Search Results - Provincial Hospitals Library Catalogue

Endocrine hypertension : underlying mechanisms and therapy

https://libcat.nshealth.ca/en/permalink/provcat32443

Christian A Koch, George P Chrousos, editors. --New York, NY: Humana Press , c2013.

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Location: Online

The prevalence of hypertension is almost three times as high as that of diabetes mellitus type 2, with both conditions being major risk factors for stroke, ischemic heart disease, cardiac arrhythmias, and heart failure. The exact prevalence of hypertension related to hormonal derangements (endocrine hypertension) is not known but estimated to affect less than 15% of hypertensive patients. Recent scientific discoveries have increased the understanding of the pathophysiologic mechanisms of hypert…

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Other Authors: Koch, Christian A; Chrousos, George P

Responsibility: Christian A Koch, George P Chrousos, editors

Place of Publication: New York, NY

Publisher: Humana Press

Date of Publication: c2013

Physical Description: 1 online resource (xiii, 317 p. : 33 ill., 26 ill. in color)

Series Title: Contemporary endocrinology (Totowa, N.J.)

ISBN: 9781607615484

Subjects (MeSH): Adrenal Gland Diseases - etiology; Hypertension - etiology; Hypertension - therapy

Subjects (LCSH): Obstetrics; Internal medicine; Cardiology; Endocrinology; Nephrology; Urology

Abstract: The prevalence of hypertension is almost three times as high as that of diabetes mellitus type 2, with both conditions being major risk factors for stroke, ischemic heart disease, cardiac arrhythmias, and heart failure. The exact prevalence of hypertension related to hormonal derangements (endocrine hypertension) is not known but estimated to affect less than 15% of hypertensive patients. Recent scientific discoveries have increased the understanding of the pathophysiologic mechanisms of hypertension. In Endocrine Hypertension, a renowned panel of experts provides a comprehensive, state-of-the-art overview of this disorder, discussing when to assign an endocrine cause in one of many conditions that may present with hypertension. The first part of Endocrine Hypertension is dedicated to adrenal causes. The second part of the volume concerns potential nonadrenal causes of hypertension, such as growth hormone excess or deficiency, primary hyperparathyroidism, vitamin D deficiency, testosterone deficiency, insulin resistance, obesity-associated hypertension, and the role of central mineralocorticoid receptors and cardiovascular disease. An important contribution to the literature, Endocrine Hypertension is an indispensable reference not only for endocrinologists, diabetologists, and adrenal investigators, but also for translational scientists and clinicians from cardiology, internal medicine, pediatrics, family medicine, geriatrics, urology, and reproductive medicine / gynecology.

Contents: Part I. Adrenal Hypertension -- Part II. Other Potential Causes of Endocrine Hypertension -- Index.

Format: e-Book

Location: Online

Pediatric endocrinology : a practical clinical guide

https://libcat.nshealth.ca/en/permalink/provcat32587

Sally Radovick, Margaret H. MacGillivray, editors. (2nd ed.) --New York, NY: Humana Press , c2013.

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Location: Online

A state-of-the-art and concise guide to the clinical management of pediatric endocrine disorders, the second edition of the highly regarded Pediatric Endocrinology: A Practical Clinical Guide covers the most common and challenging conditions seen by practicing endocrinologists and primary care physicians, including growth, hypothalamic, pituitary, adrenal, thyroid, calcium and bone, and reproductive disorders, as well as metabolic syndromes. This expanded second edition includes new topics bei…

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Other Authors: Radovick, Sally; MacGillivray, Margaret H

Responsibility: Sally Radovick, Margaret H. MacGillivray, editors

Edition: 2nd ed.

Place of Publication: New York, NY

Publisher: Humana Press

Date of Publication: c2013

Physical Description: 1 online resource (xv, 624 p. : 82 ill., 33 ill. in color)

Series Title: Contemporary endocrinology (Totowa, N.J.)

ISBN: 9781607613954

Subjects (MeSH): Endocrine System Diseases

Subjects (LCSH): Endocrinology; Pediatrics

Abstract: A state-of-the-art and concise guide to the clinical management of pediatric endocrine disorders, the second edition of the highly regarded Pediatric Endocrinology: A Practical Clinical Guide covers the most common and challenging conditions seen by practicing endocrinologists and primary care physicians, including growth, hypothalamic, pituitary, adrenal, thyroid, calcium and bone, and reproductive disorders, as well as metabolic syndromes. This expanded second edition includes new topics being seen more commonly in pediatric endocrinology practices related to obesity and type 2 diabetes mellitus and lipid disorders. Each chapter contains an introductory discussion of the problem, a review of the clinical features that characterize it, the criteria needed to establish a diagnosis, and a comprehensive therapy section delineating the risks and benefits of the best therapeutic options available. Invaluable tables summarize the critical factors in etiology, clinical presentation, diagnosis, and therapeutic dosages. Pediatric Endocrinology: A Practical Clinical Guide, Second Edition, is a comprehensive resource for all clinicians concerned with the myriad endocrinologic disorders seen in children and adolescents

Contents: Part I: Growth Disorders -- Childhood Growth Hormone Deficiency and Hypopituitarism -- Growth Hormone Insensitivity -- Skeletal Dysplasias -- Idiopathic Short Stature -- Growth Hormone Treatment Of The Short Child Born Small For Gestational Age -- Growth Hormone Therapy in Children with Prader-Willi Syndrome -- Turner Syndrome -- Management of Adult with Childhood Onset Growth Hormone Deficiency -- Part II: Hypothalamic and Pituitary Disorders -- Diabetes Insipidus -- Management of Acute and Late Endocrine Effects Following Childhood Cancer Treatment -- Endocrinologic Sequelae of Anorexia Nervosa -- Part III: Adrenal Disorders -- Adrenal Insufficiency -- Congenital Adrenal Hyperplasia -- Cushing Syndrome in Childhood -- Part IV: Thyroid Disorders -- Congenital Hypothyroidism -- Autoimmune Thyroid Disease -- Non-Thyroidal Illness Syndrome -- Resistance to Thyroid Hormone and TSH Receptor Mutations -- Thyroid Neoplasia -- Part V: Mineral and Bone Disorders -- Abnormalities in Calcium Homeostasis -- Rickets: The Skeletal Disorders of Impaired Calcium or Phosphate Availability -- Part VI: Reproductive Disorders and Contraception -- Turner Syndrome, Kallmann Syndrome and Noonan Syndrome -- Precocious Puberty: Clinical Management -- Management of Infants Born with Disorders of Sex Development -- Menstrual Disorders and Hyperandrogenism in Adolescence -- Contraception -- Part VII. Metabolic Disorders -- Hypoglycemia -- Diabetes Mellitus in Children and Adolescents -- Type II Diabetes Mellitus and Obesity in Youth -- Diagnosis and Treatment of Dyslipoproteinemias in Children and Adolescents -- Part VIII: Other Endocrine Disorders -- Autoimmune Endocrine Disorders -- Multiple Endocrine Neoplasia Syndromes -- The Endocrine Response to Critical Illness.

Format: e-Book

Location: Online

Endocrine Disruptors and Puberty

https://libcat.nshealth.ca/en/permalink/provcat30999

Evanthia Diamanti-Kandarakis, Andrea C. Gore, editors. --New York, NY: Humana Press , c2012.

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Location: Online

Endocrine disruption represents one of the most controversial environmental issues of our time. Mounting evidence stemming from more than 10 years of experimental, epidemiological and clinical studies has transformed the once generally discounted subject of endocrine disruptors into an issue of tremendous concern not only within the scientific community but among society as a whole.Following initial evidence from basic research, endocrine disruption in humans has now emerged as a major medical …

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Other Authors: Diamanti-Kandarakis, Evanthia; Gore, Andrea C

Responsibility: Evanthia Diamanti-Kandarakis, Andrea C. Gore, editors

Place of Publication: New York, NY

Publisher: Humana Press

Date of Publication: c2012

Physical Description: 1 online resource (xvii, 378 p. : 18 ill., 11 ill. in color)

Series Title: Contemporary endocrinology (Totowa, N.J.)

ISBN: 9781607615613

Subjects (MeSH): Endocrine Disruptors - adverse effects; Environmental Exposure - adverse effects; Environmental Pollutants - adverse effects; Puberty - drug effects

Subjects (LCSH): Toxicology; Endocrinology

Abstract: Endocrine disruption represents one of the most controversial environmental issues of our time. Mounting evidence stemming from more than 10 years of experimental, epidemiological and clinical studies has transformed the once generally discounted subject of endocrine disruptors into an issue of tremendous concern not only within the scientific community but among society as a whole.Following initial evidence from basic research, endocrine disruption in humans has now emerged as a major medical challenge. In this respect, puberty, a crucial developmental stage, has been definitively identified as a key window of vulnerability with regard to endocrine disruptors. Written by leading authorities in the field, Endocrine Disruptors and Puberty offers an engaging and comprehensive overview of this fascinating and rapidly growing problem. An indispensable resource for all clinicians and scientists interested in this challenging endocrinologic topic, Endocrine Disruptors and Puberty is a timely contribution that will help navigate a path toward understanding the problem and developing solutions.

Contents: Introduction to endocrine disruptors and puberty -- In utero exposure to environmental chemicals: Lessons from maternal cigarette smoking and its effects on gonad development and puberty -- Reproductive neuroendocrine targets of developmental exposure to endocrine disruptors -- Endocrine disruptors and puberty disorders from mice to men (and women) -- Thyroid hormone regulation of mammalian reproductive development and the potential impact of endocrine disrupting chemicals -- Developmental exposure to endocrine disruptors and ovarian function -- Developmental exposure to environmental endocrine disruptors and adverse effects on mammary gland development -- Developmental exposure to endocrine disruptors and male urogenital tract malformations -- EDC exposures and the development of reproductive and non-reproductive behaviors -- Adipocytes as target cells for endocrine disruption -- Altered glucose homeostasis resulting from developmental exposures to endocrine disruptors -- Developmental exposure to endocrine disrupting chemicals: Is there a connection with birth and childhood weights? -- The impact of endocrine disruptors on female pubertal timing -- The influence of endocrine disruptors on male pubertal timing -- Secular trends in pubertal timing: a role for environmental chemical exposure?

Format: e-Book

Location: Online

Ghrelin in Health and Disease

https://libcat.nshealth.ca/en/permalink/provcat31026

Roy G. Smith, Michael O. Thorner, editors. --New York, NY: Humana Press , c2012.

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Location: Online

Ghrelin, the endogenous ligand for the growth hormone secretagogue (GHS) receptor, is critical in the control of food intake and energy balance. The ghrelin receptors are now known to have important physiological properties as modulators of growth hormone release, appetite, glucose homeostasis, metabolism, immune function, neurotransmitter activity, cognitive function and neurodegeneration. Bringing all of this information together in the first comprehensive text on the topic, Ghrelin in Health…

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Other Authors: Smith, Roy G; Thorner, Michael O

Responsibility: Roy G. Smith, Michael O. Thorner, editors

Place of Publication: New York, NY

Publisher: Humana Press

Date of Publication: c2012

Physical Description: 1 online resource (xiv, 290 p. : 44 ill., 3 ill. in color)

Series Vol.: v. 10

Series Title: Contemporary endocrinology (Totowa, N.J.)

ISBN: 9781617799037

Subjects (MeSH): Ghrelin - metabolism; Ghrelin - physiology

Subjects (LCSH): Nutrition; Endocrinology

Abstract: Ghrelin, the endogenous ligand for the growth hormone secretagogue (GHS) receptor, is critical in the control of food intake and energy balance. The ghrelin receptors are now known to have important physiological properties as modulators of growth hormone release, appetite, glucose homeostasis, metabolism, immune function, neurotransmitter activity, cognitive function and neurodegeneration. Bringing all of this information together in the first comprehensive text on the topic, Ghrelin in Health and Disease provides a state-of-the-art synthesis of the latest work in this area for physicians and physician-scientists. This volume addresses the unique property of ghrelin as a modulator of function. Such a property provides potential utility for safe intervention in a wide variety of disease states. Indeed as we learn more about the basic physiology of ghrelin, the potential for treating new disease targets emerge requiring validation in the clinic. Each chapter in this volume is authored by a leading investigator in the field. The introductory chapter sets the background for the book and provides a superb overview of the relevance of ghrelin to physiology, describing how the discovery of ghrelin has prompted us to completely rethink traditional physiology. The authors conclude their chapters by critically addressing the future translational aspects of ghrelin biology and outlining what key basic research and clinical questions remain to be addressed. An invaluable resource, Ghrelin in Health and Disease distinguishes itself as the first comprehensive title covering all of the molecular and clinical issues relating to ghrelin and advancing our clinical understanding of obesity, growth, and reproductive pathogenesis.

Contents: [Machine generated contents note] 1. Ghrelin: A History of Its Discovery / Johannes D. Veldhuis -- 2. Enzymatic Processing of Ghrelin Precursor / Kenji Kangawa -- 3. Ghrelin’s Novel Signaling in Islet ß-Cells to Inhibit Insulin Secretion and Its Blockade As a Promising Strategy to Treat Type 2 Diabetes / Toshihiko Yada -- 4. Gastric Ghrelin in the Regulation of Appetite and Metabolism / Felipe F. Casanueva -- 5. Ghrelin Regulation of AMPK in the Hypothalamus and Peripheral Tissues / Marta Korbonits -- 6. Ghrelin: Neuropeptide Regulator of Metabolism / Michael Alexander Cowley -- 7. GOAT and the Regulation of Energy and Glucose Homeostasis / Jenny Tong -- 8. Ghrelin Regulation of Sleep, Circadian Clock, and Body Temperature / Levente Kapas -- 9. Ghrelin Regulation of Learning, Memory, and Neurodegeneration / Tamas L. Horvath -- 10. Ghrelin Antagonism: A Potential Therapeutic Target for Addictive Behaviour Disorders / Suzanne L. Dickson -- 11. Ghrelin Receptor Agonists in Cachexia of Human Aging / Michael O. Thorner -- 12. Use of Ghrelin and Ghrelin Receptor Agonists in Cancer- and Chemotherapy-Induced Cachexia / Jose M. Garcia -- 13. Ghrelin in Cachexia Associated with End-Stage Renal Disease / Stephen Bloom -- 14. Ghrelin Suppression of Autoimmune Encephalomyelitis / Takashi Yamamura -- 15. Physiological Roles of Des-Acyl Ghrelin / Aart J. van der Lely -- 16. Ghrelin Receptor (GHSR1a), But Not Ghrelin, Is Essential for Dopamine Receptor-2 (DRD2) Agonist-Induced Anorexia / Roy G. Smith.

Format: e-Book

Location: Online

Immunoendocrinology : Scientific and Clinical Aspects

https://libcat.nshealth.ca/en/permalink/provcat29955

edited by George S. Eisenbarth. --Totowa, NJ: Springer Science+Business Media , c2011.

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Location: Online

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Author: Eisenbarth, George S

Responsibility: edited by George S. Eisenbarth

Place of Publication: Totowa, NJ

Publisher: Springer Science+Business Media

Date of Publication: c2011

Series Title: Contemporary endocrinology (Totowa, N.J.)

ISBN: 9781603274784

Subjects (MeSH): Autoimmune Diseases; Autoimmunity; Endocrine System Diseases - immunology; Genetic predisposition to disease

Subjects (LCSH): Immunology; Endocrinology

Format: e-Book

Location: Online

Growth Hormone Related Diseases and Therapy : A Molecular and Physiological Perspective for the Clinician

https://libcat.nshealth.ca/en/permalink/provcat28388

edited by Ken Ho. --Totowa, NJ: Springer Science+Business Media , c2011.

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Location: Online

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Author: Ho, Ken

Responsibility: edited by Ken Ho

Place of Publication: Totowa, NJ

Publisher: Springer Science+Business Media

Date of Publication: c2011

Series Title: Contemporary endocrinology (Totowa, N.J.)

ISBN: 9781607613176

Subjects (MeSH): Human Growth Hormone - physiology; Growth Disorders

Subjects (LCSH): Endocrinology; Developmental biology

Format: e-Book

Location: Online

Cushing's Syndrome : Pathophysiology, Diagnosis and Treatment

https://libcat.nshealth.ca/en/permalink/provcat28924

edited by Marcello D. Bronstein. --Totowa, NJ: Springer Science+Business Media , c2011.

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Location: Online

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Author: Bronstein, Marcello D

Responsibility: edited by Marcello D. Bronstein

Place of Publication: Totowa, NJ

Publisher: Springer Science+Business Media

Date of Publication: c2011

Series Title: Contemporary endocrinology (Totowa, N.J.)

ISBN: 9781603274494

Subjects (MeSH): Cushing Syndrome

Subjects (LCSH): Endocrinology

Format: e-Book

Location: Online

Autoimmune Diseases in Endocrinology

https://libcat.nshealth.ca/en/permalink/provcat28275

edited by Anthony P. Weetman. --Totowa, NJ: Humana Press , c2008.

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Location: Online

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Author: Weetman, Anthony P

Responsibility: edited by Anthony P. Weetman

Place of Publication: Totowa, NJ

Publisher: Humana Press

Date of Publication: c2008

Series Title: Contemporary endocrinology (Totowa, N.J.)

ISBN: 9781597455176

Subjects (MeSH): Autoimmune Diseases; Autoimmunity; Endocrine System Diseases

Subjects (LCSH): Endocrinology; Immunology

Format: e-Book

Location: Online

The Metabolic Syndrome : Epidemiology, Clinical Treatment, and Underlying Mechanisms

https://libcat.nshealth.ca/en/permalink/provcat28488

edited by Barbara Caleen Hansen, George A. Bray. --Totowa, NJ: Humana Press , c2008.

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Location: Online

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Author: Hansen, Barbara Caleen

Other Authors: Bray, George A

Responsibility: edited by Barbara Caleen Hansen, George A. Bray

Place of Publication: Totowa, NJ

Publisher: Humana Press

Date of Publication: c2008

Series Title: Contemporary endocrinology (Totowa, N.J.)

ISBN: 9781603271165

Subjects (MeSH): Metabolic Syndrome X

Subjects (LCSH): Endocrinology; Metabolic diseases

Format: e-Book

Location: Online

Diagnosis and Management of Pituitary Disorders

https://libcat.nshealth.ca/en/permalink/provcat28489

edited by Brooke Swearingen, Beverly M. K. Biller. --Totowa, NJ: Humana Press , c2008.

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Location: Online

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Author: Swearingen, Brooke

Other Authors: Biller, Beverly M. K

Responsibility: edited by Brooke Swearingen, Beverly M. K. Biller

Place of Publication: Totowa, NJ

Publisher: Humana Press

Date of Publication: c2008

Series Title: Contemporary endocrinology (Totowa, N.J.)

ISBN: 9781597452649

Subjects (MeSH): Pituitary Diseases; Pituitary Neoplasms

Subjects (LCSH): Endocrinology

Format: e-Book

Location: Online

Acute Endocrinology : From Cause to Consequence

https://libcat.nshealth.ca/en/permalink/provcat28941

by Greet Berghe. --Totowa, NJ: Humana Press , c2008.

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Location: Online

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Author: Berghe, Greet

Responsibility: by Greet Berghe

Place of Publication: Totowa, NJ

Publisher: Humana Press

Date of Publication: c2008

Series Title: Contemporary endocrinology (Totowa, N.J.)

ISBN: 9781603271776

Subjects (MeSH): Endocrine System Diseases - physiopathology; Endocrinology - methods; Metabolic Diseases - physiopathology; Critical Care - methods

Subjects (LCSH): Critical care medicine; Endocrinology

Format: e-Book

Location: Online

Genomics in Endocrinology : DNA Microarray Analysis in Endocrine Health and Disease

https://libcat.nshealth.ca/en/permalink/provcat29267

edited by Stuart Handwerger, Bruce Aronow. --Totowa, NJ: Humana Press , c2008.

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Location: Online

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Author: Handwerger, Stuart

Other Authors: Aronow, Bruce

Responsibility: edited by Stuart Handwerger, Bruce Aronow

Place of Publication: Totowa, NJ

Publisher: Humana Press

Date of Publication: c2008

Series Title: Contemporary endocrinology (Totowa, N.J.)

ISBN: 9781597453097

Subjects (MeSH): Endocrine Glands - physiology; Endocrine System Diseases - genetics; Endocrinology - methods; Gene expression profiling - methods; Oligonucleotide Array Sequence Analysis - methods

Subjects (LCSH): Genetics; Endocrinology

Format: e-Book

Location: Online

Insulin Resistance and Polycystic Ovarian Syndrome : Pathogenesis, Evaluation, and Treatment

https://libcat.nshealth.ca/en/permalink/provcat30033

edited by Evanthia Diamanti-Kandarakis, John E. Nestler, Dimitrios Panidis, Renato Pasquali. --Totowa, NJ: Humana Press , c2007.

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Location: Online

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Author: Diamanti-Kandarakis, Evanthia

Other Authors: Nestler, John E; Panidis, Dimitrios; Pasquali, Renato

Responsibility: edited by Evanthia Diamanti-Kandarakis, John E. Nestler, Dimitrios Panidis, Renato Pasquali

Place of Publication: Totowa, NJ

Publisher: Humana Press

Date of Publication: c2007

Series Title: Contemporary endocrinology (Totowa, N.J.)

ISBN: 9781597453103

Subjects (MeSH): Insulin Resistance; Polycystic Ovary Syndrome; Metabolic Syndrome X

Subjects (LCSH): Gynecology; Endocrinology

Format: e-Book

Location: Online

Endocrine-Disrupting Chemicals : From Basic Research to Clinical Practice

https://libcat.nshealth.ca/en/permalink/provcat30230

edited by Andrea C. Gore. --Totowa, NJ: Humana Press , c2007.

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Location: Online

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Author: Gore, Andrea C

Responsibility: edited by Andrea C. Gore

Place of Publication: Totowa, NJ

Publisher: Humana Press

Date of Publication: c2007

Series Title: Contemporary endocrinology (Totowa, N.J.)

ISBN: 9781597451079

Subjects (MeSH): Endocrine Disruptors; Endocrine System - physiopathology; Environmental Pollution - adverse effects

Subjects (LCSH): Endocrinology; Chemistry; Environmental Medicine

Format: e-Book

Location: Online

The Leydig Cell in Health and Disease

https://libcat.nshealth.ca/en/permalink/provcat28353

edited by Anita H. Payne, Matthew P. Hardy. --Totowa, NJ: Humana Press , c2007.

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Location: Online

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Author: Payne, Anita H

Other Authors: Hardy, Matthew P

Responsibility: edited by Anita H. Payne, Matthew P. Hardy

Place of Publication: Totowa, NJ

Publisher: Humana Press

Date of Publication: c2007

Series Title: Contemporary endocrinology (Totowa, N.J.)

ISBN: 9781597454537

Subjects (MeSH): Leydig Cells - physiology; Testis - physiology

Subjects (LCSH): Endocrinology; Cytology

Format: e-Book

Location: Online

Hypertension and Hormone Mechanisms

https://libcat.nshealth.ca/en/permalink/provcat28508

edited by Robert M. Carey. --Totowa, NJ: Humana Press , c2007.

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Location: Online

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Author: Carey, Robert M

Responsibility: edited by Robert M. Carey

Place of Publication: Totowa, NJ

Publisher: Humana Press

Date of Publication: c2007

Series Title: Contemporary endocrinology (Totowa, N.J.)

ISBN: 9781592599875

Subjects (MeSH): Autacoids - therapeutic use; Hormones - therapeutic use; Hypertension - physiopathology; Hypertension - therapy

Subjects (LCSH): Cardiology; Endocrinology

Format: e-Book

Location: Online

When Puberty is Precocious : Scientific and Clinical Aspects

https://libcat.nshealth.ca/en/permalink/provcat28784

edited by Ora H. Pescovitz, Emily C. Walvoord. --Totowa: Humana Press , c2007.

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Location: Online

When Puberity is Precocious: Scientific and Clinical Aspects provides a unique continuum of expertise, looking at puberty from anthropologic, epidemiologic, clinical, and molecular perspectives. The volume addresses broad pubertal changes in the general population while at the same time providing in depth information about specific disorders of puberty and the latest management changes. The text is divided into seven parts. The first is an in-depth investigation into neuroendocrine control of p…

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Author: Pescovitz, Ora H

Other Authors: Walvoord, Emily C

Responsibility: edited by Ora H. Pescovitz, Emily C. Walvoord

Place of Publication: Totowa

Publisher: Humana Press

Date of Publication: c2007

Physical Description: 1 online resource (468 p.)

Series Title: Contemporary endocrinology (Totowa, N.J.)

ISBN: 9781597454995 [corrected]

Subjects (MeSH): Puberty, Precocious - etiology; Puberty, Precocious - physiopathology; Psychosexual Development - physiology; Endocrine Disruptors - therapeutic use

Subjects (LCSH): Endocrinology; Pediatrics; Developmental biology

Abstract: When Puberity is Precocious: Scientific and Clinical Aspects provides a unique continuum of expertise, looking at puberty from anthropologic, epidemiologic, clinical, and molecular perspectives. The volume addresses broad pubertal changes in the general population while at the same time providing in depth information about specific disorders of puberty and the latest management changes. The text is divided into seven parts. The first is an in-depth investigation into neuroendocrine control of puberty, the second looks at secular trends and the onset of puberty, and the third provides an examination into isolated breast development. The fourth section covers adrenal abnormalities and puberty, the next two sections include chapters on gonadotropinÇÖs effects, and the final section is a looks at environmental effects on puberty. Comprehensive and timely, When Puberity is Precocious: Scientific and Clinical Aspects will become an essential reference for endocrinologists and internists with an interest in precocious puberty.

Contents: 1. Control puberty in rodents : special focus on the female / Sabine Heger and Sergio R. Ojeda -- 2. Control of puberty in non-human primates / Tony M. Plant -- 3. Control of puberty in humans / Dennis M. Styne and Melvin M. Grumbach -- 4. Genetic regulation of the variation in pubertal timing / Craig A. Hodges and Mark R. Palmert -- 5. Puberty is starting earlier in the 21st century / Marcia E. Herman-Giddens -- 6. BMI and the onset of puberty / Paul Kaplowitz -- 7. Puberty timing remains unchanged / Peter A. Lee and Christopher P. Houk -- 8. Premature thelarche / Linda A. DiMeglio and Adda Grimberg -- 9. Gynecomastia : epidemiology, pathophysiology, and management / Samar N. Rahhal and John S. Fuqua -- 10. Premature adrenarche : harbingers and consequences / Alicia Belgorosky, Maria Sonia Baquedano, Gabriela Guercio and Marco A. Rivarola -- 11. Pubertal consequences of being born small for gestational age / Dyanne A. Wilson, Wayne S. Cutfield and Paul L. Hofman -- 12. Congenital adrenal hyperplasia / Lenore S. Levine, Sharon E. Oberfield and Lauren Antler -- 13. Polycystic ovary syndrome in the peripubertal period / Selma Feldman Witchel -- 14. Psychological and social problems in children with premature adrenarche and precocious puberty / Lorah D. Dorn -- 15. Etiology of gonadotropin-dependent precocious puberty / Erik A. Imel and Kathleen R. Bethin -- 16. Treatment of gonadotropin-dependent precocious puberty / Zeina M. Nabhan and Emily C. Walvoord -- 17. McCune-Albright syndrome : pathophysiology, diagnosis, and management / Tamara S. Hannon and Erica A. Eugster -- 18. Familial male-limited precocious puberty / Nerissa C. Kreher -- 19. Gonadal and adrenal tumors / Inessa M. Gelfand, MD and Nadine G. Haddad -- 20. The Role of Endocrine Disruptors in Pubertal Development / Todd D. Nebesio, MD and Ora H. Pescovitz -- 21. Precocious puberty in internationally adopted girls / Grete Teilmann, Anne-Simone Parent, Niels E. Skakkebtek and Jean-Pierre Bourguignon.