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3-D conformal and intensity modulated radiation therapy : physics and clinical applications

https://libcat.nshealth.ca/en/permalink/provcat21050
Purdy, James A. --Madison, WI: Advanced Medical Publishing , 2001.
Call Number
WN 250 P985t 2001
Location
Dickson Building
Call Number
WN 250 P985t 2001
Author
Purdy, James A
Place of Publication
Madison, WI
Publisher
Advanced Medical Publishing
Date of Publication
2001
Physical Description
612 p.
ISBN
1883526108
Subjects (MeSH)
Radiotherapy
Format
Book
Location
Dickson Building
Loan Period
3 weeks
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Absolute Clinical Radiation Oncology Review

https://libcat.nshealth.ca/en/permalink/provcat44248
Daniel M. Trifiletti, Nicholas G. Zaorsky, editors. --Cham: Springer , 2019.
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Location
Online
This book provides a quick reference guide for clinicians in radiation oncology. It is designed to be an intuitive and easily reviewed study guide for board or maintenance of certification examinations, as well as a quick reference for residents and established radiation oncologists who need a refresher. The text begins with a general pearls chapter that radiation oncologists should consider in all aspects of their practice, including cancer visibility, dosing, counseling recommendations, and t…
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Other Authors
Trifiletti, Daniel M.
Zaorsky, Nicholas G.
Responsibility
Daniel M. Trifiletti, Nicholas G. Zaorsky, editors
Place of Publication
Cham
Publisher
Springer
Date of Publication
2019
Physical Description
1 online resource (xvii, 492 p.) : 191 illus., 178 illus. in color
ISBN
9783319968094
9783319968087 (Print ed.)
9783319968100 (Print ed.)
Subjects (MeSH)
Neoplasms - radiotherapy
Radiation Oncology
Specialty
Medical Oncology
Radiotherapy
Abstract
This book provides a quick reference guide for clinicians in radiation oncology. It is designed to be an intuitive and easily reviewed study guide for board or maintenance of certification examinations, as well as a quick reference for residents and established radiation oncologists who need a refresher. The text begins with a general pearls chapter that radiation oncologists should consider in all aspects of their practice, including cancer visibility, dosing, counseling recommendations, and toxicity management. The subsequent chapters then delve into different cancer disease sites, including pediatrics, central nervous system, head and neck, thoracic, breast, gastrointestinal, gynecologic, genitourinary, hematologic, soft tissue, palliative, and radiophysics/radiobiology. Within each chapter, each disease and its recommended approach is then summarized in only a few pages, allowing a focus on the most essential information. Bullet points, figures, tables, and images make for an intuitive reader experience. The text includes the 7th and 8th editions staging from the American Joint Committee on Cancer (AJCC). Recommendations are taken from the American Society for Radiation Oncology (ASTRO), the European Society for Radiation Oncology (ESTRO), and the National Comprehensive Cancer Network (NCCN). Planning guides for imaging, diagnosis, and staging offer readers a starting point in approaching each patient based on disease origin, and dosing guidelines then detail consideration for treatment methods. Each chapter additionally includes disease-specific pearls and key points to test the knowledge reviewed in the chapters. Experts in the disease sites from the United States serve as senior authors on each chapter. The authors include all diseases associated with radiation oncology training to ensure a comprehensive resource for exam studying and clinical care. Residents, trainees, and established radiation oncologists find this an ideal study resource for both board and certification exams, as well as an easily accessible aid during practice.
Contents
1. General Principles of Radiation Oncology -- 2. Pediatrics Cancers - 3. Central Nervous System Cancers -- 4. Head and Neck Cancers -- 5. Lung Cancer -- 6. Breast Cancer -- 7. Gastrointestinal Cancers -- 8. Genitourinary Cancers -- 9. Gynecologic Cancers -- 10. Hematologic Cancers -- 11. Soft Tissue Cancers -- 12. Bone/Spine Cancers -- 13. Physics and Radiobiology.
Format
e-Book
Publication Type
Outline
Location
Online
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Accelerated Partial Breast Irradiation : Techniques and Clinical Implementation

https://libcat.nshealth.ca/en/permalink/provcat28378
edited by David E. Wazer, Douglas W. Arthur, Frank A. Vicini. (2nd ed.) --Berlin, Heidelberg: Springer , c2009.
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Location
Online
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Author
Wazer, David E
Other Authors
Arthur, Douglas W
Vicini, Frank A
Responsibility
edited by David E. Wazer, Douglas W. Arthur, Frank A. Vicini
Edition
2nd ed.
Place of Publication
Berlin, Heidelberg
Publisher
Springer
Date of Publication
c2009
ISBN
9783540880066
Subjects (MeSH)
Breast Neoplasms - radiotherapy
Radiotherapy, Conformal - methods
Subjects (LCSH)
Radiotherapy
Oncology
Gynecology
Format
e-Book
Location
Online
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Adult CNS Radiation Oncology : Principles and Practice

https://libcat.nshealth.ca/en/permalink/provcat42554
Eric L. Chang, Paul D. Brown, Simon S. Lo, Arjun Sahgal, John H. Suh, editors. --Cham: Springer , c2018.
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Location
Online
This book elucidates the radiation therapy protocols and procedures for the management of adult patients presenting with primary benign and malignant central nervous system tumors. With the development of new treatment strategies and rapid advancement of radiation technology, it is crucial for radiation oncologists to maintain and refine their knowledge and skills. Dedicated exclusively to adult CNS radiation oncology, this textbook explores CNS tumors ranging from the common to the esoteric as…
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Other Authors
Chang, Eric L.
Brown, Paul D.
Lo, Simon S.
Sahgal, Arjun
Suh, John H.
Responsibility
Eric L. Chang, Paul D. Brown, Simon S. Lo, Arjun Sahgal, John H. Suh, editors
Alternate Title
Adult central nervous system radiation oncology
Place of Publication
Cham
Publisher
Springer
Date of Publication
c2018
Physical Description
1 online resource (xxi, 766 p.) : 349 illus., 257 illus. in color
ISBN
9783319428789
9783319428772 (print ed.)
9783319428796 (print ed.)
Subjects (MeSH)
Adult
Central Nervous System Diseases - radiotherapy
Central Nervous System Neoplasms - radiotherapy
Radiation Oncology - methods
Radiotherapy - adverse effects
Specialty
Medical Oncology
Neurology
Radiotherapy
Abstract
This book elucidates the radiation therapy protocols and procedures for the management of adult patients presenting with primary benign and malignant central nervous system tumors. With the development of new treatment strategies and rapid advancement of radiation technology, it is crucial for radiation oncologists to maintain and refine their knowledge and skills. Dedicated exclusively to adult CNS radiation oncology, this textbook explores CNS tumors ranging from the common to the esoteric as well as secondary cancers of metastatic origin. The first half of the book is organized anatomically: tumors of the brain, spinal cord, leptomeninges, optic pathway, ocular choroid, and skull base. The second half covers primary CNS lymphoma, rare CNS tumors, metastatic brain disease, vascular conditions of the CNS, radiation-associated complications, and radiation modalities. Each chapter provides guidance on treatment field design, target delineation, and normal critical structure tolerance constraints in the context of the disease being treated. Learning objectives, case studies, and Maintenance of Certification Self-Assessment Continuing Medical Education-style questions and answers are incorporated throughout the book. This is an ideal guide for radiation oncologists, residents, and fellows, but medical students may also find value in the text.
Contents
Part I. Brain Tumors: Benign -- Meningioma -- Pituitary Adenoma -- Craniopharyngioma -- Vestibular Schwannoma -- Part II. Brain Tumors: Malignant Gliomas -- Low Grade Glioma -- High Grade Gliomas -- Part III. Spine: Benign -- Schwannomas and Neurofibromas -- Spinal Meningioma -- Part IV. Spine: Malignant -- Astrocytic Tumors of Spinal Cord -- Spinal Cord Ependymoma -- Part V. Spine: Metastatic -- Metastatic Epidural Spinal Cord Compression: Conventional Radiotherapy -- Vertebral Body Metastasis -- Part VI. Leptomeningeal Disease -- Evaluation and Workup of Leptomeningeal Disease -- Palliative Radiation Therapy for Leptomeningeal Disease -- Part VII. Optic Pathway Tumors -- Optic Pathway Gliomas -- Optic Nerve Sheath Meningioma -- Part VIII. Ocular Oncology -- Uveal Melanoma -- Part IX. Skull Base Tumor -- Skull Base Tumors -- Part X. Primary Central Nervous System Lymphoma -- Primary Central Nervous System Lymphoma -- Part XI. Rare Tumors -- Choroid Plexus Tumors -- Hemangiopericytoma -- Stereotactic Radiosurgery for Hemangioblastomas -- NF2 Related Tumors and Malignant Peripheral Nerve Sheath Tumors -- Germ Cell Tumors -- Pineal Region Tumors -- Glomus Tumors -- Adult Medulloblastoma -- Intracranial Ependymoma -- Central Neurocytoma -- Part XII. Metastatic Brain Disease -- Prognostic Classification Systems for Brain Metastases -- Neurosurgical Management of Single Brain Metastases -- Multiple Brain Metastases -- Postoperative Treatment for Brain Metastasis -- Part XIII. Vascular Conditions of the CNS -- Vascular Malformation -- Trigeminal Neuralgia -- Part XIV. Radiation Associated Complications -- Brain Radionecrosis -- Spinal Cord Tolerance and Risk of Radiation Myelopathy -- Radiation Optic Neuropathy -- Cerebral Atrophy and Leukoencephalopathy Following Cranial Irradiation -- Hypopituitarism -- Neurocognitive Changes -- Cranial Nerve Palsies, Vascular Damage, and Brainstem Injury -- Part XV. Radiation Modalities Applied to CNS Tumors -- 3-D Conformal Therapy and Intensity Modulated Radiation Therapy/Volumetric Modulated Arc Therapy -- Linac Based Stereotactic Radiosurgery and Hypofractionated Stereotactic Radiotherapy -- Gamma Knife’ Stereotactic Radiosurgery and Hypo-Fractionated Stereototatic Radiotherapy -- Spinal Stereotactic Body Radiotherapy -- Proton Beam Therapy (For CNS Tumors) -- Brachytherapy.
Format
e-Book
Location
Online
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Advances in radiation oncology

https://libcat.nshealth.ca/en/permalink/provcat42117
Elsevier
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Holdings
Vol 1, 2016 -
Location
Online
Available Online
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Publisher
Elsevier
Holdings
Vol 1, 2016 -
ISSN
2452-1094
Specialty
Neoplasms
Radiology
Radiotherapy
Format
e-Journal
Location
Online
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Advances in radiation oncology in lung cancer

https://libcat.nshealth.ca/en/permalink/provcat28993
(2nd ed.) --Berlin, Heidelberg: Springer-Verlag , c2011.
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Location
Online
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Other Authors
Jeremic, Branislav
Edition
2nd ed.
Place of Publication
Berlin, Heidelberg
Publisher
Springer-Verlag
Date of Publication
c2011
Series
Medical radiology. Radiation oncology
Series Title
Medical radiology (Series)
ISBN
9783642199257
Subjects (MeSH)
Lung Neoplasms - radiotherapy
Subjects (LCSH)
Radiotherapy
Pneumology
Oncology
Format
e-Book
Location
Online
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Alternate Fractionation in Radiotherapy : Paradigm Change

https://libcat.nshealth.ca/en/permalink/provcat42545
Mark Trombetta, Jean-Philippe Pignol, Paolo Montemaggi, Luther W. Brady, editors. --Cham: Springer , c2018.
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Location
Online
This book, written by leading international experts, describes alternate fractionation strategies in which technology-driven precise targeting and dosing allow for improved conformance and decreased volumes, with concordant lessening of toxicity, reduction in treatment time, and lower overall health care expense. The aim is to provide the advanced clinician with an up-to-date evidence-based reference that will assist in the delivery of enhanced patient care in daily practice. Traditional multi-…
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Other Authors
Trombetta, Mark
Pignol, Jean-Philippe
Montemaggi, Paolo
Brady, Luther W.
Responsibility
Mark Trombetta, Jean-Philippe Pignol, Paolo Montemaggi, Luther W. Brady, editors
Place of Publication
Cham
Publisher
Springer
Date of Publication
c2018
Physical Description
1 online resource (xii, 413 p.) : 100 illus.
Series
Medical radiology. Radiation oncology
Series Title
Medical radiology (Series)
ISBN
9783319511986
9783319511979 (print ed.)
9783319511993 (print ed.)
9783030095963 (print ed.)
Subjects (MeSH)
Dose Fractionation, Radiation
Neoplasms - radiotherapy
Specialty
Pharmacy
Radiotherapy
Abstract
This book, written by leading international experts, describes alternate fractionation strategies in which technology-driven precise targeting and dosing allow for improved conformance and decreased volumes, with concordant lessening of toxicity, reduction in treatment time, and lower overall health care expense. The aim is to provide the advanced clinician with an up-to-date evidence-based reference that will assist in the delivery of enhanced patient care in daily practice. Traditional multi-week fractionation schedules were established at a time when the inclusion of relatively large amounts of normal tissue was unavoidable owing to the lack of accurate target localization during treatment. Such schedules are time and resource consuming, difficult for patients, and expensive. Nevertheless, acceptance of alternate fractionation strategies has been slow in some countries. The paradigm is, however, changing as evidence accumulates to demonstrate improved local control, equivalence of tolerance, or both. In documenting these alternate strategies, this book will be of value for radiation oncologists, medical physicists, and oncologists worldwide.
Contents
Introduction -- The Radiobiological Aspects of Altered Fractionation -- Technological Advance Enabling Alternate Fractionation -- Workflow and Quality Assurance in Altered Fractionation -- The Future of Altered Fractionation -- Brachytherapy: The Original Altered Fractionation -- Part I. Disease Site Specific Topics -- Altered Fractionation in Radiotherapy of CNS Tumors -- Head and Neck Cancer -- Whole-Breast Hypofractionated Radiotherapy -- Accelerated Partial Breast Irradiation -- Lung Cancer -- Alternate Fractionation for Hepatic Tumors -- Stereotactic Body Radiotherapy with Functional Treatment Planning in Hepatocellular Carcinoma -- Gastrointestinal Cancer: Pancreas -- Hypofractionation in Patients with Rectal Cancer -- Hypofractionated Radiotherapy in Genitourinary Cancer: Better with Less -- Fractionation Regimens for Gynecologic Malignancies -- Skin: The Case for Altered Fractionation in the Treatment of Both Malignant and Benign Conditions -- Radiotherapy for Primary and Metastatic Soft Tissue Sarcomas: Altered Fraction Regimens with External Beam and Brachytherapy -- Stereotactic Body Radiotherapy -- Altered Fraction Radiotherapy in Palliation -- Erratum to: The Radiobiological Aspects of Altered Fractionation.
Format
e-Book
Location
Online
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Basic clinical radiobiology

https://libcat.nshealth.ca/en/permalink/provcat21151
Steel, G. Gordon. (3rd ed.) --London, England: Arnold , 2002.
Call Number
WN 600 S813b 2002
Location
Dickson Building
Call Number
WN 600 S813b 2002
Author
Steel, G. Gordon
Edition
3rd ed.
Place of Publication
London, England
Publisher
Arnold
Date of Publication
2002
Physical Description
262 p.
ISBN
0340807830
Subjects (MeSH)
Radiobiology
Radiotherapy
Format
Book
Location
Dickson Building
Loan Period
3 weeks
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Basic radiotherapy physics and biology

https://libcat.nshealth.ca/en/permalink/provcat33462
David S. Chang, Foster D. Lasley, Indra J. Das, Marc S. Mendonca, Joseph R. Dynlacht. --New York: Springer , c2014.
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Location
Online
This book is a concise and well-illustrated review of the physics and biology of radiation therapy intended for radiation oncology residents, radiation therapists, dosimetrists, and physicists. It presents topics that are included on the Radiation Therapy Physics and Biology examinations and is designed with the intent of presenting information in an easily digestible format with maximum retention in mind. The inclusion of mnemonics, rules of thumb, and reader-friendly illustrations throughout …
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Other Authors
Chang, David S
Responsibility
David S. Chang, Foster D. Lasley, Indra J. Das, Marc S. Mendonca, Joseph R. Dynlacht
Place of Publication
New York
Publisher
Springer
Date of Publication
c2014
Physical Description
1 online resource (xix, 348 pages)
ISBN
9783319068411 (electronic bk.)
9783319068404
Subjects (MeSH)
Health Physics
Radiometry
Radiotherapy
Subjects (LCSH)
Radiotherapy
Diagnostic Radiology
Abstract
This book is a concise and well-illustrated review of the physics and biology of radiation therapy intended for radiation oncology residents, radiation therapists, dosimetrists, and physicists. It presents topics that are included on the Radiation Therapy Physics and Biology examinations and is designed with the intent of presenting information in an easily digestible format with maximum retention in mind. The inclusion of mnemonics, rules of thumb, and reader-friendly illustrations throughout the book help to make difficult concepts easier to grasp. Basic Radiotherapy Physics and Biology is a valuable reference for students and prospective students in every discipline of radiation oncology.
Contents
Part I. Radiation Therapy Physics -- 1. Atomic and Nuclear Structure -- 2. Radioactive Decay -- 3. Production and Properties of Radiation -- 4. Interactions of Electromagnetic Radiation with Matter -- 5. Interactions of Particulate Radiation with Matter -- 6. Quantification and Measurement of Dose -- 7. Characteristics of Photon Beams -- 8. Dosimetry of Photon Beams in Water -- 9. Dosimetry of Photon Beams in a Patient -- 10. Dosimetry of Electron Beams -- 11. Physics and Dosimetry of Brachytherapy -- 12. Advanced Treatment Planning for EBRT -- 13. Linac Quality Assurance -- 14. Radiation Protection and Safety -- 15. Quality Management Program -- 16. Special Topics: Hyperthermia and Computers -- Part II. Radiation Therapy Biology -- 17. Molecular Biology and Signaling -- 18. Cancer Genetic and Molecular Characteristics -- 19. Molecular Mechanisms of DNA Damage and Repair -- 20. Cell Death and Survival Assays -- 21. Fractionated Radiation Survival Models -- 22. Oxygen Effect, Relative Biological Effectiveness and Linear Energy Transfer -- 23. Tumor Micro-environment -- 24. Cell and Tissue Kinetics -- 25. Acute Effects of Total Body Irradiation (TBI) -- 26. Normal Tissue Radiation Responses -- 27. Therapeutic Ratio -- 28. Combined Modality Therapy -- 29. Biology of Brachytherapy, Particle Therapy, and Alternative Radiation Modalities -- 30. Hyperthermia -- 31. Carcinogenesis and Heritable Effects -- 32. Radiation Effects in the Embryo and Fetus -- Appendix A. Glossary of Terms and Physical Constants -- Appendix B. List of Radionuclides for Radiotherapy and Imaging.
Format
e-Book
Location
Online
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Basic Radiotherapy Physics and Biology

https://libcat.nshealth.ca/en/permalink/provcat46594
David S. Chang, Foster D. Lasley, Indra J. Das, Marc S. Mendonca, Joseph R. Dynlacht. (Second edition) Springer , 2021.
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Location
Online
Available Online
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Responsibility
David S. Chang, Foster D. Lasley, Indra J. Das, Marc S. Mendonca, Joseph R. Dynlacht
Edition
Second edition
Publisher
Springer
Date of Publication
2021
Physical Description
1 online resource (xxiii, 380 pages) : illustrations
ISBN
9783030618995
Specialty
Radiotherapy
Format
e-Book
Location
Online
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Basics of Planning and Management of Patients during Radiation Therapy : A Guide for Students and Practitioners

https://libcat.nshealth.ca/en/permalink/provcat43094
Ashutosh Mukherji. --Singapore: Springer , c2018.
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Location
Online
This book summarizes the do's and don'ts of managing a patient receiving radiotherapy as well as how to manage common day to day situations that one comes across in radiation oncology practice. It serves as a useful guide for radiation oncology practitioners for practical exams. This book offers assistance to young radiotherapists in handling cancer patients.
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Author
Mukherji, Ashutosh
Responsibility
Ashutosh Mukherji
Place of Publication
Singapore
Publisher
Springer
Date of Publication
c2018
Physical Description
1 online resource (xvii, 403 p.) : 88 illus., 86 illus. in color
ISBN
9789811066597
9789811066580 (print ed.)
9789811066603 (print ed.)
Subjects (MeSH)
Neoplasms - radiotherapy
Patient Care Planning
Radiotherapy
Treatment Outcome
Specialty
Radiotherapy
Abstract
This book summarizes the do's and don'ts of managing a patient receiving radiotherapy as well as how to manage common day to day situations that one comes across in radiation oncology practice. It serves as a useful guide for radiation oncology practitioners for practical exams. This book offers assistance to young radiotherapists in handling cancer patients.
Contents
Part I. Approaching a Cancer Patient -- 1. Taking a Decision and Ordering Investigations -- 2. Role of Surgery in Cancer Management -- 3. Radiotherapy in Cancer Care -- 4. Role of Chemotherapy in Management of Cancers -- 5. Principles of Management of Cancers in Paediatric Patients -- 6. Palliative and Supportive Care of Cancers -- Part II. Principles of Application of Radiotherapy -- 7. Radiobiological Principles -- 8. Patient’s Positioning and Simulation: Do’s and Don’ts -- 9. Planning a Patient, Deciding on the Volumes and Fields and Plan Verification -- 10. Conformal Radiotherapy: Simulation and Contouring -- 11. Prescribing a Radiotherapy Schedule and Dose Fractionation -- 12. Evaluating a Treatment Plan -- 13. An Introduction to Brachytherapy -- 14. Brachytherapy Planning and Evaluation -- 15. Planning Electron Therapy and Evaluation of Plans -- 16. Planning Stereotactic and Adaptive Radiotherapy -- 17. Intraoperative Radiotherapy -- 18. Particle Beam Therapy: A Quick View -- Part III. Use of Other Agents with Radiation -- 19. Using Concurrent or Sequential Chemotherapy and Biomolecules -- 20. Use of Radiosensitizers and Radioprotectors -- Part IV. Managing Radiotherapy Complications -- 21. Expected Complications During Treatment -- 22. Management of Oral Mucosal Reactions and Oro-dental Care -- 23. Management of Skin Reactions -- 24. Management of GI Complications -- 25. Managing Local Pain -- 26. Managing Bone Marrow Toxicities -- 27. Managing Complications: Lymphoedema and Fibrosis -- 28. Dietary Care and Support During Radiotherapy -- 29. Post-treatment Evaluation and Advice and Follow-Up Schedules -- 30. Psychological and Social Issues in Patients Undergoing Radiotherapy.
Format
e-Book
Location
Online
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Breast Cancer : Nuclear Medicine in Diagnosis and Therapeutic Options

https://libcat.nshealth.ca/en/permalink/provcat28882
edited by Emilio Bombardieri, Luca Gianni, Gianni Bonadonna. --Berlin, Heidelberg: Springer-Verlag , c2008.
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Location
Online
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Author
Bombardieri, Emilio
Other Authors
Gianni, Luca
Bonadonna, Gianni
Responsibility
edited by Emilio Bombardieri, Luca Gianni, Gianni Bonadonna
Place of Publication
Berlin, Heidelberg
Publisher
Springer-Verlag
Date of Publication
c2008
ISBN
9783540367819
Subjects (MeSH)
Breast Neoplasms - diagnosis
Breast Neoplasms - therapy
Nuclear Medicine
Subjects (LCSH)
Gynecology
Oncology
Nuclear medicine
Radiotherapy
Format
e-Book
Location
Online
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Carbon-ion radiotherapy : principles, practices, and treatment planning

https://libcat.nshealth.ca/en/permalink/provcat33771
Hirohiko Tsujii, Tadashi Kamada, Toshiyuki Shirai, Koji Noda, Hiroshi Tsuji, Kumiko Karasawa, editors. --Tokyo: Springer , c2014.
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Location
Online
This book serves as a practical guide for the use of carbon ions in cancer radiotherapy. On the basis of clinical experience with more than 7,000 patients with various types of tumors treated over a period of nearly 20 years at the National Institute of Radiological Sciences, step-by-step procedures and technological development of this modality are highlighted. The book is divided into two sections, the first covering the underlying principles of physics and biology, and the second section is …
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Other Authors
Tsujii, Hirohiko
Responsibility
Hirohiko Tsujii, Tadashi Kamada, Toshiyuki Shirai, Koji Noda, Hiroshi Tsuji, Kumiko Karasawa, editors
Place of Publication
Tokyo
Publisher
Springer
Date of Publication
c2014
Physical Description
1 online resource (xii, 312 pages)
ISBN
9784431544579 (electronic bk.)
9784431544562
Subjects (MeSH)
Heavy Ion Radiotherapy - instrumentation
Heavy Ion Radiotherapy - methods
Subjects (LCSH)
Radiotherapy
Oncology
Medical and Radiation Physics
Abstract
This book serves as a practical guide for the use of carbon ions in cancer radiotherapy. On the basis of clinical experience with more than 7,000 patients with various types of tumors treated over a period of nearly 20 years at the National Institute of Radiological Sciences, step-by-step procedures and technological development of this modality are highlighted. The book is divided into two sections, the first covering the underlying principles of physics and biology, and the second section is a systematic review by tumor site, concentrating on the role of therapeutic techniques and the pitfalls in treatment planning. Readers will learn of the superior outcomes obtained with carbon-ion therapy for various types of tumors in terms of local control and toxicities. It is essential to understand that the carbon-ion beam is like a two-edged sword: unless it is used properly, it can increase the risk of severe injury to critical organs. In early series of dose-escalation studies, some patients experienced serious adverse effects such as skin ulcers, pneumonitis, intestinal ulcers, and bone necrosis, for which salvage surgery or hospitalization was required. To preclude such detrimental results, the adequacy of therapeutic techniques and dose fractionations was carefully examined in each case. In this way, significant improvements in treatment results have been achieved and major toxicities are no longer observed. With that knowledge, experts in relevant fields expand upon techniques for treatment delivery at each anatomical site, covering indications and optimal treatment planning. With its practical focus, this book will benefit radiation oncologists, medical physicists, medical dosimetrists, radiation therapists, and senior nurses whose work involves radiation therapy, as well as medical oncologists and others who are interested in radiation therapy.
Contents
Part I. The history of carbon-ion radiotherapy -- Part II. An overview of carbon-ion radiotherapy -- Part III. Radiobiology of carbon-ion radiotherapy -- Part IV. Carbon-ion radiotherapy system -- Part V. Treatment planning of carbon-ion radiotherapy -- Part VI. Facility design -- Part VII. Oncology information system -- Part VIII. Evaluation of treatment outcome -- Part IX. Head and neck tumors -- Part X. Skull base and paracervical tumors -- Part XI. Eye tumors -- Part XII. Lung tumors -- Part XIII. GI tract tumors -- Part XIV. Liver tumors -- Part XV. Pancreatic cancer -- Part XVI. Genitourinary tumors -- Part XVII. Gynecologic tumors -- Part XVIII. Bone and soft tissue sarcomas -- Part XIX. Other tumors.
Format
e-Book
Location
Online
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Career Development in Academic Radiation Oncology

https://libcat.nshealth.ca/en/permalink/provcat46871
Ravi A. Chandra, Neha Vapiwala, Charles R. Thomas Jr. Springer , 2021.
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Location
Online
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Responsibility
Ravi A. Chandra, Neha Vapiwala, Charles R. Thomas Jr.
Publisher
Springer
Date of Publication
2021
Physical Description
1 online resource (xviii, 456 pages) : illustrations
ISBN
9783030718558
Specialty
Medical Oncology
Radiotherapy
Format
e-Book
Location
Online
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Chronic radiation syndrome

https://libcat.nshealth.ca/en/permalink/provcat33705
Alexander V. Akleyev. --Heidelberg: Springer , c2014.
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Location
Online
This book covers all aspects of chronic radiation syndrome (CRS) based on observations in a unique sample of residents of the Techa riverside villages in the southern Urals who were exposed to radioactive contamination in the 1950s owing to releases of liquid radioactive wastes from Mayak Production Association, which produced plutonium for weapons. In total, 940 cases of CRS were diagnosed in this population and these patients were subjected to detailed analysis. The opening chapters address t…
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Author
Akleev, A. V
Responsibility
Alexander V. Akleyev
Place of Publication
Heidelberg
Publisher
Springer
Date of Publication
c2014
Physical Description
1 online resource (xxi, 410 pages)
ISBN
9783642451171 (electronic bk.)
9783642451164
Subjects (MeSH)
Chronic Disease
Radiation Injuries - etiology
Radiation Injuries - therapy
Subjects (LCSH)
Radiation injuries
Radiotherapy
Hematology
Other Subjects
Russia
Abstract
This book covers all aspects of chronic radiation syndrome (CRS) based on observations in a unique sample of residents of the Techa riverside villages in the southern Urals who were exposed to radioactive contamination in the 1950s owing to releases of liquid radioactive wastes from Mayak Production Association, which produced plutonium for weapons. In total, 940 cases of CRS were diagnosed in this population and these patients were subjected to detailed analysis. The opening chapters address the definition and classification of CRS, epidemiology and pathogenesis, covering molecular and cellular mechanisms, radioadaptation, and the role of tissue reactions. The pathoanatomy of CRS during the development and recovery stages is discussed for all organ systems. Clinical manifestations of CRS at the different stages are then described in detail and the dynamics of hematopoietic changes are thoroughly examined. In the following chapters, principles of diagnosis (including assessment of the exposure doses to critical organs) and differential diagnosis from a wide range of other conditions are discussed and current and potential treatment options, described. The medical and social rehabilitation of persons with CRS is also covered. This book, which casts new light on the condition, will be of value for all practitioners and researchers with an interest in CRS.
Contents
1. Definition, Classification, and Clinical Presentation of Chronic Radiation Syndrome (CRS) Associated with Total Exposure to External Radiation -- 2. Epidemiology of Chronic Radiation Syndrome -- 3. Mechanisms Involved in Chronic Radiation Exposure Effects: Pathogenesis of Chronic Radiation Syndrome -- 4. Pathoanatomy of Chronic Radiation Syndrome During the Period of Its Development and at Recovery Stage -- 5. Clinical Manifestations of Chronic Radiation Syndrome -- 6. Dynamics of Hematopoietic Changes in Persons with CRS -- 7. Diagnosis of Chronic Radiation Syndrome -- 8. Treatment of Persons with CRS -- 9. General Conclusions.
Format
e-Book
Location
Online
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Clinical Applications of Nuclear Medicine Targeted Therapy

https://libcat.nshealth.ca/en/permalink/provcat42889
edited by Emilio Bombardieri, Ettore Seregni, Laura Evangelista, Carlo Chiesa, Arturo Chiti. --Cham: Springer , c2018.
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This book offers a practical and modern update on radioisotope therapy. Clinically oriented, it provides a thorough guide to patient management, with the latest indications and procedures for the current radioisotopic treatments. It addresses the clinical problems associated with each respective pathology, discussing the management of patients (diagnosis and non-radioisotope therapy), the radiopharmaceuticals available today, and the current radioisotopic procedures. Wherever possible, informat…
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Other Authors
Bombardieri, Emilio
Seregni, Ettore
Evangelista, Laura
Chiesa, Carlo
Chiti, Arturo
Responsibility
edited by Emilio Bombardieri, Ettore Seregni, Laura Evangelista, Carlo Chiesa, Arturo Chiti
Place of Publication
Cham
Publisher
Springer
Date of Publication
c2018
Physical Description
1 online resource (xiv, 503 p.) : 108 illus., 73 illus. in color
ISBN
9783319630670
9783319630663 (print ed.)
9783319630687 (print ed.)
Subjects (MeSH)
Nuclear Medicine - methods
Radioisotopes - therapeutic use
Radiopharmaceuticals - therapeutic use
Radiotherapy - methods
Specialty
Radiotherapy
Abstract
This book offers a practical and modern update on radioisotope therapy. Clinically oriented, it provides a thorough guide to patient management, with the latest indications and procedures for the current radioisotopic treatments. It addresses the clinical problems associated with each respective pathology, discussing the management of patients (diagnosis and non-radioisotope therapy), the radiopharmaceuticals available today, and the current radioisotopic procedures. Wherever possible, information on dosimetry is included at the end of each topic, together with a list of and comments on the most recent guidelines with their recommendations for radiometabolic therapy. The book is divided into six main sections: thyroid diseases, hepatic tumors (HCC and hepatic metastases), bone metastases from prostate cancer, lymphomas, and neuroendocrine tumors. The last section is dedicated to new perspectives of radioisotope treatment. Based on contributions from of a multidisciplinary team of specialists: oncologists, surgeons, endocrinologists, hematologists, urologists, radiopharmacists and nuclear medicine physicians, it provides a comprehensive analysis of the position of radioisotope treatments among the various therapeutic options. Readers interested in targeted therapy, radiometabolic therapy, radioimmunotherapy and radiometabolic imaging will find this book both informative and insightful.
Contents
THYROID DISEASES -- Diagnosis and treatment of hyperthyroidism (Endocrinologist) -- Radiopharmaceuticals for therapy of thyroid diseases ( chemistry, mechanism of uptake, biodistribution, doses) (Radiochemist) -- Radioiodine therapy of hyperthyroidism (indications , procedures and results) ( Nucl Medicine Physician) -- Dosimetry (Physicist) -- Clinical management of thyroid cancer (Oncologist) -- Radioidine therapy of thyroid cancer (ablation, loco-regional and distant metastases, indications procedures and results) (Nucl Medicine Physician) -- Dosimetry (Physicist) -- Novel approaches of radiometabolic treatment of thyroid cancer (Nucl Medicine Physician) -- Published guidelines on radioisotopic treatments of thyroid diseases (Nucl Medicine Physician and Oncologist) -- HEPATIC CANCER -- Clinical options for treatment of hepatocellular carcinoma (HCC) (Oncologist, Surge on) -- Radiopharmaceuticals for radioembolization (characteristics, mechanism of uptake, biodistribution, doses) (Radiochemist) -- HCC radioembolization with 90Y microspheres (indications and procedures) (Nucl Medicine Physician) -- Dosimetry (Physicist) -- The clinical problem of hepatic metastases (Oncologist, Surgeon) -- Radioembolization of hepatic metastases with 90Y microspheres (indications and procedures) (Nucl Medicine Physician) -- Dosimetry (Physicist) -- Published guidelines on radioisotope treatment of hepatocellular cancer (Nucl Medicine Physician and Oncologist) -- NEUROENDOCRINE TUMORS -- Radiopharmaceuticals for treatment of neuroendocrine tumors (mechanisn of action, biodistribution, doses) (Radiochemis inPaediatric tumors of neuroendocrine origin (Oncologist) -- Treatment with 131I—MIBG (indications procedures and results) (Nucl Medicine Physician) -- Dosimetry (Physicist) -- GEP neuroendocrine tumors (Oncologist) -- PPRT with 90Y labeled peptides (indications ,procedures and results) (Nucl Medicine Physician) -- Dosimetry (Physicist) -- Published guidelines on radioisotope treatment of Neuroendocrine tumors(Nucl Medicine Physician and Oncologist) -- LYMPHOMAS -- Selection of lymphoma patients candidates for Radioimmunotherapy (Haematologist) -- Radiopharmaceuticals for treatment of neuroendocrine tumors (mechanisn of action, biodistribution, doses) (Radiochemist) -- Treatment with anti-CD20 Antibodies ( 90Y- ibritumomab /131 I- Tositumomab) (indications and procedures and results) (Nucl Medicine Physician) -- Radioimmunotherapy at high doses of lymphomas (Nucl Medicine Physician) -- Published guidelines on radioisotope treatment of Lymphomas (Nucl Medicine Physician and Oncologist) -- PROSTATE CANCER -- Overview on bone metastases from prostate cancer (Urologist, Oncologist) -- Radiopharmaceuticals for treatment of bone metastases (mechanisn of action, biodistribution, doses) (Radiochemist) -- Targeted therapy with 223Ra dichloride of bone metastases(Nucl Medicine Physician) -- Novel approaches of treatment with 223Ra based targeted therapy (Nucl Medicine Physician) -- Dosimetry (Physicist) -- Published guidelines on radioisotope treatment of Bone Metastases (Nucl Medicine Physician and Oncologist).
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e-Book
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Clinical Nuclear Medicine

https://libcat.nshealth.ca/en/permalink/provcat30297
edited by Hans-Jürgen Biersack, Leonard M. Freeman. --Berlin, Heidelberg: Springer-Verlag , c2007.
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Author
Biersack, Hans-Jürgen
Other Authors
Freeman, Leonard M
Responsibility
edited by Hans-Jürgen Biersack, Leonard M. Freeman
Place of Publication
Berlin, Heidelberg
Publisher
Springer-Verlag
Date of Publication
c2007
ISBN
9783540280262
Subjects (MeSH)
Nuclear Medicine
Radionuclide Imaging
Radiopharmaceuticals - therapeutic use
Radiotherapy
Subjects (LCSH)
Nuclear medicine
Radiotherapy
Format
e-Book
Location
Online
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Clinical Nuclear Medicine

https://libcat.nshealth.ca/en/permalink/provcat45206
Hojjat Ahmadzadehfar, Hans-Jürgen Biersack, Leonard M. Freeman, Lionel S. Zuckier, editors. (Second edition) --Cham: Springer , c2020.
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In the new edition of this very successful book, European and North American experts present the state of the art in diagnostic and therapeutic radionuclide procedures. The aim is to examine established and emerging clinical applications in detail, rather than to consider everything included in the comprehensive texts already available within the field. This “practical” approach ensures that the book will be a valuable guide for nuclear medicine physicians, technologists, students, and interest…
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Other Authors
Ahmadzadehfar, Hojjat
Biersack, Hans-Jürgen
Freeman, Leonard M.
Zuckier, Lionel S.
Responsibility
Hojjat Ahmadzadehfar, Hans-Jürgen Biersack, Leonard M. Freeman, Lionel S. Zuckier, editors
Edition
Second edition
Place of Publication
Cham
Publisher
Springer
Date of Publication
c2020
Physical Description
1 online resource (ix, 1029 p.) : 494 illus., 280 illus. in color
ISBN
9783030394578
9783030394554 (Print ed.)
9783030394561 (Print ed.)
Subjects (MeSH)
Diagnostic Imaging - methods
Neoplasms - radiotherapy
Nuclear Medicine
Specialty
Diagnostic Imaging
Medical Oncology
Radiotherapy
Abstract
In the new edition of this very successful book, European and North American experts present the state of the art in diagnostic and therapeutic radionuclide procedures. The aim is to examine established and emerging clinical applications in detail, rather than to consider everything included in the comprehensive texts already available within the field. This “practical” approach ensures that the book will be a valuable guide for nuclear medicine physicians, technologists, students, and interested clinicians alike. This edition of Clinical Nuclear Medicine has been extensively revised to take account of recent developments. The roles of SPECT/CT, PET/CT, and PET/MRI are clearly explained and illustrated, and the coverage extended to encompass, for example, novel PET tracers and therapeutic radionuclides, advanced techniques of brain imaging, and the development of theranostics. Readers will be fully persuaded of the ever-increasing value of nuclear medicine techniques in depicting physiology and function and complementing anatomic modalities such as CT, MRI, and ultrasound.
Contents
Part I. Basics -- 1. Physics, instrumentation, and radiation safety and regulations -- 2. Radiopharmaceutical sciences -- 3. Radiomics as applied in precision medicine -- Part II. Diagnostic Nuclear Medicine -- 4. Brain -- 5. Heart -- 6. Lung -- 7. Liver, spleen and biliary tree -- 8. The kidney -- 9. Gastrointestinal system -- 10. Musculoskeletal system -- 11. Application of lymphatic mapping and sentinel node biopsy in surgical oncology -- 12. Lymphoscintigraphy in the management of the lymphatic disorders -- 13. Neuroendocrine system -- 14. Thyroid and parathyroid imaging -- 15. Molecular Imaging of Inflammation and Infection -- 16. Imaging of atherosclerosis with 18F-FDG PET -- 17. PET/CT and PET/MRI Imaging, Normal Variations and Artifacts -- 18. PET in head and neck cancer -- 19. PET in gastrointestinal, pancreatic, and liver cancers -- 20. 18F-FDG-PET/CT in breast and gynecologic cancer -- 21. PET in lung cancer and mediastinal malignancies -- 22. Melanoma -- 23. PET in lymphoma -- 24. PET/CT in renal, bladder and testicular cancer -- 25. PSMA-ligand imaging in the diagnosis of prostate cancer -- 26. Miscellaneous -- 27. Radionuclide imaging of children -- Part III. Nuclear Medicine Therapy -- 28. Radioiodine therapy for benign thyroid disease -- 29. Differentiated thyroid cancer: Radioiodine therapy -- 30. Palliation of metastatic bone pain with radiolabeled phosphonates -- 31. Radionuclide therapy of bone metastases with radium-223 chloride in prostate cancer patients -- 32. Peptide receptor radionuclide therapy -- 33. Treatment of neuroendocrine tumors (neuroblastoma stage III or IV, metastatic pheochromocytoma, etc.) with 131I-mIBG -- 34. Radioimmunotherapy -- 35. Radioactive microspheres -- 36. Radioembolization -- 37. Assessment of tumor response with MRI and CT after radioembolization -- 38. Radioisotope therapy of malignant pleural and peritoneal effusions -- 39. Radiosynoviorthesis (radiation synovectomy) -- 40. Radioligand therapy in prostate cancer using PSMA-ligands.
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e-Book
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Controversies in Radiation Oncology

https://libcat.nshealth.ca/en/permalink/provcat45397
Simon S. Lo, Bin S. Teh, Guo-Liang Jiang, Nina A. Mayr, editors. --Cham: Springer , c2020.
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This book addresses key issues of controversy in radiation oncology for each disease site, with expert commentaries from leading authorities in the field. It identifies areas of confusion arising from discrepant data in the literature regarding certain clinical scenarios for different diseases and presents high-level evidence on each issue with a view to fostering best practice. Controversies in Radiation Oncology will serve as a very useful resource for busy radiation oncology physicians, prac…
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Other Authors
Lo, Simon S.
Teh, Bin S.
Jiang, Guo-Liang
Mayr, Nina A.
Responsibility
Simon S. Lo, Bin S. Teh, Guo-Liang Jiang, Nina A. Mayr, editors
Place of Publication
Cham
Publisher
Springer
Date of Publication
c2020
Physical Description
1 online resource (vi, 298 p.) : 20 illus., 13 illus. in color
Series
Medical Radiology. Radiation Oncology
Series Title
Medical radiology (Series)
ISBN
9783319511962
9783319511948 (Print ed.)
9783319511955 (Print ed.)
Subjects (MeSH)
Neoplasms - radiotherapy
Radiation Oncology
Specialty
Radiotherapy
Abstract
This book addresses key issues of controversy in radiation oncology for each disease site, with expert commentaries from leading authorities in the field. It identifies areas of confusion arising from discrepant data in the literature regarding certain clinical scenarios for different diseases and presents high-level evidence on each issue with a view to fostering best practice. Controversies in Radiation Oncology will serve as a very useful resource for busy radiation oncology physicians, practitioners, and trainees/residents/fellows seeking to utilize evidence in the literature to guide the management of radiation therapy patients.
Contents
Breast cancer -- Head and neck cancer -- Non-small cell lung cancer -- Small cell lung cancer and other intrathoracic malignancies -- Sarcoma -- Prostate cancer -- Non-prostate genitourinary cancer -- Gynecologic cancer -- Esophageal and stomach cancers -- Colorectal cancer -- Hepatobiliary tract cancer -- Pancreatic cancer -- Hodgkin lymphoma -- Non-Hodgkin lymphoma -- Plasma cell tumors, myeloma and leukemia -- Brain metastasis -- Bone metastasis -- Visceral metastasis -- Gliomas -- Benign extraaxial primary brain tumors -- Pediatric central nervous system tumors -- Non-central nervous system pediatric cancers -- Skin cancer.
Format
e-Book
Location
Online
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Cured II, LENT : cancer survivorship research and education : late effects on normal tissues

https://libcat.nshealth.ca/en/permalink/provcat29503
edited by Philip Rubin, Louis S. Constine, Lawrence B. Marks, Paul Okunieff. --Berlin, Heidelberg: Springer-Verlag , c2008.
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Online
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Author
Rubin, Philip
Other Authors
Constine, Louis S
Marks, Lawrence B
Okunieff, Paul
Responsibility
edited by Philip Rubin, Louis S. Constine, Lawrence B. Marks, Paul Okunieff
Place of Publication
Berlin, Heidelberg
Publisher
Springer-Verlag
Date of Publication
c2008
Series
Medical radiology. Radiation oncology
Series Title
Medical radiology (Series)
ISBN
9783540762713
Subjects (MeSH)
Neoplasms - complications
Radiation Injuries
Radiotherapy - adverse effects
Treatment Outcome
Survivors
Subjects (LCSH)
Radiotherapy
Oncology
Format
e-Book
Location
Online
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