This volume, written by well-known experts in the field, covers all aspects of Anti-Neutrophil Cytoplasmic Antibody (ANCA) Associated Vasculitis (AAV). The expression refers to a group of diseases, characterized by destruction and inflammation of small vessels. The clinical signs vary and affect several organs, such as the kidney, lung, skin, nervous system and others. The opening chapters give some historical hints, explain the genetic basis of the disease and provide insights into the pathoge…
This book provides a practically applicable guide to the use of multimodality imaging for managing aortic valve disorders. Details of how to successfully diagnose a range of aortic valve diseases is presented, with detailed information covered on the techniques and relevant criteria for pre-operative screening, surgical and transcatheter planning, intraprocedural imaging and related postoperative follow-up. Multimodality Imaging for Cardiac Valvular Interventions, Volume 1 Aortic Valve: From Di…
This book is designed as a reference manual that is exceptional in systematically discussing every aspect of nuclear medicine imaging of infections, with careful explanation of the most up-to-date concepts and recent guidelines on diagnostic flowcharts as shared between the EANM, ESR, ESNR, ESCMID, ESC, EACVI, ECCO, ESGAR and EBJIS. It is truly comprehensive, describing all methods, all acquisition parameters, and all interpretation criteria in all infectious diseases. The early chapters discus…
This book, now in a second revised edition, casts light on the often complex diagnosis of musculoskeletal tumors and tumor-like conditions by drawing on the experience of the Rizzoli Orthopedic Institute during more than 100 years of treatment and research in the field. The different entities are described from a multidisciplinary perspective, highlighting clinical, radiological, and histological correlations. Particular emphasis is placed on differential diagnosis, which often needs to take in…
This book offers an overview of the latest advances in the epidemiological, pathophysiological, diagnostic and therapeutic aspects of secondary hypertension, provided by a group of the most highly respected European experts in this field. It is common belief that secondary forms of hypertension are rare, although in 95% of patients the cause of high blood pressure is unknown – euphemistically referred to as “essential”. There is increasing evidence from epidemiological studies that the prevalen…
This book represents a comprehensive, clinically oriented text covering all aspects of male osteoporosis, from the basic concepts of bone physiology and regulation of bone remodeling in men, the causes and pathophysiological mechanisms responsible for the most frequent causes of osteoporosis, to diagnostic and screening protocols, as well as prevention and treatment approaches. It offers a broad overview of male osteoporosis by specialists involved in research and clinical practice and discusse…
This open access book discusses individual, collective, and institutional responsibilities with regard to vaccination from the perspective of philosophy and public health ethics. It addresses the issue of what it means for a collective to be morally responsible for the realisation of herd immunity and what the implications of collective responsibility are for individual and institutional responsibilities. The first chapter introduces some key concepts in the vaccination debate, such as ‘herd im…
This volume describes the most relevant and cutting-edge technological news on the complex surgical procedure of acoustic neuroma. The clinical-radiological diagnosis and surgical indications are briefly presented and the surgical technique is illustrated step-by-step: video clips show the latest means of treating these patients. All these indications were prepared by highly experienced experts in the field, based on their personal experience. The new technologies discussed concern e.g. the int…
This book, featuring a practical hands-on format, describes an up-to-date and comprehensive approach to the management of complex knee injuries. The aim is both to equip practitioners with reliable expert guidance and to foster consensus in a field characterized by continuing debate. Initial response and diagnostic evaluation are explained, surgical techniques appropriate for different injuries are fully documented, and advice is provided on the response to injuries in specific scenarios and pa…
This book encompasses the theoretical and practical aspects of surgical ethics, with a focus on the application of ethical standards to everyday surgical practice and the resolution of ethical conflicts in the surgical arena. It provides surgeons (both prospective and practicing) in the different surgical fields with deep, practical insights into the topic. A 21st century surgeon requires complete competence (superb clinical skills, expert surgical decision-making and outstanding performance an…
This book addresses the fundamental importance of the proper assessment and treatment of sexual disorders in patients with mental disorders with regard to their treatment outcomes and adherence to therapies. In fact, patients with mental disorders often suffer from sexual dysfunctions and in many cases, pharmacological treatment causes sexual-dysfunction side-effects. However, anxiety disorders, personality disorders, eating disorders and psychotic disorders are often also characterized by sexu…
This book offers an up-to-date review on the principles and practice of multidimensional assessment and management of the older individual, which represents the cornerstone of modern clinical practice in the elderly. The early chapters cover the main elements and scope of the comprehensive geriatric approach and explain the pathways of care from screening and case finding through to in-depth assessment and treatment planning. Subsequent chapters review the evidence of how best to apply the mult…
This book provides essential insights into how the approach to nursing care in ICU patients has markedly changed over recent years. It shows how the focus has progressively moved away from the technical approach that characterized early ICUs to a wider personalization of patient care that also highlights general problems such as basic hygiene and general comfort. It also demonstrates that, at the same time, the nurses' role has become more professionalized, with increasing competences in assess…
This book presents, in condensed form, the clinical results achieved by means of various locoregional tumor therapies employed for different indications. In so doing, it will allow the reader to rapidly retrieve the information on indications and effectiveness that is required for optimal integration of these highly effective therapies into modern, complex treatment strategies. The renaissance in locoregional tumor therapies is an ongoing process. New chemotherapeutic schedules, especially for …
This book systematically focuses on central sleep apneas, analyzing their relationship especially with heart failure and discussing recent research results and emerging treatment strategies based on feedback modulation. The opening chapters present historical background information on Cheyne-Stokes respiration (CSR), clarify terminology, and explain the mechanics and chemistry of respiration. Following a description of the physiology of respiration, the pathophysiology underlying central apneas…
This second edition presents the first update on a consensus process during which all evidence from the literature with a survival benefit in the perioperative period was gathered, and in which 500 physicians from 61 countries worked to confirm the findings. Perioperative morbidity and mortality currently represent a public health problem, as mortality alone is 1-4% in Western countries. Surprisingly, randomized evidence of survival benefit in the perioperative period is available for only 12 t…
This book introduces the exciting field of orthobiology, which will usher in a new array of therapeutic approaches that stimulate the body's natural resources to regenerate musculoskeletal tissues damaged by trauma or disease. The book addresses a range of key topics and discusses emerging approaches that promise to offer effective alternatives to traditional treatments for injuries to bone, cartilage, muscles, ligaments, and tendons. It explains in detail how a variety of innovative products, …