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Pediatric Forensic Evidence : A Guide for Doctors, Lawyers and Other Professionals

https://libcat.nshealth.ca/en/permalink/provcat41537
David L. Robinson. --Cham: Springer , 2017.
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This book provides guidance to all professionals working with children who present with injuries, neglect, illness falsification and other forms of child abuse. Clinical findings and the current literature are analyzed. The author’s clinical experience is shared to assist the reader in diagnosing the cause of injury and other presentations. This text is the result of many years of experience in the UK working with children in an East London hospital (which receives over 1000 children a week thr…
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Author
Robinson, David L
Responsibility
David L. Robinson
Place of Publication
Cham
Publisher
Springer
Date of Publication
2017
Physical Description
1 online resource (xviii, 216 pages) : 18 illus. in color
ISBN
9783319453378
9783319453354 (print ed.)
Subjects (MeSH)
Forensic Medicine
Pediatrics
Social Work
Child Abuse - diagnosis
Child Abuse, Sexual - diagnosis
Abstract
This book provides guidance to all professionals working with children who present with injuries, neglect, illness falsification and other forms of child abuse. Clinical findings and the current literature are analyzed. The author’s clinical experience is shared to assist the reader in diagnosing the cause of injury and other presentations. This text is the result of many years of experience in the UK working with children in an East London hospital (which receives over 1000 children a week through the children’s Emergency Department) and the analysis of over 400 cases for the Family and Crown Courts. Mainstream opinions, the medical literature, and examples from extensive experience on the wards and in Court are discussed. Pediatric Forensic Evidence is aimed at doctors, lawyers, the Courts, social workers, health visitors, teachers, the police and others, guiding them through the analysis of injury and when to raise concerns.
Contents
1. General Aspects of Child Protection -- 2. Bruising in Infants & Children -- 3. Fractures -- 4. Burns -- 5. Abusive Head Trauma (AHT) -- 6. Abdominal and Thoracic Trauma -- 7. Neglect and Emotional Abuse -- 8. Fabricated or Induced Illness by Carers (FII) -- Child Sexual Abuse.
Format
e-Book
Location
Online
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Essentials of Autopsy Practice : Reviews, Updates, and Advances

https://libcat.nshealth.ca/en/permalink/provcat41573
Guy N. Rutty, editor. --Cham: Springer , 2017.
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This book covers topical subjects within the field of death investigation, where changes in practice have recently occurred. As the area of dating of wounds has changed since the subject was addressed in a previous volume, this subject is revisited for the first time. The remaining subjects covered in this volume embrace the multi-disciplinary approach required for death investigation, and address advances in the field of forensic radiology imaging, pathology, and toxicology. There is also a ch…
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Other Authors
Rutty, Guy N
Responsibility
Guy N. Rutty, editor
Place of Publication
Cham
Publisher
Springer
Date of Publication
2017
Physical Description
1 online resource (x, 182 pages) : 60 illus., 49 illus. in color
Series
Essentials of Autopsy Practice
ISBN
9783319469973
9783319469966 (print ed.)
Subjects (MeSH)
Autopsy - methods
Forensic Medicine
Abstract
This book covers topical subjects within the field of death investigation, where changes in practice have recently occurred. As the area of dating of wounds has changed since the subject was addressed in a previous volume, this subject is revisited for the first time. The remaining subjects covered in this volume embrace the multi-disciplinary approach required for death investigation, and address advances in the field of forensic radiology imaging, pathology, and toxicology. There is also a chapter on cardiopulmonary resuscitation which explains clinical processes and procedures that may occur to an individual immediately before death that may have a bearing on the subsequent autopsy findings. Essentials of Autopsy Practice: Reviews, Updates and Advances is an educational and practical resource aimed at trainees and consultants, generalists and specialists, and the new multi-disciplinary team alike.
Contents
The role of cross-sectional imaging in the investigation of childhood deaths -- Vertebral artery trauma -- Death in crowds -- New psychoactive substances -- Horse related injuries and deaths -- Cardiopulmonary resuscitation -- The dating of injury; the five step approach. A clinical method to enlighten forensic aspects.
Format
e-Book
Location
Online
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Color atlas of pathophysiology

https://libcat.nshealth.ca/en/permalink/provcat42055
Stefan Silbernagl, Florian Lang ; 195 color plates by Rüdiger Gay and Astried Rothenburger ; translator, Geraldine O'Sullivan. (3rd edition) --Stuttgart: Thieme , c2016.
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Online
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Author
Silbernagl, Stefan
Other Authors
Lang, Florian, 1945-
Responsibility
Stefan Silbernagl, Florian Lang ; 195 color plates by Rüdiger Gay and Astried Rothenburger ; translator, Geraldine O'Sullivan
Edition
3rd edition
Alternate Title
Colour atlas of pathophysiology
Pathophysiology
Place of Publication
Stuttgart
Publisher
Thieme
Date of Publication
c2016
Physical Description
1 online resource (x, 438 pages) : illustrations
ISBN
9783131165534
9783131490636 (eISBN)
Subjects (MeSH)
Pathology
Physiological Phenomena
Specialty
Pathology
Physiology
Contents
Fundamentals -- Temperature, energy -- Blood -- Kidney, salt and water balance -- Stomach, intestines, liver -- Heart and circulation -- Metabolic disorders -- Hormones -- Neuromuscular and sensory systems.
Format
e-Book
Publication Type
Atlas
Location
Online
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Walter L. Kemp, Travis Brown. --New York, NY: Thieme , c2018.
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Online
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Author
Kemp, Walter L.
Other Authors
Brown, Travis G.
Responsibility
Walter L. Kemp, Travis Brown.
Alternate Title
Thieme test prep for the USMLE® : pathology Q&A
Pathology Q & A
Pathology questions & answers
Pathology questions and answers
Place of Publication
New York, NY
Publisher
Thieme
Date of Publication
c2018
Physical Description
1 online resource
Series
Thieme test prep for the USMLE
ISBN
9781626233805
9781626233812 (eISBN)
Subjects (MeSH)
Pathologic Processes
Specialty
Pathology
Contents
Cell injury, adaptations, and death -- Inflammation and repair -- Hemodynamics -- Diseases of the immune system -- Neoplasia -- Genetic and pediatric diseases -- Environmental and nutritional disease -- Diseases of the cardiovascular system -- Diseases of the hematopoietic and lymphoid systems -- Diseases of the respiratory system -- Diseases of the kidney and urinary tract -- Diseases of the mouth and gastrointestinal tract -- Diseases of the liver, gallbladder, and biliary tract -- Diseases of the pancreas -- Diseases of the male and female genital tract -- Diseases of the breast -- Diseases of the endocrine system -- Diseases of the musculoskeletal system -- Diseases of the peripheral and central nervous systems -- Diseases of the skin -- Mixed items -- Images.
Format
e-Book
Publication Type
Examination Questions
Location
Online
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Human pathology : case reports

https://libcat.nshealth.ca/en/permalink/provcat42121
Elsevier
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Holdings
Vol 1, 2014 -
Location
Online
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Publisher
Elsevier
Holdings
Vol 1, 2014 -
Publication Frequency
Quarterly
ISSN
2214-3300
Specialty
Pathology
Format
e-Journal
Location
Online
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Structural heart cases : a color atlas of pearls and pitfalls

https://libcat.nshealth.ca/en/permalink/provcat42172
Paul Sorajja. --Philadelphia, PA: Elsevier , c2019.
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Using a practical, case-based format, this superbly illustrated atlas by Dr. Paul Sorajja is a comprehensive collection of more than 130 professional experiences in treating structural heart disease. Organized by pathology, each case presents key clinical points for practitioners at all levels, from beginner to expert. Cases are provided by interventionalists and surgeons with extensive hands-on experience, and edited by experts in the field.
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Other Authors
Sorajja, Paul
Responsibility
Paul Sorajja
Alternate Title
A colour atlas of pearls & pitfalls
Place of Publication
Philadelphia, PA
Publisher
Elsevier
Date of Publication
c2019
Physical Description
1 online resource, 318 p.
ISBN
9780323546959
Subjects (MeSH)
Cardiovascular Surgical Procedures
Heart Diseases
Specialty
Cardiology
Cardiovascular Surgical Procedures
Pathology
Abstract
Using a practical, case-based format, this superbly illustrated atlas by Dr. Paul Sorajja is a comprehensive collection of more than 130 professional experiences in treating structural heart disease. Organized by pathology, each case presents key clinical points for practitioners at all levels, from beginner to expert. Cases are provided by interventionalists and surgeons with extensive hands-on experience, and edited by experts in the field.
Access
Registration required for PDF access.
Format
e-Book
Publication Type
Atlas
Case Reports
Location
Online
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Natural Orifice Specimen Extraction Surgery : Colorectal Cancer

https://libcat.nshealth.ca/en/permalink/provcat42527
Xishan Wang, editor. --Singapore: Springer , c2018.
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This introduces the theoretical and practical guide of NOSES. The book introduced 10 different techniques of NOSES for colorectal neoplasms based on extensive high-quality surgical images. The first part mainly describes the development process of NOSES and the current achievements of these techniques which will provide readers a general understanding of NOSES. The second part elaborates on ten different surgical procedures specific to position of tumor location of NOSES in detail. All key tech…
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Other Authors
Wang, Xishan
Responsibility
Xishan Wang, editor
Place of Publication
Singapore
Publisher
Springer
Date of Publication
c2018
Physical Description
1 online resource (xxii, 173 p.) : 626 illus., 618 illus. in color
ISBN
9789811304668
9789811304651 (print ed.)
9789811304675 (print ed.)
Subjects (MeSH)
Colorectal Neoplasms - surgery
Minimally Invasive Surgical Procedures
Natural Orifice Endoscopic Surgery - methods
Surgical Oncology - methods
Specialty
Pathology
Surgical Oncology
Abstract
This introduces the theoretical and practical guide of NOSES. The book introduced 10 different techniques of NOSES for colorectal neoplasms based on extensive high-quality surgical images. The first part mainly describes the development process of NOSES and the current achievements of these techniques which will provide readers a general understanding of NOSES. The second part elaborates on ten different surgical procedures specific to position of tumor location of NOSES in detail. All key technical points and operational skills regarding to NOSES are displayed by both high-quality images. The indications and contraindications are also strictly determined in this book. In addition to the elaboration of NOSES, each chapter of this book also conduct a detailed and comprehensive analysis the hot spots, technical difficulties and key issues with regard to laparoscopic surgery for colorectal cancer. This book is suitable for the colorectal cancer surgeons and doctors of general surgery.
Contents
Overview of NOTES and NOSES for Colorectal Cancer -- Perioperative Preparation of NOSES for Colorectal Cancer -- Laparoscopic Lower Rectal Cancer Resection with Transanal Specimen Extraction (NOSES IA and NOSES IB) -- Laparoscopic Middle Rectal Cancer Resection with Transanal Specimen Extraction (NOSES II) -- Laparoscopic Middle Rectal Cancer Resection with Transvaginal Specimen Extraction (NOSES III) -- Laparoscopic Upper Rectal Cancer Resection with Transanal Specimen Extraction (NOSES IV) -- Laparoscopic Upper Rectal Cancer Resection with Transvaginal Specimen Extraction (NOSES V) -- Laparoscopic Left Colon Cancer Resection with Transanal Specimen Extraction (NOSES VI) -- Laparoscopic Left Colon Cancer Resection with Transvaginal Specimen Extraction (NOSES VII) -- Laparoscopic Right Colon Cancer Resection with Transvaginal Specimen Extraction (NOSES VIII) -- Laparoscopic Total Colectomy with Transanal Specimen Extraction (NOSES IX) -- Laparoscopic Total Colectomy with Transvaginal Specimen Extraction (NOSES X) -- Prevention and Treatment of Common Complications of NOSES in Colorectal Cancer.
Format
e-Book
Location
Online
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Damage-Associated Molecular Patterns in Human Diseases : Volume 1. Injury-Induced Innate Immune Responses

https://libcat.nshealth.ca/en/permalink/provcat42536
Walter Gottlieb Land. --Cham: Springer , c2018.
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This book presents current understanding of the importance of modern immunology in the etiopathogenesis of human diseases and explores how this understanding is impacting on diagnosis, prognosis, treatment, and prophylaxis. As the core of modern immunology, the "danger/injury model" is introduced and addressed throughout the book. Volume I of the book describes the network of damage-associated molecular pattern molecules (DAMPs) and examines the central role of DAMPs in cellular stress response…
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Author
Land, Walter Gottlieb
Responsibility
Walter Gottlieb Land
Alternate Title
Injury-induced innate immune responses
Place of Publication
Cham
Publisher
Springer
Date of Publication
c2018
Physical Description
1 online resource (xlviii, 870 p.) : 115 illus., 102 illus. in color
ISBN
9783319786551
9783319786544 (print ed.)
9783319786568 (print ed.)
Subjects (MeSH)
Biomarkers - analysis
Immunologic Techniques
Molecular Medicine
Pathogen-Associated Molecular Pattern Molecules
Stress, Physiological - immunology
Wounds and Injuries - immunology
Specialty
Diagnosis
Molecular Medicine
Pathology
Abstract
This book presents current understanding of the importance of modern immunology in the etiopathogenesis of human diseases and explores how this understanding is impacting on diagnosis, prognosis, treatment, and prophylaxis. As the core of modern immunology, the "danger/injury model" is introduced and addressed throughout the book. Volume I of the book describes the network of damage-associated molecular pattern molecules (DAMPs) and examines the central role of DAMPs in cellular stress responses and associated regulated cell death, the promotion and resolution of inflammation, the activation of innate lymphoid cells and unconventional T cells, the stimulation of adaptive immunity, and tissue repair. The significance of DAMPs in a wide range of human diseases will then be explored in Volume II of the book, with discussion of the implications of injury-induced innate immunity for present and future treatments. This book is written for professionals from all medical and paramedical disciplines who are interested in the introduction of innovative data from immunity and inflammation research into clinical practice. The readership will include practitioners and clinicians such as hematologists, rheumatologists, traumatologists, oncologists, intensive care anesthetists, endocrinologists such as diabetologists, psychiatrists, neurologists, pharmacists, and transplantologists.
Contents
Part I. The Three Major Paradigms in Modern Immunology -- Prologue: The Term "Immunity" over the Course of Time -- The Three Major Paradigms in Immunology -- Epilogue: What Major Paradigm in Immunology Comes Next? -- Part II. The Innate Immune System: an Organ of Perception Determined to Maintain Homeostasis -- Prologue: The Guardians of Homeostasis -- Innate Immune Recognition Molecules -- Epilogue: The Innate Immune System: a Global Player in Health and Disease -- Part III. The Whole Family of Mammalian Innate Immune Cells -- Prologue: The Whole Body as an Immune System? -- Mobile Innate Immune Cells -- Sessile Innate Immune Cells -- Epilogue: The Whole Body as an Immune Defence System -- Part IV. The World of DAMPs. Prologue: About DAMPs, PAMPs and MAMPs -- Endogenous DAMPs, Category I: Constitutively Expressed Native Molecules (Cat. I DAMPs) -- Endogenous DAMPs, Category II: Constitutively Expressed, Injury-Modified Molecules (Cat. II DAMPs) -- Endogenous DAMPs, Category III: Inducible DAMPs (Cat. III DAMPs) -- Exogenous DAMPs, Category IV (Cat. IV DAMPs) -- Epilogue: The Well-Dosed Work of DAMPs in their Commission to Restore and Maintain Homeostasis -- Part V. Cellular Stress Responses and Regulated Cell Death -- Prologue: Innate Immune Tools to Defend against Stressful Injury: Success and Failure -- Cell-Autonomous (Cell-Intrinsic) Stress Responses -- Regulated Cell Death -- Epilogue: The Horror of an Injury-Induced Avalanche of DAMPs -- Part VI. Innate Immune Effector Responses -- Prologue: The Various Facets of Innate Immune Effector Responses -- Cellular Inflammatory Responses -- Humoral Innate Immune Effector Responses -- Regulation of Innate Inflammatory Responses -- Epilogue to Part VI -- Part VII. Function of Innate Lymphoid Cells and Unconventional T Cells with Partial Innate Function -- Prologue: The "Ready-to-Go" Lymphocytes of the Immune System -- Activating and Function of Innate Lymphoid Cells -- Activating and Function of Unconventional T Cells -- Epilogue: Killer Lymphocytes as Tools for Future Immunotherapeutic Approaches -- Part VIII. DAMPs Promoting Adaptive Immunity and Tissue Repair -- Prologue: The "Long Arm" of DAMPs in Shaping Adaptive Immune Responses and Tissue Repairing Processes -- Antigen Uptake, Processing and Presentation by Dendritic Cells -- Antigen in the Presence of DAMPs Induces Immunostimulatory Dendritic Cells to Promote "Destructive" Acquired Immune Responses -- Antigen in the Absence of DAMPs Promotes Immunotolerance: the Role of Dendritic Cells and Regulatory T Cells -- An Impressive Example of Peripheral Tolerance against Nonself: Tolerance to Commensal Bacterial and Dietary Protein Antigens -- Immunometabolism of Dendritic Cells and T Cells -- Role of DAMPs in Tissue Regeneration and Repair -- Epilogue: DAMPs as Key Players in the Pathogenesis of Many Human Diseases.
Format
e-Book
Location
Online
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Atlas of Non-Gynecologic Cytology

https://libcat.nshealth.ca/en/permalink/provcat42602
Xin Jing, Momin T. Siddiqui, Qing Kay Li, editors. --Cham: Springer , c2018.
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This text focuses on all aspects of non-gynecologic cytopathology, from key features of benign and malignant lesions, to diagnostic pearls and ancillary testing. Although this book is written by multiple authors, all chapters follow a similar format: brief introduction of the specific organ/system (including types of specimens and techniques to obtain samples), description of normal findings, and a practical approach to diagnose benign and malignant lesions. Key cytomorphological features, curr…
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Other Authors
Jing, Xin
Siddiqui, Momin T.
Li, Qing Kay
Responsibility
Xin Jing, Momin T. Siddiqui, Qing Kay Li, editors
Place of Publication
Cham
Publisher
Springer
Date of Publication
c2018
Physical Description
1 online resource (xv, 299 p.) : 583 illus. in color
Series Title
Atlas of anatomic pathology
ISBN
9783319896748
9783319896731 (print ed.)
9783319896755 (print ed.)
ISSN
2625-3372
Subjects (MeSH)
Cytodiagnosis
Specialty
Cell Biology
Clinical Laboratory Techniques
Pathology
Abstract
This text focuses on all aspects of non-gynecologic cytopathology, from key features of benign and malignant lesions, to diagnostic pearls and ancillary testing. Although this book is written by multiple authors, all chapters follow a similar format: brief introduction of the specific organ/system (including types of specimens and techniques to obtain samples), description of normal findings, and a practical approach to diagnose benign and malignant lesions. Key cytomorphological features, current terminology and molecular diagnostic tests are also highlighted within this volume. The Atlas of Non-Gynecologic Cytology is a practical resource for cytotechnologists, cytopathologists, and pathologists who are practicing general surgical pathology and cytopathology. The book is also a valued text for medical students, residents, fellows, and other allied health personnel who take care and/or treat patients based on the histological diagnosis of diseases.
Contents
Salivary Gland Fine Needle Aspiration,- Thyroid Fine Needle Aspiration Cytology -- Breast Cytology -- Pulmonary Cytology -- Gastrointestinal Cytology -- Pancreaticobiliary Tract Cytology -- Liver Cytology -- Kidney and Adrenal Gland Cytology -- Urine Cytology -- Serous Effusion Cytology -- Lymph Node Cytology.
Format
e-Book
Publication Type
Atlas
Location
Online
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Pathology of the Pleura and Mediastinum

https://libcat.nshealth.ca/en/permalink/provcat42610
Timothy Craig Allen, Saul Suster, editors. --Cham: Springer , c2018.
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This book covers the complete field of pleura and mediastinum pathology - from acquired multilocular thymic cyst to well-differentiated papillary mesothelioma. The alphabetically arranged entries, each of which provides a detailed description of a specific pathological disease pattern, allow readers to quickly and easily find the information they need.
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Other Authors
Allen, Timothy Craig
Suster, Saul
Responsibility
Timothy Craig Allen, Saul Suster, editors
Place of Publication
Cham
Publisher
Springer
Date of Publication
c2018
Physical Description
1 online resource (xviii, 475 p.) : 406 illus., 402 illus. in color
Series Title
Springer reference
Encyclopedia of pathology
ISBN
9783319667966
9783319667959 (print ed.)
ISSN
2366-6269
Subjects (MeSH)
Pleura - pathology
Mediastinum - pathology
Pleural Diseases - Encyclopedias
Mediastinal Diseases - Encyclopedias
Specialty
Pathology
Pulmonary Medicine
Notes
"eReference"--Publisher.
Abstract
This book covers the complete field of pleura and mediastinum pathology - from acquired multilocular thymic cyst to well-differentiated papillary mesothelioma. The alphabetically arranged entries, each of which provides a detailed description of a specific pathological disease pattern, allow readers to quickly and easily find the information they need.
Format
e-Book
Location
Online
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Precision Molecular Pathology of Neoplastic Pediatric Diseases

https://libcat.nshealth.ca/en/permalink/provcat42616
Larissa V. Furtado, Aliya N. Husain, editors. --Cham: Springer , c2018.
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Online
This book provides a comprehensive, state-of-the art review of pediatric oncology. The text covers relevant concepts in molecular biology and addresses technical principles, applications, challenges, and integration of current and emerging genomic and molecular methods in the diagnosis and personalized management of childhood cancers. The text also discusses a wide array of pediatric neoplasms in the context of molecular pathology in a concise and understandable manner, with focus on their mole…
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Other Authors
Furtado, Larissa V.
Husain, Aliya N.
Responsibility
Larissa V. Furtado, Aliya N. Husain, editors
Place of Publication
Cham
Publisher
Springer
Date of Publication
c2018
Physical Description
1 online resource (viii, 360 p.) : 64 illus., 63 illus. in color
Series Title
Molecular pathology library
ISBN
9783319896267
9783319896250 (print ed.)
9783319896274 (print ed.)
ISSN
1935-987X
Subjects (MeSH)
Child
Neoplasms - pathology
Pathology, Molecular - methods
Precision Medicine - methods
Specialty
Medical Oncology
Molecular Medicine
Pathology
Pediatrics
Precision Medicine
Abstract
This book provides a comprehensive, state-of-the art review of pediatric oncology. The text covers relevant concepts in molecular biology and addresses technical principles, applications, challenges, and integration of current and emerging genomic and molecular methods in the diagnosis and personalized management of childhood cancers. The text also discusses a wide array of pediatric neoplasms in the context of molecular pathology in a concise and understandable manner, with focus on their molecular pathogenesis, clinicopathological features, classification, molecular diagnosis, and approaches to personalized care. Written by experts in the field, Precision Molecular Pathology of Neoplastic Pediatric Diseases serves as a valuable resource for pathologists, pediatric oncologists, trainees and researchers with an interest in pediatric and molecular pathology.
Contents
Part I. Molecular Pathology of Pediatric Neoplasms: General Principles -- 1. Principles of Molecular Biology and Oncogenesis -- 2. Molecular Methods in Oncology: Targeted Mutational Analysis -- 3. Molecular Methods in Oncology: Genomic Analysis -- 4. Molecular Testing in Pediatric Oncology Practice -- 5. Molecular Targeted Therapy of Pediatric Neoplasms -- Part II. Molecular Pathology of Specific Pediatric Neoplasms -- 6. Hematolymphoid System -- 7. Pediatric Brain Tumors -- 8. Neuroblastoma and Neuroblastic Tumors -- 9. Soft Tissue and Bone Neoplasms -- 10. Skin, Melanocytic Neoplasms -- 11. Salivary Gland, Thyroid, and Parathyroid Neoplasms: Molecular Features -- 12. Cardiovascular and Respiratory Systems -- 13. Gastrointestinal Tract -- 14. Liver and Pancreas -- 15. Molecular Pathology of Pediatric Renal Tumors.
Format
e-Book
Location
Online
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Pathology of Female Cancers : Precursor and Early-Stage Breast, Ovarian and Uterine Carcinomas

https://libcat.nshealth.ca/en/permalink/provcat42622
Takuya Moriya, editor. --Singapore: Springer , c2018.
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Online
This book focuses on precursor lesions, borderline lesions, and early carcinomas of female-specific organs from the standpoint of pathology. In 2012, the latest WHO Classification of Tumours of the Breast, 4th ed., was published and subsequently, in 2014, the WHO Classification of Tumours of Female Reproductive Organs, 4th ed., was published. In these fourth editions, several new concepts are addressed that were not described in the previous editions, and many of them are related to the awarene…
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Other Authors
Moriya, Takuya
Responsibility
Takuya Moriya, editor
Place of Publication
Singapore
Publisher
Springer
Date of Publication
c2018
Physical Description
1 online resource (vii, 91 p.) : 73 illus. in color
ISBN
9789811086069
9789811086052 (print ed.)
9789811086076 (print ed.)
Subjects (MeSH)
Breast Neoplasms - pathology
Diagnosis, Differential
Early Detection of Cancer
Genital Neoplasms, Female - pathology
Specialty
Gynecology
Medical Oncology
Pathology
Abstract
This book focuses on precursor lesions, borderline lesions, and early carcinomas of female-specific organs from the standpoint of pathology. In 2012, the latest WHO Classification of Tumours of the Breast, 4th ed., was published and subsequently, in 2014, the WHO Classification of Tumours of Female Reproductive Organs, 4th ed., was published. In these fourth editions, several new concepts are addressed that were not described in the previous editions, and many of them are related to the awareness of the specific pathogenesis of tumors in female patients. Although some of these issues are still controversial, several paradigm shifts should be understood by medical scientists. Thus researchers, diagnostic pathologists, and clinicians must share current information about what is taking place in the field and what the next issue to resolve is. This volume greatly broadens the reader's understanding of the new concepts and paradigm shifts, as it includes informationon how to diagnose and make differential diagnoses on a practical basis and also provides a thorough explanation of the molecular-clinicopathologic basis of the new concepts. The book thus benefits gynecologists, breast surgeons, gynecologic-medical oncologists, and cytotechnologists.
Contents
A new strategy for diagnosis of squamous intraepithelial neoplasia of the uterine cervix -- Adenocarcinoma and its precursor of the uterine cervix: current concept -- Heterogeneity of the precursor lesions of endometrial carcinoma, according to the histologic subtype -- Current concept of precancerous and early stage of serous ovarian carcinoma -- Ovarian carcinomas associated with endometriosis -- Problems with the histological diagnosis of epithelial borderline tumors of the ovary -- Development of breast carcinoma in relation to the intrinsic subtype -- Risk assessments of breast cancer occurrence, by morphological and molecular approach.
Format
e-Book
Location
Online
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Practical Atlas of Breast Pathology

https://libcat.nshealth.ca/en/permalink/provcat42652
Simona Stolnicu, Isabel Alvarado-Cabrero, editors. --Cham: Springer , c2018.
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Online
This book presents the basic concepts for understanding and practicing breast pathology in routine practice. It explains how to tackle the diagnosis, emphasizing diagnostic clues for each entity as well as pitfalls and mimickers. Each chapter has concise, relevant text illustrated by numerous high-quality pictures highlighting the pearls and challenges in the diagnosis of breast lesions. Experts from around the world describe common and rarer conditions affecting the breast. Histology, immunohi…
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Other Authors
Stolnicu, Simona
Alvarado-Cabrero, Isabel
Responsibility
Simona Stolnicu, Isabel Alvarado-Cabrero, editors
Place of Publication
Cham
Publisher
Springer
Date of Publication
c2018
Physical Description
1 online resource (xvi, 511 p.) : 959 illus., 941 illus. in color
ISBN
9783319932576
9783319932569 (print ed.)
9783319932583 (print ed.)
Subjects (MeSH)
Breast Diseases - diagnosis
Breast Diseases - pathology
Breast Neoplasms - diagnosis
Breast Neoplasms - pathology
Specialty
Gynecology
Pathology
Abstract
This book presents the basic concepts for understanding and practicing breast pathology in routine practice. It explains how to tackle the diagnosis, emphasizing diagnostic clues for each entity as well as pitfalls and mimickers. Each chapter has concise, relevant text illustrated by numerous high-quality pictures highlighting the pearls and challenges in the diagnosis of breast lesions. Experts from around the world describe common and rarer conditions affecting the breast. Histology, immunohistochemistry, cytology, radiology and key morphologic criteria are covered. The book includes a chapter dedicated to breast normal histology, which is very important for understanding breast pathology, and a separate chapter for breast radiology, which is essential in understanding and diagnosing the breast lesions especially in a multidisciplinary team. Also, there is a chapter with the latest TNM staging system as well as the recently revised World Health Organization classification of breast tumors. Since in many breast units the cytology is still used to diagnose breast lesions there is a chapter dedicated to this technique. This book is aimed at trainees and practicing pathologists in surgical pathology, particularly those with an interest in breast pathology and those tackling the daily sign-out.
Contents
Histology of the normal breast -- Radiology of the normal breast and the BIRADS system -- Inflammatory lesions of the breast -- Lesions of the breast with uncertain etiology -- Benign epithelial lesions of the breast -- Myoepithelial lesions of the breast -- Classification of the breast carcinoma -- Benign tumors of the breast -- Ductal in situ carcinoma -- Lobular neoplasia -- Microinvasive carcinoma -- Infiltrating carcinoma of the breast -- Special types of invasive breast carcinoma -- Staging of the breast carcinoma -- Prognostic and predictive factors in breast carcinoma -- Morphologic changes induces by the oncologic treatment for breast carcinoma -- Mesenchymal lesions of the breast -- Fibroepithelial lesions of the breast -- Hematopoietic lesions of the breast -- Lesions of the nipple -- Breast lesions in male -- Core needle biopsy interpretation -- The role of immunohistochemistry in breast pathology -- "Basic" molecular biology in breast carcinoma -- Breast lesions in children -- Metastatic tumors to the breast -- Sampling the breast surgical specimens -- The role of cytopathology in the modern diagnosis of breast pathology.
Format
e-Book
Publication Type
Atlas
Location
Online
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Introduction to Statistical Methods in Pathology

https://libcat.nshealth.ca/en/permalink/provcat42659
Amir Momeni, Matthew Pincus, Jenny Libien. --Cham: Springer , c2018.
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This text provides a comprehensive and practical review of the main statistical methods in pathology and laboratory medicine. It introduces statistical concepts used in pathology and laboratory medicine. The information provided is relevant to pathologists both for their day to day clinical practice as well as in their research and scholarly activities. The text will begins by explaining the fundamentals concepts in statistics. In the later sections, these fundamental concepts are expanded and …
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Author
Momeni, Amir
Other Authors
Pincus, Matthew
Libien, Jenny
Responsibility
Amir Momeni, Matthew Pincus, Jenny Libien
Place of Publication
Cham
Publisher
Springer
Date of Publication
c2018
Physical Description
1 online resource (xiv, 317 p.) : 84 illus. in color
ISBN
9783319605432
9783319605425 (print ed.)
9783319605449 (print ed.)
9783319868837 (print ed.)
Subjects (MeSH)
Clinical Laboratory Techniques
Data Interpretation, Statistical
Medical Laboratory Science
Pathology, Clinical - methods
Statistics as Topic
Specialty
Data Science
Pathology
Abstract
This text provides a comprehensive and practical review of the main statistical methods in pathology and laboratory medicine. It introduces statistical concepts used in pathology and laboratory medicine. The information provided is relevant to pathologists both for their day to day clinical practice as well as in their research and scholarly activities. The text will begins by explaining the fundamentals concepts in statistics. In the later sections, these fundamental concepts are expanded and unique applications of statistical methods in pathology and laboratory medicine practice are introduced. Other sections of the text explain research methodology in pathology covering a broad range of topics from study design to analysis of data. Finally, data-heavy novel concepts that are emerging in pathology and pathology research are presented such as molecular pathology and pathology informatics. Introduction to Statistical Methods in Pathology will be of great value for pathologists, pathology residents, basic and translational researchers, laboratory managers and medical students.
Contents
1. Why Every Pathologist Needs to Know Statistics -- 2. Assessing Diagnostic Tests -- 3. Probability and Probability Distribution -- 4. Linear Correlations -- 5. Cross Tabulation and Categorical Data Analysis -- 6. Comparing Sample Means -- 7. Multivariate Analysis -- 8. Imputation and Missing Data -- 9. Survival Analysis -- 10. Validation of New Tests -- 11. Statistical Concepts in Laboratory Quality Control -- 12. Critical Appraisal of Diagnostic Studies -- 13. Designing Diagnostic Studies -- 14. Statistical Concepts in Modern Pathology Practice.
Format
e-Book
Location
Online
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Evidence-Based Management of Head and Neck Vascular Anomalies

https://libcat.nshealth.ca/en/permalink/provcat42697
edited by Jonathan A. Perkins, Karthik Balakrishnan. --Cham: Springer , c2018.
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This text addresses vascular anomalies and the management of these diverse and clinically challenging set of conditions which have significant impact on patient function, quality of life and, in certain cases, survival. The text covers each category and type of vascular anomaly and the unique diagnostic and therapeutic challenges they pose. The chapters will also include fundamental scientific literature pertaining to each specific condition to help clinicians and clinical researchers better as…
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Other Authors
Perkins, Jonathan A.
Balakrishnan, Karthik
Responsibility
edited by Jonathan A. Perkins, Karthik Balakrishnan
Place of Publication
Cham
Publisher
Springer
Date of Publication
c2018
Physical Description
1 online resource (xvii, 316 p.) : 131 illus., 109 illus. in color
ISBN
9783319923062
9783319923055 (print ed.)
9783319923079 (print ed.)
9783030064020 (print ed.)
Subjects (MeSH)
Head - pathology
Neck - pathology
Vascular Malformations
Specialty
Cardiovascular Surgical Procedures
Pathology
Abstract
This text addresses vascular anomalies and the management of these diverse and clinically challenging set of conditions which have significant impact on patient function, quality of life and, in certain cases, survival. The text covers each category and type of vascular anomaly and the unique diagnostic and therapeutic challenges they pose. The chapters will also include fundamental scientific literature pertaining to each specific condition to help clinicians and clinical researchers better assess and manage vascular anomalies of the head and neck. Each vascular condition will be supported with medical photographs and radiographic images, summaries of diagnostic and therapeutic options, a list of syndromes and genetic mutations known to be associated with each anomaly, case studies, and clinical and research pearls from national and international leaders in the field. Management of Head and Neck Vascular Anomalies: Evidenced-based Assessment will be an invaluable resource for otolaryngologists, plastic surgeons, general and general pediatric surgeons, orthopaedic surgeons, dermatologists, interventional radiologists, residents and fellows in these fields, and researchers with interest in vascular anomalies of the head and neck.
Contents
ISSVA Classification -- Hemangioma -- Cogential (RICH/NICH) -- Infantile Hemangioma -- Location-specific Considerations: Eye, Nasal Tip, and Airway -- Lymphatic Malformation -- Venous Malformation -- Port-wine Stain -- Capillary Malformation -- Arteriovenous Malformations -- Intracranial AVM -- Kaposiform Hemangioendothelioma -- HHT -- Vascular Malignancies -- Site-Specific Considerations: Eye, Nose, Airway.
Format
e-Book
Location
Online
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Dermatopathology A-Z : A Comprehensive Guide

https://libcat.nshealth.ca/en/permalink/provcat42733
Vladimir Vincek. --Cham: Springer , c2018.
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Dermatopathology A-Z is intended to serve as an easily accessible tool for diagnostic criteria and images of all entities that might be encountered. This comprehensive book is designed to help a novice in the field quickly learn diagnostic criteria and memorize the images, while more experienced dermatopathologists or surgical pathologists can quickly refresh their visual memory by reviewing images of two cases of a particular disease. Alphabetically organized, this image-heavy text provides vi…
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Author
Vincek, Vladimir
Responsibility
Vladimir Vincek
Place of Publication
Cham
Publisher
Springer
Date of Publication
c2018
Physical Description
1 online resource (xxiv, 682 p.) : 2334 illus. in color
ISBN
9783319894867
9783319894850 (print ed.)
9783319947327 (print ed.)
Subjects (MeSH)
Skin Diseases - diagnosis
Skin Diseases - pathology
Specialty
Dermatology
Pathology
Abstract
Dermatopathology A-Z is intended to serve as an easily accessible tool for diagnostic criteria and images of all entities that might be encountered. This comprehensive book is designed to help a novice in the field quickly learn diagnostic criteria and memorize the images, while more experienced dermatopathologists or surgical pathologists can quickly refresh their visual memory by reviewing images of two cases of a particular disease. Alphabetically organized, this image-heavy text provides visual aid and succint pathological description on nearly 600 different diseases.
Format
e-Book
Publication Type
Atlas
Location
Online
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Bone Marrow Failure

https://libcat.nshealth.ca/en/permalink/provcat42752
Gary M. Kupfer, Gregory H. Reaman, Franklin O. Smith, editors. --Cham: Springer , c2018.
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This book presents the latest scientific knowledge on inherited and acquired bone marrow failure syndromes, describing the advances in understanding of genetics and pathophysiology that have been achieved as a result of high-throughput DNA sequencing, RNA expression studies, and modern biochemistry techniques. The full range of relevant conditions is covered, including acquired aplastic anemia, Fanconi anemia, ribosomopathies, telomeropathies, dyskeratosis congenita, Shwachman-Diamond syndrome,…
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Other Authors
Kupfer, Gary M.
Reaman, Gregory H.
Smith, Franklin O.
Responsibility
Gary M. Kupfer, Gregory H. Reaman, Franklin O. Smith, editors
Place of Publication
Cham
Publisher
Springer
Date of Publication
c2018
Physical Description
1 online resource (ix, 214 p.) : 19 illus., 12 illus. in color
Series Title
Pediatric oncology
ISBN
9783319614212
9783319614205 (print ed.)
9783319614229 (print ed.)
9783030096625 (print ed.)
ISSN
1613-5318
Subjects (MeSH)
Bone Marrow - physiopathology
Bone Marrow Diseases
Specialty
Hematology
Pathology
Abstract
This book presents the latest scientific knowledge on inherited and acquired bone marrow failure syndromes, describing the advances in understanding of genetics and pathophysiology that have been achieved as a result of high-throughput DNA sequencing, RNA expression studies, and modern biochemistry techniques. The full range of relevant conditions is covered, including acquired aplastic anemia, Fanconi anemia, ribosomopathies, telomeropathies, dyskeratosis congenita, Shwachman-Diamond syndrome, Diamond-Blackfan anemia, and congenital neutropenias and thrombocytopenias. In addition, it is explained how the study of these rare diseases has uncovered important new science and elucidated the pathophysiology of more common hematological and oncological diseases. A treatment-specific chapter describes options ranging from the conventional to the cutting edge. Bone Marrow Failure will be of value for both trainee and practicing hematologists and oncologists.
Contents
1. The Cellular and Molecular Mechanisms of Hematopoiesis -- 2. Acquired Aplastic Anemia -- 3. Pediatric Myelodysplastic Syndromes -- 4. Fanconi Anemia: A Pathway of Hematopoeisis and Cancer Predisposition -- 5. Ribosomopathies Through a Diamond Lens -- 6. Dyskeratosis Congenita and the Telomere Biology Disorders -- 7. Diamond Blackfan Anemia -- 8. Shwachman-Diamond Syndrome -- 9. Hematopoietic Cell Transplantation for the Treatment of Patients with Bone Marrow Failure Syndromes -- 10. Inherited Neutropenias and Their Insights into Cellular and Developmental Biology -- 11. Inherited Thrombocytopenias.
Format
e-Book
Location
Online
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Osteocardiology : Cardiac Bone Formation

https://libcat.nshealth.ca/en/permalink/provcat42770
Nalini M. Rajamannan. --Cham: Springer , c2018.
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This book describes the field of osteocardiology, an exciting and new sub-discipline within cardiovascular science, which will become the cornerstone for defining the timing and treatment of cardiovascular calcification in the future. With the advent of large cohort databases and experimental mechanistic studies, research has elucidated evidence confirming that traditional cardiovascular risk factors are responsible for the development of atherosclerotic calcification and identified the critica…
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Author
Rajamannan, Nalini M.
Responsibility
Nalini M. Rajamannan
Place of Publication
Cham
Publisher
Springer
Date of Publication
c2018
Physical Description
1 online resource (xiv, 99 p.) : 22 illus. in color
ISBN
9783319649948
9783319649931 (print ed.)
9783319649955 (print ed.)
9783319879215 (print ed.)
Subjects (MeSH)
Cardiovascular Diseases - etiology
Osteogenesis
Vascular Calcification - physiopathology
Specialty
Cardiology
Osteology
Pathology
Abstract
This book describes the field of osteocardiology, an exciting and new sub-discipline within cardiovascular science, which will become the cornerstone for defining the timing and treatment of cardiovascular calcification in the future. With the advent of large cohort databases and experimental mechanistic studies, research has elucidated evidence confirming that traditional cardiovascular risk factors are responsible for the development of atherosclerotic calcification and identified the critical elements of atherosclerosis, including foam cell formation, vascular smooth muscle cell proliferation and extracellular matrix synthesis, which over time forms bone in the heart. Osteocardiology: Cardiac Bone Formation is a practical overview of bone formation in the heart and is destined to become the cornerstone for education of medical students, residents, fellows, graduate students, physician scientists and scientists, for future research and ongoing development in medical therapies to slow or halt the progression of bone formation in the heart.
Contents
1. Osteocardiology Risk Factors -- 2. Coronary Artery Calcification -- 3. Osteocardiology: Calcific Aortic Valve Disease -- 4. Osteocardiology: Calcific Aortic Disease -- 5. Osteocardiology: Endochondral Bone Formation -- 6. Osteocardiology: The Atherosclerotic Bone Paradox -- 7. Osteocardiology: Cellular Origins of Cardiac Calcification -- 8. Osteocardiology: LDL-Density-Gene Theory -- 9. Osteocardiology: The LDL-Density-Mechanostat Theory -- 10. Osteocardiology: The Go/No Go Theory For Clinical Trials.
Format
e-Book
Location
Online
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Precision Molecular Pathology of Prostate Cancer

https://libcat.nshealth.ca/en/permalink/provcat42811
Brian D. Robinson, Juan Miguel Mosquera, Jae Y. Ro, Mukul Divatia, editors. --Cham: Springer , c2018.
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This volume focuses on our current understanding of the molecular underpinnings of prostate cancer and their potential application for precision medicine approaches. The emergence and applications of new technologies has allowed for a rapid expansion of our understanding of the molecular basis of prostate cancer and has revealed a remarkable genetic heterogeneity that may underlie the clinically variable behavior of the disease. The book consists of five sections which provide insight about the…
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Other Authors
Robinson, Brian D.
Mosquera, Juan Miguel
Ro, Jae Y.
Divatia, Mukul
Responsibility
Brian D. Robinson, Juan Miguel Mosquera, Jae Y. Ro, Mukul Divatia, editors
Place of Publication
Cham
Publisher
Springer
Date of Publication
c2018
Physical Description
1 online resource (xiv, 570 p.) : 50 illus., 48 illus. in color
Series Title
Molecular pathology library
ISBN
9783319640969
9783319640945 (print ed.)
9783319640952 (print ed.)
9783319877211 (print ed.)
ISSN
1935-987X
Subjects (MeSH)
Precision Medicine
Prostatic Neoplasms - genetics
Prostatic Neoplasms - pathology
Specialty
Medical Oncology
Molecular Medicine
Pathology
Precision Medicine
Urology
Abstract
This volume focuses on our current understanding of the molecular underpinnings of prostate cancer and their potential application for precision medicine approaches. The emergence and applications of new technologies has allowed for a rapid expansion of our understanding of the molecular basis of prostate cancer and has revealed a remarkable genetic heterogeneity that may underlie the clinically variable behavior of the disease. The book consists of five sections which provide insight about the following: (1) General principles; (2) Molecular signatures of primary prostate cancer; (3) Molecular signatures of advanced prostate cancer; (4) Key molecular pathways in prostate cancer development and progression; (5) Precision medicine approach: Diagnosis, treatment, prognosis. Precision Molecular Pathology of Prostate Cancer is an important resource for the practicing oncologist, urologist, and pathologist, and will also be useful for researchers in the prostate cancer community.
Contents
Part I. General Principles -- 1. Precision Medicine in Prostate Cancer: Approach to the Patient -- 2. Epidemiology and Etiology -- 3. High-Grade Prostatic Intraepithelial Neoplasia -- 4. Pathology of Prostate Cancer -- 5. Genetic Susceptibility -- 6. Racial Differences -- 7. Cancer Stem Cells -- Part II. Molecular Signatures of Primary Prostate Cancer -- 8. Prostate Cancer Risk: Single Nucleotide Polymorphisms (SNPs) -- 9. Copy Number Variation/Chromosomal Aberration -- 10. Gene Fusions -- 11. Gene Expression Analysis -- 12. Next-Generation Sequencing -- 13. Epigenetic Alterations in Primary Prostate Cancer -- 14. Proteomics in Prostate Cancer Research -- 15. Metabolomic-Based Stratification in Prostate Cancer -- 16. Tumor Microenvironment: Prospects for Diagnosis and Prognosis of Prostate Cancer Based on Changes in Tumor-Adjacent Stroma -- Part III. Molecular Signatures of Advanced Prostate Cancer -- 17. Metastatic Prostate Cancer -- 18. Castration-Resistant Prostate Cancer -- 19. Neuroendocrine Prostate Cancer -- Part IV. Key Molecular Pathways in Prostate Cancer Development and Progression -- 20. The Role of Androgen Receptor in Prostate Cancer -- 21. PI3K/Akt/mTOR/PTEN and ERK/MAPK Pathways -- 22. The Cell Cycle and Androgen Signaling Interactions in Prostate Cancer -- 23. DNA Damage Repair -- 24. Tyrosine Kinase Receptor Signaling in Prostate Cancer -- 25. Microtubules in Prostate Cancer -- Part V. Precision Medicine Approach: Diagnosis, Treatment, Prognosis -- 26. Prostate Cancer Tissue Diagnosis -- 27. Molecular Imaging of Prostate Cancer: Radiopharmaceuticals for Positron Emission Tomography (PET) and Single-Photon Emission Computed Tomography (SPECT) -- 28. Prostate Cancer Molecular Prognosis -- 29. Molecular Targeted Therapies of Prostate Cancer -- 30. Overview of Prostate Cancer Molecular Classification.
Format
e-Book
Location
Online
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Central Nervous System Intraoperative Cytopathology

https://libcat.nshealth.ca/en/permalink/provcat42816
César R. Lacruz, Javier Saénz de Santamaría, Ricardo H. Bardales. (Second edition) --Cham: Springer , c2018.
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This book covers the full spectrum of benign and malignant conditions of the central nervous system with emphasis cytomorphologic characteristics and differential diagnosis. The volume is heavily illustrated and contains useful algorithms that guide the reader through the differential diagnosis of common and uncommon entities encountered in the field of intraoperative neuro-cytopathology. Central Nervous System Intraoperative Cytopathology serves as a valuable reference for pathologists, cytopa…
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Author
Lacruz, César R.
Other Authors
Saénz de Santamaría, Javier
Bardales, Ricardo H.
Responsibility
César R. Lacruz, Javier Saénz de Santamaría, Ricardo H. Bardales
Edition
Second edition
Place of Publication
Cham
Publisher
Springer
Date of Publication
c2018
Physical Description
1 online resource (xv, 420 p.) : 210 illus., 204 illus. in color
Series
Essentials in cytopathology
Series Vol.
13
Series Title
Essentials in cytopathology series
ISBN
9783319984919
9783319984902 (print ed.)
9783319984926 (print ed.)
ISSN
1574-9053
Subjects (MeSH)
Central Nervous System Diseases - pathology
Central Nervous System Neoplasms - pathology
Cytodiagnosis
Intraoperative Period
Specialty
Cell Biology
Neurology
Pathology
Abstract
This book covers the full spectrum of benign and malignant conditions of the central nervous system with emphasis cytomorphologic characteristics and differential diagnosis. The volume is heavily illustrated and contains useful algorithms that guide the reader through the differential diagnosis of common and uncommon entities encountered in the field of intraoperative neuro-cytopathology. Central Nervous System Intraoperative Cytopathology serves as a valuable reference for pathologists, cytopathologists, and fellows and trainees by providing a concise guide of the current critical information needed to recognize, understand, and interpret this demanding field of surgical neuropathology.
Contents
Introduction to CNS Intraoperative Cytopathology -- Clinical and Radiological Approach to CNS Intraoperative Diagnosis -- Specimen Handling and Optimal Processing -- Algorithmic Approach to CNS Intraoperative Cytopathology -- Normal Brain and Gliosis -- Astrocytic Tumors -- Oligodendroglial Tumors -- Ependymal Tumors -- Other Gliomas -- Choroid Plexus Tumors -- Neuronal and Mixed Neuronal-Glial Tumors -- Embryonal (Primitive) Tumors -- Meningiomas -- Nonmeningotelial Mesenchymal Tumors -- Germ Cell Tumors -- Lymphomas and Histiocytic Tumors -- Nerve Sheath Tumors of the Craniospinal Axis -- Metastatic Tumors -- Benign Cystic Lesions -- Infectious, Inflammatory, and Reactive Lesions -- Pineal Region -- Sellar Region -- Spine and Epidural Space -- Appendix A: Diagnoses that May Change the Surgical Approach -- Appendix B: Troubleshooting with CNS Intraoperative Consultation.
Format
e-Book
Location
Online
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