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1644 records – page 1 of 165.

Intraepithelial neoplasia

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Maode Lai, editor. Higher Education Press , c2009.
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Intraepithelial neoplasia (IEN) are some kind of preinvasive lesions. The definition and identification of intraepithelial neoplasia is exceedingly important for early diagnosis and prevention of malignancy. This book introduces for the first time the concept of intraepithelial neoplasia for the entire body in detail and the diagnostic applications of intraepithelial neoplasia in many organs and systems – including the respiratory and digestive systems, pancreas, bile duct, breast, prostate, ur…
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Other Authors
Lai, Maode
Responsibility
Maode Lai, editor
Place of Publication
Beijing, China
Publisher
Higher Education Press
Date Published
c2009
Physical Description
1 online resource (xiii, 364 p. : ill.)
ISBN
9783540854524 (print ed.)
9783540854531
Subjects (MeSH)
Carcinoma in situ - diagnosis
Carcinoma in situ - therapy
Precancerous conditions - diagnosis
Precancerous conditions - therapy
Abstract
Intraepithelial neoplasia (IEN) are some kind of preinvasive lesions. The definition and identification of intraepithelial neoplasia is exceedingly important for early diagnosis and prevention of malignancy. This book introduces for the first time the concept of intraepithelial neoplasia for the entire body in detail and the diagnostic applications of intraepithelial neoplasia in many organs and systems – including the respiratory and digestive systems, pancreas, bile duct, breast, prostate, urinary system, female genital system and the skin. The book features a large number of original figures – 450 – from Chinese patients with detailed descriptions. The book can serve as a diagnostic reference and as a research guide to preinvasive lesions for pathologists, oncologists and scientists. In addition, it will be able to help medical and pathology students improve their understanding of early neoplasia. Prof. Dr. med. Maode Lai is one of the most widely respected pathologists in China. He is vice president of Zhejiang University and Chairman-elect of the Chinese Society of Pathology. His major work is focused on molecular pathology of tumors, especially colorectal cancer.
Contents
Intraepithelial Neoplasia of the Respiratory Tract -- Intraepithelial Neoplasia of the Digestive Tract -- Intraepithelial Neoplasia of Pancreas, Biliary Tract and Gallbladder -- Intraepithelial Neoplasia of the Breast -- Prostatic Intraepithelial Neoplasia -- Urinary Intraepithelial Neoplasia (Intra-urothelial Neoplasia) -- Intraepithelial Neoplasia of the Female Reproductive Tract -- Intraepidermal Neoplasia of Skin --
Format
e-Book
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The Surgeon in Medieval English Literature

http://libcat.nshealth.ca/permalink/provcat40518
by Jeremy J. Citrome. Palgrave Macmillan , c2006.
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Jeremy Citrome employs the language of contemporary psychoanalysis to explain how surgical metaphors became an important tool of ecclesiastical power in the wake of the Fourth Lateran Council of 1215. Pastoral, theological, recreational, and medical writings are among the texts discussed in this wide-ranging study.
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Author
Citrome, Jeremy J
Responsibility
by Jeremy J. Citrome
Place of Publication
New York
Publisher
Palgrave Macmillan
Date Published
c2006
Physical Description
1 online resource (xi, 191 p.)
Series Title
New Middle Ages
ISBN
9781137096814
9781349734597 (print ed.)
Subjects (MeSH)
Christianity
General surgery - history
History, Medieval
Medicine in Literature
Other Subjects
; Medicine & Public Health
Classical and Antique Literature
History of Medicine
History of Medieval Europe
Medieval Literature
United Kingdom
Abstract
Jeremy Citrome employs the language of contemporary psychoanalysis to explain how surgical metaphors became an important tool of ecclesiastical power in the wake of the Fourth Lateran Council of 1215. Pastoral, theological, recreational, and medical writings are among the texts discussed in this wide-ranging study.
Contents
Part I. Surgery and Metaphor -- 1. Surgery as Damnation in Cleanness -- 2. Salvation and The Siege of Jerusalem -- Part II. Surgery and Embodiment -- 3. The Priest: John Audelay's Wounds of Sin -- 4. The Surgeon: Surgery, Chivalry, and Sin in the Practica of ]ohn Arderne.
Format
e-Book
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Establishing Medical Reality : Essays In The Metaphysics And Epistemology Of Biomedical Science

http://libcat.nshealth.ca/permalink/provcat40572
edited by Harold Kincaid and Jennifer McKitrick. Springer , c2007.
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Medicine raises numerous philosophical issues. Most discussed have been debates in bioethics. Yet contemporary medicine is also a rich source of controversies and examples that raise important issues in philosophy of science, philosophy of biology, and metaphysics. This volume approaches the philosophy of medicine from the broad naturalist perspective that holds that philosophy must be continuous with, constrained by, and relevant to empirical results of the natural and social sciences and that…
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Other Authors
Kincaid, Harold, 1952-
McKitrick, Jennifer
Responsibility
edited by Harold Kincaid and Jennifer McKitrick
Place of Publication
Dordrecht
Publisher
Springer
Date Published
c2007
Physical Description
1 online resource (vii, 236 p.)
Series Vol.
v. 90
Series Title
Philosophy and medicine
ISBN
9781402052156 (print ed.)
9781402052163
Subjects (MeSH)
Bioethical issues
Metaphysics
Philosophy, Medical
Other Subjects
; Medicine & Public Health
Medicine/Public Health, general
Metaphysics
Philosophy of Medicine
Philosophy of Science
Philosophy of the Social Sciences
Abstract
Medicine raises numerous philosophical issues. Most discussed have been debates in bioethics. Yet contemporary medicine is also a rich source of controversies and examples that raise important issues in philosophy of science, philosophy of biology, and metaphysics. This volume approaches the philosophy of medicine from the broad naturalist perspective that holds that philosophy must be continuous with, constrained by, and relevant to empirical results of the natural and social sciences and that believes that the history, sociology, politics, and ethics of science provide relevant information for philosophical analysis. One traditional topic covered by several of the contributions is the nature of disease, but the approach is largely from the philosophy of science rather than traditional linguistic analysis. The complex interplay of epistemological and sociological factors in producing evidence in medicine is discussed by chapters on collective medical discussion making, experimental medicine, "genetic" diseases, mental illness, and race and gender categories. The upshot is a volume that ties medicine to contemporary issues in philosophy of science and metaphysics like no other. "An excellent collection of essays in the philosophy of medicine. Whereas most philosophical work about medicine has been concerned with medical ethics, this volume focuses more on key questions in epistemology and metaphysics, although many of these are also relevant to ethical issues. Some of the chapters are among the best I have read in the philosophy of medicine on their respective topics." Professor Paul Thagard, Philosophy Department, University of Waterloo, Ontario, Canada.
Contents
Introduction -- Normality, Disease and Enhancement -- Holistic Theories of Health as Applicable to Non-Human Living Beings -- Disease and the Concept of Supervenience -- Decision and Discovery in Defining "Disease" -- Race and Scientific Reduction -- Towards an Adequate Account of Genetic Disease -- Why Disease Persists: An Evolutionary Nosology -- Creating Mental Illness in Non-Disordered Community Populations -- Gender Identity Disorder -- Clinical Trials as Nomological Machines: Implications for Evidence-Based Medicine -- The Social Epistemology of NIH Consensus Conferences -- Maternal Agency and the Immunological Paradox of Pregnancy -- Violence and Public Health: Exploring the Relationship Between Biological Perspectives on Violent Behavior and Public Health Approaches to Violence Prevention -- Taking Equipoise Seriously: The Failure of Clinical or Community Equipoise to Resolve the Ethical Dilemmas in Randomized Clinical Trials.
Format
e-Book
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The Histone Code and Beyond : New Approaches to Cancer Therapy

http://libcat.nshealth.ca/permalink/provcat40551
S.L. Berger, O. Nakanishi, B. Haendler, editors. Springer Berlin Heidelberg , c2006.
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Methylation of DNA at cytosine residues as well as post-translational modifications of histones, including phosphorylation, acetylation, methylation and ubiquitylation, contribute to the epigenetic information carried by chromatin. These changes play an important role in the regulation of gene expression by modulating the access of regulatory factors to the DNA. The use of a combination of biochemical, genetic and structural approaches has allowed demonstration of the role of chromatin structur…
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Other Authors
Berger, S. L
Haendler, B
Nakanishi, O
Responsibility
S.L. Berger, O. Nakanishi, B. Haendler, editors
Place of Publication
Berlin, Heidelberg
Publisher
Springer Berlin Heidelberg
Date Published
c2006
Physical Description
1 online resource (xiv, 215 p.)
Series Vol.
57
Series Title
Ernst Schering Research Foundation workshop
ISBN
9783540278573 (print ed.)
9783540376330
ISSN
0947-6075
Subjects (MeSH)
Histones
Other Subjects
; Life Sciences
Biochemistry, general
Cell Biology
Oncology
Abstract
Methylation of DNA at cytosine residues as well as post-translational modifications of histones, including phosphorylation, acetylation, methylation and ubiquitylation, contribute to the epigenetic information carried by chromatin. These changes play an important role in the regulation of gene expression by modulating the access of regulatory factors to the DNA. The use of a combination of biochemical, genetic and structural approaches has allowed demonstration of the role of chromatin structure in transcriptional control. The structure of nucleosomes has been elucidated and enzymes involved in DNA or histone modifications have been extensively characterized. Since deregulation of epigenetic marks has been reported in many cancers, a better understanding of the underlying molecular mechanisms bears the promise that new drug targets may soon be found. The newest developments in this quickly developing field are presented in this book.
Contents
The Role of Histone Modifications in Epigenetic Transitions During Normal and Perturbed Development -- Nucleosome Structure and Function -- The Role of Snf2-Related Proteins in Cancer -- Imitation Switch Complexes -- How Is Epigenetic Information on Chromatin Inherited After DNA Replication? -- Polycomb Silencing Mechanisms and Genomic Programming -- CpG Island Methylation and Histone Modifications: Biology and Clinical Significance -- Histone Post-Translational Modifications Regulate Transcription and Silent Chromatin in Saccharomyces Cerevisiae -- Histone Acetylation-Mediated Chromatin Compaction During Mouse Spermatogenesis -- Role of Ubiquitin-Like Proteins in Transcriptional Regulation -- Interplay of the SUMO and MAP Kinase Pathways.
Format
e-Book
Publication Type
Congresses
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HIV/AIDS in U.S. Communities of Color

http://libcat.nshealth.ca/permalink/provcat40940
Valerie Stone, Bisola Ojikutu, M. Keith Rawlings, Kimberly Y. Smith, editors. Springer , c2009.
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More people in communities of color are contracting, living with, and being treated for HIV/AIDS than ever before. In 2005, 71% of new AIDS cases were diagnosed in people of color. Though the number of racial and ethnic minority HIV/AIDS cases continues to grow, the health care community has been unable to adequately meet the unique medical needs of these populations. African-American, Latino/Latina, and other patients of color are less likely to seek medical care, have sufficient access to the…
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Other Authors
Ojikutu, Bisola
Rawlings, M. Keith
Smith, Kimberly Y
Stone, Valerie
Responsibility
Valerie Stone, Bisola Ojikutu, M. Keith Rawlings, Kimberly Y. Smith, editors
Place of Publication
New York, NY
Publisher
Springer
Date Published
c2009
Physical Description
1 online resource (x, 309 p. : 4 illus.)
ISBN
9780387981512 (print ed.)
9780387981529
Subjects (MeSH)
Acquired immunodeficiency syndrome - ethnology
HIV Infections - ethnology
Minority Groups
Minority Health
Social conditions
United States - epidemiology
Other Subjects
; Medicine & Public Health
Health Promotion and Disease Prevention
Infectious Diseases
Abstract
More people in communities of color are contracting, living with, and being treated for HIV/AIDS than ever before. In 2005, 71% of new AIDS cases were diagnosed in people of color. Though the number of racial and ethnic minority HIV/AIDS cases continues to grow, the health care community has been unable to adequately meet the unique medical needs of these populations. African-American, Latino/Latina, and other patients of color are less likely to seek medical care, have sufficient access to the health care system, or receive the drugs they need for as long as they need them. HIV/AIDS in U.S. Communities of Color is an outstanding resource for any professional working with these underserved populations. Comprehensive chapters cover issues as far-reaching as: anti-retroviral therapy; dermatologic manifestations and co-morbidities of the disease in patients of color; unique risks to women and MSMs of color; participation of minority cases in HIV research; and substance abuse and mental health issues. Complied by world experts in HIV/AIDS, this book analyzes the main causes of treatment failure and promotes respect for individual and cultural values, teaching readers to provide responsive, patient-centered care and devise preventive strategies for communities of color.
Contents
The Epidemiology, Prevention and Control of HIV/AIDS among African Americans -- HIV/AIDS and Latino Populations in the US: Epidemiology, Prevention and Barriers to Care and Treatment -- Antiretroviral Therapy and Communities of Color -- Overcoming Challenges to Successful Treatment Outcomes in Minority Patients with HIV/AIDS -- Access to Culturally Competent Care for Patients Living with HIV/AIDS -- Women of Color and HIV/AIDS: Epidemiology, Clinical Aspects, and Management -- Management of Pregnancy in HIV-Infected Women and Prevention of Mother-to-Child Transmission -- The Dermatological Manifestations of HIV Infection in Ethnic Skin -- Comorbidities in Black Patients with HIV/AIDS -- Men Who Have Sex With Men of Color in the Age of AIDS: The Sociocultural Contexts of Stigma, Marginalization, and Structural Inequalities -- HIV Prevention and Heterosexual African American Women -- Substance Abuse, HIV and Mental Health Issues: Prevention and Treatment Changes -- African Americans and HIV Research -- The Impact of HIV Policies and Politics on Communities of Color -- Moving Toward a Unified Global HIV/AIDS Agenda: Communities of Color in Crisis.
Format
e-Book
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Atlas of Clinical Neurology

http://libcat.nshealth.ca/permalink/provcat30486
Rosenberg, Roger N. (3rd ed.) Current Medicine Group , c2009.
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Location
Online
The newly revised, comprehensive, four-color Atlas of Clinical Neurology is extensively updated with reference to current literature. The new third edition organizes the highest-quality images from the field of clinical neurology, including clinical syndromes, for neurologists and clinicians. The atlas highlights the enormous strides being made in the biologic understanding of neurologic disease, covering developmental and genetic diseases, neuroendocrine disorders, critical care neurology, cer…
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Author
Rosenberg, Roger N
Edition
3rd ed.
Place of Publication
Philadelphia, PA
Publisher
Current Medicine Group
Date Published
c2009
Physical Description
1 online resource (602 p.)
ISBN
9781573403597
Subjects (MeSH)
Nervous system diseases - atlases
Subjects (LCSH)
Neurology
Abstract
The newly revised, comprehensive, four-color Atlas of Clinical Neurology is extensively updated with reference to current literature. The new third edition organizes the highest-quality images from the field of clinical neurology, including clinical syndromes, for neurologists and clinicians. The atlas highlights the enormous strides being made in the biologic understanding of neurologic disease, covering developmental and genetic diseases, neuroendocrine disorders, critical care neurology, cerebrovascular disease, dementias, behavioral neurology, neuro-oncology, movement disorders, epilepsy, neuromuscular diseases, infectious diseases, neuroimmunology, neurotoxic disorders, and headache. This indispensable collection contains over 1300 images including algorithms, tables, charts, and schematic drawings.
Contents
Developmental Diseases of the Nervous System -- Genetic Diseases of the Nervous System -- Neuroendocrine Disorders -- Coma and Intensive Care Neurology -- Cerebrovascular Disease -- Dementias -- Behavioral Neurology -- Neuro-oncology -- Movement Disorders -- The Epilepsies -- Neuromuscular Disease -- Infectious Diseases of the Nervous System -- Neuroimmunology -- Neurotoxic Disorders -- Headache.
Format
e-Book
Location
Online
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Gender and Recovery from Coronary Artery Bypass Surgery : A Psychological Perspective

http://libcat.nshealth.ca/permalink/provcat40955
Friederike Kendel. Steinkopff , c2009.
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The number of coronary artery bypass graft (CABG) operations has increased continually over the past decade. To date, roughly one-third of these are performed on women. Despite the tremendous progress made in cardiovascular surgery, not all patients profit equally from it, and the mortality rate of women still exceeds that of men by a factor of two. Studies conducted to investigate this marked gender difference have yielded conflicting results. In particular, adjustment for clinical risk factor…
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Author
Kendel, Friederike
Responsibility
Friederike Kendel
Place of Publication
Darmstadt
Publisher
Steinkopff
Date Published
c2009
Physical Description
1 online resource (viii, 98 p. : 11 illus., 8 illus. in color)
Series Vol.
7
Series Title
Fortschritte der Herz-, Thorax- und Gefäßchirurgie
ISBN
9783798518551 (print ed.)
9783798518568
Subjects (MeSH)
Coronary Artery Bypass - psychology
Coronary Artery Bypass - rehabilitation
Sex factors
Other Subjects
; Medicine & Public Health
Cardiology
Abstract
The number of coronary artery bypass graft (CABG) operations has increased continually over the past decade. To date, roughly one-third of these are performed on women. Despite the tremendous progress made in cardiovascular surgery, not all patients profit equally from it, and the mortality rate of women still exceeds that of men by a factor of two. Studies conducted to investigate this marked gender difference have yielded conflicting results. In particular, adjustment for clinical risk factors seemed to diminish the difference, but could not fully explain it. Therefore psychosocial parameters, in particular depression and psychosocial stress, have gained increasing attention as predictors for both mortality and quality of life after CABG operation. Gender differences in these variables have long been observed in patients undergoing CABG: female patients are on average older, more often depressive and more often living alone than male patients. This book presents the very first German study to focus on these gender differences. By describing the gender-specific influence of psychological and clinical variables on the recovery process, this work fills an important gap in cardiovascular research. Its approach is interdisciplinary in the best sense. The study underlines the importance of psychosocial variables for both mortality and quality of life in the context of CABG. Thus, it may be seen as a basis for a better understanding and treatment of CABG patients.
Contents
1. Introduction -- 1.1 Gender Differences in Mortality After CABG -- 1.2 Gender Aspects of Risk Factors -- 1.3 Outcome Measures -- 2. Hypotheses -- 2.1 Gender Differences in Risk Factors and Outcomes -- 2.2 Moderator Hypotheses -- 2.3 Mediator Hypotheses -- 3. Method -- 3.1 Participants -- 3.2 Measurements -- 3.3 General Statistical Procedures -- 3.4 Sample -- 4. Results -- 4.1 Predictors of Mortality and Physical Functioning Based on Preoperative Data -- 4.2 Predictors of Well-Being Based on Longitudinal Data -- 4.3 Predictive Relationship Between Physical Functioning and Depression -- 5. Discussion -- 5.1 Gender Differences in Outcome -- 5.2 Gender Aspects in Recovery -- 5.3 Is Depression Predictive for Physical Functioning? -- 5.4 Limitations -- 5.5 Clinical Implications -- 5.6 Conclusion -- 6. Summary -- 7. Zusammenfassung -- 8. References.
Format
e-Book
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Cancer Proteomics : From Bench to Bedside

http://libcat.nshealth.ca/permalink/provcat40631
edited by Sayed S. Daoud. Humana Press , c2008.
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Over the past 20 years or so, there have been tremendous advances in our understanding of how normal cells transform to cancer and the importance of signaling pathways in cancer initiation and progression. Therefore, proteomics technologies must be improved for more global analysis of protein content of cells, tissues and body fluids as well as the posttranslational modifications to allow for proper detections and validation. In Cancer Proteomics, the authors collectively provide the current st…
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Other Authors
Daoud, Sayed S
Responsibility
edited by Sayed S. Daoud
Place of Publication
Totowa, NJ
Publisher
Humana Press
Date Published
c2008
Physical Description
1 online resource (xii, 264 p. : 5 illus. in color)
Series Title
Cancer drug discovery and development
ISBN
9781588298584 (print ed.)
9781597451697
Subjects (MeSH)
Antineoplastic agents
Biomarkers, Tumor
Neoplasms
Proteomics - methods
Other Subjects
; Biomedicine
Cancer Research
Oncology
Proteomics
Abstract
Over the past 20 years or so, there have been tremendous advances in our understanding of how normal cells transform to cancer and the importance of signaling pathways in cancer initiation and progression. Therefore, proteomics technologies must be improved for more global analysis of protein content of cells, tissues and body fluids as well as the posttranslational modifications to allow for proper detections and validation. In Cancer Proteomics, the authors collectively provide the current status of proteomics in cancer therapy and offers the existing technologies used in proteomics that allow for protein profiling and for the identification of druggable targets in human samples. Mass spectrometry based protein characterization and protein microarrays hold great promise of predicting response to specific drugs in cancer therapy. Insightful to the reader with broad perspectives on topics related to the use of proteomic strategies in cancer therapy, Cancer Proteomics offers anticipated challenges that may arise from its application in daily practice.
Contents
Part I. Proteomics Technologies -- Current and Emerging Mass Spectrometry Instrumentation and Methods for Proteomic Analyses -- Part II. Cell Signaling Proteomics -- Integration of Genomics and Proteomics in Dissecting p53 Signaling -- Proteomic Profiling of Tyrosine Kinases as Pharmacological Endpoints for Targeted Cancer Therapy -- Part III. Tumor Proteomics -- Oncoproteomics for Personalized Management of Cancer -- Application of Serum and Tissue Proteomics to Understand and Detect Solid Tumors -- Insight on Renal Cell Carcinoma Proteome -- Proteomics in Lung Cancer -- Proteomic Strategies of Therapeutic Individualization and Target Discovery in Acute Myeloid Leukemia -- New Tumor Biomarkers: Practical Considerations Prior to Clinical Application -- Part IV. Bioinformatics and Regulatory Aspects of Proteomics -- Annotating the Human Proteome: From Establishing a Parts List to a Tool for Target Identification -- Regulatory Issues in the Co-Development of Oncology Drugs and Proteomic Tests: An Overview.
Format
e-Book
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Clinician's Manual on Myelodysplastic Syndromes

http://libcat.nshealth.ca/permalink/provcat40647
Alan List. Current Medicine Group , c2008.
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An overview of diagnosis and current management of myelodysplastic syndromes. Reviews the performance of the pharmacological treatments currently available and analyses the potential for new treatments. High quality clinical photos and figures to enhance descriptions and improve reader comprehension.
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Author
List, Alan
Responsibility
Alan List
Place of Publication
London, England
Publisher
Current Medicine Group
Date Published
c2008
Physical Description
1 online resource (vii, 60 p.)
ISBN
9781858734279 (print ed.)
9781907673368
Subjects (MeSH)
Myelodysplastic syndromes
Other Subjects
; Medicine & Public Health
Hematology
Oncology
Notes
Reprinted 2009, 2010.
Abstract
An overview of diagnosis and current management of myelodysplastic syndromes. Reviews the performance of the pharmacological treatments currently available and analyses the potential for new treatments. High quality clinical photos and figures to enhance descriptions and improve reader comprehension.
Contents
1. Introduction to myelodysplastic syndromes -- 2. Etiology and pathophysiology -- 3. Signs and symptoms of myelodysplastic syndromes -- 4. Clinical assessment and diagnosis -- 5. Classification of myelodysplastic syndromes -- 6. Management of myelodysplastic syndromes.
Format
e-Book
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Molecular pain

http://libcat.nshealth.ca/permalink/provcat40968
Min Zhuo, editor. Higher Education Press , c2007.
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Pain is a major health concern and a growing field of research. Molecular biologists have made rapid progress in finding relationships between genetics and pain, and Molecular Pain is the first book specifically written to bring this research to doctors and pain scientists. Unlike traditional textbooks, this book utilizes basic neuroscience to explain the mechanisms of pain. It explores current pain medicine as well as alternative treatments for chronic pain, such as acupuncture. Edited by a…
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Other Authors
Zhuo, Min
Responsibility
Min Zhuo, editor
Place of Publication
Beijing, China
Publisher
Higher Education Press
Date Published
c2007
Physical Description
1 online resource (iii, 492 p. : ill.)
ISBN
9780387752686 (print ed.)
9780387752693
Subjects (MeSH)
Pain - drug therapy
Pain - physiopathology
Abstract
Pain is a major health concern and a growing field of research. Molecular biologists have made rapid progress in finding relationships between genetics and pain, and Molecular Pain is the first book specifically written to bring this research to doctors and pain scientists. Unlike traditional textbooks, this book utilizes basic neuroscience to explain the mechanisms of pain. It explores current pain medicine as well as alternative treatments for chronic pain, such as acupuncture. Edited by a leading neuroscientist and written by international experts, Molecular Pain is a concise and comprehensive review of recent progress in the field of pain.
Contents
Genes, Neurons and Neurotransmission -- Genes and Neurons -- Synapses: Coupling of Presynaptic Voltage-gated Ca2+ Channels to Vesicular Release of Neurotransmitter -- Synaptic Vesicle Cycle at Nerve Terminals -- Glutamate, Excitatory Transmission and Pain -- Postsynaptic Excitatory Transmission -- Kainate Receptors -- Exciatory Amino Acid Neurotransmitter -- Spinal Glutamate Receptors -- Glutamate Kainate Receptor in Pain Transmission and Modulation -- Neuropeptides, ATP, Retrograde Messengers and Opioids -- Neuropeptides -- ATP and Its Receptors in Pain -- Opioid Receptors -- Retrograde Messengers -- Inhibitory Transmission and Plasticity -- Postsynaptic Signaling and Gene Regulation -- Protein Kinases and Phosphatases -- Activity-dependent Gene Regulation: How Do Synapses Talk to the Nucleus and Fine-tune Neuronal Outputs? -- Second Messenger Pathways in Pain -- Genetic Approaches for the Study of Pain -- Peripheral Nociceptor, Amygdala and Fear -- Peripheral Nociceptors -- Amygdala—Pain Processing and Pain Modulation -- Fear Learning -- Spinal Plasticity, Reorganization and Chronic Pain -- Silent Glutamatergic Synapses and Long-term Facilitation in Spinal Dorsal Horn Neurons -- Anatomical Changes in the Spinal Dorsal Horn after Peripheral Nerve Injury -- Spinal Microglia in Neuropathic Pain -- Cortical Plasticity, Reorganization and Amputation -- ACC Plasticity -- Reorganization of the Sensorimotor System after Injury -- Endogenous Analgesia and Other Form of Analgesia -- Eudogenous Biphasic Modulation -- Paradoxical Analgesic and Hyperalgesic Effects of Stress -- Acupuncture Analgesia -- Mechanisms of Opioid Tolerance -- Models for Studying Pain and Searching for Pain Killers -- Models in Pain Research -- Models for Studying Pain and Searching for Pain Killers in Vitro Electrophysiological Studies of Pain -- Whole-cell Patch-clamp Recording in Vivo -- Basic Mechanisms of Clinically Used Drugs.
Format
e-Book
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