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Applications of FDG PET in Oncology : Best Clinical Practice

https://libcat.nshealth.ca/en/permalink/provcat46492
Hirofumi Fujii, Hiroyuki Nakamura, Seiei Yasuda, editors. --Singapore: Springer , c2021.
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This book provides up-to-date guidance on the use of FDG PET to assess the biological activity and treatment response of a wide range of malignancies, including, for example, lung cancer, breast cancer, head and neck cancer, gastrointestinal cancer, and malignant lymphoma. In the era of precision medicine, numerous new anticancer agents, such as molecular targeted agents and immune checkpoint inhibitors, have been developed to improve outcomes in cancer patients. FDG PET plays a key role in eva…
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Other Authors
Fujii, Hirofumi
Nakamura, Hiroyuki
Yasuda, Seiei
Responsibility
Hirofumi Fujii, Hiroyuki Nakamura, Seiei Yasuda, editors
Place of Publication
Singapore
Publisher
Springer
Date of Publication
c2021
Physical Description
1 online resource (vii, 147 p.) : 61 illus., 55 illus. in color
ISBN
9789811584237
9789811584220 (Print ed.)
9789811584244 (Print ed.)
9789811584251 (Print ed.)
Subjects (MeSH)
Neoplasms - diagnostic imaging
Positron-Emission Tomography
Radionuclide Imaging
Specialty
Diagnostic Imaging
Medical Oncology
Abstract
This book provides up-to-date guidance on the use of FDG PET to assess the biological activity and treatment response of a wide range of malignancies, including, for example, lung cancer, breast cancer, head and neck cancer, gastrointestinal cancer, and malignant lymphoma. In the era of precision medicine, numerous new anticancer agents, such as molecular targeted agents and immune checkpoint inhibitors, have been developed to improve outcomes in cancer patients. FDG PET plays a key role in evaluating the effects of these novel treatments because it can detect changes in the metabolic activity of tumors before any reduction in their size is visible on other imaging modalities. Accordingly, FDG PET is of prognostic as well as diagnostic value, and allows prompt changes in patient management. The book is written by expert clinicians from Japan, where the universal public health insurance system ensures that FDG PET is widely used in routine oncological practice and cancer screening. It represents an unrivaled and comprehensive resource that will be of value for all healthcare professionals in the field of clinical oncology.
Contents
1. Overview of FDG PET in Oncology in Japan -- 2. The Role of 18F-FDG-PET as Therapeutic Monitoring in Patients with Lung Cancer -- 3. F-18 FDG PET Tests in Breast Cancer -- 4. F-18 FDG PET Tests in Head and Neck Cancer -- 5. Positron Emission Tomography/Computed Tomography in Colorectal Cancer -- 6. Urological Cancer -- 7. Bone and Soft-Tissue Tumors -- 8. F-18 FDG PET Tests in Skin Cancer Including Malignant Melanoma -- 9. F-18 FDG PET Tests in Malignant Lymphoma.
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NEW Springer 2021
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e-Book
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Atlas and Anatomy of PET/MRI, PET/CT and SPECT/CT

https://libcat.nshealth.ca/en/permalink/provcat40100
E. Edmund Kim, Hyung-jun Im, Dong Soo Lee, Keon Wook Kang. --Cham: Springer , c2016.
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This atlas showcases cross-sectional anatomy for the proper interpretation of images generated from PET/MRI, PET/CT, and SPECT/CT applications. Hybrid imaging is at the forefront of nuclear and molecular imaging and enhances data acquisition for the purposes of diagnosis and treatment. Simultaneous evaluation of anatomic and metabolic information about normal and abnormal processes addresses complex clinical questions and raises the level of confidence of the scan interpretation. Extensively il…
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Author
Kim, E. Edmund
Other Authors
Im, Hyung-jun
Lee, Dong Soo
Kang, Keon Wook
Responsibility
E. Edmund Kim, Hyung-jun Im, Dong Soo Lee, Keon Wook Kang
Place of Publication
Cham
Publisher
Springer
Date of Publication
c2016
Physical Description
1 online resource (xi, 594 p. : 582 illus. in color)
ISBN
9783319286525
9783319286501 (print ed.)
Subjects (MeSH)
Anatomy
Magnetic Resonance Imaging
Multimodal Imaging
Positron-Emission Tomography
Tomography, X-Ray Computed
Abstract
This atlas showcases cross-sectional anatomy for the proper interpretation of images generated from PET/MRI, PET/CT, and SPECT/CT applications. Hybrid imaging is at the forefront of nuclear and molecular imaging and enhances data acquisition for the purposes of diagnosis and treatment. Simultaneous evaluation of anatomic and metabolic information about normal and abnormal processes addresses complex clinical questions and raises the level of confidence of the scan interpretation. Extensively illustrated with high-resolution PET/MRI, PET/CT and SPECT/CT images, this atlas provides precise morphologic information for the whole body as well as for specific regions such as the head and neck, abdomen, and musculoskeletal system. Atlas and Anatomy of PET/MRI, PET/CT, AND SPECT/CT is a unique resource for physicians and residents in nuclear medicine, radiology, oncology, neurology, and cardiology.
Contents
Atlas and Anatomy of PET/MR -- Atlas and Anatomy of PET/CT -- Atlas and Anatomy of SPECT/CT.
Format
e-Book
Publication Type
Atlas
Location
Online
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Atlas of PET-CT : A Quick Guide to Image Interpretation

https://libcat.nshealth.ca/en/permalink/provcat43824
Stefano Fanti, Mohsen Farsad, Luigi Mansi, Paolo Castellucci. (Second edition) --Berlin, Heidelberg: Springer , c2018.
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This new atlas, the fourth of a successful series, is a completely revised and updated edition of a previously published FDG PET-CT atlas. In the past few years, considerable progress has been made in the field of PET-CT imaging, and this new edition takes full account of these recent developments. Furthermore, its educational mission has been broadened: beyond serving as a straightforward guide to FDG PET-CT imaging it now encompasses the integrative use of contrast-enhanced CT and MRI. The ne…
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Author
Fanti, Stefano
Other Authors
Farsad, Mohsen
Mansi, Luigi
Castellucci, Paolo
Responsibility
Stefano Fanti, Mohsen Farsad, Luigi Mansi, Paolo Castellucci
Edition
Second edition
Place of Publication
Berlin, Heidelberg
Publisher
Springer
Date of Publication
c2018
Physical Description
1 online resource (xv, 365 p. : 784 illus., 514 illus. in color)
ISBN
9783662577424
9783662577400 (Print ed.)
9783662577417 (Print ed.)
Subjects (MeSH)
Neoplasms - diagnostic imaging
Positron-Emission Tomography
Tomography, Emission-Computed
Specialty
Diagnostic Imaging
Abstract
This new atlas, the fourth of a successful series, is a completely revised and updated edition of a previously published FDG PET-CT atlas. In the past few years, considerable progress has been made in the field of PET-CT imaging, and this new edition takes full account of these recent developments. Furthermore, its educational mission has been broadened: beyond serving as a straightforward guide to FDG PET-CT imaging it now encompasses the integrative use of contrast-enhanced CT and MRI. The new edition also includes non-oncological indications for FDG PET-CT. The atlas aims to help imaging practitioners to recognize physiological and benign pathological FDG uptake and illustrates in a case-based, practical manner the PET-CT appearances of all the major tumors and infectious, inflammatory, and neurodegenerative disorders. The main clinical applications are covered, and learning points and pitfalls are clearly articulated. The consistent, user-friendly format facilitates image interpretation and allows rapid review of key information needed for FDG PET-CT imaging.
Contents
Part 1. Introduction -- 1. Premises to PET/CT with FDG in Oncology -- 2. Normal Distribution, Variants, and Artifacts (Versus Pathological Uptake in Malignant and Benign Diseases) -- Part 2. FDG PET/CT in Oncology -- 3. Malignancies in Hematology -- 4. Malignancies in Dermatology -- 5. Thoracic Malignancies -- 6. Breast Cancer -- 7. Head and Neck Malignancies -- 8. Gynecological Malignancies -- 9. Esophageal Cancer -- 10. Malignancies of Lower Gastroenterological Tract -- 11. Urological Malignancies -- 12. Malignancy in Orthopedics -- 13. Cancers of Unknown Origin -- Part 3. FDG PET/CT in Non Oncological Diseases -- 14. Infection and Inflammation -- 15. Brain 18F-Fluorodeoxyglucose (FDG) PET.
Format
e-Book
Publication Type
Atlas
Case Reports
Location
Online
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Atlas of PET-CT Imaging in Oncology : A Case-Based Guide to Image Interpretation

https://libcat.nshealth.ca/en/permalink/provcat39331
Tamer Özülker, Filiz Özülker. --Cham: Springer , c2015.
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This atlas is a case-based guide to the interpretation of FDG PET-CT images in clinical scenarios faced by physicians during the routine practice of oncology. The book aims to help the practitioner to overcome diagnostic dilemmas through familiarization with the physiologic distribution of FDG, normal variants, and benign findings. It includes a rich variety of atypical incidental findings which are rarely seen but may give rise to inconclusive reports. The main focus, however, is the imaging o…
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Author
Özülker, Tamer
Other Authors
Özülker, Filiz
Responsibility
Tamer Özülker, Filiz Özülker
Place of Publication
Cham
Publisher
Springer
Date of Publication
c2015
Physical Description
1 online resource (xxiii, 469 p. : 481 illus., 283 illus. in color)
ISBN
9783319189949
9783319189932 (print ed.)
Subjects (MeSH)
Multimodal Imaging
Neoplasms - diagnosis
Neoplasms - therapy
Positron-Emission Tomography
Tomography, X-Ray Computed
Abstract
This atlas is a case-based guide to the interpretation of FDG PET-CT images in clinical scenarios faced by physicians during the routine practice of oncology. The book aims to help the practitioner to overcome diagnostic dilemmas through familiarization with the physiologic distribution of FDG, normal variants, and benign findings. It includes a rich variety of atypical incidental findings which are rarely seen but may give rise to inconclusive reports. The main focus, however, is the imaging of major oncological diseases, including the rare ones. Different pathologies are addressed in individual chapters comprising teaching files of cases, each of which corresponds to a common indication for PET-CT imaging. These indications include metabolic characterization of lesions, detection of an unknown primary, staging, restaging, and evaluation of response to therapy. Each case is accompanied by a succinct explanation of the patient's history, interpretation of the PET-CT study, and a teaching point which is often supported by relevant literature. This book will be of great value to residents and practitioners in nuclear medicine, radiology, oncology, radiation oncology, and nuclear medicine technology.
Contents
Part I. Fundamentals -- 1 Physiologic Distribution of 18F-FDG -- 2 Normal Variants and Benign Findings -- Part II. PET/CT in Oncology -- 3 Head and Neck Cancer -- 4 Thyroid Cancer -- 5 Lung Cancer -- 6 Breast Cancer -- 7 Lymphoma -- 8 Colorectal Cancer -- 9 Gastric and Esophageal Tumors -- 10 Liver Tumors -- 11 Pancreas -- 12 Gastrointestinal Stromal Tumors -- 13 Surrenal Tumors -- 14 Gynecologic Tumors -- 15 Urologic -- 16 Musculoskeletal Tumors -- 17 Skin Cancers -- 18 Miscellaneous.
Format
e-Book
Publication Type
Atlas
Case Reports
Location
Online
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Atlas of PET/CT in pediatric patients

https://libcat.nshealth.ca/en/permalink/provcat33762
Angelina Cistaro, editor. --Milan: Springer , c2014.
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This richly illustrated book presents the pediatric applications of PET/CT in the full range of scenarios frequently encountered in a professional setting. It opens with a thorough introduction covering the fundamental science and the clinical basis for use of PET/CT in this age group. Pitfalls and artifacts are examined, and normal variations and benign findings are carefully described. Each subsequent chapter addresses the role of PET/CT with different radiopharmaceuticals in the evaluation a…
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Other Authors
Cistaro, Angelina
Responsibility
Angelina Cistaro, editor
Place of Publication
Milan
Publisher
Springer
Date of Publication
c2014
Physical Description
1 online resource (xii, 264 pages)
ISBN
9788847053588 (electronic bk.)
9788847053571
Subjects (MeSH)
Positron-Emission Tomography - Atlases
Subjects (LCSH)
Pediatric tomography - Atlases
Positron-Emission Tomography
Child
Infant
Positron-Emission Tomography - Atlases
Nuclear Medicine
Pediatrics
Oncology
Diagnostic Radiology
Abstract
This richly illustrated book presents the pediatric applications of PET/CT in the full range of scenarios frequently encountered in a professional setting. It opens with a thorough introduction covering the fundamental science and the clinical basis for use of PET/CT in this age group. Pitfalls and artifacts are examined, and normal variations and benign findings are carefully described. Each subsequent chapter addresses the role of PET/CT with different radiopharmaceuticals in the evaluation and management of a specific disease. The full range of oncological diseases is covered, including the rare ones. Succinct descriptions of clinical cases are included and, when appropriate, comparisons are made with other modalities. In addition, the role of PET/CT in biopsy guidance and in radiation therapy planning is explained.
Contents
Basic science and practical issues -- Oncology -- Other tumors -- Neurology -- Infection and inflammation -- Other applications.
Format
e-Book
Location
Online
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Atlas of PET/MR Imaging in Oncology

https://libcat.nshealth.ca/en/permalink/provcat40783
Osman Ratib, Markus Schwaiger, Thomas Beyer, editors. --Berlin, Heidelberg: Springer , c2013.
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This new project on PET/MR imaging in oncology includes digital interactive software matching the cases in the book. The interactive version of the atlas is based on the latest web standard, HTML5, ensuring compatibility with any computer operating system as well as a dedicated version for Apple iPad and iPhone. The book opens with an introduction to the principles of hybrid imaging that pays particular attention to PET/MR imaging and standard PET/MR acquisition protocols. A wide range of illus…
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Other Authors
Ratib, Osman
Schwaiger, Markus
Beyer, Thomas
Responsibility
Osman Ratib, Markus Schwaiger, Thomas Beyer, editors
Place of Publication
Berlin, Heidelberg
Publisher
Springer
Date of Publication
c2013
Physical Description
1 online resource (viii, 232 p. : 351 illus., 250 illus. in color)
ISBN
9783642312922
9783642312915 (print ed.)
Subjects (MeSH)
Magnetic Resonance Imaging
Neoplasms - diagnosis
Neoplasms - diagnostic imaging
Positron-Emission Tomography
Radionuclide Imaging
Whole Body Imaging
Abstract
This new project on PET/MR imaging in oncology includes digital interactive software matching the cases in the book. The interactive version of the atlas is based on the latest web standard, HTML5, ensuring compatibility with any computer operating system as well as a dedicated version for Apple iPad and iPhone. The book opens with an introduction to the principles of hybrid imaging that pays particular attention to PET/MR imaging and standard PET/MR acquisition protocols. A wide range of illustrated clinical case reports are then presented. Each case study includes a short clinical history, findings, and teaching points, followed by illustrations, legends, and comments. The multimedia version of the book includes dynamic movies that allow the reader to browse through series of rotating 3D images (MIP or volume rendered), display blending between PET and MR, and dynamic visualization of 3D image volumes. The movies can be played either continuously or sequentially for better exploration of sets of images. The editors of this state-of-the-art publication are key opinion leaders in the field of multimodality imaging. Professor Osman Ratib (Geneva) and Professor Markus Schwaiger (Munich) were the first in Europe to initiate the clinical adoption of PET/MR imaging. Professor Thomas Beyer (Zurich) is an internationally renowned pioneering physicist in the field of hybrid imaging. Individual clinical cases presented in this book are co-authored by leading international radiologists and nuclear physicians experts in the use of PET and MRI.
Contents
Part I. Clinical and Technical Principles -- 1. Introduction -- 2. PET/MR Instrumentation -- 3. Technical Principles and Protocols of PET/MR Imaging -- Part II. PET/MR Atlas of Clinical Cases in Oncology -- 4. Head and Neck Cancers -- 5. Prostate Cancers -- 6. Breast Cancers -- 7. Gynecological Cancers -- 8. Brain Tumors -- 9. Pediatric Oncology -- 10. Lymphoma, Lung and Other Tumors -- 11. Thyroid and Endocrine Tumors -- 12. Benign, Degenerative and Inflammatory Diseases.
Format
e-Book
Publication Type
Atlas
Location
Online
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Basic Science of PET Imaging

https://libcat.nshealth.ca/en/permalink/provcat41358
Magdy M. Khalil, editor. --Cham: Springer , 2017.
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This book offers a wide-ranging and up-to-date overview of the basic science underlying PET and its preclinical and clinical applications in modern medicine. In addition, it provides the reader with a sound understanding of the scientific principles and use of PET in routine practice and biomedical imaging research. The opening sections address the fundamental physics, radiation safety, CT scanning dosimetry, and dosimetry of PET radiotracers, chemistry and regulation of PET radiopharmaceutical…
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Other Authors
Khalil, Magdy M
Responsibility
Magdy M. Khalil, editor
Place of Publication
Cham
Publisher
Springer
Date of Publication
2017
Physical Description
1 online resource (xix, 619 pages) : 150 illus., 100 illus. in color
ISBN
9783319400709
9783319400686 (print ed.)
Subjects (MeSH)
Positron-Emission Tomography
Abstract
This book offers a wide-ranging and up-to-date overview of the basic science underlying PET and its preclinical and clinical applications in modern medicine. In addition, it provides the reader with a sound understanding of the scientific principles and use of PET in routine practice and biomedical imaging research. The opening sections address the fundamental physics, radiation safety, CT scanning dosimetry, and dosimetry of PET radiotracers, chemistry and regulation of PET radiopharmaceuticals, with information on labeling strategies, tracer quality control, and regulation of radiopharmaceutical production in Europe and the United States. PET physics and instrumentation are then discussed, covering the basic principles of PET and PET scanning systems, hybrid PET/CT and PET/MR imaging, system calibration, acceptance testing, and quality control. Subsequent sections focus on image reconstruction, processing, and quantitation in PET and hybrid PET and on imaging artifacts and correction techniques, with particular attention to partial volume correction and motion artifacts. The book closes by examining clinical applications of PET and hybrid PET and their physiological and/or molecular basis in conjunction with technical foundations in the disciplines of oncology, cardiology and neurology, PET in pediatric malignancy and its role in radiotherapy treatment planning. Basic Science of PET Imaging will meet the needs of nuclear medicine practitioners, other radiology specialists, and trainees in these fields.
Contents
Part I: Physics, Radiation Safety and Dosimetry of PET -- 1. Basic Radiation Physics -- 2. Radiation Safety and CT Dosimetry in PET/CT Imaging -- 3. Radiation Dosimetry of PET Imaging -- Part II: PET Chemistry and Regulation of PET Radiopharmaceuticals -- 4. Chemistry of PET Radiopharmaceuticals: Labelling Strategies -- 5. Quality Control of PET Radiopharmaceuticals -- 6. Regulation of PET Radiopharmaceuticals Production in Europe -- 7. Regulatory Aspects of PET Radiopharmaceutical Production in the United States -- Part III: PET Physics and Instrumentation -- 8. PET Physics and Instrumentation -- 9. PET/MR: Basics and New Developments -- 10. PET Calibration, Acceptance Testing, and Quality Control -- Part IV: PET Image Reconstruction, Processing and Quantitation -- 11. PET Image Reconstruction: Methodology and Quantitative Accuracy -- 12. Image Processing and Analysis of PET and Hybrid PET Imaging -- 13. Basics and Advances of Quantitative PET Imaging -- 14. Compartmental Modeling in PET Kinetics -- Part V: PET Imaging Artifacts and Correction Techniques -- 15. Partial Volume Correction in PET Imaging -- 16. Motion Artifacts and Correction Techniques in PET/CT -- Part VI: Scientific and Clinical Basis of PET Applications -- 17. Physiologic and Molecular Basis of PET in Cancer Imaging -- 18. Clinical Applications of PET/CT in Oncology -- 19. Cardiac PET Imaging: Principles and New Developments -- 20. PET in Neurological and Psychiatric Disorders: Technologic Advances and Clinical Applications -- 21. Role of PET/CT in Pediatric Malignancy -- 22. Role of PET/CT in Radiotherapy Treatment Planning.
Format
e-Book
Location
Online
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Functional Brain Tumor Imaging

https://libcat.nshealth.ca/en/permalink/provcat39557
Jay J. Pillai, editor. --New York, NY: Springer , c2014.
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This book presents a comprehensive overview of current state-of-the-art clinical physiological imaging of brain tumors. It focuses on the clinical applications of various modalities as they relate to brain tumor imaging, including techniques such as blood oxygen level dependent functional magnetic resonance imaging, diffusion tensor imaging, magnetic source imaging/magnetoencephalography, magnetic resonance perfusion imaging, magnetic resonance spectroscopic imaging, amide proton transfer imagi…
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Other Authors
Pillai, Jay J
Responsibility
Jay J. Pillai, editor
Place of Publication
New York, NY
Publisher
Springer
Date of Publication
c2014
Physical Description
1 online resource (xiii, 250 p. : 125 illus., 101 illus. in color)
ISBN
9781441958587
9781441958570 (print ed.)
Subjects (MeSH)
Brain Neoplasms - diagnostic imaging
Functional Neuroimaging
Magnetic Resonance Imaging
Positron-Emission Tomography
Abstract
This book presents a comprehensive overview of current state-of-the-art clinical physiological imaging of brain tumors. It focuses on the clinical applications of various modalities as they relate to brain tumor imaging, including techniques such as blood oxygen level dependent functional magnetic resonance imaging, diffusion tensor imaging, magnetic source imaging/magnetoencephalography, magnetic resonance perfusion imaging, magnetic resonance spectroscopic imaging, amide proton transfer imaging, high angular resolution diffusion imaging, sodium imaging, and molecular imaging. Featuring contributions from renowned experts in functional imaging, this book examines the diagnosis and characterization of brain tumors, details the application of functional imaging to treatment planning and monitoring of therapeutic intervention, and explores future directions in physiologic brain tumor imaging. Intended for neuro-oncologists, neurosurgeons, neuroradiologists, residents, and medical students, Functional Brain Tumor Imaging is a unique resource that serves to advance patient care and research in this rapidly developing field.
Contents
Part I. Diagnosis and Characterization of Brain Tumors -- MR perfusion imaging: ASL, T2* DSC and T1 DCE methods -- Diffusion Tensor Imaging -- Molecular imaging -- Role of PET in Neuro-Oncology -- MR Spectroscopic Imaging -- Part II. Physiologic Imaging for Planning and Monitoring of Therapeutic Intervention -- BOLD fMRI for Pre-surgical Planning -- BOLD fMRI for Pre-surgical Planning -- DTI for Pre-surgical Planning -- MSI/MEG for Pre-surgical Planning -- Role of BOLD and DTI in Radiation Therapy Planning -- BOLD and DTI Assessment of Brain Plasticity -- MR Perfusion Imaging for Monitoring Treatment Response -- MR Spectroscopic Imaging Role in Assessing Tumor Progression vs. Treatment Effects -- PET Role in Assessing Tumor Progression vs. Treatment Effects -- Role of MRSI and PET in Assessing Therapeutic Response -- Part III. Future Directions in Physiologic Brain Tumor Imaging -- Role of Novel MR Perfusion Sequences in Brain Tumor Imaging: VASO, iVASO, APT -- Evolving Role of BOLD Imaging in Monitoring Therapeutic Intervention -- Advanced Diffusion Imaging: HARDI, DSI, New Approaches to Fiber Tracking -- Ultra-High Field Diffusion Imaging -- Ultra-High Field MRSI -- Ultra-High Field Non-Proton Magnetic Resonance Imaging, including Sodium Imaging -- Future Clinical Applications of Molecular Imaging: Nanoparticles, Cellular Probes, Imaging of Gene Expression -- Future Role of MSI/MEG in Brain Tumor Research.
Format
e-Book
Location
Online
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Handbook of nuclear cardiology : cardiac SPECT and cardiac PET

https://libcat.nshealth.ca/en/permalink/provcat32319
Gary V. Heller, Robert C. Hendel, editors. --London: Springer , c2013.
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Nuclear cardiology procedures have been a mainstay in non-invasive testing for the diagnosis and risk stratification of coronary artery disease for many years. Although a mature field with a multitude of clinical applications, the advances in agents and imaging procedures have been remarkable and important to document. Handbook of Nuclear Cardiology: Cardiac SPECT and Cardiac PET reviews the important indications for nuclear cardiology procedures, and provides a description of the procedures th…
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Other Authors
Heller, Gary V
Hendel, Robert C
Responsibility
Gary V. Heller, Robert C. Hendel, editors
Place of Publication
London
Publisher
Springer
Date of Publication
c2013
Physical Description
1 online resource (xiii, 221 p. : 85 ill., 47 ill. in color)
ISBN
9781447129455
Subjects (MeSH)
Cardiovascular Diseases - diagnostic imaging
Heart - diagnostic imaging - Handbooks
Positron-Emission Tomography
Radiopharmaceuticals - pharmacology
Tomography, Emission-Computed, Single-Photon
Subjects (LCSH)
Cardiology
Abstract
Nuclear cardiology procedures have been a mainstay in non-invasive testing for the diagnosis and risk stratification of coronary artery disease for many years. Although a mature field with a multitude of clinical applications, the advances in agents and imaging procedures have been remarkable and important to document. Handbook of Nuclear Cardiology: Cardiac SPECT and Cardiac PET reviews the important indications for nuclear cardiology procedures, and provides a description of the procedures themselves, including both SPECT and the newer PET imaging protocols as well as key references. The book emphasizes how noninvasive testing results can be used clinically and the appropriateness of such techniques. The editors and their contributors present critical clinical information on cardiac SPECT and PET within a concise and logical structure, which will be vital for trainees, practicing physicians, nurses and technologists looking for a brief, up-to-date overview and reference volume for nuclear cardiology.
Contents
SECTION I: Ordering the Test: Nuclear Cardiology Procedures -- 1.SPECT R. Hendel -- 2. PET J. Lundbye -- SECTION II. Patient Selection, Which Patient? -- 3.Overview of guidelines and appropriate use of criteria - K. Nelson and R. Hendel -- 4.Suspected coronary artery disease: symptomatic, asymptomatic, ED Imaging R. Ruffin and G. Heller -- 5.Patients with CAD: Post MI, Post revascularization (CABG/PCI), stable CAD D. Barmpouletos and G. Heller -- 6.Preoperative evaluation Moreno and R. Hendel -- 7.Patients with heart failure S. Nair and G. Heller -- 8.Unique populations: Diabetes, women, chronic renal failure, elderly - R. Pullatt and G. Heller -- SECTION III. Test performance: How to do it -- 9.Exercise stress testing J. Dawson and R. Hendel -- 10.Pharmacologic Stress Testing A. Badheka and R. Hendel -- 11.SPECT Radiopharmaceuticals - V. Tandon, N. Gauthier, C. Bensimon, T. Ruddy -- 12.SPECT Instrumentation - J. Strydhorst, R.A. Davies, Glenn Wells -- 13.PET Radiopharmaceuticals (A. C. Valadiva, T. Hadizad, J. DaSilva) -- 14.PET Instrumentation J. Renaud, R. Beanlands, RA deKemp -- 15.Radiation safety (dosimetry and impact of serial testing) - G. mall, B. Chow, R. Hessian -- SECTION IV. Test results: What do they mean? -- 16.Interpretation and Reporting of SPECT Myocardial Perfusion Imaging R. Hendel -- 17.Risk stratification and management of Ischemic Heart Disease with Nuclear Cardiology T. Tanawuttiwat and R. Hendel -- SECTION V. Comparative effectiveness of Nuclear Cardiology -- 18. Exercise tolerance testing A. Malik and G. Heller -- 19.Echocardiography M. Tracy and R. Hendel -- 20.Cardiac CT T. Azemi and G. Heller, MD -- 21.Cardiac MRI T. Azemi and G. Heller -- 22.Cardiac Catheterization A. Malik and G. Heller -- Index.
Format
e-Book
Location
Online
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Hybrid PET/CT and SPECT/CT Imaging : A Teaching File

https://libcat.nshealth.ca/en/permalink/provcat29385
edited by Dominique Delbeke, Ora Israel. --New York, NY: Springer-Verlag , c2010.
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Location
Online
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Author
Delbeke, Dominique
Other Authors
Israel, Ora
Responsibility
edited by Dominique Delbeke, Ora Israel
Place of Publication
New York, NY
Publisher
Springer-Verlag
Date of Publication
c2010
ISBN
9780387928203
Subjects (MeSH)
Neoplasms - diagnostic imaging
Positron-Emission Tomography
Radionuclide Imaging
Tomography, Emission-Computed, Single-Photon
Subjects (LCSH)
Oncology
Diagnostic Imaging
Format
e-Book
Location
Online
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Nuclear medicine and PET : technology and techniques

https://libcat.nshealth.ca/en/permalink/provcat21543
Christian, Paul E. (5th ed.) --St. Louis, MO: Mosby , 2004.
Call Number
WN 206 N964 2004
Location
Halifax Infirmary
Call Number
WN 206 N964 2004
Author
Christian, Paul E
Other Authors
Bernier, Donald
Langan, James K
Edition
5th ed.
Place of Publication
St. Louis, MO
Publisher
Mosby
Date of Publication
2004
Physical Description
618 p.
ISBN
0323019641
Subjects (MeSH)
Nuclear Medicine
Positron-Emission Tomography
Format
Book
Location
Halifax Infirmary
Loan Period
3 weeks
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PET and SPECT in neurology

https://libcat.nshealth.ca/en/permalink/provcat33601
Rudi A.J.O. Dierckx, Andreas Otte, Erik F.J. Vries, Aren Waarde, editors ; Klaus L. Leenders, guest editor. --Heidelberg: Springer , c2014.
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PET and SPECT in Neurology highlights the combined expertise of renowned authors whose dedication to the investigation of neurological disorders through nuclear medicine technology has achieved international recognition. Classical neurodegenerative disorders are discussed as well as cerebrovascular disorders, brain tumors, epilepsy, head trauma, coma, sleeping disorders, and inflammatory and infectious diseases of the CNS. The latest results in nuclear brain imaging are detailed. Most chapters …
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Other Authors
Dierckx, Rudi A. J. O
Otte, Andreas P
Vries, Erik F J de
Waarde, Aren van
Leenders, K. L
Responsibility
Rudi A.J.O. Dierckx, Andreas Otte, Erik F.J. Vries, Aren Waarde, editors ; Klaus L. Leenders, guest editor
Place of Publication
Heidelberg
Publisher
Springer
Date of Publication
c2014
Physical Description
1 online resource (xxvi, 1112 pages)
ISBN
9783642543074 (electronic bk.)
9783642543067
Subjects (MeSH)
Neuroimaging
Positron-Emission Tomography
Tomography, Emission-Computed, Single-Photon
Subjects (LCSH)
Nervous system - Diseases - Tomography
Tomography, Emission
Nuclear Medicine
Neurology
Abstract
PET and SPECT in Neurology highlights the combined expertise of renowned authors whose dedication to the investigation of neurological disorders through nuclear medicine technology has achieved international recognition. Classical neurodegenerative disorders are discussed as well as cerebrovascular disorders, brain tumors, epilepsy, head trauma, coma, sleeping disorders, and inflammatory and infectious diseases of the CNS. The latest results in nuclear brain imaging are detailed. Most chapters are written jointly by a clinical neurologist and a nuclear medicine specialist to ensure a multidisciplinary approach. This state-of-the-art compendium will be valuable to anybody in the field of neuroscience, from the neurologist and the radiologist/nuclear medicine specialist to the interested general practitioner and geriatrician. It is the second volume of a trilogy on PET and SPECT imaging in the neurosciences, the other volumes covering PET and SPECT in psychiatry and in neurobiological systems.
Contents
Nuclear Medicine Imaging Tracers for Neurology -- ¹F-Fluorodeoxyglucose PET Procedures: Health Economic Aspects in Neurology -- Tracer Kinetic Modelling -- Quantification in Brain SPECT: Noninvasive Cerebral Blood Flow Measurements Using mTc-Labeled Tracers -- MRI/PET Brain Imaging -- An Investigation of Statistical Power of [¹O]-HO PET Perfusion Imaging: The Influence of Delay and Time Interval -- Molecular Imaging Using Magnetic Resonance Spectroscopy in Neurology: The Past, the Present, and the Future -- The Default Network of the Brain -- Dementia Due to Neurodegenerative Disease: Molecular Imaging Findings -- A Imaging in Aging, Alzheimer's Disease and Other Neurodegenerative Conditions -- PET Imaging of the a42* Nicotinic Acetylcholine Receptors in Alzheimer's Disease -- Neuroimaging Findings in Mild Cognitive Impairment -- Impact of the IWG/Dubois Criteria for Alzheimer's Disease in Imaging Studies -- Perfusion SPECT: Its Role in the Diagnosis and Differential Diagnosis of Alzheimer's Disease, with Particular Emphasis on Guidelines -- Nuclear Imaging in Frontotemporal Dementia -- Parkinson Dementia: PET Findings -- SPECT/PET Findings in Lewy Body Dementia -- Vascular Dementia -- Value of MIBG in the Differential Diagnosis of Neurodegenerative Disorders -- Linking Molecular Neurobiology to Therapeutic Approaches for Alzheimer's Disease with PET -- PET and SPECT Studies of Ageing and Cardiovascular Risk Factors for Alzheimer's Disease -- Carotid Plaque Imaging with SPECT/CT and PET/CT -- PET in Brain Arteriovenous Malformations and Cerebral Proliferative Angiopathy -- Transient Ischaemic Attack (Neuroimaging Findings) -- PET Reveals Pathophysiology in Ischemic Stroke -- Parkinson's Disease -- SPECT Imaging for Idiopatic M. Parkinson and Parkinsonian Syndromes: Guidelines and Comparison with PET and Recent Developments -- PET and SPECT Imaging in Parkinsonian Syndromes -- Amyotrophic Lateral Sclerosis -- PET in Huntington's Disease -- PET and SPECT Imaging in Dystonia -- PET and SPECT Imaging in Hyperkinetic Movement Disorders -- Clinical Applications of [¹²³I]FP-CIT SPECT Imaging -- PET Imaging of Microglia Activation in Neuropsychiatric Disorders with Potential Infectious Origin -- PET Imaging in Multiple Sclerosis: Focus on the Translocator Protein -- PET and SPECT Imaging of Neurotoxicity -- PET and SPECT in Hepatic and Uraemic Encephalopathy -- PET in Epilepsy -- SISCOM (Subtraction Ictal SPECT Coregistered to MRI) -- Nuclear Medicine Neuroimaging and Electromagnetic Source Localization in Nonlesional Drug-Resistant Focal Epilepsy -- Gliomas -- Single-Photon Emission Computed Tomography [Neuro-SPECT] Imaging of Brain Tumors -- The Value of ¹¹C-Methionine PET in the Differential Diagnosis Between Brain Tumor Recurrence and Radionecrosis -- Imaging Brain Metastases of Neuroendocrine Tumors -- Traumatic Brain Injury: Nuclear Medicine Neuroimaging -- Whiplash, Real or Not Real? A Review and New Concept -- PET Imaging in Altered States of Consciousness: Coma, Sleep, and Hypnosis -- Anaesthesia and PET of the Brain -- Modulation of Brain Functioning by Deep Brain Stimulation: Contributions from PET Functional Imaging -- Radionuclide Imaging Studies in Pediatric Neurology.
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e-Book
Location
Online
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PET and SPECT in Neurology

https://libcat.nshealth.ca/en/permalink/provcat46368
Rudi A. J. O. Dierckx, Andreas Otte, Erik F. J. de Vries, Aren van Waarde, Klaus L. Leenders, editors. (Second edition) --Cham: Springer , c2021.
Available Online
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This book provides a comprehensive overview of the use of PET and SPECT in not only classic neurodegenerative disorders but also cerebrovascular disorders, brain tumors, epilepsy, head trauma, coma, sleeping disorders, and inflammatory and infectious diseases of the CNS. The new edition has been revised and updated to reflect recent advances and includes additional chapters, for example on the use of artificial intelligence and machine learning in imaging data analysis, the study of brain conne…
Available Online
View e-Book
Other Authors
Dierckx, Rudi A. J. O.
Otte, Andreas
de Vries, Erik F. J.
van Waarde, Aren
Leenders, Klaus L.
Responsibility
Rudi A. J. O. Dierckx, Andreas Otte, Erik F. J. de Vries, Aren van Waarde, Klaus L. Leenders, editors
Edition
Second edition
Place of Publication
Cham
Publisher
Springer
Date of Publication
c2021
Physical Description
1 online resource (xiii, 1289 p.) : 190 illus., 150 illus. in color
ISBN
9783030531683
9783030531676 (Print ed.)
9783030531690 (Print ed.)
9783030531706 (Print ed.)
Subjects (MeSH)
Nervous System Diseases - diagnostic imaging
Neuroimaging - methods
Positron-Emission Tomography
Tomography, Emission-Computed, Single-Photon
Specialty
Diagnostic Imaging
Neurology
Abstract
This book provides a comprehensive overview of the use of PET and SPECT in not only classic neurodegenerative disorders but also cerebrovascular disorders, brain tumors, epilepsy, head trauma, coma, sleeping disorders, and inflammatory and infectious diseases of the CNS. The new edition has been revised and updated to reflect recent advances and includes additional chapters, for example on the use of artificial intelligence and machine learning in imaging data analysis, the study of brain connectivity using PET and SPECT images, and the role of PET imaging in modulation of brain functioning by deep brain stimulation. The authors are renowned experts whose dedication to the investigation of neurological disorders through nuclear medicine technology has achieved international recognition. Most chapters are written jointly by a clinical neurologist and a nuclear medicine specialist to ensure a multidisciplinary approach. This state of the art compendium will be invaluable for neurologists and radiologists/nuclear medicine specialists and will also be informative for interested general practitioners and geriatricians. Companion volumes on PET and SPECT in psychiatry and in neurobiological systems complete a trilogy.
Contents
Part I. Basics -- 1. Nuclear Medicine Imaging Tracers for Neurology -- 2. Tracer Kinetic Modelling -- 3. Quantification in Brain SPECT: Noninvasive Cerebral Blood Flow Measurements Using 99mTc-Labeled Tracers -- 4. From Positron to Pattern: A Conceptual and Practical Overview of 18F-FDG PET Imaging and Spatial Covariance Analysis -- 5. Artificial Intelligence in the Analysis of PET Scans of the Human Brain -- 6. MRI/PET Brain Imaging -- 7. The Default Network of the Brain -- 8. Use of Nuclear Medicine Molecular Neuroimaging to Model Brain Molecular Connectivity -- Part II. Dementia -- 9. PET Neuroimaging in Dementia Conditions 10. Aß Imaging in Aging, Alzheimer’s Disease, and Other Neurodegenerative Conditions -- 11. PET Imaging of the a4ß2* Nicotinic Acetylcholine Receptors in Alzheimer’s Disease -- 12. Neuroimaging Findings in Mild Cognitive Impairment -- 13. Impact of the New Conceptual Framework of Alzheimer’s Disease in Imaging Studies -- 14. Perfusion SPECT: Its Role in the Diagnosis and Differential Diagnosis of Alzheimer’s Disease, with Particular Emphasis on Guidelines -- 15. Nuclear Imaging in Frontotemporal Dementia -- 16. Parkinsonian Dementias: PET Findings -- 17. SPECT/PET Findings in Dementia with Lewy Bodies -- 18. SPECT and PET in Vascular Dementia -- 19. Value of MIBG in the Differential Diagnosis of Neurodegenerative Disorders -- Part III. Cerebrovascular Disorders -- 20. Perfusion Imaging in Healthy Human Aging -- 21. Carotid Plaque Imaging with SPECT/CT and PET/CT -- 22. PET in Brain Arteriovenous Malformations and Cerebral Proliferative Angiopathy -- 23. PET Reveals Pathophysiology in Ischemic Stroke -- Part IV. Movement Disorders -- 24. Parkinson’s Disease -- 25. Computer-Aided Diagnosis of Parkinson’s Disease, Based on SPECT Scans of the Dopamine Transporter -- 26. PET and SPECT Imaging in Atypical Parkinsonian Syndromes -- 27. Amyotrophic Lateral Sclerosis -- 28. PET in Huntington’s Disease -- 29. PET and SPECT Imaging in Dystonia -- 30. PET and SPECT Imaging in Hyperkinetic Movement Disorders -- 31. Clinical Applications of [123I]FP-CIT SPECT Imaging -- Part V. Inflammatory Disorders -- 32. PET Imaging of Microglia Activation and Infection in Neuropsychiatric Disorders with Potential Infectious Origin -- 33. PET Imaging in Multiple Sclerosis -- 34. PET and SPECT Imaging of Neurotoxicity -- 35. PET and SPECT in Hepatic and Uraemic Encephalopathy -- Part VI. Epilepsy -- 36. PET in Epilepsy -- 37. Imaging Evaluation of Epilepsy: Functional and Structural Approaches -- 38. SISCOM (Subtraction Ictal SPECT with Coregistration to MRI) -- Part VII. Tumors of the Nervous System -- 39. Gliomas -- 40. Single-Photon Emission Computed Tomography [Neuro-SPECT] Imaging of Brain Tumors -- 41. The Value of Positron Emission Tomography for Differentiating Brain Tumor Progression and Treatment-Induced Changes -- 42. Imaging Brain Metastases of Neuroendocrine Tumors -- 43. Traumatic Brain Injury: Nuclear Medicine Neuroimaging -- Part VIII. Other Subjects -- 44. Anaesthesia and PET of the Brain -- 45. PET Imaging in Altered States of Consciousness: Coma, Sleep, and Hypnosis -- 46. Modulation of CNS Functions by Deep Brain Stimulation: Insights Provided by Molecular Imaging -- 47. Radionuclide Imaging Studies in Pediatric Neurology.
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PET and SPECT in psychiatry

https://libcat.nshealth.ca/en/permalink/provcat33588
Rudi A.J.O. Dierckx, Andreas Otte, Erik F.J. de Vries, Aren van Waarde, editors ; Johan A. den Boer, guest editor. --Heidelberg: Springer , c2014.
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PET and SPECT in Psychiatry showcases the combined expertise of renowned authors whose dedication to the investigation of psychiatric disease through nuclear medicine technology has achieved international recognition. The classical psychiatric disorders as well as other subjects {u2013} such as suicide, sleep, eating disorders, and autism {u2013} are discussed and the latest results in functional neuroimaging are detailed. Most chapters are written jointly by a clinical psychiatrist and a nucle…
Available Online
View e-Book
Other Authors
Dierckx, Rudi A. J. O
Otte, Andreas P
Vries, Erik F.J. de
Waarde, Aren van
Boer, Johan A. den
Responsibility
Rudi A.J.O. Dierckx, Andreas Otte, Erik F.J. de Vries, Aren van Waarde, editors ; Johan A. den Boer, guest editor
Place of Publication
Heidelberg
Publisher
Springer
Date of Publication
c2014
Physical Description
1 online resource (xxi, 849 pages)
ISBN
9783642403842 (electronic bk.)
9783642403835
Subjects (MeSH)
Mental Disorders - diagnostic imaging
Neuroimaging
Positron-Emission Tomography
Radionuclide Imaging
Tomography, Emission-Computed, Single-Photon
Subjects (LCSH)
Psychiatry - Research
Tomography, Emission - Research
Single-photon emission computed tomography - Research
Abstract
PET and SPECT in Psychiatry showcases the combined expertise of renowned authors whose dedication to the investigation of psychiatric disease through nuclear medicine technology has achieved international recognition. The classical psychiatric disorders as well as other subjects {u2013} such as suicide, sleep, eating disorders, and autism {u2013} are discussed and the latest results in functional neuroimaging are detailed. Most chapters are written jointly by a clinical psychiatrist and a nuclear medicine expert to ensure a multidisciplinary approach. This state of the art compendium will be valuable to all who have an interest in the field of neuroscience, from the psychiatrist and the radiologist/nuclear medicine specialist to the interested general practitioner and cognitive psychologist. It is the first volume of a trilogy on PET and SPECT imaging in the neurosciences; other volumes will focus on PET and SPECT in neurology and PET and SPECT of neurobiological systems.
Contents
Neuroimaging in Psychiatric Drug Development -- Radioligand Development for New Targets -- PET Quantification in Neuropsychiatry -- Pharmacological Interventions that have the Potential to alter Neurotransmitter Levels in the Human Brain -- The Role of P-glycoprotein in Psychiatric Disorders and in Psychiatric Treatment -- Molecular Imaging of Depressive Disorders -- Functional Brain Imaging of Suicidal Behaviour -- Late-Onset Depression -- Neuroimaging in Seasons and Winter Depression -- Bipolar Disorders -- PET and SPECT in Psychiatric Complications of Parkinson's Disease -- Psychiatric Disorders in Dementia -- Imaging of the Antidepressant Drug Response Using SPECT and PET -- Neurotransmission: A Review of PET and SPECT Studies in Anxiety Disorders -- Neurobiology of Posttraumatic Stress Disorder: The Role of Nuclear Neuroimaging -- Neuroimaging in PTSD-related Psychotherapies -- Dissociative Identity Disorder and Fantasy Proneness: A Positron Emission Tomography Study of Authentic and Enacted Dissociative Identity States -- Serotonergic Mechanisms in Obsessive-Compulsive Disorder -- Molecular Imaging in Schizophrenia -- Neuroimaging of Delirium -- PET and SPECT Findings in Patients with Hallucinations -- PET and SPECT in Personality Disorders -- Molecular Imaging Studies in Stimulant Addiction: a Cross-Species Perspective -- Abnormalities in Reward Processing in Drug Addiction: Lessons from Neuropsychology and Neuroimaging Studies -- PET and SPECT Findings in Eating Disorders -- Impulsivity Imaging -- Brain SPECT in the Impulsive-Aggressive Dog -- Obesity an Addiction? Imaging of Neurotransmitter Systems in Obesity -- Neuroimaging Studies of Psychopathy -- Neurobiology of Aggression -- Neuroimaging Findings -- Application of PET and SPECT to the Study of Autism Spectrum Disorders -- PET and SPECT Imaging in Attention Deficit Hyperactivity Disorder -- SPECT and PET Imaging of Apathy -- PET and SPECT Studies in the Chronic Fatigue Syndrome/Myalgic Encephalomyelitis -- Sleep Disorders -- PET and SPECT Imaging of Non-Pharmacological Interventions for Psychiatric Disorders.
Format
e-Book
Location
Online
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PET and SPECT of neurobiological systems

https://libcat.nshealth.ca/en/permalink/provcat33563
Rudi A.J.O. Dierckx, Andreas Otte, Erik F.J. de Vries, Aren van Waarde, editors ; Paul G.M. Luiten, guest editor. --Heidelberg: Springer , c2014.
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Location
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PET and SPECT of Neurobiological Systems combines the expertise of renowned authors whose dedication to the development of novel probes and techniques for the investigation of neurobiological systems has achieved international recognition. Various aspects of neurotransmission in the brain are discussed, such as visualization and quantification of (more than 20 different) neuroreceptors, neuroinflammatory markers, transporters, and enzymes as well as neurotransmitter synthesis, -amyloid depositi…
Available Online
View e-Book
Other Authors
Dierckx, Rudi A. J. O
Otte, Andreas P
Vries, Erik FJ de
Waarde, Aren van
Luiten, Paul G. M
Responsibility
Rudi A.J.O. Dierckx, Andreas Otte, Erik F.J. de Vries, Aren van Waarde, editors ; Paul G.M. Luiten, guest editor
Place of Publication
Heidelberg
Publisher
Springer
Date of Publication
c2014
Physical Description
1 online resource (xviii, 818 pages)
ISBN
9783642420146 (electronic bk.)
9783642420139
Subjects (MeSH)
Neurobiology - methods
Neuroimaging
Positron-Emission Tomography
Tomography, Emission-Computed, Single-Photon
Subjects (LCSH)
Tomography, Emission
Nuclear Medicine
Neurology
Abstract
PET and SPECT of Neurobiological Systems combines the expertise of renowned authors whose dedication to the development of novel probes and techniques for the investigation of neurobiological systems has achieved international recognition. Various aspects of neurotransmission in the brain are discussed, such as visualization and quantification of (more than 20 different) neuroreceptors, neuroinflammatory markers, transporters, and enzymes as well as neurotransmitter synthesis, -amyloid deposition, cerebral blood flow, and the metabolic rate of glucose. The latest results in probe development are also detailed. Most chapters are written jointly by radiochemists and nuclear medicine specialists to ensure a multidisciplinary approach. This state of the art compendium will be valuable to anyone in the field of clinical or preclinical neuroscience, from the radiochemist and radiologist/nuclear medicine specialist to the interested neurobiologist and general practitioner. It is the second volume of a trilogy on PET and SPECT imaging in the neurosciences. Other volumes focus on PET and SPECT in psychiatry and PET and SPECT in neurology.
Contents
BASICS: Animal Models for Brain Research -- Cerebral Glucose Metabolism -- Cerebral Blood Flow Measurements with Oxygen-15 Water PET -- Principles of Brain Perfusion SPECT -- The Impact of Genetic Polymorphisms on Neuroreceptor Imaging -- SYSTEMS: Imaging of Adenosine Receptors -- PET Tracers for Beta-Amyloid and Other Proteinopathies -- Imaging of Central Benzodiazepine Receptors in Chronic Cerebral Ischemia -- PET and SPECT Imaging of the Central Dopamine System in Humans -- PET Imaging of Endocannabinoid System -- Imaging Type 1 Glycine Transporters in the Central Nervous System Using PET -- Imaging Histamine Receptors Using PET and SPECT -- PET and SPECT Imaging of Brain Steroid Hormone Receptors -- Current Radioligands for the PET Imaging of Metabotropic Glutamate Receptors -- PET Imaging of Muscarinic Receptors -- Preclinical Aspects of Nicotinic Acetylcholine Receptor Imaging -- Development of Radioligands for In Vivo Imaging of NMDA Receptors -- Progress in PET Imaging of the Norepinephrine Transporter System -- PET Imaging of Opioid Receptors -- PET Imaging of ABC Transporters in the Blood-Brain Barrier -- PET Imaging of Translocator Protein Expression in Neurological Disorders -- Imaging of the Serotonin System: Radiotracers and Applications in Memory Disorders -- Serotonin Synthesis Studied with PET -- Monoamine Oxidase A and Serotonin Transporter Imaging with PET -- PET Imaging of Sigma-1 Receptors -- Radioligands for Imaging Vesicular Monoamine Transporters.
Format
e-Book
Location
Online
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PET and SPECT of Neurobiological Systems

https://libcat.nshealth.ca/en/permalink/provcat46365
Rudi A.J.O. Dierckx, Andreas Otte, Erik F.J. de Vries, Aren van Waarde, editors ; Adriaan A. Lammertsma, guest editor. (Second edition) --Cham: Springer , c2021.
Available Online
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Access
NEW Springer 2021
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This book, now in a fully updated second edition, is a comprehensive and up-to-date guide to the use of PET and SPECT for the imaging of neurobiological systems. Diverse aspects of neurotransmission in the brain are discussed, such as visualization and quantification of neuroreceptors, neuroinflammatory markers, transporters, and enzymes as well as neurotransmitter synthesis, ß-amyloid deposition, cerebral blood flow, and the metabolic rate of glucose. The latest results in probe development ar…
Available Online
View e-Book
Other Authors
Dierckx, Rudi A.J.O.
Otte, Andreas
de Vries, Erik F.J.
van Waarde, Aren
Lammertsma, Adriaan A.
Responsibility
Rudi A.J.O. Dierckx, Andreas Otte, Erik F.J. de Vries, Aren van Waarde, editors ; Adriaan A. Lammertsma, guest editor
Edition
Second edition
Place of Publication
Cham
Publisher
Springer
Date of Publication
c2021
Physical Description
1 online resource (xii, 1132 p.) : 374 illus., 165 illus. in color
ISBN
9783030531768
9783030531751 (Print ed.)
9783030531775 (Print ed.)
9783030531782 (Print ed.)
Subjects (MeSH)
Neurobiology - methods
Positron-Emission Tomography
Tomography, Emission-Computed, Single-Photon
Specialty
Diagnostic Imaging
Neurology
Physiology
Abstract
This book, now in a fully updated second edition, is a comprehensive and up-to-date guide to the use of PET and SPECT for the imaging of neurobiological systems. Diverse aspects of neurotransmission in the brain are discussed, such as visualization and quantification of neuroreceptors, neuroinflammatory markers, transporters, and enzymes as well as neurotransmitter synthesis, ß-amyloid deposition, cerebral blood flow, and the metabolic rate of glucose. The latest results in probe development are also detailed. A wide range of systems not addressed in the first edition are covered, reflecting the advances made in recent years. The book combines the expertise of authors internationally renowned for their dedication to the development of novel probes and techniques for the investigation of neurobiological systems. Most chapters are written jointly by radiochemists and nuclear medicine specialists to ensure a multidisciplinary approach. This state of the art compendium will be valuable to all with an interest in clinical and preclinical neuroscience. Companion volumes on the use of PET and SPECT in neurology and psychiatry complete a trilogy.
Contents
Part I. Basics -- 1. Animal Models for Brain Research -- 2. The Use of Small Animal Molecular Imaging (µPET) Exemplified in a Neurobiological Pathology -- 3. Total-Body PET -- 4. Cerebral Glucose Metabolism -- 5. Cerebral Blood Flow Measurement with Oxygen-15 Water Positron Emission Tomography -- 6. The Impact of Genetic Polymorphisms on Neuroreceptor Binding: Results from PET and SPECT Neuroreceptor Imaging Studies -- Part II. Systems -- 7. PET Imaging of Acetylcholinesterase -- 8. Imaging of Adenosine Receptors -- 9. Imaging of Central Benzodiazepine Receptors in Chronic Cerebral Ischemia -- 10. PET Imaging of Cyclooxygenases in Neuroinflammation -- 11. PET and SPECT Imaging of the Central Dopamine System in Humans -- 12. PET Imaging of the Endocannabinoid System -- 13. Current Radioligands for the PET Imaging of Metabotropic Glutamate Receptors -- 14. PET and SPECT Imaging of Steroid Hormone Receptors in the Brain -- 15. PET Imaging of Monoamine Oxidase B -- 16. Attempts to Image MRP1 Function in the Blood-Brain Barrier Using the Metabolite Extrusion Method - 17. Neuroinflammation: From Target Selection to Preclinical and Clinical Studies -- 18. Preclinical and Clinical Aspects of Nicotinic Acetylcholine Receptor Imaging -- 19. Development of PET and SPECT Radioligands for In Vivo Imaging of NMDA Receptors -- 20. Progress in PET Imaging of the Norepinephrine Transporter System -- 21. Positron Emission Tomography (PET) Imaging of Opioid Receptors -- 22. PET Imaging of ABC Transporters at the Blood-Brain Barrier -- 23. PET Imaging of Phosphodiesterases in Brain -- 24. PET Imaging of Purinergic Receptors -- 25. Imaging of the Serotonin System: Radiotracers and Applications in Memory Disorders -- 26. Monoamine Oxidase A and Serotonin Transporter Imaging with Positron Emission Tomography -- 27. PET Imaging of Sigma1 Receptors -- 28. Sigma-2 Receptors: An Emerging Target for CNS PET Imaging Studies -- 29. PET Imaging of Synaptic Vesicle Protein 2A -- 30. PET Imaging of Translocator Protein Expression in Neurological Disorders -- 31. Toward Imaging Tropomyosin Receptor Kinase (Trk) with Positron Emission Tomography -- 32. Radioligand Development for PET Imaging of the Vesicular Acetylcholine Transporter (VAChT) in the Brain -- 33. PET Imaging of Vesicular Monoamine Transporters.
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PET-CT : A Case-Based Approach

https://libcat.nshealth.ca/en/permalink/provcat39676
Peter S. Conti, Aarti Kaushik, editors. (Second edition) --New York, NY: Springer , c2016.
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Location
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This book presents original case studies performed on dedicated PET-CT devices and showcasesácommon and uncommon cancers and the latest PET-CT applications for neurological, pediatric, and cardiovascular disorders. This authoritative book, now in its Second Edition, presents correlative three-dimensional cross-sectional PET and CT images that highlight pathological findings. Each case example is accompanied by a concise explanation of the patient history and interpretation of the PET-CT study. …
Available Online
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Other Authors
Conti, Peter S
Kaushik, Aarti
Responsibility
Peter S. Conti, Aarti Kaushik, editors
Edition
Second edition
Place of Publication
New York, NY
Publisher
Springer
Date of Publication
c2016
Physical Description
1 online resource (xiv, 322 p. : 178 illus., 164 illus. in color)
ISBN
9781441958112
9781441958105 (print ed.)
Subjects (MeSH)
Neoplasms - diagnosis
Neoplasms - pathology
Positron-Emission Tomography
Abstract
This book presents original case studies performed on dedicated PET-CT devices and showcasesácommon and uncommon cancers and the latest PET-CT applications for neurological, pediatric, and cardiovascular disorders. This authoritative book, now in its Second Edition, presents correlative three-dimensional cross-sectional PET and CT images that highlight pathological findings. Each case example is accompanied by a concise explanation of the patient history and interpretation of the PET-CT study. "Pearls and pitfalls" and insightful discussions are included to assist in the understanding of pathology, diagnosis, and imaging approaches. The book also discusses pathophysiology and technical artifacts and summarizes the advantages and limitations of using this technology in the clinical setting. PET-CT: A Case-Based Approach, Second Edition, is a valuable resource for nuclear medicine practitioners, radiologists, and residents, as well as referring clinicians interested in learning more about how this imaging modality can be applied in their patient populations. Peter S. Conti is a Professor of Radiology and the Director of the PET Imaging Science Center at the University of Southern California, and is a Fellow of both the American College of Radiology and American College of Nuclear Physicians. He is a pioneer in the development of the clinical applications of PET and PET-CT.
Contents
Normal Patterns and Variants -- Lung Neoplasms -- Breast Neoplasms -- Esophageal and Gastric Neoplasms -- Hepatobiliary, Pancreas, Adrenal, Melanoma, and GIST -- Colon Neoplasms -- Gynecologic Neoplasms: Cervical, Ovarian, Vulvar, Uterine, and Endometrial Cancer -- Urologic Neoplasms: Prostate, Bladder, and Renal Cell Carcinoma -- Lymphoma -- Musculoskeletal Neoplasms -- F-18 Fluoride Bone Scintigraphy -- Neuroradiology: Neoplasms and Epilepsy -- Dementia -- Pediatric Imaging -- Myocardial Viability -- Granulomatous Diseases -- Newer Tracers.
Format
e-Book
Publication Type
Case Reports
Location
Online
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PET-CT and PET-MRI in Neurology : SWOT Analysis Applied to Hybrid Imaging

https://libcat.nshealth.ca/en/permalink/provcat40206
Andrea Ciarmiello, Luigi Mansi, editors. --Cham: Springer , c2016.
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Using SWOT analysis, this book examines in detail the strengths and weaknesses of the hybrid modalities PET-CT and PET-MRI for imaging of the central nervous system, comparing their merits and evaluating their advantages over the stand-alone modalities. The aim is to employ a truly systematic approach in order to define the potential clinical benefit of these modalities and to identify shortcomings, opportunities, and threats. Clinical application of the modalities is explored in a range of con…
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Other Authors
Ciarmiello, Andrea
Mansi, Luigi
Responsibility
Andrea Ciarmiello, Luigi Mansi, editors
Place of Publication
Cham
Publisher
Springer
Date of Publication
c2016
Physical Description
1 online resource (x, 319 p. : 79 illus., 71 illus. in color)
ISBN
9783319316147
9783319316123 (print ed.)
Subjects (MeSH)
Evaluation Studies as Topic
Magnetic Resonance Imaging
Multimodal Imaging
Neuroimaging
Positron-Emission Tomography
Tomography, X-Ray Computed
Abstract
Using SWOT analysis, this book examines in detail the strengths and weaknesses of the hybrid modalities PET-CT and PET-MRI for imaging of the central nervous system, comparing their merits and evaluating their advantages over the stand-alone modalities. The aim is to employ a truly systematic approach in order to define the potential clinical benefit of these modalities and to identify shortcomings, opportunities, and threats. Clinical application of the modalities is explored in a range of conditions, including dementia and related disorders, movement disorders, psychiatric disorders, cerebrovascular disease, infection/inflammation, brain tumors, and pediatric neurologic disorders. In addition, the basics of hybrid imaging are addressed, covering physics, instrumentation, data analysis and quantitation, radiopharmaceuticals, and contrast media. PET-CT and PET-MRI in Neurology, written by experts from Europe and the United States, will be essential reading for imaging specialists and of value for neurologists, psychiatrists, neurosurgeons, and pediatricians.
Contents
Part I. Basics -- Physics Of Hybrid Imaging -- Instrumentation -- Quantitation And Data Analysis In Hybrid PET/MRI Systems -- Radiopharmaceuticals -- Contrast Media -- Part II. Most Frequent Clinical Applications -- FDG-PET in Dementia -- Amyloid imaging in dementia and related disorders -- Movement disorders: focus on Parkinson's disease and related disorders -- Psychiatric disorders -- PET/CT and PET/MRI in Neurology: Infection/Inflammation -- Brain Tumors -- Hybrid Imaging in Pediatric Central Nervous System Disorders -- Part III. Less Frequent Clinical Applications -- Multimodality Imaging of Huntington's Disease -- Neuroimaging in Amyotrophic Lateral Sclerosis -- Hybrid imaging in vegetative state -- Hybrid imaging in cerebrovascular disease -- Hybrid imaging in Emergency Room -- Part IV. SWOT analysis -- SWOT Analysis and Stakeholder Engagement for Comparative Evaluation of Hybrid Molecular Imaging Modalities -- Worldwide Challenges and Opportunities of Hybrid Imaging: Perspective from the International Atomic Energy Agency (IAEA) -- PET/CT vs PET/MRI.
Format
e-Book
Location
Online
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PET/CT for Inflammatory Diseases : Basic Sciences, Typical Cases, and Review

https://libcat.nshealth.ca/en/permalink/provcat44803
Hiroshi Toyama, Yaming Li, Jun Hatazawa, Guang Huang, Kazuo Kubota, editors. --Singapore: Springer , c2020.
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Location
Online
This comprehensive guide sheds new light on the benefits of FDG PET/CT in diagnosing inflammatory diseases. Although FDG PET/CT offers an invaluable tool for diagnosing inflammatory diseases, the clinical evidence on its application remains limited. To remedy this gap, each chapter of this book includes detailed descriptions of how FDG PET/CT can be used in connection with a specific inflammatory disease. Further, the authors discusses the precise clinical presentation, including key images and…
Available Online
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Other Authors
Toyama, Hiroshi
Li, Yaming
Hatazawa, Jun
Huang, Guang
Kubota, Kazuo
Responsibility
Hiroshi Toyama, Yaming Li, Jun Hatazawa, Guang Huang, Kazuo Kubota, editors
Place of Publication
Singapore
Publisher
Springer
Date of Publication
c2020
Physical Description
1 online resource (xvii, 233 p.) : 179 illus., 146 illus. in color
ISBN
9789811508103
9789811508097 (Print ed.)
9789811508110 (Print ed.)
9789811508127 (Print ed.)
Subjects (MeSH)
Fluorodeoxyglucose F18
Inflammation - diagnostic imaging
Positron-Emission Tomography
Tomography, X-Ray Computed
Specialty
Diagnostic Imaging
Pathology
Abstract
This comprehensive guide sheds new light on the benefits of FDG PET/CT in diagnosing inflammatory diseases. Although FDG PET/CT offers an invaluable tool for diagnosing inflammatory diseases, the clinical evidence on its application remains limited. To remedy this gap, each chapter of this book includes detailed descriptions of how FDG PET/CT can be used in connection with a specific inflammatory disease. Further, the authors discusses the precise clinical presentation, including key images andtheir interpretation, techniques and diagnosis. As such, it allows readers to see for themselves how valuable FDG PET/CT is for the diagnosis of cardiac sarcoidosis and aortitis syndrome, as well as rheumatic diseases and neuroimflammation, and the detection of the disease focus of inflammation or fever of unknown origin. Given its scope, this excellent collection is a valuable resource for radiologists and physicians who are involved in nuclear medicine, as well as cardiologists, cardiovascular surgeons, and rheumatologists.
Contents
1. Basic Science of PET Imaging for Inflammatory Diseases -- 2. FDG PET/CT in Patients with Inflammation or Fever of Unknown Origin (IUO & FUO) -- 3. FDG-PET/CT for a Variety of Infectious Diseases -- 4. Hematological Diseases Mimic Inflammation -- 5. FDG-PET/CT for Large-Vessel Vasculitis -- 6. FDG PET/CT for Rheumatic Diseases (Collagen Diseases) -- 7. FDG PET/CT for Sarcoidosis -- 8. PET/CT for Neuroinflammation.
Format
e-Book
Location
Online
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PET/CT in Hodgkin's Lymphoma

https://libcat.nshealth.ca/en/permalink/provcat41816
Irfan Kayani, editor. --Cham: Springer , 2017.
Available Online
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Location
Online
This book is a pocket guide to the practice of PET/CT imaging of Hodgkin's lymphoma. The role of PET/CT in Hodgkin's lymphoma, the characteristic findings and patterns, and the advantages and limitations of this hybrid modality are all clearly described. In addition, information is provided on clinical presentation, diagnosis, staging, pathology, management, and conventional radiological imaging. A useful pictorial atlas is included at the end of the book. PET/CT in Hodgkin's Lymphoma is publis…
Available Online
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Other Authors
Kayani, Irfan
Responsibility
Irfan Kayani, editor
Place of Publication
Cham
Publisher
Springer
Date of Publication
2017
Physical Description
1 online resource (xv, 93 pages) : 41 illus., 36 illus. in color
Series Title
CliniciansÇÖ Guides to Radionuclide Hybrid Imaging
ISBN
9783319572253
9783319572246 (print ed.)
Subjects (MeSH)
Lymphoma - diagnosis
Lymphoma - therapy
Positron-Emission Tomography
Tomography, X-Ray Computed
Hodgkin Disease
Abstract
This book is a pocket guide to the practice of PET/CT imaging of Hodgkin's lymphoma. The role of PET/CT in Hodgkin's lymphoma, the characteristic findings and patterns, and the advantages and limitations of this hybrid modality are all clearly described. In addition, information is provided on clinical presentation, diagnosis, staging, pathology, management, and conventional radiological imaging. A useful pictorial atlas is included at the end of the book. PET/CT in Hodgkin's Lymphoma is published within the Springer series Clinicians' Guides to Radionuclide Hybrid Imaging, which is aimed at referring clinicians, nuclear medicine/radiology physicians, radiographers/technologists, and nurses who routinely work in nuclear medicine and participate in multidisciplinary meetings. Compiled under the auspices of the British Nuclear Medicine Society, the series is the joint work of many colleagues and professionals worldwide who share a common vision and purpose in promoting and supporting nuclear medicine as an important imaging specialty for the diagnosis and management of oncological and non-oncological conditions.
Contents
1. Hodgkin Lymphoma -- 2. Pathology of Hodgkin Lymphoma -- 3. Management of Hodgkin Lymphoma -- 4. Radiological imaging in Lymphoma -- 5. PET in Hodgkin's Lymphoma -- 6. 18F FDG PET-CT: Normal Variants, Artefacts and Pitfalls in Lymphoma -- 7. PET/CT in Hodgkin Lymphoma: Teaching Cases.
Format
e-Book
Location
Online
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