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Contemporary Treatment of Erectile Dysfunction : A Clinical Guide

http://libcat.nshealth.ca/permalink/provcat40203
Tobias S. Köhler, Kevin T. McVary, editors. (2nd ed.) Springer International Publishing : Imprint: Humana Press , c2016.
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Now in a revised and expanded second edition, this comprehensive clinical guide remains a state-of-the-art synthesis of the literature, covering all aspects of treating erectile dysfunction (ED) and other related male sexual dysfunctions. Cardiovascular, hormonal, psychological and lifestyle factors are each considered in diagnosis and treatment, which includes pharmacological, surgical and prosthetic management strategies. The effects of prostate cancer and its treatment are also discussed, as…
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Other Authors
Köhler, Tobias S
McVary, Kevin T
Responsibility
Tobias S. Köhler, Kevin T. McVary, editors
Edition
2nd ed.
Place of Publication
Cham
Publisher
Springer International Publishing : Imprint: Humana Press
Date Published
c2016
Physical Description
1 online resource (xvi, 387 p. : 77 illus., 58 illus. in color)
Series
Contemporary Endocrinology
Series Title
Contemporary endocrinology (Totowa, N.J.)
ISBN
9783319315850 (print ed.)
9783319315874
Subjects (MeSH)
Erectile dysfunction - therapy
Abstract
Now in a revised and expanded second edition, this comprehensive clinical guide remains a state-of-the-art synthesis of the literature, covering all aspects of treating erectile dysfunction (ED) and other related male sexual dysfunctions. Cardiovascular, hormonal, psychological and lifestyle factors are each considered in diagnosis and treatment, which includes pharmacological, surgical and prosthetic management strategies. The effects of prostate cancer and its treatment are also discussed, as are Peyronie's disease, priapism and ejaculatory disorders. New chapters in this edition discuss the profound effects of lifestyle change on sexual function, alternative and internet drugs that affect sexual function, endovascular approaches to ED, penile length considerations, the effect of radiation on erectile function, and optimizing ED research. Presenting a better understanding of what causes erectile dysfunction and the effective medications and non-medication treatments used to treat the condition, this invaluable title offers all physicians, residents, and fellows and even medical students and other health professionals such as nurse practitioners and physician assistants an essential reference for enhancing diagnosis and treatment of this common and debilitating disorder.
Contents
Animal Models for the Study of Erectile Function and Dysfunction -- Normal Erectile Physiology -- Psychological Aspects of Erectile Dysfunction -- Epidemiology of Erectile Dysfunction and Key Risk Factors -- Erectile Dysfunction: Etiology and Risk Factors -- Making the Diagnosis of Erectile Dysfunction -- Hormonal Evaluation and Therapy of Erectile Dysfunction -- Effects of Lifestyle Changes and Testosterone Therapy on Erectile Function -- Cardiovascular Issues in the Treatment of Erectile Dysfunction -- Alternative and Internet Drugs That Affect Sexual Function -- Prescription Medications That Affect Sexual Function -- Oral Prescription Therapy for Erectile Dysfunction -- Vacuum Therapy for Erectile Dysfunction -- Self-Injection, Transurethral, and Topical Therapy in Erectile Dysfunction -- Penile Prosthesis -- Endovascular Approaches to Penile Arterial Revascularization for Vasculogenic Erectile Dysfunction -- The Effect of Radical Prostatectomy on Sexual Function -- The Effect of Radiation on Erectile Function -- Penile Length: Natural History, Preservation, and Recovery -- Penile Rehabilitation After Prostate Cancer Treatments -- Peyronie's Disease: Natural History, Diagnosis, and Medical Therapy -- Injection Therapy for Peyronie's Disease -- Peyronie's Disease: Surgical Therapy -- Management of Priapism -- Ejaculatory Disorders -- Optimizing Research in Erectile Dysfunction.
Format
e-Book
Location
Online
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Endocrine hypertension : underlying mechanisms and therapy

http://libcat.nshealth.ca/permalink/provcat32443
Christian A Koch, George P Chrousos, editors. Humana Press , c2013.
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The prevalence of hypertension is almost three times as high as that of diabetes mellitus type 2, with both conditions being major risk factors for stroke, ischemic heart disease, cardiac arrhythmias, and heart failure. The exact prevalence of hypertension related to hormonal derangements (endocrine hypertension) is not known but estimated to affect less than 15% of hypertensive patients. Recent scientific discoveries have increased the understanding of the pathophysiologic mechanisms of hypert…
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Other Authors
Chrousos, George P
Koch, Christian A
Responsibility
Christian A Koch, George P Chrousos, editors
Place of Publication
New York, NY
Publisher
Humana Press
Date Published
c2013
Physical Description
1 online resource (xiii, 317 p. : 33 ill., 26 ill. in color)
Series Title
Contemporary endocrinology (Totowa, N.J.)
ISBN
9781607615484
Subjects (MeSH)
Adrenal gland diseases - etiology
Hypertension - etiology
Hypertension - therapy
Subjects (LCSH)
Cardiology
Endocrinology
Internal medicine
Nephrology
Obstetrics
Urology
Abstract
The prevalence of hypertension is almost three times as high as that of diabetes mellitus type 2, with both conditions being major risk factors for stroke, ischemic heart disease, cardiac arrhythmias, and heart failure. The exact prevalence of hypertension related to hormonal derangements (endocrine hypertension) is not known but estimated to affect less than 15% of hypertensive patients. Recent scientific discoveries have increased the understanding of the pathophysiologic mechanisms of hypertension. In Endocrine Hypertension, a renowned panel of experts provides a comprehensive, state-of-the-art overview of this disorder, discussing when to assign an endocrine cause in one of many conditions that may present with hypertension. The first part of Endocrine Hypertension is dedicated to adrenal causes. The second part of the volume concerns potential nonadrenal causes of hypertension, such as growth hormone excess or deficiency, primary hyperparathyroidism, vitamin D deficiency, testosterone deficiency, insulin resistance, obesity-associated hypertension, and the role of central mineralocorticoid receptors and cardiovascular disease. An important contribution to the literature, Endocrine Hypertension is an indispensable reference not only for endocrinologists, diabetologists, and adrenal investigators, but also for translational scientists and clinicians from cardiology, internal medicine, pediatrics, family medicine, geriatrics, urology, and reproductive medicine / gynecology.
Contents
Part I. Adrenal Hypertension -- Part II. Other Potential Causes of Endocrine Hypertension -- Index.
Format
e-Book
Location
Online
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Pediatric endocrinology : a practical clinical guide

http://libcat.nshealth.ca/permalink/provcat32587
Sally Radovick, Margaret H. MacGillivray, editors. (2nd ed.) Humana Press , c2013.
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A state-of-the-art and concise guide to the clinical management of pediatric endocrine disorders, the second edition of the highly regarded Pediatric Endocrinology: A Practical Clinical Guide covers the most common and challenging conditions seen by practicing endocrinologists and primary care physicians, including growth, hypothalamic, pituitary, adrenal, thyroid, calcium and bone, and reproductive disorders, as well as metabolic syndromes. This expanded second edition includes new topics bei…
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Other Authors
MacGillivray, Margaret H
Radovick, Sally
Responsibility
Sally Radovick, Margaret H. MacGillivray, editors
Edition
2nd ed.
Place of Publication
New York, NY
Publisher
Humana Press
Date Published
c2013
Physical Description
1 online resource (xv, 624 p. : 82 ill., 33 ill. in color)
Series Title
Contemporary endocrinology (Totowa, N.J.)
ISBN
9781607613954
Subjects (MeSH)
Adolescent
Child
Endocrine System Diseases
Infant
Subjects (LCSH)
Endocrinology
Pediatrics
Abstract
A state-of-the-art and concise guide to the clinical management of pediatric endocrine disorders, the second edition of the highly regarded Pediatric Endocrinology: A Practical Clinical Guide covers the most common and challenging conditions seen by practicing endocrinologists and primary care physicians, including growth, hypothalamic, pituitary, adrenal, thyroid, calcium and bone, and reproductive disorders, as well as metabolic syndromes. This expanded second edition includes new topics being seen more commonly in pediatric endocrinology practices related to obesity and type 2 diabetes mellitus and lipid disorders. Each chapter contains an introductory discussion of the problem, a review of the clinical features that characterize it, the criteria needed to establish a diagnosis, and a comprehensive therapy section delineating the risks and benefits of the best therapeutic options available. Invaluable tables summarize the critical factors in etiology, clinical presentation, diagnosis, and therapeutic dosages. Pediatric Endocrinology: A Practical Clinical Guide, Second Edition, is a comprehensive resource for all clinicians concerned with the myriad endocrinologic disorders seen in children and adolescents
Contents
Part I: Growth Disorders -- Childhood Growth Hormone Deficiency and Hypopituitarism -- Growth Hormone Insensitivity -- Skeletal Dysplasias -- Idiopathic Short Stature -- Growth Hormone Treatment Of The Short Child Born Small For Gestational Age -- Growth Hormone Therapy in Children with Prader-Willi Syndrome -- Turner Syndrome -- Management of Adult with Childhood Onset Growth Hormone Deficiency -- Part II: Hypothalamic and Pituitary Disorders -- Diabetes Insipidus -- Management of Acute and Late Endocrine Effects Following Childhood Cancer Treatment -- Endocrinologic Sequelae of Anorexia Nervosa -- Part III: Adrenal Disorders -- Adrenal Insufficiency -- Congenital Adrenal Hyperplasia -- Cushing Syndrome in Childhood -- Part IV: Thyroid Disorders -- Congenital Hypothyroidism -- Autoimmune Thyroid Disease -- Non-Thyroidal Illness Syndrome -- Resistance to Thyroid Hormone and TSH Receptor Mutations -- Thyroid Neoplasia -- Part V: Mineral and Bone Disorders -- Abnormalities in Calcium Homeostasis -- Rickets: The Skeletal Disorders of Impaired Calcium or Phosphate Availability -- Part VI: Reproductive Disorders and Contraception -- Turner Syndrome, Kallmann Syndrome and Noonan Syndrome -- Precocious Puberty: Clinical Management -- Management of Infants Born with Disorders of Sex Development -- Menstrual Disorders and Hyperandrogenism in Adolescence -- Contraception -- Part VII. Metabolic Disorders -- Hypoglycemia -- Diabetes Mellitus in Children and Adolescents -- Type II Diabetes Mellitus and Obesity in Youth -- Diagnosis and Treatment of Dyslipoproteinemias in Children and Adolescents -- Part VIII: Other Endocrine Disorders -- Autoimmune Endocrine Disorders -- Multiple Endocrine Neoplasia Syndromes -- The Endocrine Response to Critical Illness.
Format
e-Book
Location
Online
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Endocrinology of Physical Activity and Sport

http://libcat.nshealth.ca/permalink/provcat40763
edited by Naama Constantini, Anthony C. Hackney. (Second edition) Humana Press , c2013.
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Understanding the influence and interaction between physical activity and the endocrine system are of paramount importance in dealing with a multitude of health problems. In Endocrinology of Physical Activity and Sport, renowned physicians and researchers provide a comprehensive and expanded update on the scientific, clinical and practical components of endocrinology as related to sport and exercise. The authors thoroughly review what is known about how such activity affects the endocrine syste…
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Other Authors
Constantini, Naama
Hackney, Anthony C
Responsibility
edited by Naama Constantini, Anthony C. Hackney
Edition
Second edition
Alternate Title
Sports endocrinology
Place of Publication
Totowa, NJ
Publisher
Humana Press
Date Published
c2013
Physical Description
1 online resource (xi, 558 p. : 56 illus., 10 illus. in color)
Series Title
Contemporary endocrinology (Totowa, N.J.)
ISBN
9781627033138 (print ed.)
9781627033145
Subjects (MeSH)
Endocrine glands - physiology
Exercise - physiology
Homeostasis - physiology
Hormones - physiology
Sports - physiology
Notes
Rev. ed. of: Sports endocrinology / edited by Michelle P. Warren and Naama W. Constantini. c2000.
Abstract
Understanding the influence and interaction between physical activity and the endocrine system are of paramount importance in dealing with a multitude of health problems. In Endocrinology of Physical Activity and Sport, renowned physicians and researchers provide a comprehensive and expanded update on the scientific, clinical and practical components of endocrinology as related to sport and exercise. The authors thoroughly review what is known about how such activity affects the endocrine system and how in turn these hormonal responses affect many other organs and systems of the body. In addition, aspects of endocrinology in non-glandular tissue which have endocrine actions are addressed; for example, adipocytes and the release of leptin and related adipocytokines. Further, a wide range of clinically related topics such as athletic amenorrhea, osteopenia, sarcopenia, and hypogonadism are included. This new edition critically integrates what is known about the complex interaction of the endocrine system in the sports context and will again prove immensely valuable to all physicians and clinical investigators treating those active in sports today.
Contents
Methodological Considerations in Exercise Endocrinology -- Exercise and Endogenous Opiates -- The Effect of Exercise on the Hypothalamo-Pituitary-Adrenal Axis -- Impact of Chronic Training on Pituitary Hormone Secretion in the Human -- Exercise and the GH-IGF-I axis -- Exercise and Thyroid Function -- The Male Reproductive System, Exercise and Training: Endocrine Adaptations -- Exercise and the Hypothalamus. Ovulatory Adaptations -- Adrenergic Regulation of Energy Metabolism -- Energy Balance and Weight Control (Male and Female): Considerations -- Exercise Training in the Normal Female: Effects of Low Energy -- Availability on Reproductive Function -- Ghrelin Responses to Acute Exercise and Training -- Hormonal Regulation of Fluid and Electrolyte Homeostasis During Exercise -- Hormonal Regulations of the Effects of Exercise on Bone: Positive and Negative Effects -- Interrelations Between Acute and Chronic Exercise Stress and the Immune and Endocrine Systems -- Effect of Female Reproductive Hormones on Sports Performance -- Exercise and Pregnancy: Hormonal Considerations -- Vitamin D and Exercise Performance -- The effects of altitude on the hormonal response to physical exercise -- An Introduction to Circadian Endocrine Physiology: Implications for Exercise and Sports Performance -- Physical Activity and Mood. The Endocrine Connection -- Endocrine Responses to Acute and Chronic Exercise in the Developing Child -- Exercise in Older Adults: The Effect of Age on Exercise Endocrinology -- Oncology Patients and Aerobic Exercise: Immune System, Endocrine System, and Soluble Factor Responses -- Diabetes and Exercise -- Extreme Sports and Type 1 Diabetes Mellitus: An oxymoron or a growing reality? -- The Endocrine System in Overtraining -- Hormones as Performance-Enhancing Agents.
Format
e-Book
Location
Online
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When Puberty is Precocious : Scientific and Clinical Aspects

http://libcat.nshealth.ca/permalink/provcat28784
edited by Ora H. Pescovitz, Emily C. Walvoord. Humana Press , c2007.
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When Puberity is Precocious: Scientific and Clinical Aspects provides a unique continuum of expertise, looking at puberty from anthropologic, epidemiologic, clinical, and molecular perspectives. The volume addresses broad pubertal changes in the general population while at the same time providing in depth information about specific disorders of puberty and the latest management changes. The text is divided into seven parts. The first is an in-depth investigation into neuroendocrine control of p…
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Author
Pescovitz, Ora H
Other Authors
Walvoord, Emily C
Responsibility
edited by Ora H. Pescovitz, Emily C. Walvoord
Place of Publication
Totowa
Publisher
Humana Press
Date Published
c2007
Physical Description
1 online resource (468 p.)
Series Title
Contemporary endocrinology (Totowa, N.J.)
ISBN
9781597454995 [corrected]
Subjects (MeSH)
Endocrine disruptors - therapeutic use
Psychosexual development - physiology
Puberty, precocious - etiology
Puberty, precocious - physiopathology
Subjects (LCSH)
Developmental biology
Endocrinology
Pediatrics
Abstract
When Puberity is Precocious: Scientific and Clinical Aspects provides a unique continuum of expertise, looking at puberty from anthropologic, epidemiologic, clinical, and molecular perspectives. The volume addresses broad pubertal changes in the general population while at the same time providing in depth information about specific disorders of puberty and the latest management changes. The text is divided into seven parts. The first is an in-depth investigation into neuroendocrine control of puberty, the second looks at secular trends and the onset of puberty, and the third provides an examination into isolated breast development. The fourth section covers adrenal abnormalities and puberty, the next two sections include chapters on gonadotropinÇÖs effects, and the final section is a looks at environmental effects on puberty. Comprehensive and timely, When Puberity is Precocious: Scientific and Clinical Aspects will become an essential reference for endocrinologists and internists with an interest in precocious puberty.
Contents
1. Control puberty in rodents : special focus on the female / Sabine Heger and Sergio R. Ojeda -- 2. Control of puberty in non-human primates / Tony M. Plant -- 3. Control of puberty in humans / Dennis M. Styne and Melvin M. Grumbach -- 4. Genetic regulation of the variation in pubertal timing / Craig A. Hodges and Mark R. Palmert -- 5. Puberty is starting earlier in the 21st century / Marcia E. Herman-Giddens -- 6. BMI and the onset of puberty / Paul Kaplowitz -- 7. Puberty timing remains unchanged / Peter A. Lee and Christopher P. Houk -- 8. Premature thelarche / Linda A. DiMeglio and Adda Grimberg -- 9. Gynecomastia : epidemiology, pathophysiology, and management / Samar N. Rahhal and John S. Fuqua -- 10. Premature adrenarche : harbingers and consequences / Alicia Belgorosky, Maria Sonia Baquedano, Gabriela Guercio and Marco A. Rivarola -- 11. Pubertal consequences of being born small for gestational age / Dyanne A. Wilson, Wayne S. Cutfield and Paul L. Hofman -- 12. Congenital adrenal hyperplasia / Lenore S. Levine, Sharon E. Oberfield and Lauren Antler -- 13. Polycystic ovary syndrome in the peripubertal period / Selma Feldman Witchel -- 14. Psychological and social problems in children with premature adrenarche and precocious puberty / Lorah D. Dorn -- 15. Etiology of gonadotropin-dependent precocious puberty / Erik A. Imel and Kathleen R. Bethin -- 16. Treatment of gonadotropin-dependent precocious puberty / Zeina M. Nabhan and Emily C. Walvoord -- 17. McCune-Albright syndrome : pathophysiology, diagnosis, and management / Tamara S. Hannon and Erica A. Eugster -- 18. Familial male-limited precocious puberty / Nerissa C. Kreher -- 19. Gonadal and adrenal tumors / Inessa M. Gelfand, MD and Nadine G. Haddad -- 20. The Role of Endocrine Disruptors in Pubertal Development / Todd D. Nebesio, MD and Ora H. Pescovitz -- 21. Precocious puberty in internationally adopted girls / Grete Teilmann, Anne-Simone Parent, Niels E. Skakkebtek and Jean-Pierre Bourguignon.
Format
e-Book
Location
Online
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Dyslipidemias : Pathophysiology, Evaluation and Management

http://libcat.nshealth.ca/permalink/provcat39039
Abhimanyu Garg, editor. Humana Press , c2015.
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Dyslipidemias: Pathophysiology, Evaluation and Management provides a wealth of general and detailed guidelines for the clinical evaluation and management of lipid disorders in adults and children. Covering the full range of common through rare lipid disorders, this timely resource offers targeted, practical information for all clinicians who care for patients with dyslipidemias, including general internists, pediatric and adult endocrinologists, pediatricians, lipidologists, cardiologists, inte…
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Other Authors
Garg, Abhimanyu
Responsibility
Abhimanyu Garg, editor
Place of Publication
Totowa, NJ
Publisher
Humana Press
Date Published
c2015
Physical Description
1 online resource (xvi, 525 p. : 127 illus., 101 illus. in color)
Series
Contemporary Endocrinology
Series Title
Contemporary endocrinology (Totowa, N.J.)
ISBN
9781607614234 (print ed.)
9781607614241
Subjects (MeSH)
Dyslipidemias - physiopathology
Dyslipidemias - therapy
Abstract
Dyslipidemias: Pathophysiology, Evaluation and Management provides a wealth of general and detailed guidelines for the clinical evaluation and management of lipid disorders in adults and children. Covering the full range of common through rare lipid disorders, this timely resource offers targeted, practical information for all clinicians who care for patients with dyslipidemias, including general internists, pediatric and adult endocrinologists, pediatricians, lipidologists, cardiologists, internists, and geneticists. For the last twenty years, there has been a growing recognition worldwide of the importance of managing dyslipidemia for the primary and secondary prevention of atherosclerotic vascular disease, especially coronary heart disease. This has been mainly due to the publication of the guidelines of National Cholesterol Education Program's Adult Treatment Panel and Pediatric Panel from the United States. These guidelines have stimulated generation of similar recommendations from all over the world, particularly Europe, Canada, Australia and Asia. Developed by a renowned group of leading international experts, the book offers state-of-the-art chapters that are peer-reviewed and represent a comprehensive assessment of the field. A major addition to the literature, Dyslipidemias: Pathophysiology, Evaluation and Management is a gold-standard level reference for all clinicians who are challenged to provide the best care and new opportunities for patients with dyslipidemias.
Contents
Lipoprotein Physiology -- Epidemiology of Blood Lipids and Lipoproteins -- Lipoprotein(a) -- Lipoproteins and Cardiovascular Disease Risk -- Detection and Treatment of Children and Adolescents with Dyslipidemia -- Type 2 Diabetes Mellitus and Dyslipidemia -- Type 1 Diabetes Mellitus and Dyslipidemia -- Dyslipidemia in Chronic Kidney Disease and Nephrotic Syndrome -- Dyslipidemia in HIV-infected Patients -- Monogenic Hypercholesterolemias -- Primary Hypertriglyceridemia -- Genetic Disorders of HDL Metabolism -- Sitosterolemia and Other Rare Sterol Disorders -- Genetic Abetalipoproteinemia & Hypobetalipoproteinemia -- Drug-induced Dyslipidemia -- Lipodystrophies and Dyslipidemias -- Novel Genes for Dyslipidemias: Genome-Wide Association Studies -- Perspectives on Cholesterol Guidelines -- Nutrition and Coronary Heart Disease Prevention -- Phytosterol Therapy -- N-3 Fatty Acids: Role in Treating Dyslipidemias and Preventing Cardiovascular Disease -- Polyphenols for Cholesterol Management -- Dietary Supplements for Cholesterol Management -- Statins: Risk-Benefits and Role in Treating Dyslipidemias -- Fibrates: Risk-Benefits and Role in Treating Dyslipidemias -- Niacin: Risk-Benefits and Role in Treating Dyslipidemias -- Bile Acid Sequestrants: Risk-Benefits and Role in Treating Dyslipidemias -- Cholesterol Absorption Inhibitor-Ezetimibe: Risk-Benefits and Role in Treating Dyslipidemias -- Low Density Lipoprotein (LDL) Apheresis -- Novel Lipid Lowering Agents.
Format
e-Book
Location
Online
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Endocrine Disruptors and Puberty

http://libcat.nshealth.ca/permalink/provcat30999
Evanthia Diamanti-Kandarakis, Andrea C. Gore, editors. Humana Press , c2012.
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Endocrine disruption represents one of the most controversial environmental issues of our time. Mounting evidence stemming from more than 10 years of experimental, epidemiological and clinical studies has transformed the once generally discounted subject of endocrine disruptors into an issue of tremendous concern not only within the scientific community but among society as a whole.Following initial evidence from basic research, endocrine disruption in humans has now emerged as a major medical …
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Other Authors
Diamanti-Kandarakis, Evanthia
Gore, Andrea C
Responsibility
Evanthia Diamanti-Kandarakis, Andrea C. Gore, editors
Place of Publication
New York, NY
Publisher
Humana Press
Date Published
c2012
Physical Description
1 online resource (xvii, 378 p. : 18 ill., 11 ill. in color)
Series Title
Contemporary endocrinology (Totowa, N.J.)
ISBN
9781607615613
Subjects (MeSH)
Endocrine disruptors - adverse effects
Environmental exposure - adverse effects
Environmental pollutants - adverse effects
Puberty - drug effects
Subjects (LCSH)
Endocrinology
Toxicology
Abstract
Endocrine disruption represents one of the most controversial environmental issues of our time. Mounting evidence stemming from more than 10 years of experimental, epidemiological and clinical studies has transformed the once generally discounted subject of endocrine disruptors into an issue of tremendous concern not only within the scientific community but among society as a whole.Following initial evidence from basic research, endocrine disruption in humans has now emerged as a major medical challenge. In this respect, puberty, a crucial developmental stage, has been definitively identified as a key window of vulnerability with regard to endocrine disruptors. Written by leading authorities in the field, Endocrine Disruptors and Puberty offers an engaging and comprehensive overview of this fascinating and rapidly growing problem. An indispensable resource for all clinicians and scientists interested in this challenging endocrinologic topic, Endocrine Disruptors and Puberty is a timely contribution that will help navigate a path toward understanding the problem and developing solutions.
Contents
Introduction to endocrine disruptors and puberty -- In utero exposure to environmental chemicals: Lessons from maternal cigarette smoking and its effects on gonad development and puberty -- Reproductive neuroendocrine targets of developmental exposure to endocrine disruptors -- Endocrine disruptors and puberty disorders from mice to men (and women) -- Thyroid hormone regulation of mammalian reproductive development and the potential impact of endocrine disrupting chemicals -- Developmental exposure to endocrine disruptors and ovarian function -- Developmental exposure to environmental endocrine disruptors and adverse effects on mammary gland development -- Developmental exposure to endocrine disruptors and male urogenital tract malformations -- EDC exposures and the development of reproductive and non-reproductive behaviors -- Adipocytes as target cells for endocrine disruption -- Altered glucose homeostasis resulting from developmental exposures to endocrine disruptors -- Developmental exposure to endocrine disrupting chemicals: Is there a connection with birth and childhood weights? -- The impact of endocrine disruptors on female pubertal timing -- The influence of endocrine disruptors on male pubertal timing -- Secular trends in pubertal timing: a role for environmental chemical exposure?
Format
e-Book
Location
Online
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Ghrelin in Health and Disease

http://libcat.nshealth.ca/permalink/provcat31026
Roy G. Smith, Michael O. Thorner, editors. Humana Press , c2012.
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Ghrelin, the endogenous ligand for the growth hormone secretagogue (GHS) receptor, is critical in the control of food intake and energy balance. The ghrelin receptors are now known to have important physiological properties as modulators of growth hormone release, appetite, glucose homeostasis, metabolism, immune function, neurotransmitter activity, cognitive function and neurodegeneration. Bringing all of this information together in the first comprehensive text on the topic, Ghrelin in Health…
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Other Authors
Smith, Roy G
Thorner, Michael O
Responsibility
Roy G. Smith, Michael O. Thorner, editors
Place of Publication
New York, NY
Publisher
Humana Press
Date Published
c2012
Physical Description
1 online resource (xiv, 290 p. : 44 ill., 3 ill. in color)
Series Vol.
v. 10
Series Title
Contemporary endocrinology (Totowa, N.J.)
ISBN
9781617799037
Subjects (MeSH)
Ghrelin - metabolism
Ghrelin - physiology
Subjects (LCSH)
Endocrinology
Nutrition
Abstract
Ghrelin, the endogenous ligand for the growth hormone secretagogue (GHS) receptor, is critical in the control of food intake and energy balance. The ghrelin receptors are now known to have important physiological properties as modulators of growth hormone release, appetite, glucose homeostasis, metabolism, immune function, neurotransmitter activity, cognitive function and neurodegeneration. Bringing all of this information together in the first comprehensive text on the topic, Ghrelin in Health and Disease provides a state-of-the-art synthesis of the latest work in this area for physicians and physician-scientists. This volume addresses the unique property of ghrelin as a modulator of function. Such a property provides potential utility for safe intervention in a wide variety of disease states. Indeed as we learn more about the basic physiology of ghrelin, the potential for treating new disease targets emerge requiring validation in the clinic. Each chapter in this volume is authored by a leading investigator in the field. The introductory chapter sets the background for the book and provides a superb overview of the relevance of ghrelin to physiology, describing how the discovery of ghrelin has prompted us to completely rethink traditional physiology. The authors conclude their chapters by critically addressing the future translational aspects of ghrelin biology and outlining what key basic research and clinical questions remain to be addressed. An invaluable resource, Ghrelin in Health and Disease distinguishes itself as the first comprehensive title covering all of the molecular and clinical issues relating to ghrelin and advancing our clinical understanding of obesity, growth, and reproductive pathogenesis.
Contents
[Machine generated contents note] 1. Ghrelin: A History of Its Discovery / Johannes D. Veldhuis -- 2. Enzymatic Processing of Ghrelin Precursor / Kenji Kangawa -- 3. Ghrelin’s Novel Signaling in Islet ß-Cells to Inhibit Insulin Secretion and Its Blockade As a Promising Strategy to Treat Type 2 Diabetes / Toshihiko Yada -- 4. Gastric Ghrelin in the Regulation of Appetite and Metabolism / Felipe F. Casanueva -- 5. Ghrelin Regulation of AMPK in the Hypothalamus and Peripheral Tissues / Marta Korbonits -- 6. Ghrelin: Neuropeptide Regulator of Metabolism / Michael Alexander Cowley -- 7. GOAT and the Regulation of Energy and Glucose Homeostasis / Jenny Tong -- 8. Ghrelin Regulation of Sleep, Circadian Clock, and Body Temperature / Levente Kapas -- 9. Ghrelin Regulation of Learning, Memory, and Neurodegeneration / Tamas L. Horvath -- 10. Ghrelin Antagonism: A Potential Therapeutic Target for Addictive Behaviour Disorders / Suzanne L. Dickson -- 11. Ghrelin Receptor Agonists in Cachexia of Human Aging / Michael O. Thorner -- 12. Use of Ghrelin and Ghrelin Receptor Agonists in Cancer- and Chemotherapy-Induced Cachexia / Jose M. Garcia -- 13. Ghrelin in Cachexia Associated with End-Stage Renal Disease / Stephen Bloom -- 14. Ghrelin Suppression of Autoimmune Encephalomyelitis / Takashi Yamamura -- 15. Physiological Roles of Des-Acyl Ghrelin / Aart J. van der Lely -- 16. Ghrelin Receptor (GHSR1a), But Not Ghrelin, Is Essential for Dopamine Receptor-2 (DRD2) Agonist-Induced Anorexia / Roy G. Smith.
Format
e-Book
Location
Online
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Cardiovascular endocrinology : shared pathways and clinical crossroads

http://libcat.nshealth.ca/permalink/provcat23889
Fonseca, Vivian A. Humana Press , 2009.
Call Number
WG 102 C267 2009
Location
Halifax Infirmary
Call Number
WG 102 C267 2009
Author
Fonseca, Vivian A
Place of Publication
Totowa, NJ
Publisher
Humana Press
Date Published
2009
Physical Description
257 p.
Series Title
Contemporary endocrinology (Totowa, N.J.)
ISBN
9781588298508
Subjects (MeSH)
Endocrine System Diseases
Format
Book
Location
Halifax Infirmary
Loan Period
3 weeks
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Stem Cells in Endocrinology

http://libcat.nshealth.ca/permalink/provcat28086
edited by Linda B. Lester. Humana Press , c2005.
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Location
Online
Available Online
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Author
Lester, Linda B
Responsibility
edited by Linda B. Lester
Place of Publication
Totowa, NJ
Publisher
Humana Press
Date Published
c2005
Series Title
Contemporary endocrinology (Totowa, N.J.)
ISBN
9781592599004
Subjects (MeSH)
Endocrine System Diseases - therapy
Stem cells
Subjects (LCSH)
Endocrinology
Gene therapy
Format
e-Book
Location
Online
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