Skip header and navigation

9 records – page 1 of 1.

Understanding Hughes Syndrome : Case Studies for Patients

http://libcat.nshealth.ca/permalink/provcat40948
Graham R. V. Hughes. Springer , c2009.
Available Online
View e-Book
Location
Online
Antiphospholipid Syndrome or Hughes Syndrome was the major medical discovery of the late 20th century; for many it is still deemed a new disease. As a result many people are now living with the disease with little knowledge of its causes, effects and available treatments. Many of these patients are also struggling to cope with the daily demands posed by living with such an illness. Understanding Hughes Syndrome: Case Studies for Patients, presents 50 case histories, each covered independently t…
Available Online
View e-Book
Author
Hughes, Graham R. V
Responsibility
Graham R. V. Hughes
Place of Publication
London
Publisher
Springer
Date Published
c2009
Physical Description
1 online resource (xiv, 94 p.)
ISBN
9781848003767
9781848009325 (print ed.)
Subjects (MeSH)
Antiphospholipid Syndrome
Abstract
Antiphospholipid Syndrome or Hughes Syndrome was the major medical discovery of the late 20th century; for many it is still deemed a new disease. As a result many people are now living with the disease with little knowledge of its causes, effects and available treatments. Many of these patients are also struggling to cope with the daily demands posed by living with such an illness. Understanding Hughes Syndrome: Case Studies for Patients, presents 50 case histories, each covered independently to give a comprehensive view of the vast spectrum that is Antiphospholipid Syndrome. Neurological aspects and effects are covered in approximately half the text, with the remainder covering everything from repeated miscarriages to easy bruising. The provision of personal accounts of Antiphospholipid Syndrome makes this book the ultimate companion to people living with the disease; giving not only the facts but also the personal touch that many people need when coming to terms, and dealing, with their condition. Understanding Hughes Syndrome: case studies for patients is written by Graham R.V. Hughes, MD, FRCP, a world-renowned expert in the field of rheumatology, and as the name suggests discoverer of Hughes or Antiphospholipid Syndrome. Hughes is also the Head of The London Lupus Centre, Founder and Editor of the international journal Lupus, and life president of the lupus patients charity Lupus UK.
Contents
The Brain -- Late for the Wedding -- Falling Over -- Diplomatic Epilepsy -- Weak Legs -- Multiple Sclerosis -- Teenage Migraine -- Getting Only Half the Picture -- Difficult Crossword Puzzles -- Playing the Wrong Notes -- Speaking Gibberish -- I Lost My Sense of Smell -- Movement, Jerks and Twitches -- Mad Cow Disease -- St. Vitus Dance -- Parkinson's Disease -- Missing the Target -- The Headmistress Who Forgot -- "Personality Disorder" in a 4-Year-Old -- To Sleep... Perchance to Dream -- ... and Other Organs -- Collapse at the Airport -- Ballerina's Leg Ulcers -- Twenty Years On -- "Heart Attack" -- Backpacking in Australia -- Short of Breath in Scandinavia -- Easy Bruising -- Addison's Disease: 200 Years On? -- Tummy Pain -- Impotence -- Severe Leg Pain -- Pain in the Foot (Toelitis) -- The Bells Are Ringing -- The Swollen Legs -- The Computer has Crashed (The Catastrophic APS) -- Pregnancy, Miscarriage, Infertility -- Eleven Miscarriages -- Late Pregnancy Tragedy -- The Infertility Clinic -- Causes and Effects -- The Pill and I -- A Bad Back -- A Miracle -- Climbing the Andes -- Fear of Flying -- The Lambeth Walk -- The Tests are Negative! -- Aspects of Treatment -- "My Sister has Hughes Syndrome" -- Trial and Error -- "I Saved the Country Ð73,000" -- What Happened Next? -- "Your Condition Doesn't Exist" -- "I've Got My Life Back!".
Format
e-Book
Publication Type
Case Reports
Popular Works
Location
Online
thumbnail

Hughes Syndrome : Highways and Byways

http://libcat.nshealth.ca/permalink/provcat40708
Graham Hughes, Munther A Khamashta. Springer , c2013.
Available Online
View e-Book
Location
Online
Hughes Syndrome: Highways and Byways is a handy and easy-to-read guide to the main features of Hughes syndrome. There has been worldwide interest in this 'new' syndrome (first described in 1983). A clotting tendency which can potentially affect any organ in the body, it is: responsible for 1 in 5 recurrent miscarriages (now successfully treated with aspirin and heparin); responsible for 1 in 5 young (under 45) strokes; a major cause of early heart attacks; responsible for 1 in 5 deep vein throm…
Available Online
View e-Book
Author
Hughes, Graham
Other Authors
Khamashta, Munther A
Responsibility
Graham Hughes, Munther A Khamashta
Place of Publication
London
Publisher
Springer
Date Published
c2013
Physical Description
1 online resource (x, 94 p. : 15 illus., 14 illus. in color)
ISBN
9781447151609 (print ed.)
9781447151616
Subjects (MeSH)
Antiphospholipid Syndrome
Abstract
Hughes Syndrome: Highways and Byways is a handy and easy-to-read guide to the main features of Hughes syndrome. There has been worldwide interest in this 'new' syndrome (first described in 1983). A clotting tendency which can potentially affect any organ in the body, it is: responsible for 1 in 5 recurrent miscarriages (now successfully treated with aspirin and heparin); responsible for 1 in 5 young (under 45) strokes; a major cause of early heart attacks; responsible for 1 in 5 deep vein thromboses; an important cause of migraine. Hughes Syndrome: Highways and Byways is a valuable resource for professionals with an interest in the subject, as well as general practitioners and patients.
Format
e-Book
Location
Online
thumbnail

Hughes Syndrome : The Antiphospholipid Syndrome : A Guide for Students

http://libcat.nshealth.ca/permalink/provcat30818
Graham Hughes, Shirish Sangle. Springer , c2012.
Available Online
View e-Book
Location
Online
Hughes Syndrome: The Antiphospholipid Syndrome, A Guide for Students provides an in-depth analysis into the main effects of Hughes Syndrome. In 1983, Dr Graham Hughes, and his team in London, described a syndrome and subsequently developed simple blood tests to diagnose the condition. This syndrome is characterised by thrombosis (both in limbs and internal organs), headaches, memory loss, strokes and, in pregnant women, placental clotting and recurrent miscarriage. The syndrome, now known worl…
Available Online
View e-Book
Author
Hughes, Graham
Other Authors
Sangle, Shirish
Responsibility
Graham Hughes, Shirish Sangle
Place of Publication
London
Publisher
Springer
Date Published
c2012
Physical Description
1 online resource (xvii, 102 p. : 51 ill., 37 ill. in color)
ISBN
9780857297396
Subjects (MeSH)
Antiphospholipid Syndrome
Subjects (LCSH)
Immunology
Abstract
Hughes Syndrome: The Antiphospholipid Syndrome, A Guide for Students provides an in-depth analysis into the main effects of Hughes Syndrome. In 1983, Dr Graham Hughes, and his team in London, described a syndrome and subsequently developed simple blood tests to diagnose the condition. This syndrome is characterised by thrombosis (both in limbs and internal organs), headaches, memory loss, strokes and, in pregnant women, placental clotting and recurrent miscarriage. The syndrome, now known worldwide as Hughes Syndrome, or the Antiphospholipid Syndrome, is common - being responsible for example, for up to 1 in 5 cases of young stroke and more importantly, it is treatable. Hughes Syndrome: The Antiphospholipid Syndrome, A Guide for Students details the effects of Hughes Syndrome on the major organs, making it a valuable reference tool for students in training.
Contents
History -- Hughes Syndrome: Clinical features -- Hughes Syndrome: Pregnancy and infertility -- Venous thrombosis -- Migraine and stroke -- Movement disorders and seizures -- Neuropsychiatric aspects -- Spinal cord (including multiple sclerosis) and peripheral nerves -- The Heart The Arteries -- The Kidneys -- Skin -- The Eye -- Ear, nose & throat -- Lungs -- Liver and gut -- Bones and joints -- Blood -- Catastrophic APS -- Diagnosis -- Treatment -- Hughes Syndrome: The Causes–Genetics Versus Environment -- Links to other diseases -- Conclusions: The world map.
Format
e-Book
Location
Online
thumbnail

Antiphospholipid Syndrome : Insights and Highlights from the 13th International Congress on Antiphospholipid Antibodies

http://libcat.nshealth.ca/permalink/provcat30968
Doruk Erkan, Silvia S. Pierangeli, editors. Springer , c2012.
Available Online
View e-Book
Location
Online
The International Congress on Antiphospholipid Antibodies is held every three years to discuss the recent advances and future directions in Antiphospholipid Syndrome (APS). This volume collects the scientific highlights and new findings about APS that were generated from the most recent 13th Congress, held in Galveston, Texas in 2010. Chapters were written by an internationally-distinguished group of scientists from the point-of-view of multiple specialty areas. Each chapter was written in a un…
Available Online
View e-Book
Other Authors
Erkan, Doruk
Pierangeli, Silvia S
Responsibility
Doruk Erkan, Silvia S. Pierangeli, editors
Place of Publication
New York, NY
Publisher
Springer
Date Published
c2012
Physical Description
1 online resource (xvii, 312 p. : 28 ill., 20 ill. in color)
ISBN
9781461431947
Subjects (MeSH)
Antibodies, Antiphospholipid
Antiphospholipid Syndrome
Subjects (LCSH)
Immunology
Abstract
The International Congress on Antiphospholipid Antibodies is held every three years to discuss the recent advances and future directions in Antiphospholipid Syndrome (APS). This volume collects the scientific highlights and new findings about APS that were generated from the most recent 13th Congress, held in Galveston, Texas in 2010. Chapters were written by an internationally-distinguished group of scientists from the point-of-view of multiple specialty areas. Each chapter was written in a uniform and systematic basis to present the latest evidence-based research, including the basic science of APS, task force reports from the Congress on controversial aspects of APS, and future directions of APS research. This book will appeal to all clinicians involved in the treatment and management of APS patients, to residents in a variety of medical subspecialties, and to research scientists interested in a better understanding of this complex and evolving disease.
Contents
Overview of the Last 25 years and 13 International Congresses on Antiphospholipid Antibodies -- What is the Origin of Antiphospholipid Antibodies? -- What is the Genetics of Antiphospholipid Antibodies/Syndrome? -- What is the Mechanism(s) of Antiphospholipid Antibody-mediated Thrombosis? -- What is the Mechanism(s) of Antiphospholipid Antibody-mediated Pregnancy Morbidity? -- What are the Target Cells and Receptors Recognized by Antiphospholipid Antibodies? -- Task Force Report on "Criteria" Antiphospholipid Antibody Tests -- Task Force Report on "Non-Criteria" Antiphospholipid Antibody Tests -- Task Force Report on Obstetric Antiphospholipid Syndrome -- Task Force Report on Brain Involvement in Antiphospholipid Syndrome -- Task Force Report on the Management of Thrombosis in Antiphospholipid Syndrome -- Task Force Report on Catastrophic Antiphospholipid Syndrome -- Task Force Report on Non-criteria aPL Manifestations: Thrombocytopenia -- Task Force Report on Non-criteria Manifestations: Nephropathy -- Task Force Report on Non-criteria Manifestations: Cardiac Valve Disease -- Task Force Report on Non-criteria Manifestations: Skin -- Task Force Report on Antiphospholipid Syndrome Clinical Research -- What are the Potential Future Treatments in Antiphospholipid Syndrome? -- Remembrance of Predictions of Past -- What Should Patients Know about Antiphospholipid Antibodies and Antiphospholipid Syndrome?
Format
e-Book
Location
Online
thumbnail

Antiphospholipid Antibody Syndrome : From Bench to Bedside

http://libcat.nshealth.ca/permalink/provcat39119
Pier Luigi Meroni, editor. Springer , c2015.
Available Online
View e-Book
Location
Online
This book, part of the series Rare Diseases of the Immune System, offers comprehensive, up-to-date coverage of the pathophysiology and management of the antiphospholipid syndrome (APS). Immunologic and genetic aspects are discussed and the pathogenic mechanisms responsible for such phenomena as APS-mediated thrombosis and pregnancy loss or complications are explained. The main clinical manifestations and classification criteria are described and diagnostic tools, identified. Close attention is …
Available Online
View e-Book
Other Authors
Meroni, Pier Luigi
Responsibility
Pier Luigi Meroni, editor
Place of Publication
Cham
Publisher
Springer
Date Published
c2015
Physical Description
1 online resource (x, 267 p. : 19 illus., 15 illus. in color)
Series Title
Rare diseases of the immune system
ISBN
9783319110431 (print ed.)
9783319110448
ISSN
2282-6505
Subjects (MeSH)
Antibodies, Antiphospholipid
Antiphospholipid Syndrome
Abstract
This book, part of the series Rare Diseases of the Immune System, offers comprehensive, up-to-date coverage of the pathophysiology and management of the antiphospholipid syndrome (APS). Immunologic and genetic aspects are discussed and the pathogenic mechanisms responsible for such phenomena as APS-mediated thrombosis and pregnancy loss or complications are explained. The main clinical manifestations and classification criteria are described and diagnostic tools, identified. Close attention is paid to the nature of the involvement of other organs or organ systems in APS, including the nervous, endocrine, hematologic, cardiovascular, and gastrointestinal systems, the kidney, the skin, and the eye. Specific chapters describe the treatment of the different symptoms, the preventive therapies of value in avoiding recurrences, and innovative treatment approaches. The authors are senior experts in the field who are aided by younger fellows, ensuring that the book is also educationally oriented. This handy volume will be a valuable tool for postgraduates in training and professionals wishing to extend their knowledge of this specific syndrome.
Contents
1 Genetics and Origin of Antiphospholipid Syndrome -- 2 The Paradox of Lupus Anticoagulant -- 3 Antiphospholipid Antibody Mechanisms of Thrombosis -- 4 The Pathogenic Mechanisms for Antiphospholipid Antibodies (aPL)-Mediated Pregnancy Loss -- 5 Classification Criteria for the Antiphospholipid Syndrome -- 6 Non-classification Criteria -- 7 Obstetric APS -- 8 APS and the Nervous System -- 9 Antiphospholipid Syndrome (APS) and the Renal Involvement -- 10 Non-Thrombotic Hematologic Manifestations in APS -- 11 Heart and APS -- 12 Skin Involvement in Antiphospholipid Syndrome -- 13 Additional Organs Involved in Antiphospholipid Syndrome: Eye, Ear-Nose-Throat, Lung, Gastroenteric System, Endocrine Glands -- 14 Differential Diagnosis -- 15 Treatment of Thrombosis in Antiphospholipid Syndrome -- 16 Treatment of Pregnancy Complications -- 17 Antiphospholipid Antibody Carriers -- 18 New Treatments -- 19 Secondary Antiphospholipid Syndrome -- 20 The Catastrophic Antiphospholipid Syndrome.
Format
e-Book
Location
Online
thumbnail

Antiphospholipid Syndrome : Current Research Highlights and Clinical Insights

http://libcat.nshealth.ca/permalink/provcat41773
Doruk Erkan, Michael D. Lockshin, editors. Springer , 2017.
Available Online
View e-Book
Location
Online
This new edition is a comprehensive and updated resource on antiphospholipid syndrome (APS), which is an autoimmune disorder. In APS, the body recognizes certain normal components of blood and/or cell membranes as foreign substances and produces antibodies (antiphospholipid antibodies) against them. APS is associated with recurrent clotting events (thrombosis) including premature stroke, repeated miscarriages, phlebitis, venous thrombosis, and pulmonary thromboembolism. It is also associated wi…
Available Online
View e-Book
Other Authors
Erkan, Doruk
Lockshin, Michael D
Responsibility
Doruk Erkan, Michael D. Lockshin, editors
Place of Publication
Cham
Publisher
Springer
Date Published
2017
Physical Description
1 online resource (xx, 372 pages) : 18 illus., 16 illus. in color
ISBN
9783319554402 (print ed.)
9783319554426
Subjects (MeSH)
Antiphospholipid Syndrome
Abstract
This new edition is a comprehensive and updated resource on antiphospholipid syndrome (APS), which is an autoimmune disorder. In APS, the body recognizes certain normal components of blood and/or cell membranes as foreign substances and produces antibodies (antiphospholipid antibodies) against them. APS is associated with recurrent clotting events (thrombosis) including premature stroke, repeated miscarriages, phlebitis, venous thrombosis, and pulmonary thromboembolism. It is also associated with low platelet or blood elements that prevent bleeding. Recently, however, even more disease states have been linked with APS, including premature heart attack, various cardiac valvular abnormalities, skin lesions, kidney disease, abnormal involuntary movement/chorea, diseases that mimic multiple sclerosis, and vascular diseases of the eye that can lead to visual loss and blindness. The International Congress on Antiphospholipid Antibodies, held every 3 years, is the venue where representatives from different disciplines gather to discuss the recent advances in APS. The conference intends to cover basic aspects of APS, such as pathogenesis, origins, genetics, intracellular and molecular events, the role of infections, as well as traditional and non-traditional clinical manifestations associated with antiphospholipid antibodies. The 15th Congress took place in September 2016. A novel aspect of the Congress was that multiple teams, chaired by Scientific Planning Committee members, used evidence-based literature reviews and expert discussions to answer specific pre-defined APS-related questions. These teams included points of view from experts in rheumatology, hematology, cardiovascular medicine, obstetrics, neurology, and immunology. The Scientific Planning Committee members also chaired the congress sessions and supervised completion of the reports that are the bases of the chapters of this book. In addition, there are two chapters included specifically written for APS patients. Much like the previous volume, dedicated to the 13th International Congress on Antiphospholipid Antibodies (April 2010), this up-to-date and comprehensive work gathers invaluable insights from a multidisciplinary team of world-renowned experts and represents the authoritative resource on causes, symptoms, diagnosis, and treatment of APS.
Contents
Part I: HISTORICAL ASPECTS OF ANTIPHOSPHOLIPID SYNDROME -- History of Antiphospholipid Antibody -- Part II. BASIC SCIENCE ASPECTS OF ANTIPHOSPHOLIPID SYNDROME -- Natural Proteins Involved in Antiphospholipid Syndrome -- Origin of Antiphospholipid Antibodies -- Recent Advances in Understanding of the Genetics of Antiphospholipid Syndrome -- Mechanisms of Antiphospholipid Antibody-mediated Thrombosis -- Mechanisms of Antiphospholipid Antibody-mediated Pregnancy Morbidity -- Definition and Epidemiology of Antiphospholipid Syndrome -- Part III. CLINICAL & DIAGNOSTIC ASPECTS OF ANTIPHOSPHOLIPID SYNDROME -- Clinical and Prognostic Significance of Non-criteria Antiphospholipid Antibody Tests -- Disease and Risk Measurement Criteria in Antiphospholipid Syndrome -- Neuropsychiatric Manifestations of Antiphospholipid Syndrome -- Part IV. THERAPEUTIC ASPECTS OF ANTIPHOSPHOLIPID SYNDROME -- Prevention and Treatment of Thrombotic Antiphospholipid Syndrome -- Prevention and Treatment of Obstetric Antiphospholipid Syndrome -- Treatment of Non-criteria Manifestations in Antiphospholipid Syndrome -- Antiphospholipid Syndrome Alliance for Clinical Trials and InternatiOnal Networking (APS ACTION) -- Part V. 15th INTERNATIONAL CONGRESS ON ANTIPHOSPHOLIPID ANTIBODIES TASK FORCE REPORTS -- 15th International Congress on Antiphospholipid Antibodies - Task Force on Antiphospholipid Syndrome Classification Criteria Report -- 15th International Congress on Antiphospholipid Antibodies - Task Force on Pediatric Antiphospholipid Syndrome Report -- 15th International Congress on Antiphospholipid Antibodies - Task Force on Catastrophic Antiphospholipid Syndrome Report -- Part VI. ANTIPHOSPHOLIPID SYNDROMR FOR PATIENTS -- Antiphospholipid Syndrome: What Should Patients Know? -- Obstetric Antiphospholipid Syndrome: What Should Patients Know?
Format
e-Book
Location
Online
thumbnail

Hughes Syndrome : A Patient's Guide

http://libcat.nshealth.ca/permalink/provcat40183
Graham Hughes. (Second edition) Springer , c2016.
Available Online
View e-Book
Location
Online
This second edition is a result from a worldwide surge of interest in antiphospholipid syndrome. This disease, also known as Hughes Syndrome, affects all organs of the body including the placenta, and touches all areas of medicine. Many publications have shown that APS causes miscarriage, strokes, heart attacks and teenage epilepsy, as well as being a major, treatable cause of migraine and memory loss. Hughes' Syndrome- A Patient's Guide, Second Edition, will see many of the illustrations updat…
Available Online
View e-Book
Author
Hughes, Graham
Responsibility
Graham Hughes
Edition
Second edition
Place of Publication
Cham
Publisher
Springer
Date Published
c2016
Physical Description
1 online resource (xi, 93 p. : 22 illus., 1 illus. in color)
ISBN
9783319310282 (print ed.)
9783319310299
Subjects (MeSH)
Antiphospholipid Syndrome
Abstract
This second edition is a result from a worldwide surge of interest in antiphospholipid syndrome. This disease, also known as Hughes Syndrome, affects all organs of the body including the placenta, and touches all areas of medicine. Many publications have shown that APS causes miscarriage, strokes, heart attacks and teenage epilepsy, as well as being a major, treatable cause of migraine and memory loss. Hughes' Syndrome- A Patient's Guide, Second Edition, will see many of the illustrations updated as well as an increase in the number of figures within the chapters, to help the reader understand and treat this disease. Although labelled a 'patient's guide', the text and presentation is aimed at a wide spectrum of health care professionals.
Contents
1. Sticky Blood: the Disease Is Common -- 2. Main Clinical Features -- 3. Clotting in Veins -- 4. Stroke -- 5. Memory Loss and "Alzheimers" -- 6. Headaches, Migraine and Fits -- 7. The Spinal Cord and "Multiple Sclerosis" -- 8. The Heart and Arteries -- 9. Other Organs -- 10. The "Catastrophic" Antiphospholipid Syndrome -- 11. Pregnancy and Fetal Loss -- 12. Hughes' Syndrome and Lupus -- 13. Treatment -- 14. The Outlook -- 15. What Blood Tests Do We Use? -- 16. Research -- 17. Background -- 18. An Update -- 19. Further Reading and Websites.
Format
e-Book
Publication Type
Handbooks
Popular Works
Location
Online
thumbnail

Antiphospholipid syndrome handbook

http://libcat.nshealth.ca/permalink/provcat28091
Khamashta, M. A. Springer-Verlag , c2010.
Available Online
View e-Book
Location
Online
Available Online
View e-Book
Author
Khamashta, M. A
Other Authors
Ateka-Barrutia, Oier
Bertolaccini, Maria L
Place of Publication
London
Publisher
Springer-Verlag
Date Published
c2010
ISBN
9781846287350
Subjects (MeSH)
Antiphospholipid Syndrome
Subjects (LCSH)
Immunology
Format
e-Book
Location
Online
thumbnail

Hughes Syndrome : Antiphospholipid Syndrome

http://libcat.nshealth.ca/permalink/provcat28807
edited by M. A. Khamashta. (2nd ed.) Springer-Verlag , c2006.
Available Online
View e-Book
Location
Online
Available Online
View e-Book
Author
Khamashta, M. A
Responsibility
edited by M. A. Khamashta
Edition
2nd ed.
Place of Publication
London
Publisher
Springer-Verlag
Date Published
c2006
ISBN
9781846280092
Subjects (MeSH)
Antiphospholipid Syndrome
Subjects (LCSH)
Immunology
Format
e-Book
Location
Online
thumbnail

9 records – page 1 of 1.

Revise Search

Narrow By

   MORE