This book presents different patient-oriented perspectives from surgeons, economic evaluation and management researchers, and business companies active in the healthcare sector, striking a balance between the appropriateness/effectiveness of treatment and efficiency/cost. It does not include technical surgical details, but instead provides the necessary knowledge regarding different groups of patients to help economic and management researchers make accurate evaluations. Although partially base…
This salient volume surveys the state of access to primary care and preventive health services by migrants, refugees, and asylum seekers across Europe. Experts in public health and allied fields identify obstacles to healthcare interventions for migrants, including costs, legal status, health-related behaviors and beliefs, and cultural and language barriers. The book includes the latest data concerning access to specific preventive services (e.g., vaccinations, colorectal screenings), specific …
This book provides comprehensive information on the alternative (non-animal) dermal toxicity test methods currently available for industrial, regulatory, and academic use and also explores potential future developments. It encompasses all areas of dermal toxicity, including skin irritation, skin corrosion, skin sensitization, UV-induced effects, and skin genotoxicity. An individual chapter is devoted to each test method, with coverage of the scientific basis, validation status and regulatory ac…
The first edition of this book was judged by many to be the best available atlas of upper gastrointestinal and hepato-pancreato-biliary surgery. The second edition builds upon this success by covering all of the significant intervening developments, including both new procedures and adaptations of established techniques. The atlas opens with an introductory section on the basic principles of operative surgery. All of the important techniques employed in upper gastrointestinal and hepato-pancrea…
In this thesis, a tracking system was developed by modifying an add-on collimator, the Siemens Moduleaf, for realtime applications in radiotherapy. As the add-on collimator works almost completely autonomously of the linear accelerator (LinAc), no modifications to the latter were necessary. The adaptations to the Moduleaf were mainly software-based. In order to reduce the complexity of the system, outdated electronic parts were replaced with newer components where practical. Verification was pe…
Ischemic heart disease is the leading cause of morbidity and mortality in the developed world. The high metabolism and oxygen demand of the cardiac myocardium depends on both a high blood flow and a rich capillary density. For this reason, the growth of the coronary vasculature is vital, not only in early development, but also in the adult faced with various stresses. Novel technologies have enabled the discovery of the molecular mechanisms underlying the growth and assembly coronary vessels, a…
Health care companies want to deliver their services with greater efficiency and cost-effectiveness. Consumers want services that are effective, responsive, convenient, and worth the cost. In response to these demands, web-based and other electronic technologies are revolutionizing health care services. Critical Issues for the Development of Sustainable E-Health Solutions surveys this rapid transformation as it is occurring worldwide. Focusing on new applications in consumer-centered health ca…
This text explores the state-of-the-art effects of exercise on blood pressure among adults with hypertension in addition to many of the possible mechanisms underlying essential hypertension in humans. The book contains chapters by distinguished experts on the effects of exercise on physiological systems known to be involved in hypertension development and maintenance as well as less well known aspects of hypertension such as exercise effects on the 24-hour ambulatory blood pressure profile, and…
Understanding the influence and interaction between physical activity and the endocrine system are of paramount importance in dealing with a multitude of health problems. In Endocrinology of Physical Activity and Sport, renowned physicians and researchers provide a comprehensive and expanded update on the scientific, clinical and practical components of endocrinology as related to sport and exercise. The authors thoroughly review what is known about how such activity affects the endocrine syste…
Now in its fully revised and expanded third edition, this comprehensive text represents a compilation of the critical endocrinology topics in the areas of sports medicine, kinesiology and exercise science, written by leading experts in the field. As in previous editions, the focus here is on the critical issues involved in understanding human endocrinology and hormonal workings with regards to physical activity, exercise and sport and how such workings impact the full range of medical condition…
Providing a comprehensive review of the interactions between exercise and human reproduction, this unique text focuses on both the positive and negative consequences of sport and physical activity on male and female fertility and infertility and the biological mechanisms and processes behind them. Beginning with a review of the structure and function of the male and female reproductive systems as well as fertilization and gestation, the discussion then turns to the physiology and endocrinology …
This book provides an innovative and comprehensive overview of the relationship between lung and exercise, both in healthy, active subjects and in subjects with chronic respiratory diseases. It investigates in detail the central role of the lungs during exercise and illustrates the impact of respiratory impairment due to both acute and chronic lung diseases on performance. Further, the book presents the latest evidence-based findings, which confirm that exercise is an effective and safe form of…
This book provides a comprehensive overview of exercise physiology in patients with congenital heart disease and other pediatric cardiopulmonary disorders. It begins with an in-depth but pragmatic discussion of exercise physiology and the cardiopulmonary adaptations to physical activity, followed by a review of the conduct and interpretation of cardiopulmonary exercise tests. Subsequent chapters discuss exercise physiology and testing in patients with a variety of congenital heart diseases, inc…
This practical guide aids clinicians in distinguishing the different dimensions of hand function such as impairment, disability, and handicap. New and updated chapters discuss cerebral palsy, sports injuries, robotics, and assistive technologies. Extensively revised, the book provides a broad overview of the basic principles and examination of hand function. It describes how to evaluate hand function in specific afflicted populations, including the rheumatoid patient, the stroke patient, the tr…
The world is faced with an epidemic of metabolic diseases such as obesity and type 2 diabetes. This is due to changes in dietary habits and the decrease in physical activity. Exercise is usually part of the prescription, the first line of defense, to prevent or treat metabolic disorders. However, we are still learning how and why exercise provides metabolic benefits in human health. This open access volume focuses on the cellular and molecular pathways that link exercise, muscle biology, hormon…
Advanced therapies and technologies, new service delivery methods, and care upgrades Advanced therapies and technologies, new service delivery methods, and care upgrades in underserved areas are translating into improved quality of life for millions with disabilities. Occupational therapy parallels this progress at the individual level, balancing short-term recovery and adaptation with long-term independence and well-being. This Second Edition of the International Handbook of Occupational Thera…
This book discusses major changes in our understanding of the most prevalent non-orthopedic, sports-related condition – overtraining syndrome (OTS), arguing that it should be considered as the manifestation of burnout in athletes, rather than simply the result of excessive training. While the chronic adaptations of the cardiovascular and musculoskeletal systems to exercise are well documented, those of the endocrine system are less well known, and adaptations of the hormonal ranges for athletes…
Pediatric Neuro-Ophthalmology, 3rd edition provides the single authoritative resource on the pathophysiology, diagnostic evaluation, and treatment of neuro-ophthalmologic disorders in children. This book is encyclopedic in scope, incorporating extensive references for each condition, numerous diagrams and pictures, and a detailed analysis of the clinical disorders included in the differential diagnosis of each condition. The third edition builds upon this format to incorporate new discoveries a…
This second edition of Freemark's text embodies all of the strengths of the original work but is deeper and broader in scope, with new chapters on emerging themes including metabolomics, genomics, and the roles of gastrointestinal hormones, the microbiome, brown adipose tissue, and endocrine disruptors in the pathogenesis of childhood obesity. Reviews of the effects of weight excess on cognitive performance and immune function complement detailed analyses of the biochemical and molecular pathwa…