Biotargets of Cancer in Current Clinical Practice presents an updated and reasoned review of the current status of knowledge concerning the major cancer types with a special focus on the current biomarkers, genes involved and the potential future targets of innovative therapies. The volume includes for each major cancer type, a comprehensive although concise discussion of epidemiology, affirmed and innovative biomarkers for diagnosis, and descriptions of the relevant genes for prognosis and (in…
Bone metastases continue to be a major cause of morbidity in cancer patients, but improved understanding of the biology of bone metastases has led to the identification of drugs that are of potential value in not only their treatment but also their prevention. This book, written by recognized experts in the field, provides a detailed overview of current knowledge on this subject. One important focus of the book is the efficacy of bisphosphonates in preventing bone metastases in patients with br…
Prostate cancer is by far the most common cancer in men and the second leading cause of death due to cancer. It comprises a mixed group of tumours displaying varying clinical behaviour: while some have a very aggressive course, others are rather indolent. Prevention of prostate cancer and discrimination between aggressive and indolent forms are important clinical goals, and the acquisition of significant new evidence on means of achieving these aims makes this book particularly timely. A wide r…
This book gives an overview of the current knowledge on the most common neurodegenerative diseases, including Alzheimer's disease, frontotemporal lobar degeneration, amyotrophic lateral sclerosis, and additional neurodegenerative diseases. Different aspects of each disease are reviewed, including clinical issues, treatments, basic discoveries (genetics and molecular biology), and translation of basic research into biomarkers for early diagnosis. In addition, emerging data indicate that neurodeg…
This volume provides a practical, comprehensive overview on benign and malignant disease of the adult kidney. The text addresses the topic of assessment and management of patients with surgical renal disease. Within this scope, it includes hereditary and spontaneous renal neoplasms, as well as non-neoplastic disease that manifests as a clinically relevant mass. The book is organized into chapters focusing on discrete disease entities and incorporating pathology, surgical management, oncologic t…
This book provides the essential understanding needed for the assessment of patients with kidney disease. The chapters follow the sequence taken during a clinic consultation and when clerking a patient. At each stage, the principles and concepts underlying aspects of renal medicine that may seem difficult are clearly explained. Understanding Kidney Diseases includes numerous case studies and charts based upon patients' data to help students, residents and fellows develop their knowledge and ski…
An ultrasound guided percutaneous kidney biopsy is used to diagnose abnormal kidney tissue. How to get ready for a kidney biopsy, and what happens during and after the biopsy, is covered. Risks, follow up care, and symptoms requiring a visit to your family doctor or to the Emergency Department are outlined. A list of medications and how long to stop taking them both before and after the biopsy is provided.
When the kidneys are affected by some diseases, they do not work properly and can cause illness. The blood work, urine tests, and other tests such as ultrasound and renal scan can give the doctor a lot of information, but sometimes this is not enough to make the diagnosis, and a kidney biopsy is needed. From the biopsy the doctors can learn what is causing the symptoms and if treatment is required. If treatment is required, the biopsy also allows the doctor to give some idea about how seriou…
[French] On vous a dit que votre enfant a besoin d'une biopsie rénale. De nombreux parents ont des questions concernant cette procédure. Le présent document vous décrit ce qui se produit pendant et après la procédure. Le médecin et les infirmières vous expliqueront aussi la procédure et pourront répondre à toutes vos questions. / When the kidneys are affected by some diseases, they do not work properly and can cause illness. The blood work, urine tests, and other tests such as ultrasound and r…
This book combines the reference material of a nephrology textbook with the everyday relevance of a clinical handbook. This second edition develops and expands upon the success of the first. All the content has been updated and entirely new chapters on acid-base disorders and stone disease have been added. Understanding Kidney Diseases includes over 60 real-life case studies and is illustrated with over 200 figures. Readers can test their knowledge with a bank of multiple-choice questions and p…
An ultrasound guided percutaneous kidney biopsy is done to remove at least 3 tiny pieces of tissue from your kidney using a thin needle. The tissue will be sent to the lab, where it will be looked at under a microscope. Who will do the biopsy, possible complications, and how long you can expect to be at the hospital is listed. How to get ready, and what happens during and after the biopsy is covered. Follow-up care, and symptoms requiring a visit to your doctor are outlined. A list of medicatio…