This book provides guidance to all professionals working with children who present with injuries, neglect, illness falsification and other forms of child abuse. Clinical findings and the current literature are analyzed. The author’s clinical experience is shared to assist the reader in diagnosing the cause of injury and other presentations. This text is the result of many years of experience in the UK working with children in an East London hospital (which receives over 1000 children a week thr…
This book covers topical subjects within the field of death investigation, where changes in practice have recently occurred. As the area of dating of wounds has changed since the subject was addressed in a previous volume, this subject is revisited for the first time. The remaining subjects covered in this volume embrace the multi-disciplinary approach required for death investigation, and address advances in the field of forensic radiology imaging, pathology, and toxicology. There is also a ch…
Using a practical, case-based format, this superbly illustrated atlas by Dr. Paul Sorajja is a comprehensive collection of more than 130 professional experiences in treating structural heart disease. Organized by pathology, each case presents key clinical points for practitioners at all levels, from beginner to expert. Cases are provided by interventionalists and surgeons with extensive hands-on experience, and edited by experts in the field.
This introduces the theoretical and practical guide of NOSES. The book introduced 10 different techniques of NOSES for colorectal neoplasms based on extensive high-quality surgical images. The first part mainly describes the development process of NOSES and the current achievements of these techniques which will provide readers a general understanding of NOSES. The second part elaborates on ten different surgical procedures specific to position of tumor location of NOSES in detail. All key tech…
This book presents current understanding of the importance of modern immunology in the etiopathogenesis of human diseases and explores how this understanding is impacting on diagnosis, prognosis, treatment, and prophylaxis. As the core of modern immunology, the "danger/injury model" is introduced and addressed throughout the book. Volume I of the book describes the network of damage-associated molecular pattern molecules (DAMPs) and examines the central role of DAMPs in cellular stress response…
This text focuses on all aspects of non-gynecologic cytopathology, from key features of benign and malignant lesions, to diagnostic pearls and ancillary testing. Although this book is written by multiple authors, all chapters follow a similar format: brief introduction of the specific organ/system (including types of specimens and techniques to obtain samples), description of normal findings, and a practical approach to diagnose benign and malignant lesions. Key cytomorphological features, curr…
This book covers the complete field of pleura and mediastinum pathology - from acquired multilocular thymic cyst to well-differentiated papillary mesothelioma. The alphabetically arranged entries, each of which provides a detailed description of a specific pathological disease pattern, allow readers to quickly and easily find the information they need.
This book provides a comprehensive, state-of-the art review of pediatric oncology. The text covers relevant concepts in molecular biology and addresses technical principles, applications, challenges, and integration of current and emerging genomic and molecular methods in the diagnosis and personalized management of childhood cancers. The text also discusses a wide array of pediatric neoplasms in the context of molecular pathology in a concise and understandable manner, with focus on their mole…
This book focuses on precursor lesions, borderline lesions, and early carcinomas of female-specific organs from the standpoint of pathology. In 2012, the latest WHO Classification of Tumours of the Breast, 4th ed., was published and subsequently, in 2014, the WHO Classification of Tumours of Female Reproductive Organs, 4th ed., was published. In these fourth editions, several new concepts are addressed that were not described in the previous editions, and many of them are related to the awarene…
This book presents the basic concepts for understanding and practicing breast pathology in routine practice. It explains how to tackle the diagnosis, emphasizing diagnostic clues for each entity as well as pitfalls and mimickers. Each chapter has concise, relevant text illustrated by numerous high-quality pictures highlighting the pearls and challenges in the diagnosis of breast lesions. Experts from around the world describe common and rarer conditions affecting the breast. Histology, immunohi…
This text provides a comprehensive and practical review of the main statistical methods in pathology and laboratory medicine. It introduces statistical concepts used in pathology and laboratory medicine. The information provided is relevant to pathologists both for their day to day clinical practice as well as in their research and scholarly activities. The text will begins by explaining the fundamentals concepts in statistics. In the later sections, these fundamental concepts are expanded and …
This text addresses vascular anomalies and the management of these diverse and clinically challenging set of conditions which have significant impact on patient function, quality of life and, in certain cases, survival. The text covers each category and type of vascular anomaly and the unique diagnostic and therapeutic challenges they pose. The chapters will also include fundamental scientific literature pertaining to each specific condition to help clinicians and clinical researchers better as…
Dermatopathology A-Z is intended to serve as an easily accessible tool for diagnostic criteria and images of all entities that might be encountered. This comprehensive book is designed to help a novice in the field quickly learn diagnostic criteria and memorize the images, while more experienced dermatopathologists or surgical pathologists can quickly refresh their visual memory by reviewing images of two cases of a particular disease. Alphabetically organized, this image-heavy text provides vi…
This book presents the latest scientific knowledge on inherited and acquired bone marrow failure syndromes, describing the advances in understanding of genetics and pathophysiology that have been achieved as a result of high-throughput DNA sequencing, RNA expression studies, and modern biochemistry techniques. The full range of relevant conditions is covered, including acquired aplastic anemia, Fanconi anemia, ribosomopathies, telomeropathies, dyskeratosis congenita, Shwachman-Diamond syndrome,…
This book describes the field of osteocardiology, an exciting and new sub-discipline within cardiovascular science, which will become the cornerstone for defining the timing and treatment of cardiovascular calcification in the future. With the advent of large cohort databases and experimental mechanistic studies, research has elucidated evidence confirming that traditional cardiovascular risk factors are responsible for the development of atherosclerotic calcification and identified the critica…
This volume focuses on our current understanding of the molecular underpinnings of prostate cancer and their potential application for precision medicine approaches. The emergence and applications of new technologies has allowed for a rapid expansion of our understanding of the molecular basis of prostate cancer and has revealed a remarkable genetic heterogeneity that may underlie the clinically variable behavior of the disease. The book consists of five sections which provide insight about the…
This book covers the full spectrum of benign and malignant conditions of the central nervous system with emphasis cytomorphologic characteristics and differential diagnosis. The volume is heavily illustrated and contains useful algorithms that guide the reader through the differential diagnosis of common and uncommon entities encountered in the field of intraoperative neuro-cytopathology. Central Nervous System Intraoperative Cytopathology serves as a valuable reference for pathologists, cytopa…