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Color atlas of pathophysiology

https://libcat.nshealth.ca/en/permalink/provcat42055
Stefan Silbernagl, Florian Lang ; 195 color plates by Rüdiger Gay and Astried Rothenburger ; translator, Geraldine O'Sullivan. (3rd edition) --Stuttgart: Thieme , c2016.
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Author
Silbernagl, Stefan
Other Authors
Lang, Florian, 1945-
Responsibility
Stefan Silbernagl, Florian Lang ; 195 color plates by Rüdiger Gay and Astried Rothenburger ; translator, Geraldine O'Sullivan
Edition
3rd edition
Alternate Title
Colour atlas of pathophysiology
Pathophysiology
Place of Publication
Stuttgart
Publisher
Thieme
Date of Publication
c2016
Physical Description
1 online resource (x, 438 pages) : illustrations
ISBN
9783131165534
9783131490636 (eISBN)
Subjects (MeSH)
Pathology
Physiological Phenomena
Specialty
Pathology
Physiology
Contents
Fundamentals -- Temperature, energy -- Blood -- Kidney, salt and water balance -- Stomach, intestines, liver -- Heart and circulation -- Metabolic disorders -- Hormones -- Neuromuscular and sensory systems.
Format
e-Book
Publication Type
Atlas
Location
Online
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Medical physiology Q&A

https://libcat.nshealth.ca/en/permalink/provcat42076
Waite, Gabi Nindl. --New York, NY: Thieme , c2018.
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Location
Online
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Author
Waite, Gabi Nindl
Other Authors
Sheakley, Maria
Alternate Title
Thieme test prep for the USMLE® - Medical physiology Q&A
Medical physiology questions & answers
Medical physiology questions and answers
Place of Publication
New York, NY
Publisher
Thieme
Date of Publication
c2018
Physical Description
1 online resource
Series
Thieme test prep for the USMLE
ISBN
9781626233843
9781626233850 (eISBN)
Subjects (MeSH)
Physiological Phenomena
Specialty
Physiology
Contents
Cellular physiology -- The nervous system -- Musculoskeletal and integumentary systems -- Blood and immune systems -- Cardiovascular and lymphatic systems -- Respiratory system -- Renal and urinary systems -- Gastrointestinal system -- Endocrine system -- Reproductive system -- Multisystem processes and disorders.
Format
e-Book
Publication Type
Examination Questions
Location
Online
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Physiology : an illustrated review

https://libcat.nshealth.ca/en/permalink/provcat42081
Roger TannerThies. --New York, NY: Thieme , c2012.
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"Physiology--An Illustrated Review helps you master important physiologic facts and concepts and teaches you how to apply that knowledge successfully on course exams and in daily practice. This indispensable review book includes 200 spectacular, full-color illustrations depicting cardiologic, cellular, and renal function. It also includes all the regular series features, including 400 print and online review questions and explanatory answers"--Provided by publisher.
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Author
TannerThies, Roger
Responsibility
Roger TannerThies
Place of Publication
New York, NY
Publisher
Thieme
Date of Publication
c2012
Physical Description
1 online resource (x, 329 p.) : ill.
Series
Illustrated review series
Series Title
Thieme's illustrated review series
ISBN
9781604062021
9781604062038 (eISBN)
Subjects (MeSH)
Physiological Phenomena
Specialty
Physiology
Abstract
"Physiology--An Illustrated Review helps you master important physiologic facts and concepts and teaches you how to apply that knowledge successfully on course exams and in daily practice. This indispensable review book includes 200 spectacular, full-color illustrations depicting cardiologic, cellular, and renal function. It also includes all the regular series features, including 400 print and online review questions and explanatory answers"--Provided by publisher.
Format
e-Book
Publication Type
Atlas
Examination Questions
Outline
Location
Online
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Neuromodulation : comprehensive textbook of principles, technologies, and therapies

https://libcat.nshealth.ca/en/permalink/provcat42093
edited by Elliot S. Krames, P. Hunter Peckham, Ali R. Rezai. (2nd ed.) --London, UK: Elsevier , c2018.
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Neuromodulation: Comprehensive Textbook of Principles, Technologies, and Therapies, Second Edition, serves as a comprehensive and in-depth reference textbook covering all aspects of the rapidly growing field of neuromodulation. Since the publication of the first edition seven years ago, there has been an explosion of knowledge in neuromodulation, optogenetics, bioelectronics medicine and brain computer interfacing. Users will find unique discussions of the fundamental principles of neuromodul…
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Other Authors
Krames, Elliot S.
Responsibility
edited by Elliot S. Krames, P. Hunter Peckham, Ali R. Rezai
Edition
2nd ed.
Alternate Title
Comprehensive textbook of principles, technologies, & therapies
Place of Publication
London, UK
Publisher
Elsevier
Date of Publication
c2018
Physical Description
1 online resource, 1828 p.
ISBN
9780128053539
Subjects (MeSH)
Deep Brain Stimulation
Brain - physiology
Neurosurgical Procedures
Neuroimaging
Subjects (LCSH)
Neural transmission - Regulation
Neurotransmitters
Neural stimulation
Deep Brain Stimulation - methods
Electric Stimulation Therapy - methods
Implantable Neurostimulators
Nervous System Diseases - therapy
Neurosurgical Procedures - methods
Neural conduction
Neurochemistry
Neurons
Neurophysiology
Specialty
Neurology
Physiology
Abstract
Neuromodulation: Comprehensive Textbook of Principles, Technologies, and Therapies, Second Edition, serves as a comprehensive and in-depth reference textbook covering all aspects of the rapidly growing field of neuromodulation. Since the publication of the first edition seven years ago, there has been an explosion of knowledge in neuromodulation, optogenetics, bioelectronics medicine and brain computer interfacing. Users will find unique discussions of the fundamental principles of neuromodulation and therapies, and how they are applied to the brain, spinal cord, peripheral nerves, autonomic nerves and various organs.
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Format
e-Book
Location
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Physiology of the gastrointestinal tract

https://libcat.nshealth.ca/en/permalink/provcat42115
editor in chief Hamid Said. (3rd ed.) --London, UK: Elsevier , c2018.
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Physiology of the Gastrointestinal Tract, Sixth Edition, a Two-Volume set, covers the study of the mechanical, physical and biochemical functions of the GI Tract by linking clinical disease and disorder, thus bridging the gap between clinical and laboratory medicine while also covering breakthroughs in gastroenterology, such as the brain-gut axis and microbiome. Additionally, information is provided at the organism level, including animal models of gastrointestinal disorders and therapeutic po…
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Other Authors
Said, Hamid
Responsibility
editor in chief Hamid Said
Edition
3rd ed.
Place of Publication
London, UK
Publisher
Elsevier
Date of Publication
c2018
Physical Description
1 online resource, 1812 p.
ISBN
9780128099544
Subjects (MeSH)
Gastrointestinal Tract - physiology
Subjects (LCSH)
Gastrointestinal system
Specialty
Gastroenterology
Physiology
Abstract
Physiology of the Gastrointestinal Tract, Sixth Edition, a Two-Volume set, covers the study of the mechanical, physical and biochemical functions of the GI Tract by linking clinical disease and disorder, thus bridging the gap between clinical and laboratory medicine while also covering breakthroughs in gastroenterology, such as the brain-gut axis and microbiome. Additionally, information is provided at the organism level, including animal models of gastrointestinal disorders and therapeutic possibilities. The book covers a wide range of conditions, from food allergies, constipation, chronic liver disease and IBS, also exploring emerging techniques to diagnose and normalize functions of the GI tract.
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Format
e-Book
Location
Online
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Epilepsy and behavior case reports

https://libcat.nshealth.ca/en/permalink/provcat42119
Elsevier
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Holdings
Vol 1, 2013 - Vol 11, 2019
Location
Online
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Alternate Title
Epilepsy and behaviour case reports
Publisher
Elsevier
Holdings
Vol 1, 2013 - Vol 11, 2019
Publication Frequency
Annual
ISSN
2213-3232
Specialty
Physiology
Format
e-Journal
Location
Online
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Olaf Rusoke-Dierich. --Cham: Springer , c2018.
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Online
This book is the very first to cover the decompression theory in detail. It gives many information on all topics of the diving medicine, and is richly and uniquely illustrated. It offers a good guideline of high quality practice in diving medicine. The author provides a very structured and easy to understand book, by covering all aspects of the diving medicine, such as equipment, physiology, and related issues as gas intoxications, venomous animals or damages that can occur in the diving practi…
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Author
Rusoke-Dierich, Olaf
Responsibility
Olaf Rusoke-Dierich
Place of Publication
Cham
Publisher
Springer
Date of Publication
c2018
Physical Description
1 online resource (xv, 440 p.) : 237 illus., 233 illus. in color
ISBN
9783319738369
9783319738352 (print ed.)
9783319738376 (print ed.)
Subjects (MeSH)
Barotrauma
Decompression Sickness
Diving - physiology
Specialty
Physiology
Sports Medicine
Abstract
This book is the very first to cover the decompression theory in detail. It gives many information on all topics of the diving medicine, and is richly and uniquely illustrated. It offers a good guideline of high quality practice in diving medicine. The author provides a very structured and easy to understand book, by covering all aspects of the diving medicine, such as equipment, physiology, and related issues as gas intoxications, venomous animals or damages that can occur in the diving practice. Relevant physiological and anatomical illustrations enlight even complex topics. The Diving medicine book will appeal to health experts like doctors and nurses, but also to diving schools and teachers.
Contents
[Part] I. Introduction -- 1. Diving History -- 2. Basic Diving Equipment -- 3. Scuba Diving -- 4. Dive Tables and Dive Computers -- 5. Tech Diving -- [Part] II. Diving Physics -- 6. Composition of the Normal Air -- 7. Pressure -- 8. Physical Behaviour of Gas -- 9. Decompression Theory -- 10. Bubble Flow -- 11. Archimedes’ Principle -- 12. Optical and Acoustic Changes Underwater -- 13. Thermal Conductivity -- 14. Conversion Tables for Physical Units -- [Part] III. Diving Physiology and Anatomy -- 15. Diving Physiology and Anatomy -- 16. Respiration -- 17. Nervous System -- 18. Sensory Organs -- 19. Energy Balance -- 20. Nutrition -- 21. Temperature Regulation -- 22 .Acid-Base Balance -- [Part] IV. Diving Medicine -- 23. Barotrauma -- 24. Decompression Illness (DCI) -- 25. Oxygen Window -- 26. Intoxication of Breathing Gases During Diving -- 27. Apnoea Diving -- 28. Damage Caused by External Factors -- 29. Venomous and Dangerous Marine Animals -- 30. Assessment for Diving Fitness for Recreational Divers -- 31. First Aid -- 32. Travel Medicine.
Format
e-Book
Location
Online
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Energy Balance and Prostate Cancer

https://libcat.nshealth.ca/en/permalink/provcat43025
Elizabeth A. Platz, Nathan A. Berger, editors. --Cham: Springer , c2018.
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This volume provides a comprehensive treatise on the latest studies linking prostate cancer with energy balance, which together constitute a major challenge and opportunity for research scientists and clinicians especially those dealing with the expanding population of older men confronted with obesity and associated comorbidities. This volume should be a valuable resource to physicians, oncologists, urologists, endocrinologists, nurses, nutritionists, dieticians, and exercise therapists dealin…
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Other Authors
Platz, Elizabeth A.
Berger, Nathan A.
Responsibility
Elizabeth A. Platz, Nathan A. Berger, editors
Place of Publication
Cham
Publisher
Springer
Date of Publication
c2018
Physical Description
1 online resource (xii, 187 p.) : 11 illus., 10 illus. in color
Series Vol.
v. 14
Series Title
Energy balance and cancer
ISBN
9783319649405
9783319649399 (print ed.)
9783319649412 (print ed.)
9783319879062 (print ed.)
ISSN
2199-2622
Subjects (MeSH)
Energy Metabolism
Obesity - complications
Prostatic Neoplasms - etiology
Prostatic Neoplasms - metabolism
Risk Factors
Specialty
Medical Oncology
Physiology
Urology
Abstract
This volume provides a comprehensive treatise on the latest studies linking prostate cancer with energy balance, which together constitute a major challenge and opportunity for research scientists and clinicians especially those dealing with the expanding population of older men confronted with obesity and associated comorbidities. This volume should be a valuable resource to physicians, oncologists, urologists, endocrinologists, nurses, nutritionists, dieticians, and exercise therapists dealing with men with energy balance issues and/or questions regarding the linkage between energy balance and cancer. Moreover, this volume should serve as an important resource for cancer researchers especially for scientists studying lifestyle modification and prevention strategies to better understand and disrupt the linkage between obesity and cancer.
Contents
1. Epidemiology, Energy Balance and Prostate Cancer Incidence and Mortality -- 2. Racial/Ethnic Differences in the Association between Energy Balance and Prostate Cancer -- 3. Consequence of Energy Imbalance in Prostate Cancer and Comorbidities -- 4. Adipokines and Prostate Cancer -- 5. Cross-Sectional Epidemiology and Intervention Studies of Mediators of the Energy Imbalance-Prostate Cancer Association -- 6. Impact of Metabolic Factors on Screening, Early Detection, and Management of Prostate Cancer -- 7. Androgen Deprivation Therapy for Prostate Cancer: Effects on Body Composition and Metabolic Health -- 8. The Integration of Exercise and Dietary Lifestyle Interventions into Prostate Cancer Care -- 9. Energy Balance-Based Strategies to Reduce Consequences of Prostate Cancer: How to Communicate with Men.
Format
e-Book
Location
Online
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Coronary Imaging and Physiology

https://libcat.nshealth.ca/en/permalink/provcat43026
Myeong-Ki Hong, editor. --Singapore: Springer , c2018.
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This book is intended as a guide for all cardiologists who are interested in coronary imaging and physiology, a sound understanding of which is vital for the optimal performance of appropriate coronary interventions. The basics of each relevant modality are presented, with clear explanation of clinical utility and evaluation of the evidence regarding clinical outcomes. All technical methods are described in detail, and the text is complemented by numerous helpful tables and illustrations. The e…
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Other Authors
Hong, Myeong-Ki
Responsibility
Myeong-Ki Hong, editor
Place of Publication
Singapore
Publisher
Springer
Date of Publication
c2018
Physical Description
1 online resource (xvii, 331 p.) : 200 illus., 154 illus. in color
ISBN
9789811027871
9789811027864 (print ed.)
9789811027888 (print ed.)
9789811097041 (print ed.)
Subjects (MeSH)
Coronary Disease - diagnostic imaging
Coronary Vessels - physiology
Specialty
Cardiology
Diagnostic Imaging
Physiology
Abstract
This book is intended as a guide for all cardiologists who are interested in coronary imaging and physiology, a sound understanding of which is vital for the optimal performance of appropriate coronary interventions. The basics of each relevant modality are presented, with clear explanation of clinical utility and evaluation of the evidence regarding clinical outcomes. All technical methods are described in detail, and the text is complemented by numerous helpful tables and illustrations. The effectiveness of intravascular coronary imaging in improving clinical outcomes is proven, and it is widely used for this purpose. Two modalities for intravascular coronary imaging are available in clinical practice: intravascular ultrasound (IVUS) and optical coherence tomography (OCT). For coronary physiology, the pressure wire-derived fractional flow reserve (FFR) provides information on the functional status of coronary trees. This technique and its clinical applications receive particular attention in the book, which also looks beyond FFR to FFR-CT, a method using computational fluid dynamics, and to invasive assessment of the microcirculation.
Contents
Part I. IVUS -- 1. Physical Principles and Equipment: IVUS -- 2. IVUS Artifacts and Image Control -- 3. Quantitative Measurements of Native Lesion -- 4. Qualitative Assessment of Native Lesion -- 5. Clinical Evidence of Intravascular Ultrasound-Guided Percutaneous Coronary Intervention -- 6 Pre-Percutaneous Coronary Intervention Lesion Assessment -- 7. IVUS: Post-Evaluation After Stenting -- 8. Long-Term Complications and Bioresorbable Vascular Scaffolds Evaluation -- 9. Near-Infrared Spectroscopy -- Part II. OCT -- 10. Physical Principles and Equipment of Intravascular Optical Coherence Tomography -- 11. Image Acquisition Techniques -- 12. Interpretation of Optical Coherence Tomography: Quantitative Measurement -- 13. Qualitative Assessments of Optical Coherence Tomography -- 14. Clinical Evidence of Optical Coherence Tomography-Guided Percutaneous Coronary Intervention -- 15. Pre-interventional Lesion Assessment -- 16. Immediate Post-Stent Evaluation with Optical Coherence Tomography -- 17. Late Stent Evaluation (Neoatherosclerosis) -- 18. Bioresorbable Vascular Scaffold Evaluation by Optical Coherence Tomography - 19. Novel Application of OCT in Clinical Practice -- Part III. Physiology -- 20. Concept of Invasive Coronary Physiology: Focus on FFR -- 21. Setup for Fractional Flow Reserve and Hyperemia -- 22. Validation of Fractional Flow Reserve -- 23. Practical Learning in Coronary Pressure Measurement -- 24. Other Physiologic Indices for Epicardial Stenosis -- 25. Comparison Between Anatomic and Physiologic Indices -- 26. Fractional Flow Reserve in Intermediate or Ambiguous Lesion -- 27. FFR in Complex Lesions -- 28. FFR in Acute Coronary Syndrome and Noncoronary Disease -- 29. Fractional Flow Reserve in Specific Lesion Subsets -- 30. Invasive Assessment for Microcirculation -- 31. Non-invasive Assessment of Myocardial Ischemia.
Format
e-Book
Location
Online
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Disorders of Blood Pressure Regulation : Phenotypes, Mechanisms, Therapeutic Options

https://libcat.nshealth.ca/en/permalink/provcat43028
Adel E. Berbari, Giuseppe Mancia, editors. --Cham: Springer , c2018.
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This book aims to present a comprehensive classification of hypertensive phenotypes based on underlying target organ involvement. Particular emphasis is placed on review and assessment of clinical presentation, pathophysiologic mechanisms, and possible specific therapeutic options for each hypertension phenotype. Several of these phenotypes are well known and well described in the literature, such as prehypertension, white coat and masked hypertension, isolated systolic hypertension, renovascul…
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Other Authors
Berbari, Adel E.
Mancia, Giuseppe
Responsibility
Adel E. Berbari, Giuseppe Mancia, editors
Place of Publication
Cham
Publisher
Springer
Date of Publication
c2018
Physical Description
1 online resource (xi, 880 p.) : 131 illus., 53 illus. in color
Series Title
Updates in Hypertension and Cardiovascular Protection
ISBN
9783319599182
9783319599175 (print ed.)
9783319599199 (print ed.)
9783319867342 (print ed.)
ISSN
2366-4606
Subjects (MeSH)
Hypertension - etiology
Phenotype
Specialty
Cardiology
Physiology
Abstract
This book aims to present a comprehensive classification of hypertensive phenotypes based on underlying target organ involvement. Particular emphasis is placed on review and assessment of clinical presentation, pathophysiologic mechanisms, and possible specific therapeutic options for each hypertension phenotype. Several of these phenotypes are well known and well described in the literature, such as prehypertension, white coat and masked hypertension, isolated systolic hypertension, renovascular hypertension, endocrine hypertension, pediatric hypertension, and gestational hypertension. Other hypertension phenotypes, however, are not widely recognized, being reported only in special reviews; examples include hypertension associated with renal calculus disease and other rarer causes such as Turner syndrome, herbal and medicinal compounds, and pharmacologic agents. A detailed account of the various causes of monogenic hypertension is also included. Finally, a section is devoted to general aspects of hypertension, including the significance of blood pressure indices, the natural course of untreated and treated hypertension, hypertension mechanisms, genetics, and guidelines for blood pressure control.
Contents
Part I: General Aspects -- 1. Introduction: Definition and Classification of Arterial Pressure Phenotypes -- 2. Diagnostic and Prognostic Significance of Blood Pressure Indices -- 3. Role of Circadian Rhythms and Seasonal Variation in BP Levels -- 4. Natural History of Treated and Untreated Hypertension -- Part II: Mechanisms of Hypertension Development -- 5. The Kidneys, Volume and Blood Pressure Regulation, and Hypertension -- 6. Nervous System -- 7. Hormonal Systems -- 8. Vasoactive Peptides -- 9. Endothelial Function -- 10. Genetics of Blood Pressure and Hypertension -- Part III: Hypertension Phenotypes: Monogenic Syndromes -- 11. Monogenic Forms of Hypertension -- 12. Arterial Hypertension in Turner Syndrome -- Part IV: Hypertension Phenotypes: The Heart -- 13. Hypertensive Heart Disease -- 14. Perioperative Cardiac Surgery Hypertension -- 15. Hypertension: Supravalvular Aortic Stenosis -- 16. Coarctation of the Aorta -- 17. Atrial Fibrillation and Hypertension: Two Entities That Usually Coexist -- Part V: Hypertension Phenotypes: The Central Nervous System and the Brain -- 18. Sleep Disturbances/Sleep Apnea -- 19. Stress and Hypertension -- 20. Central Nervous System Disorders: Transient Ischemic Attack and Stroke (Ischemic/Hemorrhagic) -- Part VI: Hypertension Phenotypes: The Kidney -- 21. Chronic Kidney Disease -- 22. Calculus Renal Disease -- 23. Uric Acid-Hypertension Relationships -- 24. Hypertension in Dialysis Patients: Clinical Edidemiology, Pathogenesis, Diagnosis, and Treatment -- 25. Renovascular Hypertension -- 26. Molecular Pathways in Hypertensive Renal Damage -- 27. Determinants of Hypertensive Renal Disease and Its Progression -- Part VII: Hypertension Phenotypes: Endocrine Causes -- 28. Cushing's Syndrome and Glucocorticoid Excess -- 29. Primary Aldosteronism and Its Various Scenarios -- 30. Severe Paroxysmal Hypertension (Pseudopheochromocytoma) -- 31. Paroxysmal Hypertension: Pheochromocytoma -- 32. Hypertension in Thyroid Disorders -- 33. Primary Hyperparathyroidism -- Part VIII: Special Types of Hypertension -- 34. Phenotypic Changes in the Transition from Prehypertension to Established Hypertension -- 35. White Coat and Masked Hypertension -- 36. Isolated Systolic Hypertension: In the Young and in the Elderly -- 37. Treatment of Resistant Hypertension -- 38. Accelerated / Malignant Hypertension -- 39. Nocturnal Hypertension -- 40. Salt and Hypertension -- 41. Diabetes Mellitus and Hypertension -- 42. Obesity and Metabolic Syndrome Hypertension -- 43. Secondary Hypertension: Infrequently Considered Aspects: Illicit/Recreational Substances, Herbal Remedies, and Drug-Associated Hypertension -- Part IX: Hypertensive Phenotypes: Blood Pressure Disorders of Pregnancy and Pediatric Hypertension -- 44. Hypertensive Disorders of Pregnancy -- 45. Blood Pressure Trends in Children and Adolescents: Predictors of Blood Pressure Elevation in Children and Adolescents -- 46. Hypertension in Children and Adolescents -- Part X: Management and Therapeutic Approaches -- 47. What Is New and What Is Different in Recent Guidelines on Antihypertensive Treatment? Looking Forward to Guidelines Reappraisal -- 48. Place of Invasive Procedures in Blood Pressure Control -- 49. Is Hypertension-Related Target Organ Involvement/Damage Reversible/Preventable?
Format
e-Book
Location
Online
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Metabolic Disorders and Critically Ill Patients : From Pathophysiology to Treatment

https://libcat.nshealth.ca/en/permalink/provcat43176
Carole Ichai, Hervé Quintard, Jean-Christophe Orban, editors. --Cham: Springer , c2018.
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The purpose of this book is to bring together the latest findings on metabolic disorders that are strongly implicated in various critically ill patients. Since the beginning of the 20th century, maintaining the "milieu interieur" has been a major challenge for intensivists. In addition to considerable technological developments in intensive care units, important advances in our understanding of metabolic disorders observed in critically ill patients have been made during the 10 last years. Toda…
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Other Authors
Ichai, Carole
Quintard, Hervé
Orban, Jean-Christophe
Responsibility
Carole Ichai, Hervé Quintard, Jean-Christophe Orban, editors
Place of Publication
Cham
Publisher
Springer
Date of Publication
c2018
Physical Description
1 online resource (vi, 477 p.) : 76 illus., 41 illus. in color
ISBN
9783319640105
9783319640082 (print ed.)
9783319640099 (print ed.)
9783319876986 (print ed.)
Subjects (MeSH)
Critical Illness
Metabolic Diseases - physiopathology
Metabolic Diseases - therapy
Specialty
Critical Care
Physiology
Abstract
The purpose of this book is to bring together the latest findings on metabolic disorders that are strongly implicated in various critically ill patients. Since the beginning of the 20th century, maintaining the "milieu interieur" has been a major challenge for intensivists. In addition to considerable technological developments in intensive care units, important advances in our understanding of metabolic disorders observed in critically ill patients have been made during the 10 last years. Today, the intensivist can't ignore these disorders when selecting the most appropriate treatment for an illness. Cellular metabolic abnormalities are responsible for systems and organ failures, so the modern approach of organ dysfunctions now includes prevention or treatment of such disorders. This book is a comprehensive tool, allowing the physician to understand, diagnose and treat these metabolic disorders. Water, electrolyte, acid-base, glycemic and endocrinologic problems, as well as metabolic abnormalities observed in renal, cerebral and hepatic failure are presented in different chapters. The last part of the book is devoted to modern nutritional concepts, the consequences of energy modifications, mitochondrial dysfunction, hypothermia, oxidative stress and ischemia reperfusion, which open the way for new therapies.
Contents
Part I. Fluid and electrolytes disorders -- 1. Water and sodium balances -- 2. Sodium disorders -- 3. Potassium disorders -- 4. Phosphate and calcium disorders -- Part II. Acid-base disorders -- 5. Interpretation of acid-base disorders -- 6. Acidosis : diagnosis and treatment -- 7. Alkalosis : diagnosis and treatment -- 8. Lactate : metabolism, physiopathology -- Part III. Kidney and metabolic disorders -- 9. Metabolism et renal functions -- 10. Extra-renal removal therapies in acute kidney injury -- 11. Strategies for preventing acute kidney failure -- Part IV. Brain and metabolic disorders -- 12. Cerebral metabolism and function -- 13. Cerebral ischemia: patholophysiology, diagnosis and treatment -- 14. Evaluation of cerebral blood flow in the intensive care unit -- Part V. Endocrine disorders in intensive care unit -- 15. Acute complications of diabetes -- 16. Neuroendocrine dysfunction in the critically ill patients -- 17. Hyperglycemia in intensive care unit -- Part VI. Energetic metabolism, Nutrition -- 18. Nutritional requirements in intensive care unit -- 19. Pharmaconutrition in the critically ill patient -- 20. Oxygen, oxidative stress -- 21. Energetic metabolism : from the organ to the cell -- 22. Ischemia-reperfusion concepts of myocardial preconditionning and postconditioning -- 23. Targeted temperature management in severe brain injured patient.
Format
e-Book
Location
Online
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Regulation of Signal Transduction in Human Cell Research

https://libcat.nshealth.ca/en/permalink/provcat43178
Nariyoshi Shinomiya, Hiroaki Kataoka, Qian Xie, editors. --Singapore: Springer , c2018.
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This volume focuses on the relationship between the regulation of signal transduction and disease mechanisms, and discusses how the dysregulation of intracellular signals cause diseases, cell death, carcinogenesis, and other disorders. Growth, survival, transformation, and metabolic activities at the cellular level are regulated by various intracellular signal transduction pathways. Sources that stimulate intracellular signals include intracellular stresses and signal regulators/modulators, as …
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Other Authors
Shinomiya, Nariyoshi
Kataoka, Hiroaki
Xie, Qian
Responsibility
Nariyoshi Shinomiya, Hiroaki Kataoka, Qian Xie, editors
Place of Publication
Singapore
Publisher
Springer
Date of Publication
c2018
Physical Description
1 online resource (viii, 218 p.) : 49 illus., 41 illus. in color
Series Title
Current human cell research and applications
ISBN
9789811072963
9789811072956 (print ed.)
9789811072970 (print ed.)
ISSN
2522-073X
Subjects (MeSH)
Cell Communication - physiology
Signal Transduction - physiology
Specialty
Cell Biology
Physiology
Abstract
This volume focuses on the relationship between the regulation of signal transduction and disease mechanisms, and discusses how the dysregulation of intracellular signals cause diseases, cell death, carcinogenesis, and other disorders. Growth, survival, transformation, and metabolic activities at the cellular level are regulated by various intracellular signal transduction pathways. Sources that stimulate intracellular signals include intracellular stresses and signal regulators/modulators, as well as extracellular growth factors. Recent studies on signal transduction analysis using animal and human cell lines have revealed how the intracellular signals are regulated and why their dysregulation leads to pathological states such as tumorigenesis, metabolic diseases, cell death, and so on. This book highlights several important key molecules and intracellular signaling pathways such as microRNA, the TGF-beta signaling pathway, the Wnt signaling pathway and MET signaling pathway as topical and highly relevant issues in human cell research related to signal transduction. In addition to assessing the pathogenic role of these signaling pathways, it focuses on the molecular design of small molecule regulators/inhibitors of said pathways, one of the most important approaches in this area. This book offers a valuable guide, helping not only research scientists but also clinicians to understand how the dysregulation of intracellular signals leads to diseases.
Contents
1. Using Genetically Engineered Mouse Models to Study Wnt Signaling in Bone Development and Disease -- 2. Role of the Receptor-Mediated Signaling Pathways on the Proliferation and Differentiation of Pluripotent Stem Cells -- 3. Regulation of microRNA Expression by Growth Factors in Tumor Development and Progression -- 4. Regulation of EMT by TGF-ß Signaling in Cancer Cells -- 5. The Functional Interplay Between Pro-oncogenic RUNX2 and Hypoxia-Inducible Factor-1a (HIF-1a) During Hypoxia-Mediated Tumor Progression -- 6. DNA Damage: Cellular Responses, Repair, and Cancer Treatment -- 7. Met Activation and Carcinogenesis -- 8. The HGF/MET Signaling and Therapeutics in Cancer -- 9. Pericellular Activation of Peptide Growth Factors by Serine Proteases -- 10. Molecular Designing of Small-Molecule Inhibitors for Apoptosis Regulation.
Format
e-Book
Location
Online
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Fluid, Electrolyte and Acid-Base Disorders : Clinical Evaluation and Management

https://libcat.nshealth.ca/en/permalink/provcat43204
Alluru S. Reddi. (Second edition) --Cham: Springer , c2018.
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Online
Expanded with six additional chapters and new study questions, this updated edition provides a clear and concise understanding of the fundamentals of fluid, electrolyte and acid-base disorders that are frequently encountered in clinical practice. Each chapter follows a standard format that begins with pertinent basic physiology followed by its clinical disorder. Cases for each fluid, electrolyte and acid-base disorder are discussed, along with board-type questions with explanations to increase …
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Author
Reddi, Alluru S.
Responsibility
Alluru S. Reddi
Edition
Second edition
Place of Publication
Cham
Publisher
Springer
Date of Publication
c2018
Physical Description
1 online resource (xxi, 506 p.) : 56 illus., 53 illus. in color
ISBN
9783319601670
9783319601663 (print ed.)
9783319601687 (print ed.)
Subjects (MeSH)
Acid-Base Imbalance
Body Fluids - metabolism
Water-Electrolyte Imbalance
Specialty
Physiology
Abstract
Expanded with six additional chapters and new study questions, this updated edition provides a clear and concise understanding of the fundamentals of fluid, electrolyte and acid-base disorders that are frequently encountered in clinical practice. Each chapter follows a standard format that begins with pertinent basic physiology followed by its clinical disorder. Cases for each fluid, electrolyte and acid-base disorder are discussed, along with board-type questions with explanations to increase the knowledge for the clinician. Practical and clinically oriented, this book is a handy reference for practicing physicians, students, residents and fellows.
Contents
Part I. Physiologic Basis and Management of Fluid, Electrolyte and Acid-Base Disorders -- 1. Body Fluid Compartments -- 2. Interpretation of Urine Electrolytes and Osmolality -- 3. Renal Handling of NaCl and Water -- 4. Intravenous Fluids: Composition and Indications -- 5. Diuretics -- 6. Disorders of Extracellular Fluid Volume: Basic Concepts -- 7. Disorders of ECF Volume: Congestive Heart Failure -- 8. Disorders of ECF Volume: Cirrhosis of the Liver -- 9. Disorders of ECF Volume: Nephrotic Syndrome -- 10. Disorders of ECF Volume: Volume Contraction -- 11. Disorders of Water Balance: Physiology -- 12. Disorders of Water Balance: Hyponatremia -- 13. Disorders of Water Balance: Hypernatremia -- 14. Disorders of Potassium: Physiology -- 15. Disorders of Potassium: Hypokalemia -- 16. Disorders of Potassium: Hyperkalemia -- 17. Disorders of Calcium: Physiology -- 18. Disorders of Calcium: Hypocalcemia -- 19. Disorders of Calcium: Hypercalcemia -- 20. Disorders of Phosphate: Physiology -- 21. Disorders of Phosphate: Hypophosphatemia -- 22. Disorders of Phosphate: Hyperphosphatemia -- 23. Disorders of Magnesium: Physiology -- 24. Disorders of Magnesium: Hypomagnesemia -- 25. Disorders of Magnesium: Hypermagnesemia -- 26. Acid–Base Physiology -- 27. Evaluation of an Acid–Base Disorder -- 28. High Anion Gap Metabolic Acidosis -- 29. Hyperchloremic Metabolic Acidosis: Renal Tubular Acidosis -- 30. Hyperchloremic Metabolic Acidosis: Nonrenal Causes -- 31. Metabolic Alkalosis -- 32. Respiratory Acidosis -- 33. Respiratory Alkalosis -- 34. Mixed Acid–Base Disorders -- 35. Drug-Induced Acid–Base Disorders -- Part II. Fluid, Electrolyte and Acid-Base Disorders in Special Conditions -- 36. Acute Kidney Injury -- 37. Chronic Kidney Disease -- 38. Kidney Transplantation -- 39. Liver Disease -- 40. Pregnancy.
Format
e-Book
Location
Online
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The Pulvinar Thalamic Nucleus of Non-Human Primates : Architectonic and Functional Subdivisions

https://libcat.nshealth.ca/en/permalink/provcat43209
Ricardo Gattass, Juliana G.M. Soares, Bruss Lima. --Cham: Springer , c2018.
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This book discusses the hypothesis that the primate pulvinar contains an original scaffold which is derived from cytoarchitectural markers and specific protein distributions. Thereafter, along primate evolution, different selective pressures acted in order to shape and fine-tune the connectivity of the pulvinar with specific regions of the neocortex. This divergence created, among other things, the different sets of retinotopic map representations in the pulvinar nucleus depending on functional…
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Author
Gattass, Ricardo
Other Authors
Soares, Juliana G.M.
Lima, Bruss
Responsibility
Ricardo Gattass, Juliana G.M. Soares, Bruss Lima
Place of Publication
Cham
Publisher
Springer
Date of Publication
c2018
Physical Description
1 online resource (vii, 66 p.) : 29 illus., 9 illus. in color
Series Vol.
225
Series Title
Advances in anatomy, embryology and cell biology
ISBN
9783319700465
9783319700458 (print ed.)
9783319700472 (print ed.)
ISSN
0301-5556
Subjects (MeSH)
Biological Evolution
Primates
Pulvinar
Specialty
Neurology
Physiology
Zoology
Abstract
This book discusses the hypothesis that the primate pulvinar contains an original scaffold which is derived from cytoarchitectural markers and specific protein distributions. Thereafter, along primate evolution, different selective pressures acted in order to shape and fine-tune the connectivity of the pulvinar with specific regions of the neocortex. This divergence created, among other things, the different sets of retinotopic map representations in the pulvinar nucleus depending on functional and behavioral requirements of each species. The pulvinar, the largest nucleus of the primate thalamus, has extensive and reciprocal connections with several areas of the neocortex. These input-output loops suggest that the pulvinar may regulate the flow of information within and between cortical areas in a highly dynamic fashion. Therefore, understanding the anatomical subdivisions within the pulvinar, and its connectivity with the cortex, is paramount to understanding pulvinar physiological function. However, there is a stark contrast regarding the way that the pulvinar is subdivided depending on the technique employed. Cytoarchitectural and immunohistochemical methods reveal a very similar pattern of pulvinar subdivision across Old- and New-World monkeys. On the other hand, electrophysiological and connectivity studies expose clear discrepancies in pulvinar organization across primate evolution.
Contents
Chapter 1: introduction -- Chapter 2: Cytoarchitecture and myeloarchitecture of the pulvinar -- Chapter 3: Chemoarchitecture of the pulvinar -- Chapter 4: Visual map representations in the primate pulvinar -- Chapter 5: Connectivity of the pulvinar -- Chapter 6: Reestablishing the chemoarchitectural borders based on electrophysiological and connectivity data -- Chapter 7: Visual topography of the pulvinar projection zones -- Chapter 8: Comparative pulvinar organization across different primate species -- Chapter 9: Response properties of pulvinar neurons studied with single unit electrophysiological recordings -- Chapter 10: Modulation of pulvinar neuronal activity by arousal -- Chapter 11: Gaba inactivation of the pulvinar -- Chapter 12: The role of the pulvinar in spatial visual attention.
Format
e-Book
Location
Online
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Urodynamics for Urogynecologists : A Pocket Guide for Clinical Practice

https://libcat.nshealth.ca/en/permalink/provcat43349
Giancarlo Vignoli. --Cham: Springer , c2018.
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This book offers gynecologists and urogynecologists a pocket guide to urodynamic testing in women with lower urinary tract symptoms. In female urology, the main indications for urodynamics are urinary incontinence, pelvic organ prolapse, urgency-frequency syndrome (also known as overactive bladder), emptying disorders and painful bladder. By collecting quantitative measurements while reproducing the patient's voiding symptoms where appropriate and possible, urodynamics helps to identify the cau…
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Author
Vignoli, Giancarlo
Responsibility
Giancarlo Vignoli
Place of Publication
Cham
Publisher
Springer
Date of Publication
c2018
Physical Description
1 online resource (xix, 236 p.) : 81 illus., 80 illus. in color
ISBN
9783319740058
9783319740041 (print ed.)
9783319740065 (print ed.)
Subjects (MeSH)
Female
Urodynamics
Specialty
Physiology
Urology
Abstract
This book offers gynecologists and urogynecologists a pocket guide to urodynamic testing in women with lower urinary tract symptoms. In female urology, the main indications for urodynamics are urinary incontinence, pelvic organ prolapse, urgency-frequency syndrome (also known as overactive bladder), emptying disorders and painful bladder. By collecting quantitative measurements while reproducing the patient's voiding symptoms where appropriate and possible, urodynamics helps to identify the cause of symptoms, supports management and facilitates prognoses. However, despite the undeniable advantages, the role of urodynamics in female urology is hotly debated. The book starts by describing the physiological background and methodological considerations for urodynamic best practice in the preclinical setting. It then explains how to perform urodynamics correctly—so-called "good urodynamic practice"—to increase the readers' confidence and ability to perform and interpret urodynamic investigations. Lastly, it reviews the advantages and disadvantages of urodynamic testing in each of the key clinical female urology conditions. A separate chapter focuses on the peculiarities of diagnosis and management for female patients with neurogenic bladder. This guide offers a valuable tool for gynecologists, urologists and urogynecologists, as well as a ready source of information for all physicians involved in diagnosing and treating lower urinary tract disorders in women.
Contents
Physiology of micturition in female -- How to perform urodynamic investigation: the good urodynamic practice -- Urodynamics in stress urinary incontinence -- Urodynamics in pelvic prolapse -- Urodynamics in overactive bladder -- Urodynamics in emptying problems -- Urodynamics in chronic pelvic pain -- Neurogenic bladder in female.
Format
e-Book
Location
Online
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Sport and Physical Activity in the Heat : Maximizing Performance and Safety

https://libcat.nshealth.ca/en/permalink/provcat43389
Douglas J. Casa, editor. --Cham: Springer , c2018.
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This unique book is the first of its kind to specifically explore the science, medicine, challenges and successful experiences of assisting those who must perform and thrive in hot conditions, with an eye toward maximizing both performance and safety. Beginning with both human and comparative physiology as it relates to coping with the heat, key concepts are subsequently elaborated, including heat acclimatization, work-to-rest ratios, hydration, sleep, the effects of altitude, and the use of dr…
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Other Authors
Casa, Douglas J.
Responsibility
Douglas J. Casa, editor
Place of Publication
Cham
Publisher
Springer
Date of Publication
c2018
Physical Description
1 online resource (xxiv, 376 p.) : 46 illus., 24 illus. in color
ISBN
9783319702179
9783319702162 (print ed.)
9783319702186 (print ed.)
Subjects (MeSH)
Exercise - physiology
Heat Stress Disorders - prevention & control
Sports - physiology
Thermotolerance - physiology
Specialty
Physiology
Sports Medicine
Abstract
This unique book is the first of its kind to specifically explore the science, medicine, challenges and successful experiences of assisting those who must perform and thrive in hot conditions, with an eye toward maximizing both performance and safety. Beginning with both human and comparative physiology as it relates to coping with the heat, key concepts are subsequently elaborated, including heat acclimatization, work-to-rest ratios, hydration, sleep, the effects of altitude, and the use of drugs and supplements. The sections that follow discuss heat-related considerations in individual and team sports and other populations, monitoring techniques, and medical and legal issues. Athletes, warfighters and laborers are often forced to perform intense physical activity in the heat as a part of their jobs or lifestyle. The process of properly preparing for this challenge is multifaceted and often not fully understood or utilized.áSport and Physical Activity in the Heatáis an excellent resource foráteam physicians, high-level coaches, serious athletes, athletic trainers, exercise scientists, strength and conditioning coaches, industrial hygienists, military commanders, or anyone involved in the process of maximizing performance and safety during exercise in the heat for the athlete, warfighter, or laborer.
Contents
Part I. Foundational Concepts -- 1. Comparative Physiology of Thermoregulation -- 2. Human Heat Physiology -- Part II. Enhancing Exercise Heat Tolerance -- 3. Heat Acclimation -- 4. Body Cooling -- 5. Hydration -- 6. Work-to-Rest Ratio -- 7. Sleep -- 8. Altitude -- Part III. Tools Available to Assist -- 9. Environmental Condition and Monitoring -- 10. Technology -- 11. Biomarkers -- 12. Heat Tolerance Testing -- Part IV. Populations -- 13. Individual Sports -- 14. Team Sports -- 15. Occupational Settings: Considerations for the Laborer -- 16. Military Settings: Considerations for the Warfighter -- Part V. Individual Issues -- 17. Exertional Heat Illnesses -- 18. Other Medical Conditions of Concern During Hot Weather Exercise -- 19. Drugs and Supplements.
Format
e-Book
Location
Online
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Hyperhidrosis : A Complete Guide to Diagnosis and Management

https://libcat.nshealth.ca/en/permalink/provcat43399
Marcelo de Paula Loureiro, José Ribas M. de Campos, Nelson Wolosker, Paulo Kauffman, editors. --Cham: Springer , c2018.
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Location
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Hyperhidrosis is a medical condition in which a person sweats excessively and unpredictably. People with hyperhidrosis may sweat even when the temperature is cool or when they are at rest. Despite prevalence of at least 1% of the global population, Hyperhidrosis is still an unknown entity, for the most part -- an undertreated and even neglected medical condition. Moreover, there are few sources summarizing the knowledge on hyperhidrosis to a wider audience. The purpose of this book is to provid…
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Other Authors
Loureiro, Marcelo de Paula
de Campos, José Ribas M.
Wolosker, Nelson
Kauffman, Paulo
Responsibility
Marcelo de Paula Loureiro, José Ribas M. de Campos, Nelson Wolosker, Paulo Kauffman, editors
Place of Publication
Cham
Publisher
Springer
Date of Publication
c2018
Physical Description
1 online resource (xiv, 285 p.) : 72 illus., 71 illus. in color
ISBN
9783319895277
9783319895260 (print ed.)
9783319895284 (print ed.)
Subjects (MeSH)
Hyperhidrosis - diagnosis
Hyperhydrosis - therapy
Specialty
Dermatology
Physiology
Abstract
Hyperhidrosis is a medical condition in which a person sweats excessively and unpredictably. People with hyperhidrosis may sweat even when the temperature is cool or when they are at rest. Despite prevalence of at least 1% of the global population, Hyperhidrosis is still an unknown entity, for the most part -- an undertreated and even neglected medical condition. Moreover, there are few sources summarizing the knowledge on hyperhidrosis to a wider audience. The purpose of this book is to provide information regarding hyperhidrosis, ranging from basic information on pathophysiology to the most advanced therapeutic alternatives. From a therapeutic perspective, hyperhidrosis requires clinical treatment using topical and subdermal agents as well as surgical approaches. The book will not only cover these topics but will discuss all aspects of care -- from patient selection through post-surgical complications. Special attention will be given to sympathectomies. Medical and paramedical professionals, as well as students and researchers, interested in the topic will find the book comprehensive in scope and targeted in offering practical, clinical guidance. Diagnosis and Treatment of Hyperhidrosis: A Complete Guide counts with the collaboration of most renowned specialists of this field, and is intended as an easy to read and very practical reference book.
Contents
Part I. The Patient with Hyperhidrosis -- Anatomy of the Sudoripar Glands -- Secondary Hyperhidrosis: Endocrinopathies and Hyperhidrosis -- Hyperhidrosis and obesity -- Primary Hyperhidrosis -- The Prevalence of Hyperhidrosis Worldwide -- Hyperhidrosis in Children -- The Psychological Profile of the Patient with Primary Hyperhidrosis -- Psychiatric Features in Hyperhidrosis -- Anxiety, Depression and Hyperhidrosis -- Hyperhidrosis and Diet Induced Thermogenesis -- Constraints Caused by Primary Hyperhidrosis -- Part II. General Treatment of Hyperhidrosis -- Pharmacological Treatment of Hyperhidrosis -- Hyperhidrosis, Its Deep Consequences in People and Its Topical Treatment -- Axillary Hyperhidrosis and Bromidrosis: The Dermatologist's Point of View -- Botulinum Toxin for Axillary and Palmar Hyperhidrosis -- Axillary Hyperhidrosis: Surgical Local Treatment with Aspiratory Curettage -- Part III. Sympathectomies for Hyperhidrosis -- Anatomy of the Sympathetic Nervous System Correlations with the Surgical Hyperhidrosis Treatment -- Criteria for Surgical Patient Selection -- Surgical Techniques for the Realization of Thoracic Sympathectomy -- Bilateral Thoracic Sympathectomy: How I Do It? -- Endoscopic Thoracic Sympathectomy (ETS) for Primary Palmar Hyperhidrosis -- Evolution of Surgical Tactics and Difficulties of ETS -- Is the Clipping Method for Sympathetic Nerve Surgery a Reversible Procedure? -- Surgical Difficulties and Complications of Video-Assisted Thoracoscopic for Thoracic Sympathectomy -- Outpatient Clinic for Patients with Hyperhidrosis -- Management of Compensatory Hyperhidrosis -- Endoscopic Lumbar Sympathectomy in the Treatment of Hyperhidrosis: Technical Aspects -- Endoscopic Lumbar Sympathectomy: Results and Complications -- Part IV. Blushing -- Facial Blushing : Psychiatric Management -- Approach and Selection of the Patients with Facial Blushing for Surgery -- ETS for Facial Blushing and Craniofacial Hyperhidrosis -- Part V. Final -- Quality of Life Evaluation During Treatment of Hyperhidrosis -- Ethical-legal Aspects of the Management of Hyperhidrosis -- Questions And Answers About Hyperhidrosis, Treatment And Consequences.
Format
e-Book
Location
Online
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Respiratory physiology

https://libcat.nshealth.ca/en/permalink/provcat43759
Michelle M. Cloutier. (2nd ed.) --Philadelphia, PA: Elsevier , c2019.
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Gain a foundational understanding of respiratory physiology and how the respiratory system functions in health and disease. Respiratory Physiology, a volume in the Mosby Physiology Series, explains the fundamentals of this complex subject in a clear and concise manner, while helping you bridge the gap between normal function and disease with pathophysiology content throughout the book.
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Author
Cloutier, Michelle M.
Responsibility
Michelle M. Cloutier
Edition
2nd ed.
Place of Publication
Philadelphia, PA
Publisher
Elsevier
Date of Publication
c2019
Physical Description
1 online resource (196 p.)
Series
Mosby physiology series
ISBN
9780323595780
Subjects (MeSH)
Respiratory Physiological Phenomena
Specialty
Pulmonary Medicine
Physiology
Abstract
Gain a foundational understanding of respiratory physiology and how the respiratory system functions in health and disease. Respiratory Physiology, a volume in the Mosby Physiology Series, explains the fundamentals of this complex subject in a clear and concise manner, while helping you bridge the gap between normal function and disease with pathophysiology content throughout the book.
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Format
e-Book
Location
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A Time for Metabolism and Hormones

https://libcat.nshealth.ca/en/permalink/provcat43932
Paolo Sassone-Corsi, Yves Christen, editors. --Cham: SpringerOpen , c2016.
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Open access
Location
Online
Recent years have seen spectacular advances in the field of circadian biology. These have attracted the interest of researchers in many fields, including endocrinology, neurosciences, cancer, and behavior. By integrating a circadian view within the fields of endocrinology and metabolism, researchers will be able to reveal many, yet-unsuspected aspects of how organisms cope with changes in the environment and subsequent control of homeostasis. This field is opening new avenues in our understandi…
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Other Authors
Sassone-Corsi, Paolo
Christen, Yves
Responsibility
Paolo Sassone-Corsi, Yves Christen, editors
Place of Publication
Cham
Publisher
SpringerOpen
Date of Publication
c2016
Physical Description
1 online resource (xiii, 132 p.) : 28 illus., 26 illus. in color.
Series Title
Research and perspectives in endocrine interactions
ISBN
9783319270692
9783319270685 (Print ed.)
9783319270708 (Print ed.)
9783319800677 (Print ed.)
ISSN
1861-2253
Subjects (MeSH)
Circadian Clocks - physiology
Circadian rhythm - physiology
Metabolism - physiology
Specialty
Endocrinology
Physiology
Abstract
Recent years have seen spectacular advances in the field of circadian biology. These have attracted the interest of researchers in many fields, including endocrinology, neurosciences, cancer, and behavior. By integrating a circadian view within the fields of endocrinology and metabolism, researchers will be able to reveal many, yet-unsuspected aspects of how organisms cope with changes in the environment and subsequent control of homeostasis. This field is opening new avenues in our understanding of metabolism and endocrinology. A panel of the most distinguished investigators in the field gathered together to discuss the present state and the future of the field. The editors trust that this volume will be of use to those colleagues who will be picking up the challenge to unravel how the circadian clock can be targeted for the future development of specific pharmacological strategies toward a number of pathologies.
Contents
The epigenetic and metabolic language of the circadian clock -- Molecular architecture of the circadian clock in mammals -- Circadian mechanisms in bioenergetics and cell metabolism -- Control of metabolism by central and peripheral clocks in Drosophila -- Circadian post-transcriptional control of metabolism -- Redox and metabolic oscillations in the clockwork -- Rev-erbs: integrating metabolism around the clock -- Control of sleep-wake cycles in Drosophila -- Circadian metabolomics: insights for biology and medicine -- Rhythms within rhythms: the importance of oscillations for glucocorticoid hormones -- The genetics of autism spectrum disorders.
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Open access
Format
e-Book
Location
Online
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Hormones, Metabolism and the Benefits of Exercise

https://libcat.nshealth.ca/en/permalink/provcat43933
Bruce Spiegelman, editor. --Cham: SpringerOpen , c2017.
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Location
Online
The world is faced with an epidemic of metabolic diseases such as obesity and type 2 diabetes. This is due to changes in dietary habits and the decrease in physical activity. Exercise is usually part of the prescription, the first line of defense, to prevent or treat metabolic disorders. However, we are still learning how and why exercise provides metabolic benefits in human health. This open access volume focuses on the cellular and molecular pathways that link exercise, muscle biology, hormon…
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Other Authors
Spiegelman, Bruce M.
Other Authors
Fondation IPSEN pour la recherche thérapeutique
Responsibility
Bruce Spiegelman, editor
Place of Publication
Cham
Publisher
SpringerOpen
Date of Publication
c2017
Physical Description
1 online resource (x, 102 p.) : ill. (some col.)
Series Title
Research and perspectives in endocrine interactions
ISBN
9783319727905
9783319727899 (Print ed.)
9783319727912 (Print ed.)
9783030102685 (Print ed.)
ISSN
1861-2253
Subjects (MeSH)
Exercise - physiology
Hormones - physiology
Metabolism - physiology
Specialty
Biochemistry
Endocrinology
Physiology
Abstract
The world is faced with an epidemic of metabolic diseases such as obesity and type 2 diabetes. This is due to changes in dietary habits and the decrease in physical activity. Exercise is usually part of the prescription, the first line of defense, to prevent or treat metabolic disorders. However, we are still learning how and why exercise provides metabolic benefits in human health. This open access volume focuses on the cellular and molecular pathways that link exercise, muscle biology, hormones and metabolism. This will include novel “myokines” that might act as new therapeutic agents in the future.
Contents
Human brown adipose tissue plasticity: hormonal and environmental manipulation -- The energy sensor AMPK: adaptations to exercise, nutritional and hormonal signals -- Plasma steroids and cardiorespiratory fitness response to regular exercise -- Sending the signal: muscle glycogen availability as a regulator of training adaptation -- Optimized engagement of macrophages and satellite cells in the repair and regeneration of exercised muscle -- Skeletal muscle microRNAs: roles in differentiation, disease and exercise -- Tryptophan-kynurenine metabolites in exercise and mental health -- The role of FNDC5/irisin in the nervous system and as a mediator for beneficial effects of exercise on the brain.
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Format
e-Book
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Online
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