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Transplantation of the liver

https://libcat.nshealth.ca/en/permalink/provcat32185
[edited by] Ronald W. Busuttil, Goran B. Klintmalm. (2nd ed.) --Philadelphia, PA: Elsevier Saunders , 2005.
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Spearheaded by two of the world's preeminent experts in liver surgery, the new edition of this landmark masterwork encompasses all of today's best knowledge in the field. It provides detailed discussions of everything from pathophysiology and patient and donor selection...through transplantation anesthesia and full range of operative procedures...to immunosuppression, postoperative care, and ethical issues. The result is an ideal single source for authoritative, up-to-the-minute guidance on eve…
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Other Authors
Busuttil, Ronald W
Klintmalm, Goran B
Responsibility
[edited by] Ronald W. Busuttil, Goran B. Klintmalm
Edition
2nd ed.
Place of Publication
Philadelphia, PA
Publisher
Elsevier Saunders
Date of Publication
2005
Physical Description
1 online resource (xxx, 1485 p.)
ISBN
9781437712964 (electronic bk.)
Subjects (MeSH)
Liver Transplantation
Subjects (LCSH)
Liver - Transplantation
Liver Transplantation
Foie - Greffe
Transplantatie
Lever
Abstract
Spearheaded by two of the world's preeminent experts in liver surgery, the new edition of this landmark masterwork encompasses all of today's best knowledge in the field. It provides detailed discussions of everything from pathophysiology and patient and donor selection...through transplantation anesthesia and full range of operative procedures...to immunosuppression, postoperative care, and ethical issues. The result is an ideal single source for authoritative, up-to-the-minute guidance on every imaginable aspect of liver transplantation. Discusses the background and available management options for each hepatic disease entity. Addresses anesthesia for liver transplantation"oa crucial aspect of successful surgery that is often neglected in other sources. Provides step-by-step descriptions of today's full range of transplantation techniques. Details postoperative care, including intensive Considers the ethical issues involved in using living donors. Delivers pearls and pitfalls that provide important advice from world-renowned experts
Contents
I. General Considerations -- 1.History of Liver and Other Splanchnic Organ Transplantation -- 2.Liver Organ Allocation: The U.S. Model -- 3.Liver Organ Allocation: The Great Britain and European Models -- 4.Hepatic Anatomy -- 5.Hepatic Physiology and Assessment of Hepatic Function -- 6.Molecular Biology of the Liver -- 7.Influence of Liver Transplantation on Liver Surgery -- II. Patient Evaluation: Adult -- 8.Current Indications, Contraindications and Timing for Liver Transplantation -- 9.Transplantation for Viral Hepatitis A & B -- 10.Transplantation for Hepatitis C -- 11.Transplantation for Fulminant Hepatic Failure -- 12.Transplantation for Primary Biliary Cirrhosis -- 13.Transplantation for Sclerosing Cholangitis -- 14.Liver Transplantation for Autoimmune Chronic Active Hepatitis -- 15.Transplantation for Primary Hepatic Malignancy -- 16.Liver Transplantation for Metastatic Hepatic Malignancy -- 17.Liver Transplantation for Hematological Disorders: Hereditary Hemochromatosis, Protophyria, and Coagulation Defects -- 18.Transplantation for Budd-Chiari Syndrome -- 19.Liver Transplantation for Alcoholic Cirrhosis -- 20.Unusual Indications for Liver Transplantation -- III. Patient Evaluation: Pediatric -- 21.General Criteria for Pediatric Transplantation -- 22.Transplantation for Cholestatic Liver Disease -- 23.Transplantation for Biliary Atresia -- 24.Liver Transplantation for Metabolic Disease -- 25.Transplantation for Hepatic Malignancy in Children -- 26.Nutritional Aspects of Pediatric Liver Transplantation -- IV. Special Considerations in Patient Evaluation -- 27.Ethical Decisions in Liver Transplantation -- 28.Psychosocial Assessment of Adult Liver Transplant Recipients -- 29.Pretransplantation Evaluation: Pulmonary, Cardiac, and Renal -- 30.Pretransplantation Infectious Disease Screening for Transplantation Candidates -- 31.Role of the Clinical Nurse Coordinator: Preoperative Care -- 32.Radiologic Evaluation in the Liver Trnaplant Patient -- 33.Monitoring and Care of the Patient Prior to Transplantation -- 34.Nutritional Aspects of Adult Liver Transplantation -- 35.Surgery for Portal Hypertension in the Era of Liver Transplantation -- V. The Operation -- 36.Donor Selection and Management -- 37.The Donor Operation -- 38.Principles of Organ Preservation -- 39.The Recipient Hepatectomy and Grafting -- 40.Anesthesia for Liver Transplantation -- VI. Split and Living Donor Transplantation -- 41.Split Liver Transplantation for the Pediatric and Adult Recipient -- 42.Living Related Liver Transplantation in Pediatric Recipients -- 43.Split Liver Transplantation for Two Adults -- 44.Adult Living Donor and Recipient Evaluation and Selection -- 45.Adult Living Donor Hepatectomy and Recipient Operation -- 46.Imaging Techniques in Living Donor Transplantation -- 47.Outcomes in Living Donor Transplantation -- VII. Unusual Operative Problems -- 48.Venous Anomalies Including Protal Vein Thrombosis and Prior Portosystemic Shunts -- 49.Liver Transplantation and Situs Inversus -- 50.Retransplantation -- 51.Clinical Management of Necrotic Liver During Transplantation Surgery -- 52.Transplantation of the Liver With Digestive Organs -- 53.Combined Liver-Kidney Transplantation -- 54.Auxiliary Transplants -- VIII. Postoperative Care -- 55.Postoperative Intensive Care Management -- 56.Postoperative Intensive Care Management: Children -- 57.Postoperative Care Management: Adults -- 58.Postoperative Care Management: Children -- 59.Renal Failure in the Adult Transplant Recipient -- 60.Graft Failure: Cause, Etiology, Recognition and Treatment -- 61.Technical Problems: Biliary -- 62.Technical Problems: Vascular -- 63.Infections After Liver Transplantation -- 64.Late Onset Complications and Recurrent Non-Malignant Disease -- 65.Neuropsychiatric Outcomes in Liver Transplantation -- 66.Transplantation of the Liver: Postoperative Neurological Disorders and Prognosis -- 67.Role of the Posttransplantation Coordinator -- IX. Liver Transplant Pathology -- 68.Histological Patterns of Rejection and Other Causes of Liver Dysfunction -- 69.Pathology of Recurrence of Non-Neoplastic Disease After Liver Transplantation -- 70.Posttransplantation De Novo Malignancies -- X. Immunology of Liver Transplantation -- 71.Rejection After Transplantation -- 72.Cell Migration, Chimerism, and Graft Acceptance, With Particular Reference To the Liver -- 73.ABO, Tissue Typing, and Crossmatching Incompatibility in Liver Transplantation -- XI. Immunosuppression -- 74.Induction and Maintenance of Immunosuppression -- 75.Special Considerations for Pediatric Immunosuppression After Liver Transplantation -- 76.Treatment of Acute and Chronic Rejection -- 77.New Immunosuppressive Drugs -- XII. Survival and Results -- 78.Preoperative Predictors of Outcome in Liver Transplantation: Models for Defining High-Risk Recipients -- 79.Overall National Results of Liver Transplantation Between 1987 and 2000 -- 80.Long-Term Functional Recovery and Quality of Life -- 81.Results: Survival and Quality of Life After Orthotopic Liver Transplantation in Children -- XIII. Future Developments in Liver Transplantation -- 82.Gene Therapy in Transplantation -- 83.Xenotransplantation -- 84.Hepatocyte Transplantation -- 85.New Approaches in Immunosuppression -- 86.Ischemia Reperfusion Injury of the Liver -- 87.Extracorporeal Xenogeneic Liver Support -- 88.Development of Bio Artificial Liver
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Pathogenesis and Clinical Practice in Gastroenterology

https://libcat.nshealth.ca/en/permalink/provcat40625
edited by I. Ferkolj, A. Gangl, P. R. Galle, B. Vucelic. --Dordrecht: Springer , c2008.
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The translation of new molecular understanding of disease into clinical practice in gastroenterology is a special challenge. The Falk Symposium No. 160, entitled "Pathogenesis and Clinical Practice in Gastroenterology", held 15-16 June 2007 in Portorož, Slovenia, provided a stimulating framework to bridge discussions from bench to bedside. The proceedings of the symposium are contained in this book, and the unifying theme is the growing understanding of inflammation as a driving force in chroni…
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Other Authors
Ferkolj, I
Gangl, A
Galle, P. R
Vucelic, B
Other Authors
Falk Symposium (160th : 2007 : Portorož, Slovenia)
Responsibility
edited by I. Ferkolj, A. Gangl, P. R. Galle, B. Vucelic
Place of Publication
Dordrecht
Publisher
Springer
Date of Publication
c2008
Physical Description
1 online resource (xv, 280 p. : ill.)
Series Vol.
160
Series Title
Falk Symposium
ISBN
9781402087677
9781402087660 (print ed.)
Subjects (MeSH)
Gastrointestinal Diseases - physiopathology
Gastrointestinal Diseases - therapy
Abstract
The translation of new molecular understanding of disease into clinical practice in gastroenterology is a special challenge. The Falk Symposium No. 160, entitled "Pathogenesis and Clinical Practice in Gastroenterology", held 15-16 June 2007 in Portorož, Slovenia, provided a stimulating framework to bridge discussions from bench to bedside. The proceedings of the symposium are contained in this book, and the unifying theme is the growing understanding of inflammation as a driving force in chronic disease leading to disability and malignancy. Aspects of early detection--endoscopically or via molecular markers--are covered as well as in-depth discussions of the validation of new findings in clinical practice. Whilst on a molecular basis gastroenterologists and hepatologists try to shed light on the same intracellular pathways, clinical implications such as surveillance of cancer in IBD or chronic hepatitis with cirrhosis have to be tailored to specific needs. New therapeutic agents--approved or on the horizon of early clinical studies--will dramatically change the options of patients with chronic disease such as Crohn's disease, viral hepatitis or hepatocellular carcinoma.
Contents
Section I. Dysphagia and reflux -- Physiology of swallowing and antireflux mechanisms: anything new from a radiologist's view? -- Oropharyngeal dysphagia, achalasia, and other oesophageal motility problems: clinical relevance and management -- Outcomes of different treatment opproaches for gastro-oesophageal reflux disease -- Barrett's oesophagus: screening, surveillance, treatment: are all questions answered? -- Section II. Helicobacter pylori, NSAID, gastric cancer -- Helicobacter pylori infection: diagnosis, treatment and risks of untreated infection -- Section III. Inflammatory bowel disease section -- Genetics, immunology and biomarkers in clinical practice: do they assist in clinical management? -- Standard therapy for ulcerative colitis and Crohn's disease: the ECCO guidelines -- Biologics, novel therapeutic alternatives in inflammatory bowel disease -- Section IV. Lower gastrointestinal tract (coeliac disease, infection and malignancy) -- Recent advances in coeliac disease -- Gastrointestinal manlfestations of AIDS -- Prevention and screening for colorectal cancer -- Lymphomas of the gastrointestinal tract -- Section V. Clinical challenges in liver diseases -- Do we still need liver biopsies? -- Inflammation and human cancer -- Section VI. Viral hepatitis -- New insights in the immunology of viral hepatitis B and C -- New aspects of treatment of chronic hepatitis C -- Section VII. Metabolic and autoimmune liver injury -- Non-alcoholic steatohepatitis: metabolic syndrome of the liver -- Autoimmune hepatitis -- Immunology of primary biliary cirrhosis and primary sclerosing cholangitis -- Alcoholic hepatitis -- Section VIII. Complications of cirrhosis -- Hepatorenal syndrome in cirrhosis -- Variceal bleeding -- Surveillance and prevention of hepatocellular carcinoma -- Algorithms of diagnosis and options of hepatocellular carcinoma therapy -- Surgical therapy of liver cancer: resection and transplantation.
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Publication Type
Congress
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Massachusetts General Hospital handbook of general hospital psychiatry

https://libcat.nshealth.ca/en/permalink/provcat31595
Theodore A. Stern ... [et al.]. (6th ed.) --Philadelphia: Saunders/Elsevier , c2010.
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Massachusetts General Hospital Handbook of General Hospital Psychiatry, by Theodore A. Stern, Gregory L. Fricchione, Ned H. Cassem, Michael Jellinek, and Jerrold F. Rosenbaum, is your ideal source of guidance on consultation-liaison psychiatry! Experts from the Massachusetts General Hospital-widely respected as one of the world's premier psychiatric institutions-provide practical advice on the diagnosis and treatment of psychiatric issues experienced by in-hospital, medically ill adults and chi…
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Stern, Theodore A
Responsibility
Theodore A. Stern ... [et al.]
Edition
6th ed.
Alternate Title
Handbook of general hospital psychiatry
Place of Publication
Philadelphia
Publisher
Saunders/Elsevier
Date of Publication
c2010
Physical Description
1 online resource (xvii, 729 p.)
ISBN
9781437719277 (electronic bk.)
Subjects (MeSH)
Mental Disorders
Patients - psychology
Psychology, Medical
Referral and Consultation
Subjects (LCSH)
Psychiatric consultation
Patients - Mental health
Sick - Psychology
Mental Disorders
Hospitalization
Patients - psychology
Psychology, Medical
Referral and Consultation
Abstract
Massachusetts General Hospital Handbook of General Hospital Psychiatry, by Theodore A. Stern, Gregory L. Fricchione, Ned H. Cassem, Michael Jellinek, and Jerrold F. Rosenbaum, is your ideal source of guidance on consultation-liaison psychiatry! Experts from the Massachusetts General Hospital-widely respected as one of the world's premier psychiatric institutions-provide practical advice on the diagnosis and treatment of psychiatric issues experienced by in-hospital, medically ill adults and children. This compact resource reads like a handbook, but delivers all the details youd expect from a textbook. Understand and manage the psychological impact of chronic medical problems, life-threatening diseases, disfigurement, and more. Effectively manage difficult patients, including those with hypochondriacal and conversion disorders
Contents
Beginnings: psychosomatic medicine and consultation psychiatry in the general hospital / Thomas P. Hackett ... [et al.] -- Approach to consultation psychiatry: assessment strategies / John Querques and Theodore A. Stern -- The doctor-patient relationship / Christopher Gordon, Margot Philips, and Eugene V. Beresin -- The psychiatric interview / Eugene V. Beresin, Margot Phillips, and Christopher Gordon -- Functional neuroanatomy and the neurologic examination / Anthony P. Weiss and Stephan Heckers -- Limbic music / George B. Murray and Nicholas Kontos -- Psychological and neuropsychological assessment / Mark A. Blais, Sheila M. O'Keefe, and Dennis K. Norman -- Diagnostic rating scales and laboratory tests / Joshua L. Roffman, Benjamin C. Silverman, and Theodore A. Stern -- Mood-disordered patients / Paolo Cassano ... [et al.] -- Delirious patients / Jason P. Caplan ... [et al.] -- Demented patients / William E. Falk and Ilse R. Wiechers -- Psychotic patients / Oliver Freudenreich and Donald C. Goff -- Anxious patients / Mark H. Pollack ... [et al.] -- Alcoholic patients: acute and chronic / Julie D. Ross, David R. Gastfriend, and John A. Renner, Jr. -- Drug-addicted patients / John A. Renner, Jr., Julie D. Ross, and David R. Gastfriend -- Functional somatic symptoms, deception syndromes, and somatoform disorders / Ilana M. Braun ... [et al.] -- Patients with an eating disorder / Anne E. Becker ... [et al.] -- Pain patients / Shamim H. Nejad and Menekse Alpay -- Patients with neurologic conditions I. / Jeff C. Huffman ... [et al.] -- Patients with neurologic conditions II. / Shamim H. Nejad ... [et al.] -- Catatonia, neuroleptic malignant syndrome, and serotonin syndrome / Gregory L. Fricchione ... [et al.] -- Patients with disordered sleep / Patrick Smallwood, Davin K. Quinn, and Theodore A. Stern -- The psychiatric management of patients with cardiac disease / Guy Maytal ... [et al.] -- Sexual disorders and sexual dysfunction / Linda C. Shafer -- Organ failure and transplantation / Owen S. Surman and Laura M. Prager -- Patients with human immunodeficiency virus infection and acquired immunodeficiency syndrome / BJ Beck, Oliver Freudenreich, and Jonathan L. Worth -- Patients with cancer / Ilana M. Braun, William F. Pirl, and Donna B. Greenberg -- Burn patients / Megan Moore Brennan ... [et al.] -- Chronic medical illness and rehabilitation / Guy Maytal ... [et al.] -- Intensive care unit patients / John Querques and Theodore A. Stern -- Genetics and psychiatry / Daniel H. Ebert ... [et al.] -- Coping with illness and psychotherapy of the medically ill / Steven C. Schlozman ... [et al.] -- Electroconculsive therapy in the general hospital / Charles A. Welch, Carlos Fernandez-Robles, and Cristina Cusin -- Psychopharmacology in the medical setting / Jonathan R. Stevens ... [et al.] -- Psychopharmacological management of children and adolescents / Boris A. Lorberg and Jefferson B. Prince -- Behavioral medicine / Brian A. Palmer, Lisa Scharff, and Bruce J. Masek -- Complementary medicine and natural medications / Felicia A. Smith and David Mischoulon -- Difficult patients / Daniel J. Zimmerman and James E. Groves -- Emergency psychiatry / Jennifer M. Park ... [et al.] -- Care of the suicidal patient / Rebecca W. Brendel ... [et al.] -- Care at the end of life / Rebecca W. Brendel -- Pediatric consultation / Brian P. Kurtz, Anna C. Muriel, and Annah N. Abrams -- Consultation to parents with serious medical illness: parenting at a challenging time / Kristin S. Russell and Paula K. Rauch -- Care of the geriatric patient / M. Cornelia Cremens and Ilse R. Wiechers -- Aggressive and impulsive patients / Guy Maytal and Kathy M. Sanders -- Psychiatric illness during pregnancy and the postpartum period / Betty Wang ... [et al.] -- Culture and psychiatry / David C. Henderson -- Legal aspects of consultation / Ronald Schouten and Rebecca W. Brendel -- Collaborative care: psychiatry and primary care / BJ Beck -- Coping with the rigors of psychiatric practice / Abigail L. Donovan, Edward Messner, and Theodore A. Stern -- Billing, documentation, and cost-effectiveness of consultation / Nicholas Kontos, Robert M. Stern, and Theodore A. Stern -- Quality assurance and quality improvement on a psychiatric consultation service / Anthony P. Weiss and Theodore A. Stern -- Psychiatric research in the general hospital / Adrienne O. van Nieuwenhuizen and Dan V. Iosifescu -- Medical psychiatry and its future / Benjamin C. Silverman
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Handbook of Evidence-Based Critical Care

https://libcat.nshealth.ca/en/permalink/provcat40923
Paul Ellis Marik. (2nd edition) --New York, NY: Springer , c2010.
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This updated and revised edition of the classic bedside pocket reference remains the gold standard in critical care medicine. The new edition maintains Dr. Marik's trademark humor and engaging writing style, while adding numerous references to make this book the most current and thorough treatment of evidence-based critical care available. The handbook enables the clinician to find the evidence to support or refute an intervention and to help choose the most appropriate, cost-effective treatmen…
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Author
Marik, Paul Ellis
Responsibility
Paul Ellis Marik
Edition
2nd edition
Place of Publication
New York, NY
Publisher
Springer
Date of Publication
c2010
Physical Description
1 online resource (xiv, 718 p.)
ISBN
9781441959232
9781441959225 (print ed.)
Subjects (MeSH)
Critical Care
Evidence-Based Medicine
Intensive Care Units
Abstract
This updated and revised edition of the classic bedside pocket reference remains the gold standard in critical care medicine. The new edition maintains Dr. Marik's trademark humor and engaging writing style, while adding numerous references to make this book the most current and thorough treatment of evidence-based critical care available. The handbook enables the clinician to find the evidence to support or refute an intervention and to help choose the most appropriate, cost-effective treatment. The analysis of treatment strategies is presented by organ system, and the handbook also covers miscellaneous ICU topics (such as sedation, toxicology, radiology, and sepsis) based on the most frequently found and difficult to solve problems in ICU patient management.
Contents
Introduction to Critical Care Medicine -- Evidence-Based Critical Care -- Classic Critical Care Papers -- Critical Care Medicine 101 -- House Officers Guideline 1: Housekeeping -- Admission-Discharge Criteria -- House Officers Guidelines 2: Procedures -- Chronic Critical Illness -- Fluid Resuscitation and Volume Assessment -- Sedation and Analgesia -- Sepsis -- Catheter-Related Bloodstream Infection -- Antibiotics -- Fever -- Respiratory -- Mechanical Ventilation 101 -- Non-invasive Positive-Pressure Ventilation -- Weaning (Liberation) -- Ventilator-Associated Pneumonia -- Community-Acquired Pneumonia -- ARDS -- Aspiration Pneumonia and Pneumonitis -- Deep Venous Thrombosis-Pulmonary Embolism -- COPD Exacerbation -- Acute Severe Asthma -- Pleural Effusions and Atelectasis -- Cardiac -- Hypertensive Crises -- Acute Coronary Syndromes -- ST Segment Elevation Myocardial Infarction -- Arrhythmias -- Acute Decompensated Cardiac Failure -- Takotsubo Cardiomyopathy -- Gastrointestinal -- Nutrition -- Stress Ulcer Prophylaxis -- Chronic Liver Failure -- Alcoholic Hepatitis -- Fulminant Hepatic Failure -- GI Bleeding -- Pancreatitis -- Diarrhea and Constipation -- Metabolic -- Stress Hyperglycemia and Glycemic Control -- Adrenal Insufficiency and CIRCI -- Hypo- and Hypercalcemia -- Electrolyte Disturbances -- Acid-Base Disturbances -- Acute Renal Failure -- Rhabdomyolysis -- Central Nervous System -- Ischemic Strokes and Intracerebral Hemorrhage -- Delirium -- Seizures and Status Epilepticus -- Management of Raised ICP -- Subarachnoid Hemorrhage -- Miscellaneous ICU Topics -- Anemia and RBC Transfusion -- Coagulopathy and FFP Transfusions -- Thrombocytopenia and Platelet Transfusion -- Eclampsia -- Management Issues in the Elderly -- Management Issues in the Obese Patient -- Multi-organ Dysfunction Syndrome -- Therapeutic Hypothermia -- Toxicology -- Alcohol Withdrawal Syndromes -- Serotonin Syndrome -- Radiology -- PRES -- End-of-Life Issues -- What Defines an Intensive Care Unit? Implications for Organizational Structure -- Intrahospital Transport -- Limiting Errors and Avoiding Litigation -- Avoiding Therapeutic Misadventures in the ICU -- The "Devil's" Medicine Bag -- Words of Wisdom.
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Geriatric Gastroenterology

https://libcat.nshealth.ca/en/permalink/provcat30844
C. S. Pitchumoni, T. S. Dharmarajan, editors. --New York, NY: Springer , c2012.
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As aging trends in the United States and Europe in particular are strongly suggestive of increasingly older society, it would be prudent for health care providers to better prepare for such changes. By including physiology, disease, nutrition, pharmacology, pathology, radiology and other relevant associated topics, Geriatric Gastroenterology fills the void in the literature for a volume devoted specifically to gastrointestinal illness in the elderly. This unique volume includes provision of tr…
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Pitchumoni, C. S
Dharmarajan, T. S
Responsibility
C. S. Pitchumoni, T. S. Dharmarajan, editors
Place of Publication
New York, NY
Publisher
Springer
Date of Publication
c2012
Physical Description
1 online resource (xxi, 690 p. : 208 ill., 113 ill. in color)
ISBN
9781441916235
Subjects (MeSH)
Gastrointestinal Diseases
Subjects (LCSH)
Geriatrics
Gastroenterology
Abstract
As aging trends in the United States and Europe in particular are strongly suggestive of increasingly older society, it would be prudent for health care providers to better prepare for such changes. By including physiology, disease, nutrition, pharmacology, pathology, radiology and other relevant associated topics, Geriatric Gastroenterology fills the void in the literature for a volume devoted specifically to gastrointestinal illness in the elderly. This unique volume includes provision of training for current and future generations of physicians to deal with the health problems of older adults. It will also serve as a comprehensive guide to practicing physicians for ease of reference. Relevant to the geriatric age group, the volume covers epidemiology, physiology of aging, gastrointestinal physiology, pharmacology, radiology, pathology, motility disorders, luminal disorders, hepato-biliary disease, systemic manifestations, neoplastic disorders, gastrointestinal bleeding, cancer and medication related interactions and adverse events, all extremely common in older adults; these are often hard to evaluate and judge, especially considering the complex aging physiology. All have become important components of modern medicine. Special emphasis is be given to nutrition and related disorders. Capsule endoscopy and its utility in the geriatric population is also covered. Presented in simple, easy to read style, the volume includes numerous tables, figures and key points enabling ease of understanding. Chapters on imaging and pathology are profusely illustrated. All chapters are written by specialists and include up to date scientific information. Geriatric Gastroenterology is of great utility to residents in internal medicine, fellows in gastroenterology and geriatric medicine as well as gastroenterologists, geriatricians and practicing physicians including primary care physicians caring for older adults.
Contents
Geriatric Gastroenterology: the Geriatrician's Perspective -- Geriatric Gastroenterology: The gastroenterologist's perspective -- Geriatric gastroenterology: future trends -- The Physiology of Aging -- The Gastrointestinal System and Aging -- Epidemiology of Gastrointestinal disease -- Comprehensive Geriatric Assessment -- Drug effects on the gastrointestinal tract -- Pharmacokinetics of aging -- Drug-nutrient interactions -- Probiotics -- Geriatric Nutritional assessment -- Tube feeding: techniques and procedure -- Enteral and Parenteral nutrition -- Ethical aspects, expectations and outcomes associated with PEG in Dementia -- Water, Potassium, Sodium, and Chloride in Nutrition -- Intravenous Fluid Administration -- B12 and Folic acid -- Iron, copper and zinc -- Vitamin D and calcium -- Dietary Fiber in Health and Disease -- Healthy Diet for the Older adult -- Endoscopy in Older Adults: Risks, benefits, considerations -- Wireless capsule endoscopy -- Gastrointestinal Radiology -- Advanced Imaging of Geriatric Gastrointestinal Pathology -- Laboratory tests in Older Adults: Indications, Interpretations, Issues -- Gastrointestinal Pathology in the Older Adult -- Dysphagia -- Gastroparesis in older adults -- Esophageal Reflux disease and its Complications -- Abdominal pain -- Intestinal Gas -- Constipation -- Diarrhea -- Upper and Lower Gastrointestinal Bleeding -- Liver function tests and interpretation -- Viral Liver Diseases -- Tumors of the liver -- Non-alcoholic Fatty Liver Disease (NAFLD) and Non-alcoholic Steatohepatitis (NASH) -- Drug induced liver injury -- Gall bladder disease -- Acute Pancreatitis -- Chronic Pancreatitis -- Oral health in Older Adults -- Small intestinal bacterial overgrowth syndrome -- Peptic ulcer -- Irritable bowel syndrome -- Intestinal ischemia -- Inflammatory bowel disease -- Non-IBD and Non-Infectious colitis -- Celiac disease -- Diverticular disease -- Clostridium Difficile Associated Diseases -- Gastrointestinal Infections -- Anal Incontinence -- Rectal prolapse -- Colorectal Cancer Screening In The Older Adult: A Case Based Approach -- Gastrointestinal polyps -- Gastric neoplasms -- Esophageal cancer -- Pancreatic cancer -- Colorectal cancer -- Palliative Care of GI issues at the End of Life -- The Surgical Abdomen -- Colostomy and Ileostomy care -- Gastrointestinal and Hepatic Manifestations of Systemic Diseases -- Abdominal aortic aneurysm -- Rheumatological manifestations of Gastrointestinal Disease -- Mucocutaneous manifestations with Gastrointestinal disease -- HIV disease -- Gastrointestinal Disorders in the Older Adult: the Psychiatrist's Role.
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HIV and Liver Disease

https://libcat.nshealth.ca/en/permalink/provcat30847
Kenneth E. Sherman, editor. --New York, NY: Springer , c2012.
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Liver disease has been identified as a leading cause of death in HIV-infected patients since the introduction of highly active antiretroviral therapy (HAART) in 1996. The HIV treatment community has been caught largely unaware of this emerging dilemma. Many HIV care providers are ill-equipped to understand and interpret liver injury patterns, or to provide comprehensive care and management for viral coinfections which they are not familiar with. HIV and Liver Disease provides a comprehensive u…
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Sherman, Kenneth E
Responsibility
Kenneth E. Sherman, editor
Place of Publication
New York, NY
Publisher
Springer
Date of Publication
c2012
Physical Description
1 online resource (xiii, 209 p. : 36 ill., 29 ill. in color)
ISBN
9781441917126
Subjects (MeSH)
Coinfection
HIV infections - complications
Hepatitis, Viral, Human
Liver Diseases - etiology
Subjects (LCSH)
Hepatology
Infectious diseases
Abstract
Liver disease has been identified as a leading cause of death in HIV-infected patients since the introduction of highly active antiretroviral therapy (HAART) in 1996. The HIV treatment community has been caught largely unaware of this emerging dilemma. Many HIV care providers are ill-equipped to understand and interpret liver injury patterns, or to provide comprehensive care and management for viral coinfections which they are not familiar with. HIV and Liver Disease provides a comprehensive update of the field covering the epidemiology, pathogenesis, management and treatment of liver disease in patients with HIV infection. The volume will help HIV care providers understand and interpret liver injury patterns, and/or provide comprehensive care and management for viral coinfections. Gastroenterologists and hepatologists will gain an understanding of complex drug regimens that are used to treat HIV and which may impact HCV and HBV treatment. Written by expert clinicians and researchers across multiple disciplines, HIV and Liver Disease will be of great value to gastroenterologists, hepatologists, infectious disease practitioners, as well as other health care providers who provide care or participate in research in the field of HIV.
Contents
Preface -- The HIV Epidemic in the United States: Current Trends, 2010 -- Epidemiology of Liver Disease in Human Immunodeficiency Virus Infected Persons -- Current and Future Treatment Guidelines for HIV -- Pathology of HIV-Associated Liver Disease -- Non-invasive Markers of Liver Injury and Fibrosis -- Mechanisms of Alcoholic Steatosis/Steatohepatitis -- Immunopathogenesis of Liver Injury -- Host Gene Polymorphisms and Disease/Treatment Outcomes in HIV and Viral Co-infections -- Effects of HIV on Liver Cell Populations -- HIV Replication -- Hepatitis C: Natural History -- Natural History of Hepatitis B Virus in HIV-Infected Patients -- Other Hepatitis Viruses and HIV Infection -- Hepatitis B Virus: Replication, Mutation and Evolution -- Hepatitis C Virus Treatment in HIV -- Treatment of Hepatitis B in HIV-Infected Persons -- Prevention of Hepatitis Infection in HIV-Infected Patients -- Antiretroviral Therapy and Hepatotoxicity -- Management of End-Stage Liver Disease and the Role of Liver Transplantation in HIV infected Patients -- Assessment and Treatment of Alcohol- and Substance-Use Disorders in Patients with HIV Infection -- Racial Disparities in HIV and Liver Disease -- Quality of Life Issues in Patients with HIV and Liver Disease.
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Handbook of Growth and Growth Monitoring in Health and Disease

https://libcat.nshealth.ca/en/permalink/provcat30852
Victor R. Preedy, editor. --New York, NY: Springer , c2012.
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Growth is one of the human body's most intricate processes: each body part or region has its own unique growth patterns. Yet at the individual and population levels, growth patterns are sensitive to adverse conditions, genetic predispositions, and environmental changes. And despite the body's capacity to compensate for these developmental setbacks, the effects may be far-reaching, even life-long. The Handbook of Growth and Growth Monitoring in Health and Disease brings this significant and comp…
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Preedy, Victor R
Responsibility
Victor R. Preedy, editor
Place of Publication
New York, NY
Publisher
Springer
Date of Publication
c2012
Physical Description
1 online resource (clxxi, 3164 p. : 953 ill.)
ISBN
9781441917959
Subjects (MeSH)
Growth and development
Growth Disorders
Human Development
Notes
In 3 volumes, not available separately.
Abstract
Growth is one of the human body's most intricate processes: each body part or region has its own unique growth patterns. Yet at the individual and population levels, growth patterns are sensitive to adverse conditions, genetic predispositions, and environmental changes. And despite the body's capacity to compensate for these developmental setbacks, the effects may be far-reaching, even life-long. The Handbook of Growth and Growth Monitoring in Health and Disease brings this significant and complex field together in one comprehensive volume: impact of adverse variables on growth patterns; issues at different stages of prenatal development, childhood, and adolescence; aspects of catch-up growth, endocrine regulation, and sexual maturation; screening and assessment methods; and international perspectives. Tables and diagrams, applications to other areas of health and disease, and summary points help make the information easier to retain. Together, over 180 self-contained chapters in 15 sections cover every area of human growth, including: Intrauterine growth retardation; Postnatal growth in normal and abnormal situations; Cells and growth of tissues; Sensory growth and development; Effects of disease on growth; Methods and standards for assessment of growth; and more. The Handbook of Growth and Growth Monitoring in Health and Disease is an invaluable addition to the reference libraries of a wide range of health professionals, among them health scientists, physicians, physiologists, nutritionists, dieticians, nurses, public health researchers, epidemiologists, exercise physiologists, and physical therapists. It is also useful to college-level students and faculty in the health disciplines, and to policymakers and health economists.
Contents
SECTION 1. Low and very low birth weight infants -- 1. Development of thyroid function in very low birth weight infants -- 2. Growth after very low birth weights: Germany perspectives -- 3. First trimester fetal growth and low birth weight -- 4. Following up very low birth weight children to preschool age -- 5. Zinc and low birth weight -- 6. Early nutrition and very low birth weights infants -- 7. Aggressive nutritional strategy in very low birth weight infants: impact on growth -- 8. Visual development in very low birth weight infants -- 9. Visual ability in very low birth weight infants -- 10. Parental relationships with very low birth weight infants -- SECTION 2. Intrauterine growth retardation -- 11. Intrauterine growth standards -- 12. Risk factors for adverse outcomes in developing countries: role of interuterine growth retardation -- 13. Growth outcomes in intrauterine growth retardation: Australian perspectives -- 14. Neurodevelopment outcome of children with intrauterine growth retardation: A longitudinal, 10-year prospective study -- 15. Memory functions of children with intrauterine growth restriction -- 16. Intrauterine growth and intelligence -- 17. Drug exposure and intrauterine growth -- 18. Intrauterine growth retardation and non-alcoholic fatty liver disease in children -- 19. Ultrasound brain lesions in intrauterine growth retardation -- 20. Intrauterine growth restriction and blood pressure -- 21. Treatment for Short stature after intrauterine growth retardation -- 22. Anthropometric parameters and intrauterine growth retardation: Togo perspectives -- SECTION 3. Preterm infants -- 23. Periodic breathing in term and preterm infants -- 24. The relationship between growth and perinatal factors in preterm infants -- 25. Growth curves for preterm infants -- 26. Development of oral feeding skills in the preterm infant -- 27. Growth factors and endocrine milieu in preterm and term infants -- 28. Protein metabolism in preterm infants: implications for growth -- 29. Birth weight standards, fetal growth, and preterm infants -- 30. Maturation and growth indices of the brain in preterm infants -- 31. The development of cerebral cortex in prematurely born infants -- 32. Development of motor coordination and attention in preterm infants and relation to intensive care -- 33. Inflammatory and growth mediators in the blood in preterm infants -- 34. Weight gain and linear growth in milk feeding in preterm infants -- 35. Brain volume in preterm infants -- 36. Impact of prematurity on school-age outcomes -- 37. Visual and visuocognitive development in children born very prematurely -- SECTION 4. Postnatal growth in normal and abnormal situations -- 38. Defects on long arm of chromosome 20 and postnatal growth retardation -- 39. Postnatal growth in HIV -- 40. Postnatal growth failure and Z score -- 41. Prediction of postnatal growth curves for premature infants -- 42. Adiposity during preweaning postnatal growth -- 43. Postnatal development in cleft palate -- 44. Blood pressure and postnatal growth in schoolchildren: World and Mexico perspectives -- 45. Hormonal regulation of postnatal growth in children -- 46. Postnatal growth and growth hormone -- 47. Postnatal weight increase and growth velocity of very low birth weight infants: Italian perspectives -- SECTION 5. Catch-up growth -- 48. Weight requirements for Catch-up growth in girls with eating disorders -- 49. Catch-up growth and corticosteroids -- 50. Thyroid function during Catch-up growth -- 51. Endocrine aspects of catch-up growth -- 52. Catch-up growth: Hertfordshire studies -- 53. Catch-up growth up to ten year olds: Dutch perspectives -- 54. Catch-up growth and supine length/height in preterm infants -- 55. Catch-down growth and short-statured parents -- 56. Adiposity and insulin resistance after catch-up growth -- 57. Catch-up and normal growth of children on long-term dialysis -- 58. Lung development in children and in catch-up growth -- 59. Catch-up growth in refugee children -- 60. Failure to achieve catch-up growth: Spanish studies -- 61. Catch-up growth: Mexico perspectives -- 62. Growth surveillance of those without catch-up -- 63. Serum adiponectin levels, insulin resistance, and lipid profile in catch-up and non-catch-up growth -- SECTION 6. Sexual maturation -- 64. Genital development in boys and testosterone levels -- 65. Pesticides and male genital growth -- 66. Pesticides and sexual development in girls -- 67. Disorders of breast growth -- 68. Sexual maturity in slums and rural areas -- 69. Breast development and the environment -- 70. Precocious puberty and growth of breast tissue -- 71. Gonadotropin-suppressive therapy and sexual growth -- 72. Sexual dimorphism and cortisol -- 73. Growth and sexual maturation in psychological disorders -- SECTION 7. Cells and growth of tissues -- 74. Growth and development of the brain -- 75. Growth and development of the kidney -- 76. Growth and development of the intestine -- 77. Growth and development of bone -- 78. Growth and development of muscle -- 79. Growth and development of liver -- 80. Growth and development of heart -- 81. Growth and development of dentofacial tissue -- SECTION 8. Sensory growth and development -- 82. Multisensory reweighting in children -- 83. Motor development in normal children and in disease -- 84. Speech and language development in normal children and in disease -- 85. Visual development -- 86. Development of hearing -- 87. Speech intelligibility development in hearing impaired -- 88. Development of the immune system -- SECTION 9. Country and regional aspects of growth and growth monitoring -- 89. Overview: Child development in developing countries -- 90. Rural versus urban growth in 47 developing countries -- 91. Effect of infant feeding on growth in 20 developing countries -- 92. Field-testing growth standards in different countries -- 93. Breast-feeding and growth in Lebanon -- 94. Features of normal and abnormal growth in India -- 95. Features of normal and abnormal growth in China -- 96. Features of normal and abnormal growth in Brazil -- 97. Features of normal and abnormal growth in Russia -- SECTION 10. Effects of disease on growth -- 98. Impaired bone mineral density in children with cerebral palsy -- 99. Growth in sickle cell disease -- 100. The NIH MRI study of normal brain development in the young -- 101. Minerals and growth: an example with zinc -- 102. Fetal alcohol exposure and infant growth -- 103. Iron deficiency anemia and infant growth -- 104. Growth in children with severe hemophilia -- 105. Growth in autism -- 106. Growth in Down syndrome -- 107. HIV-infected children and growth -- 108. Growth in short bowel syndrome (SBS) -- 109. Child growth and livelihood security -- 110. Growth in cerebral palsy -- 111. Growth in congenital heart disease -- SECTION 11. Exercise, sports, and growth -- 112. Elite sport practice in children: effects on growth -- 113. Effects of gymnastics on growth and pubertal maturation in young girls -- 114. Physical activity and bone growth and development in children -- 115. Child growth in physical activity skill development and dietary modification -- 116. The interaction of exercise, stress, and inflammation on growth -- 117. Growth hormone response to exercise -- 118. Physical activity and bone growth -- 119. Infant mental development index -- SECTION 12. Endocrine Control and Regulation of Growth -- 120. Growth deceleration and corticosteroids -- 121. Leptin and ghrelin in growth -- 122. Insulin-like growth factor and growth -- 123. Adiponectin and growth -- 124. Thyroid hormones and growth -- 125. Growth hormone and child growth -- 126. Growth hormone, Prader-Willi syndrome, and growth -- SECTION 13. Assessment of Growth -- 127. The 2006 WHO Child Growth Standards -- 128. WHO Child Growth Standards and the CDC 2000 growth charts -- 129. International growth standards for school-aged children and adolescents -- 130. Infant growth modeling and assessment of growth -- 131. Use of weight, height, and body mass index to indicate growth failure -- 132. Assessment of psychomotor development and growth -- 133. Growth and development in developing countries: what standards? -- 134. Use of MRI to monitor brain growth -- 135. Neonatal screening methods -- 136. False positives and sensitivity in growth monitoring -- 137. Z scores: what they are and how to use them -- 138. Percentiles: what they are and how to use them -- 139. Growth velocity curves: what they are and how to use them -- 140. Physical activity measured by accelerometry: completing growth evaluations.
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e-Book
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Alcohol, nutrition, and health consequences

https://libcat.nshealth.ca/en/permalink/provcat32449
Ronald Ross Watson, Victor R. Preedy, Sherma Zibadi, editors. --New York, NY: Humana Press , c2013.
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Alcohol, Nutrition, and Health Consequences provides practical, data-driven resources to help the reader understand the basics, treatments and preventive strategies that are involved in the understanding of how alcohol may affect healthy individuals as well as those with chronic alcohol use with or without relevant infectious diseases, obesity, diabetes and/or neurocognitive declines. It will also help the clinician define the causes and types of nutritional changes due to alcohol use and also …
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Other Authors
Watson, Ronald Ross
Preedy, Victor R
Zibadi, Sherma
Responsibility
Ronald Ross Watson, Victor R. Preedy, Sherma Zibadi, editors
Place of Publication
New York, NY
Publisher
Humana Press
Date of Publication
c2013
Physical Description
1 online resource (xxi, 578 p. : 70 ill., 8 ill. in color)
Series
Nutrition and Health
Series Title
Nutrition and health (Totowa, N.J.)
ISBN
9781627030472
Subjects (MeSH)
Alcohol-Related Disorders - complications
Ethanol - adverse effects
Ethanol - metabolism
Nutrition Disorders - etiology
Nutritional Physiological Phenomena
Subjects (LCSH)
Nutrition
Personal health and hygiene
Emergency medicine
Abstract
Alcohol, Nutrition, and Health Consequences provides practical, data-driven resources to help the reader understand the basics, treatments and preventive strategies that are involved in the understanding of how alcohol may affect healthy individuals as well as those with chronic alcohol use with or without relevant infectious diseases, obesity, diabetes and/or neurocognitive declines. It will also help the clinician define the causes and types of nutritional changes due to alcohol use and also explain how nutrition can be used to ameliorate its consequences. Chapters present the application of current nutritional knowledge by physicians and dietitians. Specific areas involving alcohol-related damage due to nutritional changes are reviewed, including heart disease, obesity, digestive tract cancers, lactation, brain function, and liver disease. In addition, alcohol's effects on absorption of minerals and nutrients, a key role in causing damage are treated. The importance of diet in modifying alcohol and its metabolite damage is also explained. Alcohol, Nutrition, and Health Consequences is essential reading for alcohol therapists and researchers as well as primary care physicians and dietitians and is an easy reference to help the clinician, student, and dietitian comprehend the complex changes caused by direct and indirect effects of ethanol at the cellular level via its nutritional modification.
Contents
Alcoholic and Nutrition: an Overview -- Genetics of alcohol metabolism -- Laboratory models available to study alcohol and nutrition -- Ethanol-induced lipid peroxidation and apoptosis in embryopathy -- Alcohol Use During Lactation: Effects on the Mother Infant Dyad -- Moderate alcohol administration: oxidative stress and nutritional status -- Alcohol use and abuse: Effects on Body Weight and body composition -- Alcohol Nutrition and health inequalities -- The effect of diet on protein modification by ethanol metabolites -- Vitamin B12 deficiency in alcoholics -- Alcohol American Indians/Alaskan Natives and Alcohol: Biology, Nutrition and Positive Programs -- Metabolism of Ethanol to Acetaldehyde in the Rat Mammary Tissue. Inhibitory Effects of Plant Polyphenols and Folic Acid -- Dietary zinc supplementation and prenatal ethanol exposure -- Tocotrienol and cognitive dysfunction induced by alcohol -- Soy Products Affecting Alcohol Absorption and Metabolism -- Oats supplementation and alcohol-induced oxidative tissue damage -- Fish oil n-3 fatty acids to prevent hippocampus and cognitive dysfunction in experimental alcoholism -- Alcohol in HIV and possible interactions with antiretroviral medications -- Popular energy drinks and alcohol -- The psychological synergistic effects of alcohol and caffeine -- Alcohol and Smoking: A correlation of use in youth? -- Are there Physiological Correlations between alcohol and tobacco use in adults? -- Alcohol, HIV/AIDS and Liver Disease -- Nutritional status, socioeconomic factors, alcohol and cataracts -- Alcohol Intake and High Blood Pressure -- Alcohol and dyslipidemia -- Dietary antioxidants in chronic alcoholic pancreatitis -- Alcohol consumption, lifestyle factors and risk of type 2 diabetes -- Alcohol, overweight, and obesity -- Nutrition alcohol and anorectic and bulimic adolescents -- Viral infections and cancer during alcohol use -- Ethanol and hepatocarcinogenesis -- Alcohol, diet and their interaction in colorectal and urinary tract tumors -- Alcohol, acetaldehyde and digestive tract cancer -- Alcohol Intake and Esophageal Cancer: Epidemiologic Evidence -- A Nutritional approach to prevent alcoholic liver disease -- Nutraceutical potential of indigenous plant foods and herbs for treatment of alcohol related Liver damage -- Alcohol and nutrition as risk factors for chronic liver disease -- Alcohol-related liver disease: Roles of insulin resistance, lipotoxic ceramide accumulation and endoplasmic reticulum stress -- Nutrition and alcoholic and non-alcoholic fatty liver disease: The significance of cholesterol -- Dietary fatty acids and alcoholic liver disease -- Nutrition in alcoholic steatohepatitis -- Alcoholic and non-alcoholic fatty liver disease and vitamin A.
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e-Book
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Online
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Alcohol use disorders and the lung : a clinical and pathophysiological approach

https://libcat.nshealth.ca/en/permalink/provcat33180
edited by David M. Guidot, Ashish J. Mehta. --New York, NY: Humana Press , c2014.
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Alcohol Use Disorders and the Lung: A Clinical and Pathophysiological Approach is an excellent resource for clinicians who care for individuals affected by alcohol use disorders in diverse settings. Although alcohol abuse alone does not cause acute lung injury, it renders the lung susceptible to dysfunction in response to the inflammatory stresses of sepsis, trauma, and other clinical conditions recognized to cause acute lung injury. In parallel, these same pathophysiological effects of alcoho…
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Other Authors
Guidot, David M
Mehta, Ashish J
Responsibility
edited by David M. Guidot, Ashish J. Mehta
Place of Publication
New York, NY
Publisher
Humana Press
Date of Publication
c2014
Physical Description
1 online resource (x, 252 p.)
Series Vol.
14
Series Title
Respiratory medicine (New York, N.Y.)
ISBN
9781461488330 (electronic bk.)
Subjects (MeSH)
Alcohol Drinking - adverse effects
Alcohol-Related Disorders - complications
Lung Diseases
Subjects (LCSH)
Alcohol - Physiological effect
Alcoholism - Complications
Lungs - Diseases
Abstract
Alcohol Use Disorders and the Lung: A Clinical and Pathophysiological Approach is an excellent resource for clinicians who care for individuals affected by alcohol use disorders in diverse settings. Although alcohol abuse alone does not cause acute lung injury, it renders the lung susceptible to dysfunction in response to the inflammatory stresses of sepsis, trauma, and other clinical conditions recognized to cause acute lung injury. In parallel, these same pathophysiological effects of alcohol abuse significantly increase the risk of a wide range of serious lung infections. Many clinicians involved in the primary treatment of alcohol use disorders, such as addiction psychiatrists, will find this text of interest as it will expand their understanding of the health consequences of alcohol use disorders. In parallel, clinicians who specialize in pulmonary and/or critical care medicine will have a unique resource that provides a comprehensive review of the pathophysiology of alcohol-related lung disorders and insights into evolving therapeutic options in these vulnerable individuals. Alcohol Use Disorders and the Lung: A Clinical and Pathophysiological Approach fills a gap in the literature and presents the evolving clinical research that may soon lead to novel therapies that can improve lung health in individuals with alcohol use disorders and co-existing conditions such as HIV infection.
Contents
A Brief History of Alcohol Use and Abuse in Human History -- Overview of the Evolving Recognition of the Health Effects of Excessive Alcohol Use Over the Past Two Centuries Including the Classic Citations -- Current Definitions of Alcohol Use Disorders and the Use of Validated Questionnaires in Clinical Practice and Research -- The Epidemiology of Alcohol Abuse and Pneumonia -- The Epidemiology of Alcohol and Acute Respiratory Distress Syndrome -- Alcohol, the Upper Airway, and Mucociliary Dysfunction in the Conducting Airways -- Alcohol and the Alveolar Macrophage -- Alcohol and the Alveolar Epithelium -- Alcohol-Mediated Oxidative Stress in the Airway: The Unique Role of Thiol Depletion -- Alcohol and the Adaptive Immune Response in the Airway: Dendritic Cell and Lymphocyte Impairments -- Alcohol Impairment of Granulocyte Function During Lung Infection -- Disruption in the Dynamic Balance Between Transforming Growth Factor- and Granulocyte/Macrophage Colony-stimulating Factor Signaling within the Alveolar Space of the Alcoholic Lung: Impact on Epithelial and Macrophage Function -- Alcohol-mediated Zinc Deficiency within the Alveolar Space: A Potential Fundamental Mechanism Underlying Oxidative Stress and Cellular Dysfunction in the Alcoholic Lung -- The Impact of Alcohol Abuse on Multiple Organ Dysfunction in the Surgical Patient -- Alcohol and HIV: Experimental and Clinical Evidence of Combined Impact on the Lung -- Maternal Alcohol Use and the Neonate.
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e-Book
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Online
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Liver immunology : principles and practice

https://libcat.nshealth.ca/en/permalink/provcat33245
M. Eric Gershwin, John M. Vierling and Michael P. Manns, editors. (Second edition) --New York: Springer , c2014.
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Liver Immunology: Principles and Practice, Second Editionbegins with important information about the epidemiology and mortality of liver disease worldwide. This information is followed by chapters related to basic immunology, application of liver immunology for diagnosis, and several excellent chapters thatprovide a solid foundation for understanding immune-mediated liver disease, including those associated with the biliary tree. A chapter on non-hepatic manifestations of immune mediatedliver d…
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Other Authors
Gershwin, M. Eric
Vierling, John M
Manns, Michael P
Responsibility
M. Eric Gershwin, John M. Vierling and Michael P. Manns, editors
Edition
Second edition
Place of Publication
New York
Publisher
Springer
Date of Publication
c2014
Physical Description
1 online resource (xvi, 480 pages)
ISBN
9783319020969 (electronic bk.)
9783319020952
Subjects (MeSH)
Autoimmunity - immunology
Liver Diseases - immunology
Liver - immunology
Liver - pathology
Subjects (LCSH)
Liver - Diseases - Immunological aspects
Liver - Immunology
Médecine
Immunologie
Leber
Abstract
Liver Immunology: Principles and Practice, Second Editionbegins with important information about the epidemiology and mortality of liver disease worldwide. This information is followed by chapters related to basic immunology, application of liver immunology for diagnosis, and several excellent chapters thatprovide a solid foundation for understanding immune-mediated liver disease, including those associated with the biliary tree. A chapter on non-hepatic manifestations of immune mediatedliver disease helps provide context for how these diseases affect the patient overall. In addition, chapters discuss various discrete immunologically-mediated infectious liver disorders including those related to bacteria, parasites, and all of the classic viruses. Chapters on the traditional autoimmune liver diseases -- primary biliary cirrhosis, autoimmune hepatitis, primary sclerosing cholangitis as well as overlap syndrome are also included. The breadth of this comprehensive second edition is highlighted by chapters on alcoholic liver disease, non-alcoholic fatty liver disease, and drug-induced liver disease, among others. This invaluable new edition ends with a forward-looking view of future directions and how the field might meet the challenge of refractory patients. Developed by a renowned group of authors, Liver Immunology: Principles and Practice, Second Editionwill again serve as a comprehensive textbook by providing an excellent overview for this rapidly evolving field. It greatly adds to the understanding of the pathogenesis of these diseases, while also providing novel insights that can be harnessed into helping improve the care of patients afflicted with various immune-mediated diseases. This volume will again be a must-read for clinicians at all levels, investigators and students.
Contents
Introduction -- Core Concepts in Immunology -- The Geoepidemiology of Autoimmune Liver Disease -- Diagnostic Liver Immunology -- The Liver as a Lymphoid Organ -- Innate Immunity and Disorders of the Liver -- The Liver and Immune Tolerance -- The Diagnosis and Classification of Immune-Mediated Hepatic Diseases -- The Diagnosis and Classification of Immune-Mediated Biliary Diseases -- Bacterial Infections in Liver -- The Diagnosis and Classification of Parasitic Diseases of the Liver -- The Diagnosis and Classification of Parasitic Diseases of the Liver -- Viral Diseases of the Liver -- Hepatitis A: Immune Response and Virus Evolution -- Immunopathogenesis of Chronic Hepatitis B and the Clinical Events That Shape its Natural History -- Hepatitis C -- Immunopathogenesis of Hepatitis D -- Hepatitis E -- Primary Biliary Cirrhosis -- Autoimmune Hepatitis -- Primary Sclerosing Cholangitis (PSC) -- Overlap Syndromes -- Alcoholic Liver Disease -- Nonalcoholic Fatty Liver Disease -- Paediatric Liver Disease -- Mechanisms of Acute Liver Failure -- Nonimmune-Mediated Drug-Induced Hepatotoxicity -- Immune-Mediated Drug-Induced Liver Injury -- The Immunopathogenesis of Cirrhosis -- Graft-Versus-Host Disease -- Immune-Mediated Liver Disease in the Transplanted Liver -- The Future of Liver Immunology.
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e-Book
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Online
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Neuromuscular Disorders in Clinical Practice

https://libcat.nshealth.ca/en/permalink/provcat39578
Bashar Katirji, Henry J. Kaminski, Robert L. Ruff, editors. (Second edition) --New York, NY: Springer , c2014.
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Comprehensive, thoroughly updated, and expanded, Neuromuscular Disorders in Clinical Practice, Second Edition encompasses all disorders of the peripheral nervous system, covering all aspects of neuromuscular diseases from diagnosis to treatment. Mirroring the first book, this two-volume edition is divided into two parts. Part one discusses the approach to neuromuscular disorders, covering principles and basics, neuromuscular investigations, and assessment and treatment of neurological disorders…
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Other Authors
Katirji, Bashar
Kaminski, Henry J
Ruff, Robert L
Responsibility
Bashar Katirji, Henry J. Kaminski, Robert L. Ruff, editors
Edition
Second edition
Place of Publication
New York, NY
Publisher
Springer
Date of Publication
c2014
Physical Description
1 online resource (xxv, 1565 p. : 476 illus., 113 illus. in color)
ISBN
9781461465676
9781461465669 (print ed.)
Subjects (MeSH)
Neuromuscular Diseases
Abstract
Comprehensive, thoroughly updated, and expanded, Neuromuscular Disorders in Clinical Practice, Second Edition encompasses all disorders of the peripheral nervous system, covering all aspects of neuromuscular diseases from diagnosis to treatment. Mirroring the first book, this two-volume edition is divided into two parts. Part one discusses the approach to neuromuscular disorders, covering principles and basics, neuromuscular investigations, and assessment and treatment of neurological disorders. Part two then addresses the complete range of specific neuromuscular diseases: neuronopathies, peripheral neuropathies, neuromuscular junction disorders, muscle ion channel disorders, myopathies, and miscellaneous neuromuscular disorders and syndromes. Neuromuscular Disorders in Clinical Practice, Second Edition is intended to serve as a comprehensive text for both novice and experienced practitioners. General neurologists as well as specialists in neuromuscular medicine and trainees in neuromuscular medicine, clinical neurophysiology and electromyography should find this book inclusive, comprehensive, practical and highly clinically focused. Additionally, specialists in physical medicine and rehabilitation, rheumatology, neurosurgery, and orthopedics will find the book of great value in their practice.
Contents
Clinical Assessment in Neuromuscular Disorders -- Nerve and Muscle: Basic Concepts -- Serum Muscle Enzymes in Neuromuscular Disease -- Autoantibody Testing in Peripheral Neuropathy -- Autoantibody Testing of Autoimmune Neuromuscular Junction, Hyperexcitability, and Muscle Disorders -- Forearm Exercise Testing -- Clinical Electromyography (Nerve Conduction Studies and Needle Electromyography) -- Single Fiber EMG -- Quantative EMG Analysis -- Testing of Autonomic Function -- Quantitative sensory testing -- Nerve and Muscle Biopsies -- Skin Biopsy -- Molecular Diagnosis & Genetic Testing -- Outcome Measures and Clinical Assessment Instruments in Neuromuscular Disease -- Physical Management of Patients with Neuromuscular Diseases -- Immunotherapy in the treatment of Autoimmune Neuromuscular Diseases -- Critical and Respiratory Care in Neuromuscular Disorders -- Poliomyelitis and Postpoliomyelitis Syndrome -- Amyotrophic Lateral Sclerosis -- Spinal Muscular Atrophies -- Atypical Motor Neuron Disorders -- Dorsal Root Ganglion Disorders -- Approach to Peripheral Nerve Disorders -- Approach to Small Fiber Neuropathy -- Charcot-Marie Tooth Diseases -- Inherited Metabolic Neuropathies -- Guillian-Barre Syndrome and Related Disorders -- Chronic Inflammatory Demyelinating Polyradiculneuropathy and Related Disorders -- Dysproteinemic Neuropathies -- Diabetic Neuropathies -- Nutritional and Alcoholic Neuropathies -- Metabolic and Endocrine Neuropathies -- Environmental Toxic Neuropathies -- Drug-Induced Toxic Neuropathies -- Vasculitic Neuropathies and Neuropathies of Connective Tissue Disorder -- Vasculitic Neuropathies and Neuropathies of Connective Tissue Diseases -- Infectious and Granulomatous Peripheral Neuropathies -- Peripheral Nerve Injury -- Compressive and Entrapment Neuropathies of the Upper Extremities -- Compressive and Entrapment Mononeuropathies of the Lower Extremity -- Cranial Nerve Palsies -- Peripheral Nerve Tumors -- Cervical Radiculopathy -- Lumbosacral and Thoracic Radiculopathies -- Brachial Plexopathies -- Lumbosacral Plexopathies -- Myasthenia Gravis -- Lambert-Eaton Myasthenic Syndrome -- Botulism -- Congenital Myasthenic Syndromes -- Toxic Neuromuscular Transmission Disorders -- Disorders of Skeletal Muscle Membrane Excitability: Myotonia Congenita, Paramyotonia Congenita, Periodic Paralysis and Related Syndromes -- Malignant Hypothermia -- Approach to Myopathies -- Dystrophinopathies -- Limb Girdle Muscular Dystrophies -- Facioscapulohumeral Muscular Dystrophy -- The Myotonic Dystrophies -- Oculopharyngeal Muscular Dystrophy -- Emery-Dreifuss Muscular Dystrophy -- Congenital Myopathies -- Metabolic Myopathies -- Mitochondrial Myopathies -- Inflammatory Myopathies -- Paraspinous Myopathies: The Dropped Head and Bent Spine Syndromes -- Endocrine Myopathies -- Toxic Myopathies -- Infectious and Granulomatous Myopathies -- Myokymia and Neuromyotonia -- Muscle Cramps and Fasciculations -- Stiff Man Syndrome -- Tetanus -- Neuropletic Malignant Syndrome -- Paraneoplastic Neuromuscular Disorders -- Acute Neuromuscular Weakness in the Intensive Care Unit -- Floppy Infant -- Rhabdomyolyis and Myoglobinuria -- Eosinophilia-Myalgia Syndrome, Eosinophilic Fasciitis, and Related Fasciitis Disorders -- Neuropathic Pain and other Chronic Musculoskeletal Pain Conditions.
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e-Book
Location
Online
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Advances in Nutrition and Cancer

https://libcat.nshealth.ca/en/permalink/provcat39632
Vincenzo Zappia, Salvatore Panico, Gian Luigi Russo, Alfredo Budillon, Fulvio Della Ragione, editors. --Berlin, Heidelberg: Springer , c2014.
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This book comprises proceedings from the Third International Conference on Advances in Nutrition and Cancer, held in Naples in May 2012. This highly multidisciplinary meeting analyzed "nutrition and cancer" from different perspectives and on the basis of distinct and up-to-date experimental approaches. Knowledge on the relation between lifestyle, diet, and cancer is explored in a number of contributions, and the role of dietary intervention in cancer patients is discussed. Issues of vital inter…
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Other Authors
Zappia, Vincenzo
Panico, Salvatore
Russo, Gian Luigi
Budillon, Alfredo
Della Ragione, Fulvio
Other Authors
International Conference on Advances in Nutrition and Cancer (3rd : 2012 : Naples, Italy)
Responsibility
Vincenzo Zappia, Salvatore Panico, Gian Luigi Russo, Alfredo Budillon, Fulvio Della Ragione, editors
Place of Publication
Berlin, Heidelberg
Publisher
Springer
Date of Publication
c2014
Physical Description
1 online resource (xiv, 460 p. : 59 illus., 34 illus. in color)
Series Vol.
159
Series Title
Cancer treatment and research
ISBN
9783642380075
9783642380068 (print ed.)
ISSN
0927-3042
Subjects (MeSH)
Feeding Behavior
Neoplasms - diet therapy
Neoplasms - etiology
Neoplasms - prevention & control
Abstract
This book comprises proceedings from the Third International Conference on Advances in Nutrition and Cancer, held in Naples in May 2012. This highly multidisciplinary meeting analyzed "nutrition and cancer" from different perspectives and on the basis of distinct and up-to-date experimental approaches. Knowledge on the relation between lifestyle, diet, and cancer is explored in a number of contributions, and the role of dietary intervention in cancer patients is discussed. Issues of vital interest to the research community, such as epidemiological and experimental oncology (genetics, epigenetics, and the mechanisms of action of natural compounds in the diet), receive detailed consideration. A further key topic is the emerging molecular technologies (the "omics") that can cast light on the interplay between nutrition and human malignancies. Chapters take the form of reviews that include sections presenting expert opinions. Advances in Nutrition and Cancer will be an invaluable source of topical information for all researchers and clinicians with an interest in this field.
Contents
Part I: Life Style, Diet and Cancer -- The role of metabolic carcinogenesis in cancer causation and prevention: evidence from the European prospective investigation into cancer and nutrition -- Obesity, energy balance and cancer: a mechanistic perspective -- Fruits and vegetables. Updating the epidemiologic evidence for the WCRF-AICR lifestyle recommendations for cancer prevention -- The diet as a cause of human prostate cancer -- Mediterranean dietary pattern and chronic diseases -- Dietary salt intake and risk of gastric cancer -- Alcoholic beverages and carbonated soft drinks: consumption and gastrointestinal cancer risks -- Part II: Natural Dietary Molecules -- Anti-inflammatory and anti-cancer drugs from nature -- Selenium and cancer: a story that should not be forgotten--Insights from genomics -- Resveratrol: from basic studies to bedside -- Quercetin: a pleiotropic kinase inhibitor against cancer -- Sulforaphane as a promising molecule for fighting cancer -- Part III: Genetics and Epigenetics -- Functions, aberrations and advances for chromatin modulation in cancer -- Epigenetics and epidemiology: models of study and examples -- Dietary epigenetics in cancer and aging -- Breast cancer and the importance of early life nutrition -- Part IV: Olive Oil in Cancer Prevention -- Olive oil and other dietary lipids in breast cancer -- A holistic approach to study the effects of natural antioxidants on inflammation and liver cancer -- Extra virgin olive oil: from composition to "molecular gastronomy" -- Part V: Life Style Prevention of Cancer -- Life style prevention of cancer recurrence: the yin and the yang -- Part VI: Emerging Breakthroughs -- New perspective for an old antidiabetic drug: metformin as anticancer agent -- Gut microbes, diet and cancer -- Inflammatory angiogenesis and the tumor microenvironment as targets for cancer therapy and prevention -- Nutriomes and personalised nutrition for DNA damage prevention, telomere integrity maintenance and cancer growth control -- Novel approaches in melanoma prevention and therapy -- Concluding remarks.
Format
e-Book
Publication Type
Congress
Location
Online
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GI/liver secrets plus

https://libcat.nshealth.ca/en/permalink/provcat33473
[edited by] Peter R. McNally. (5th ed.) --Philadelphia, PA: Elsevier Saunders , c2015.
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Stay up to date on today's most common GI and liver disorders and their management with GI/Liver Secrets Plus. This enhanced medical reference book is an excellent resource for understanding the physiology and therapy in hepatic and digestive disease. Whether preparing for an exam or quickly checking a clinical question, the user-friendly Secrets Series® style makes this book a valuable addition to your library.
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Other Authors
McNally, Peter R
Responsibility
[edited by] Peter R. McNally
Edition
5th ed.
Place of Publication
Philadelphia, PA
Publisher
Elsevier Saunders
Date of Publication
c2015
Physical Description
1 online resource, 688 p.
Series Title
Secrets series
ISBN
9780323315777
Subjects (MeSH)
Gastrointestinal Diseases - Examination Questions
Liver Diseases - Examination Questions
Subjects (LCSH)
Digestive organs - Diseases - Examinations, questions, etc
Gastrointestinal Diseases - Examination Questions
Liver Diseases - Examination Questions
Abstract
Stay up to date on today's most common GI and liver disorders and their management with GI/Liver Secrets Plus. This enhanced medical reference book is an excellent resource for understanding the physiology and therapy in hepatic and digestive disease. Whether preparing for an exam or quickly checking a clinical question, the user-friendly Secrets Series® style makes this book a valuable addition to your library.
Contents
Swallowing disorders and dysphagia -- Gastroesophageal reflux disease -- Esophageal causes of chest pain -- Achalasia -- Esophageal cancer -- Esophageal anomalies, infections, and nonacid injuries -- Barrett's esophagus -- Esophageal and stomach pathology -- Gastritis, peptic ulcer disease, NSAIDs, and Helicobacter pylori infection -- Gastric cancer -- Thickened gastric folds -- Gastroparesis -- Evaluation of abnormal liver tests -- General concepts on viral hepatitis -- Antiviral therapy for hepatitis C -- Antiviral therapy for hepatitis B -- Autoimmune hepatitis : diagnosis -- Autoimmune hepatitis : treatment -- Primary biliary cirrhosis and primary sclerosing cholangitis -- Vaccinations and immunoprophylaxis in gastrointestinal and liver disorders -- Pregnancy and liver disease -- Rheumatologic manifestations of hepatobiliary diseases -- Evaluation of focal liver masses -- Drug-induced liver disease -- Alcoholic liver disease, alcoholism, and alcohol withdrawal syndrome -- Vascular liver disease -- Nonalcoholic fatty liver disease and nonalcoholic steatohepatitis -- Liver transplantation -- Ascites -- Liver abscess -- Inheritable forms of liver disease -- Liver histopathology -- Hepatobiliary cystic disease -- Gallbladder disease : stones, crystals, and sludge -- ERCP plus sphincter of Oddi dysfunction -- Acute pancreatitis -- Chronic pancreatitis -- Pancreatic cancer -- Cystic lesions of the pancreas -- Celiac disease -- Crohn's disease -- Ulcerative colitis -- Eosinophilic gastrointestinal disease and eosinophilic esophagitis -- Small intestinal bacterial overgrowth -- Colon disorders and colon cancer -- Constipation and fecal incontinence -- Diverticulitis -- Diseases of the appendix -- Colitis : pseudomembranous, microscopic, and radiation -- Upper gastrointestinal hemorrhage -- Lower gastrointestinal tract bleeding -- Occult and obscure gastrointestinal bleeding -- Evaluation of acute abdominal pain -- Evaluation of acute infectious diarrhea -- Chronic diarrhea -- Aids and the gastrointestinal tract -- Ischemic bowel disease -- Nutrition, malnutrition, and probiotics -- Small bowel and colon pathology -- Foreign bodies and the gastrointestinal tract -- Functional gastrointestinal disorders and irritable bowel -- Endoscopic cancer screening and surveillance -- Rheumatologic manifestations of gastrointestinal diseases -- Dermatologic manifestations of gastrointestinal disease -- Endocrine aspects of gastrointestinal system -- Plain film, barium, and virtual radiography -- Interventional radiology I : cross-sectional imaging procedures -- Interventional radiology II : fluoroscopic and angiographic procedures -- Noninvasive GI imaging : ultrasound, computed tomography, and magnetic resonance imaging -- Nuclear imaging -- Endoscopic ultrasound -- Advanced therapeutic endoscopy -- Esophageal surgery -- Surgery for peptic ulcer disease -- Surgical approach to the acute abdomen -- Colorectal surgery : polyposis syndromes and inflammatory bowel disease -- Obesity and surgical weight loss -- Minimally invasive surgery -- Clinical vignettes.
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Morbid obesity in adolescents : conservative treatment and surgical approaches

https://libcat.nshealth.ca/en/permalink/provcat33920
Kurt Widhalm, Gerhard Prager, editors. --Wien: Springer , c2015.
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Online
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Other Authors
Widhalm, Kurt
Prager, Gerhard
Responsibility
Kurt Widhalm, Gerhard Prager, editors
Place of Publication
Wien
Publisher
Springer
Date of Publication
c2015
Physical Description
1 online resource (viii, 192 pages)
ISBN
9783709109687 (electronic bk.)
Subjects (MeSH)
Obesity, Morbid - surgery
Obesity, Morbid - therapy
Subjects (LCSH)
Morbid obesity - Treatment
Morbid obesity - Surgery
Obesity in adolescence - Treatment
Contents
1. Paediatric Body Composition Measurement Techniques in Morbidly Obese Patients -- 2. Insulin Resistance in the Morbidly Obese Adolescent -- 3. Inflammation as a Trigger for Insulin Resistance and Cardiometabolic Disease -- 4. Inpatient Lifestyle Interventions to Treat Childhood Obesity -- 5. Conservative Treatment for Morbidly Obese Adolescents: The German Experience -- 6. Comorbidities: Non Alcoholic Fatty Liver in Childhood Obesity -- 7. Measurement of Atherosclerosis in Morbidly Obese Adolescents -- 8. Arthritis and Joint Problems in Morbidly Obese Adolescents -- 9. Bariatric Surgery in Adolescents: Practical Guidelines from a Pediatrician’s Point of View -- 10. Vitamin Deficiencies After Bariatric Surgery? -- 11. Laparoscopic Gastric Banding -- 12. Metabolic Surgery in Adolescents -- 13. Situation in Sweden -- 14. Experiences from Adolescents at the Viennese Center for Bariatric Surgery -- 15. Is There an Indication for BPD-DS/BPD? What the Potential Advantages/Disadvantages to RYNGB? -- 16. Psychological, Nutritional and Sports-Scientific Aspects of Obesity in Adolescence -- 17. Current Guidelines of Bariatric Surgery in Adolescents -- 18. Cardiovascular Risk in Childhood Obesity.
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e-Book
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Lipid Management : From Basics to Clinic

https://libcat.nshealth.ca/en/permalink/provcat39125
Hussein Yassine, editor. --Cham: Springer , c2015.
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This timely, concise title provides an important update on clinical lipid management. Using information from recent clinical trials and in special populations, the book begins by offering an easy-to-read overview of LDL, HDL, and triglyceride metabolism and the genetics of lipid disorders. The link between inflammation and lipids, and how this relates to atherosclerosis development, is also addressed, as are the measures of subclinical atherosclerosis in patients with abnormal lipid levels. Lip…
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Other Authors
Yassine, Hussein
Responsibility
Hussein Yassine, editor
Place of Publication
Cham
Publisher
Springer
Date of Publication
c2015
Physical Description
1 online resource (xiv, 269 p. : 17 illus., 8 illus. in color)
ISBN
9783319111612
9783319111605 (print ed.)
Subjects (MeSH)
Cholesterol, HDL
Cholesterol, LDL
Lipid Metabolism Disorders - complications
Lipid Metabolism Disorders - drug therapy
Abstract
This timely, concise title provides an important update on clinical lipid management. Using information from recent clinical trials and in special populations, the book begins by offering an easy-to-read overview of LDL, HDL, and triglyceride metabolism and the genetics of lipid disorders. The link between inflammation and lipids, and how this relates to atherosclerosis development, is also addressed, as are the measures of subclinical atherosclerosis in patients with abnormal lipid levels. Lipid abnormalities in children, with a particular focus on vulnerable populations (with an emphasis on ethnicity and childhood obesity), are covered. The treatment goals and approaches for managing lipids in the clinic are thoroughly discussed, emphasizing the important role of statin use and addressing controversies of lipid management in special populations such as heart failure, end stage kidney disease and fatty liver disease. Of special note, an important update on how new HIV medications impact lipid levels is provided. In all, Lipid Management: From Basics to Clinic, is an invaluable, handy resource for understanding changes in lipids in different populations and for sharpening the clinical approach to managing complicated lipid cases.
Contents
Basics in Lipoprotein Metabolism -- Genetics of Lipid Disorders -- Lipid and Inflammation in Atherosclerosis -- Dyslipidemia: Relationship to Insulin Resistance, Fatty Liver, and Sub-clinical atherosclerosis -- Is low HDL cholesterol a marker of a mediator of cardiovascular disease? -- Approach to the patient with lipid disorders -- The Effects of Diet in Hyperlipidemia -- Statins -- Non-alcoholic Fatty Liver Disease (NAFLD): The Lipid Disease of the Liver and the Effect of Statins -- The Role of Statins in Heart Failure -- Statins in Chronic Kidney Disease -- Non-Statin Treatment of Dyslipidemia -- LDL Apheresis -- Dyslipidemia in HIV -- New and Emerging Therapies for Hyperlipidemia.
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e-Book
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Online
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Innovative Medicine : Basic Research and Development

https://libcat.nshealth.ca/en/permalink/provcat43980
Kazuwa Nakao, Nagahiro Minato, Shinji Uemoto, editors. --Tokyo: SpringerOpen , c2015.
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This book is devoted to innovative medicine, comprising the proceedings of the Uehara Memorial Foundation Symposium 2014. It remains extremely rare for the findings of basic research to be developed into clinical applications, and it takes a long time for the process to be achieved. The task of advancing the development of basic research into clinical reality lies with translational science, yet the field seems to struggle to find a way to move forward. To create innovative medical technology, …
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Other Authors
Nakao, Kazuwa
Minato, Nagahiro
Uemoto, Shinji
Other Authors
Uehara Memorial Foundation Symposium (2014 : Tokyo Japan)
Responsibility
Kazuwa Nakao, Nagahiro Minato, Shinji Uemoto, editors
Place of Publication
Tokyo
Publisher
SpringerOpen
Date of Publication
c2015
Physical Description
1 online resource (ix, 339 p.)
ISBN
9784431556510
9784431556527 (Print ed.)
9784431556503 (Print ed.)
9784431562467 (Print ed.)
Subjects (MeSH)
Biomedical Research
Biomedical Technology
Translational Medical Research
Specialty
Biomedical Technology
Research
Abstract
This book is devoted to innovative medicine, comprising the proceedings of the Uehara Memorial Foundation Symposium 2014. It remains extremely rare for the findings of basic research to be developed into clinical applications, and it takes a long time for the process to be achieved. The task of advancing the development of basic research into clinical reality lies with translational science, yet the field seems to struggle to find a way to move forward. To create innovative medical technology, many steps need to be taken: development and analysis of optimal animal models of human diseases, elucidation of genomic and epidemiological data, and establishment of “proof of concept”. There is also considerable demand for progress in drug research, new surgical procedures, and new clinical devices and equipment. While the original research target may be rare diseases, it is also important to apply those findings more broadly to common diseases. The book covers a wide range of topics and is organized into three complementary parts. The first part is basic research for innovative medicine, the second is translational research for innovative medicine, and the third is new technology for innovative medicine. This book helps to understand innovative medicine and to make progress in its realization.
Contents
Part I. Basic Research for Innovative Medicine -- 1. Diverting Glycolysis to Combat Oxidative Stress -- 2. Metabolic Regulation by Nuclear Receptors -- 3. Fighting Fire with Fire in Cancer -- 4. Linear Polyubiquitination: a Crucial Regulator of NF-kB Activation -- 5. VCP, a major ATPase in the cells, as a novel drug target for currently incurable disorders -- 6. Roles of E-cadherin in hepatocarcinogenesis -- 7. The Hippo Signaling Pathway: A Candidate New Drug Target for Malignant Tumors -- 8. Inhibitory immunoreceptors on mast cells in allergy and inflammation -- 9. Doxycycline-inducible Autoimmune Blistering Skin Disease Model -- 10. T-cell Senescence and Autoimmunity -- Part II. Translational Research for Innovative Medicine -- 11. IL-6: A new era for the treatment of autoimmune inflammatory diseases -- 12. Pathogenesis of Non-alcoholic Steatohepatitis and Its Potential Therapeutic Strategies -- 13. Multifaceted translational approach of major mental illness -- 14. Translational research of leptin in lipodystrophy and its related diseases -- 15. Translational research of the activation of the C-type natriuretic peptide (CNP)-guanylyl cyclase-B pathway for skeletal dysplasia -- 16. Clarity and Challenges in Tissue Fibrosis -- 17. TRP Channels: Their Function and Potentiality as Drug Targets -- 18. Autophagic Cell Death and Cancer Chemotherapeutics -- 19. Adrenomedullin as a Potential Therapeutic Agent for Refractory Ulcerative Colitis -- 20. RNA activation -- Part III. New Technology for Innovative Medicine -- 21. Cardiac Reprogramming for Heart Repair -- 22. Development of a new in vivo optical probe for biological diagnosis and therapy -- 23. Introduction of mesenchymal stem cells for liver surgery (hepatectomy and transplantation) -- 24. Synaptic and axonal plasticity induction in the human cerebral cortex -- 25. TIM-3 is a novel therapeutic target for eradicating acute myelogenous leukemia stem cells -- 26. TGF-beta LAP degradation products, a novel biomarker and promising therapeutic target for liver fibrogenesis -- 27. Cell-based regenerative therapy for liver disease.
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Disease Recurrence After Liver Transplantation : Natural History, Treatment and Survival

https://libcat.nshealth.ca/en/permalink/provcat39701
Paul J. Thuluvath, editor. (1st ed.) --New York, NY: Springer , c2016.
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As there is a high incidence of disease recurrence after liver transplantation, this volume is designed around the need for a reference text dealing exclusively with this problem. The book places special emphasis on pre- and post-transplant predictors of recurrence, severity assessment, prophylaxis, and treatment. Pathobiology of disease recurrence is discussed in detail where applicable. Issues including quality of life and cost burden are also covered in the text. Written by well-known author…
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Other Authors
Thuluvath, Paul J
Responsibility
Paul J. Thuluvath, editor
Edition
1st ed.
Place of Publication
New York, NY
Publisher
Springer
Date of Publication
c2016
Physical Description
1 online resource (ix, 269 p. : 34 illus., 17 illus. in color)
ISBN
9781493929474
9781493929467 (print ed.)
Subjects (MeSH)
Liver Diseases - complications
Liver Transplantation
Prognosis
Recurrence
Risk Factors
Abstract
As there is a high incidence of disease recurrence after liver transplantation, this volume is designed around the need for a reference text dealing exclusively with this problem. The book places special emphasis on pre- and post-transplant predictors of recurrence, severity assessment, prophylaxis, and treatment. Pathobiology of disease recurrence is discussed in detail where applicable. Issues including quality of life and cost burden are also covered in the text. Written by well-known authorities in each field, Disease Recurrence After Liver Transplantation: Natural History, Treatment and Survival serves as a comprehensive reference for physicians and surgeons who take care of liver transplant recipients and a major addition to the literature detailing the current understanding of disease recurrence.
Contents
Overview: Disease Recurrence After Liver Transplantation -- Hepatitis B Recurrence: Major Milestones and Current Status -- HCV Recurrence: Predictors and Outcomes after Liver Transplantation -- Treatment of Recurrent Hepatitis C -- Recurrence of Primary Biliary Cirrhosis Following Liver Transplantation -- Recurrence of Autoimmune Hepatitis after Liver Transplantation -- Alcoholic Cirrhosis, Transplantation, and Recurrence of Disease -- Recurrence of Primary Sclerosing Cholangitis after Liver Transplantation -- Recurrence of Metabolic Disorders after Liver Transplantation -- Non-Alcoholic Fatty Liver Disease Post Liver Transplantation -- Recurrence of Hepatocellular Carcinoma Following Liver Transplantation within Milan Criteria -- Recurrence of HCC When Transplanted Outside Milan Criteria -- Role of Neoadjuvant and Adjuvant Treatment in HCC Recurrence after Liver Transplantation -- Cholangiocarcinoma -- Recurrent Non-hepatic and De-novo Malignancies after Liver Transplantation -- Recurrence of Disease after Liver Transplantation in the Pediatric Population -- Disease Recurrence after Liver Transplantation: Quality of Life and Cost of Retransplantation.
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e-Book
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Online
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Obesity, Bariatric and Metabolic Surgery : A Practical Guide

https://libcat.nshealth.ca/en/permalink/provcat39736
Sanjay Agrawal, editor. (1st ed.) --Cham: Springer , c2016.
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This practical and comprehensive book covers all the aspects of bariatric and metabolic surgery including perioperative management, surgical techniques of common as well as newer procedures, complications and outcomes. There are dedicated sections on revisional surgery, single incision surgery and innovative endoscopic procedures. The book is well illustrated with photos and video clips along with step-by-step guidance for a complete range of Bariatric procedures. Medical aspects of obesity and…
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Other Authors
Agrawal, Sanjay
Responsibility
Sanjay Agrawal, editor
Edition
1st ed.
Place of Publication
Cham
Publisher
Springer
Date of Publication
c2016
Physical Description
1 online resource (xxviii, 736 p. : 415 illus., 327 illus. in color)
ISBN
9783319043432
9783319043425 (print ed.)
Subjects (MeSH)
Bariatric Surgery - methods
Obesity - surgery
Abstract
This practical and comprehensive book covers all the aspects of bariatric and metabolic surgery including perioperative management, surgical techniques of common as well as newer procedures, complications and outcomes. There are dedicated sections on revisional surgery, single incision surgery and innovative endoscopic procedures. The book is well illustrated with photos and video clips along with step-by-step guidance for a complete range of Bariatric procedures. Medical aspects of obesity and metabolic syndrome are included in the introductory sections, and the last two sections cover diverse topics in this exciting field of bariatric surgery. Written by leading experts, Obesity, Bariatric and Metabolic Surgery: A Practical Guide serves as an excellent manual for a wide range of healthcare professionals including Bariatric Surgeons, General Surgeons, Trainees, Physicians, Anaesthesiologists, Dieticians, Psychologists, Psychiatrists, Radiologists and Nursing staff. Foreword by IFSO President: "excellent reference guide". Foreword by BOMSS President: "perfect guide for the bariatric surgeon....most modern and comprehensive textbook".
Contents
Section I. Obesity and Metabolic Syndrome -- 1. Introduction to Obesity -- 2. Etiopathogenesis of Obesity -- 3. Gut-derived Hormones and Energy Homeostasis -- 4. Health Consequences--Obesity Associated Comorbidities -- 5. Medical Management of Obesity -- Section II. Introduction to Bariatric Surgery -- 6. Historical Perspectives of Bariatric Surgery -- 7. Evidence Base for Bariatric Surgery -- 8. Patient Selection in Bariatric Surgery -- 9. Procedure Selection in Bariatric Surgery -- Section III. Perioperative Assessment for Bariatric Surgery -- 10. Preoperative Medical Evaluation of the Bariatric Surgery Patient -- 11. Perioperative Dietary Evaluation of the Bariatric Surgery Patient -- 12. Psychological Assessment of the Bariatric Surgery Patient -- 13. Anaesthesia Considerations in the Obese Patient -- 14. Perioperative Risk Scoring System in Bariatric Surgery -- 15. The Structure and Role of the Multidisciplinary Team in Bariatric Surgery -- 16. Nursing Care of the Bariatric Surgery Patient -- 17. Perioperative Management of the Bariatric Surgery Patient -- 18. Enhanced Recovery after Bariatric Surgery -- Section IV. Laparoscopic Roux-en-Y Gastric Bypass (LRYGB): Techniques, Complications, Outcomes and Controversies -- 19. Laparoscopic Roux-en-Y Gastric Bypass: The Linear Technique -- 20. Laparoscopic Roux-en-Y Gastric Bypass: The Circular Stapler Technique (Including Transoral as well as Transabdominal Anvil Placement) -- 21. Laparoscopic Roux-en-Y Gastric Bypass: Hand-Sewn Technique -- 22. Laparoscopic Roux-en-Y Gastric Bypass: The Fully Stapled Technique -- 23. Laparoscopic Roux-en-Y Gastric Bypass: Complications- Diagnosis and Management -- 24. Laparoscopic Roux-en-Y Gastric Bypass: Outcomes -- 25. Laparoscopic Roux-en-Y Gastric Bypass: Current Controversies -- Section V. Laparoscopic Sleeve Gastrectomy (LSG): Technique, Complications, Outcomes and Controversies -- 26 Laparoscopic Sleeve Gastrectomy: The Technique -- 27 Laparoscopic Sleeve Gastrectomy: Complications, Diagnosis and Management -- 28 Laparoscopic Sleeve Gastrectomy: Outcomes -- 29 Laparoscopic Sleeve Gastrectomy: Current Controversies -- Section VI. Laparoscopic Adjustable Gastric Banding (LAGB): Technique, Complications, Outcomes and Controversies -- 30 Laparoscopic Adjustable Gastric Banding: The Technique -- 31 Laparoscopic Adjustable Gastric Banding: Complications- Diagnosis and Management -- 32 Laparoscopic Adjustable Gastric Banding: Outcomes -- 33 Laparoscopic Adjustable Gastric Banding: Current Controversies -- Section VII. Advances in Minimally Invasive Bariatric Surgery -- 34 Reduced Port Laparoscopic Bariatric Surgery -- 35 Single Incision Laparoscopic Roux-en-Y Gastric Bypass -- 36 Single Incision Laparoscopic Sleeve Gastrectomy -- 37 Single Incision Laparoscopic Adjustable Gastric Banding -- 38 Robotic Assisted Bariatric Surgery -- Section VIII. Revisional Bariatric Surgery -- 39 Revisional Surgery after Vertical Banded Gastroplasty -- 40 Revisional Surgery after Laparoscopic Roux-en-Y Gastric Bypass -- 41 Revisional Surgery after Laparoscopic Sleeve Gastrectomy -- 42 Revisional Bariatric Surgery after Laparoscopic Adjustable Gastric Banding -- Section IX. Other Operations for Obesity -- 43 Laparoscopic Mini-Gastric (One Anastomosis) Bypass Surgery -- 44 Laparoscopic Biliopancreatic Diversion with Duodenal Switch (BPD-DS) Surgery -- 45 Laparoscopic Biliopancreatic Diversion (BPD) Surgery -- 46 Laparoscopic Banded Gastric Bypass Surgery -- 47 Single-Anastomosis Duodeno-Ileal Bypass with Sleeve Gastrectomy (SADI-S) Surgery -- 48 Laparoscopic Gastric Plication -- 49 Laparoscopic Gastric Pacing -- Section X. Endoscopic Approaches in Obesity and Bariatric Surgery -- 50 Intragastric Balloon Treatment for Obesity -- 51 Endoscopic Duodeno-Jejunal Bypass Sleeve Treatment for Obesity -- 52 Newer Endoluminal Interventions for Obesity -- 53 Endoscopic Treatment of Complications after Bariatric Surgery -- Section XI. Metabolic Effects of Bariatric Surgery -- 54 Mechanisms of Action of Bariatric Surgical Procedures -- 55 Glycemic Control and Reduction of Cardiovascular Risk following Bariatric Surgery -- 56 Resolution of Obesity Associated Comorbidities (Diabetes, Hypertension, Sleep Apnea and Metabolic Syndrome) following Bariatric Surgery -- 57 Metabolic Surgery for Type 2 Diabetes Mellitus in Patients with Body Mass Index less than 35 kg/m2 -- 58 Ileal Interposition with Sleeve Gastrectomy for Type 2 Diabetes Mellitus and Metabolic Syndrome -- Section XII. Training, Reporting and Practice in Bariatric Surgery -- 59 Training in Bariatric Surgery -- 60 Bariatric Surgery Data Management and Reporting Worldwide -- 61 Surgical Review Corporation (SRC) Center of Excellence Programs for Bariatric Surgery -- 62 International Federation for Surgical Obesity (IFSO) Center of Excellence Program for Bariatric Surgery -- 63 Metabolic and Bariatric Surgery Accreditation and Quality Improvement Program (MBSAQIP) by American Society for Metabolic and Bariatric Surgery (ASMBS) for Bariatric Surgery -- 64 Medicolegal Issues in Bariatric Surgery -- Section XIII. Miscellaneous Topics -- 65 Nutritional Management of the Bariatric Surgery Patient -- 66 Management of Extreme Obesity (Body Mass Index greater than 60 Kgm2) -- 67 Respiratory Considerations and Effect of Bariatric Surgery in the Obese Patient -- 68 Infertility, Pregnancy and Bariatric Surgery -- 69 Non-Alcoholic Fatty Liver Disease (NAFLD) and Bariatric Surgery -- 70 Cancer, Obesity and Bariatric Surgery -- 71 Psychological Issues Before and After Bariatric Surgery -- 72 Health-Related Quality of Life Before and After Bariatric Surgery -- Section XIV. Special Topics -- 73 Management of Bariatric Emergencies by the General Surgeon -- 74 The Role of Primary Care in Bariatric Surgery -- 75 Intensive Care and Obesity -- 76 Radiological Imaging in Bariatric Surgery -- 77 Adolescent Bariatric Surgery -- 78 Body Contouring after Bariatric Surgery.
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e-Book
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Obesity : A Practical Guide

https://libcat.nshealth.ca/en/permalink/provcat39814
Shamim I. Ahmad, Syed Khalid Imam, editors. (1st ed.) --Cham: Springer , c2016.
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This comprehensive book examines the causes and effects of obesity, both on the human body as well as society as a whole. The significance obesity plays in the development of a variety of lethal and non-lethal diseases is discussed, and the prevention and treatment of obesity is looked at in detail. Obesity: A Practical Guide brings together a large number of international specialists in their field, and is aimed at Gastroenterologists, Surgeons, Researchers, Dieticians, Physicians and Health C…
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Ahmad, Shamim I
Imam, Syed Khalid
Responsibility
Shamim I. Ahmad, Syed Khalid Imam, editors
Edition
1st ed.
Place of Publication
Cham
Publisher
Springer
Date of Publication
c2016
Physical Description
1 online resource (xxii, 362 p. : 26 illus., 16 illus. in color)
ISBN
9783319198217
9783319198200 (print ed.)
Subjects (MeSH)
Obesity - complications
Obesity - metabolism
Abstract
This comprehensive book examines the causes and effects of obesity, both on the human body as well as society as a whole. The significance obesity plays in the development of a variety of lethal and non-lethal diseases is discussed, and the prevention and treatment of obesity is looked at in detail. Obesity: A Practical Guide brings together a large number of international specialists in their field, and is aimed at Gastroenterologists, Surgeons, Researchers, Dieticians, Physicians and Health Care providers.
Contents
1. White Adipose Tissues: Beyond Fat Storage -- 2. Brown Adipose Tissue and Obesity -- 3. Long-Chain Omega-3 Polyunsaturated Fatty Acids and Obesity -- 4. Leptin and Obesity -- 5. Role of Neuro-Endocrine System in Obesity -- 6. Oxidative Stress and Obesity -- 7. Genetics of Obesity -- 8. Obesity and Coronary Heart Disease -- 9. Obesity and Diabetes -- 10. Obesity and Breathing Related Sleep Disorder -- 11. Gastro-Oesophageal Reflux Disease and Obesity: Pathophysiology and Putative Treatment -- 12. Obesity and Gastrointestinal Disorder in Children -- 13. Non-Alcoholic Fatty Liver Disease in Obesity -- 14. Obesity, Cardiometabolic Risk, and Chronic Kidney Disease -- 15. Polycystic Ovary Syndrome and Obesity -- 16. Obesity and Cancer -- 17. Obesity and Thyroid Cancer -- 18. Depression and Obesity -- 19. Obesity in Orthopedics and Trauma Surgery -- 20. New Technology in the Assessment and Treatment of Obesity -- 21. Obstetrical Risk in Obesity -- 22. Bariatric Surgery in Obesity -- 23. Decoding the Code: Underlying Physiological Mechanisms of Bariatric Surgery -- 24. Infant Nutrition and Obesity -- 25. Disordered Eating and Obesity -- 26. Physical Activity in Obesity and Diabetes -- 27. Obesity Prevention in Young Children.
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e-Book
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Online
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Alcoholic and Non-Alcoholic Fatty Liver Disease : Bench to Bedside

https://libcat.nshealth.ca/en/permalink/provcat39826
Naga Chalasani, Gyongyi Szabo, editors. --Cham: Springer , c2016.
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This volume is the first text to concisely yet comprehensively cover developments for both alcoholic and non-alcoholic fatty liver disease in an organized fashion. Aspects of these two diseases covered in the book include global epidemiology and risk factors, pathogenesis, animal models, hepatic and extra-hepatic malignancies, treatment models, and current and emerging therapies. Written by experts in the field, Alcoholic and Non-Alcoholic Fatty Liver Disease: Bench to Bedside is a valuable res…
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Other Authors
Chalasani, Naga
Szabo, Gyongyi
Responsibility
Naga Chalasani, Gyongyi Szabo, editors
Place of Publication
Cham
Publisher
Springer
Date of Publication
c2016
Physical Description
1 online resource (xvi, 372 p. : 47 illus., 36 illus. in color)
ISBN
9783319205380
9783319205373 (print ed.)
Subjects (MeSH)
Fatty Liver, Alcoholic
Non-alcoholic Fatty Liver Disease
Abstract
This volume is the first text to concisely yet comprehensively cover developments for both alcoholic and non-alcoholic fatty liver disease in an organized fashion. Aspects of these two diseases covered in the book include global epidemiology and risk factors, pathogenesis, animal models, hepatic and extra-hepatic malignancies, treatment models, and current and emerging therapies. Written by experts in the field, Alcoholic and Non-Alcoholic Fatty Liver Disease: Bench to Bedside is a valuable resource for gastroenterologists, pathologists, and hepatologists who treat patients with alcoholic and nonalcoholic fatty liver disease.
Contents
Epidemiology and Risk Factors for Alcoholic Liver Disease -- Global Epidemiology and Risk Factors for Non-Alcoholic Fatty Liver Disease -- Pathogenesis of Alcoholic Liver Disease -- Pathogenesis of NAFLD and NASH -- Animal Models of Alcoholic Liver Disease -- Animal Models of Nonalcoholic Fatty Liver Disease -- Genetic Basis of Alcoholic and Nonalcoholic Fatty Liver Disease -- Clinical Features, Disease Modifiers and Natural History of Alcoholic Liver Disease -- Nonalcoholic Fatty Liver Disease (NAFLD): Clinical Features, Disease Modifiers, and Natural History -- Diagnostic Approaches and Clinical Endpoints of Treatment in Alcoholic Liver Disease -- Diagnostic Considerations and Clinical Endpoints for Nonalcoholic Steatohepatitis -- Pathology of Alcoholic and Non-Alcoholic Fatty Liver Disease -- Hepatic and Extra-Hepatic Malignancies in Alcoholic Liver Disease -- Hepatic and Extra-Hepatic Malignancies in NAFLD -- Treatment of Alcoholic Liver Disease Including Emerging therapies, Novel targets and Liver transplantation -- Current and Emerging Therapies for Non-Alcoholic Fatty Liver Disease -- Nonalcoholic Fatty Liver Disease in Children.
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e-Book
Location
Online
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