Search Results - Provincial Hospitals Library Catalogue

The Ethics of Research Biobanking

https://libcat.nshealth.ca/en/permalink/provcat40939

Jan Helge Solbakk, Søren Holm, Bjørn Hofmann, editors. --New York, NY: Springer , c2009.

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The Ethics of Research Biobanking investigates some of the ethical, legal and social challenges raised by research biobanking. In the first part of the book, the authors pursue the different regulatory options envisaged within a normative terrain dictated by different conceptions and interpretations of the informed consent doctrine. In the second part, a completely new approach is explored. The authors investigate the conceptual potential of different analogies outside medical research used to …

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Other Authors: Solbakk, Jan Helge; Holm, Søren; Hofmann, Bjørn

Responsibility: Jan Helge Solbakk, Søren Holm, Bjørn Hofmann, editors

Place of Publication: New York, NY

Publisher: Springer

Date of Publication: c2009

Physical Description: 1 online resource (xviii, 357 p.)

ISBN: 9780387938721; 9780387938714 (print ed.)

Subjects (MeSH): Bioethical Issues; Biological Specimen Banks - ethics; Biomedical Research - ethics

Abstract: The Ethics of Research Biobanking investigates some of the ethical, legal and social challenges raised by research biobanking. In the first part of the book, the authors pursue the different regulatory options envisaged within a normative terrain dictated by different conceptions and interpretations of the informed consent doctrine. In the second part, a completely new approach is explored. The authors investigate the conceptual potential of different analogies outside medical research used to depict people's change and exchange of valuables between themselves and a common institution. The book is aimed at both academic and professional audiences (biobank curators, biobank researchers, ethicists, gene-epidemiologists, health law experts, philosophers, social scientists and advanced and graduate students in the relevant disciplines) as well as health and research regulators, ministries, politicians and the general public.

Contents: Research Biobanking: The Traditional Approach -- Consent to Biobank Research: One Size Fits All? -- What No One Knows Cannot Hurt You: The Limits of Informed Consent in the Emerging World of Biobanking -- Users and Uses of the Biopolitics of Consent: A Study of DNA Banks -- Information Rights on the Edge of Ignorance -- The Dubious Uniqueness of Genetic Information -- Duties and Rights of Biobank Participants: Principled Autonomy, Consent, Voluntariness and Privacy -- Biobanking and Disclosure of Research Results: Addressing the Tension Between Professional Boundaries and Moral Intuition -- Biobanks and Our Common Good -- Trust, Distrust and Co-production: The Relationship Between Research Biobanks and Donors -- Scientific Citizenship, Benefit, and Protection in Population-Based Research -- Research Biobanking: Towards a New Conceptual Approach -- Mapping the Language of Research Biobanking: An Analogical Approach -- The Use of Analogical Reasoning in Umbilical Cord Blood Biobanking -- The Alexandria Plan: Creating Libraries for Human Tissue Research and Therapeutic Use -- The Art of Biocollections -- The Health Dugnad: Biobank Participation as the Solidary Pursuit of the Common Good -- Embodied Gifting: Reflections on the Role of Information in Biobank Recruitment -- Conscription to Biobank Research? -- Ownership Rights in Research Biobanks: Do We Need a New Kind of 'Biological Property'? -- Legal Challenges and Strategies in the Regulation of Research Biobanking -- Annexation of Life: The Biopolitics of Industrial Biology -- In the Ruins of Babel: Should Biobank Regulations be Harmonized?.

Format: e-Book

Location: Online

HIV/AIDS in U.S. Communities of Color

https://libcat.nshealth.ca/en/permalink/provcat40940

Valerie Stone, Bisola Ojikutu, M. Keith Rawlings, Kimberly Y. Smith, editors. --New York, NY: Springer , c2009.

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Location: Online

More people in communities of color are contracting, living with, and being treated for HIV/AIDS than ever before. In 2005, 71% of new AIDS cases were diagnosed in people of color. Though the number of racial and ethnic minority HIV/AIDS cases continues to grow, the health care community has been unable to adequately meet the unique medical needs of these populations. African-American, Latino/Latina, and other patients of color are less likely to seek medical care, have sufficient access to the…

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Other Authors: Stone, Valerie; Ojikutu, Bisola; Rawlings, M. Keith; Smith, Kimberly Y.

Responsibility: Valerie Stone, Bisola Ojikutu, M. Keith Rawlings, Kimberly Y. Smith, editors

Place of Publication: New York, NY

Publisher: Springer

Date of Publication: c2009

Physical Description: 1 online resource (x, 309 p. : 4 illus.)

ISBN: 9780387981529; 9780387981512 (print ed.)

Subjects (MeSH): Acquired immunodeficiency syndrome - ethnology; HIV Infections - ethnology; Minority Groups; Minority Health; Social Conditions

Other Subjects: United States - epidemiology

Abstract: More people in communities of color are contracting, living with, and being treated for HIV/AIDS than ever before. In 2005, 71% of new AIDS cases were diagnosed in people of color. Though the number of racial and ethnic minority HIV/AIDS cases continues to grow, the health care community has been unable to adequately meet the unique medical needs of these populations. African-American, Latino/Latina, and other patients of color are less likely to seek medical care, have sufficient access to the health care system, or receive the drugs they need for as long as they need them. HIV/AIDS in U.S. Communities of Color is an outstanding resource for any professional working with these underserved populations. Comprehensive chapters cover issues as far-reaching as: anti-retroviral therapy; dermatologic manifestations and co-morbidities of the disease in patients of color; unique risks to women and MSMs of color; participation of minority cases in HIV research; and substance abuse and mental health issues. Complied by world experts in HIV/AIDS, this book analyzes the main causes of treatment failure and promotes respect for individual and cultural values, teaching readers to provide responsive, patient-centered care and devise preventive strategies for communities of color.

Contents: The Epidemiology, Prevention and Control of HIV/AIDS among African Americans -- HIV/AIDS and Latino Populations in the US: Epidemiology, Prevention and Barriers to Care and Treatment -- Antiretroviral Therapy and Communities of Color -- Overcoming Challenges to Successful Treatment Outcomes in Minority Patients with HIV/AIDS -- Access to Culturally Competent Care for Patients Living with HIV/AIDS -- Women of Color and HIV/AIDS: Epidemiology, Clinical Aspects, and Management -- Management of Pregnancy in HIV-Infected Women and Prevention of Mother-to-Child Transmission -- The Dermatological Manifestations of HIV Infection in Ethnic Skin -- Comorbidities in Black Patients with HIV/AIDS -- Men Who Have Sex With Men of Color in the Age of AIDS: The Sociocultural Contexts of Stigma, Marginalization, and Structural Inequalities -- HIV Prevention and Heterosexual African American Women -- Substance Abuse, HIV and Mental Health Issues: Prevention and Treatment Changes -- African Americans and HIV Research -- The Impact of HIV Policies and Politics on Communities of Color -- Moving Toward a Unified Global HIV/AIDS Agenda: Communities of Color in Crisis.

Format: e-Book

Location: Online

Liver Cancer

https://libcat.nshealth.ca/en/permalink/provcat40941

edited by M. A. Hayat. --Dordrecht: Springer , c2009.

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This fifth volume of the series, Methods of Cancer Diagnosis, Therapy, and Prognosis, discusses in detail the diagnosis, treatment, and prognosis of liver cancer. Both standard and emerging therapies for this cancer, written by expert oncologists/pathologists in this field, are included. This fully illustrated volume is divided into 7 sections: Applications of Imaging, Resectable Liver Cancer, Unresectable Liver Cancer, Hepatocellular Cancer, Liver Colorectal Metastasis, Biliary Cancer, and Spl…

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Other Authors: Hayat, M. A

Responsibility: edited by M. A. Hayat

Alternate Title: Methods of cancer diagnosis, therapy, and prognosis

Place of Publication: Dordrecht

Publisher: Springer

Date of Publication: c2009

Physical Description: 1 online resource (xliv, 514 p. : illus.)

Series Vol.: v. 5

Series Title: Methods of cancer diagnosis, therapy, and prognosis

ISBN: 9781402098048; 9781402098031 (print ed.)

Subjects (MeSH): Liver Neoplasms - diagnosis; Liver Neoplasms - therapy; Neoplasm Metastasis

Abstract: This fifth volume of the series, Methods of Cancer Diagnosis, Therapy, and Prognosis, discusses in detail the diagnosis, treatment, and prognosis of liver cancer. Both standard and emerging therapies for this cancer, written by expert oncologists/pathologists in this field, are included. This fully illustrated volume is divided into 7 sections: Applications of Imaging, Resectable Liver Cancer, Unresectable Liver Cancer, Hepatocellular Cancer, Liver Colorectal Metastasis, Biliary Cancer, and Splenic Cancer. The book discusses imaging modalities for diagnosis, treatment assessment, and prognosis. Includes descriptions of radial magnetic resonance imaging, helical computed tomography, magnetic resonance imaging, FDG-PET, contrast-enhanced sonography, multidetector-row computed tomography, and single photon emission computed tomography. Presents imaging methods for localized fibrous tumors of the liver, abdominal neoplasms, cholangiocarcinoma, gall bladder carcinoma, hepatic cellular carcinoma, extrahepatic disease, intrahepatic disease, focal liver lesions, biliary cystic tumors, extra hepatic bile duct carcinoma, and splenic metastases. Highlights methods for treatment of hepatocellular carcinoma (HCC) with thalidomide and transarterial treatment of hepatic malignancies. Discusses postoperative interferon alpha treatment of patients with HCC. Details the methods of immunohistochemistry, tissue microarray, and proteomic analysis for diagnosis and prognosis. The technological advances presented in this volume are expected to expedite new discoveries and their translation to clinical practice. The field of oncology will benefit the most from these advanced methods, as a combination of therapies and personalized medicine will improve early detection of liver cancer and other cancer types. Professor Hayat has summarized the problems associated with the complexities of research publications and has been successful in editing a must-read volume for oncologists, cancer researchers, medical teachers and students of cancer biology.

Contents: Liver Cancer -- Applications of Positron Emission Tomography in Liver Imaging: An Overview -- Localized Fibrous Tumor of the Liver: Imaging Features -- A Radial Magnetic Resonance Imaging Method for Imaging Abdominal Neoplasms -- Liver: Helical Computed Tomography and Magnetic Resonance Imaging -- Resectable Liver Cancer -- Selection of Patients for Resection of Hepatic Colorectal Metastases: 18F-Fluorodeoxyglucose/Positron Emission Tomography -- Ultrasonography During Liver Surgery -- Unresectable Liver Cancer -- Intraoperative Magnetic Resonance Imaging for Radiofrequency Ablation of Hepatic Tumors -- Surgically Unresectable and Chemotherapy-Refractory Metastatic Liver Carcinoma: Treatment with Yttrium-90 Microsphere Followed by Assessment with Positron Emission Tomography -- Unresectable Liver Metastases from Colorectal Cancer: Methodology and Prognosis with Radiofrequency Ablation -- Hepatocellular Carcinoma -- Screening with Ultrasonography of Patients at High-Risk for Hepatocellular Carcinoma: Thrombocytopenia as a Valid Surrogate of Cirrhosis -- Hepatocellular Carcinoma: Contrast-Enhanced Sonography -- Focal Liver Lesion: Nonlinear Contrast-Enhanced Ultrasound Imaging -- Hepatocellular Carcinoma: Magnetic Resonance Imaging -- Expression of Vascular Endothelial Growth Factor in Hepatocellular Carcinoma: Correlation with Radiologic Findings -- Detection of Small Hepatic Lesions: Superparamagnetic Oxide-Enhanced Diffusion-Weighted T2 FSE Imaging -- Diagnosis of Hepatocellular Carcinoma: Multidetector-Row Computed Tomography and Magnetic Resonance Imaging -- Hepatocellular Carcinoma: Effect of Injection Rate/Injection Duration of Contrast Material on Computed Tomography -- Detection of Combined Hepatocellular and Cholangiocarcinomas: Enhanced Computed Tomography -- Hepatocellular Carcinoma and Adenomatous Hyperplasia (Dysplastic Nodules): Dynamic Computed Tomography and a Combination of Computed Tomography and Angiography -- Hepatocellular Cancer in Cirrhotic Patients: Radiological Imaging -- Treatment of Hepatocellular Carcinoma with Thalidomide: Assessment with Power Doppler Ultrasound -- Perfusion Scintigraphy with Integrated Single Photon Emission Computed Tomography/Computed Tomography in the Management of Transarterial Treatment of Hepatic Malignancies -- Postoperative Interferon Alpha Treatment of Patients with Hepatocellular Carcinoma: Expression of p48 Using Tissue Microarray -- Hepatocellular Carcinoma: Overexpression of Homeoprotein Six 1 as a Marker for Predicting Survival -- Hepatocellular Carcinoma: KiSS-1 Overexpression as a Prognostic Factor -- Hepatocellular Carcinoma: Prognosis Using Hepatoma-Derived Growth Factor Immunohistochemistry -- Hepatitis C Virus-Related Human Hepatocellular Carcinoma: Predictive Markers Using Proteomic Analysis (Methodology) -- Metastases -- Liver Metastases from Colorectal Cancer: Ultrasound Imaging -- Preclinical Liver Metastases: Three-Dimensional High-Frequency Ultrasound Imaging -- Colorectal Liver Metastases: 18F-Fluorodeoxyglucose-Positron Emission Tomography -- Biliary Cancer -- Biliary Cystic Tumors: Clinicopathological Features -- Cholangiocarcinoma: Intraductal Sonography -- Extrahepatic Bile Duct Carcinoma: Role of the p53 Protein Family -- Extrahepatic Bile Duct Carcinoma: Mucin 4, a Poor Prognostic Factor -- Hilar Cholangiocarcinoma: Photodynamic Therapy and Stenting -- Splenic Cancer -- Splenic Metastases: Diagnostic Methods.

Format: e-Book

Location: Online

Chemokine Receptors in Cancer

https://libcat.nshealth.ca/en/permalink/provcat40943

Amy M. Fulton, editor. --New York, NY: Humana Press , c2009.

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Chemokine Receptors in Cancer summarizes the growing body of evidence that several chemokine receptors contribute to tumor behavior. Chemokine receptors were first identified on leukocytes and mediate directed migration of many host cells to sites of ligand expression. It is now well established that most malignant cells also express one or more chemokine receptor. This book describes our current understanding regarding how chemokine receptors contribute to tumor cell migration as well as cell …

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Other Authors: Fulton, Amy M

Responsibility: Amy M. Fulton, editor

Place of Publication: New York, NY

Publisher: Humana Press

Date of Publication: c2009

Physical Description: 1 online resource (x, 176 p. : 13 illus.)

Series Title: Cancer drug discovery and development

ISBN: 9781603272674; 9781603272667 (print ed.)

Subjects (MeSH): Angiogenesis Inducing Agents; Neoplasms; Receptors, Chemokine - drug effects

Abstract: Chemokine Receptors in Cancer summarizes the growing body of evidence that several chemokine receptors contribute to tumor behavior. Chemokine receptors were first identified on leukocytes and mediate directed migration of many host cells to sites of ligand expression. It is now well established that most malignant cells also express one or more chemokine receptor. This book describes our current understanding regarding how chemokine receptors contribute to tumor cell migration as well as cell survival and proliferation. The function of chemokine receptors expressed on host cells including antitumor immune effector cells as well as angiostatic and angiogeneic functions of chemokines acting on endothelial cells are described. The role of chemokine receptors that act as decoy receptors is also summarized. The therapeutic potential and challenges of targeting chemokine receptors or cognate ligands is also addressed.

Contents: Chemokines and Chemokine Receptors in Cancer Progression -- CXCR4 and Cancer -- HIF-1 Regulation of Chemokine Receptor Expression -- Chemokine Receptors Involved in Colon Cancer Progression, and Lymph Node Metastasis -- The CXCR3/CXCL3 Axis in Cancer -- Roles for CCR7 in Cancer Biology -- The CCL5/CCR5 Axis in Cancer -- CXC Chemokines in Cancer Angiogenesis -- The Roles of Chemokines and Chemokine Receptors in Prostate Cancer.

Format: e-Book

Location: Online

Telomeres and Telomerase in Cancer

https://libcat.nshealth.ca/en/permalink/provcat40944

Keiko Hiyama, editor. --New York, NY: Springer , c2009.

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Telomeres and telomerase are the pivotal players that destine cellular senescence and immortalization. Telomere shortening due to "End-replication problem" in each cell cycle is a universal phenomenon for all eukaryotic cells with linear chromosomes. Its compensation by telomerase is also common from yeast to human. However, the length of telomeres, distribution of telomerase positive cells, and consequence of telomerase inhibition are different among species. "Telomeres and Telomerase in Cance…

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Other Authors: Hiyama, Keiko

Responsibility: Keiko Hiyama, editor

Place of Publication: New York, NY

Publisher: Springer

Date of Publication: c2009

Physical Description: 1 online resource (xii, 373 p. : 60 illus., 19 illus. in color)

Series Title: Cancer drug discovery and development

ISBN: 9781603278799; 9781603273060 (print ed.)

Subjects (MeSH): Antineoplastic Agents - therapeutic use; Cell Transformation, Neoplastic; Neoplasms - drug therapy; Telomerase - antagonists & inhibitors; Telomere - genetics; Telomere-Binding Proteins

Abstract: Telomeres and telomerase are the pivotal players that destine cellular senescence and immortalization. Telomere shortening due to "End-replication problem" in each cell cycle is a universal phenomenon for all eukaryotic cells with linear chromosomes. Its compensation by telomerase is also common from yeast to human. However, the length of telomeres, distribution of telomerase positive cells, and consequence of telomerase inhibition are different among species. "Telomeres and Telomerase in Cancers", edited by Keiko Hiyama, focuses on "Human" telomeres and telomerase, from basic biology and hypothesis in human normal cells and cancer cells to clinical application as diagnostic tools and therapeutic targets in anti-cancer strategy. Cutting-edge experimental protocols for their evaluation are also included. This coverage will enable medical oncologists and students as well as basic researchers to capture the up-to-date entire picture of human telomeres and telomerase in cancer.

Contents: Part I. Basic Background -- Telomeres and Telomerase in Humans -- Telomere-Binding Proteins in Humans -- Regulation of Telomerase Through Transcriptional and Posttranslational Mechanisms -- Telomere Dysfunction and the DNA Damage Response -- Alternative Lengthening of Telomeres in Human Cells -- Mouse Model: Telomeres and Telomerase in Stem Cell and Cancer -- Part II. Telomeres and Telomerase in Human Cancers -- Role of Telomeres and Telomerase in Cancer -- Diagnostic Value I: Solid Tumors -- Diagnostic Value II: Hematopoietic Malignancies -- Therapeutic Targets and Drugs I: Telomerase and Telomerase Inhibitors -- Therapeutic Targets and Drugs II: G-Quadruplex and G-Quadruplex Inhibitors -- Therapeutic Targets and Drugs III: Tankyrase 1, Telomere-Binding Proteins, and Inhibitors -- Therapeutic Targets and Drugs IV: Telomerase-Specific Gene and Vector-Based Therapies for Human Cancer -- Part III. Experimental Protocols -- Protocol I: Telomerase Activity and Telomerase Expression -- Protocol II: Importance and Methods of Telomere G-Tail Length Quantification -- Protocol III: Detection of Alternative Lengthening of Telomeres.

Format: e-Book

Location: Online

Women's Cancers : Pathways to Healing : A Patient's Guide to Dealing with Cancer and Abnormal Smears

https://libcat.nshealth.ca/en/permalink/provcat40945

J. Richard Smith ; co-author, Giuseppe Del Priore. --London: Springer , c2009.

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Women's Cancers: Pathway to Healing - A Patient's Guide to Dealing Ovarian and Breast Cancer provides accurate information that combines both orthodox medical treatments, along with more complementary and esoteric therapies. Giving not only a valuable source of information and support to women with cancer, it also proves a useful resource for families and friends; helping them to understand the process of management and treatment. The book incorporates a useful and novel "4-cusp approach," whic…

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Author: Smith, J. Richard

Other Authors: Priore, Giuseppe Del

Responsibility: J. Richard Smith ; co-author, Giuseppe Del Priore

Place of Publication: London

Publisher: Springer

Date of Publication: c2009

Physical Description: 1 online resource (xvi, 138 p. : 47 illus.)

ISBN: 9781846284380; 9781846284373 (print ed.)

Subjects (MeSH): Neoplasms - psychology; Neoplasms - therapy; Women's Health

Abstract: Women's Cancers: Pathway to Healing - A Patient's Guide to Dealing Ovarian and Breast Cancer provides accurate information that combines both orthodox medical treatments, along with more complementary and esoteric therapies. Giving not only a valuable source of information and support to women with cancer, it also proves a useful resource for families and friends; helping them to understand the process of management and treatment. The book incorporates a useful and novel "4-cusp approach," which has proved very helpful to many women, both to themselves and also in allowing them to explain to their families where they are in the process. The "4-cusp approach" is like a map for people with cancer. Covering not only the medical, but also the emotional and psychological aspects of dealing with cancer, Pathways to Healing: A Patient's Guide to Ovarian and Breast Cancer aims to help anyone struggling to come to terms with their own, or a loved one's grief. Richard Smith, MD, FRCOG, Consultant Gynecological Surgeon at Chelsea and Westminster Hospital and Honorary Gynecologist at Royal Brompton Hospital, UK amongst many others. Dr Giuseppe Del Priore, Gynecologist specialising in cancer treatment. He works at New York University School of Medicine in New York City, USA and has a long standing interest in doctor-patient communication. He has been a pioneer in the field of fertility sparing surgery.

Contents: General Information -- General Introduction -- Anatomy Overview -- The 4-cusp Approach to Cancer Care -- General Concepts of Surgical Management -- Sex, Cancer, and Surgery -- Specific Cancers -- Cervical Cancer and Precancer (Cervical Intraepithelial Neoplasia) -- Ovarian Cancer (Including Cancer of the Fallopian Tube) -- Endometrial Cancer -- Vulval Cancer -- Breast Cancer -- Choriocarcinoma: Gestational Trophoblastic Neoplasia -- General Treatments and Care -- General Concepts of Chemotherapy and Radiotherapy -- Pain Management -- Complementary Therapies -- Bereavement/Grief -- Spiritual Approaches to Living with Cancer -- Conclusion.

Format: e-Book

Publication Type: Popular Works

Location: Online

Understanding Hughes Syndrome : Case Studies for Patients

https://libcat.nshealth.ca/en/permalink/provcat40948

Graham R. V. Hughes. --London: Springer , c2009.

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Location: Online

Antiphospholipid Syndrome or Hughes Syndrome was the major medical discovery of the late 20th century; for many it is still deemed a new disease. As a result many people are now living with the disease with little knowledge of its causes, effects and available treatments. Many of these patients are also struggling to cope with the daily demands posed by living with such an illness. Understanding Hughes Syndrome: Case Studies for Patients, presents 50 case histories, each covered independently t…

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Author: Hughes, Graham R. V

Responsibility: Graham R. V. Hughes

Place of Publication: London

Publisher: Springer

Date of Publication: c2009

Physical Description: 1 online resource (xiv, 94 p.)

ISBN: 9781848003767; 9781848009325 (print ed.)

Subjects (MeSH): Antiphospholipid Syndrome

Abstract: Antiphospholipid Syndrome or Hughes Syndrome was the major medical discovery of the late 20th century; for many it is still deemed a new disease. As a result many people are now living with the disease with little knowledge of its causes, effects and available treatments. Many of these patients are also struggling to cope with the daily demands posed by living with such an illness. Understanding Hughes Syndrome: Case Studies for Patients, presents 50 case histories, each covered independently to give a comprehensive view of the vast spectrum that is Antiphospholipid Syndrome. Neurological aspects and effects are covered in approximately half the text, with the remainder covering everything from repeated miscarriages to easy bruising. The provision of personal accounts of Antiphospholipid Syndrome makes this book the ultimate companion to people living with the disease; giving not only the facts but also the personal touch that many people need when coming to terms, and dealing, with their condition. Understanding Hughes Syndrome: case studies for patients is written by Graham R.V. Hughes, MD, FRCP, a world-renowned expert in the field of rheumatology, and as the name suggests discoverer of Hughes or Antiphospholipid Syndrome. Hughes is also the Head of The London Lupus Centre, Founder and Editor of the international journal Lupus, and life president of the lupus patients charity Lupus UK.

Contents: The Brain -- Late for the Wedding -- Falling Over -- Diplomatic Epilepsy -- Weak Legs -- Multiple Sclerosis -- Teenage Migraine -- Getting Only Half the Picture -- Difficult Crossword Puzzles -- Playing the Wrong Notes -- Speaking Gibberish -- I Lost My Sense of Smell -- Movement, Jerks and Twitches -- Mad Cow Disease -- St. Vitus Dance -- Parkinson's Disease -- Missing the Target -- The Headmistress Who Forgot -- "Personality Disorder" in a 4-Year-Old -- To Sleep... Perchance to Dream -- ... and Other Organs -- Collapse at the Airport -- Ballerina's Leg Ulcers -- Twenty Years On -- "Heart Attack" -- Backpacking in Australia -- Short of Breath in Scandinavia -- Easy Bruising -- Addison's Disease: 200 Years On? -- Tummy Pain -- Impotence -- Severe Leg Pain -- Pain in the Foot (Toelitis) -- The Bells Are Ringing -- The Swollen Legs -- The Computer has Crashed (The Catastrophic APS) -- Pregnancy, Miscarriage, Infertility -- Eleven Miscarriages -- Late Pregnancy Tragedy -- The Infertility Clinic -- Causes and Effects -- The Pill and I -- A Bad Back -- A Miracle -- Climbing the Andes -- Fear of Flying -- The Lambeth Walk -- The Tests are Negative! -- Aspects of Treatment -- "My Sister has Hughes Syndrome" -- Trial and Error -- "I Saved the Country Ð73,000" -- What Happened Next? -- "Your Condition Doesn't Exist" -- "I've Got My Life Back!".

Format: e-Book

Publication Type: Case Reports; Popular Works

Location: Online

Th 17 Cells : Role in Inflammation and Autoimmune Disease

https://libcat.nshealth.ca/en/permalink/provcat40954

Valérie Quesniaux, Bernhard Ryffel, Franco Di Padova, editors. --Basel: Birkhäuser Verlag , c2009.

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Location: Online

With the recent definition of the Th17 cell subset, a new paradigm in innate and adaptive immunity has been established. This book describes the function of the Th17 cell subset and its prevalent role in many inflammatory and autoimmune diseases. The mechanism by which this T cell subset is generated and maintained shows specific differences between mice and man which are reviewed. One characteristic of Th17 cells is to secrete specific and unique cytokines such as IL-17A, IL-17F and IL-22; the…

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Other Authors: Quesniaux, Valérie; Ryffel, Bernhard; Padova, Franco Di

Responsibility: Valérie Quesniaux, Bernhard Ryffel, Franco Di Padova, editors

Place of Publication: Basel

Publisher: Birkhäuser Verlag

Date of Publication: c2009

Physical Description: 1 online resource (xii, 244 p. : 20 illus.)

Series Title: Progress in inflammation research

ISBN: 9783764386818; 9783764386801 (print ed.)

Subjects (MeSH): Antibodies, Neutralizing; Autoimmune Diseases - etiology; Inflammation - etiology; Th17 Cells - immunology

Abstract: With the recent definition of the Th17 cell subset, a new paradigm in innate and adaptive immunity has been established. This book describes the function of the Th17 cell subset and its prevalent role in many inflammatory and autoimmune diseases. The mechanism by which this T cell subset is generated and maintained shows specific differences between mice and man which are reviewed. One characteristic of Th17 cells is to secrete specific and unique cytokines such as IL-17A, IL-17F and IL-22; their functions are described in detail. These cytokines have acquired a prevalent role in many pathological conditions in animal models and in humans. Targeting these cytokines as well as the generation of Th17 cells may open new ways to treat many autoimmune diseases. The role of Th17 in infectious conditions is also addressed.

Contents: Discovery and IL-17 family -- IL-22 and IL-17: Common and different properties -- Other sources of IL-17: Invariant natural killer T cells -- Contributions of IL-22 to Th17 responses: Repairing and protecting peripheral tissues -- Retinoic acid in mucosal immune-regulation -- IL-25, another promoter of allergy -- Experimental models of disease -- Critical role of IL-17 in experimental arthritis -- Dual role of IL-17 in allergic asthma -- Contribution of IL-17 to the pulmonary inflammatory response -- The role of IL-17 in experimental autoimmune myocarditis -- Th17 cells in organ transplantation -- Role of IL-23/IL-17 in infection and tumor control -- Is IL-17 required to control tuberculosis? -- IL-17 and mucosal host defense -- IL-23 orchestrates the switch from tumor immune surveillance to tumor-promoting inflammation -- IL-17 in clinical autoimmune disease -- IL-17 and Th17 cells in rheumatoid arthritis -- Targeting Th17 cells in CNS immune pathology -- IL-17 cytokines in asthma -- IL-17/23, potential targets for Crohn's disease -- Novel tools and therapeutic avenues -- IL-17A and Th17 cells as therapeutic targets for autoimmune diseases.

Format: e-Book

Location: Online

Gender and Recovery from Coronary Artery Bypass Surgery : A Psychological Perspective

https://libcat.nshealth.ca/en/permalink/provcat40955

Friederike Kendel. --Darmstadt: Steinkopff , c2009.

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Location: Online

The number of coronary artery bypass graft (CABG) operations has increased continually over the past decade. To date, roughly one-third of these are performed on women. Despite the tremendous progress made in cardiovascular surgery, not all patients profit equally from it, and the mortality rate of women still exceeds that of men by a factor of two. Studies conducted to investigate this marked gender difference have yielded conflicting results. In particular, adjustment for clinical risk factor…

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Author: Kendel, Friederike

Responsibility: Friederike Kendel

Place of Publication: Darmstadt

Publisher: Steinkopff

Date of Publication: c2009

Physical Description: 1 online resource (viii, 98 p. : 11 illus., 8 illus. in color)

Series Vol.: 7

Series Title: Fortschritte der Herz-, Thorax- und Gefäßchirurgie

ISBN: 9783798518568; 9783798518551 (print ed.)

Subjects (MeSH): Coronary Artery Bypass - psychology; Coronary Artery Bypass - rehabilitation; Sex Factors

Abstract: The number of coronary artery bypass graft (CABG) operations has increased continually over the past decade. To date, roughly one-third of these are performed on women. Despite the tremendous progress made in cardiovascular surgery, not all patients profit equally from it, and the mortality rate of women still exceeds that of men by a factor of two. Studies conducted to investigate this marked gender difference have yielded conflicting results. In particular, adjustment for clinical risk factors seemed to diminish the difference, but could not fully explain it. Therefore psychosocial parameters, in particular depression and psychosocial stress, have gained increasing attention as predictors for both mortality and quality of life after CABG operation. Gender differences in these variables have long been observed in patients undergoing CABG: female patients are on average older, more often depressive and more often living alone than male patients. This book presents the very first German study to focus on these gender differences. By describing the gender-specific influence of psychological and clinical variables on the recovery process, this work fills an important gap in cardiovascular research. Its approach is interdisciplinary in the best sense. The study underlines the importance of psychosocial variables for both mortality and quality of life in the context of CABG. Thus, it may be seen as a basis for a better understanding and treatment of CABG patients.

Contents: 1. Introduction -- 1.1 Gender Differences in Mortality After CABG -- 1.2 Gender Aspects of Risk Factors -- 1.3 Outcome Measures -- 2. Hypotheses -- 2.1 Gender Differences in Risk Factors and Outcomes -- 2.2 Moderator Hypotheses -- 2.3 Mediator Hypotheses -- 3. Method -- 3.1 Participants -- 3.2 Measurements -- 3.3 General Statistical Procedures -- 3.4 Sample -- 4. Results -- 4.1 Predictors of Mortality and Physical Functioning Based on Preoperative Data -- 4.2 Predictors of Well-Being Based on Longitudinal Data -- 4.3 Predictive Relationship Between Physical Functioning and Depression -- 5. Discussion -- 5.1 Gender Differences in Outcome -- 5.2 Gender Aspects in Recovery -- 5.3 Is Depression Predictive for Physical Functioning? -- 5.4 Limitations -- 5.5 Clinical Implications -- 5.6 Conclusion -- 6. Summary -- 7. Zusammenfassung -- 8. References.

Format: e-Book

Location: Online

Reprogen-ethics and the future of gender

https://libcat.nshealth.ca/en/permalink/provcat40956

Frida Simonstein, editor. --Dordrecht: Springer , c2009.

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Location: Online

'Reprogen-Ethics and the Future of Gender' brings together three tightly related topics, which have so far been dealt separately in bioethics: assisted reproduction, enhancing and gender. Part one in this book targets present policies and legislature of assisted reproduction. Part two focuses on current views of the ethics of PGD and enhancing. Part three tackles the future of gender. Part four deals with artificial wombs and ectogenesis. The aim of this book is to provide a joint perspective i…

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Other Authors: Simonstein, Frida

Responsibility: Frida Simonstein, editor

Place of Publication: Dordrecht

Publisher: Springer

Date of Publication: c2009

Physical Description: 1 online resource (xiv, 224 p.)

Series Vol.: v. 43

Series Title: International library of ethics, law, and the new medicine

ISBN: 9789048124756; 9789048124749 (print ed.)

ISSN: 1567-8008

Subjects (MeSH): Bioethical Issues; Genetic Enhancement - ethics; Reproductive Techniques, Assisted - ethics; Sex Preselection - ethics; Socioeconomic Factors

Abstract: 'Reprogen-Ethics and the Future of Gender' brings together three tightly related topics, which have so far been dealt separately in bioethics: assisted reproduction, enhancing and gender. Part one in this book targets present policies and legislature of assisted reproduction. Part two focuses on current views of the ethics of PGD and enhancing. Part three tackles the future of gender. Part four deals with artificial wombs and ectogenesis. The aim of this book is to provide a joint perspective in order to get the big picture. Contributors include Matti Häyry, Tuija Takala, Søren Holm, David Heyd, Daniel Callahan, Harriet Bradley, Ekaterina Balabanova and others. Some chapters in this book will significantly contribute to the current discussion of the topics at stake; other chapters will start a discussion on issues that have not yet been discussed. "Reprogen-Ethics and the Future of Gender" will certainly appeal to readers who are interested in any of the intersecting topics of assisted reproduction, genetic enhancing and gender; bioethicists, sociologists, genetic counsellors, gynaecologists, legislators, and students of the relevant disciplines.

Contents: Introduction -- Part I. ART – A 30 Years Retrospective -- 1. Current Status of Assisted Reproductive Techniques (ART) -- 2. The Medicalization of Reproduction – A 30 Year Retrospective -- 3. Conceiving a New Right to Procreate -- Part II. ART – Mind the Gap -- 4. ‘Can’t Avoid It, Can’t Afford It’: Assisted Reproduction in Israel and Bulgaria -- 5. Assisted Reproduction in Developing Countries: The Debate at a Turning Point -- 6. Ethical and Socio-Cultural Aspects that Influence ART in Latin America -- Part III. Gendered Futures -- 7. Women, Work, and Children: Is There a Solution? -- 8. Between Fecklessness and Selfishness: Is There a Biologically Optimal Time for Motherhood? -- 9. Gendered Futures: Reproduction and Production inWomen’s Lives -- Part IV. Parenting -- 10. Is Transferred Parental Responsibility Legitimately Enforceable? -- 11. Reproduction, Responsibility and Rationality -- 12. Male or Female We Will Create Them: The Ethics of Sex Selection for Non-medical Reasons -- Part V. Non-gendered Futures 13. Artificial Reproductive Technologies and the Advent of the Artificial Womb -- 14. Human Before Sex? Ectogenesis as a Way to Equality -- 15. The GlassWomb -- 16. A Survey of People’s Attitude Towards the Artificial Womb and Ectogenesis in Israel.

Format: e-Book

Location: Online

Denying AIDS : conspiracy theories, pseudoscience, and human tragedy

https://libcat.nshealth.ca/en/permalink/provcat40970

Seth C. Kalichman ; foreward by Nicoli Nattarass. --New York, NY: Copernicus Books , c2009.

Available Online: View e-Book

Location: Online

Paralleling the discovery of HIV and the rise of the AIDS pandemic, a flock of naysayers has dedicated itself to replacing genuine knowledge with destructive misinformation and spreading from the fringe to the mainstream media and the think tank. Now from the editor of the journal AIDS and Behavior comes a bold exposé of the scientific and sociopolitical forces involved in this toxic evasion. Denying AIDS traces the origins of AIDS dissidents disclaimers during the earliest days of the epidemic…

Available Online: View e-Book

Author: Kalichman, Seth C.

Responsibility: Seth C. Kalichman ; foreward by Nicoli Nattarass

Place of Publication: New York, NY

Publisher: Copernicus Books

Date of Publication: c2009

Physical Description: 1 online resource (xviii, 205 p. : ill.)

ISBN: 9780387794761; 9780387794754 (print ed.)

Subjects (MeSH): Acquired Immunodeficiency Syndrome - psychology; Anti-HIV Agents; Denial (Psychology); Health Policy; Quackery

Abstract: Paralleling the discovery of HIV and the rise of the AIDS pandemic, a flock of naysayers has dedicated itself to replacing genuine knowledge with destructive misinformation and spreading from the fringe to the mainstream media and the think tank. Now from the editor of the journal AIDS and Behavior comes a bold exposé of the scientific and sociopolitical forces involved in this toxic evasion. Denying AIDS traces the origins of AIDS dissidents disclaimers during the earliest days of the epidemic and delves into the psychology and politics of the current denial movement in its various incarnations. Seth Kalichman focuses not on the “difficult” or doubting patient, but on organized, widespread forms of denial (including the idea that HIV itself is a myth and HIV treatments are poison) and the junk science, faulty logic, conspiracy theories, and larger forces of homophobia and racism that fuel them. The malignant results of AIDS denial can be seen in those individuals who refuse to be tested, ignore their diagnoses, or reject the treatments that could save their lives. Instead of ignoring these currents, asserts Kalichman, science has a duty to counter them. Among the topics covered include: why AIDS denialism endures, and why science must understand it, pioneer virus HIV researcher Peter Duesberg’s role in AIDS denialism, the social conservative agenda and the politics of AIDS denial, from the courts to the White House, yhe impact of HIV misinformation on public health in South Africa and fighting fiction with reality: anti-denialism and the scientific community. For anyone affected by, interested in, or working with researchers in HIV/AIDS, and public health professionals in general, the insight and vision of Denying AIDS will inspire outrage, discussion, and ultimately action.

Contents: HIV/AIDS Denialism Is Alive and Well -- Peter Duesberg and the Origins of HIV/AIDS Denialism -- AIDS Pseudoscience -- Denalist Journalism and Conspiracy Theories -- Politics of Denialsm -- Getting Out of Denial -- Epilogue: The Most Ironic Conspiracy.

Format: e-Book

Location: Online

Disease, diagnoses, and dollars : facing the ever-expanding market for medical care

https://libcat.nshealth.ca/en/permalink/provcat40971

Robert M. Kaplan. --New York: Copernicus Books , c2009.

Available Online: View e-Book

Location: Online

Available Online: View e-Book

Author: Kaplan, Robert M (Robert Malcolm) 1947-

Responsibility: Robert M. Kaplan

Place of Publication: New York

Publisher: Copernicus Books

Date of Publication: c2009

Physical Description: 1 online resource (xvii, 187 p. : ill.)

ISBN: 9780387740454; 9780387740447 (print ed.)

Subjects (MeSH): Diagnostic Techniques and Procedures - economics; Economics, Medical; Health Care Costs; Health Policy

Other Subjects: United States

Contents: 1. Disease, Outcomes, and Money -- 2. The Disease-Reservoir Hypothesis -- 3. Mental Models of Health and Healthcare -- 4. What Is Disease and When Does It Begin? -- 5. Screening for Cancer -- 6. Deciding When Blood Pressure Is Too High -- 7. The Cholesterol Cutoff -- 8. Diabetes, Obesity, and the Metabolic Syndrome -- 9. Cost-Effectiveness and Opportunity Costs -- 10. Shared Medical Decision-Making -- 11. Putting the Pieces Together.

Format: e-Book

Location: Online

Intraepithelial neoplasia

https://libcat.nshealth.ca/en/permalink/provcat40972

Maode Lai, editor. --Beijing, China: Higher Education Press , c2009.

Available Online: View e-Book

Location: Online

Intraepithelial neoplasia (IEN) are some kind of preinvasive lesions. The definition and identification of intraepithelial neoplasia is exceedingly important for early diagnosis and prevention of malignancy. This book introduces for the first time the concept of intraepithelial neoplasia for the entire body in detail and the diagnostic applications of intraepithelial neoplasia in many organs and systems – including the respiratory and digestive systems, pancreas, bile duct, breast, prostate, ur…

Available Online: View e-Book

Other Authors: Lai, Maode

Responsibility: Maode Lai, editor

Place of Publication: Beijing, China

Publisher: Higher Education Press

Date of Publication: c2009

Physical Description: 1 online resource (xiii, 364 p. : ill.)

ISBN: 9783540854531; 9783540854524 (print ed.)

Subjects (MeSH): Carcinoma in Situ - diagnosis; Carcinoma in Situ - therapy; Precancerous Conditions - diagnosis; Precancerous Conditions - therapy

Abstract: Intraepithelial neoplasia (IEN) are some kind of preinvasive lesions. The definition and identification of intraepithelial neoplasia is exceedingly important for early diagnosis and prevention of malignancy. This book introduces for the first time the concept of intraepithelial neoplasia for the entire body in detail and the diagnostic applications of intraepithelial neoplasia in many organs and systems – including the respiratory and digestive systems, pancreas, bile duct, breast, prostate, urinary system, female genital system and the skin. The book features a large number of original figures – 450 – from Chinese patients with detailed descriptions. The book can serve as a diagnostic reference and as a research guide to preinvasive lesions for pathologists, oncologists and scientists. In addition, it will be able to help medical and pathology students improve their understanding of early neoplasia. Prof. Dr. med. Maode Lai is one of the most widely respected pathologists in China. He is vice president of Zhejiang University and Chairman-elect of the Chinese Society of Pathology. His major work is focused on molecular pathology of tumors, especially colorectal cancer.

Contents: Intraepithelial Neoplasia of the Respiratory Tract -- Intraepithelial Neoplasia of the Digestive Tract -- Intraepithelial Neoplasia of Pancreas, Biliary Tract and Gallbladder -- Intraepithelial Neoplasia of the Breast -- Prostatic Intraepithelial Neoplasia -- Urinary Intraepithelial Neoplasia (Intra-urothelial Neoplasia) -- Intraepithelial Neoplasia of the Female Reproductive Tract -- Intraepidermal Neoplasia of Skin --

Format: e-Book

Location: Online

Study guide to psychopharmacology : a companion to the American Psychiatric Publishing textbook of psychopharmacology, fourth edition

https://libcat.nshealth.ca/en/permalink/provcat42242

Robert E. Hales, Narriman C. Shahrokh, Alan F. Schatzberg, Charles B. Nemeroff. (First edition) --Arlington, VA: American Psychiatric Publishing , c2009.

Available Online: View e-Book

Location: Online

Available Online: View e-Book

Other Authors: Hales, Robert E.

Responsibility: Robert E. Hales, Narriman C. Shahrokh, Alan F. Schatzberg, Charles B. Nemeroff

Edition: First edition

Place of Publication: Arlington, VA

Publisher: American Psychiatric Publishing

Date of Publication: c2009

Physical Description: 1 online resource ([491] p.)

ISBN: 9781585623280; 9781585623549

Subjects (MeSH): Mental Disorders - drug therapy; Psychopharmacology; Psychotropic Drugs - therapeutic use

Format: e-Book

Publication Type: Examination Questions

Location: Online

Trauma stewardship : an everyday guide to caring for self while caring for others

https://libcat.nshealth.ca/en/permalink/provcat43850

Laura van Dernoot Lipsky, with Connie Burke. --San Francisco, CA: Berrett-Koehler Publishers , c2009.

Available Online: View e-Book

Location: Online

A longtime trauma worker, Laura van Dernoot Lipsky offers a deep and empathetic survey of the often-unrecognized toll taken on those working to make the world a better place. We may feel tired, cynical, or numb or like we can never do enough. These, and other symptoms, affect us individually and collectively, sapping the energy and effectiveness we so desperately need if we are to benefit humankind, other living things, and the planet itself.

Available Online: View e-Book

Author: Lipsky, Laura van Dernoot

Other Authors: Burke, Connie

Responsibility: Laura van Dernoot Lipsky, with Connie Burke

Place of Publication: San Francisco, CA

Publisher: Berrett-Koehler Publishers

Date of Publication: c2009

Physical Description: 1 online resource (265 p.)

Series: A BK life book

ISBN: 9781605092638

Subjects (MeSH): Caregivers - psychology; Self Care

Subjects (LCSH): Caregivers

Abstract: A longtime trauma worker, Laura van Dernoot Lipsky offers a deep and empathetic survey of the often-unrecognized toll taken on those working to make the world a better place. We may feel tired, cynical, or numb or like we can never do enough. These, and other symptoms, affect us individually and collectively, sapping the energy and effectiveness we so desperately need if we are to benefit humankind, other living things, and the planet itself.

Contents: Introduction: On the Cliff of Awakening -- Part 1: Understanding Trauma Stewardship -- 1. A New Vision for Our Collective Work -- 2. The Three Levels of Trauma Stewardship -- Part 2: Mapping Your Response to Trauma Exposure -- 3. What Is Trauma Exposure Response? -- 4. The 16 Warning Signs of Trauma Exposure Response -- Part 3: Creating change from the inside out -- 5. New Ways to Navigate -- 6. Coming into the Present Moment -- Part 4: Finding your way to trauma steardship -- 7. Following the Five Directions -- 8. North: Creating Space for Inquiry -- 9. East: Choosing Our Focus -- 10. South: Building Compassion and Community -- 11. West: Finding Balance -- 12. The Fifth Direction: A Daily Practice of Centering Ourselves -- Conclusion: Closing Intention.

Format: e-Book

Location: Online

Copies: 1

Pulmonary Problems in Pregnancy : Clinical and Research Aspects

https://libcat.nshealth.ca/en/permalink/provcat29609

edited by Karen Rosene-Montella, Ghada Bourjeily. --Totowa, NJ: Humana Press , c2009.

Available Online: View e-Book

Location: Online

Available Online: View e-Book

Author: Rosene-Montella, Karen

Other Authors: Bourjeily, Ghada

Responsibility: edited by Karen Rosene-Montella, Ghada Bourjeily

Place of Publication: Totowa, NJ

Publisher: Humana Press

Date of Publication: c2009

Series Title: Respiratory medicine (New York, N.Y.)

ISBN: 9781597454452

Subjects (MeSH): Pregnancy Complications; Respiratory Tract Diseases - complications

Format: e-Book

Location: Online

Determinants of Minority Mental Health and Wellness

https://libcat.nshealth.ca/en/permalink/provcat29629

edited by Sana Loue, Martha Sajatovic. --New York, NY: Springer Science+Business Media , c2009.

Available Online: View e-Book

Location: Online

Available Online: View e-Book

Author: Loue, Sana

Other Authors: Sajatovic, Martha

Responsibility: edited by Sana Loue, Martha Sajatovic

Place of Publication: New York, NY

Publisher: Springer Science+Business Media

Date of Publication: c2009

ISBN: 9780387756592

Subjects (MeSH): Mental Health - ethnology; Minority Health; Minority Groups - psychology; Psychosocial Support Systems; Social Medicine; Socioeconomic Factors

Other Subjects: United States

Contents: 1. Health and Wellness -- 2. City Living and Mental Health in History -- 3. Mental Health, Mental Health Courts, and Minorities -- 4. Migration and Mental Health -- 5. Media, Minorities, and the Stigma of Mental Illness -- 6. Minority Mental Health and Wellness: A Perspective from Health Care Systems -- 7. Social Support, Mental Health, Minorities, and Acculturative Stress -- 8. Religion and Mental Health Among Minorities and Immigrants in the U.S -- 9. Cultural Considerations Regarding Perspectives on Mental Illness and Healing -- 10. Gender and Minority Mental Health: The Case of Body Image -- 11. Family Determinants of Minority Mental Health and Wellness -- 12. Family-Focused Psychoeducational Programs for Minorities with Serious Mental Illness -- 13. Socioeconomic Status: Risks and Resilience -- 14. Psychiatric Genetics: An Update -- 15. Substance Abuse in Minority Populations -- 16. Neurocognitive Testing of Minorities in Mental Health Settings -- 17. Stress and Resilience -- 18. Methodological Challenges in Research on the Determinants of Minority Mental Health and Wellness.