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Acrodermatitis Enteropathica : A Clinician's Guide

https://libcat.nshealth.ca/en/permalink/provcat39294
Pooya Khan Mohammad Beigi, Emanual Maverakis. --Cham: Springer , c2015.
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Written by and for dermatologists, pediatric and obstetrics specialists. This book presents the groundbreaking work of Dr. Pooya Khan Mohammad Beigi M.D., whose clinical research study on Acrodermatitis Enteropathica (AE) is the largest ever conducted on this rare disorder. The only book of its kind to offer insights into AE, it not only includes dozens of high quality photographs, illustrations, and clinical tables, but also covers everything from the history of AE to categories of the disorde…
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Author
Khan Mohammad Beigi, Pooya
Other Authors
Maverakis, Emanual
Responsibility
Pooya Khan Mohammad Beigi, Emanual Maverakis
Place of Publication
Cham
Publisher
Springer
Date of Publication
c2015
Physical Description
1 online resource (xxi, 156 p. : 56 illus., 51 illus. in color)
ISBN
9783319178196
9783319178189 (print ed.)
Subjects (MeSH)
Acrodermatitis
Zinc - deficiency
Abstract
Written by and for dermatologists, pediatric and obstetrics specialists. This book presents the groundbreaking work of Dr. Pooya Khan Mohammad Beigi M.D., whose clinical research study on Acrodermatitis Enteropathica (AE) is the largest ever conducted on this rare disorder. The only book of its kind to offer insights into AE, it not only includes dozens of high quality photographs, illustrations, and clinical tables, but also covers everything from the history of AE to categories of the disorder, molecular analysis, epidemiology, disorder signs and symptoms, diagnosis, treatment, and more. Acrodermatitis Enteropathica is a rare disorder of zinc metabolism that occurs in one of two forms: inborn and acquired. If untreated, this disease is fatal and affected individuals may die within just a few years. Therefore, it is critical that physicians are aware of the signs and symptoms related to AE and the appropriate treatments available for patients.
Contents
[publisher supplied] 1. History of Acrodermatitis Enteropathica -- 2. Epidemiology and Etiology -- 2.1. Epidemiology -- 2.2. Etiology -- 2.2.1. Molecular Etiology of AE -- 2.2.2. Hypothetical Etiology 1: the Alteration of Zinc Bioavailability -- 2.2.3. Hypothetical Etiology 2: a Defective Zinc Transporter -- 2.2.4. Alternative Forms of AE-like Zinc Deficiencies -- 3. Analysis of Disorder -- 3.1. Clinical Forms of AE -- 3.2. Nomenclature of Zinc Deficiencies -- 3.3. Acquired Non-hereditary Zinc Deficiency -- 3.3.1. Zinc Deficient Maternal Breast Milk -- 3.3.2. Zinc Deficient Caused by Metabolism Disorders -- 4. Clinical Symptoms -- 5. Diagnosis -- 5.1. Laboratory Diagnosis of Zinc Deficiency -- 5.2. Histopathology -- 5.3. Biological Diagnosis of AE -- 5.4. Clinical Diagnosis -- 5.5. Molecular Diagnosis -- 5.6. Differential Diagnosis -- 6. Disease Course and Treatment -- 6.1. Treatment -- 7. The Role of Zinc in Different Body Systems -- 7.1. Biochemistry of Zinc Metabolism -- 7.2. Skin and Hair Physiology -- 7.3. Gastrointestinal System and Other Organs -- 7.4. Neurological Development, Growth, and Mental Status -- 7.5. Enzymes -- 7.6. Endocrine System -- 7.7. Metabolism of Nucleic Acids -- 7.8. Mitosis and Meiosis Cycles -- 7.9. Cell Membranes -- 7.10. Synthesis of Proteins and Collagen -- 7.11. Immune System -- 8. History of AE in Adults -- 9. Iranian Hospital Cases in Literature -- 9.1. Patient One -- 9.2. Patient Two -- 9.3. Patient Three -- 9.4. Patient Four -- 9.5. Zinc Deficiency Similarities to AE in Infants (Fifth Patient) -- 10. Clinical Research -- 10.1. Abstract -- 10.2. Synopsis of Study -- 10.3. Purpose of Study -- 10.4. The Considered Hypotheses -- 10.5. Introduction -- 10.5. Methods -- 10.6. Ethical Considerations -- 10.7. Results -- 10.8. Discussion -- 11. Evaluation of Symptoms in Razi Dermatology Hospital -- 12. Case Photos.
Format
e-Book
Location
Online
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Alcohol, nutrition, and health consequences

https://libcat.nshealth.ca/en/permalink/provcat32449
Ronald Ross Watson, Victor R. Preedy, Sherma Zibadi, editors. --New York, NY: Humana Press , c2013.
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Alcohol, Nutrition, and Health Consequences provides practical, data-driven resources to help the reader understand the basics, treatments and preventive strategies that are involved in the understanding of how alcohol may affect healthy individuals as well as those with chronic alcohol use with or without relevant infectious diseases, obesity, diabetes and/or neurocognitive declines. It will also help the clinician define the causes and types of nutritional changes due to alcohol use and also …
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Other Authors
Watson, Ronald Ross
Preedy, Victor R
Zibadi, Sherma
Responsibility
Ronald Ross Watson, Victor R. Preedy, Sherma Zibadi, editors
Place of Publication
New York, NY
Publisher
Humana Press
Date of Publication
c2013
Physical Description
1 online resource (xxi, 578 p. : 70 ill., 8 ill. in color)
Series
Nutrition and Health
Series Title
Nutrition and health (Totowa, N.J.)
ISBN
9781627030472
Subjects (MeSH)
Alcohol-Related Disorders - complications
Ethanol - adverse effects
Ethanol - metabolism
Nutrition Disorders - etiology
Nutritional Physiological Phenomena
Subjects (LCSH)
Nutrition
Personal health and hygiene
Emergency medicine
Abstract
Alcohol, Nutrition, and Health Consequences provides practical, data-driven resources to help the reader understand the basics, treatments and preventive strategies that are involved in the understanding of how alcohol may affect healthy individuals as well as those with chronic alcohol use with or without relevant infectious diseases, obesity, diabetes and/or neurocognitive declines. It will also help the clinician define the causes and types of nutritional changes due to alcohol use and also explain how nutrition can be used to ameliorate its consequences. Chapters present the application of current nutritional knowledge by physicians and dietitians. Specific areas involving alcohol-related damage due to nutritional changes are reviewed, including heart disease, obesity, digestive tract cancers, lactation, brain function, and liver disease. In addition, alcohol's effects on absorption of minerals and nutrients, a key role in causing damage are treated. The importance of diet in modifying alcohol and its metabolite damage is also explained. Alcohol, Nutrition, and Health Consequences is essential reading for alcohol therapists and researchers as well as primary care physicians and dietitians and is an easy reference to help the clinician, student, and dietitian comprehend the complex changes caused by direct and indirect effects of ethanol at the cellular level via its nutritional modification.
Contents
Alcoholic and Nutrition: an Overview -- Genetics of alcohol metabolism -- Laboratory models available to study alcohol and nutrition -- Ethanol-induced lipid peroxidation and apoptosis in embryopathy -- Alcohol Use During Lactation: Effects on the Mother Infant Dyad -- Moderate alcohol administration: oxidative stress and nutritional status -- Alcohol use and abuse: Effects on Body Weight and body composition -- Alcohol Nutrition and health inequalities -- The effect of diet on protein modification by ethanol metabolites -- Vitamin B12 deficiency in alcoholics -- Alcohol American Indians/Alaskan Natives and Alcohol: Biology, Nutrition and Positive Programs -- Metabolism of Ethanol to Acetaldehyde in the Rat Mammary Tissue. Inhibitory Effects of Plant Polyphenols and Folic Acid -- Dietary zinc supplementation and prenatal ethanol exposure -- Tocotrienol and cognitive dysfunction induced by alcohol -- Soy Products Affecting Alcohol Absorption and Metabolism -- Oats supplementation and alcohol-induced oxidative tissue damage -- Fish oil n-3 fatty acids to prevent hippocampus and cognitive dysfunction in experimental alcoholism -- Alcohol in HIV and possible interactions with antiretroviral medications -- Popular energy drinks and alcohol -- The psychological synergistic effects of alcohol and caffeine -- Alcohol and Smoking: A correlation of use in youth? -- Are there Physiological Correlations between alcohol and tobacco use in adults? -- Alcohol, HIV/AIDS and Liver Disease -- Nutritional status, socioeconomic factors, alcohol and cataracts -- Alcohol Intake and High Blood Pressure -- Alcohol and dyslipidemia -- Dietary antioxidants in chronic alcoholic pancreatitis -- Alcohol consumption, lifestyle factors and risk of type 2 diabetes -- Alcohol, overweight, and obesity -- Nutrition alcohol and anorectic and bulimic adolescents -- Viral infections and cancer during alcohol use -- Ethanol and hepatocarcinogenesis -- Alcohol, diet and their interaction in colorectal and urinary tract tumors -- Alcohol, acetaldehyde and digestive tract cancer -- Alcohol Intake and Esophageal Cancer: Epidemiologic Evidence -- A Nutritional approach to prevent alcoholic liver disease -- Nutraceutical potential of indigenous plant foods and herbs for treatment of alcohol related Liver damage -- Alcohol and nutrition as risk factors for chronic liver disease -- Alcohol-related liver disease: Roles of insulin resistance, lipotoxic ceramide accumulation and endoplasmic reticulum stress -- Nutrition and alcoholic and non-alcoholic fatty liver disease: The significance of cholesterol -- Dietary fatty acids and alcoholic liver disease -- Nutrition in alcoholic steatohepatitis -- Alcoholic and non-alcoholic fatty liver disease and vitamin A.
Format
e-Book
Location
Online
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The alkaloids : volume 74 - chemistry and biology

https://libcat.nshealth.ca/en/permalink/provcat34096
edited by Hans Joachim Knolker. --Amsterdam, Netherlands: Elsevier , c2015.
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For more than 60 years, The Alkaloids has been the leading book series in the field of alkaloid chemistry. In more than 70 volumes all aspects of alkaloids, including chemistry, biology and pharmacology, have been covered in high-quality timeless reviews written by renowned experts in the field.
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Other Authors
Knolker, Hans Joachim
Responsibility
edited by Hans Joachim Knolker
Place of Publication
Amsterdam, Netherlands
Publisher
Elsevier
Date of Publication
c2015
Physical Description
1 online resource, 438 p.
Series Vol.
74
ISBN
9780128023563
Subjects (MeSH)
Alkaloids
Subjects (LCSH)
Alkaloids
Notes
Originally in Japanese
Abstract
For more than 60 years, The Alkaloids has been the leading book series in the field of alkaloid chemistry. In more than 70 volumes all aspects of alkaloids, including chemistry, biology and pharmacology, have been covered in high-quality timeless reviews written by renowned experts in the field.
Contents
Alkaloids derived from phenylalanine and tyrosine -- Alkaloids derived from tryptophan -- Alkaloids derived from ornithine and arginine -- Alkaloids derived from lysine -- Alkaloids derived from proline -- Alkaloids derived from glutamic acid -- Alkaloids derived from histidine -- Alkaloids derived from 2,3-diamino- propionic acid -- Compounds derived from anthranilic acid -- Alkaloids derived from nicotinic acid -- Alkaloids derived from nucleic acids and related compound -- Alkaloids possessing the porphine skeleton -- Alkaloids derived from a M-C7N unit -- Alkaloids derived from terpenoids -- Alkaloids derived from polyketides -- Alkaloids derived from a C6-C1 unit.
Format
e-Book
Location
Online
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Alkaptonuria and Ochronosis

https://libcat.nshealth.ca/en/permalink/provcat39212
Jozef Rovensk©, Tibor Urb©nek, Boldi¿ov© Oga, James A. Gallagher, editors. --Cham: Springer , c2015.
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This book comprehensively describes alkaptonuria and ochronosis. Beginning with the history, genetics, pathophysiology and diagnostics of the disease, the authors subsequently present a detailed characterization of its clinical manifestation in the spine, peripheral joints, eyes, ears, visceral organs and respiratory tract, its pathological anatomy and histology, as well as differential diagnosis. This is complemented by the latest data on therapy and experimental models of alkaptonuria, and su…
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Other Authors
Rovensk©, Jozef
Urb©nek, Tibor
Oga, Boldi¿ov©
Gallagher, James A
Responsibility
Jozef Rovensk©, Tibor Urb©nek, Boldi¿ov© Oga, James A. Gallagher, editors
Place of Publication
Cham
Publisher
Springer
Date of Publication
c2015
Physical Description
1 online resource (viii, 156 p. : 56 illus., 26 illus. in color)
ISBN
9783319151083
9783319151076 (print ed.)
Subjects (MeSH)
Alkaptonuria
Ochronosis
Abstract
This book comprehensively describes alkaptonuria and ochronosis. Beginning with the history, genetics, pathophysiology and diagnostics of the disease, the authors subsequently present a detailed characterization of its clinical manifestation in the spine, peripheral joints, eyes, ears, visceral organs and respiratory tract, its pathological anatomy and histology, as well as differential diagnosis. This is complemented by the latest data on therapy and experimental models of alkaptonuria, and supported by several case reports. Numerous pictures and radiological images document the clinical symptoms, giving the reader a solid understanding of the disease. On the basis of the editor's and authors' own extensive observations, the book offers an analysis of protein metabolism and aromatic amino acids in the context of alkaptonuria. Written by international experts in the field, the book offers a valuable reference guide for healthcare professionals working in rheumatology, dermatology, pulmonology, otolaryngology and histopathology.
Contents
Introduction -- Alkaptonuria and Ochronosis -- History -- Metabolism of Aromatic Amino Acids -- Tyrosine Metabolism Disorders -- Detection of Homogentisic Acid in Plasma and Urine -- Alkaptonuria Genetics -- Experimental Alkaptonuria in Animals -- Experimental Models of Alkaptonuria and Ochronosis -- Ochronotic Arthropathy -- Clinical Manifestation of Ochronotic Arthropathy in the Spine -- Analysis of X-Ray Symptomatology of Ochronotic Arthropathy in the Spine -- Clinical Manifestation of Ochronotic Arthropathy in the Peripheral Joints -- Clinical and Ultrasound Evaluation of Enthesopathy in Alkaptonuria in the Romani Community -- Analysis of X-Ray Symptomatology of Ochronotic Arthropathy in the Area of the Peripheral Joints -- Manifestations of Alkaptonuric Ochronosis in the Eye -- Symptoms of Alkaptonuria and Ochronosis in the Ear -- Manifestations of Alkaptonuria and Ochronosis in the Visceral Organs -- Manifestations of Alkaptonuria and Ochronosis in the Respiratory Tract -- Pathological Anatomy and Histology of Ochronosis -- Cellular and Molecular Patholgenesis of Ochronosis -- Picture of Synovial Effusion in Ochronosis -- Coincidence of Alkaptonuric Ochronosis with Other Diseases -- Differential Diagnosis of the Disease -- Sine Syndromes in Alkaptonuria -- History of Nitisinone (NTBC) -- Case Reports -- References.
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e-Book
Location
Online
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Amino acid metabolism and its disorders

https://libcat.nshealth.ca/en/permalink/provcat52798
Scriver, Charles R. --Philadelphia, PA: Saunders , 1973.
Call Number
RJ 399 A45 S38 1973
Location
IWK Health Sciences Library
Call Number
RJ 399 A45 S38 1973
Author
Scriver, Charles R.
Other Authors
Rosenberg, Leon E.
Place of Publication
Philadelphia, PA
Publisher
Saunders
Date of Publication
1973
Physical Description
xi, 491 p. : ill.
Series Title
Major problems in clinical pediatrics ; v.10
Subjects (MeSH)
Amino Acids - metabolism
D-Amino Acid Oxidase
Format
Book
Location
IWK Health Sciences Library
Copies
1
Loan Period
2 weeks
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Apolipoprotein Mimetics in the Management of Human Disease

https://libcat.nshealth.ca/en/permalink/provcat39279
G.M. Anantharamaiah, Dennis Goldberg, editors. --Cham: Springer International Publishing : Imprint: Adis , c2015.
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This comprehensive book provides not only the stages in the development of this unique and specialized field but also updates on the current state of research and development of apolipoprotein mimetics as therapeutic modalities for various lipid-mediated disorders. The book consists of 11 chapters all written by leading scientists from well-reputed laboratories in the USA. After an introduction by Dr. Godfrey Getz, Professor of Medicine at the University of Chicago and the Associate Editor of t…
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Other Authors
Anantharamaiah, G.M
Goldberg, Dennis
Responsibility
G.M. Anantharamaiah, Dennis Goldberg, editors
Place of Publication
Cham
Publisher
Springer International Publishing : Imprint: Adis
Date of Publication
c2015
Physical Description
1 online resource (xxi, 182 p. : 42 illus., 22 illus. in color)
ISBN
9783319173504
9783319173498 (print ed.)
Subjects (MeSH)
Apolipoproteins - therapeutic use
Biomimetics
Abstract
This comprehensive book provides not only the stages in the development of this unique and specialized field but also updates on the current state of research and development of apolipoprotein mimetics as therapeutic modalities for various lipid-mediated disorders. The book consists of 11 chapters all written by leading scientists from well-reputed laboratories in the USA. After an introduction by Dr. Godfrey Getz, Professor of Medicine at the University of Chicago and the Associate Editor of the Journal Lipid Research, the book presents a narration of how a theory can lead to the discovery of treatment modalities to several devastating diseases such as diabetes, Alzheimer's disease, arthritis; asthma; atherosclerosis, chronic rejection of transplanted hearts and cancer. Present therapies for most of these diseases are not adequate. Using the models of two long anti-atherogenic and anti-inflammatory proteins (apolipoprotein A-I and apolipoprotein E with 243 and 299 amino acids, respectively) short mimetic peptides of 18 to 28 amino acid residues in length, which can be produced either synthetically or genetically in edible fruits and vegetables, have been shown to exert profound biological effects in a large number of animal models of diseases. The book also presents novel ideas, highly unexpected mechanisms of action in animal models and even in initial clinical studies in humans, which can lead to additional improvements in basic and clinical research in biological science. All the chapters are written by experts in their respective fields who have contributed immensely to the literature. This is the first compendium of this growing field presented in the form of a book.
Contents
1. HDL and the Amphipathic Helix -- 2. ApoA-I mimetic peptides: A review of the present status -- 3. Apolipoprotein Mimetic Peptides for Stimulating Cholesterol Efflux -- 4. ApoA-I Mimetic Peptides and Diabetes -- 5. Apolipoprotein A-I mimetic peptides in Mouse Models of Cancer -- 6. Effects of ApoA-I mimetic peptide L-4F in LPS-mediated inflammation -- 7. Apolipoprotein mimetics in the amelioration of respiratory inflammation -- 8. Regulation of Macrophage Polarity by HDL, Apolipoproteins And Apolipoprotein Mimetic Peptides -- 9. Apolipoprotein E & Atherosclerosis: Beyond Lipid Effects -- 10. Apolipoprotein E mimetic peptides: Cholesterol dependent and independent properties -- 11. Apolipoprotein-E and Mimetics as Targets and Therapeutics for Alzheimer's Disease.
Format
e-Book
Location
Online
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Bile acid biology and its therapeutic implications

https://libcat.nshealth.ca/en/permalink/provcat21893
Paumgartner, G. --Dordrecht, Netherlands: Springer , 2005.
Call Number
WI 703 B595 2005
Location
Dickson Building
Call Number
WI 703 B595 2005
Author
Paumgartner, G
Other Authors
Falk Symposium (141 : 2004 : Stockholm, Sweden)
International Bile Acid Meeting (18th : 2004 : Stockholm, Sweden)
Place of Publication
Dordrecht, Netherlands
Publisher
Springer
Date of Publication
2005
Physical Description
270 p.
Series Vol.
141
Series Title
Falk symposium (series)
ISBN
1402028938
Subjects (MeSH)
Bile Acids and Salts - Congresses
Format
Book
Location
Dickson Building
Loan Period
3 weeks
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Bile Acids in Gastroenterology : Basic and Clinical

https://libcat.nshealth.ca/en/permalink/provcat41921
Susumu Tazuma, Hajime Takikawa, editors. --Tokyo: Springer , 2017.
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This book examines the biological aspects of bile acid analysis and their clinical applications, providing readers with an overview of cutting-edge discussions on Bile Acid research and diseases. It begins with detailed discussions on the biological aspects of bile acid, with chapters examining bile acid from various perspectives, from its metabolism to its use in therapeutic agents. Subsequent chapters focus on diseases involving bile acid abnormalities, and specific applications are addressed…
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Other Authors
Tazuma, Susumu
Takikawa, Hajime
Responsibility
Susumu Tazuma, Hajime Takikawa, editors
Place of Publication
Tokyo
Publisher
Springer
Date of Publication
2017
Physical Description
1 online resource (viii, 209 pages) : 39 illus., 20 illus. in color
ISBN
9784431560623
9784431560609 (print ed.)
Subjects (MeSH)
Bile Acids and Salts - physiology
Bile Acids and Salts - therapeutic use
Digestive System Diseases
Abstract
This book examines the biological aspects of bile acid analysis and their clinical applications, providing readers with an overview of cutting-edge discussions on Bile Acid research and diseases. It begins with detailed discussions on the biological aspects of bile acid, with chapters examining bile acid from various perspectives, from its metabolism to its use in therapeutic agents. Subsequent chapters focus on diseases involving bile acid abnormalities, and specific applications are addressed concerning gallstones, cholestatic liver disease, NAFLD/NASH, hepatitis, pancreatitis, esophageal cancer and colon cancer. In keeping with the book's integrated approach, the Editor has gathered a broad range of eminent scholars and practitioners to provide a comprehensive review of modern bile acid research. The book offers clinical physicians, basic researchers and postgraduate students essential insights into cutting-edge research and paves the way for further research.
Contents
Part I: Biological Aspects of Bile Acids -- 1. Metabolism of Bile Acids -- 2. Hepatobiliary Transport of Bile Acids -- 3. Intestinal Digestion and Absorption -- 4. Nuclear Receptor Regulation -- 5. Bile Acid as Therapeutic Agents -- Part II: Bile Acids and Diseases -- 6. Bile Acids and Gallstones: Epidemiology, Pathogenesis, Diagnosis and Management -- 7. Bile Acids and Cholestatic Liver Disease 1: Primary Biliary Cholangitis (PBC) -- 8. Bile Acids and Cholestatic Liver Disease 2: Primary Sclerosing Cholangitis -- 9. Bile Acids and Cholestatic Liver Disease 3: Inborn Errors of Bile Acid Synthesis -- 10. Bile Acids and NAFLD/NASH -- 11. Bile Acids and Viral Hepatitis and Hepatocellular Carcinoma -- 12. Bile Acids and Pancreatic Disease -- 13. Bile Acids and Esophageal Cancer -- 14. Bile Acid and Colorectal Cancer -- 15. Bile Acids and Metabolic Syndrome.
Format
e-Book
Location
Online
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Biochemistry for Anesthesiologists and Intensivists

https://libcat.nshealth.ca/en/permalink/provcat45100
Fernando Alemanno, editor. --Cham: Springer , c2020.
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This book discusses and explains the importance of biochemistry knowledge in understanding what happens to patients during anesthesia and/or to those being in intensive care. Anesthesiological and intensive care practice require a detailed biochemistry knowledge to avoid onset of complications and/or to deal with unexpected events promptly and appropriately. The book is intended for anesthesiologists, intensivists, anesthesia teachers, anesthesia trainees and residents.
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Other Authors
Alemanno, Fernando
Responsibility
Fernando Alemanno, editor
Place of Publication
Cham
Publisher
Springer
Date of Publication
c2020
Physical Description
1 online resource (xiv, 250 p.) : 65 illus., 22 illus. in color
ISBN
9783030267216
9783030267209 (Print ed.)
9783030267223 (Print ed.)
9783030267230 (Print ed.)
Subjects (MeSH)
Anesthesia
Anesthetics - adverse effects
Anesthetics - pharmacology
Biochemical Phenomena
Critical Care
Specialty
Anesthesiology
Biochemistry
Abstract
This book discusses and explains the importance of biochemistry knowledge in understanding what happens to patients during anesthesia and/or to those being in intensive care. Anesthesiological and intensive care practice require a detailed biochemistry knowledge to avoid onset of complications and/or to deal with unexpected events promptly and appropriately. The book is intended for anesthesiologists, intensivists, anesthesia teachers, anesthesia trainees and residents.
Contents
1. Enzymes and Coenzymes (A Brief, Boring but Necessary Preamble) -- 2. Anaerobic Glycolysis or Embden–Meyerhof Pathway -- 3. Tricarboxylic Acids Cycle or Krebs Cycle -- 4. Glutamate – GABA Collateral Cycle -- 5. Hexose-Monophosphate Shunt or Horecker Cycle (The Sleep Pathway) -- 6. Neurotransmitters -- 7. The Blood-Brain Barrier (BBB) -- 8. Shock -- 9. Cerebral Edema -- 10. The Pulmonary Surfactant -- 11. When the Mind Does Not Work As It Should -- 12. Thiamine (Vitamin B1) -- 13. Normobaric Oxygen Therapy (NBO) -- 14. Acid-Base Equilibrium -- 15. Theories of Narcosis -- 16. Local Anaesthetics -- 17. Perineural Adjuvants -- 18. The Grand Design -- 19. Epilogue and Farewell.
Format
e-Book
Location
Online
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Botulinum Toxins, Fillers and Related Substances

https://libcat.nshealth.ca/en/permalink/provcat44545
Maria Claudia Almeida Issa, Bhertha Tamura, editors. --Cham: Springer , c2019.
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The series “Clinical Approach and Procedures in Cosmetic Dermatology” intends to be a practical guide in Cosmetic Dermatology.  Procedures in cosmetic dermatology are very popular and useful in medicine, indicated to complement topical and oral treatments not only for photodamaged skin but also for other dermatosis such as acne, rosacea, scars, etc. Also, full-face treatments using peelings, lasers, fillers and toxins are increasingly being used, successfully substituting or postponing the need…
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Other Authors
Issa, Maria Claudia Almeida
Tamura, Bhertha
Responsibility
Maria Claudia Almeida Issa, Bhertha Tamura, editors
Place of Publication
Cham
Publisher
Springer
Date of Publication
c2019
Physical Description
1 online resource (700 p.) : 100 illus. in color
Series Title
Springer reference
Clinical approaches and procedures in cosmetic dermatology
ISBN
9783319202532
ISSN
2511-820X
Subjects (MeSH)
Botulinum Toxins - therapeutic use
Cosmetic Techniques
Dermal Fillers
Hyaluronic Acid - therapeutic use
Specialty
Cosmetic Techniques
Pharmacy
Notes
"Living reference work."
Abstract
The series “Clinical Approach and Procedures in Cosmetic Dermatology” intends to be a practical guide in Cosmetic Dermatology.  Procedures in cosmetic dermatology are very popular and useful in medicine, indicated to complement topical and oral treatments not only for photodamaged skin but also for other dermatosis such as acne, rosacea, scars, etc. Also, full-face treatments using peelings, lasers, fillers and toxins are increasingly being used, successfully substituting or postponing the need for plastic surgeries. Altogether, these techniques not only provide immediate results but also help patients to sustain long-term benefits, both preventing/treating dermatological diseases and maintaining a healthy and youthful skin. Throughout this series, different treatments in Cosmetic Dermatology will be discussed in detail covering the use of many pharmacological groups of cosmeceuticals, the new advances in nutraceuticals and emerging technologies and procedures. This volume, entitled “Botulin Toxin, Fillers and Related Substances” addresses the most important chemical approaches in cosmetic dermatology. Here are discussed in detail the use of Botulinum toxins and fillers, such as hyaluronic and polilatic acids.
Contents
Botulinum Toxin for Forehead -- Botulinum Toxin for Glabella Area and Nose -- Botulinum Toxin for Hyperhidrosis in Palmoplantar Area -- Botulinum Toxin for Hyperhidrosis in the Axillary Area -- Botulinum Toxin for Hyperhidrosis of Uncommon Areas -- Botulinum Toxin for Mandibular Contour -- Botulinum Toxin for Mentum and Perioral Area -- Botulinum Toxin for Migraine -- Botulinum Toxin for New Indications -- Botulinum Toxin for Periorbicular Area -- Botulinum Toxin for the Décolletage -- Botulinum Toxin on the Neck -- Botulinum Toxin: Complications and Their Management -- Calcium Hydroxyapatite to Treat the Hands -- Calcium Hydroxylapatite to Treat the Face -- Facial Anatomy View for Aesthetic Botulinum Toxin Injection -- Facial Anatomy View for Aesthetic Fillers Injections -- Facial Nerve-Block Anesthesia in Cosmetic Dermatology -- Fillers and Collagen Stimulator for Body Rejuvenation and Cellulitis -- Fillers: Complications and Their Management -- Hyaluronic Acid Dermal Filler: Physical Properties and Its Indications -- Hyaluronic Acid Filler for Forehead, Temporal, and Periorbicular Regions -- Hyaluronic Acid Filler for the Lips and Perioral Area -- Hyaluronic Acid Filler for the Malar Area -- Hyaluronic Acid Fillers: Codifying the Face for Foundation, Reconstruction, and Refinement -- Hyaluronic Acid for Mental and Mandibular Contour -- Hyaluronic Acid for Skin Booster on the Face -- Hyaluronic Acid for Skinbooster® on the Neck and V Shape Neckline Area -- Hyaluronic Filler for Nose -- Injectable Soft Tissues with Fibroblasts and Mesenchymal Cells -- Microbotox, Mesobotox, Botulinum Toxin Microdroplets -- My Personal Experience with Botulinum Toxin -- My Personal Experience with Fillers -- Permanent Fillers -- Poly-l-Lactic Acid for Body Treatment -- Poly-l-Lactic Acid for Facial Treatment -- Thread Lifting -- Three-Dimensional Approach of Cosmetic Patient: Aging Gracefully.
Format
e-Book
Location
Online
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Branched chain amino acids in clinical nutrition. Volume 1

https://libcat.nshealth.ca/en/permalink/provcat33660
Rajkumar Rajendram, Victor R. Preedy, Vinood B. Patel, editors. --New York: Humana Press , c2015.
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This is the first volume in a 2-volume compendium that is the go-to source for both research- and practice-oriented information on the importance of branched chain amino acids in maintaining the nutritional status and overall health of individuals, especially those with certain disease conditions. Over 150 well recognized and respected contributors have come together to compile these up-to-date and well-referenced works. The volumes will serve the reader as the benchmarks in this complex area o…
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Other Authors
Rajendram, Rajkumar
Preedy, Victor R
Patel, Vinood B
Responsibility
Rajkumar Rajendram, Victor R. Preedy, Vinood B. Patel, editors
Place of Publication
New York
Publisher
Humana Press
Date of Publication
c2015
Physical Description
1 online resource (xxviii, 270 pages)
Series
Nutrition and Health
Series Title
Nutrition and health (Totowa, N.J.)
ISBN
9781493919239 (electronic bk.)
9781493919222
Subjects (MeSH)
Amino Acids, Branched-Chain
Nutritional Physiological Phenomena
Subjects (LCSH)
Amino acids - Metabolism
Amino acids - Pathophysiology
Abstract
This is the first volume in a 2-volume compendium that is the go-to source for both research- and practice-oriented information on the importance of branched chain amino acids in maintaining the nutritional status and overall health of individuals, especially those with certain disease conditions. Over 150 well recognized and respected contributors have come together to compile these up-to-date and well-referenced works. The volumes will serve the reader as the benchmarks in this complex area of interrelationships between dietary protein intakes and individual amino acid supplementation, the unique role of the branched chain amino acids in the synthesis of brain neurotransmitters, collagen formation, insulin and glucose modulation and the functioning of all organ systems that are involved in the maintenance of the body?s metabolic integrity. Moreover, the physiological, genetic and pathological interactions between plasma levels of branched chain amino acids and aromatic amino acids are clearly delineated so that students as well as practitioners can better understand the complexities of these interactions. Branched Chain Amino Acids in Clinical Nutrition: Volume 1 covers basic processes at the cellular level, inherited defects in branched chain amino acid metabolism, and experimental models of growth and disease states.
Contents
Part I. Basic Processes at the Cellular Level -- 1. Impact of dietary essential amino acids in man -- 2. Metabolism of BCAAs -- 3. The cytosolic and mitochondrial branched chain aminotransferase -- 4. Isoleucine, PPAR and uncoupling proteins -- 5. Leucine as a stimulant of insulin -- 6. Effects of leucine and isoleucine on glucose metabolism -- 7. Hypothalamic leucine metabolism in the regulation of liver glucose metabolism -- 8. Leucine and resveratrol: experimental model of sirtuin pathway activation -- 9. Branched chain amino acids and blood ammonia -- 10. Use of 2H3-leucine to monitor apoproteins -- Part II. Inherited Defects in Branched Chain Amino Acid Metabolism -- 11. Branched chain amino acid oxidation disorders -- 12. Branched chain amino acids and maple syrup urine disease -- 13. Mental retardation and isoleucine metabolism -- 14. Anorexia and valine-deficient diets -- Part III. Experimental models of growth and disease states: Role of Branched Chain Amino Acids -- 15. Leucine and fetal growth -- 16. Enteral leucine and protein synthesis in skeletal and cardiac muscles -- 17. Use of branched chain amino acids granules in experimental models of diet-induced obesity -- 18. Experimental models of high fat obesity and leucine supplementation -- 19. Branched chain amino acids in experimental models of amyotrophic lateral sclerosis -- 20. Leucine and ethanol oxidation -- 21. Isoleucine, leucine and their role in experimental models of bladder carcinogenesis.
Format
e-Book
Location
Online
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Branched chain amino acids in clinical nutrition. Volume 2

https://libcat.nshealth.ca/en/permalink/provcat33659
Rajkumar Rajendram, Victor R. Preedy, Vinood B. Patel, editors. --New York: Humana Press , c2015.
Available Online
View e-Book
Location
Online
This is the second volume in a 2-volume compendium that is the go-to source for both research- and practice-oriented information on the importance of branched chain amino acids in maintaining the nutritional status and overall health of individuals, especially those with certain disease conditions. Over 150 well recognized and respected contributors have come together to compile these up-to-date and well-referenced works. The volumes will serve the reader as the benchmarks in this complex area …
Available Online
View e-Book
Other Authors
Rajendram, Rajkumar
Preedy, Victor R
Patel, Vinood B
Responsibility
Rajkumar Rajendram, Victor R. Preedy, Vinood B. Patel, editors
Place of Publication
New York
Publisher
Humana Press
Date of Publication
c2015
Physical Description
1 online resource (xxviii, 333 pages)
Series
Nutrition and Health
Series Title
Nutrition and health (Totowa, N.J.)
ISBN
9781493919147 (electronic bk.)
9781493919130
Subjects (MeSH)
Amino Acids, Branched-Chain
Nutritional Physiological Phenomena
Subjects (LCSH)
Amino acids - Synthesis
Amino acids - Physiological effect
Abstract
This is the second volume in a 2-volume compendium that is the go-to source for both research- and practice-oriented information on the importance of branched chain amino acids in maintaining the nutritional status and overall health of individuals, especially those with certain disease conditions. Over 150 well recognized and respected contributors have come together to compile these up-to-date and well-referenced works. The volumes will serve the reader as the benchmarks in this complex area of interrelationships between dietary protein intakes and individual amino acid supplementation, the unique role of the branched chain amino acids in the synthesis of brain neurotransmitters, collagen formation, insulin and glucose modulation and the functioning of all organ systems that are involved in the maintenance of the body?s metabolic integrity. Moreover, the physiological, genetic and pathological interactions between plasma levels of branched chain amino acids and aromatic amino acids are clearly delineated so that students as well as practitioners can better understand the complexities of these interactions. Branched Chain Amino Acids in Clinical Nutrition: Volume 2 covers the role of branched chain amino acids in healthy individuals, and branched chain amino acid status in disease states, liver diseases, and supplementation studies in certain patient populations.
Contents
Part I. Role of Branched Chain Amino Acids in Healthy Individuals -- 1. Tolerability of leucine -- 2. Leucine-protein supplemented recovery and exercise -- 3. Use of whey and leucine on muscle -- 4. Branched chain amino acids and muscle atrophy protection -- 5. Role of branched chain amino acids in cellular and organ damage: the prognostic significance of the preoperative branched chain amino acid to tyrosine ratio -- Part II. Branched Chain Amino Acids: Status in Disease States -- 6. Branched chain amino acids in heart failure -- 7. Mitochondrial tRNA valine in cardiomyopathies -- 8. Branched chain amino acids on psychomotor performance -- 9. The branch chain amino acids in the context of other amino acids in traumatic brain injury -- 10. Branched chain amino acids in chronic obstructive pulmonary disease -- Part III. Branched Chain Amino Acids and Liver Diseases -- 11. Identification of branched chain amino acids; underlying molecular pathways using transcriptomic analysis: application to cirrhosis -- 12. Branched chain amino acids supplementation and plasma albumin -- 13. Late evening snack, branched chain amino acids and cirrhosis -- 14. Branched chain amino acids and organ transplantation -- 15. Basic aspects in prevention of post-transplant bacteremia by branched chain amino acids -- 16. Branched chain amino acids and postoperative quality of life -- Part IV. Branched Chain Amino Acid Supplementation Studies in Certain Patient Populations -- 17. Leucine-protein functional adaptation in the clinical setting -- 18. Branched chain amino acids supplementation and glycemic control -- 19. Leucine supplementation and insulin resistance -- 20. Weight loss and branched chain amino acids and their metabolites -- 21. Branched chain amino acid cocktails and skin -- 22. Branched chain amino acids in inherited muscle disease: the case of Duchhene muscular dystrophy -- 23. Use of branched chain amino acids (BCAA) during radiotherapy -- 24. Oral branch chain amino acids and encephalopathy -- 25. Web based resources, and suggested readings.
Format
e-Book
Location
Online
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Cholesterol and beyond : the research on diet and coronary heart disease 1900–2000

https://libcat.nshealth.ca/en/permalink/provcat40975
A. Stewart Truswell. --Dordrecht: Springer , c2010.
Available Online
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Location
Online
Available Online
View e-Book
Author
Truswell, A. Stewart
Responsibility
A. Stewart Truswell
Place of Publication
Dordrecht
Publisher
Springer
Date of Publication
c2010
Physical Description
1 online resource (xvi, 227 p.)
ISBN
9789048188758
9789048188741 (print ed.)
Subjects (MeSH)
Cholesterol, Dietary - adverse effects
Coronary Disease - etiology
Coronary Disease - prevention & control
Diet, Atherogenic
Contents
1. Emergence of Coronary Heart Disease as a Diagnosis -- 2. Experimental Pathology in St. Petersburg -- 3. Is Plasma Cholesterol Raised with Human Atherosclerosis? -- 4. DietCan Have Worthwhile Effects on Human Plasma Cholesterol -- 5. A New Type of Observational Epidemiology -- 6. Serum Triglycerides? Another Risk Factor -- 7. Fredrickson’s Classification of the Hyperlipoproteinaemias -- 8. The Seven Countries Study (7CS) -- 9. Sucrose – An Alternative Dietary Hypothesis -- 10. HDL-Cholesterol Is Protective -- 11. Critics and Sceptics -- 12. Thrombosis on and in Atheroma -- 13. Dietary Cholesterol May Affect Plasma Cholesterol -- 14. First Controlled Trials -- 15. Dietary Fibre -- 16. Obesity -- 17. Thrombosis Treated Early -- 18. Fish Oil -- 19. Alcohol -- 20. Coffee -- 21. Trans-Fatty Acids -- 22. Antioxidants -- 23. More Controlled Dietary Trials -- 24. Trials of Better Drugs -- 25. Linoleic Acid Is Protective -- 26. Plant Sterols Fade and Return -- 27. Soy Proteins Versus Casein -- 28. High Homocysteine Associated with Cardiovascular Diseases -- 29. And Salt Should Be Included -- 30. How It Adds Up -- 31. The Big Picture -- 32. End Notes.
Format
e-Book
Location
Online
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Circulating Nucleic Acids in Early Diagnosis, Prognosis and Treatment Monitoring : An Introduction

https://libcat.nshealth.ca/en/permalink/provcat39543
Peter B. Gahan, editor. --Dordrecht: Springer Netherlands , c2015.
Available Online
View e-Book
Location
Online
DNA and RNA fractions can be isolated from a variety of body fluids including whole blood, serum, plasma, urine, saliva and cerebrospinal fluid from both patients and healthy individuals. Such isolates can be exploited in the early detection of clinical disorders, stratification of patients for treatment, treatment monitoring and clinical follow-up. In addition, the use in fetal medicine allows the early detection of fetal sex, Rh factor and aneuploid disorders as well as following both fetal a…
Available Online
View e-Book
Other Authors
Gahan, Peter B
Responsibility
Peter B. Gahan, editor
Place of Publication
Dordrecht
Publisher
Springer Netherlands
Date of Publication
c2015
Physical Description
1 online resource (xix, 471 p. : 59 illus., 39 illus. in color)
Series Vol.
v. 5
Series Title
Advances in predictive, preventive and personalised medicine
ISBN
9789401791687
9789401791670 (print ed.)
ISSN
2211-3495
Subjects (MeSH)
Genetic testing
Genomics
Molecular Diagnostic Techniques
Nucleic Acids - analysis
Nucleic Acids - isolation & purification
Abstract
DNA and RNA fractions can be isolated from a variety of body fluids including whole blood, serum, plasma, urine, saliva and cerebrospinal fluid from both patients and healthy individuals. Such isolates can be exploited in the early detection of clinical disorders, stratification of patients for treatment, treatment monitoring and clinical follow-up. In addition, the use in fetal medicine allows the early detection of fetal sex, Rh factor and aneuploid disorders as well as following both fetal and premature born infant development. This volume is intended as a primer for those who are interested in entering the field of circulating nucleic acids. The areas covered in this volume include: Background and general biology of circulating nucleic acids; Methodology; Applications of circulating nucleic acids; Quality Assurance; Ethics.
Contents
Part I. BACKGROUND -- 1. Introduction: Brief History and the present and future status of CNAPS -- 2. The biology of CNAPS -- Part II. METHODOLOGY -- 3. Pre-analytical requirements for analysing nucleic acids from blood -- 4. Circulating DNA and miRNA isolation -- 5. Detection of genetic alterations by nucleic acid analysis: use of pcr and mass spectroscopy-based methods -- 6. Genomic approaches to the analysis of cell free nucleic acids -- Part III APPLICATIONS -- 7. CNAPS and General Medicine -- 8. Fetal CNAPS: DNA/RNA -- 9. Circulating nucleic acids and Diabetes mellitus -- 10. Extracellular nucleic acids and cancer -- 11. Other bodily fluids as non-invasive sources of Cell-free DNA/RNA -- 12. CNAPS in therapy monitoring -- Part IV OTHER ASPECTCS -- 13. Quality Assurance -- 14. Societal Aspects: Ethics.
Format
e-Book
Location
Online
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Clinical Autonomic and Mitochondrial Disorders : Diagnosis, Prevention, and Treatment for Mind-Body Wellness

https://libcat.nshealth.ca/en/permalink/provcat44681
Nicholas L. DePace, Joseph Colombo. --Cham: Springer , c2019.
Available Online
View e-Book
Location
Online
This book establishes and specifies a rigorously scientific and clinically valid basis for nonpharmaceutical approaches to many common diseases and disorders found in clinical settings. It includes lifestyle and supplement recommendations for beginning and maintaining autonomic nervous system and mitochondrial health and wellness. The book is organized around a six-pronged mind-body wellness program and contains a series of clinical applications and frequently asked questions. The physiologic n…
Available Online
View e-Book
Author
DePace, Nicholas L.
Other Authors
Colombo, Joseph
Responsibility
Nicholas L. DePace, Joseph Colombo
Place of Publication
Cham
Publisher
Springer
Date of Publication
c2019
Physical Description
1 online resource (xxxii, 614 p.) : 336 illus., 314 illus. in color
ISBN
9783030170165
9783030170158 (Print ed.)
9783030170172 (Print ed.)
9783030170189 (Print ed.)
Subjects (MeSH)
Autonomic Nervous System Diseases - prevention & control
Health Promotion - methods
Mind-Body Therapies
Mitochondrial Diseases - prevention & control
Specialty
Health Promotion
Physiology
Abstract
This book establishes and specifies a rigorously scientific and clinically valid basis for nonpharmaceutical approaches to many common diseases and disorders found in clinical settings. It includes lifestyle and supplement recommendations for beginning and maintaining autonomic nervous system and mitochondrial health and wellness. The book is organized around a six-pronged mind-body wellness program and contains a series of clinical applications and frequently asked questions. The physiologic need and clinical benefit and synergism of all six aspects working together are detailed, including the underlying biochemistry, with exhaustive references to statistically significant and clinically relevant studies. The book covers a range of clinical disorders, including anxiety, arrhythmia, atherosclerosis, bipolar disease, dementia, depression, fatigue, fibromyalgia, heart diseases, hypertension, mast cell disorder, migraine, and PTSD. Clinical Autonomic and Mitochondrial Disorders: Diagnosis, Prevention, and Treatment for Mind-Body Wellness is an essential resource for physicians, residents, fellows, medical students, and researchers in cardiology, primary care, neurology, endocrinology, psychiatry, and integrative and functional medicine. It provides therapy options to the indications and diagnoses published in our book Clinical Autonomic Dysfunction (Springer, 2014).
Contents
1. Introduction -- 2. About the Program -- 3. Omega-3 Fatty Acids (Prong-1) - 4. Nitric Oxide (Prong-2) -- 5. Oxidative Stress Reduction (Prong-3) - 6. Mediterranean Diet (Prong-4) -- 7. Exercise (Prong-5) -- 8. Psychosocial Stress Reduction (Prong-6) -- 9. Mind-Body Wellness Program Benefits.
Format
e-Book
Location
Online
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Clinical handbook of psychotropic drugs

https://libcat.nshealth.ca/en/permalink/provcat42420
Ric M. Procyshyn, principal editor ; Kalyna Z. Bezchlibnyk-Butler, co-editor ; J. Joel Jeffries, co-editor. (22nd ed.) --Boston, MA: Hogrefe Publishing , c2017.
Call Number
QV 77 C641 2017 REF
Location
Nova Scotia Hospital
Cape Breton Regional
Aberdeen Hospital
Dickson Building
Halifax Infirmary
Sub-Location
REFERENCE
The Clinical Handbook of Psychotropic Drugs has become a standard reference and working tool for psychiatrists, psychologists, physicians, pharmacists, nurses, and other mental health professionals. Independent, unbiased. Packed with unique, easy-to-read comparison charts and tables (dosages, side effects, pharmacokinetics, interactions) for a quick overview of treatment options. Succinct, bulleted information on all classes of medication: on- and off-label indications, side effects, interactio…
Call Number
QV 77 C641 2017 REF
Other Authors
Procyshyn, Ric M.
Bezchlibnyk-Butler, Kalyna Z.
Jeffries, J. Joel
Responsibility
Ric M. Procyshyn, principal editor ; Kalyna Z. Bezchlibnyk-Butler, co-editor ; J. Joel Jeffries, co-editor
Edition
22nd ed.
Alternate Title
Psychotropic drugs
CHPD
Place of Publication
Boston, MA
Publisher
Hogrefe Publishing
Date of Publication
c2017
Physical Description
431 p.
ISBN
9781616764968
1616764961
Subjects (MeSH)
Psychotropic Drugs - administration and dosage
Psychotropic Drugs - therapeutic use
Abstract
The Clinical Handbook of Psychotropic Drugs has become a standard reference and working tool for psychiatrists, psychologists, physicians, pharmacists, nurses, and other mental health professionals. Independent, unbiased. Packed with unique, easy-to-read comparison charts and tables (dosages, side effects, pharmacokinetics, interactions) for a quick overview of treatment options. Succinct, bulleted information on all classes of medication: on- and off-label indications, side effects, interactions, pharmacodynamics, precautions in the young, the elderly, and pregnancy, nursing implications, and much more - all you need to know for each class of drug. Potential interactions and side effects summarized in comparison charts. With instantly recognizable icons and in full color throughout, allowing you to find at a glance all the information you seek. Clearly written patient information sheets available for download as printable PDF files.
Contents
Antidepressants -- Selective Serotonin Reuptake Inhibitors (SSRI) -- Norepinephrine Dopamine Reuptake Inhibitor (NDRI) -- Serotonin Norepinephrine Reuptake Inhibitor (SNRI) -- Serotonin-2 Antagonists/Reuptake Inhibitors (SARI) -- Serotonin-1A Agonist/Serotonin Reuptake Inhibitor -- Serotonin Stimulator/Serotonin Modulator -- Noradrenergic/Specific Serotonergic Antidepressants (NaSSA) -- Nonselective Cyclic Antidepressants -- Monoamine Oxidase Inhibitors -- Reversible Inhibitor of MAO-A (RIMA) -- Irreversible Monoamine Oxidase (A&B) Inhibitors (MAOIs) -- Irreversible MAO-B Inhibitor -- Effects of Antidepressants on Neurotransmitters/Receptors -- Pharmacological Effects of Antidepressants on Neurotransmitters/Receptors -- Frequency of Adverse Reactions to Antidepressants at Therapeutic Doses -- Antidepressant Doses and Pharmacokinetics -- Switching Antidepressants -- Antidepressant Augmentation Strategies -- Electroconvulsive Therapy (ECT) -- Bright Light Therapy (BLT) -- Repetitive Transcranial Magnetic Stimulation (rTMS) -- Antipsychotics -- "Second-Generation" Antipsychotics/SGAs -- "Third-Generation" Antipsychotic/TGA -- "First-Generation" Antipsychotics/FGAs -- Effects of Antipsychotics on Neurotransmitters/Receptors -- Pharmacological Effects of Antipsychotics on Neurotransmitters/Receptor Subtypes -- Relative Tolerability Profiles of Antipsychotics -- Frequency (%) of Adverse Reactions to Antipsychotics at Therapeutic Doses -- Antipsychotic Doses and Pharmacokinetics (Oral and Short-Acting Injections) -- Comparison of Long-Acting IM Antipsychotics -- Switching Antipsychotics -- Antipsychotic Augmentation Strategies -- Antipsychotic-Induced Extrapyramidal Side Effects and Their Management -- Extrapyramidal Adverse Effects of Antipsychotics -- Treatment Options for Extrapyramidal Side Effects -- Effects on Extrapyramidal Symptoms -- Comparison of Agents for Treating Acute Extrapyramidal Side Effects -- Doses and Pharmacokinetics of Agents for Treating Acute Extrapyramidal Side Effects -- Anxiolytic (Antianxiety) Agents -- Benzodiazepines -- Comparison of the Benzodiazepines -- Buspirone -- Hypnotics/Sedatives -- L-Tryptophan -- Comparison of Hypnotics/Sedatives -- Mood Stabilizers -- Lithium -- Anticonvulsants -- Comparison of Anticonvulsants -- Frequency of Adverse Reactions to Mood Stabilizers at Therapeutic Doses -- Drugs for ADHD -- Psychostimulants -- Atomoxetine -- Comparison of Drugs for ADHD -- a2 agonists -- Augmentation Strategies in ADHD -- Drugs for Treatment of Dementia -- Cholinesterase Inhibitors -- Memantine -- Comparison of Drugs for Treatment of Dementia -- Sex-Drive Depressants -- Comparison of Sex-Drive Depressants -- Drugs of Abuse -- Alcohol -- Stimulants -- Hallucinogens -- Opioids -- Inhalants/Aerosols -- Gamma-hydroxybutyrate (GHB)/Sodium Oxybate -- Flunitrazepam (Rohypnol) -- Nicotine/Tobacco -- Treatment of Substance Use Disorders -- Acamprosate -- Disulfiram -- Naltrexone -- Buprenorphine -- Methadone -- Pharmacotherapy for Nicotine/Tobacco Use Dependence -- Unapproved Treatments of Psychiatric Disorders -- Adrenergic Agents -- Dopaminergic Agents -- GABA Agents/Anticonvulsants -- Hormones -- NMDA Agents -- Miscellaneous -- Natural Health Products -- Ginkgo Biloba -- Inositol -- Kava Kava -- Melatonin -- Omega-3 Polyunsaturated Fatty Acids -- S-Adenosyl-L-methionine (SAMe) -- St. John's Wort -- Valerian -- Vitamins -- Pharmacogenomic Information for Common Psychotropic Drugs -- Antidepressants -- Antipsychotics -- Mood Stabilizers -- Drugs for Treatment of Dementia -- Opiate Receptor Ligands, Alcohol, Interferon -- Glossary -- Drug use in pregnancy and effects on breast milk -- Patient information sheets -- Appendix: Neuroscience-based nomenclature (NbN) -- Index of drugs.
Format
Book
Publication Type
Handbook
Location
Nova Scotia Hospital
Cape Breton Regional
Aberdeen Hospital
Dickson Building
Halifax Infirmary
Sub-Location
REFERENCE
Copies
5
Loan Period
In library use
Less detail

Clinical handbook of psychotropic drugs

https://libcat.nshealth.ca/en/permalink/provcat42494
Ric M. Procyshyn, principal editor ; Kalyna Z. Bezchlibnyk-Butler, co-editor ; J. Joel Jeffries, co-editor. (22nd ed.) --Boston, MA: Hogrefe Publishing , c2017.
Call Number
QV 77 C641 2017
Location
Yarmouth Regional Hospital
The Clinical Handbook of Psychotropic Drugs has become a standard reference and working tool for psychiatrists, psychologists, physicians, pharmacists, nurses, and other mental health professionals. Independent, unbiased. Packed with unique, easy-to-read comparison charts and tables (dosages, side effects, pharmacokinetics, interactions) for a quick overview of treatment options. Succinct, bulleted information on all classes of medication: on- and off-label indications, side effects, interactio…
Call Number
QV 77 C641 2017
Other Authors
Procyshyn, Ric M.
Bezchlibnyk-Butler, Kalyna Z.
Jeffries, J. Joel
Responsibility
Ric M. Procyshyn, principal editor ; Kalyna Z. Bezchlibnyk-Butler, co-editor ; J. Joel Jeffries, co-editor
Edition
22nd ed.
Alternate Title
Psychotropic drugs
CHPD
Place of Publication
Boston, MA
Publisher
Hogrefe Publishing
Date of Publication
c2017
Physical Description
431 p.
ISBN
9781616764968
1616764961
Subjects (MeSH)
Psychotropic Drugs - administration and dosage
Psychotropic Drugs - therapeutic use
Abstract
The Clinical Handbook of Psychotropic Drugs has become a standard reference and working tool for psychiatrists, psychologists, physicians, pharmacists, nurses, and other mental health professionals. Independent, unbiased. Packed with unique, easy-to-read comparison charts and tables (dosages, side effects, pharmacokinetics, interactions) for a quick overview of treatment options. Succinct, bulleted information on all classes of medication: on- and off-label indications, side effects, interactions, pharmacodynamics, precautions in the young, the elderly, and pregnancy, nursing implications, and much more - all you need to know for each class of drug. Potential interactions and side effects summarized in comparison charts. With instantly recognizable icons and in full color throughout, allowing you to find at a glance all the information you seek. Clearly written patient information sheets available for download as printable PDF files.
Contents
Antidepressants -- Selective Serotonin Reuptake Inhibitors (SSRI) -- Norepinephrine Dopamine Reuptake Inhibitor (NDRI) -- Serotonin Norepinephrine Reuptake Inhibitor (SNRI) -- Serotonin-2 Antagonists/Reuptake Inhibitors (SARI) -- Serotonin-1A Agonist/Serotonin Reuptake Inhibitor -- Serotonin Stimulator/Serotonin Modulator -- Noradrenergic/Specific Serotonergic Antidepressants (NaSSA) -- Nonselective Cyclic Antidepressants -- Monoamine Oxidase Inhibitors -- Reversible Inhibitor of MAO-A (RIMA) -- Irreversible Monoamine Oxidase (A&B) Inhibitors (MAOIs) -- Irreversible MAO-B Inhibitor -- Effects of Antidepressants on Neurotransmitters/Receptors -- Pharmacological Effects of Antidepressants on Neurotransmitters/Receptors -- Frequency of Adverse Reactions to Antidepressants at Therapeutic Doses -- Antidepressant Doses and Pharmacokinetics -- Switching Antidepressants -- Antidepressant Augmentation Strategies -- Electroconvulsive Therapy (ECT) -- Bright Light Therapy (BLT) -- Repetitive Transcranial Magnetic Stimulation (rTMS) -- Antipsychotics -- "Second-Generation" Antipsychotics/SGAs -- "Third-Generation" Antipsychotic/TGA -- "First-Generation" Antipsychotics/FGAs -- Effects of Antipsychotics on Neurotransmitters/Receptors -- Pharmacological Effects of Antipsychotics on Neurotransmitters/Receptor Subtypes -- Relative Tolerability Profiles of Antipsychotics -- Frequency (%) of Adverse Reactions to Antipsychotics at Therapeutic Doses -- Antipsychotic Doses and Pharmacokinetics (Oral and Short-Acting Injections) -- Comparison of Long-Acting IM Antipsychotics -- Switching Antipsychotics -- Antipsychotic Augmentation Strategies -- Antipsychotic-Induced Extrapyramidal Side Effects and Their Management -- Extrapyramidal Adverse Effects of Antipsychotics -- Treatment Options for Extrapyramidal Side Effects -- Effects on Extrapyramidal Symptoms -- Comparison of Agents for Treating Acute Extrapyramidal Side Effects -- Doses and Pharmacokinetics of Agents for Treating Acute Extrapyramidal Side Effects -- Anxiolytic (Antianxiety) Agents -- Benzodiazepines -- Comparison of the Benzodiazepines -- Buspirone -- Hypnotics/Sedatives -- L-Tryptophan -- Comparison of Hypnotics/Sedatives -- Mood Stabilizers -- Lithium -- Anticonvulsants -- Comparison of Anticonvulsants -- Frequency of Adverse Reactions to Mood Stabilizers at Therapeutic Doses -- Drugs for ADHD -- Psychostimulants -- Atomoxetine -- Comparison of Drugs for ADHD -- a2 agonists -- Augmentation Strategies in ADHD -- Drugs for Treatment of Dementia -- Cholinesterase Inhibitors -- Memantine -- Comparison of Drugs for Treatment of Dementia -- Sex-Drive Depressants -- Comparison of Sex-Drive Depressants -- Drugs of Abuse -- Alcohol -- Stimulants -- Hallucinogens -- Opioids -- Inhalants/Aerosols -- Gamma-hydroxybutyrate (GHB)/Sodium Oxybate -- Flunitrazepam (Rohypnol) -- Nicotine/Tobacco -- Treatment of Substance Use Disorders -- Acamprosate -- Disulfiram -- Naltrexone -- Buprenorphine -- Methadone -- Pharmacotherapy for Nicotine/Tobacco Use Dependence -- Unapproved Treatments of Psychiatric Disorders -- Adrenergic Agents -- Dopaminergic Agents -- GABA Agents/Anticonvulsants -- Hormones -- NMDA Agents -- Miscellaneous -- Natural Health Products -- Ginkgo Biloba -- Inositol -- Kava Kava -- Melatonin -- Omega-3 Polyunsaturated Fatty Acids -- S-Adenosyl-L-methionine (SAMe) -- St. John's Wort -- Valerian -- Vitamins -- Pharmacogenomic Information for Common Psychotropic Drugs -- Antidepressants -- Antipsychotics -- Mood Stabilizers -- Drugs for Treatment of Dementia -- Opiate Receptor Ligands, Alcohol, Interferon -- Glossary -- Drug use in pregnancy and effects on breast milk -- Patient information sheets -- Appendix: Neuroscience-based nomenclature (NbN) -- Index of drugs.
Format
Book
Publication Type
Handbook
Location
Yarmouth Regional Hospital
Loan Period
3 weeks use
Less detail

Clinical lipidology : a companion to Braunwald's heart disease

https://libcat.nshealth.ca/en/permalink/provcat33488
[edited by] Christie M. Ballantyne. (2nd ed.) --Philadelphia, PA: Elsevier Saunders , c2015.
Available Online
View e-Book
Access
Registration required for PDF access.
Location
Online
Clinical Lipidology, a companion to Braunwald’s Heart Disease, is designed to guide you through the ever-changing therapeutic management of patients with high cholesterol levels. From basic science to pathogenesis of atherothrombotic disease, to risk assessment and the latest therapy options, this medical reference book offers unparalleled coverage and expert guidance on lipidology in a straightforward, accessible, and user-friendly style.
Available Online
View e-Book
Other Authors
Ballantyne, Christie M
Responsibility
[edited by] Christie M. Ballantyne
Edition
2nd ed.
Place of Publication
Philadelphia, PA
Publisher
Elsevier Saunders
Date of Publication
c2015
Physical Description
1 online resource, 568 p.
ISBN
9780323324991
Subjects (MeSH)
Lipoproteins - metabolism
Cardiovascular Diseases - complications
Dyslipidemias
Lipid Metabolism
Subjects (LCSH)
Lipids
Lipoproteins
Heart - Diseases
Lipoproteins - metabolism
Cardiovascular Diseases - complications
Dyslipidemias
Lipid Metabolism
Notes
Complemented by: Braunwald's heart disease / edited by Douglas L. Mann, Douglas P. Zipes, Peter Libby, Robert O. Bonow, Eugene Braunwald. 10th edition. [2015]
Abstract
Clinical Lipidology, a companion to Braunwald’s Heart Disease, is designed to guide you through the ever-changing therapeutic management of patients with high cholesterol levels. From basic science to pathogenesis of atherothrombotic disease, to risk assessment and the latest therapy options, this medical reference book offers unparalleled coverage and expert guidance on lipidology in a straightforward, accessible, and user-friendly style.
Contents
Human plasma lipoprotein metabolism -- Regulation and clearance of apolipoprotein B-containing lipoproteins -- Absorption and excretion of intestinal cholesterol and other sterols -- High-density lipoprotein metabolism -- Lipoproteins : mechanisms for atherogenesis and progression of atherothrombotic disease -- Impact of rare and common genetic variants on lipoprotein metabolism -- Lipoprotein oxidation : mechanisms and biotheranostic applications -- Cholesterol : concentration, ratio, and particle number -- High-density lipoprotein cholesterol and triglycerides in coronary heart disease risk assessment -- Lipoprotein(a) -- Clinical evaluation for genetic and secondary causes of dyslipidemia -- Use of high-sensitivity c-reactive protein for risk assessment -- Role of lipoprotein-associated phospholipase A2 in vascular disease -- Emerging assays -- Imaging atherosclerosis for risk stratification by cardiac computed tomography or carotid ultrasound -- Overview of general approach to management of elevated low-density lipoprotein cholesterol and mixed dyslipidemia, high triglycerides, and low high-density lipoprotein cholesterol -- Treatment guidelines overview -- Dietary patterns for the prevention and treatment of cardiovascular disease -- Exercise and lipids -- Weight loss -- Statins -- Bile acid sequestrants -- Cholesterol absorption inhibitors -- Niacin (nicotinic acid) -- Fibrates -- Omega-3 fatty acids -- Combination therapy for dyslipidemia -- Nutraceuticals and functional foods for cholesterol reduction -- Evolving targets of therapy : cholesteryl ester transfer protein inhibition -- Evolving targets of therapy : proprotein convertase subtilisin/kexin 9 inhibition -- Evolving targets of therapy : inflammation as a method to predict and prevent cardiovascular events -- Invasive imaging modalities and atherosclerosis : intravascular ultrasound -- Noninvasive imaging modalities and atherosclerosis : the role of ultrasound -- Noninvasive imaging modalities and atherosclerosis : the role of magnetic resonance imaging and positron emission tomography imaging -- Special patient populations : diabetes and metabolic syndrome -- Special patient populations : women and elderly -- Special patient populations : children and adolescents -- Special patient populations : familial hypercholesterolemia and other severe hypercholesterolemias -- Special patient populations : acute coronary syndromes -- Special patient populations : transplant recipients -- Special patient populations : chronic kidney disease -- Special patient populations : lipid abnormalities in high-risk ethnic groups -- Special patient populations : human immunodeficiency virus patients -- Therapeutic targeting of high-density lipoprotein metabolism.
Access
Registration required for PDF access.
Format
e-Book
Location
Online
Less detail

Combination Therapy In Dyslipidemia

https://libcat.nshealth.ca/en/permalink/provcat39365
Maciej Banach, editor. --Cham: Springer International Publishing : Imprint: Adis , c2015.
Available Online
View e-Book
Location
Online
Comprising contributions from leading lipidologists from around the world, this book presents the latest and most comprehensive knowledge on the different options for combination therapy of dyslipidemia, and includes discussion of future therapies that are currently in late stages of clinical evaluation. Dyslipidemia is a leading cause of cardiovascular morbidity and mortality and most patients with this condition fail to achieve adequate control of their serum lipid levels with monotherapy. Ho…
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Other Authors
Banach, Maciej
Responsibility
Maciej Banach, editor
Place of Publication
Cham
Publisher
Springer International Publishing : Imprint: Adis
Date of Publication
c2015
Physical Description
1 online resource (viii, 205 p. : 22 illus., 15 illus. in color)
ISBN
9783319204338
9783319204321 (print ed.)
Subjects (MeSH)
Drug Therapy, Combination
Dyslipidemias - drug therapy
Abstract
Comprising contributions from leading lipidologists from around the world, this book presents the latest and most comprehensive knowledge on the different options for combination therapy of dyslipidemia, and includes discussion of future therapies that are currently in late stages of clinical evaluation. Dyslipidemia is a leading cause of cardiovascular morbidity and mortality and most patients with this condition fail to achieve adequate control of their serum lipid levels with monotherapy. However, recent US and European guideline recommendations, based on randomized, controlled trials, fail to discuss combination therapy options for patients with dyslipidemia. Statins remain the mainstay of drug therapy for hyperlipidemia and chapters in this book specifically examine the role of add-on therapy with different agents modulating the different lipid fractions in the blood, e.g. bile acid sequestrants, fibric acid derivatives (fibrates), omega-3 fatty acids (fish oils), inhibitors of Niemann-Pick C1 like 1 (NPC1L1) protein, cholesteryl ester transfer protein (CETP), apolipoprotein B-100 and microsomal triglyceride transfer protein (MTP), and the emerging proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitors. There is additional discussion of the role of non-drug therapy options such as nutraceuticals, functional foods and lipoprotein apheresis. The book also discusses the combination of antihypertensive drugs with lipid-lowering drugs in the management of cardiovascular risk in patents with dyslipidemia.
Contents
[publisher supplied] Statins and bile acid resins: is there a place for such a combination? -- Statins and fibrates: should it be recommended? -- Statins and ezetimibe: doubts or bright future? -- Statins and niacin: the end of residual risk therapy? -- Statins and omega-3 fatty acids: what more do we need? -- Statins and CETP inhibitors: anacetrapib and evacetrapib: the last hope? -- Statins and mipomersen: the issue of tolerability? -- Statins and lomitapide: a suitable response for HoFH -- Statins and PCSK9 inhibitors: defining the correct patients -- Other possible drug combination for dyslipidaemia -- Statins and nutraceuticals/functional food: could be they combined? -- Lipid lowering therapy and apheresis: indications and outcomes -- Combination of lipid lowering agents with antihypertensive drugs: a joint fight against the two most important risk factors? -- Not only dyslipidaemia therapy: the time for polypills -- Drug Evaluation: Fenofibrate + simvastatin for the treatment of dyslipidemia: When and for whom? -- Drug Evaluation: Olmesartan medoxomil + rosuvastatin for the treatment of dyslipidemia and concomitant risk factors: A chance for better compliance? -- Conclusions and Take Home Message.
Format
e-Book
Location
Online
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Comprehensive Biochemistry for Dentistry : Textbook for Dental Students

https://libcat.nshealth.ca/en/permalink/provcat44220
Anil Gupta. --Singapore: Springer , 2019.
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Location
Online
This book combines fundamental concepts of biochemistry and the dental sciences to provide an authentic, coherent and comprehensive text for dental students. It describes in simple language the intricate pathophysiology of biomolecules in health and in diseases of dental and oral tissues. This book also describes the evolution of biochemistry in a chronological order, provides information about the fundamental chemical structure, classification and biological significance of biomolecules, vitam…
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Author
Gupta, Anil
Responsibility
Anil Gupta
Place of Publication
Singapore
Publisher
Springer
Date of Publication
2019
Physical Description
1 online resource (xxxv, 604 p.) : 266 illus., 195 illus. in color
ISBN
9789811310355
9789811310348 (Print ed.)
9789811310362 (Print ed.)
Subjects (MeSH)
Biochemical Phenomena
Dentistry - education
Specialty
Biochemistry
Dentistry
Abstract
This book combines fundamental concepts of biochemistry and the dental sciences to provide an authentic, coherent and comprehensive text for dental students. It describes in simple language the intricate pathophysiology of biomolecules in health and in diseases of dental and oral tissues. This book also describes the evolution of biochemistry in a chronological order, provides information about the fundamental chemical structure, classification and biological significance of biomolecules, vitamins and hormones, enriched with flow charts and diagrams for easy understanding and quick reference. It includes chapters on nucleic acids, nutrition and serum enzymes and organ function tests, and offers an innovative approach to familiarize dental students with the biochemical composition of enamel, dentine, cementum and saliva, explaining the biochemical basis of dental caries, periodontal diseases, role of fluorides in caries prophylaxis, fluoride toxicity, and the role of amino acids as anti-hypersensitive agents.
Contents
Introduction to Biochemistry -- Part I. Cellular Biochemistry -- Cell and Organelles -- Part II. Structural Biochemistry -- Proteins and Amino acids -- Plasma Proteins -- Haemoglobin -- Carbohydrates -- Lipids -- Nucleic Acids -- Enzymes -- Hormones -- Vitamins -- Part III. Metabolism -- Digestion and Absorption of Proteins -- Metabolism of Proteins and Amino acids -- Digestion and Absorption of Carbohydrates -- Metabolism of Carbohydrates -- Digestion and Absorption of Lipids -- Metabolism of Lipids -- Metabolism of Minerals -- Biological Oxidation -- Part IV. Medical Biochemistry -- Acid-Base Balance -- Nutrition -- Serum Enzymes and Organ Function Tests -- Part: V Immunochemistry -- Immunoglobulins -- Part V. Dental Biochemistry -- Dental Biochemistry.
Format
e-Book
Location
Online
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