Fatty liver disease
https://libcat.nshealth.ca/en/permalink/chpams35494
Nova Scotia Health Authority. QEII. Hepatology Services.
Halifax, NS:
Nova Scotia Health Authority
, 2021.
- Pamphlet Number
- 1203
- Available Online
- View Pamphlet
Fatty liver disease happens when there is a buildup of extra fat cells in the liver. This pamphlet explains how fatty liver disease is diagnosed and what to do if you are diagnosed with fatty liver disease. A website for further information is given.
- Available Online
- View Pamphlet
- Corporate Author
- Nova Scotia Health Authority. QEII. Hepatology Services
- Place of Publication
- Halifax, NS
- Publisher
- Nova Scotia Health Authority
- Date of Publication
- 2021
- Format
- Pamphlet
- Language
- English
- Physical Description
- 1 electronic document ([1] p.) : digital, PDF file
- Subjects (MeSH)
- Fatty Liver
- Non-alcoholic Fatty Liver Disease
- Subjects (LCSH)
- Fatty liver
- Liver--Diseases
- Specialty
- Digestive System
- Abstract
- Fatty liver disease happens when there is a buildup of extra fat cells in the liver. This pamphlet explains how fatty liver disease is diagnosed and what to do if you are diagnosed with fatty liver disease. A website for further information is given.
- Responsibility
- Prepared by: Hepatology Services, VG site, QEII
- Pamphlet Number
- 1203
International Perspectives in Values-Based Mental Health Practice : Case Studies and Commentaries
https://libcat.nshealth.ca/en/permalink/provcat45714
Drozdstoy Stoyanov, Bill Fulford, Giovanni Stanghellini, Werdie Van Staden, Michael TH Wong, editors.
--Cham:
Springer
, c2021.
- Available Online
- View e-Book
- Location
- Online
This open access book offers essential information on values-based practice (VBP): the clinical skills involved, teamwork and person-centered care, links between values and evidence, and the importance of partnerships in shared decision-making. Different cultures have different values; for example, partnership in decision-making looks very different, from the highly individualized perspective of European and North American cultures to the collective and family-oriented perspectives common in So…
- Available Online
- View e-Book
- Other Authors
- Stoyanov, Drozdstoy
- Fulford, Bill
- Stanghellini, Giovanni
- Van Staden, Werdie
- Wong, Michael T.H.
- Responsibility
- Drozdstoy Stoyanov, Bill Fulford, Giovanni Stanghellini, Werdie Van Staden, Michael TH Wong, editors
- Place of Publication
- Cham
- Publisher
- Springer
- Date of Publication
- c2021
- Physical Description
- 1 online resource (xviii, 436 p.) : 10 illus., 8 illus. in color
- ISBN
- 9783030478520
- 9783030478513 (Print ed.)
- 9783030478537 (Print ed.)
- 9783030478544 (Print ed.)
- Subjects (MeSH)
- Bioethical Issues
- Cultural Competency
- Culturally Competent Care
- Ethics, Clinical
- Mental Health Services - ethics
- Abstract
- This open access book offers essential information on values-based practice (VBP): the clinical skills involved, teamwork and person-centered care, links between values and evidence, and the importance of partnerships in shared decision-making. Different cultures have different values; for example, partnership in decision-making looks very different, from the highly individualized perspective of European and North American cultures to the collective and family-oriented perspectives common in South East Asia. In turn, African cultures offer yet another perspective, one that falls between these two extremes (called batho pele). The book will benefit everyone concerned with the practical challenges of delivering mental health services. Accordingly, all contributions are developed on the basis of case vignettes, and cover a range of situations in which values underlie tensions or uncertainties regarding how to proceed in clinical practice. Examples include the patient’s autonomy and best interest, the physician’s commitment to establishing high standards of clinical governance, clinical versus community best interest, institutional versus clinical interests, patients insisting on medically unsound but legal treatments etc. Thus far, VBP publications have mainly dealt with clinical scenarios involving individual values (of clinicians and patients). Our objective with this book is to develop a model of VBP that is culturally much broader in scope. As such, it offers a vital resource for mental health stakeholders in an increasingly inter-connected world. It also offers opportunities for cross-learning in values-based practice between cultures with very different clinical care traditions.
- Contents
- 1. Surprised by Values: An Introduction to Values-Based Practice and the Use of Personal Narratives in This Book -- Part I. Exemplars -- 2. Migration Narratives: An Introduction to Part I, Exemplars -- 3. Antonella: ‘A Stranger in the Family’—A Case Study of Eating Disorders Across Cultures - 4. The Role of Culture, Values and Trauma in Shaping Abnormal Bodily Experience in Migrants -- 5. Premorbid Personality and Expatriation as Possible Risk Factors for Brief Psychotic Disorder: A Case Report from Post-Soviet Bulgaria -- Part II. Theory -- 6. Theory First: An Introduction to Part II, Theory -- 7. The Will to Beauty as a Therapeutic Agent: Aesthetic Values in the Treatment of Addictive Disorders -- 8. Anorexia as Religion: Ocularcentrism as a Cultural Value and a Compensation Strategy in Persons with Eating Disorders -- 9. Ethos, Embodiment, Psychosis: Losing One’s Home-Identity Stakes -- 10. African Personhood, Humanism, and Critical Sankofaism: The Case of Male Suicide in Ghana -- 11. Madness, Mythopoetry and Medicine -- 12. Inside and Out: How Western Patriarchal Cultural Contexts Shape Women’s Relationships with Their Bodies -- 13. Spiritual, Religious and Ethical Values in a Suicidal Individual -- 14. Cultural Values, Religion and Psychosis: Five Short Stories -- Part III. Practice -- 15. Vectors of Best Practice: An Introduction to Part III, Practice -- 16. Cross-Cultural Factors and Identity in Adolescence -- 17. Multidisciplinary Teamwork and the Insanity Defence: A Case of Infanticide in Iraq -- 18. Colonial Values and Asylum Care in Brazil: Reclaiming the Streets Through Carnival in Rio de Janeiro -- 19. Alcohol Use Disorder in a Culture That Normalizes the Consumption of Alcoholic Beverages: The Conflicts for Decision-Making -- 20. Living at the Edge of Compromise: Balkan Pluralism as a Resource for Balanced Decision-Making -- 21. “Thinking Too Much”: A Clash of Legitimate Values in Clinical Practice Calls for an Indaba Guided by African Values-Based Practice -- 22. Three Points in Time: How Values and Culture Affected My Life, Madness and the People Around Me -- 23. Recovery and Cultural Values: On Our Own Terms (A Dialogue) -- Part IV. Science -- 24. Linking Science with People: An Introduction to Part IV, Science -- 25. A Cross-Cultural Values-Based Approach to the Diagnosis and Treatment of Dissociative (Conversion) Disorders -- 26. Treatment of Social Anxiety Disorder or Neuroenhancement of Socially Accepted Modesty? The Case of Ms. Suzuki -- 27. Non-traditional Religion, Hyper-Religiosity and Psychopathology: The Story of Ivan from Bulgaria -- 28. Journey into Genes: Cultural Values and the (Near) Future of Genetic Counselling in Mental Health -- 29. Policy-Making Indabas to Prevent “Not Listening”: An Added Recommendation from the Life Esidimeni Tragedy -- 30. Covert Treatment in a Cross-Cultural Setting -- 31. Discouragement Towards Seeking Health Care of Older People in Rural China: The Influence of Culture and Structural Constraints -- 32. Discovering Myself, a Journey of Rediscovery -- Part V. Training -- 33. Training for Task: An Introduction to Part V, Training -- 34. Values-Based Practice When Engaging with Voice-Hearers -- 35. Dharma Therapy: A Buddhist Counselling Approach to Acknowledging and Enhancing Perspectives, Attitudes and Values - 36. Dangerous Liaisons: Science, Tradition, and Qur’anic Healing in the Dakhla Oasis of Egypt -- 37. Know Thyself: Jane Discovers the Value of Her Depression -- 38. Case Studies in the Culture of Professional Football Players and Mental Welfare and Wellbeing -- 39. Sexual Orientation Change Efforts and VBP -- 40. Values, Meanings, Hermeneutics and Mental Health -- 41. Disha: Building Bridges-Removing Barriers: Where Excluded and Privileged Young Adults Meet -- 42. Online Counseling “The World Without a Label” -- Part VI. Reflections -- 43. The Realpolitik of Values-Based Practice: An Introduction to Part VI, Reflections -- 44. Reflections on the Impact of Mental Health Ward Staff Training in Race Equality and Values-Based Practice -- 45. Connecting Patients, Practitioners and Regulators in Supporting Positive Experiences and Processes of Shared Decision-Making: A Case Study in Co-production -- 46. Beyond the Color Bar: Sharing Narratives in Order to Promote a Clearer Understanding of Mental Health Issues Across Cultural and Racial Boundaries -- 47. Co-writing Values: What We Did and Why We Did It -- After Word: Where Next with the Book.
- Format
- e-Book
- Publication Type
- Case Reports
- Location
- Online
Diabetes : from Research to Clinical Practice, volume 4
https://libcat.nshealth.ca/en/permalink/provcat46408
Md. Shahidul Islam, editor.
--Cham:
Springer
, c2021.
- Available Online
- View e-Book
- Access
- NEW Springer 2021
- Holdings
- Halifax Infirmary: v. 29, 1980 - v. 45, 1996.
- Location
- Online
This contributed volume discusses the most important aspects of diabetes in 27 selected chapters contributed by experts in the field. Its contents range from essential background information to recent advances, state-of-the-art treatments and in-depth discussions on many of the critical issues involved in diabetes pathophysiology and therapy. Throughout these pages, the most important areas of uncertainties and future directions of research have been outlined, covering a wide range of topics in…
- Available Online
- View e-Book
- Other Authors
- Islam, Md. Shahidul
- Responsibility
- Md. Shahidul Islam, editor
- Place of Publication
- Cham
- Publisher
- Springer
- Date of Publication
- c2021
- Holdings
- Halifax Infirmary: v. 29, 1980 - v. 45, 1996.
- Physical Description
- 1 online resource (xi, 582 p.) : 50 illus., 30 illus. in color
- Series Vol.
- 1307
- ISBN
- 9783030510893
- 9783030510886 (Print ed.)
- 9783030510909 (Print ed.)
- 9783030510916 (Print ed.)
- ISSN
- 0012-1797
- Subjects (MeSH)
- Diabetes Complications
- Diabetes Mellitus - physiopathology
- Diabetes Mellitus - therapy
- Specialty
- Diabetes Mellitus
- Abstract
- This contributed volume discusses the most important aspects of diabetes in 27 selected chapters contributed by experts in the field. Its contents range from essential background information to recent advances, state-of-the-art treatments and in-depth discussions on many of the critical issues involved in diabetes pathophysiology and therapy. Throughout these pages, the most important areas of uncertainties and future directions of research have been outlined, covering a wide range of topics including latent immune diabetes, hypoglycemia, dietary recommendations, gestational diabetes and diabetes treatments, among others. This book is highly recommended for clinicians, researchers and students interested in diabetes care and research.
- Contents
- Diabetes: from research to clinical practice -- Glucose lowering treatment modalities of type 2 diabetes mellitus -- Latent autoimmune diabetes in adults: a review of clinically relevant issues -- Hypoglycemia -- Hypoglycemia, malnutrition and body composition -- Acute metabolic emergencies in diabetes: DKA, HHS and EDKA -- The role of the Mediterranean dietary pattern on metabolic control of patients with diabetes mellitus: a narrative review -- Glycaemic control and vascular complications in diabetes mellitus type 2 -- Diabetes mellitus and acute myocardial infarction: impact on short and long-term mortality -- Effects of GLP-1 and its analogs on gastric physiology in diabetes mellitus and obesity -- GLP-1 receptor agonists and SGLT2 inhibitors for the treatment of type 2 diabetes: new insights and opportunities for cardiovascular protection -- Glucose lowering efficacy and pleiotropic effects of sodium-glucose cotransporter 2 inhibitors -- Gestational diabetes mellitus screening and diagnosis -- Management of gestational diabetes mellitus -- From entero-endocrine cell biology to surgical interventional therapies for type 2 diabetes -- Laparoscopic vertical sleeve gastrectomy as a treatment option for adults with diabetes mellitus -- Surgical treatment of type 2 diabetes mellitus in youth -- Insulin recommender systems for T1DM: a review -- Algorithms for diagnosis of diabetic retinopathy and diabetic macula edema: a review -- Diabetic macular edema: state of art and intraocular pharmacological approaches -- New concepts in the management of Charcot neuroarthropathy in diabetes -- Non-alcoholic fatty liver disease and diabetes mellitus -- Global experience of diabetes registries: a systematic review -- Diabetes and genetics: a relationship between genetic risk alleles, clinical phenotypes and therapeutic approaches -- Dietary SCFAs immunotherapy: reshaping the gut microbiota in diabetes -- Animal models and renal biomarkers of diabetic nephropathy -- In vivo and in vitro models of diabetes: a focus on pregnancy.
- Access
- NEW Springer 2021
- Format
- e-Book
- Location
- Online
The Critically Ill Cirrhotic Patient : Evaluation and Management
https://libcat.nshealth.ca/en/permalink/provcat44886
Robert S. Rahimi, editor.
--Cham:
Springer
, c2020.
- Available Online
- View e-Book
- Location
- Online
This text provides a comprehensive, state-of-the-art overview of the diagnosis and management of the critically ill cirrhotic patient. The book reviews recent data about risk factors for acute on chronic liver failure (including infection, renal dysfunction and acute alcoholic hepatitis), profiles the latest treatment strategies for the management of variceal bleeding, ascites, hepatocellular carcinoma and presents current and novel therapies for acute hepatic encephalopathy, and anticoagulatio…
- Available Online
- View e-Book
- Other Authors
- Rahimi, Robert S.
- Responsibility
- Robert S. Rahimi, editor
- Place of Publication
- Cham
- Publisher
- Springer
- Date of Publication
- c2020
- Physical Description
- 1 online resource (xv, 369 p.) : 33 illus., 25 illus. in color
- ISBN
- 9783030244903
- 9783030244897 (Print ed.)
- 9783030244910 (Print ed.)
- 9783030244927 (Print ed.)
- Specialty
- Critical Care
- Abstract
- This text provides a comprehensive, state-of-the-art overview of the diagnosis and management of the critically ill cirrhotic patient. The book reviews recent data about risk factors for acute on chronic liver failure (including infection, renal dysfunction and acute alcoholic hepatitis), profiles the latest treatment strategies for the management of variceal bleeding, ascites, hepatocellular carcinoma and presents current and novel therapies for acute hepatic encephalopathy, and anticoagulation in liver disease. The volume also focuses on the changing etiology of liver disease, with an emphasis on obesity and frailty/sarcopenia, and advances in surgical techniques, including living donor liver transplants and gender disparities in liver transplantation. Palliative care for the critically ill liver patient is also discussed in the book. Written by experts in the field, The Critically Ill Cirrhotic Patient: Evaluation and Management is a valuable resource for clinicians, practitioners, health care providers, and researchers who encounter patients with chronic liver disease, including end-stage liver cirrhosis.
- Contents
- Epidemiology and Natural History of Chronic Liver Disease -- Management of Ascites -- Portosystemic Shunt Embolization in Overt Hepatic Encephalopathy -- Gastroesophageal Variceal Bleeding Management -- Renal Dysfunction in Patients with Cirrhosis -- Intensive Care Management of Patients with Cirrhosis -- Infections in Critically Ill Cirrhosis Patients -- Obesity and the Critically Ill Cirrhotic Patient -- Frailty and Sarcopenia in the Critically Ill Patient with Cirrhosis -- Acute Alcoholic Hepatitis -- Acute on Chronic Liver Failure -- Anticoagulation in the Hospitalized Patient with Decompensated Cirrhosis: Management of a Delicate Balance -- The Management of Hepatocellular Carcinoma -- Liver Transplantation -- Gender Disparities in Liver Transplantation -- The Role of Palliative Care in Cirrhosis.
- Format
- e-Book
- Location
- Online
Liver Diseases : A Multidisciplinary Textbook
https://libcat.nshealth.ca/en/permalink/provcat45015
Florentina Radu-Ionita, Nikolaos T. Pyrsopoulos, Mariana Jinga, Ion C. Tintoiu, Zhonghua Sun, Ecaterina Bontas, editors.
--Cham:
Springer
, c2020.
- Available Online
- View e-Book
- Location
- Online
This book provides an in-depth coverage not only of liver pathology but also of diagnosis of the numerous types of liver disease , placing specific emphasis on current treatments of liver pathology including the most up-to-date information on liver transplantation. The first part of provides an in-depth account of the liver pathology in different conditions such as Hepatits, liver ischaemia reperfusion injury, Lyme disease, cirrhotic cardiomyopathy and hepatocellular carcinoma. The second part …
- Available Online
- View e-Book
- Other Authors
- Radu-Ionita, Florentina
- Pyrsopoulos, Nikolaos T.
- Jinga, Mariana
- Tintoiu, Ion C.
- Sun, Zhonghua
- Bontas, Ecaterina
- Responsibility
- Florentina Radu-Ionita, Nikolaos T. Pyrsopoulos, Mariana Jinga, Ion C. Tintoiu, Zhonghua Sun, Ecaterina Bontas, editors
- Place of Publication
- Cham
- Publisher
- Springer
- Date of Publication
- c2020
- Physical Description
- 1 online resource (x, 827 p.) : 247 illus., 203 illus. in color
- ISBN
- 9783030244323
- 9783030244316 (Print ed.)
- 9783030244330 (Print ed.)
- 9783030244347 (Print ed.)
- Subjects (MeSH)
- Liver - pathology
- Liver Diseases - diagnosis
- Liver Diseases - therapy
- Specialty
- Gastroenterology
- Pathology
- Abstract
- This book provides an in-depth coverage not only of liver pathology but also of diagnosis of the numerous types of liver disease , placing specific emphasis on current treatments of liver pathology including the most up-to-date information on liver transplantation. The first part of provides an in-depth account of the liver pathology in different conditions such as Hepatits, liver ischaemia reperfusion injury, Lyme disease, cirrhotic cardiomyopathy and hepatocellular carcinoma. The second part provides a comprehensive overview of diagnostic methods. Of particular interest are chapters on the latest techniques in Patient-specific 3D printing and transient elastography (FibroScan). The final part focuses on treatment and provides a step-by step guide to the therapeutic management of liver diseases starting with pharmacological treatment and techniques including surgery and liver transplantation. This is an invaluable book for clinicians, practitioners including academics, scientists/researchers and postgraduates to provide the newest knowledge in the field of liver pathogenesis. It is written by a multidisciplinary team of experts in hepathology, gastroenterology, and surgery especially from liver transplantation.
- Contents
- Part I: Overview -- 1. Anatomy and Embryology of the Liver -- 2. Liver Histology -- 3. Hepatic Progenitor Cells -- 4. Hepatocellular Death: Apoptosis, Autophagy, Necrosis and Necroptosis -- 5. Steatosis and inflammation in liver pathology -- 6. Molecular basis of fibrogenesis and angiogenesis during chronic liver disease: Impact of TGF-ß and VEGF on pathogenic pathways -- 7. Hepatotoxicity: Mechanisms of Liver Injury -- 8. Crosstalk of molecular signaling in hepatocellular carcinoma -- 9. Drug-Induced Liver Injury -- 10. Acquired Metabolic Disorders -- 11. Vascular Disorders of the Liver -- 12. Liver Ischaemia Reperfusion Injury -- 13. Autoimmune Hepatitis -- 14. Primary Sclerosing Cholangitis -- 15. Parasitic Diseases of the Liver -- 16. Viral Hepatitis B -- 17. Viral hepatitis C -- 18. Non-B, Non-C Viral Hepatitis -- 19. The Microbiome in Liver Diseases -- 20. Polycystic Liver Diseases -- 21. Portopulmonary Hypertension and Hepatopulmonary syndrome -- 22. Hepatic Abscesses -- 23. Liver Cirrhosis -- 24. Primary Biliary Cholangitis -- 25. The Paucity of Interlobular Bile Ducts -- 26. Nonalcoholic Fatty Liver Disease: a wide spectrum disease -- 27. Alcoholic Liver Disease -- 28. Liver Disease in Pregnancy -- 29. Cirrhotic Cardiomyopathy -- 30. Benign Tumors -- 31. Liver Cancer -- 32. Acute Liver Failure -- 33. Chronic Liver Failure and Acute-on-Chronic Liver Failure -- Part II. Diagnostic Methods -- 34. History and Physical Examination -- 35. Assessment of Liver Function -- 36. Noninvasive Biomarkers for liver fibrosis -- 37. Peritoneal Fluid Analysis -- 38. Measurement of Hepatic Venous Pressure Gradient (HVPG) -- 39. Liver Biopsy for Histopathology -- 40. Abdominal Ultrasonography -- 41. Endoscopy in Hepatic Diseases -- 42. Dynamic and Multi-phase Contrast-enhanced CT Scan -- 43. Patient-specific 3D printing in Liver Disease -- 44. Dynamic Contrtast-Enhanced Ultrasonography of the Liver -- 45. Ultrasound Elastography -- 46. MR Elastography and Functional MRI of the Liver -- 47. Dynamic Contrast-enhanced MR Imaging -- 48. Transient elastography in chronic liver diseases -- 49. Portal Venography -- 50. Minilaparoscopy and Conventional Laparoscopy -- Part III: Treatment -- 51. Medical Nutrition Therapy in Liver Disease -- 52. Molecular Targets in Liver Disease -- 53. Specific Medications for Chronic Viral Hepatitis -- 54. Portal Vein Embolization (PVE) and Partial Transileocolic PVE with Associating Liver Partition and Portal Vein Ligation for Staged Hepatectomy—Beyond the Limitations of PVE -- 55. Endoscopic and Pharmacological Treatment of Esophageal Varices -- 56. Procedure for Gastric Variceal Bleeding - From BRTO to PARTO to CARTO, 3 Decades of Progress -- 57. Endoscopy and endoscopic ultrasound for the evaluation and treatment of gastric and ectopic varices -- 58. Portacaval Shunting for Portal Hypertension -- 59. Systemic Therapy of Advanced Liver Cancer -- 60. Embolization Therapy for Liver Cancer -- 61. Ablation of Hepatocellular Carcinoma -- 62. Laparoscopic Liver Resection -- 63. New locoregional approaches to treat liver cancer -- 64. Hepatic Encephalopathy -- 65. Management of ascites -- 66. Extracorporeal Non Cellular Liver Assisted Devices -- 67. Extracorporeal Cellular Liver Assisted Devices -- 68. Liver Transplantation for Acute and Chronic Liver Failure -- 69. Pre and Post Surgical Complications of Liver Transplantation -- 70. Anesthesia in Liver Transplantation -- 71. Surgery in Liver Disease -- 72. Robotic Liver Surgery -- 73. Cardiac surgery risks in liver dysfunction -- 74. Future Approaches in Liver Disorders: Regenerative Medicine.
- Format
- e-Book
- Location
- Online
Evidence-Based Critical Care : A Case Study Approach
https://libcat.nshealth.ca/en/permalink/provcat45378
Robert C. Hyzy, Jakob McSparron, editors.
(Second edition)
--Cham:
Springer
, c2020.
- Available Online
- View e-Book
- Location
- Online
This extensively updated textbook comprehensively reviews the latest developments in evidence-based critical care. Topics are covered in a case study format with an emphasis on the principles of diagnosis and therapy. Each topic is covered using a variety of case studies and features a case vignette, clinical question and an additional discussion section to clarify areas of particular importance. Topics including cytokine release syndrome, sympathomimetic overdose and palliative care in the int…
- Available Online
- View e-Book
- Other Authors
- Hyzy, Robert C.
- McSparron, Jakob
- Responsibility
- Robert C. Hyzy, Jakob McSparron, editors
- Edition
- Second edition
- Place of Publication
- Cham
- Publisher
- Springer
- Date of Publication
- c2020
- Physical Description
- 1 online resource (xv, 842 p.) : 251 illus., 148 illus. in color
- ISBN
- 9783030267100
- 9783030267094 (Print ed.)
- 9783030267117 (Print ed.)
- Subjects (MeSH)
- Critical Care
- Specialty
- Critical Care
- Abstract
- This extensively updated textbook comprehensively reviews the latest developments in evidence-based critical care. Topics are covered in a case study format with an emphasis on the principles of diagnosis and therapy. Each topic is covered using a variety of case studies and features a case vignette, clinical question and an additional discussion section to clarify areas of particular importance. Topics including cytokine release syndrome, sympathomimetic overdose and palliative care in the intensive care unit have been extensively revised, while new sections focusing on neuromuscular disease and subarachnoid hemorrhages have been added. Evidence-Based Critical Care, 2nd edition is a critical resource for critical care practitioners, fellows, residents; allied health professionals and medical students who wish to expand their knowledge within critical care. The case study-based approach taken in the textbook makes this an ideal resource for those preparing for board examinations.
- Contents
- Sympathomimetic overdose (designer drugs) -- Cardiac Arrest Management -- Beta blocker overdose -- Post- Cardiac Arrest Management -- Undifferentiated Shock -- Hypovolemic Shock and Massive Transfusion -- Acute Respiratory Failure -- Encephalitis -- Hyperkalemia NIV Implementation and Intubation -- Subarachnoid Hemorrhages -- Diagnosis and Management of Tricyclic Antidepressant Ingestion -- Hypernatremia -- Management of Calcium Channel Blocker Poisoning -- ICU Care Delivery and Medical Ethics -- Diagnosis and Management of Ethylene Glycol Ingestion -- Accidental Hypothermia -- Management of Cardiogenic Shock -- Management of Acute Heart Failure -- Management of Acute Coronary Syndrome -- Complications of Myocardial Infarction -- Management of Cardiac Tamponade -- Hypertensive Crises -- Atrial Fibrillation and Other Supraventricular Tachycardias -- Ventricular Arrhythmias -- Management of Acute Aortic Syndromes -- Management of Endocarditis -- Community Acquired Pneumonia -- Management of Acute Respiratory Distress Syndrome -- Acute Exacerbation of COPD: Non-Invasive Positive Pressure Ventilation -- Management of Status Asthmaticus -- Immunocompromised Pneumonia -- Venous Thromboembolism in the Intensive Care Unit -- Massive Hemoptysis -- Sedation and Delirium -- Prolonged Mechanical Ventilation -- Complications of trach -- Ventilator-Associated Pneumonia and Other Complications -- Respiratory Failure in a Patient with Idiopathic Pulmonary Fibrosis -- Weaning from Mechanical Ventilation -- The Post-Intensive Care Syndrome -- Management of Decompensated Right Ventricular Failure in the Intensive Care Unit -- Multi-disciplinary care/communication in the ICU -- Palliative care in ICU -- Family involvement in ICU -- Diffuse Alveolar Hemorrhage -- Acute Stroke Emergency Management -- Bacterial Meningitis in the ICU -- Management of Intracerebral Hemorrhage -- Status Epilepticus -- Neuroleptic Malignant Syndrome -- Traumatic Brain Injury -- Management of Anoxic Brain Injury -- Traditional and Novel Tools for Diagnosis of Acute Kidney Injury -- Management of Acute Kidney Injury -- Rhabdomyolysis -- Hyponatremia -- Management of Severe Hyponatremia and SIADH -- Diabetic Ketoacidosis -- Thyroid Storm -- Adrenal Insufficiency -- Management of Hyperglycemic Hyperosmolar Syndrome -- Management of Myxedema Coma -- Urosepsis -- Management of Sepsis and Septic Shock -- Invasive Aspergillus -- Management of Strongyloides Hyperinfection Syndrome -- Treatment of Viral Hemorrhagic Fever in a Well-Resourced Environment -- Management of Severe Malaria -- Dengue -- Chikungunya -- Leptospirosis -- Management of Acute Upper Gastrointestinal Hemorrhage -- Variceal Hemorrhage -- Acute Pancreatitis -- Management of Acute Liver Failure -- Acute Lower Gastrointestinal Bleeding -- Diagnosis and Management of Clostridium Difficile Infection (CDI) -- Principles of Nutrition in the Critically Ill Patient -- Spontaneous Bacterial Peritonitis -- ICU Management of the Patient with Alcoholic Liver Disease -- Diagnosis and Management of Thrombotic -- Thrombocytopenic Purpura -- Acute Leukemia Presentation with DIC -- Disseminated Intravascular Coagulation -- Hemophagocytic Lymphohistiocytosis -- ICU Complications of Hematopoietic Stem Cell -- Transplantation Including Graft vs. Host Disease -- Tumor Lysis Syndrome -- Management of Hyperviscosity Syndromes -- Thoracic Trauma -- Blunt Abdominal Trauma -- Oncologic emergencies -- Abdominal Sepsis and Complicated Intraabdominal Infection -- Intestinal Obstruction: Small and Large Bowel -- Management of Acute Compartment Syndrome -- Extracorporeal Membrane Oxygenation (ECMO) and Extracorporeal CO2 Removal (ECCO2R) -- Coagulopathy Management of Acute Thermal Injury -- Acute Arterial Ischemia -- Management of Necrotizing Soft Tissue Infection -- Cytokine release syndrome -- Biliary Infections -- Peripartum Cardiomyopathy -- Obstetric haemorrhage -- Management of Amniotic Fluid Embolism -- Respiratory Diseases of Pregnancy -- Preeclampsia, Eclampsia and HELLP Syndrome -- Management of Severe Skin Eruptions -- Management of Alcohol Withdrawal Syndromes -- End of Life Care in the ICU -- Neuromuscular Disease.
- Format
- e-Book
- Publication Type
- Case Reports
- Location
- Online
NAFLD and NASH : Biomarkers in Detection, Diagnosis and Monitoring
https://libcat.nshealth.ca/en/permalink/provcat45509
Manuel Romero-Gomez, editor.
--Cham:
Springer
, c2020.
- Available Online
- View e-Book
- Location
- Online
This book provides a comprehensive overview of the diagnosis and management of Non-alcoholic Fatty Liver Disease (NAFLD) and Non-Alcoholic Steatohepatis (NASH). Basic principles of disease progression, the genetic and nutritional basis of NAFLD and NASH are explained along with the proteomic principles underlying biomarker development. Chapters cover both biochemical and imaging biomarkers used in elastrography and ultrasound and discuss how these are applicable to early diagnosis and monitorin…
- Available Online
- View e-Book
- Other Authors
- Romero-Gomez, Manuel
- Responsibility
- Manuel Romero-Gomez, editor
- Place of Publication
- Cham
- Publisher
- Springer
- Date of Publication
- c2020
- Physical Description
- 1 online resource (x, 236 p.) : 18 illus., 17 illus. in color
- ISBN
- 9783030371739
- 9783030371722 (Print ed.)
- 9783030371746 (Print ed.)
- 9783030371753 (Print ed.)
- Subjects (MeSH)
- Biomarkers - analysis
- Diagnostic Techniques and Procedures
- Fatty Liver - diagnosis
- Non-alcoholic Fatty Liver Disease - diagnosis
- Specialty
- Diagnosis
- Gastroenterology
- Molecular Medicine
- Abstract
- This book provides a comprehensive overview of the diagnosis and management of Non-alcoholic Fatty Liver Disease (NAFLD) and Non-Alcoholic Steatohepatis (NASH). Basic principles of disease progression, the genetic and nutritional basis of NAFLD and NASH are explained along with the proteomic principles underlying biomarker development. Chapters cover both biochemical and imaging biomarkers used in elastrography and ultrasound and discuss how these are applicable to early diagnosis and monitoring of NASH and NAFLD. This is a useful resource for hepatologists, primary care providers with an interest in metabolic disease, diabetologists and endocrinologists in their daily clinical practice.
- Contents
- 1. The Spectrum of NAFLD: From the Organ to the System -- 2. Detection of NAFLD/NASH in the General Population and in Primary Care Clinics -- 3. Genes and NAFLD/NASH Progression -- 4. Geometry of Nutrition: Nutrients and NAFLD Progression -- 5. Biomarkers in Pediatric NAFLD -- 6. Biochemical Biomarkers of NAFLD/NASH -- 7. Non-invasive Assessment of Non-alcoholic Fatty Liver Disease: Ultrasound and Transient Elastography -- 8. MR Based-Imaging Biomarkers in NAFLD/NASH -- 9. Extracellular Vesicles in Non-alcoholic Fatty Liver Disease: Key Players in Disease Pathogenesis and Promising Biomarker Tools -- 10. From Transcriptomic to Metabolomic in the Development of Biomarkers in NAFLD/NASH -- 11. HCC in Patients with NAFLD/NASH -- 12. Psychological Biomarker Profile in NAFLD/NASH with Advanced Fibrosis -- 13. Integrative Proposal for the Use of Biomarkers in Clinical Practice Management of NAFLD/NASH.
- Format
- e-Book
- Location
- Online
Non-Alcoholic Fatty Liver Disease : A 360-degree Overview
https://libcat.nshealth.ca/en/permalink/provcat45659
Elisabetta Bugianesi, editor.
--Cham:
Springer
, c2020.
- Available Online
- View e-Book
- Location
- Online
The goal of this book is to promote awareness of non-alcoholic fatty liver disease (NAFLD) – which is rapidly replacing viral hepatitis as the leading cause of chronic liver disease in Europe, North and South America and Asia – and to share the latest information on evolving approaches to diagnosis and treatment. The book offers a comprehensive overview of the current topics of interest in the field, and provides clinical guidance on NAFLD through a multidisciplinary approach based on the lates…
- Available Online
- View e-Book
- Other Authors
- Bugianesi, Elisabetta
- Responsibility
- Elisabetta Bugianesi, editor
- Place of Publication
- Cham
- Publisher
- Springer
- Date of Publication
- c2020
- Physical Description
- 1 online resource (x, 362 p.) : 45 illus., 41 illus. in color
- ISBN
- 9783319958286
- 9783319958279 (Print ed.)
- 9783319958293 (Print ed.)
- Subjects (MeSH)
- Non-alcoholic Fatty Liver Disease
- Specialty
- Gastroenterology
- Abstract
- The goal of this book is to promote awareness of non-alcoholic fatty liver disease (NAFLD) – which is rapidly replacing viral hepatitis as the leading cause of chronic liver disease in Europe, North and South America and Asia – and to share the latest information on evolving approaches to diagnosis and treatment. The book offers a comprehensive overview of the current topics of interest in the field, and provides clinical guidance on NAFLD through a multidisciplinary approach based on the latest scientific understanding of this multisystemic disease, involving the expertise of specialists including hepatologists, diabetologists, and cardiologists. The respective contributions address various aspects, including the newly released international guidelines, novel diagnostic modalities, and new experimental drugs. The work will appeal to a broad readership, from residents in internal medicine to specialists.
- Contents
- 1. Obesity and NAFLD: Same Problem? -- 2. The Burden of NAFLD Worldwide -- 3. Histopathology of Nonalcoholic Fatty Liver Disease -- 4. NAFLD and Insulin Resistance: A Multisystemic Disease -- 5. Etiopathogenesis of NAFLD: Diet, Gut, and NASH -- 6. Mechanisms of Fibrogenesis in NASH -- 7. The Natural History of NAFLD: Environmental vs. Genetic Risk Factors -- 8. NAFLD, Diabetes, and Other Endocrine Diseases: Clinical Implications -- 9. NAFLD and Cardiovascular and Cardiac Disease: Clinical Implications -- 10. NAFLD, Hepatocellular Carcinoma, and Extrahepatic Cancers -- 11. NAFLD in Children: Implication for the Future -- 12. Diagnostic Algorithm for the Identification of NAFLD in Primary Care -- 13. Non-invasive Diagnostic Approach to NASH: Biological Markers -- 14. Noninvasive Diagnostic Approach to NASH: Radiological Diagnostics -- 15. Dietary Approach to NAFLD -- 16. Physical Activity in NAFLD: What and How Much? -- 17. Pharmacological Options for NASH -- 18. Bariatric Surgery and NASH: A Feasible Option -- 19. Liver Transplantation and NAFLD/NASH.
- Format
- e-Book
- Location
- Online
Liver Failure : Acute and Acute on Chronic
https://libcat.nshealth.ca/en/permalink/provcat45993
Nikolaos Pyrsopoulos, editor.
--Cham:
Springer
, c2020.
- Available Online
- View e-Book
- Location
- Online
This book offers a comprehensive overview of liver failure including epidemiology, mechanism of the disease, and its clinical manifestations. The diagnosis of numerous types of liver disease leading to liver failure; with specific emphasis on the current and future treatment modalities including up-to-date and extensive information on liver transplantation. It provides the most up-to-date information on liver failure for clinicians, practitioners including GPs, scientists/researchers, postgradu…
- Available Online
- View e-Book
- Other Authors
- Pyrsopoulos, Nikolaos
- Responsibility
- Nikolaos Pyrsopoulos, editor
- Place of Publication
- Cham
- Publisher
- Springer
- Date of Publication
- c2020
- Physical Description
- 1 online resource (viii, 373 p.) : 46 illus., 39 illus. in color
- ISBN
- 9783030509835
- 9783030509828 (Print ed.)
- 9783030509842 (Print ed.)
- 9783030509859 (Print ed.)
- Subjects (MeSH)
- Acute-On-Chronic Liver Failure - etiology
- Acute-On-Chronic Liver Failure - therapy
- Liver Failure, Acute - etiology
- Liver Failure, Acute - therapy
- Specialty
- Gastroenterology
- Abstract
- This book offers a comprehensive overview of liver failure including epidemiology, mechanism of the disease, and its clinical manifestations. The diagnosis of numerous types of liver disease leading to liver failure; with specific emphasis on the current and future treatment modalities including up-to-date and extensive information on liver transplantation. It provides the most up-to-date information on liver failure for clinicians, practitioners including GPs, scientists/researchers, postgraduates and allied health professionals. It features an overview of the relevant classification and epidemiologic aspects of acute liver failure along with a thorough review of the mechanisms associated with acute liver failure and multisystemic involvement. Detailed guidance is also provided on the latest treatment techniques including those available for liver transplantation and potential future approaches, enabling the reader to develop a detailed understanding of the topic. Liver Failure: Acute and Acute on Chronic provides a practically applicable guide to the epidemiology and management of liver failure. It features contributions from an outstanding panel of experts in hepatology, gastroenterology and surgery making it a vital up-to-date reference for trainee and practicing medical professionals in a variety of disciplines who encounter these patients.
- Contents
- 1. Classification and Epidemiologic Aspects of Acute and Acute on Chronic Liver Failure -- 2. Acute and Acute on Chronic Liver Failure: Mechanisms of Disease and Multisystemic Involvement -- 3. The Pathology of Acute and Acute on Chronic Liver Failure -- 4. Liver Regeneration in the Acute and Acute on Chronic Liver Failure Patient -- 5. Prognostic Models in Acute and Acute on Chronic Liver Failure -- 6. The Clinical Spectrum and Manifestations of Acute and Acute on Chronic Liver Failure -- 7. Non-Intensive Care Unit Management of Acute and Acute on Chronic Liver Failure -- 8. Management of Acute and Acute on Chronic Liver Failure in the Intensive Care Unit Setting -- 9. Viral Hepatitis B, C and D in ALF and ALF/CLD -- 10. Viral Hepatitis Non: B, C, D and Acute and Acute on Chronic Liver Failure -- 11. Drug-Induced Acute and Acute on Chronic Liver Failure -- 12. Acetaminophen syn. Paracetamol: Acute Liver Injury and Acute on Chronic Liver Failure with Case Analysis and Causality Assessment Using RUCAM -- 13. Non-viral or Drug-Induced Causes of Acute Liver Failure -- 14. Alcoholic Hepatitis and Alcohol-Related Acute on Chronic Liver Failure -- 15. Liver Transplantation for Acute and Acute on Chronic Liver Failure -- 16. Cellular and Non-Cellular Liver Assist Devices in Management of Acute and Acute on Chronic Liver Failure -- 17. Looking Past Orthotopic Liver Transplantation: A Review of Emerging Strategies for Managing Acute and Acute-on-Chronic Liver Failure.
- Format
- e-Book
- Location
- Online
Obesity : Pathogenesis, Diagnosis, and Treatment
https://libcat.nshealth.ca/en/permalink/provcat44065
Paolo Sbraccia, Nicholas Finer, editors.
--Cham:
Springer
, c2019.
- Available Online
- View e-Book
- Location
- Online
This book presents the latest advances in our understanding of the pathophysiologic basis that induces the chronic positive energy balance necessary to progressively store excessive amounts of fat mass. It highlights the clinical complications of obesity, while also focusing on the major scientific advances that have highlighted the role of genetics, adipose tissue endocrinology and the environment in the mechanisms and causes of obesity. Particular attention is given to the consequences of obe…
- Available Online
- View e-Book
- Other Authors
- Sbraccia, Paolo
- Finer, Nicholas
- Responsibility
- Paolo Sbraccia, Nicholas Finer, editors
- Place of Publication
- Cham
- Publisher
- Springer
- Date of Publication
- c2019
- Physical Description
- 1 online resource (xv, 440 p.) : 66 illus., 49 illus. in color
- Series
- Endocrinology
- Series Title
- Springer reference
- Endocrinology
- ISBN
- 9783319469331
- 9783319469324 (Print ed.)
- ISSN
- 2510-1927
- Subjects (MeSH)
- Obesity - physiopathology
- Obesity - complications
- Obesity - therapy
- Specialty
- Bariatric Medicine
- Notes
- "eReference".
- Abstract
- This book presents the latest advances in our understanding of the pathophysiologic basis that induces the chronic positive energy balance necessary to progressively store excessive amounts of fat mass. It highlights the clinical complications of obesity, while also focusing on the major scientific advances that have highlighted the role of genetics, adipose tissue endocrinology and the environment in the mechanisms and causes of obesity. Particular attention is given to the consequences of obesity, including an ever-increasing number of other diseases such as type 2 diabetes, cardiovascular diseases and cancer, as well as conditions such as arthropathy, asthma, non-alcoholic liver disease, and dementia. Increasingly recognized uniting causes highlight the role of systemic, local and paracrine actions of adipocytokines in causing inflammation. As we come to better understand how hypothalamic control of energy balance is influenced by endocrine signaling from the gut and adipose tissue, it paves the way for new therapeutic targets and a resurgence of pharmacological and surgical approaches to treatment. Written by respected experts in the field, this volume is intended as a major reference source for endocrinologists, nutritionists, basic and clinical scientists alike.
- Contents
- 1. Epidemiology of Obesity -- 2. Neuroendocrinology of Energy Balance -- 3. The Adipose Organ -- 4. Roles of Gut Hormones in the Regulation of Food Intake and Body Weight -- 5. Obesity Pathogenesis -- 6. The Microbiota and Energy Balance -- 7. Eating Disorders -- 8. Clinical Assessment of the Patient with Overweight or Obesity -- 9. Obesity and NAFLD -- 10. Obesity and Type 2 Diabetes -- 11. Obesity, Hypertension, and Dyslipidemia -- 12. Obesity and Obstructive Sleep Apnea Syndrome -- 13. Impact of Obesity on Cardiovascular Disease -- 14. Obesity in Children and Adolescents -- 15. Exercise in the Treatment of Obesity -- 16. Psychological Approaches in the Treatment of Obesity -- 17. Surgical Approaches in the Treatment of Obesity -- 18. Medications Indicated for Chronic Weight Management -- 19. An Integrated View of Treatment Options Available for Obesity.
- Format
- e-Book
- Location
- Online
Pediatric Hepatology and Liver Transplantation
https://libcat.nshealth.ca/en/permalink/provcat44266
Lorenzo D'Antiga, editor.
--Cham:
Springer
, 2019.
- Available Online
- View e-Book
- Location
- Online
This book is the first to provide balanced examination of both pediatric liver disease and liver transplantation – two topics that are inherently related, given that most chronic liver disorders eventually require organ replacement. The different forms of liver disease encountered in the pediatric age group are first discussed in a series of disease-specific chapters that have a reader-friendly, uniform structure covering pathophysiology, diagnostic and treatment algorithms, clinical cases, and…
- Available Online
- View e-Book
- Other Authors
- D'Antiga, Lorenzo
- Responsibility
- Lorenzo D'Antiga, editor
- Place of Publication
- Cham
- Publisher
- Springer
- Date of Publication
- 2019
- Physical Description
- 1 online resource (xix, 829 p.) : 327 illus., 259 illus. in color
- ISBN
- 9783319964003
- 9783319963990 (Print ed.)
- 9783319964010 (Print ed.)
- Subjects (MeSH)
- Child
- Liver Diseases
- Liver Transplantation
- Specialty
- Gastroenterology
- Pediatrics
- Transplantation
- Abstract
- This book is the first to provide balanced examination of both pediatric liver disease and liver transplantation – two topics that are inherently related, given that most chronic liver disorders eventually require organ replacement. The different forms of liver disease encountered in the pediatric age group are first discussed in a series of disease-specific chapters that have a reader-friendly, uniform structure covering pathophysiology, diagnostic and treatment algorithms, clinical cases, and transition to adult care. Key topics in the field of liver transplantation are then addressed. Examples include indications and contraindications, surgical techniques and complications, immunosuppression, in pediatric liver transplantation, acute and chronic rejection and allograft dysfunction, and CMV and EBV infection in transplant recipients, long-term graft injury and tolerance. A section on pediatric hepatology across the world includes chapters presenting the features and management of pediatric liver disease in South-America, Africa and Asia. A closing section considers what the future holds for pediatric liver disease and its management, including novel genetic testing, cell therapy and gene therapy. Pediatric Hepatology and Liver Transplantation will be of value for a range of practitioners, from residents making their first approach to pediatric liver disease through to specialists working in transplantation centers.
- Contents
- 1. Liver disease in paediatric medicine: An overview -- 2. Anatomy and histology of the liver and biliary tract -- 3. Laboratory evaluation of hepatobiliary disease -- 4. Diagnostic and interventional radiology -- 5. Practical approach to the jaundiced infant -- 6. Biliary atresia and other disorders of the extrahepatic biliary tree -- 7. Acute liver failure -- 8. Viral hepatitis -- 9. Autoimmune liver disease -- 10. Fibrocystic liver disease -- 11. Gallstone disease -- 12. Genetic and familial cholestasis -- 13. Wilson disease -- 14. Liver disease in cystic fibrosis -- 15. Inherited metabolic disorders -- 16. Non-alcoholic fatty liver disease and steatohepatitis in children -- 17. Complications of cirrhosis -- 18. Cirrhotic and non-cirrhotic portal hypertension -- 19. Vascular liver disease -- 20. Liver tumours and nodular lesions -- 21. The liver in systemic illness -- 22. Nutrition and liver disease -- 23. Intensive care management of the child with liver disease -- 24. Peculiarities of common and uncommon indications to liver transplantation -- 25. Organs availability and allocation -- 26. Surgical Techniques -- 27. Living donor liver transplantation -- 28. Listing for transplantation, postoperative management and f/up protocol -- 29. Surgical complications -- 30. Immunosuppression in paediatric liver transplantation -- 31. Pathology of liver allograft dysfunction -- 32. Chronic rejection and late allograft hepatitis -- 33. CMV and EBV infection and disease -- 34. Liver transplantation for inborn errors of metabolism -- 35. Immune tolerance following liver transplantation -- 36. Long-term outcome and transition to adult care -- 37. Neurodevelopment and health related quality of life of the transplanted child -- 38. Pediatric liver Disease in Latin America -- 39. Liver disease in the African continent -- 40. Liver disease in the Asian continent -- 41. Next generation sequencing for the diagnosis of monogenic liver disease -- 42. Cell therapy for acute and chronic liver disease -- 43. Gene therapy in paediatric liver disease.
- Format
- e-Book
- Location
- Online
Translational Research Methods in Diabetes, Obesity, and Nonalcoholic Fatty Liver Disease : A Focus on Early Phase Clinical Drug Development
https://libcat.nshealth.ca/en/permalink/provcat44329
Andrew J. Krentz, Christian Weyer, Marcus Hompesch, editors.
(Second edition)
--Cham:
Springer
, 2019.
- Available Online
- View e-Book
- Location
- Online
This book aims to aid the selection of the most appropriate methods for use in early phase (1 and 2) clinical studies of new drugs for diabetes, obesity, non-alcoholic fatty liver disease (NAFLD) and related cardiometabolic disorders. Clinical research methods to assess the pharmacokinetics and pharmacodynamics of new diabetes drugs, e.g. the euglycemic clamp technique, have become well-established in proof-of-mechanism studies. However, selection of the most appropriate techniques is by no mea…
- Available Online
- View e-Book
- Other Authors
- Krentz, Andrew J.
- Weyer, Christian
- Hompesch, Marcus
- Responsibility
- Andrew J. Krentz, Christian Weyer, Marcus Hompesch, editors
- Edition
- Second edition
- Place of Publication
- Cham
- Publisher
- Springer
- Date of Publication
- 2019
- Physical Description
- 1 online resource (xi, 556 p.) : 115 illus., 59 illus. in color
- ISBN
- 9783030117481
- 9783030117474 (Print ed.)
- 9783030117498 (Print ed.)
- Subjects (MeSH)
- Diabetes Mellitus
- Drug Development
- Metabolic Diseases
- Non-alcoholic Fatty Liver Disease
- Pharmaceutical Research
- Translational Medical Research
- Specialty
- Diabetes Mellitus
- Pharmacology
- Physiology
- Abstract
- This book aims to aid the selection of the most appropriate methods for use in early phase (1 and 2) clinical studies of new drugs for diabetes, obesity, non-alcoholic fatty liver disease (NAFLD) and related cardiometabolic disorders. Clinical research methods to assess the pharmacokinetics and pharmacodynamics of new diabetes drugs, e.g. the euglycemic clamp technique, have become well-established in proof-of-mechanism studies. However, selection of the most appropriate techniques is by no means straightforward. Moreover, the application of such methods must conform to the regulatory requirements for new drugs. This book discusses the need for new pharmacotherapies for diabetes, obesity and NAFLD and the molecular targets of drugs currently in development. Emerging technologies including functional imaging, circulating biomarkers and omics are considered together with practical and ethical issues pertaining to early phase clinical trials in subjects with cardiometabolic disorders. Translational Research Methods in Diabetes, Obesity, and Non-Alcoholic Fatty Liver Disease is of interest to biomedical scientists, pharmacologists, academics involved in metabolic research and clinicians practicing in these specialties.
- Contents
- Part I. Review of Clinical Investigative Methods -- 1. Quantification of Insulin Action in Human Subjects -- 2. Assessment of Islet Alpha- and Beta-Cell Function -- 3. Pharmacokinetic and Pharmacodynamic Assessment of Novel and Biosimilar Insulins -- 4. Measurement of Energy Expenditure -- 5. Quantifying Appetite and Satiety -- 6. Non-invasive Quantitative Magnetic Resonance Imaging and Spectroscopic Biomarkers in Nonalcoholic Fatty Liver Disease and Other Cardiometabolic Diseases Associated with Ectopic Fat Deposition -- 7. Structural and Functional Imaging of Muscle, Heart, Endocrine Pancreas and Kidneys in Cardiometabolic Drug Development -- 8. Positron Emission Tomography and Computed Tomography Measurement of Brown Fat Thermal Activation: Key Tool for Developing Novel Pharmacotherapeutics for Obesity and Diabetes -- 9. Isotopic Tracers for the Measurement of Metabolic Flux Rates -- 10. Role of Tissue Biopsy in Drug Development for Nonalcoholic Fatty Liver Disease and Other Metabolic Disorders -- 11. Utility of Invasive and Non-invasive Cardiovascular Research Methodologies in Drug Development for Diabetes, Obesity and NAFLD/NASH -- 12. Omics: Potential Role in Early Phase Drug Development -- Part II. Preclinical Drug Development and Transitioning to Clinical Studies -- 13. Peptide Drug Design for Diabetes and Related Metabolic Diseases -- 14. Animal Models of Type 2 Diabetes, Obesity and Nonalcoholic Steatohepatitis – Clinical Translatability and Applicability in Preclinical Drug Development -- 15. Drug Development for Diabetes Mellitus: Beyond Hemoglobin A1c -- 16. Emerging Circulating Biomarkers for The Diagnosis and Assessment of Treatment Responses in Patients with Hepatic Fat Accumulation, Nash and Liver Fibrosis -- 17. Quantitative Approaches in Translational Cardiometabolic Research: An Overview -- 18. Transitioning from Preclinical to Clinical Drug Development -- 19. Regulatory Considerations for Early Clinical Development of Drugs for Diabetes, Obesity, Nonalcoholic Steatohepatitis (NASH) and Other Cardiometabolic Disorders -- 20. Early Phase Metabolic Research with Reference to Special Populations.
- Format
- e-Book
- Location
- Online
The Diabetes Textbook : Clinical Principles, Patient Management and Public Health Issues
https://libcat.nshealth.ca/en/permalink/provcat44446
Joel Rodriguez-Saldana, editor.
--Cham:
Springer
, c2019.
- Available Online
- View e-Book
- Location
- Online
Diabetes has become a worldwide health problem, the global estimated prevalence approaches ten percent and the burden of this disease in terms of morbidity and mortality is unprecedented. The advances acquired through the knowledge of the mechanisms of the disease and the variety of therapeutic approaches contrast with the inability of private and public health systems in underdeveloped and even developed countries to achieve the goals of treatment. This paradox has been described in many sourc…
- Available Online
- View e-Book
- Other Authors
- Rodriguez-Saldana, Joel
- Responsibility
- Joel Rodriguez-Saldana, editor
- Place of Publication
- Cham
- Publisher
- Springer
- Date of Publication
- c2019
- Physical Description
- 1 online resource (xx, 1040 p.) : 212 illus., 183 illus. in color
- ISBN
- 9783030118150
- 9783030118143 (Print ed.)
- 9783030118167 (Print ed.)
- Subjects (MeSH)
- Diabetes Mellitus
- Specialty
- Diabetes Mellitus
- Abstract
- Diabetes has become a worldwide health problem, the global estimated prevalence approaches ten percent and the burden of this disease in terms of morbidity and mortality is unprecedented. The advances acquired through the knowledge of the mechanisms of the disease and the variety of therapeutic approaches contrast with the inability of private and public health systems in underdeveloped and even developed countries to achieve the goals of treatment. This paradox has been described in many sources: the surge of scientific advances contrast with an unprecedented amount of human suffering. Thus, a patient centered and an evidence based approach with the capacity to produce measurable clinical and economic outcomes is required. The purpose of this textbook is multiple: to offer a comprehensive resource covering all aspects of outpatient management; to address diabetes as a health problem from an epidemiological, economic and clinical perspective; to discuss the role of social determinants of health on the worldwide increase in diabetes; to highlight the challenges and obstacles in providing adequate care; and to outline a multidisciplinary approach to management in which medical visits retain their importance as part of a team comprising the patient, his or her family and a multidisciplinary group of health professionals who are able to move beyond the traditional approach of diabetes as a disease and greatly improve outcomes.
- Contents
- Preface: A New Disease? -- Part I. Magnitude of the Problem from an Individual and Social Context -- The Dynamics of Diabetes Prevalence, Morbidity and Mortality -- Economic Costs, from Individuals to Health Systems: Evidence from a Middle Income Country -- The Ecological Approach to Self-Care in Diabetes -- Social Determinants of Health and Diabetes Outcomes -- Part II. Diagnosis, Classifications and Mechanisms of Disease -- Definition, Diagnostic Criteria, Screening, Diagnosis and Classification of Diabetes and Categories of Glucose Intolerance -- Pathophysiology of Type 1 Diabetes -- Pathophysiology of Type 2 Diabetes -- Genetic Determinants of Type 2 Diabetes -- Gene Expression Modifications in Type 2 Diabetes -- The Immune System and Inflammation in Type 2 Diabetes -- Dysfunction and Death of Pancreatic Beta Cells in Type 2 Diabetes -- Obesity in the Pathophysiology of Diabetes -- Pathogenesis of Gestational Diabetes -- Non-Alcoholic Fatty Liver in the Pathogenesis of Diabetes -- Part III. Global Experiences in Diabetes Care -- Diabetes Management in Europe -- Diabetes Management in Asia -- Diabetes Management in the United States -- Diabetes Management in Africa -- Part IV. Basic Components of Management: Patient Centeredness, Evidence-Based Medicine and Outcomes. Challenges for Implementation -- The Patient-Centered Medical Home, Primary Care and Diabetes -- Outpatient Diabetes Management and the Chronic Care Model -- Clinical Practice Guidelines for Diabetes -- Quality of Diabetes Care: Measuring Clinical Impact, Cost Effectiveness and Patient Experience of Care -- Clinical Inertia in Diabetes: The Role of Physicians -- Patient Adherence in Diabetes: Challenges, Myths and Realities -- Part V. Resources of Support for Persons with Diabetes -- Challenges and Opportunities in Diabetes Education -- Diabetes and Mental Health: From Distress to Depression -- Tools of Self-Care: Self-Monitoring of Blood Glucose and Tele-health Resources -- Continuous Glucose Monitoring and Clinical Decision Making -- Diabetes and Lifestyle Medicine -- Evidence and Implementation of Nutrition Therapy in Persons with Diabetes -- Evidence and Implementation of Physical Activity and Exercise -- Part VI. Drug Therapy -- The “Old” Oral Antidiabetics -- Incretin Therapies: Current Use and Emerging Possibilities -- Sodium Glucose Transporter Inhibitors -- Insulin in Outpatient Diabetes Management -- Insulin Pump Therapy -- Part VII. Cardiovascular Risk Factors -- Diabetes and Hypertension -- Diabetes and Atherogenic Dyslipidemia -- Diabetes and Obesity -- Diabetes and Smoking -- Part VIII.Acute Complications -- Hyperglycemic Crisis: Diabetic (ketoacidosis (DKA) -- Hypoglycemia: Diagnosis, Management and Prevention -- Inpatient Management of Diabetes and Hyperglycemia -- Diabetes and Infection -- Part IX. Chronic Complications -- Diabetes and Stroke: The Role of Glucose Regulation -- Diabetes and Peripheral Artery Disease -- Biochemical and Molecular Mechanisms of Vascular Complications in Diabetes -- Ophthalmologic Eye Disease -- Diabetes and Oral Health -- Renal Disease in Diabetes -- Peripheral Diabetic Neuropathies -- Diabetic Cardiac Autonomic Neuropathy -- Autonomic Visceral Neuropathy and Gastrointestinal Disorders -- Urologic Complications and Sexual Dysfunction -- Musculoskeletal Complications of Diabetes -- Diabetes and the Skin -- Foot Complications -- Diabetes and Cancer -- Part X. Diabetes in Special Populations -- Children and Adolescents -- Pregnancy: Pregestational and Gestational Management -- The Elderly with Diabetes -- Part XI. Diabetes Prevention -- Prevention of Type 2 Diabetes: Evidence and Challenges -- Part XII. Novel Therapeutic Approaches: Evidence-Based and Others -- Insulin Pumps and Closed Loop Systems and the Artificial Pancreas -- Unproven Therapies for Diabetes.
- Format
- e-Book
- Location
- Online
Alcoholic/Non-Alcoholic Digestive Diseases
https://libcat.nshealth.ca/en/permalink/provcat44462
Hitoshi Yoshiji, Kosuke Kaji, editors.
--Singapore:
Springer
, c2019.
- Available Online
- View e-Book
- Location
- Online
This book describes the latest advances concerning the molecular mechanisms of and therapeutic strategies for alcohol- and non-alcohol-related digestive diseases. Alcohol abuse causes not only liver injury but can harm various organs, resulting in esophageal and colorectal cancers, GERD, pancreatitis, etc. Similar to alcoholic abuse, metabolic syndrome based on obesity and diabetes is also strongly associated with the development of various digestive diseases. Although these diseases may be dif…
- Available Online
- View e-Book
- Other Authors
- Yoshiji, Hitoshi
- Kaji, Kosuke
- Responsibility
- Hitoshi Yoshiji, Kosuke Kaji, editors
- Place of Publication
- Singapore
- Publisher
- Springer
- Date of Publication
- c2019
- Physical Description
- 1 online resource (viii, 166 p.) : 25 illus., 19 illus. in color
- ISBN
- 9789811314650
- 9789811314643 (Print ed.)
- 9789811314667 (Print ed.)
- Subjects (MeSH)
- Alcohol-Induced Disorders
- Gastrointestinal Diseases - etiology
- Liver Diseases - etiology
- Pancreatic Diseases - etiology
- Specialty
- Gastroenterology
- Abstract
- This book describes the latest advances concerning the molecular mechanisms of and therapeutic strategies for alcohol- and non-alcohol-related digestive diseases. Alcohol abuse causes not only liver injury but can harm various organs, resulting in esophageal and colorectal cancers, GERD, pancreatitis, etc. Similar to alcoholic abuse, metabolic syndrome based on obesity and diabetes is also strongly associated with the development of various digestive diseases. Although these diseases may be differentiated by the presence or absence of alcohol intake, the pathologic findings and pathogenesis reveal a number of similarities. This volume covers clinical and basic approaches for esophageal, gastric, hepatic, colorectal and pancreatic diseases associated with alcohol abuse and metabolic syndrome; further, it discusses the roles of microbiota, oxidative stress, and apoptosis, the critical factors causing alcoholic and metabolic digestive diseases. Also, it showcases new pathological and therapeutic perspectives in gastric and pancreatic cancers. Alcoholic/Non-Alcoholic Digestive Diseases will provide invaluable information for doctors specializing in gastroenterology and hepatology and researchers seeking new research on digestive diseases based on alcohol consumption and obesity.
- Contents
- Part I. Alcoholic/Non-Alcoholic Gastrointestinal Diseases -- 1. Alcohol-Induced DNA Injury in Esophageal Squamous Cell Carcinoma -- 2. Gastroesophageal Reflux Diseases and Lifestyle Factors -- 3. Post Helicobacter pylori Gastric Diseases -- 4. New Perspectives in Gastric Cancer: Helicobacter pylori-Uninfected Pure Signet Ring Cell Carcinoma -- 5. Role of Alcohol and Metabolic Diseases in Colorectal Carcinogenesis -- Part II. Alcoholic/Non-Alcoholic Liver Diseases -- 6. Extracellular Vesicles in Alcoholic Liver Injury -- 7. Diabetes in Liver Disease -- 8. Obesity and Hepatocarcinogenesis -- 9. Microbiota in Non-alcoholic Liver Disease -- 10. Role of Oxidative Stress in Alcoholic/Non-Alcoholic Liver Diseases -- 11. Role of Apoptosis in Liver Diseases -- Part III. Alcoholic/Non-Alcoholic Pancreatic Diseases -- 12. Genetics of Pancreatitis -- 13. New Perspective in Pancreatic Cancer.
- Format
- e-Book
- Location
- Online
Diagnosis of Liver Disease
https://libcat.nshealth.ca/en/permalink/provcat44641
Etsuko Hashimoto, Paul Y. Kwo, Arief A. Suriawinata, Wilson M.S. Tsui, Masaki Iwai, editors.
(Second edition)
--Singapore:
Springer
, c2019.
- Available Online
- View e-Book
- Location
- Online
This book guides practitioners in the assessment of patients with a liver problem. The emphasis is on the role of macro- and microscopic pathology in elucidating pathogenesis as well as identifying confounding features of image findings that may lead to a more elaborate differential diagnosis. If appropriate, the role of light and electron microscopic examination, along with the role of specific stains and molecular techniques, is illustrated. In addition, the concept of each liver disease is s…
- Available Online
- View e-Book
- Responsibility
- Etsuko Hashimoto, Paul Y. Kwo, Arief A. Suriawinata, Wilson M.S. Tsui, Masaki Iwai, editors
- Edition
- Second edition
- Place of Publication
- Singapore
- Publisher
- Springer
- Date of Publication
- c2019
- Physical Description
- 1 online resource (xvi, 304 p.) : 336 illus., 248 illus. in color
- ISBN
- 9789811368066
- 9789811368059 (Print ed.)
- 9789811368073 (Print ed.)
- 9789811368080 (Print ed.)
- Subjects (MeSH)
- Liver Diseases - diagnosis
- Specialty
- Gastroenterology
- Abstract
- This book guides practitioners in the assessment of patients with a liver problem. The emphasis is on the role of macro- and microscopic pathology in elucidating pathogenesis as well as identifying confounding features of image findings that may lead to a more elaborate differential diagnosis. If appropriate, the role of light and electron microscopic examination, along with the role of specific stains and molecular techniques, is illustrated. In addition, the concept of each liver disease is summarized briefly and its up-to-data is provided, and unresolved problems in diagnosis, treatment, and pathogenesis are clearly described. The approach in this book is a practical one with a focus on the evaluation of illustrative cases, simultaneously demonstrating cross-sectional images (ultrasonography, computed tomography, magnetic resonance imaging, and angiography), pathological findings, and peritoneoscopic images. The diagnosis and therapy are summed up in helpful tables, and association of clinical manifestations with image analysis and pathological findings is shown to be important in differential diagnosis and treatment. With the authors comprising internationally renowned experts, this book will serve as a useful source of information for medical students, physicians, internists, hepatologists, gastroenterologists, radiologists, and pathologists worldwide.
- Contents
- 1. Anatomy and Function -- 2. Laboratory Tests in Liver Diseases -- 3. Acute Hepatitis -- 4. Acute Liver Failure -- 5. Chronic Hepatitis -- 6. Liver Cirrhosis -- 7. Alcoholic Liver Disease and Nonalcoholic Fatty Liver Disease / Nonalcoholic Steatohepatitis -- 8. Drug-induced Liver Injury -- 9. Autoimmune Liver Disease -- 10. Developmental Abnormalities of the Bile Duct & Foregut -- 11. Vascular Disorders in Liver -- 12. Metabolic Disorders in Liver -- 13. Hyperbilirubinemia -- 14. Granulomatous Liver Diseases -- 15. Liver Disorders in Systemic Diseases -- 16. Liver Tumor I: Benign Tumors and Tumor-Like Lesions -- 17. Liver Tumors II: Malignant Tumors of the Liver -- 18. Metastatic Liver Tumors -- 19. Liver Pathology in Transplantation -- 20. Peritoneal Diseases.
- Format
- e-Book
- Location
- Online
Obesity : Pathogenesis, Diagnosis, and Treatment
https://libcat.nshealth.ca/en/permalink/provcat44573
edited by Paolo Sbraccia, Nicholas Finer.
--Cham:
Springer
, c2018.
- Available Online
- View e-Book
- Location
- Online
This book presents the latest advances in our understanding of the pathophysiologic basis that induces the chronic positive energy balance necessary to progressively store excessive amounts of fat mass. It highlights the clinical complications of obesity, while also focusing on the major scientific advances that have highlighted the role of genetics, adipose tissue endocrinology and the environment in the mechanisms and causes of obesity. Particular attention is given to the consequences of obe…
- Available Online
- View e-Book
- Other Authors
- Sbraccia, Paolo
- Finer, Nicholas
- Responsibility
- edited by Paolo Sbraccia, Nicholas Finer
- Place of Publication
- Cham
- Publisher
- Springer
- Date of Publication
- c2018
- Physical Description
- 1 online resource (x, 352 p.)
- Series Title
- Springer reference
- Endocrinology
- ISBN
- 9783319476858
- ISSN
- 2510-1927
- Subjects (MeSH)
- Obesity - complications
- Obesity - physiopathology
- Specialty
- Bariatric Medicine
- Notes
- "Living reference work."
- Abstract
- This book presents the latest advances in our understanding of the pathophysiologic basis that induces the chronic positive energy balance necessary to progressively store excessive amounts of fat mass. It highlights the clinical complications of obesity, while also focusing on the major scientific advances that have highlighted the role of genetics, adipose tissue endocrinology and the environment in the mechanisms and causes of obesity. Particular attention is given to the consequences of obesity, including an ever -increasing number of other diseases such as type 2 diabetes, cardiovascular diseases and cancer, as well as conditions such as arthropathy, asthma, non-alcoholic liver disease, and dementia. Increasingly recognized uniting causes highlight the role of systemic, local and paracrine actions of adipocytokines in causing inflammation. As we come to better understand how hypothalamic control of energy balance is influenced by endocrine signaling from the gut and adipose tissue, it paves the way for new therapeutic targets and a resurgence of pharmacological and surgical approaches to treatment. Written by respected experts in the field, this volume is intended as a major reference source for endocrinologists, nutritionists, basic and clinical scientists alike.
- Contents
- An Integrated View of Treatment Options Available for Obesity -- Clinical Assessment of the Patient with Overweight or Obesity -- Eating Disorders -- Epidemiology of Obesity -- Exercise in the Treatment of Obesity -- Impact of Obesity on Cardiovascular Disease -- Medications Indicated for Chronic Weight Management -- Neuroendocrinology of Energy Balance -- Obesity and NAFLD -- Obesity and Obstructive Sleep Apnea Syndrome -- Obesity and Type 2 Diabetes -- Obesity in Children and Adolescents -- Obesity Pathogenesis -- Obesity, Hypertension, and Dyslipidemia -- Psychological Approaches in the Treatment of Obesity -- Roles of Gut Hormones in the Regulation of Food Intake and Body Weight -- Surgical Approaches in the Treatment of Obesity -- The Adipose Organ -- The Microbiota and Energy Balance.
- Format
- e-Book
- Location
- Online
Essentials of Mini One Anastomosis Gastric Bypass
https://libcat.nshealth.ca/en/permalink/provcat42953
edited by Mervyn Deitel.
--Cham:
Springer
, c2018.
- Available Online
- View e-Book
- Location
- Online
This book indicates the technique and fine points of the mini- and one-anastomosis gastric bypass, and looks at the means of revising other operations related to it. The chapters discuss postoperative complications, treatment and requirements, postoperative diet and medications, the remarkable effects on the co-morbidities of morbid obesity, and the durability of the weight loss, as well as the improvement in the quality of life. Essentials of Mini One Anastomosis Gastric Bypass aims to help su…
- Available Online
- View e-Book
- Other Authors
- Deitel, Mervyn
- Responsibility
- edited by Mervyn Deitel
- Place of Publication
- Cham
- Publisher
- Springer
- Date of Publication
- c2018
- Physical Description
- 1 online resource (xv, 371 p.) : 176 illus., 166 illus. in color
- ISBN
- 9783319761770
- 9783319761763 (print ed.)
- 9783319761787 (print ed.)
- Subjects (MeSH)
- Gastric Bypass - methods
- Laparoscopy
- Obesity, Morbid - surgery
- Abstract
- This book indicates the technique and fine points of the mini- and one-anastomosis gastric bypass, and looks at the means of revising other operations related to it. The chapters discuss postoperative complications, treatment and requirements, postoperative diet and medications, the remarkable effects on the co-morbidities of morbid obesity, and the durability of the weight loss, as well as the improvement in the quality of life. Essentials of Mini One Anastomosis Gastric Bypass aims to help surgeons manage the difficulties encountered within this procedure and to help create improved practice.
- Contents
- A Brief History of Bariatric Surgery to the Present -- Understanding the Technique of MGB: Clearing the Confusion -- Physiology of the MGB: How it Works for Long-term Weight Loss -- Ten Crucial Steps for the MGB Operation -- The Ideal Length of the Jejunal Limb in MGB -- Perioperative Care in the MGB and Anesthetic Management -- Early Complications of the MGB Çô Prevention and Treatment -- Late Complications of the MGB—Prevention and Treatment -- Diet, Supplements and Medications after MGB. Nutritional Outcomes. Avoidance of Iron Deficiency. MGB in Vegetarians -- Patient Contraindications to Undergoing MGB -- Understanding the Morbidly Obese Patient -- Effects of MGB on Obesity-Related Co-Morbidities—Lipids, Hypertension, Non-alcoholic Fatty Liver, etc -- Effects of MGB on Type 2 Diabetes in Morbid Obesity. Comparison with the Other Operations -- Effects of MGB on Type 2 Diabetes in Lower BMI Patients -- Effect of MGB on the Obese Type 1 Diabetic -- The Question of Gastro-esophageal Reflux -- Treatment of Marginal Ulcer -- Quality of Life after MGB Compared to Other Operations -- Use of Single or Reduced Number of Ports -- Robotic MGB -- Absence of Gastric and Esophageal Carcinoma after MGB -- Revision of Lap-band to MGB -- Comparison of Results of MGB to Sleeve Gastrectomy and Roux-en-Y Gastric Bypass. Technique of Conversion of Failed Sleeve Gastrectomy to MGB -- Anti-reflux One-Anastomosis Gastric Bypass (OAGB) [Spanish BAGUA]: Step-by-step Technique, Rationale and Bowel Lengths -- Results of the OAGB: Effects on Co-Morbidities, Diabetes, Weight and Quality of Life, Nutritional Considerations, Pregnancy -- Results of the OAGB in Adolescents -- Physical Principles Applied to the OAGB -- Method of Revision of Sleeve Gastrectomy to OAGB -- The Ileal Food Diversion Operation: Technique, Rationale and Results -- Diverted MGB: A New Procedure -- Comparison of MGB with SADI-S: Revision of Sleeve Gastrectomy to MGB or Single Anastomosis Duodeno-Ileostomy (SADI) -- Single Anastomosis Gastro-ileal Bypass (SAGI) -- The MGB-OAGB International Club.
- Format
- e-Book
- Location
- Online
Dietary Patterns and Whole Plant Foods in Aging and Disease
https://libcat.nshealth.ca/en/permalink/provcat43277
Mark L. Dreher.
--Cham:
Humana Press
, c2018.
- Available Online
- View e-Book
- Location
- Online
This text provides a comprehensive review of the latest research on the effects of dietary patterns and whole plant foods on general health, aging, and cardiometabolic disease risk from major prospective cohort studies and randomized controlled trials (RCTs) and their meta-analyses. The book extensively assesses the effects of lifestyle, dietary patterns, and specific whole plant foods on the quality of aging; the impact of fiber-rich foods on colonic microbiotia and weight regulation, the effe…
- Available Online
- View e-Book
- Author
- Dreher, Mark L.
- Responsibility
- Mark L. Dreher
- Place of Publication
- Cham
- Publisher
- Humana Press
- Date of Publication
- c2018
- Physical Description
- 1 online resource (xxviii, 619 p.) : 225 illus., 204 illus. in color
- Series
- Nutrition and Health
- Series Title
- Nutrition and health (Totowa, N.J.)
- ISBN
- 9783319591803
- 9783319591797 (print ed.)
- 9783319591810 (print ed.)
- Subjects (MeSH)
- Aging - physiology
- Chronic Disease - prevention & control
- Feeding Behavior
- Healthy Aging - physiology
- Healthy Diet
- Plants, Edible - physiology
- Specialty
- Nutritional Sciences
- Abstract
- This text provides a comprehensive review of the latest research on the effects of dietary patterns and whole plant foods on general health, aging, and cardiometabolic disease risk from major prospective cohort studies and randomized controlled trials (RCTs) and their meta-analyses. The book extensively assesses the effects of lifestyle, dietary patterns, and specific whole plant foods on the quality of aging; the impact of fiber-rich foods on colonic microbiotia and weight regulation, the effects of which influence the quality of aging; the effects of fiber-rich diets on the aging gastrointestinal tract; and the role of dietary patterns and specific whole plant foods on coronary heart disease, hypertension, chronic kidney disease, stroke and type 2 diabetes. Figures are extensively used to highlight findings and tables summarizing food composition dietary patterns and whole plant foods. Tables summarizing meta-analyses and representative cohort studies and RCTs provide state-of-the-art coverage of the important effect of dietary patterns and whole plant foods on aging and cardiometabolic diseases. Dietary Patterns and Whole Plant Foods in Aging and Disease will serve as a very useful, state -of -the-art resource for dietitians, physicians, nurses, food industry scientists, researchers, naturopathic doctors, educators and their students interested in the role of dietary patterns and specific whole plant foods on aging and disease.
- Contents
- Part I. Overview of Aging and Disease -- 1. Major Lifestyles and Phenotypes in Aging and Disease -- 2. Dietary Patterns in Aging and Disease -- 3. Whole Plant Foods in Aging and Disease -- Part II. Gastrointestinal Tract -- 4. Fiber-Rich Dietary Patterns and Colonic Microbiota in Aging and Disease -- 5. Fiber-Rich Dietary Patterns and Foods in Laxation and Constipation -- 6. Dietary Patterns, Foods and Fiber in Irritable Bowel Syndrome and Diverticular Disease -- Part III. Weight Management and Related Diseases -- 7 Dietary Patterns and Fiber in Body Weight and Composition Regulation -- 8. Whole Plant Foods in Body Weight and Composition Regulation -- 9. Dietary Patterns and Whole Plant Foods in Type 2 Diabetes Prevention and Management -- 10. Dietary Patterns, Foods, Nutrients and Phytochemicals in Non-Alcoholic Fatty Liver Disease -- Part IV. Cardiovascular and Cerebrovascular Diseases, and Age-Related Cognitive Function -- 11. Dietary Patterns and Coronary Heart Disease -- 12. Whole Plant Foods and Coronary Heart Disease -- 13. Dietary Patterns and Hypertension -- 14. Whole Plant Foods and Hypertension -- 15. Dietary Patterns, Foods and Beverages in Chronic Kidney Disease -- 16. Dietary Patterns and Stroke Risk -- 17. Whole Plant Foods and Stroke Risk -- 18. Dietary Patterns, Foods and Beverages in Age-Related Cognitive Performance and Dementia -- Part V. Cancer Prevention and Survival -- 19. Dietary Patterns, Whole Plant Foods, Nutrients and Phytochemicals in Colorectal Cancer Prevention and Management -- 20. Dietary Patterns, Whole Plant Foods, Nutrients and Phytochemicals in Breast Cancer Prevention and Management.
- Format
- e-Book
- Location
- Online
Liver Disorders : A Point of Care Clinical Guide
https://libcat.nshealth.ca/en/permalink/provcat41300
Kia Saeian, Reza Shaker, editors.
--Cham:
Springer
, 2017.
- Available Online
- View e-Book
- Location
- Online
This book is a comprehensive and easy-to-access guide not only in the diagnosis of the various types of liver disease but in the management of specific disorders, including the particular nuances of the care of the patient with liver disease. It provides a resource to the practitioner caring for patients with liver disease for addressing everyday questions posed by patients and their families, as well as referring physicians, in a manner that can easily be conveyed. The spectrum covered includ…
- Available Online
- View e-Book
- Other Authors
- Saeian, Kia
- Shaker, Reza
- Responsibility
- Kia Saeian, Reza Shaker, editors
- Place of Publication
- Cham
- Publisher
- Springer
- Date of Publication
- 2017
- Physical Description
- 1 online resource (xiv, 636 pages) : 58 illus., 40 illus. in color
- ISBN
- 9783319301037
- 9783319301013 (print ed.)
- Subjects (MeSH)
- Liver Diseases
- Abstract
- This book is a comprehensive and easy-to-access guide not only in the diagnosis of the various types of liver disease but in the management of specific disorders, including the particular nuances of the care of the patient with liver disease. It provides a resource to the practitioner caring for patients with liver disease for addressing everyday questions posed by patients and their families, as well as referring physicians, in a manner that can easily be conveyed. The spectrum covered includes appropriate testing and disease monitoring of patients, use of medications, supplements, alternative therapies and alcohol, operative risk assessment, implementation of health maintenance for patients with chronic liver disease and cirrhosis, identification and management of particular complications of cirrhosis, and appropriate referral for liver transplantation, as well as management of special populations. Written by experts in the field, Liver Disorders: A Point of Care Clinical Guide is a valuable resource for clinicians who treat patients with a variety of liver disorders.
- Contents
- 1. What Do Abnormal Liver Tests Mean? -- 2. General Care of the Liver Patient -- 3. Do I - Need a Liver Biopsy? -- Part I: What to Do with Tumors in the Liver? -- 4. Incidental Hepatic Lesions -- 5. Benign Hepatic Lesions -- 6. Malignant Liver Lesions -- 7. Health Maintenance in Liver Disease and Cirrhosis -- 8. Preoperative and Postoperative Care of the Liver Patient -- Part II: Distinct Liver Disorders -- 9. Viral Hepatitis: Hepatitis A & E -- 10. Viral Hepatitis: Hepatitis B (& D) -- 11. Viral Hepatitis: Hepatitis C -- 12. Viral Hepatitis: Other Viral Hepatides -- 13. Alcoholic Liver Disease -- 14. Non-alcoholic Fatty Liver Disease -- 15. Autoimmune Liver Diseases: Autoimmune Hepatitis -- 16. Autoimmune Liver Diseases: Primary Biliary Cirrhosis -- 17. Autoimmune Liver Diseases: Primary Sclerosing Cholangitis -- 18. Autoimmune Liver Diseases: Overlap Syndromes -- 19. Metabolic and Genetic Liver Diseases: Alpha-1 Anti-Trypsin Deficiency -- 20. Metabolic and Genetic Liver Diseases: Hemochromatosis -- 21. Metabolic and Genetic Liver Diseases: Wilson's Disease -- 22. Metabolic and Genetic Liver Diseases: Glycogen Storage Diseases -- 23. Metabolic and Genetic Liver Diseases: Urea Cycle Defects -- 24. Metabolic and Genetic Liver Diseases: Porphyrias -- 25. Drug-Induced Liver Injury -- 26. Miscellaneous Disorders: Pregnancy Associated Liver Disorders, Vascular Disorders, Granulomatous Disease, and Amyloidosis -- Part III: Care of the Cirrhotic Patient -- 27. Portal Hypertension -- 28. Endoscopic Management of Portal Hypertension -- 29. Portosystemic Encephalopathy -- 30. Ascites -- 31. Spontaneous Bacterial Peritonitis (SBP) -- 32. Hepatorenal Syndrome -- 33. Hepatopulmonary Syndrome -- 34. Endoscopy and the Liver Patient -- 35. Liver Resection -- 36. Liver Transplantation: An Overview. .
- Format
- e-Book
- Location
- Online
Liver Disease in Clinical Practice
https://libcat.nshealth.ca/en/permalink/provcat41456
Tim Cross, editor.
--Cham:
Springer
, 2017.
- Available Online
- View e-Book
- Location
- Online
This pocket guide covers the common manifestations of liver disease, how to treat them and when to refer patients on to specialist centers. The book outlines the common clinical liver diseases such as fatty liver disease and hepatitis, among others, and their current up to date management. Written by experts in the field and containing figures and tables, as well as case histories and questions, this is an enjoyable and reader-friendly book for the busy physician. With its authoritative, didact…
- Available Online
- View e-Book
- Other Authors
- Cross, Tim
- Responsibility
- Tim Cross, editor
- Place of Publication
- Cham
- Publisher
- Springer
- Date of Publication
- 2017
- Physical Description
- 1 online resource (xv, 379 pages) : 22 illus., 11 illus. in color
- Series Title
- In clinical practice
- ISBN
- 9783319431260
- 9783319431253 (print ed.)
- ISSN
- 2199-6652
- Subjects (MeSH)
- Liver Diseases
- Abstract
- This pocket guide covers the common manifestations of liver disease, how to treat them and when to refer patients on to specialist centers. The book outlines the common clinical liver diseases such as fatty liver disease and hepatitis, among others, and their current up to date management. Written by experts in the field and containing figures and tables, as well as case histories and questions, this is an enjoyable and reader-friendly book for the busy physician. With its authoritative, didactic style and short chapters, it covers the common presentations and complications of liver disease, and how to deal with them. Given the increasing prevalence of liver disease in the UK and throughout Western Europe, this is an ideal reference book for primary care physicians, doctors in specialist training, clinical nurse specialists and for gastroenterologists, who see patients with liver disease in their working lives.
- Contents
- Part I. Clinical manifestations and approach to liver disease -- Assessment of liver function -- Liver Decompensation and Acute on Chronic Liver Failure -- Portal hypertension -- Hepatic encephalopathy -- Nutritional management of end-stage liver disease -- Part LL. Liver diseases of lifestyle, genes and metabolism -- Alcoholic liver disease -- Non-alcoholic fatty liver disease -- Genetic haemochromatosis -- The Orphan Liver Diseases -- Part III. Viral liver disease -- Chronic hepatitis B -- Chronic hepatitis C -- Part IV. Immune mediated liver disease -- Autoimmune hepatitis and cross-over syndromes -- Primary biliary cholangitis -- Primary sclerosing cholangitis -- Section V. Areas of special consideration -- Pregnancy and liver disease -- Hepatocellular carcinoma -- Liver transplantation -- The hepatological curiosities -- End of life care for patients with liver disease.
- Format
- e-Book
- Location
- Online
