After introductory chapters devoted to the safe production and distribution of vaccines, the book addresses the question of adult vaccination in the framework of a life-course approach to vaccination. It presents the proceedings of multidisciplinary expert discussions with an excellent summary of the current state of knowledge on adult vaccination in various diseases, as well as an overview of the professionals involved and the obstacles to achieving greater vaccine uptake, and how these may be…
Loco-regional anesthesia presents definite advantages in almost all surgical branches, since it couples a perfect anesthesia with a long postoperative analgesia. This discipline is constantly developing thanks to new drugs and new techniques. In the last decade the advent of ultrasound guided regional anesthesia has extended the study from the anatomic room to the virtual but real "in corpore viri" ecographic image thus increasing the success rate of this type of anesthesia. Together with elect…
This book discusses and explains the importance of biochemistry knowledge in understanding what happens to patients during anesthesia and/or to those being in intensive care. Anesthesiological and intensive care practice require a detailed biochemistry knowledge to avoid onset of complications and/or to deal with unexpected events promptly and appropriately. The book is intended for anesthesiologists, intensivists, anesthesia teachers, anesthesia trainees and residents.
This book is a scientific compendium documenting the state of the art in the discovery and development of vaccines, monoclonal antibodies, and enzymes for the treatment of Substance Use Disorders (SUDs). The book gives detailed consideration to some of the most cutting edge topics in addiction medicine, including vaccines for nicotine, cocaine, heroin, and methamphetamine dependence; monoclonal antibodies against cocaine, methamphetamine, and phencyclidine; and the enzymes butyrylcholinesterase…
This book is an in-depth and user-friendly reference for better understanding immune-mediated skin diseases and their therapies. The focus is on the needs of the physician, resident, or student to understand the pathophysiology of the disease as well as the mechanisms of action of the therapies. Clinical and Basic Immunodermatology, Second Edition is an effective teaching tool that has practical applications for use on a daily basis. It is a valuable resource for practicing dermatologists, derm…
The management of pain can often be achieved by medications, physical therapies, or by various procedural techniques that have evolved in recent decades. With the trend towards more outpatient surgeries and less invasive surgeries to decrease perioperative risk, perioperative time, and costs, the practice of anesthesia is evolving to utilize regional anesthesia techniques both for inpatients and outpatients. Regional anesthesia is being performed for outpatient surgeries, obstetric anesthesia, …
This text encompass an up-to-date, comprehensive review of the state-of-the-art for gland preserving therapies. Fully updated and revised, this text evaluates the scientific evidence for the evolving trend to treat intermediate risk, clinically localized prostate cancer in a focally ablative manner with novel gland-preserving, focal therapy methods. Various ablative devices such as high intensity focused ultrasound, irreversible electroporation, photodynamic therapy, cryotherapy and laser ablat…
This book provides a comprehensive overview of current immunotherapy strategies, and how these may be applicable to childhood cancers. The first part of the book reviews how the immune system recognizes cancer, and the various escape mechanisms allowing tumour growth. The importance of the tumor microenvironment and the challenges this may present to achieving effective immunotherapy are discussed. Monoclonal antibodies, cellular, cytokine and vaccine therapies are all comprehensively reviewed,…
This timely book, published just as cancer immunotherapy comes of age, summarizes the rationale, present status, and future perspective for cancer immunotherapy. Included are explanations of the constitution of the immune system and immunocheckpoints, the mechanism of antigen presentation and recognition, valuable modalities, clinical trials and guidance, personalization, and biomarkers, all of which are essential for understanding the success of cancer immunotherapy. This innovative therapy ha…
This unique text focuses exclusively on the ever-growing population of aging and masters athletes, both professional and amateur, presenting both operative and nonoperative management strategies for the range of sports-related injuries. The book is thematically divided into three sections. Part I describes the science of musculoskeletal aging and the benefits of remaining active as we age, including proper nutrition, supplements and medical therapies and adjuvants. Injuries common to the master…
Elsevier now offers a series of derivative works based on the acclaimed Meyler's Side Effect of Drugs, 15th Edition. These individual volumes are grouped by specialty to benefit the practicing biomedical researcher and/or clinician.
The use of minimally invasive spine surgery (MISS) has grown rapidly over the last decade and remains the fastest growing area in spine surgery. Now in a revised and expanded second edition including 19 new chapters, this comprehensive textbook provides an updated presentation of the field of MISS, highlighting surgical techniques and clinical outcomes as well as providing a unique focus on how these techniques are applied for specific spinal conditions. Minimally Invasive Spine Surgery, Second…