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Endocrine system and selected metaboloic diseases : a compilation of paintings on the anatomy and pathophysiology of the ... / prepared by Frank H. Netter ; guest editor, Peter H. Forsham. : a compilation of paintings on the anatomy and pathophysiology of the ...

https://libcat.nshealth.ca/en/permalink/provcat14579
prepared by Frank H. Netter ; guest editor, Peter H. Forsham. --Summit, NJ: CIBA , c1965, 1970.
Call Number
WK 17 N474 v.4 1970
Location
Aberdeen Hospital
Call Number
WK 17 N474 v.4 1970
Author
Netter, Frank H. (Frank Henry), 1906-
Other Authors
Ciba Pharmaceutical Company
Responsibility
prepared by Frank H. Netter ; guest editor, Peter H. Forsham.
Place of Publication
Summit, NJ
Publisher
CIBA
Date of Publication
c1965, 1970
Physical Description
xiv, 287 p. : col. ill. ; 32 cm.
Other Subjects
Endocrinology
Metabolism
Format
Book
Location
Aberdeen Hospital
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Manual of endocrinology and metabolism

https://libcat.nshealth.ca/en/permalink/provcat21132
Lavin, Norman. (3rd ed.) --Philadelphia, PA: Lippincott Williams & Wilkins , 2002.
Call Number
WK 39 L412m 2002
Location
Dickson Building
Call Number
WK 39 L412m 2002
Author
Lavin, Norman
Edition
3rd ed.
Place of Publication
Philadelphia, PA
Publisher
Lippincott Williams & Wilkins
Date of Publication
2002
Physical Description
854 p.
ISBN
0781720141
Subjects (MeSH)
Endocrinology
Metabolism
Format
Book
Location
Dickson Building
Loan Period
3 weeks
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An introduction to behavioral endocrinology

https://libcat.nshealth.ca/en/permalink/provcat22113
Nelson, Randy J. (3rd ed.) --Sunderland, MA: Sinauer Associates , 2005.
Call Number
WK 100 N429i 2005
Location
Halifax Infirmary
Call Number
WK 100 N429i 2005
Author
Nelson, Randy J
Edition
3rd ed.
Place of Publication
Sunderland, MA
Publisher
Sinauer Associates
Date of Publication
2005
Physical Description
822 p. + 1 CD-ROM
ISBN
0878936173
Subjects (MeSH)
Endocrinology
Behavior - physiology
Format
Book
Location
Halifax Infirmary
Loan Period
3 weeks
Less detail

Endocrinology : Basic and Clinical Principles

https://libcat.nshealth.ca/en/permalink/provcat28497
edited by Shlomo Melmed, P. Michael Conn. (2nd ed.) --Totowa, NJ: Humana Press , c2005.
Available Online
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Location
Online
Available Online
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Author
Melmed, Shlomo
Other Authors
Conn, P. Michael
Responsibility
edited by Shlomo Melmed, P. Michael Conn
Edition
2nd ed.
Place of Publication
Totowa, NJ
Publisher
Humana Press
Date of Publication
c2005
ISBN
9781592598298
Subjects (MeSH)
Endocrinology
Hormones
Subjects (LCSH)
Endocrinology 
Format
e-Book
Location
Online
Less detail

Evidence-Based Endocrinology

https://libcat.nshealth.ca/en/permalink/provcat29012
edited by Victor M. Montori. --Totowa, NJ: Mayo Foundation for Medical Education and Research , c2006.
Available Online
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Location
Online
Available Online
View e-Book
Author
Montori, Victor M
Responsibility
edited by Victor M. Montori
Place of Publication
Totowa, NJ
Publisher
Mayo Foundation for Medical Education and Research
Date of Publication
c2006
Series Title
Contemporary endocrinology (Totowa, N.J.)
ISBN
9781597450089
Subjects (MeSH)
Endocrine System Diseases
Endocrinology
Evidence-Based Medicine
Subjects (LCSH)
Endocrinology 
Format
e-Book
Location
Online
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A Time for Metabolism and Hormones

https://libcat.nshealth.ca/en/permalink/provcat43932
Paolo Sassone-Corsi, Yves Christen, editors. --Cham: SpringerOpen , c2016.
Available Online
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Access
Open access
Location
Online
Recent years have seen spectacular advances in the field of circadian biology. These have attracted the interest of researchers in many fields, including endocrinology, neurosciences, cancer, and behavior. By integrating a circadian view within the fields of endocrinology and metabolism, researchers will be able to reveal many, yet-unsuspected aspects of how organisms cope with changes in the environment and subsequent control of homeostasis. This field is opening new avenues in our understandi…
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Other Authors
Sassone-Corsi, Paolo
Christen, Yves
Responsibility
Paolo Sassone-Corsi, Yves Christen, editors
Place of Publication
Cham
Publisher
SpringerOpen
Date of Publication
c2016
Physical Description
1 online resource (xiii, 132 p.) : 28 illus., 26 illus. in color.
Series Title
Research and perspectives in endocrine interactions
ISBN
9783319270692
9783319270685 (Print ed.)
9783319270708 (Print ed.)
9783319800677 (Print ed.)
ISSN
1861-2253
Subjects (MeSH)
Circadian Clocks - physiology
Circadian rhythm - physiology
Metabolism - physiology
Specialty
Endocrinology
Physiology
Abstract
Recent years have seen spectacular advances in the field of circadian biology. These have attracted the interest of researchers in many fields, including endocrinology, neurosciences, cancer, and behavior. By integrating a circadian view within the fields of endocrinology and metabolism, researchers will be able to reveal many, yet-unsuspected aspects of how organisms cope with changes in the environment and subsequent control of homeostasis. This field is opening new avenues in our understanding of metabolism and endocrinology. A panel of the most distinguished investigators in the field gathered together to discuss the present state and the future of the field. The editors trust that this volume will be of use to those colleagues who will be picking up the challenge to unravel how the circadian clock can be targeted for the future development of specific pharmacological strategies toward a number of pathologies.
Contents
The epigenetic and metabolic language of the circadian clock -- Molecular architecture of the circadian clock in mammals -- Circadian mechanisms in bioenergetics and cell metabolism -- Control of metabolism by central and peripheral clocks in Drosophila -- Circadian post-transcriptional control of metabolism -- Redox and metabolic oscillations in the clockwork -- Rev-erbs: integrating metabolism around the clock -- Control of sleep-wake cycles in Drosophila -- Circadian metabolomics: insights for biology and medicine -- Rhythms within rhythms: the importance of oscillations for glucocorticoid hormones -- The genetics of autism spectrum disorders.
Access
Open access
Format
e-Book
Location
Online
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Stem Cells in Neuroendocrinology

https://libcat.nshealth.ca/en/permalink/provcat43934
Donald Pfaff, Yves Christen, editors. --Cham: SpringerOpen , c2016.
Available Online
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Access
Open access
Location
Online
This volume starts with an elementary introduction covering stem cell methodologies used to produce specific types of neurons, possibilities for their therapeutic use, and warnings of technical problems. In addition the authors report successes in achieving the derivation of a specific type of neuron. The dopamine neuron offers an important example and is discussed in more detail. Additional chapters cover problems obviously approachable with cells derived from stem cells, including their need …
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Other Authors
Pfaff, Donald W., 1939-
Christen, Yves
Responsibility
Donald Pfaff, Yves Christen, editors
Place of Publication
Cham
Publisher
SpringerOpen
Date of Publication
c2016
Physical Description
1 online resource (xii, 156 p.) : 16 illus. in color
Series Title
Research and perspectives in endocrine interactions
ISBN
9783319416038
9783319416021 (Print ed.)
9783319416045 (Print ed.)
9783319823942 (Print ed.)
ISSN
1861-2253
Subjects (MeSH)
Neural Stem Cells - cytology
Neurosecretory Systems - anatomy & histology
Specialty
Endocrinology
Neurology
Transplantation
Abstract
This volume starts with an elementary introduction covering stem cell methodologies used to produce specific types of neurons, possibilities for their therapeutic use, and warnings of technical problems. In addition the authors report successes in achieving the derivation of a specific type of neuron. The dopamine neuron offers an important example and is discussed in more detail. Additional chapters cover problems obviously approachable with cells derived from stem cells, including their need in surgeries for pituitary cancers. The last chapter provides an overview of this particular field of research and presents a vision for its future directions.
Contents
A brief overview of techniques for modulating neuroendocrine and other neural systems -- Basics of stem cell biology as applied to the brain -- Human pluripotent-derived lineages for repairing hypopituitarism -- Recapitulating hypothalamus and pituitary development using ES/iPS cells -- Regulation of body weight and metabolism by tanycyte-derived neurogenesis in young adult mice -- Genetic dissection of the neuroendocrine and behavioral responses to stressful challenges -- Pituitary stem cells: quest for hidden functions -- Pituitary stem cells during normal physiology and disease -- Epigenetic mechanisms of pituitary cell fate specification -- Advances in stem cells biology: new approaches to understand depression -- Perspective on stem cells in developmental biology, with special reference to neuroendocrine systems.
Access
Open access
Format
e-Book
Location
Online
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Endocrinology of the Testis and Male Reproduction

https://libcat.nshealth.ca/en/permalink/provcat41522
Manuela Simoni, Ilpo T. Huhtaniemi, editors. --Cham: Springer , c2017.
Available Online
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Location
Online
This book provides a comprehensive overview of endocrinology of the male reproductive system, explaining how it works and how, sometimes, it fails to work. World-class specialists present state of the art knowledge on all aspects, including anatomy, physiology, molecular biology, genetics, pathophysiology, clinical manifestations of testicular diseases, endocrine aspects of andrological and sexual diseases, and therapy. Extensive consideration is given to sexual development, testicular function…
Available Online
View e-Book
Other Authors
Simoni, Manuela
Huhtaniemi, Ilpo T.
Responsibility
Manuela Simoni, Ilpo T. Huhtaniemi, editors
Place of Publication
Cham
Publisher
Springer
Date of Publication
c2017
Physical Description
1 online resource (xxii, 1364 pages) : 127 illus., 103 illus. in color
Series Vol.
1
Series Title
Springer reference
Endocrinology
ISBN
9783319444413
9783319444406 (print ed.)
ISSN
2510-1927
Subjects (MeSH)
Andrology
Endocrinology
Male
Infertility, male
Reproductive Health
Reproductive Physiological Phenomena
Testis - physiology
Notes
"eReference"--Publisher.
Abstract
This book provides a comprehensive overview of endocrinology of the male reproductive system, explaining how it works and how, sometimes, it fails to work. World-class specialists present state of the art knowledge on all aspects, including anatomy, physiology, molecular biology, genetics, pathophysiology, clinical manifestations of testicular diseases, endocrine aspects of andrological and sexual diseases, and therapy. Extensive consideration is given to sexual development, testicular function, the clinical approach to disorders of male reproduction, male hypogonadism, sexual dysfunction, and male infertility. In addition, sociodemographic, psychological, and ethical aspects of male reproductive disorders are discussed. The book is intended as a major reference for endocrinologists, andrologists, and sexologists, as well as basic and clinical scientists. It is published as part of the SpringerReference program, which delivers access to living editions constantly updated through a dynamic peer-review publishing process.
Contents
GnRH Action -- Sex Determination -- Testicular Steroidogenesis and Testosterone -- Testis Development and Descent -- Anamnesis and Physical Examination -- The Semen Analysis -- Primary and Secondary Hypogonadism -- Gynecomastia -- Genetics of Male Infertility -- Varicocele -- Assisted Reporduction for Male Infertility -- Male Contraception -- Use, Misuse and Abuse of Androgens -- Ethical Aspects of Male Reproductive Disorders and Their Treatment.
Format
e-Book
Location
Online
Less detail

Hormones, Metabolism and the Benefits of Exercise

https://libcat.nshealth.ca/en/permalink/provcat43933
Bruce Spiegelman, editor. --Cham: SpringerOpen , c2017.
Available Online
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Access
Open access
Location
Online
The world is faced with an epidemic of metabolic diseases such as obesity and type 2 diabetes. This is due to changes in dietary habits and the decrease in physical activity. Exercise is usually part of the prescription, the first line of defense, to prevent or treat metabolic disorders. However, we are still learning how and why exercise provides metabolic benefits in human health. This open access volume focuses on the cellular and molecular pathways that link exercise, muscle biology, hormon…
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Other Authors
Spiegelman, Bruce M.
Other Authors
Fondation IPSEN pour la recherche thérapeutique
Responsibility
Bruce Spiegelman, editor
Place of Publication
Cham
Publisher
SpringerOpen
Date of Publication
c2017
Physical Description
1 online resource (x, 102 p.) : ill. (some col.)
Series Title
Research and perspectives in endocrine interactions
ISBN
9783319727905
9783319727899 (Print ed.)
9783319727912 (Print ed.)
9783030102685 (Print ed.)
ISSN
1861-2253
Subjects (MeSH)
Exercise - physiology
Hormones - physiology
Metabolism - physiology
Specialty
Biochemistry
Endocrinology
Physiology
Abstract
The world is faced with an epidemic of metabolic diseases such as obesity and type 2 diabetes. This is due to changes in dietary habits and the decrease in physical activity. Exercise is usually part of the prescription, the first line of defense, to prevent or treat metabolic disorders. However, we are still learning how and why exercise provides metabolic benefits in human health. This open access volume focuses on the cellular and molecular pathways that link exercise, muscle biology, hormones and metabolism. This will include novel “myokines” that might act as new therapeutic agents in the future.
Contents
Human brown adipose tissue plasticity: hormonal and environmental manipulation -- The energy sensor AMPK: adaptations to exercise, nutritional and hormonal signals -- Plasma steroids and cardiorespiratory fitness response to regular exercise -- Sending the signal: muscle glycogen availability as a regulator of training adaptation -- Optimized engagement of macrophages and satellite cells in the repair and regeneration of exercised muscle -- Skeletal muscle microRNAs: roles in differentiation, disease and exercise -- Tryptophan-kynurenine metabolites in exercise and mental health -- The role of FNDC5/irisin in the nervous system and as a mediator for beneficial effects of exercise on the brain.
Access
Open access
Format
e-Book
Location
Online
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Principles of Endocrinology and Hormone Action

https://libcat.nshealth.ca/en/permalink/provcat44562
edited by Antonino Belfiore, Derek LeRoith. --Cham: Springer , c2017.
Available Online
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Location
Online
This volume provides comprehensive coverage of the current knowledge of the physiology of the endocrine system and hormone synthesis and release, transport, and action at the molecular and cellular levels. It presents essential as well as in-depth information of value to both medical students and specialists in Endocrinology, Gynecology, Pediatrics, and Internal Medicine. Although it is well established that the endocrine system regulates essential functions involved in growth, reproduction, an…
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Other Authors
Belfiore, Antonino
LeRoith, Derek
Responsibility
edited by Antonino Belfiore, Derek LeRoith
Place of Publication
Cham
Publisher
Springer
Date of Publication
c2017
Physical Description
1 online resource
Series Title
Springer reference
Endocrinology
ISBN
9783319273181
ISSN
2510-1927
Subjects (MeSH)
Endocrine System - physiology
Hormones - metabolism
Specialty
Endocrinology
Notes
"Living reference work."
Abstract
This volume provides comprehensive coverage of the current knowledge of the physiology of the endocrine system and hormone synthesis and release, transport, and action at the molecular and cellular levels. It presents essential as well as in-depth information of value to both medical students and specialists in Endocrinology, Gynecology, Pediatrics, and Internal Medicine. Although it is well established that the endocrine system regulates essential functions involved in growth, reproduction, and homeostasis, it is increasingly being recognized that this complex regulatory system comprises not only hormones secreted by the classic endocrine glands but also hormones and regulatory factors produced by many organs, and involves extensive crosstalk with the neural and immune system. At the same time, our knowledge of the molecular basis of hormone action has greatly improved. Understanding this complexity of endocrine physiology is crucial to prevent endocrine disorders, to improve the sensitivity of our diagnostic tools, and to provide the rationale for pharmacological, immunological, or genetic interventions. It is such understanding that this book is designed to foster.
Contents
Cytokine Receptors -- Endocrine Functions of Bone -- G Protein-Coupled Receptors -- Genetic Disorders of Adrenocortical Function -- Growth Hormones and Aging -- Molecular Mechanisms of Thyroid Hormone Synthesis and Secretion -- Nongenomic Actions of Thyroid Hormones -- Ovarian Physiology -- Steroid Hormone Receptors and Signal Transduction Processes -- Principles of Endocrine Diseases -- Receptor Tyrosine Kinases and the Insulin Signaling System -- Steroid Hormones: Synthesis, Secretion, and Transport -- Synthesis, Secretion and Transport of Peptide Hormones -- Targeting of Steroid Hormone Receptor Function in Breast and Prostate Cancer -- The Adrenal Glands -- The Endocrine Control of Human Pregnancy -- The Endocrine Gut -- The Endocrine Heart -- The Endocrine Pancreas -- The Endocrine Regulation of Blood Pressure -- The Endocrine Regulation of Energy and Body Weight -- The Endocrine System -- The Endocrinology of Puberty -- The Hypothalamus–Pituitary Axis -- The Parathyroids -- The Physiology of the Testis -- The Posterior Pituitary -- The Thyroid -- Thyroid Hormone Nuclear Receptors and Molecular Actions.
Format
e-Book
Location
Online
Less detail

Endocrinology of the Testis and Male Reproduction

https://libcat.nshealth.ca/en/permalink/provcat44566
edited by Manuela Simoni, Ilpo Huhtaniemi. --Cham: Springer , c2017.
Available Online
View e-Book
Location
Online
This book provides a comprehensive overview of endocrinology of the male reproductive system, explaining how it works and how, sometimes, it fails to work. World-class specialists present state of the art knowledge on all aspects, including anatomy, physiology, molecular biology, genetics, pathophysiology, clinical manifestations of testicular diseases, endocrine aspects of andrological and sexual diseases, and therapy. Extensive consideration is given to sexual development, testicular function…
Available Online
View e-Book
Other Authors
Simoni, Manuela
Huhtaniemi, Ilpo
Responsibility
edited by Manuela Simoni, Ilpo Huhtaniemi
Place of Publication
Cham
Publisher
Springer
Date of Publication
c2017
Physical Description
1 online resource
Series Title
Springer reference
Endocrinology
ISBN
9783319294568
ISSN
2510-1927
Subjects (MeSH)
Andrology
Endocrine System
Infertility, Male
Reproductive Medicine
Reproductive Physiological Phenomena
Testis - physiology
Specialty
Endocrinology
Men's Health
Reproductive Medicine
Notes
"Living reference work."
Abstract
This book provides a comprehensive overview of endocrinology of the male reproductive system, explaining how it works and how, sometimes, it fails to work. World-class specialists present state of the art knowledge on all aspects, including anatomy, physiology, molecular biology, genetics, pathophysiology, clinical manifestations of testicular diseases, endocrine aspects of andrological and sexual diseases, and therapy. Extensive consideration is given to sexual development, testicular function, the clinical approach to disorders of male reproduction, male hypogonadism, sexual dysfunction, and male infertility. In addition, sociodemographic, psychological, and ethical aspects of male reproductive disorders are discussed. The book is intended as a major reference for endocrinologists, andrologists, and sexologists, as well as basic and clinical scientists. It is published as part of the SpringerReference program, which delivers access to living editions constantly updated through a dynamic peer-review publishing process.
Contents
Anabolic and Metabolic Effects of Testosterone and Other Androgens: Direct Effects and Role of Testosterone Metabolic Products -- Anamnesis and Physical Examination -- Androgen Receptor -- Androgen Resistance -- Assisted Reproduction for Male Infertility -- Classification and Epidemiology of Hypogonadism -- Clinical Manifestation and Diagnosis of Androgen Deficiency -- Color-Doppler Ultrasound and New Imaging Techniques in Andrological Examination -- Control of GnRH Secretion -- Cryopreservation of Spermatozoa -- Delayed Puberty -- Effect of Cancer Treatments on Testicular Function -- Endocrinology of the Fetal Testis -- Epididymal Sperm Transport and Fertilization -- Estrogen Deficiency in Men -- Ethical Aspects of Male Reproductive Disorders and their Treatment -- Functional Anatomy and Histology of the Testis -- Genetic Analysis in Male Infertility -- Genetics of Male Infertility -- GnRH Action -- Gonadotrophin Receptors -- Gonadotropins -- Gynecomastia -- Histopathological Evaluation of Testicular Biopsy -- Hormonal Laboratory Examination -- Hormonal Treatment of Male Infertility: Gonadotropins and Beyond -- Hypogonadism in Systemic Diseases -- Infectious and Immunological Aspects of Male Infertility -- Intra-Testicular Sperm Extraction -- Late-Onset Hypogonadism -- Male Contraception -- Male Sexual Differentiation -- Nonhormonal Medical Treatment of Male Infertility -- Pre-Testicular, Testicular, and Post-Testicular Causes of Male Infertility -- Primary and Secondary Hypogonadism -- Psychological Aspects of Infertility Among Men -- Sex Determination -- Spermatogenesis -- Testicular Steroidogenesis -- Testis Development and Descent -- The Semen Analysis: The Investigation of the Human Ejaculate -- Therapy with Anti-androgens in Gender Dysphoric Natal Males -- Treatment of Hypogonadism -- Use, Misuse, and Abuse of Androgens -- Varicocele.
Format
e-Book
Location
Online
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Hypothalamic-Pituitary Diseases

https://libcat.nshealth.ca/en/permalink/provcat44568
edited by Felipe F. Casanueva, Ezio Ghigo. --Cham: Springer , c2017.
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Location
Online
This book presents the state of the art in the pathophysiology, diagnosis, and therapy of hypothalamic and pituitary disorders. After an introduction devoted to the physiology of the neuroendocrine control of the hypothalamic-pituitary unit, the diverse disorders involving hormonal excess or deficiency are systematically addressed axis by axis. For each disorder, pathophysiology, clinical presentation, and management are discussed in detail. In addition, individual chapters focus on the neuroen…
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Other Authors
Casanueva, Felipe F.
Ghigo, Ezio
Responsibility
edited by Felipe F. Casanueva, Ezio Ghigo
Place of Publication
Cham
Publisher
Springer
Date of Publication
c2017
Physical Description
1 online resource (x, 530 p.)
Series Title
Springer reference
Endocrinology
ISBN
9783319386812
ISSN
2510-1927
Subjects (MeSH)
Hypothalamic Diseases
Pituitary Diseases
Specialty
Endocrinology
Notes
"Living reference work."
Abstract
This book presents the state of the art in the pathophysiology, diagnosis, and therapy of hypothalamic and pituitary disorders. After an introduction devoted to the physiology of the neuroendocrine control of the hypothalamic-pituitary unit, the diverse disorders involving hormonal excess or deficiency are systematically addressed axis by axis. For each disorder, pathophysiology, clinical presentation, and management are discussed in detail. In addition, individual chapters focus on the neuroendocrinology of energy homeostasis and of bone metabolism, metabolic derangement secondary to pituitary dysfunction, and pituitary control of the endocrine pancreas. While the focus of the book is predominantly on pathophysiological and clinical aspects, due attention is also devoted to potential diagnostic and therapeutic innovations. The book is intended as a major reference for endocrinologists and basic and clinical scientists.
Contents
Central Hypogonadism in the Male: Physiopathology, Diagnosis and Treatment -- Craniopharyngioma and Posttreatment Pituitary Dysfunction in Brain Tumors -- Neuroendocrine Control of Carbohydrate Metabolism -- Neuroendocrinology of Bone Metabolism -- Neuroendocrinology of Energy Homeostasis -- Physiology of the Hypothalamus Pituitary Unit -- Physiopathology, Diagnosis and Treatment of Inappropriate ADH Secretion and Cerebral Salt Wasting Syndrome -- Physiopathology, Diagnosis and Treatment of Secondary Hyperthyroidism -- Physiopathology, Diagnosis, and Treatment of Diabetes Insipidus -- Physiopathology, Diagnosis, and Treatment of Functional Pituitary Dysfunction -- Physiopathology, Diagnosis, and Treatment of GH Deficiency -- Physiopathology, Diagnosis, and Treatment of GH Hypersecretion -- Physiopathology, Diagnosis, and Treatment of Hypercortisolism -- Physiopathology, Diagnosis, and Treatment of Hyperprolactinemia -- Physiopathology, Diagnosis, and Treatment of Nonfunctioning Pituitary Adenomas -- Physiopathology, Diagnosis, and Treatment of Secondary Female Hypogonadism -- Physiopathology, Diagnosis, and Treatment of Secondary Hypothyroidism.
Format
e-Book
Location
Online
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Textbook of nephro-endocrinology

https://libcat.nshealth.ca/en/permalink/provcat31385
edited by Ajay K. Singh, Gordon H. Williams. (2nd ed.) --London, UK: Elsevier , c2018.
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Location
Online
Textbook of Nephro-Endocrinology, Second Edition, continues to be the definitive translational reference in the field of nephro-endocrinology, investigating both the endocrine functions of the kidneys and how the kidney acts as a target for hormones from other organ systems. It offers researchers and clinicians expert analyses of nephro-endocrine research and translation into the treatment of diseases such as anemia, chronic kidney disease (CKD), rickets, osteoporosis, and hypoparathyroidism.
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Other Authors
Singh, Ajay
Williams, Gordon H
Responsibility
edited by Ajay K. Singh, Gordon H. Williams
Edition
2nd ed.
Alternate Title
Nephro-endocrinology
Place of Publication
London, UK
Publisher
Elsevier
Date of Publication
c2018
Physical Description
1 online resource, 584 p.
ISBN
9780128032473
Subjects (MeSH)
Kidney Diseases - physiopathology
Kidney Diseases - complications
Endocrine System Diseases - physiopathology
Hormones - metabolism
Subjects (LCSH)
Kidneys - Diseases - Endocrine aspects
Kidney Diseases - physiopathology
Kidney Diseases - complications
Endocrine System Diseases - etiology
Hormones - metabolism
Specialty
Endocrinology
Nephrology
Abstract
Textbook of Nephro-Endocrinology, Second Edition, continues to be the definitive translational reference in the field of nephro-endocrinology, investigating both the endocrine functions of the kidneys and how the kidney acts as a target for hormones from other organ systems. It offers researchers and clinicians expert analyses of nephro-endocrine research and translation into the treatment of diseases such as anemia, chronic kidney disease (CKD), rickets, osteoporosis, and hypoparathyroidism.
Access
Registration required for PDF access.
Format
e-Book
Location
Online
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Thyroid Diseases : Pathogenesis, Diagnosis, and Treatment

https://libcat.nshealth.ca/en/permalink/provcat42579
Paolo Vitti, Laszlo Hegedüs, editors. --Cham: Springer , c2018.
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Location
Online
This book presents the latest advances in knowledge of the pathogenesis of thyroid diseases and describes the state of the art in their diagnosis and treatment, including newly emerging management approaches. After an opening section that addresses thyroid physiology and laboratory evaluation, each of the major thyroid diseases and their subtypes is discussed, covering goiter and thyroid nodule, thyroiditis, hypothyroidism, hyperthyroidism and thyrotoxicosis, and thyroid carcinoma. Other condit…
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Other Authors
Vitti, Paolo
Hegedüs, Laszlo
Responsibility
Paolo Vitti, Laszlo Hegedüs, editors
Place of Publication
Cham
Publisher
Springer
Date of Publication
c2018
Physical Description
1 online resource (xviii, 770 p.) : 117 illus., 78 illus. in color
Series Title
Springer reference
Endocrinology
ISBN
9783319450131
9783319450124 (print ed.)
ISSN
2510-1927
Subjects (MeSH)
Thyroid Diseases
Thyroid Neoplasms
Specialty
Endocrinology
Notes
"eReference"--Publisher.
Abstract
This book presents the latest advances in knowledge of the pathogenesis of thyroid diseases and describes the state of the art in their diagnosis and treatment, including newly emerging management approaches. After an opening section that addresses thyroid physiology and laboratory evaluation, each of the major thyroid diseases and their subtypes is discussed, covering goiter and thyroid nodule, thyroiditis, hypothyroidism, hyperthyroidism and thyrotoxicosis, and thyroid carcinoma. Other conditions that affect thyroid function or induce thyroid dysfunction are also considered, e.g., pregnancy, non-thyroidal disorders, and medication use. The book is designed to assist practitioners to achieve optimal outcomes in clinical routine by providing clear guidance on clinical examination, the use of diagnostic tests, first- and second-line therapies, and follow-up. Chapter have been written by recognized experts in the field.
Contents
Part I. Thyroid physiology and laboratory evaluation of the thyroid: Regulation of thyroid function, synthesis and function of thyroid hormones -- Tests of thyroid function -- Thyroid autoantibodies -- Thyroid imaging -- Part II. Goiter and thyroid nodule: Non-toxic goiter -- Thyroid nodule -- Part III. Thyroiditis: Hashimoto's thyroiditis -- Post-partum thyroiditis and silent thyroiditis -- Acute and sub-acute thyroiditis -- Part IV. Hypothyroidism: Classification and etiopathogenesis -- Congenital hypothyroidism -- Primary hypothyroidism -- Central hypothyroidism -- Diagnosis and treatment of hypothyroidism -- Part V. Hyperthyroidism and thyrotoxicosis: Graves' disease -- Graves' ophthalmopathy -- Treatment of Graves' disease -- Toxic adenoma and multinodular toxic goiter -- Other forms of thyrotoxicosis -- Part VI. Thyroid carcinoma: Pathogenesis of thyroid carcinoma -- Differentiated thyroid carcinoma of follicular origin -- Medullary carcinoma -- Anaplastic and other forms of thyroid carcinoma -- New (medical) treatment for thyroid carcinoma -- Part VII. Other conditions influencing thyroid function or inducing thyroid dysfunction: Thyroid physiology and thyroid diseases in pregnancy -- Non-thyroidal illness -- Drugs and other substances interfering with thyroid function and inducing thyroid diseases.
Format
e-Book
Location
Online
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Practical Management of Thyroid Cancer : A Multidisciplinary Approach

https://libcat.nshealth.ca/en/permalink/provcat42585
Ujjal K. Mallick, Clive Harmer, editors. (Second edition) --Cham: Springer , c2018.
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Online
The new edition of this book highlights the recent advances and state-of-the art in surgical and non-surgical management of thyroid cancer. Readers will learn about the latest advances and recommendations in the field, from molecular studies and biomarkers to the changing epidemiology, kinase inhibition in drug discovery and new surgical approaches, such as intra-operative neural monitoring and robotics. The management of differentiated thyroid cancer as well as childhood cancer, survivorship a…
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Other Authors
Mallick, Ujjal K.
Harmer, Clive
Responsibility
Ujjal K. Mallick, Clive Harmer, editors
Edition
Second edition
Place of Publication
Cham
Publisher
Springer
Date of Publication
c2018
Physical Description
1 online resource (xvi, 395 p.) : 79 illus., 30 illus. in color
ISBN
9783319917252
9783319917245 (print ed.)
9783319917269 (print ed.)
Subjects (MeSH)
Patient Care Team
Thyroid Neoplasms - therapy
Specialty
Endocrinology
Abstract
The new edition of this book highlights the recent advances and state-of-the art in surgical and non-surgical management of thyroid cancer. Readers will learn about the latest advances and recommendations in the field, from molecular studies and biomarkers to the changing epidemiology, kinase inhibition in drug discovery and new surgical approaches, such as intra-operative neural monitoring and robotics. The management of differentiated thyroid cancer as well as childhood cancer, survivorship and clinical trial design and findings and how these fit into cancer management are discussed in detail. This comprehensive volume provides an overview of the current world literature and outlines the practical aspects of management from world leaders in this field and helps clinicians and patients on practical matters. With a selection of authors from around the world it draws on international experience giving a global perspective to the topic. Following on from the success of the first edition, it uses a multidisciplinary, evidence-based approach centered on the patient, discussing guidelines and how these have improved the quality of care and outcomes. This guide is aimed mainly at thyroidologists of all disciplines, (in training or experts) students, non-specialist clinicians, nursing staff, all the disciplines involved in a multidisciplinary team such as surgeons—Head & Neck or Endocrine and General Surgeons, Oncologists, Endocrinologists, Nuclear Medicine Physicians, Nuclear Medicine Physicists, Radiologists, Pathologists, Specialist Nurses, Geneticists, Clinical Psychologists, Palliative Care Physicians and, of course, patients.
Contents
1. Pragmatism, Precision Oncology, International Partnership for Research and Quality-The New Paradigm for Thyroid Cancer -- Part I. Multidisciplinary Approach to Management of Thyroid Cancer -- 2. The UK Evidence-Based Guidelines for the Management of Thyroid Cancer: Key Recommendations -- 3. The 2015 American Thyroid Association Evidence-Based Guidelines for Management of Patients with Thyroid Nodules and Differentiated Thyroid Cancer: Key Recommendations -- 4. Thyroid Cancer: One Doctor-Patient Partnership -The Newcastle Butterfly Model -- Part II. The Diagnosis of Thyroid Cancer -- 5. Molecular Diagnosis of Thyroid Nodules -- 6. Ultrasonography in Diagnosis and Management of Thyroid Cancer ÇôCurrent International Recommendations -- Part III. Initial Thyroid Surgery -- 7. The 21st Century Endocrine Surgeon -- 8. Management of Cervical Lymph Nodes in Differentiated Thyroid Cancer -- 9. Advances in Thyroid Surgery -- Part IV. Non surgical Management of Differentiated Thyroid Cancer -- 10. Risk Stratification and Current Management of Low Risk Thyroid Cancer -- 11. Management of Low risk Papillary Thyroid Carcinomo and Papillary Cancer and Microcarcinoma-the Japanese experience -- 12. Radioiodine Ablation—Current Status -- 13. Dosimetric Approaches—Current Concepts -- 14. External Radiation in Differentiated Thyroid Cancer in the era of IMRT and modern radiation planning techniques -- Part V. Follow up and Longterm Management of Differentiated Thyroid Cancer -- 15. Thyroglobulin -- 16. Management of Post-Operative Hypocalcemia -- 17. Radioiodine Refractory Thyroid Cancer -- Part VI. Medullary Thyroid Carcinoma -- 18. Medullary Thyroid Cancer :Surgical Management -- 19. Medullary Thyroid Cancer: Diagnosis and Non Surgical Management -- 20. Familial Non-Medullary Thyroid Cancer -- Part VII. Thyroid Cancer in Children -- 21. Pediatric Differentiated Thyroid Carcinoma -- Part VIII. Aggressive Thyroid Cancers -- 22. Anaplastic Thyroid Cancer -- 23. Palliative care -- Part IX. Future Developments and Directions for Research in Thyroid Cancer -- 24. Translational Research and Genomics Driven Trials in Thyroid Cancer -- 25. Thyroid Cancer Trials -- 26. The Barriers to Uniform Implementation of Clinical Practice Guidelines (CPG) for Thyroid Cancer -- 27. Survivorship: The Role of the Clinical Psychologist and the Clinical Nurse Specialist in Thyroid Cancer Care.
Format
e-Book
Location
Online
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Difficult Decisions in Endocrine Surgery : An Evidence-Based Approach

https://libcat.nshealth.ca/en/permalink/provcat42705
Peter Angelos, Raymon H. Grogan, editors. --Cham: Springer , c2018.
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This book provides a comprehensive overview of difficult decisions encountered within endocrine surgery. Brief uniformly formatted chapters are devoted to answering specific questions relevant to a range of topics across endocrine surgery based upon detailed analysis of available evidence.Topics covered include clinical decision analysis, decision making from the surgeon's and patient's perspective, using surgery as opposed to observation for papillary thyroid microcarcinoma, and the use of par…
Available Online
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Other Authors
Angelos, Peter
Grogan, Raymon H.
Responsibility
Peter Angelos, Raymon H. Grogan, editors
Place of Publication
Cham
Publisher
Springer
Date of Publication
c2018
Physical Description
1 online resource (xxviii, 483 p.) : 28 illus., 15 illus. in color
Series
Difficult decisions in surgery: an evidence-based approach
Series Title
Difficult decisions in surgery
ISBN
9783319928609
9783319928586 (print ed.)
9783319928593 (print ed.)
ISSN
2198-7750
Subjects (MeSH)
Clinical Decision-Making
Endocrine Gland Neoplasms - surgery
Endocrine Surgical Procedures
Specialty
Clinical Decision-Making
Endocrinology
Surgical Procedures, Operative
Abstract
This book provides a comprehensive overview of difficult decisions encountered within endocrine surgery. Brief uniformly formatted chapters are devoted to answering specific questions relevant to a range of topics across endocrine surgery based upon detailed analysis of available evidence.Topics covered include clinical decision analysis, decision making from the surgeon's and patient's perspective, using surgery as opposed to observation for papillary thyroid microcarcinoma, and the use of parathyroid cryopreservation. Difficult Decisions in Endocrine Surgery: An Evidence-Based Approach features a wealth of information on ideal approaches for making clinical decisions in selected clinical situations. It is an important and timely resource for all endocrine surgical trainees, fellows, practitioners, educators, and healthcare providers involved in the management of these patients.
Contents
Evidence-based Medicine and the GRADE Approach -- Clinical Decision Analysis -- Decision Making from the Surgeon's Perspective -- Decision Making from the Patient's Perspective -- Surgery Versus Active Surveillance for Papillary Thyroid Microcarcinoma -- Prospective Screening Protocol for FNMTC Family Members: Ultrasound Versus Physical Examination -- Operative Management Versus Observation for Thyroid Nodules Larger than 4 cm with Benign Cytology -- Lobectomy Versus Total Thyroidectomy for Follicular Microcarcinomas -- Initial Total Thyroidectomy Versus Lobectomy with Intraoperative Frozen Section for Thyroid Nodules that are "Suspicious for PTC" -- Primary Repair Versus No Repair for Transected Recurrent Laryngeal Nerve -- Surgery Versus Observation for Papillary Thyroid Microcarcinoma -- First-line Therapy for Anaplastic Thyroid Cancer: Operation Versus Medical Management -- Same-Day Versus Overnight Inpatient Surgery for Total Thyroidectomy -- Prophylactic Versus Selective Central Neck Dissection in Pediatric Papillary Thyroid Cancer -- Subtotal Parathyroidectomy Versus Total Parathyroidectomy with Autotransplantation for Patients with MEN-1 and Primary Hyperparathyroidism -- Four-Gland Exploration versus 4D Computed Tomography in Patients with Nonlocalized Primary Hyperparathyroidism -- Lymph Node Dissection Versus No Lymph Node Dissection for Parathyroid Cancer -- Early Versus Late Parathyroidectomy for Tertiary (Posttransplant) Hyperparathyroidism -- Observation Versus Surgery for Pregnant Patients with Primary Hyperparathyroidism -- Four-gland Exploration Versus Focused Parathyroidectomy for Hyperparathyroidism Jaw Tumor Syndrome -- Long-Term Success of Surgery for Primary Hyperparathyroidism: Intraoperative Parathyroid Hormone Versus Four-Gland Exploration -- The Evidence For and Against Parathyroid Cryopreservation: Should We Continue to Promote Parathyroid Cryopreservation? -- Should Antibiotic Prophylaxis Be Given Prior to Thyroidectomy or Parathyroidectomy? -- The Value of Intraoperative Parathyroid Hormone Monitoring in Primary Hyperparathyroidism Cases that are Localized -- Transperitoneal Versus Retroperitoneal Laparoscopic Adrenalectomy -- Bilateral Adrenalectomy Versus Medical Management for Cushing's Syndrome with Bilateral Adrenal Hyperplasia -- Routine Screening for Primary Hyperaldosteronism in Hypertensive Patients: Yes or No? -- Routine Glucose Monitoring in Postoperative Pheochromocytoma Patients: Yes or No? -- Surgical Versus Nonsurgical Management of Malignant Pheochromocytoma -- Alpha Blocker Versus Calcium Channel Blocker for Pheochromocytoma -- Surgical Versus Nonsurgical Therapy for Recurrent Adrenocortical Carcinoma -- Resection Versus Observation for Adrenal Gland Metastasis -- Routine Versus Selective Adrenal Vein Sampling for Primary Aldosteronism -- Surgery Versus Observation for Asymptomatic Nonfunctioning Pancreatic Neuroendocrine Tumors -- Routine Lymph Node Dissection Versus Duodenal Inspection Alone for the Treatment of Multiple Endocrine Neoplasia Type 1 Patients with Hypergastrinemia -- Resection Versus Chemotherapy for Metastatic Neuroendocrine Tumors of the Pancreas -- Observation Versus Surgery for Nonlocalized Insulinoma. .
Format
e-Book
Location
Online
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Pituitary Tumors : A Clinical Casebook

https://libcat.nshealth.ca/en/permalink/provcat42723
Lisa B. Nachtigall, editor. --Cham: Springer , c2018.
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Location
Online
Comprised of cases presenting diverse clinical scenarios involving pituitary tumors and related conditions, this concise, practical casebook provides clinical endocrinologists with the best real-world strategies to properly diagnose and treat the various presentations and symptoms they may encounter in daily practice. Discussing macroprolactinoma, non-functioning adenoma, TSH-secreting adenoma, Cushing's disease and acromegaly, each chapter is a case that provides a unique clinical presentation…
Available Online
View e-Book
Other Authors
Nachtigall, Lisa B.
Responsibility
Lisa B. Nachtigall, editor
Place of Publication
Cham
Publisher
Springer
Date of Publication
c2018
Physical Description
1 online resource (xii, 94 p.) : 1 illus.
ISBN
9783319909097
9783319909073 (print ed.)
9783319909080 (print ed.)
Subjects (MeSH)
Pituitary Neoplasms - therapy
Specialty
Endocrinology
Medical Oncology
Abstract
Comprised of cases presenting diverse clinical scenarios involving pituitary tumors and related conditions, this concise, practical casebook provides clinical endocrinologists with the best real-world strategies to properly diagnose and treat the various presentations and symptoms they may encounter in daily practice. Discussing macroprolactinoma, non-functioning adenoma, TSH-secreting adenoma, Cushing's disease and acromegaly, each chapter is a case that provides a unique clinical presentation of a patient's symptoms and clinical findings, diagnostic work-up and the thought process involved in navigating the treatment options, as well as the supporting evidence. Cases included illustrate different types of tumors, related disorders and special situations and considerations, in addition to various management strategies, complications and outcomes, with helpful clinical pearls and pitfalls. Pragmatic and reader-friendly, Pituitary Tumors: A Clinical Casebook is written by experts in the field and is designed to facilitate and guide endocrinologists in the sometimes challenging decision-making process by presenting real case scenarios that span the spectrum of pituitary tumor presentations and treatment options.
Contents
1. Macroprolactinoma: Diagnosis and Management in a Patient with Infertility -- 2. Macroprolactinoma: Alternatives to Dopamine Agonist Therapy for Treatment of Macroprolactinomas in Patients Who Present with Psychotic Symptoms -- 3. Nonfunctioning Pituitary Adenoma: Management -- 4. Cushing’s Disease: Common Pitfalls in Diagnosis -- 5. Management of Cushing’s Disease -- 6. Acromegaly: Diagnosis and Management in Patients Who Present with Discrepancy Between IGF-1 and GH -- 7. Acromegaly and Diabetes Mellitus: Special Considerations -- 8. Gigantism: Management of Fatigue and Daytime Sleepiness After Surgery and Radiation in Adolescents with GH Secreting Adenoma -- 9. A Rare Entity: TSH-Secreting Adenoma.
Format
e-Book
Publication Type
Case Reports
Location
Online
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Evidence-Based Endocrine Surgery

https://libcat.nshealth.ca/en/permalink/provcat42741
Rajeev Parameswaran, Amit Agarwal, editors. --Singapore: Springer , c2018.
Available Online
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Location
Online
In this textbook, leading experts from highly acclaimed institutions describe evidence-based best practice in the management of a wide range of benign and malignant thyroid, parathyroid, adrenal, and neuroendocrine conditions. Detailed attention is devoted to the current role of surgery, including minimally invasive surgery and robotic surgery, in different endocrine disorders. The reader will also learn how best to respond to the problems that may be encountered during endocrine surgical pract…
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Other Authors
Parameswaran, Rajeev
Agarwal, Amit
Responsibility
Rajeev Parameswaran, Amit Agarwal, editors
Place of Publication
Singapore
Publisher
Springer
Date of Publication
c2018
Physical Description
1 online resource (ix, 484 p.) : 94 illus., 65 illus. in color
ISBN
9789811011245
9789811011238 (print ed.)
9789811011252 (print ed.)
Subjects (MeSH)
Endocrine System Diseases - surgery
Endocrine Glands - surgery
Endocrine Surgical Procedures
Specialty
Endocrinology
Surgical Procedures, Operative
Abstract
In this textbook, leading experts from highly acclaimed institutions describe evidence-based best practice in the management of a wide range of benign and malignant thyroid, parathyroid, adrenal, and neuroendocrine conditions. Detailed attention is devoted to the current role of surgery, including minimally invasive surgery and robotic surgery, in different endocrine disorders. The reader will also learn how best to respond to the problems that may be encountered during endocrine surgical practice. While much of the focus is on surgical aspects, the approach is multidisciplinary, with inclusion of information on recent advances in epidemiology, genetics, cytology, pathology, imaging modalities, and other treatment options. The clear text is complemented by instructive clinical cases as well as numerous high-quality illustrations and tables summarizing key points. This book will be of value for specialists in endocrine medicine and surgery as well as general surgeons with an interest in endocrine surgery.
Contents
Part I. Thyroid -- 1. Evidence-Based Surgery -- 2. Graves’ Disease -- 3. Nodular Goitre -- 4. Epidemiology of Thyroid Cancer -- 5. Genetic Landscape of Thyroid Cancer -- 6. Updates in Thyroid Cytology -- 7. Imaging in Differentiated Thyroid Cancer -- 8. Management of Locally Advanced Thyroid Cancer -- 9. Neck Dissection in Well-Differentiated Thyroid Cancer -- 10. Radioiodine Therapy for Well-Differentiated Thyroid Cancer -- 11. Management of Distant Metastasis in Differentiated Thyroid Cancer -- 12. Medullary Thyroid Carcinoma -- 13. Anaplastic Thyroid Carcinoma -- 14. Inherited Thyroid Cancer -- 15. Neuromonitoring in Thyroid Surgery -- 16. Complications in Thyroid Surgery -- 17. Endoscopic and Robotic Thyroidectomy: An Evidence Approach -- Part II. Parathyroid -- 18. Primary Hyperparathyroidism -- 19. Parathyroid Imaging -- 20. Surgical Techniques and Adjuncts in Hyperparathyroidism -- 21. Hereditary Hyperparathyroidism -- 22. Renal Hyperparathyroidism -- 23. Revision Parathyroidectomy -- 24. Parathyroid Carcinoma: Current Concepts -- Part III. Adrenal -- 25. The Adrenal Incidentaloma -- 26. Cushing’s Syndrome -- 27. Conn’s Syndrome -- 28. Phaeochromocytoma -- 29. Surgery for Adrenocortical Cancer: Evidence-Based Recommendations -- 30. Paraganglioma -- 31. Perioperative Management of Endocrine Hypertension -- 32. Laparoscopic Adrenalectomy -- 33. Complications of Adrenal Surgery -- 34. Managing Adrenal Insufficiency and Crisis -- 35. Gastric and Duodenal Neuroendocrine Tumours -- 36. Pancreatic Neuroendocrine Tumours -- 37. Carcinoid Tumours of the Gastrointestinal System: Neuroendocrine Tumours of the Hindgut.
Format
e-Book
Location
Online
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Hypothalamic-Pituitary Diseases

https://libcat.nshealth.ca/en/permalink/provcat42803
Felipe F. Casanueva, Ezio Ghigo, editors. --Cham: Springer , c2018.
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Online
This book presents the state of the art in the pathophysiology, diagnosis, and therapy of hypothalamic and pituitary disorders. After an introduction devoted to the physiology of the neuroendocrine control of the hypothalamic-pituitary unit, the diverse disorders involving hormonal excess or deficiency are systematically addressed axis by axis. For each disorder, pathophysiology, clinical presentation, and management are discussed in detail. In addition, individual chapters focus on the neuroen…
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Other Authors
Casanueva, Felipe F.
Ghigo, Ezio
Responsibility
Felipe F. Casanueva, Ezio Ghigo, editors
Place of Publication
Cham
Publisher
Springer
Date of Publication
c2018
Physical Description
1 online resource (xix, 535 p.) : 54 illus., 31 illus. in color
Series Title
Springer reference
Endocrinology
ISBN
9783319444444
9783319444437 (print ed.)
ISSN
2510-1927
Subjects (MeSH)
Hypothalamic Diseases
Pituitary Diseases
Specialty
Endocrinology
Notes
"eReference"--Publisher.
Abstract
This book presents the state of the art in the pathophysiology, diagnosis, and therapy of hypothalamic and pituitary disorders. After an introduction devoted to the physiology of the neuroendocrine control of the hypothalamic-pituitary unit, the diverse disorders involving hormonal excess or deficiency are systematically addressed axis by axis. For each disorder, pathophysiology, clinical presentation, and management are discussed in detail. In addition, individual chapters focus on the neuroendocrinology of energy homeostasis and of bone metabolism, metabolic derangement secondary to pituitary dysfunction, and pituitary control of the endocrine pancreas. While the focus of the book is predominantly on pathophysiological and clinical aspects, due attention is also devoted to potential diagnostic and therapeutic innovations. The book is intended as a major reference for endocrinologists and basic and clinical scientists.
Contents
Chapter 1 Physiology of the hypothalamus pituitary unit -- Chapter 2 Physiopathology, diagnosis and treatment of GH Deficiency -- Chapter 3 Physiopathology, diagnosis and treatment of GH hypersecretion -- Chapter 4 Physiopathology, diagnosis and treatment of Non-functioning pituitary adenomas -- Chapter 5 Craniopharyngioma and Posttreatment Pituitary Dysfunction in Brain Tumors -- Chapter 6 Physiopathology, diagnosis and treatment of Functional pituitary dysfunction -- Chapter 7 Physiopathology, diagnosis and treatment of Secondary hypothyroidism -- Chapter 8 Physiopathology, diagnosis and treatment of Secondary hyperthyroidism -- Chapter 9 Physiopathology, Diagnosis, and Treatment of Secondary Female Hypogonadism -- Chapter 10 Central hypogonadism in the male: Physiopathology, diagnosis and treatment -- Chapter 11 Physiopathology, diagnosis and treatment of Hypercortisolism -- Chapter 12 Physiopathology, diagnosis and treatment of Diabetes insipidus -- Chapter 13 Physiopathology, Diagnosis and Treatment of Inappropriate ADH Secretion and Cerebral Salt Wasting Syndrome -- Chapter 14 Physiopathology, Diagnosis, and Treatment of Hyperprolactinemia -- Chapter 15 Neuroendocrinology of Energy Homeostasis -- Chapter 16 Neuroendocrine Control of Carbohydrate Metabolism -- Chapter 17 Neuroendocrinology of Bone Metabolism.
Format
e-Book
Location
Online
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Hormone Therapy and Castration Resistance of Prostate Cancer

https://libcat.nshealth.ca/en/permalink/provcat42814
Yoichi Arai, Osamu Ogawa, editors. --Singapore: Springer , c2018.
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Online
This comprehensive reference expounds the current state of hormone therapy and castration resistance of prostate cancer (PCa). Previously, the incidence of PCa in Asian countries was relatively low, but it has been increasing dramatically in recent years. Although most of the new cases are diagnosed in early stages, a significant proportion of patients receive hormone therapy for metastatic disease or for relapse after local treatment. Thus the situation has gradually changed toward earlier and…
Available Online
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Other Authors
Arai, Yoichi
Ogawa, Osamu
Responsibility
Yoichi Arai, Osamu Ogawa, editors
Place of Publication
Singapore
Publisher
Springer
Date of Publication
c2018
Physical Description
1 online resource (viii, 433 p.) : 65 illus., 34 illus. in color
ISBN
9789811070136
9789811070129 (print ed.)
9789811070143 (print ed.)
Subjects (MeSH)
Antineoplastic Agents, Hormonal - therapeutic use
Prostatic Neoplasms, Castration-Resistant - drug therapy
Specialty
Endocrinology
Medical Oncology
Urology
Abstract
This comprehensive reference expounds the current state of hormone therapy and castration resistance of prostate cancer (PCa). Previously, the incidence of PCa in Asian countries was relatively low, but it has been increasing dramatically in recent years. Although most of the new cases are diagnosed in early stages, a significant proportion of patients receive hormone therapy for metastatic disease or for relapse after local treatment. Thus the situation has gradually changed toward earlier and longer use of hormone therapy. The malignancy finally forms castration-resistant prostate cancer (CRPC) despite the lack of testicular androgen. With advances in understanding of the molecular basis of hormone dependence and CRPC, many new androgen receptor-targeted agents have emerged. During the last decade, much evidence on hormone therapy has been accumulated in Japan. Interestingly, some of these findings are different from those reported from Western countries, suggesting ethnic variation in the outcome of hormone therapy. In the chapters of this book, expert authors provide exhaustive interpretations of the evidence recently reported from Japan and provide important Asian perspectives on hormone therapy for PCa. This work benefits not only Asian urologists but also their Western counterparts and all physicians and medical personnel who are involved in the treatment of PCa.
Contents
1. Introduction -- 2. Recent trends in hormone therapy for prostate cancer in Japan -- 3. Risk assessment among patients receiving primary ADT -- 4. Patient-derived xenografts for research on hormonal therapy of prostate cancer -- 5. Impact of GnRH antagonist and LHRH agonist on the gonadal axis -- 6. Controversies on complete androgen blockade -- 7. Adrenal androgen in prostate cancer -- 8. Intermittent ADT for prostate cancer -- 9. Pognostic significance of monitoring serum testosterone in primary ADT -- 10. Ethnic variation in clinical outcomes of primary ADT for prostate cancer -- 11. ADT in combination with radical prostatectomy -- 12. ADT in combination with radiation therapy -- 13. ADT as salvage therapy after definitive treatment -- 14. ADT for clinically localised prostate cancer -- 15. Complications of ADT -- 16. Hot flash -- 17. Oseteoporosis and fracture risk -- 18. Metaboplic change -- 19. Bone scan index as a biomarker of bone metastasis -- 20. Genetic polymorphism analysis in predicting prognosis of metastatic prostate cancer -- 21. Local therapy in combination with ADT for metastatic prostate cancer -- 22. Oxidative stress and CRPC -- 23. Alternative antiandrogen therapy for CRPC -- 24. Optimization of sequential AR targeted therapy for CRPC -- 25. Enzalutamide therapy for mCRPC in Japanese men -- 26. Abiraterone acetate therapy for mCRPC in Japanese men -- 27. Role of estramustine phosphate for CRPC -- 28. Steroid therapy for CRPC -- 29. MicroRNA analysis in prostate cancer -- 30. AR splicing variant in prostate cancer -- 31. Detection of CTC in CRPC -- 32. New biomarker for CRPC: Glycobiologic perspective -- 33. Bone-tageted treatment in CRPC management -- 34. Skeletal complications in CRPC patients -- 35. Urological complications in men dying from prostate cancer -- 36. Prediction of optimal docetaxel regimen for patients with mCRPC -- 37. Intermittent chemotherapy with decetaxel for mCRPC -- 38. Chemotherapy with cabazitaxel for ìCRPC in Japanese men -- 39. New tageted approach to CRPC -- 40. Molecular basis of neuroendocrine prostate cancer -- 41. Gene therapy for prostate cancer -- 42. Immune therapy for CRPC -- 43. New approach to CRPC using inactivated virus -- 44. Patient-reported outcome in the management of CRPC.
Format
e-Book
Location
Online
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