrhythmias and their electrocardiographic interpretations -- Overview of the circulation; biophysics of pressure, flow, and resistance -- Vascular distensibility and functions of the arterial and venous systems -- The microcirculation and lymphatic system: capillary fluid exchange, interstitial fluid, and lymph flow -- Local and humoral control of tissue blood flow -- Nervous regulation of the circulation, and rapid control of arterial pressure -- Role of the kidneys in long-term control of arterial pressure and in hypertension: the integrated system for arterial pressure regulation -- Cardiac output, venous return, and their regulation -- Muscle blood flow and cardiac output during exercise; the coronary circulation and ischemic heart disease -- Cardiac failure -- Heart valves and heart sounds; valvular and congenital heart defects -- Circulatory shock and its treatment -- The body fluid compartments: extracellular and intracellular fluids; edema -- Urine formation by the kidneys: I. Glomerular filtration, renal blood flow, and their control -- Urine formation by the kidneys: II. tubular reabsorption and secretion -- Urine concentration and dilution; regulation of extracellular fluid osmolarity and sodium concentration -- Renal regulation of potassium, calcium, phosphate, and magnesium; integration of renal mechanisms for control of blood volume and extracellular fluid volume -- Acid-base regulation -- Diuretics, kidney diseases -- Red blood cells, anemia, and polycythemia -- Resistance of the body to infection: I. leukocytes, granulocytes, the monocyte-macrophage system, and inflammation -- Resistance of the body to infection: II. immunity and allergy innate immunity -- Blood types; transfusion; tissue and organ transplantation -- Hemostasis and blood coagulation -- Pulmonary ventilation -- Pulmonary circulation, pulmonary edema, pleural fluid -- Physical principles of gas exchange; diffusion of oxygen and carbon dioxide through the respiratory membrane -- Transport of oxygen and carbon dioxide in blood and tissue fluids -- Regulation of respiration -- Respiratory insufficiency-pathophysiology, diagnosis, oxygen therapy -- Aviation, high-altitude, and space physiology -- Physiology of deep-sea diving and other hyperbaric conditions -- Organization of the nervous system, basic functions of synapses, and neurotransmitters -- Sensory receptors, neuronal circuits for processing information -- Somatic sensations: I. general organization, the tactile and position senses -- Somatic sensations: II. pain, headache, and thermal sensations -- The eye: I. optics of vision -- The eye: II. receptor and neural function of the retina -- The eye: III. central neurophysiology of vision -- The sense of hearing -- The chemical senses-taste and smell -- Motor functions of the spinal cord; the cord reflexes -- Cortical and brain stem control of motor function -- Contributions of the cerebellum and basal ganglia to overall motor control -- Cerebral cortex, intellectual functions of the brain, learning, and memory -- Behavioral and motivational mechanisms of the brain-the limbic system and the hypothalamus -- States of brain activity-sleep, brain waves, epilepsy, psychoses -- The autonomic nervous system and the adrenal medulla -- Cerebral blood flow, cerebrospinal fluid, and brain metabolism -- General principles of gastrointestinal function-motility, nervous control, and blood circulation -- Propulsion and mixing of food in the alimentary tract -- Secretory functions of the alimentary tract -- Digestion and absorption in the gastrointestinal tract -- Physiology and gastrointestinal disorders -- Metabolism of carbohydrates, and formation of adenosine triphosphate -- Lipid metabolmis -- Protein metabolism -- The liver as an organ -- Dietary balances; regulation of feeding; obesity and starvation; vitamins and minerals -- Energetics and metabolic rate -- Body temperature regulation, and fever -- Introduction to endocrinology -- Pituitary hormones and their control by the hypothalamus -- Thyroid metabolic hormones -- Adrenocortical hormones -- Insulin, glucagon, and diabetes mellitus -- Parathyroid hormone, calcitonin, calcium and phosphate metabolism, vitamin D, bone, and teeth -- Reproductive and hormonal functions of the male (and function of the pineal gland) -- Female physiology before pregnancy and female hormones -- Pregnancy and lactation -- Fetal and neonatal physiology -- Sports physiology.
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Human anatomy & physiology / Robert Carola, John P. Harley, Charles R. Noback.

http://libcat.nshealth.ca/permalink/provcat14473
Carola, Robert. (2nd edition) New York : McGraw-Hill, c1992.
Call Number
QS 4 C37 1992
Location
Aberdeen Hospital
Call Number
QS 4 C37 1992
Author
Carola, Robert
Other Authors
Harley, John P.
Noback, Charles R. (Charles Robert), 1916-2009
Edition
2nd edition
Publisher
New York : McGraw-Hill, c1992.
Physical Description
xl, 978, [101] p. : ill. (some col.) ; 29 cm.
ISBN
0070109648
Other Subjects
Human anatomy
Human physiology
Format
Book
Location
Aberdeen Hospital
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JIMD reports : case and research reports, 2012/4

http://libcat.nshealth.ca/permalink/provcat32512
Johannes Zschocke, K. Michael Gibson, editors-in-chief ; Garry Brown, Eva Morava, editors ; Verena Peters, managing editor. Springer ; SSIEM , c2013.
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JIMD Reports publishes case and short research reports in the area of inherited metabolic disorders. Case reports highlight some unusual or previously unrecorded feature relevant to the disorder, or serve as an important reminder of clinical or biochemical features of a Mendelian disorder.
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Other Authors
Brown, Garry
Gibson, K. Michael
Morava, Eva
Peters, Verena
Society for the Study of Inborn Errors of Metabolism
Zschocke, Johannes
Responsibility
Johannes Zschocke, K. Michael Gibson, editors-in-chief ; Garry Brown, Eva Morava, editors ; Verena Peters, managing editor
Alternate Title
Journal of inherited metabolic disorders reports
Place of Publication
Berlin
Publisher
Springer ; SSIEM
Date Published
c2013
Physical Description
1 online resource (vii, 128 p.)
Series Vol.
v. 7
Series Title
JIMD reports
ISBN
9783642324420 (e-ISBN) 9783642324413
ISSN
2192-8312 (electronic)
Subjects (MeSH)
Metabolism, Inborn Errors
Subjects (LCSH)
Human genetics
Human physiology
Metabolic diseases
Pediatrics
Abstract
JIMD Reports publishes case and short research reports in the area of inherited metabolic disorders. Case reports highlight some unusual or previously unrecorded feature relevant to the disorder, or serve as an important reminder of clinical or biochemical features of a Mendelian disorder.
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e-Book
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JIMD reports : case and research reports, 2012/5

http://libcat.nshealth.ca/permalink/provcat32515
Johannes Zschocke, K. Michael Gibson, editors-in-chief ; Garry Brown, Eva Morava, editors ; Verena Peters, managing editor. Springer ; SSIEM , c2013.
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JIMD Reports publishes case and short research reports in the area of inherited metabolic disorders. Case reports highlight some unusual or previously unrecorded feature relevant to the disorder, or serve as an important reminder of clinical or biochemical features of a Mendelian disorder.
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Other Authors
Brown, Garry
Gibson, K. Michael
Morava, Eva
Peters, Verena
Society for the Study of Inborn Errors of Metabolism
Zschocke, Johannes
Responsibility
Johannes Zschocke, K. Michael Gibson, editors-in-chief ; Garry Brown, Eva Morava, editors ; Verena Peters, managing editor
Alternate Title
Journal of inherited metabolic disorders reports
Place of Publication
Berlin
Publisher
Springer ; SSIEM
Date Published
c2013
Physical Description
1 online resource (vii, 152 p.)
Series Vol.
v. 8
Series Title
JIMD reports
ISBN
9783642334320
9783642334337 (e-ISBN)
ISSN
2192-8312 (electronic)
Subjects (MeSH)
Metabolism, Inborn Errors
Subjects (LCSH)
Human genetics
Human physiology
Metabolic diseases
Pediatrics
Abstract
JIMD Reports publishes case and short research reports in the area of inherited metabolic disorders. Case reports highlight some unusual or previously unrecorded feature relevant to the disorder, or serve as an important reminder of clinical or biochemical features of a Mendelian disorder.
Format
e-Book
Location
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JIMD reports : case and research reports, 2012/6

http://libcat.nshealth.ca/permalink/provcat32517
Johannes Zschocke, K. Michael Gibson, editors-in-chief ; Garry Brown, Eva Morava, editors ; Verena Peters, managing editor. Springer ; SSIEM , c2013.
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JIMD Reports publishes case and short research reports in the area of inherited metabolic disorders. Case reports highlight some unusual or previously unrecorded feature relevant to the disorder, or serve as an important reminder of clinical or biochemical features of a Mendelian disorder.
Available Online
View e-Book
Other Authors
Brown, Garry
Gibson, K. Michael
Morava, Eva
Peters, Verena
Society for the Study of Inborn Errors of Metabolism
Zschocke, Johannes
Responsibility
Johannes Zschocke, K. Michael Gibson, editors-in-chief ; Garry Brown, Eva Morava, editors ; Verena Peters, managing editor
Alternate Title
Journal of inherited metabolic disorders reports
Place of Publication
Berlin
Publisher
Springer ; SSIEM
Date Published
c2013
Physical Description
1 online resource (vi, 142 p.)
Series Vol.
v. 9
Series Title
JIMD reports
ISBN
9783642355172
9783642355189 (e-ISBN)
ISSN
2192-8312 (electronic)
Subjects (MeSH)
Metabolism, Inborn Errors
Subjects (LCSH)
Human genetics
Human physiology
Metabolic diseases
Pediatrics
Abstract
JIMD Reports publishes case and short research reports in the area of inherited metabolic disorders. Case reports highlight some unusual or previously unrecorded feature relevant to the disorder, or serve as an important reminder of clinical or biochemical features of a Mendelian disorder.
Format
e-Book
Location
Online
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Medical physiology

http://libcat.nshealth.ca/permalink/provcat31867
[edited by] Walter F. Boron, Emile L. Boulpaep. (3rd ed.) Elsevier , c2017.
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For a comprehensive understanding of human physiology — from molecules to systems —turn to the latest edition of Medical Physiology. This updated textbook is known for its unparalleled depth of information, equipping students with a solid foundation for a future in medicine and healthcare, and providing clinical and research professionals with a reliable go-to reference. Complex concepts are presented in a clear, concise, and logically organized format to further facilitate understanding and r…
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Other Authors
Boron, Walter F
Boulpaep, Emile L
Responsibility
[edited by] Walter F. Boron, Emile L. Boulpaep
Edition
3rd ed.
Place of Publication
Philadelphia, PA
Publisher
Elsevier
Date Published
c2017
Physical Description
1 online resource (1297 p)
ISBN
9781455743773 (electronic bk.)
Subjects (MeSH)
Cell Physiological Phenomena
Physiological Phenomena
Subjects (LCSH)
Cell Physiological Phenomena
Genomics
Human physiology
Physiology
Abstract
For a comprehensive understanding of human physiology — from molecules to systems —turn to the latest edition of Medical Physiology. This updated textbook is known for its unparalleled depth of information, equipping students with a solid foundation for a future in medicine and healthcare, and providing clinical and research professionals with a reliable go-to reference. Complex concepts are presented in a clear, concise, and logically organized format to further facilitate understanding and retention.
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The Netter collection of medical illustrations. Vol. 6, Musculoskeletal system. Part 3, Biology and systemic diseases

http://libcat.nshealth.ca/permalink/provcat32238
illustrations by Frank H. Netter and Carlos A.G. Machado. (2nd ed.) Elsevier Saunders , 2011.
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Other Authors
Machado, Carlos A.G
Netter, Frank Henry
Responsibility
illustrations by Frank H. Netter and Carlos A.G. Machado
Edition
2nd ed.
Alternate Title
Biology and systemic diseases
Musculoskeletal system
Place of Publication
Philadelphia
Publisher
Elsevier Saunders
Date Published
2011
Physical Description
1 online resource
ISBN
9781455726608 (electronic bk.)
Subjects (MeSH)
Anatomy - Atlases
Subjects (LCSH)
Human anatomy
Human physiology
Medical illustration
Medical Illustration - Atlases
Pathology
Notes
Previously known as "Ciba collection of medical illustrations" and "Netter green book collection".
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Novel Insights in the Neurochemistry and Function of Pulmonary Sensory Receptors

http://libcat.nshealth.ca/permalink/provcat31134
Inge Brouns ... [et al.]. Springer , c2012.
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Airway sensory nerve terminals are tailored to detect changes in the physical and chemical environment, thereby supplying local pulmonary information to the central nervous system. Since most intrapulmonary nerve terminals arise from fibres travelling in the vagal nerve, the classification of sensory airway receptors' is largely based on their action potential characteristics, electrophysiologically registered from the vagal nerve. However, the architecture of airways and lungs makes it nearly…
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Author
Brouns, Inge
Responsibility
Inge Brouns ... [et al.]
Place of Publication
Berlin, Heidelberg
Publisher
Springer
Date Published
c2012
Physical Description
1 online resource (xii, 118 p. : 23 ill., 21 ill. in color)
Series Vol.
211
Series Title
Advances in anatomy, embryology and cell biology
ISBN
9783642227721
Subjects (MeSH)
Immunohistochemistry
Lung - innervation
Muscle, Smooth - innervation
Sensory Receptor Cells - physiology
Subjects (LCSH)
Human physiology
Neurochemistry
Pneumonology
Abstract
Airway sensory nerve terminals are tailored to detect changes in the physical and chemical environment, thereby supplying local pulmonary information to the central nervous system. Since most intrapulmonary nerve terminals arise from fibres travelling in the vagal nerve, the classification of sensory airway receptors' is largely based on their action potential characteristics, electrophysiologically registered from the vagal nerve. However, the architecture of airways and lungs makes it nearly impossible to functionally locate the exact nerve terminals that are responsible for the transduction of a particular intrapulmonary stimulus. In this monograph we focus on three sensory receptor end organs in lungs that are currently morphologically well-characterised: smooth muscle-associated airway receptors (SMARs), neuroepithelial bodies (NEBs) and visceral pleura receptors (VPRs). Unravelling the main functional morphological and neurochemical characteristics of these sensory receptors using advanced immunohistochemistry and confocal microscopy has already allowed us to draw important conclusions about their potential function(s). The current development of ex vivo lung models for the selective identification of SMARs, NEBs and VPRs using vital staining will certainly facilitate direct physiological studies of these morphologically well-characterised airway receptors, since these models allow direct live studies of their functional properties.
Contents
Sensory Nerve Terminals in Intrapulmonary Airways and Lungs -- Electrophysiologically Identified Airway Receptors: Main Characteristics -- Morphology and Location of Electrophysiologically Identified Sensory Airway Receptors -- The Neurochemical Coding of Airway Afferents -- Morphologically Identified Sensory Receptor End-Organs in the Airways, Lungs and Visceral Pleura -- In Situ Functional Imaging of Sensory Receptors in Lung Models -- Concluding Remarks and Future Prospects.
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e-Book
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editor Linda S. Constanzo. (6th ed.) Elsevier , c2018.
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Renowned physiology instructor Dr. Linda Costanzo’s friendly, logical, easy-to-follow writing style makes Physiology, 6th Edition ideal for coursework and USMLE preparation. Well-designed figures and tables provide handy visuals for procedures or physiologic equations, and step-by-step explanations clarify challenging concepts. This full-color, manageably-sized text offers a comprehensive and consistent overview of core physiologic concepts at the organ system and cellular levels, making compl…
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Other Authors
Costanzo, Linda S
Responsibility
editor Linda S. Constanzo
Edition
6th ed.
Place of Publication
Philadelphia, PA
Publisher
Elsevier
Date Published
c2018
Physical Description
1 online resource, 516 p.
ISBN
9780323478816
Subjects (MeSH)
Physiological Phenomena
Physiology
Subjects (LCSH)
Human physiology
Physiology
Abstract
Renowned physiology instructor Dr. Linda Costanzo’s friendly, logical, easy-to-follow writing style makes Physiology, 6th Edition ideal for coursework and USMLE preparation. Well-designed figures and tables provide handy visuals for procedures or physiologic equations, and step-by-step explanations clarify challenging concepts. This full-color, manageably-sized text offers a comprehensive and consistent overview of core physiologic concepts at the organ system and cellular levels, making complex principles easy to understand.
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Principles of Renal Physiology

http://libcat.nshealth.ca/permalink/provcat30984
Christopher J. Lote. (5th ed.) Springer , c2012.
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A good knowledge of renal physiology is essential to the understanding of many disease states. The purpose of the book is to set out the principles of renal physiology and normal renal function. Now in its 30th year of continuous publication, this new edition offers a logical progression through renal physiology and pathophysiology. In addition, the anatomy, physiology, pharmacology and pathology of the kidney are covered, making it highly suitable for system based courses. This 5th edition h…
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Author
Lote, Christopher J
Responsibility
Christopher J. Lote
Edition
5th ed.
Place of Publication
New York, NY
Publisher
Springer
Date Published
c2012
Physical Description
1 online resource (xv, 204 p. : 78 ill., 31 ill. in color)
ISBN
9781461437857
Subjects (MeSH)
Kidney - physiology
Renal Circulation - physiology
Subjects (LCSH)
Human physiology
Nephrology
Abstract
A good knowledge of renal physiology is essential to the understanding of many disease states. The purpose of the book is to set out the principles of renal physiology and normal renal function. Now in its 30th year of continuous publication, this new edition offers a logical progression through renal physiology and pathophysiology. In addition, the anatomy, physiology, pharmacology and pathology of the kidney are covered, making it highly suitable for system based courses. This 5th edition has been extensively revised and features a wealth of new and widely accepted information about kidney function. This includes our understanding of the role of the glycocalyx and structural proteins in glomerular filtration; details of tubular transport, tight junctions and paracellular transport; and an update of the loops of Henle functioning. Principles of Renal Physiology, 5th Edition is a concise and easily readable text ideal for undergraduate medical and medical science students.
Contents
The Body Fluids -- Essential Anatomy of the Kidney -- Glomerular Filtration -- Tubular Transport -- The Proximal Tubule -- The Loop of Henle, Distal Tubule and Collecting Duct -- Renal Blood Flow and Glomerular Filtration Rate -- Regulation of Body Fluid Osmolality -- Regulation of Body Fluid Volume -- Renal Regulation of Body Fluid pH -- Renal Control of Body Fluid Potassium Content -- Renal Regulation of Body Calcium, Magnesium and Phosphate -- Summary of the Principle Reabsorptive and Secretory Processes in the Nephron Segments -- Disease Conditions Which Alter Renal Sodium and Water Reabsorption -- Use of Diuretics.
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e-Book
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Translational Vascular Medicine : Pathogenesis, Diagnosis, and Treatment

http://libcat.nshealth.ca/permalink/provcat30829
David Abraham ... [et al.], editors. Springer , c2012.
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Modern medicine is increasingly focused on integrating the results of basic scientific research and clinical research, "translational medicine" to provide improved patient care. This collaborative approach which is a "two way street" has proven very useful in various fields in cardiovascular medicine. Translational Vascular Medicine: Pathogenesis, Diagnosis, and Treatment provides extensive information on new and exciting advances in such topics as surgery and non-pharmacological treatments fo…
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Other Authors
Abraham, David
Responsibility
David Abraham ... [et al.], editors
Place of Publication
London
Publisher
Springer
Date Published
c2012
Physical Description
1 online resource (xiv, 266 p. : 54 ill., 28 ill. in color)
ISBN
9780857299208
Subjects (MeSH)
Translational Medical Research
Subjects (LCSH)
Cardiology
Gene expression
Human physiology
Abstract
Modern medicine is increasingly focused on integrating the results of basic scientific research and clinical research, "translational medicine" to provide improved patient care. This collaborative approach which is a "two way street" has proven very useful in various fields in cardiovascular medicine. Translational Vascular Medicine: Pathogenesis, Diagnosis, and Treatment provides extensive information on new and exciting advances in such topics as surgery and non-pharmacological treatments for atherosclerotic disease of the aorta, pulmonary arterial hypertension, cytoprotective mechanisms in the vasculature, and the "Broken Heart Syndrome". The Editors and their expert panel of contributors have explored the bi-directional and integrated approaches of translational cardiovascular medicine, linking basic science to patient care. This book is a highly useful method to understand these complex topics and provides considerable insight into important areas of translational cardiovascular medicine and key bibliographies for the reader.
Contents
Section I. Hot Topics in Vascular Biology -- 1. Pericytes: Adaptable vascular progenitors -- 2. Benefits and risks of manipulating the HIF hydroxylase pathway in ischaemic heart disease -- 3. Cytoprotective mechanisms in the vasculature -- 4. Notch signalling in vascular development -- Section II. Novel Molecular Mediators Regulating Cardiovascular System -- 5. The therapeutic potential of dimethylarginine dimethylaminohydrolase-mediated regulation of nitric oxide synthesis. -- 6. Potassium channels regulating the electrical activity of the heart -- 7. Free radicals oxidant stress and cardiovascular disease -- Section III. Clinical Aspects of Cardiovascular Disease -- 8. The Takotsubo (Broken Heart Syndrome) -- 9. Lymphatic endothelium in health and disease -- 10. Importance of subtype selectivity for endothelin receptor antagonists in the human vasculature -- 11. Non-pharmacological treatment of Peripheral Vascular Disease -- 12. Surgical Approaches to Abdominal Aortic Aneurysm Repair -- Section IV. Clinical and Translational Aspects of Pulmonary Vascular Disease -- 13. Understanding the pathobiology of pulmonary vascular disease -- 14. Inflammation in pulmonary arterial hypertension -- 15. Endothelin Receptor Antagonists in Cardiovascular Medicine: Challenges and Opportunities.
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e-Book
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