Allergies and Adolescents : Transitioning Towards Independent Living
https://libcat.nshealth.ca/en/permalink/provcat42970
edited by David R. Stukus.
--Cham:
Springer
, c2018.
- Available Online
- View e-Book
- Location
- Online
This unique book is intended to assist readers in understanding various allergic diseases as they pertain to the adolescent, with a strong focus on encouraging their transition into self-management. Allergies and Adolescents thoroughly addresses both the cognitive and social development of adolescents and provides effective strategies for involving them in their own self-management. Different types of nonadherence are covered in detail, and specific conditions such as allergic rhinitis, asthma,…
- Available Online
- View e-Book
- Other Authors
- Stukus, David R.
- Responsibility
- edited by David R. Stukus
- Place of Publication
- Cham
- Publisher
- Springer
- Date of Publication
- c2018
- Physical Description
- 1 online resource (xiv, 246 p.) : 19 illus. in color
- ISBN
- 9783319774855
- 9783319774848 (print ed.)
- 9783319774862 (print ed.)
- Subjects (MeSH)
- Allergens
- Adolescent
- Specialty
- Adolescent Health
- Allergy and Immunology
- Abstract
- This unique book is intended to assist readers in understanding various allergic diseases as they pertain to the adolescent, with a strong focus on encouraging their transition into self-management. Allergies and Adolescents thoroughly addresses both the cognitive and social development of adolescents and provides effective strategies for involving them in their own self-management. Different types of nonadherence are covered in detail, and specific conditions such as allergic rhinitis, asthma, food allergy, and eczema each have a chapter devoted to a comprehensive discussion of basic concepts surrounding diagnosis and management. These chapters are then followed by a separate chapter providing details as to how that condition can specifically impact adolescents. Chapters containing practical tips that can be immediately implemented by adolescents and their families as well as clinicians conclude the book. Written by experts in their respective fields, Allergies and Adolescents is a comprehensive resource for multiple audiences, including the allergist, pediatrician, and any other healthcare provider working with adolescents, guiding them towards self-management, and preparing them for independent living.
- Contents
- 1. The Allergy Epidemic -- 2. Adolescent Brain Development and Implications for Adolescents with Allergies -- 3. How Can We Best Communicate with Adolescents? -- 4. The Many Faces of Nonadherence in Adolescents -- 5. Allergic Rhinitis -- 6. Allergic Rhinitis Pertaining to Adolescents -- 7. Asthma: A Heterogeneous and Challenging Chronic Condition -- 8. Managing Adolescent Asthma: More than Just Medications -- 9. Food Allergies: An Overview -- 10. Food Allergies and the Teenager -- 11. Atopic Dermatitis: Overview -- 12. Atopic Dermatitis Pertaining to Adolescents -- 13. her Allergic Conditions: Venom Hypersensitivity, Drug Allergy, Chronic Urticaria/Angioedema, Primary Immune Deficiency -- 14. at Now? Practical Steps for Adolescents with Allergies and Asthma to Manage Their Healthcare Independently -- 15. Practical Approach for Clinicians to Prepare -- Adolescents for Independent Living.
- Format
- e-Book
- Location
- Online
Allergy and Asthma : The Basics to Best Practices
https://libcat.nshealth.ca/en/permalink/provcat44500
Massoud Mahmoudi, editor-in-chief.
--Cham:
Springer
, c2019.
- Available Online
- View e-Book
- Location
- Online
Allergy and Asthma: The Basics to Best Practices is intended to serve as a single comprehensive reference covering all needed knowledge of allergic diseases. Allergy is a unique and distinctive area of medicine wherein learning the fundamentals requires gathering information from various different disciplines. Allergic diseases affect various organ systems and the practice of a wide range of physicians from otolaryngologists, and pulmonologists, to gastroenterologists, dermatologists, and ophth…
- Available Online
- View e-Book
- Other Authors
- Mahmoudi, Massoud
- Responsibility
- Massoud Mahmoudi, editor-in-chief
- Place of Publication
- Cham
- Publisher
- Springer
- Date of Publication
- c2019
- Physical Description
- 1 online resource (xxiv, 1101 p.) : 126 illus., 95 illus. in color
- ISBN
- 9783030051471
- 9783030051464 (Print ed.)
- Subjects (MeSH)
- Anti-Allergic Agents - therapeutic use
- Asthma - diagnosis
- Asthma - therapy
- Hypersensitivity - diagnosis
- Hypersensitivity - therapy
- Specialty
- Allergy and Immunology
- Abstract
- Allergy and Asthma: The Basics to Best Practices is intended to serve as a single comprehensive reference covering all needed knowledge of allergic diseases. Allergy is a unique and distinctive area of medicine wherein learning the fundamentals requires gathering information from various different disciplines. Allergic diseases affect various organ systems and the practice of a wide range of physicians from otolaryngologists, and pulmonologists, to gastroenterologists, dermatologists, and ophthalmologists. Clinicians and trainees alike will benefit from a resource that introduces the basic concepts, as well as providing comprehensive, consistently up-to-date instruction on intermediate and advanced conditions, research, and treatment strategies. The book is divided into nine sections and is written by some of the foremost experts in the field. Allergy and Asthma opens with an introduction which covers the epidemiology of allergic diseases, fundamentals of allergy and immunology, and a thorough grounding of different types of allergens. Early sections address allergic upper airway diseases, allergic skin diseases, and asthma in detail, using a structured, consistent format from chapter to chapter to provide continuity and ease of reference. Later sections thoroughly cover various food allergies, insect allergies, drug allergy, anaphylaxis, and utilize ample tables and illustrations to provide additional learning tools for the reader. This major reference not only provides basic knowledge on diagnosing and treating allergies, but moves beyond these basics to emphasize using a systematic approach to working up and treating a patient. A variety of techniques used in diagnosing asthma and allergy will be examined, of which include prick skin tests, in-vitro testing, patch testing and non-conventional allergy tests. Concluding this book are sections dedicated to management, therapeutic strategies of allergy and asthma, with a look to future research directions for this unique field. Physicians and residents in allergy and immunology, pulmonology, otolaryngology, gastroenterology, dermatology, ophthalmology and other specialties will find the work of value in enhancing their practice and studies. Researchers in a range of areas especially immunology and food science will also find this text to be a compelling and reliable resource.
- Contents
- Part I. Introduction -- 1. Overview of Immunology and Allergy -- 2. Epidemiology of Allergic Diseases -- 3. Definition of Allergens: Inhalants, Food, and Insects Allergens -- Part II. Allergic Upper Airway Disease -- 4. Allergic Ocular Diseases -- 5. Allergic Rhinitis -- 6. Chronic Rhinosinusitis and Nasal -- Part III. Allergic Skin Diseases and Urticaria -- 7. Atopic Dermatitis -- 8. Acute and Chronic Urticaria -- 9. Hereditary Angioedema -- 10. Allergic Contact Dermatitis -- Part IV. Asthma -- 11. Asthma Phenotypes and Biomarkers -- 12. Adult Asthma -- 1.3 Childhood Asthma -- 14. Aspirin or Nonsteroidal Drug-Exacerbated Respiratory Disease (AERD or NERD) -- 15. Occupational Asthma -- 16. Differential Diagnosis of Asthma -- 17. Asthma in Athletes -- 18. Asthma in Pregnancy -- 19. Cough and Allergic Diseases -- 20. Allergic Bronchopulmonary Aspergillosis -- Part V Drug and Latex Allergy -- 21. Drug Allergy and Adverse Drug Reactions -- 22. Penicillin Allergy and Other Antibiotics -- 23. Chemotherapy and Biologic Drug Allergy -- 24. Latex Allergy -- Part VI Food Allergy and Eosinophilic Esophagitis -- 25. IgE Food Allergy -- 26. Non-IgE Food Immunological Diseases -- 27. Eosinophilic Esophagitis -- Part VII. Insect Allergy and Anaphylaxis -- 28. Anaphylaxis and Systemic Allergic Reactions - 29. Mast Cell Disorders and Anaphylaxis -- 30. Insect Allergy: A Review of Diagnosis and Treatment -- 31. Allergy from Ants and Biting Insects -- Part VIII. Allergy and Asthma Diagnosis -- 32. Allergy Skin Testing -- 33. In Vitro Allergy Testing -- 34. Pulmonary Function, Biomarkers, and Bronchoprovocation -- Part IX. Treatment of Asthma and Allergy -- 35. Primary and Secondary Environmental Control Measures for Allergic Diseases -- 36. Pharmacologic Therapy for Rhinitis and Allergic Eye Disease -- 37. Bronchodilator Therapy for Asthma -- 38. Inhaled Corticosteroid Therapy for Asthma -- 39. Subcutaneous Immunotherapy for Allergic Rhinitis and Asthma -- 40. Sublingual Immunotherapy for Allergic Rhinitis and Asthma -- 41. Biologic and Emerging Therapies for Allergic Disease.
- Format
- e-Book
- Location
- Online
Allergy and Immunotoxicology in Occupational Health
https://libcat.nshealth.ca/en/permalink/provcat41941
Takemi Otsuki, Claudia Petrarca, Mario Di Gioacchino, editors.
--Singapore:
Springer
, 2017.
- Available Online
- View e-Book
- Location
- Online
This book offers a collection of the latest clinical and research findings related to allergies, one of the most frequently treated conditions in occupational medicine. The chapters not only cover asthma but also elaborate on contact dermatitis, rhinitis, and other allergic conditions, providing readers with a comprehensive overview of the substances disrupting autoimmunity and their effects on the human body. Allergy and Immunotoxicology in Occupational Health is a valuable resource for profes…
- Available Online
- View e-Book
- Other Authors
- Otsuki, Takemi
- Petrarca, Claudia
- Di Gioacchino, Mario
- Other Authors
- International Congress of Occupational Health. Allergy and Immunotoxicology Scientific Committee
- Responsibility
- Takemi Otsuki, Claudia Petrarca, Mario Di Gioacchino, editors
- Place of Publication
- Singapore
- Publisher
- Springer
- Date of Publication
- 2017
- Physical Description
- 1 online resource (x, 152 pages) : 14 illus., 13 illus. in color
- ISBN
- 9789811003516
- 9789811003493 (print ed.)
- ISSN
- 2364-8333
- Subjects (MeSH)
- Environmental Pollutants - toxicity
- Multiple Chemical Sensitivity - immunology
- Occupational Diseases - immunology
- Occupational Health
- Abstract
- This book offers a collection of the latest clinical and research findings related to allergies, one of the most frequently treated conditions in occupational medicine. The chapters not only cover asthma but also elaborate on contact dermatitis, rhinitis, and other allergic conditions, providing readers with a comprehensive overview of the substances disrupting autoimmunity and their effects on the human body. Allergy and Immunotoxicology in Occupational Health is a valuable resource for professionals and researchers in the occupational health sector, who will discover novel insights into immune effects, providing a foundation for future considerations of the health impairments caused by environmental and occupational exposure to these substances.
- Contents
- 1. Suppressive Effects of Asbestos Exposure on the Human Immune Surveillance System -- 2. Silica-Induced Immunotoxicity: Chronic and Aberrant Activation of Immune Cells -- 3. Engineered Nanomaterials and Occupational Allergy -- 4. Allergens in Occupational Allergy: Prevention and Management – Focus on Asthma -- 5. Particulate-Driven Type-2 Immunity and Allergic Responses -- 6. Traditional and Emerging Occupational Asthma in Japan -- 7. Skin Sensitization Model Based on Only Animal Data by Qualitative Structure-Toxicity Relationships (QSTR) Approach -- 8. Non-industrial Indoor Environments and Work-Related Asthma -- 9. Combined Effect on Immune and Nervous System of Aluminum Nanoparticles -- 10. Non Pulmonary Effects of Isocyanates -- 11. Skin Exposure to Nanoparticles and Possible Sensitization Risk.
- Format
- e-Book
- Location
- Online
Allergy frontiers. Vol. 1, Epigenetics, allergens and risk factors
https://libcat.nshealth.ca/en/permalink/provcat29105
- Available Online
- View e-Book
- Other Authors
- Pawankar, Ruby
- Holgate, Stephen T
- Rosenwasser, Lanny J
- Place of Publication
- Tokyo
- Publisher
- Springer Japan
- Date of Publication
- c2009
- Series Title
- Allergy Frontiers
- ISBN
- 9784431728023
- Subjects (MeSH)
- Hypersensitivity - epidemiology
- Hypersensitivity - genetics
- Allergens
- Subjects (LCSH)
- Allergy
- Format
- e-Book
- Location
- Online
Contact and occupational dermatology
https://libcat.nshealth.ca/en/permalink/provcat21578
Marks, James G.
(3rd ed.)
--Saint Louis, MO:
Mosby
, 2002.
- Call Number
- WR 175 M346c 2002
- Location
- Dickson Building
- Call Number
- WR 175 M346c 2002
- Author
- Marks, James G
- Other Authors
- Elsner, Peter
- DeLeo, Vincent A
- Edition
- 3rd ed.
- Place of Publication
- Saint Louis, MO
- Publisher
- Mosby
- Date of Publication
- 2002
- Physical Description
- 431 p.
- ISBN
- 0323014739
- Subjects (MeSH)
- Dermatitis, Contact
- Dermatitis, Occupational
- Allergens - toxicity
- Format
- Book
- Location
- Dickson Building
- Loan Period
- 3 weeks
Contact Dermatitis
https://libcat.nshealth.ca/en/permalink/provcat44581
edited by Jeanne Duus Johansen, Vera Mahler, Jean-Pierre Lepoittevin, Peter J. Frosch.
(Sixth edition)
--Cham:
Springer
, c2020.
- Available Online
- View e-Book
- Location
- Online
The sixth edition of Contact Dermatitis covers in detail every conceivable aspect of irritant and allergic contact dermatitis and its modern-day management. The 1st edition of this book was published in 1992 and has served as the main reference book of contact dermatitis. In this new edition special emphasis is given to immunological mechanisms, molecular aspects of sensitizers, atypical clinical forms, patch test methodology, reactions to medicaments, and occupational and environmental factors…
- Available Online
- View e-Book
- Responsibility
- edited by Jeanne Duus Johansen, Vera Mahler, Jean-Pierre Lepoittevin, Peter J. Frosch
- Edition
- Sixth edition
- Place of Publication
- Cham
- Publisher
- Springer
- Date of Publication
- c2020
- Physical Description
- 1 online resource
- Series Title
- Springer reference
- ISBN
- 9783319724515
- Subjects (MeSH)
- Dermatitis, Contact
- Specialty
- Dermatology
- Environmental Health
- Notes
- "Living reference work."
- Abstract
- The sixth edition of Contact Dermatitis covers in detail every conceivable aspect of irritant and allergic contact dermatitis and its modern-day management. The 1st edition of this book was published in 1992 and has served as the main reference book of contact dermatitis. In this new edition special emphasis is given to immunological mechanisms, molecular aspects of sensitizers, atypical clinical forms, patch test methodology, reactions to medicaments, and occupational and environmental factors. In order to optimize the diagnostic approach, a wide range of information is provided, including a dictionary of contact allergens and detailed information on exposure assessment. Retained chapters from the previous edition have been thoroughly revised to reflect the latest knowledge. Furthermore, completely new chapters have been added on a variety of topics, including contact allergy to medical implants, relevant allergens in gloves and immediate reactions to occupational materials. The editors and authors are all leading practitioners in the field. The comprehensive but approachable text is supplemented by a large number of full colour illustrations and tables. Core messages highlight the most important information and will help the reader to gain a better understanding of the subject and greater competence in everyday practice.
- Contents
- Allergic Contact Dermatitis in Humans: Experimental and Quantitative Aspects -- Atopy Patch Testing with Aeroallergens and Food Proteins -- Clinical Aspects of Irritant Contact Dermatitis -- Comments on Various Baseline Series -- Contact Allergy in Children -- Contact Dermatitis Research Groups -- Databases and Networks: The Benefit for Research and Quality Assurance in Patch Testing -- Dental Materials and Implants -- Dictionary of Contact Allergens: Chemical Structures, Sources, and References -- Epidemiology -- Gloves -- Hair Dyes -- Histopathological and Immunohistopathological Features of Irritant and Allergic Contact Dermatitis -- Identification of Allergens in Complex Mixtures and Products -- Immediate-Type Hypersensitivity by Occupational Materials -- Legislation -- Mechanisms of Irritant and Allergic Contact Dermatitis -- Metalworking Fluids -- Noneczematous Contact Reactions -- Noninvasive Techniques for Quantification of Contact Dermatitis -- Occupational Contact Dermatitis: Hairdressers -- Occupational Contact Dermatitis: Health Personnel -- Patch Testing with the Patients’ Own Products -- Photopatch Testing -- Plastic Materials and Glues -- Predictive Tests for Irritants and Allergens: Human, Animal, and In Vitro Tests -- Preservatives -- Prevention of Allergic Contact Dermatitis: Safe Exposure Levels of Sensitizers -- Protein Contact Dermatitis -- Respiratory Symptoms from Fragrances and the Link with Dermatitis -- Shoes -- Systemic Contact Dermatitis -- Textiles -- The Chinese Baseline Series -- The European Baseline Series -- The North American Baseline Series.
- Format
- e-Book
- Location
- Online
Dictionary of Contact Allergens
https://libcat.nshealth.ca/en/permalink/provcat29064
by Jean-Pierre Lepoittevin, Christophe J. Coz.
--Berlin, Heidelberg:
Springer-Verlag
, c2007.
- Available Online
- View e-Book
- Location
- Online
- Available Online
- View e-Book
- Author
- Lepoittevin, Jean-Pierre
- Other Authors
- Coz, Christophe J
- Responsibility
- by Jean-Pierre Lepoittevin, Christophe J. Coz
- Place of Publication
- Berlin, Heidelberg
- Publisher
- Springer-Verlag
- Date of Publication
- c2007
- ISBN
- 9783540741657
- Subjects (MeSH)
- Allergens - chemistry - Dictionary
- Dermatitis, Contact - etiology
- Subjects (LCSH)
- Allergy
- Dermatology
- Format
- e-Book
- Location
- Online
Encyclopedia of medical immunology : allergic diseases
https://libcat.nshealth.ca/en/permalink/provcat33460
Ian R. Mackay, Noel R. Rose, editors-in-chief ; Dennis K. Ledford, Richard F. Lockey, editors.
--Berlin:
Springer
, c2014.
- Available Online
- View e-Book
- Location
- Online
- Available Online
- View e-Book
- Other Authors
- Mackay, Ian M
- Rose, Noel R
- Responsibility
- Ian R. Mackay, Noel R. Rose, editors-in-chief ; Dennis K. Ledford, Richard F. Lockey, editors
- Alternate Title
- Encyclopedia of medical immunology. Vol. 3, Allergic diseases
- Allergic diseases
- Place of Publication
- Berlin
- Publisher
- Springer
- Date of Publication
- c2014
- Physical Description
- 1 online resource (xxxvii, 676 pages)
- ISBN
- 9781461491941 (electronic bk.)
- 9781461491934
- Subjects (LCSH)
- Allergy - Encyclopedias
- Contents
- A: -- Activating and Inhibitory Receptors on Mast Cells -- Allergen Avoidance: Avoidance Strategies for Skin Allergies -- Allergen Avoidance: Cockroach and Rodent Avoidance -- Allergen Avoidance: Dietary Management of Food Allergy -- Allergen Avoidance: Dust Mite Avoidance -- Allergen Avoidance: Fungi and Mold Avoidance -- Allergen Avoidance: Furry Animal Avoidance -- Allergen Avoidance: Pollen Avoidance - Tree, Grass, and Weed -- Allergen Immunotherapy, Overview -- Allergens in Gloves -- Allergic Bronchopulmonary Aspergillosis -- Allergic Contact Dermatitis -- Allergic Contact Dermatitis from Exotic Woods -- Allergic Proctocolitis and Food Protein-Induced Enterocolitis Syndrome (FPIES) -- Aluminum Allergy -- Analytes and Biomarkers: Environmental Allergen Assessment -- Analytes and Biomarkers: IgE -- Analytes and Biomarkers: Nitric Oxide (NO) and Asthma -- Analytes and Biomarkers: Precipitin Antibodies -- Anaphylaxis, Background -- Anaphylaxis, Clinical Manifestations and Diagnosis -- Articaine Allergic Reaction -- Aspirin-Exacerbated Respiratory Disease -- Assay Performance Parameters -- Asthma Variants: Allergic Asthma -- Asthma Variants: Cough-Variant Asthma -- Atopic Dermatitis -- Autoimmune Lung Disease -- B: -- Basophils -- Biphasic, Protracted, and Late-Phase Reactions in Anaphylaxis -- Biting Insects (Systemic and Local Reactions) -- Bronchial Challenges -- Bronchiectasis -- C: -- Cobalt Contact Dermatitis -- Contact Allergy to Black Henna Tattoos -- Contact Allergy to Epoxy Resins -- Contact Allergy to Hair Dyes -- Contact Allergy to Shoe Components -- Contact Dermatitis Due to New Metals -- Contact Dermatitis Due to Plants -- Contact Dermatitis Due to Thiourea Derivatives -- Contact Dermatitis Due to Topical Drugs -- Contact Dermatitis Due to Topical Traditional Chinese Medicine -- Contact Dermatitis in Children -- Contact Sensitization to Modern Wound Dressing -- Contact Urticaria and Protein Contact Dermatitis (to Asparagus, Cow's Hair, Seafood, Etc.) -- Cotinine -- Cow's Milk Allergy -- Cutaneous Drug Reactions -- D: -- Delayed Allergic Hypersensitivity to Corticosteroids -- Delayed Anaphylaxis to Mammalian Meat (Alpha-Gal) -- Dendritic Cells -- Dermatitis from 2-N-Octyl-4-Isothiazolin-3-One, Allergic Contact -- Diagnostic Assay Components -- Diagnostic Components: Allergen for In Vivo (Skin Testing, Immunotherapy) and In Vitro (Serology) IgE Antibody Testing -- Diagnostic Components: T Helper Cell Cytokines (IL-4, IL-5, IL-9, IL-10, IL-13, IL-17) -- Diagnostic Food Challenges -- Diagnostic Terms: Atopy -- Diagnostic Terms: Point-of-Care Testing -- 3-Dimethylaminopropylamine (DMAPA), Allergic Contact Dermatitis to -- Diseases in DDx of Asthma: Alpha 1 AT Deficiency -- Diseases in DDx of Asthma: Bronchopulmonary Dysplasia -- Diseases in DDx of Asthma: COPD -- Diseases in DDx of Asthma: Croup -- Diseases in DDx of Asthma: Differential Diagnosis of Asthma -- Diseases in DDx of Asthma: Vocal Cord Dysfunction -- Diseases in Differential Diagnosis of Asthma: Hypersensitivity Pneumonitis -- E: -- Egg Allergy -- Emergent Allergies in Cosmetics -- Eosinophil Activation -- Eosinophil Granule Proteins -- Eosinophil Historical Background -- Eosinophil Progenitors, Growth, and Differentiation and Death -- Eosinophil Receptor Expression -- Eosinophil Recruitment -- Eosinophil, Definition and Morphology -- Eosinophilic Esophagitis -- Eosinophilic Gastrointestinal Disorders -- Eosinophils in Disease -- Epidemic Contact Dermatitis due to Dimethyl Fumarate -- Epidemiology of Food Allergy -- Etiology of Anaphylaxis -- Exercise Challenge -- Exhaled Nitric Oxide -- Eyes and Eyelid, Contact Allergic Reaction On -- F: -- Fatal Allergic Reactions to Foods -- Fingernails from Sensitization to Acrylic, Loss of -- Food Allergens -- Food Allergies, Diagnostic Testing -- Food Allergy and its Future Treatment -- Food Allergy, Overview -- Food Desensitization -- Fragrance Contact Allergy -- Fragrancy, Allergic Contact Dermatitis -- G: -- Genetic Regulation of IgE -- Gluten Intolerance and Skin Diseases -- Gold Contact Dermatitis -- H: -- Hairdressers' Occupational Skin Disease -- Herbal Remedies -- Homeopathy in the Treatment of Allergic Diseases -- Honeybee Allergy -- Hypereosinophilic Syndromes -- Hyper-IgE Syndrome -- I: -- Idiopathic Acute Eosinophilic Pneumonia -- Idiopathic Chronic Eosinophilic Pneumonia -- Idiopathic Pulmonary Fibrosis -- IgE Isotype Switching -- IgE Receptor -- IgE Testing -- IgE-Secreting Plasma Cells -- Immunomodulator Therapy of Asthma -- Immunomodulator Therapy of Chronic Urticaria -- Immunomodulator Therapy of Hypereosinophilic Syndrome -- Immunomodulator Therapy of Mastocytosis -- Immunotherapy for Allergic Rhinitis -- Immunotherapy for Asthma -- Immunotherapy for Hymenoptera Allergy -- Immunotherapy with Recombinant and DNA-Conjugated Allergens -- Immunotherapy, Mechanisms -- Imported Fire Ant Allergy -- Induction of IgE Synthesis: Cellular Interactions and Molecular Events -- Insect Allergy in Children -- Intranasal Anticholinergics -- Intranasal Antihistamines -- Intranasal Corticosteroids -- Intranasal Decongestants -- Intranasal Mast Cell Stabilizers -- Intraocular Vasoconstrictors -- L: -- Laboratory and Assay Evaluation -- Leukotriene Modifiers -- M: -- mAbs (Omalizumab) -- Management of Anaphylaxis -- Mannitol Challenge -- Mast Cell Mediators -- Mast Cell Mediators Associated with Anaphylaxis -- Mast Cells -- Mast Cells, Growth and Development -- Mastocytosis -- Methacholine Challenge -- Methods (In Vitro and In Vivo): Multiplex Immunoassay Systems -- Methods (In Vitro and In Vivo): Nephelometry and Turbidimetry -- Methods (In Vivo) Provocation Tests (Nasal Challenge, Bronchial Challenge, Food Challenge) -- Methods (In Vivo): Methacholine Challenge -- Methods (In Vivo): Skin Test (Intradermal, Puncture) -- Methyldibromo Glutaronitrile, Contact Allergy to -- Methylisothiazolinone Allergy -- Microscopic Polyangiitis -- Morphology and Histologic Identification of Mast Cells -- N: -- Nail Contact Dermatitis, Including Allergic Contact Dermatitis Due to Nail Cosmetics -- Netherton's Syndrome -- Nickel Allergic Contact Dermatitis -- Nickel Contact Dermatitis -- Nitroglycerin Dermatitis -- Nonasthmatic Eosinophilic Bronchitis -- Nutrition in Food Allergy -- O: -- Occupational Contact Dermatitis Due to Acrylates and Methacrylates -- Ocular Antihistamines -- Ocular Corticosteroids -- Oral Allergy Syndrome -- Oral Antihistamines -- Oral Corticosteroids -- Oral Decongestants -- Oral Mast Cell Stabilizers -- P: -- Pathophysiology of Anaphylaxis -- Peanut Allergy -- Peanut Allergy, Diagnosis and Management -- Photoallergic Contact Dermatitis -- Photopatch Test Baseline Series -- Plants, Allergic Contact Dermatitis from -- Polidocanol: A Contact Allergen in Shampoo -- p-Phenylenediamine Occupational Contact Dermatitis -- Predictive Value Model for Laboratory Tests: Diagnostic Sensitivity, Diagnostic Specificity, Positive and Negative Predictive Value, Efficiency, Likelihood Ratio ([positive and negative]), Incidence and Prevalence -- Preservatives Contact Allergy -- Protein Contact Dermatitis -- Pulmonary Function Testing -- R: -- Role of IgE in Disease -- Role of Mast Cells in Diseases -- S: -- Safety of Immunotherapy -- Sensitization and Allergy to Natural Rubber Latex -- Single-Plex Immunoassays and Autoanalyzers -- Specific IgE -- Sublingual Immunotherapy -- T: -- Testing: DLCO -- Testing: High-Resolution Chest Computed Tomography Scan -- Testing: Sputum Eosinophil Count -- Textile Allergy -- Titanium Alloy, Dermatitis, Allergic Contact, Granulomatous -- Topical Antihistamines -- Topical Corticosteroids -- Topical Preparations: Calcineurin Inhibitors -- Tracheobronchomalacia and Hyperdynamic Airway Collapse -- U: -- Urticaria -- V: -- Venom Content -- Vespid Allergy: Yellow Jackets, Hornets and Wasps.
- Format
- e-Book
- Location
- Online
Environment and Skin
https://libcat.nshealth.ca/en/permalink/provcat43065
Jean Krutmann, Hans F. Merk, editors.
--Cham:
Springer
, c2018.
- Available Online
- View e-Book
- Location
- Online
This book is a rich source of information on skin disorders due to toxicants in the environment. State of the art knowledge is summarized concerning the molecular basis of skin damage caused by well-appreciated environmental noxae. The book also provides a uniquely comprehensive overview of the detrimental dermatological effects of exposure to air pollution and global climate change. A special focus is contact allergy, which, beyond representing a major problem in dermatotoxicology, serves as a…
- Available Online
- View e-Book
- Other Authors
- Krutmann, Jean
- Merk, Hans F.
- Responsibility
- Jean Krutmann, Hans F. Merk, editors
- Place of Publication
- Cham
- Publisher
- Springer
- Date of Publication
- c2018
- Physical Description
- 1 online resource (v, 130 p.) : 26 illus., 18 illus. in color
- ISBN
- 9783319431024
- 9783319431000 (print ed.)
- 9783319431017 (print ed.)
- 9783319827391 (print ed.)
- Subjects (MeSH)
- Allergens - adverse effects
- Dermatitis, Contact
- Environmental Exposure - adverse effects
- Skin Diseases
- Skin
- Specialty
- Dermatology
- Environmental Health
- Abstract
- This book is a rich source of information on skin disorders due to toxicants in the environment. State of the art knowledge is summarized concerning the molecular basis of skin damage caused by well-appreciated environmental noxae. The book also provides a uniquely comprehensive overview of the detrimental dermatological effects of exposure to air pollution and global climate change. A special focus is contact allergy, which, beyond representing a major problem in dermatotoxicology, serves as a prime example for the development of toxicological approaches to risk assessment. A further chapter is devoted to contact urticaria, a condition that can progress to life-threatening anaphylactic reactions. The novel information offered in this book will enable the reader to go beyond the traditional thinking of dermatotoxicology and achieve a modern appreciation of the highly complex interplay between skin and environment.
- Contents
- Part. I Concepts and Methods -- 1. Barrier Skin -- 2. Combined, Simultaneous Exposure to Radiation Within and Beyond the UV Spectrum: A Novel Approach to Better Understand Skin Damage by Natural Sunlight -- 3. The Impact of Climate Change on Skin and Skin-Related Disease -- 4. Modern Skin Toxicity Testing Strategies -- Part II. Environmental Threats to the Skin -- 5. Contact Allergy -- 6. Contact Urticaria and Contact Urticaria Syndrome -- 7. Risk Assessment for Contact Allergens -- 8. UV and Skin: Photocarcinogenesis -- 9. Ambient Particulate Matter and Skin -- 10. POPs and Skin.
- Format
- e-Book
- Location
- Online
Filaggrin : basic science, epidemiology, clinical aspects and management
https://libcat.nshealth.ca/en/permalink/provcat33854
Jacob P. Thyssen, Howard I. Maibach, editors.
--Heidelberg:
Springer
, c2014.
- Available Online
- View e-Book
- Location
- Online
Filaggrin proteins are expressed in several human tissues, including the skin, oral mucosa, conjunctivae, esophagus, cervix, and testes. While filaggrin guarantees both structural and functional normality of the human epidermis, its role in other tissues is largely unknown. Epidermal deficiency of filaggrin causes dry and scaly skin, but also strongly increases the risk of skin diseases, in particular ichthyosis vulgaris and atopic dermatitis. Importantly, the risk of related asthma, hay fever,…
- Available Online
- View e-Book
- Other Authors
- Thyssen, Jacob P.
- Maibach, Howard I.
- Responsibility
- Jacob P. Thyssen, Howard I. Maibach, editors
- Place of Publication
- Heidelberg
- Publisher
- Springer
- Date of Publication
- c2014
- Physical Description
- 1 online resource (xv, 373 pages)
- ISBN
- 9783642543791 (electronic bk.)
- 9783642543784
- Subjects (MeSH)
- Intermediate Filament Proteins
- Subjects (LCSH)
- Skin - Diseases - Genetic aspects
- Medical genetics
- Abstract
- Filaggrin proteins are expressed in several human tissues, including the skin, oral mucosa, conjunctivae, esophagus, cervix, and testes. While filaggrin guarantees both structural and functional normality of the human epidermis, its role in other tissues is largely unknown. Epidermal deficiency of filaggrin causes dry and scaly skin, but also strongly increases the risk of skin diseases, in particular ichthyosis vulgaris and atopic dermatitis. Importantly, the risk of related asthma, hay fever, and food allergy is also increased although filaggrin is not expressed in the airways and gastrointestinal tract. Common FLG mutations, leading to reduced filaggrin expression, have mainly been identified in Europeans and Asians, reaching a prevalence of 5-10%. Even in the absence of atopic dermatitis, the skin of individuals with FLG mutations differs fundamentally from normal skin, for example by generating more vitamin D and allowing chemicals and allergens to more widely penetrate across the stratum corneum. This textbook provides comprehensive and detailed coverage of the effects of filaggrin and filaggrin gene (FLG) mutations in health and disease (cutaneous and non-cutaneous) and also discusses the basic science, epidemiology, management, and future research areas.
- Contents
- Part I. Basic Science -- Function of Filaggrin and Its Metabolites -- Morphology of Filaggrin-Depleted Epidermis -- Stratum Corneum Lipids and Filaggrin -- Inflammatory-Driven Depletion of Filaggrin Proteins -- Immune Activity and Vitamin D -- Filaggrin-2 -- Part II. Identification and Study Methods -- Animal Models -- In Vitro Models of Filaggrin-Associated Diseases -- Mapping Posttranslational Regulation of Filaggrin Using Phosphoproteomics -- Noninvasive Detection of Filaggrin Molecules by Raman Spectroscopy -- Filaggrin Genotyping -- Part III. Epidemiology and Environmental Exposures -- Prevalence of Filaggrin Gene Mutations: An Evolutionary Perspective -- Filaggrin Gene Mutations in Asian Races -- Filaggrin Gene Loss-of-Function Mutations and Exposure to Endocrine Disrupting Environmental Chemicals -- Part IV. Filaggrin and Atopic Disease -- Filaggrin Mutations and the Atopic March -- Atopic Dermatitis -- Asthma -- Filaggrin Mutations, Skin Barrier Dysfunction, and Sensitization in Allergic Rhinitis -- Filaggrin and Non-cutaneous Disease: Food Allergy -- Filaggrin in Canine Skin -- Part V. Filaggrin and Cutaneous Disease -- Ichthyosis Vulgaris and Other Disorders of Cornification -- Xerosis Means "Dry Skin": Mechanisms, Skin Conditions, and Its Management -- Allergic Contact Dermatitis -- Irritant Contact Dermatitis -- Hand Eczema -- Filaggrin in Psoriasis -- Filaggrin and Skin Infections -- Atopic Dermatitis and Skin Cancer -- Filaggrin Gene Mutations: A Clinician's Perspective -- Part VI. Filaggrin and Non-cutaneous Disease -- Filaggrin, the Skin Barrier, and Diabetes -- The Eye and Filaggrin -- Filaggrin Dysfunction and Its Association with Inflammatory Conditions of the GI Tract -- Filaggrin, Human Papillomavirus, and the Cervix -- Antibodies Against Citrullinated Proteins and Filaggrin -- Filaggrin and the Oral Mucosa -- Part VII. Management -- Therapeutics and Other Interventions.
- Format
- e-Book
- Location
- Online
Food toxicants analysis : techniques, strategies and developments
https://libcat.nshealth.ca/en/permalink/provcat27209
edited by Yolanda Picó.
--Boston, MA:
Elsevier B. V
, 2007.
- Available Online
- View e-Book
- Location
- Online
- Available Online
- View e-Book
- Author
- Picó, Yolanda
- Responsibility
- edited by Yolanda Picó
- Place of Publication
- Boston, MA
- Publisher
- Elsevier B. V
- Date of Publication
- 2007
- ISBN
- 6610747253 (electronic bk.)
- Subjects (MeSH)
- Food Analysis
- Food Contamination
- Toxicity Tests
- Contents
- Cover -- Copyright Page -- Table of Contents -- Preface -- Contributor contact details -- Part 1: Regulations -- Chapter 1 The international regulation of chemical toxicants in food: Codex Alimentarius -- 1. General principles of Codex Alimentarius -- 2. Operation of Codex Alimentarius -- 3. Decision making and enforcement mechanisms in Codex Alimentarius -- 4. Codex standard for contaminants and toxins in foods Codex Stan 193-1995 (Rev.1-1997) -- References -- Chapter 2 Different legislations on toxicants in foodstuffs -- 1. Food toxicants and Food safety -- 2. European Union -- 3. USA -- 4. Mercosur legislation -- 5. Asia-Pacific Region -- 6. Concluding Remarks -- References -- Part 2. Risk and Quality Assurance -- Chapter 3 Risk assessment of food additives and contaminants -- 1. Risk assessment procedures -- 2. The case of Sunset Yellow -- 3. Future food risk assessment -- 4. References -- Chapter 4 Quality Assurance -- 1. Introduction -- 2. Accreditation -- 3. Internal quality control: harmonised guidelines for internal quality control in analytical chemistry laboratories -- 4. Proficiency testing -- 5. Methods of analysis -- 6. Harmonised guidelines for single-laboratory validation of methods of analysis -- 7. Recovery factors: development of an internationally agreed protocol for the use of recovery factors -- 8. Measurement uncertainty -- 9. Conclusions -- References -- Annex I: Methods of analysis being developed or published by the European Committee for standardisation (CEN) in areas of relevance to this text -- Annex II: Codex guidelines on measurement uncertainty -- References -- Part 3. Molecular Biology Techniques -- Chapter 5 Immunoassays -- 1. Overview of immunoassays -- 2. Principles of immunoassay -- 3. Development of immunoassay for food contaminants -- 4. Conclusion -- References -- Chapter 6 Polymerase chain reaction (PCR) -- 1. Introduction -- 2. Qualitative PCR -- 3. Quantification with PCR -- 4. High-throughput genotyping with PCR -- 5. Analysis of toxicants -- 6. Predictive toxicogenomics -- 7. Conclusions and future trends -- Acknowledgements -- References -- Chapter 7 Analysis of food allergens. Practical applications -- 1. Introduction -- 2. Methods for the detection of allergens -- 3. A selection of food allergens and their detection -- 4. Case studies -- 5. Summary and Outlook -- References -- Chapter 8 Sampling, detection, identification and quantification of genetically modified organisms (GMOs) -- 1. Introduction -- 2. Sampling -- 3. Analyte purification -- 4. Characterising GMOs -- 5. Detecting GMO derived analytes -- 6. Concluding remarks -- References -- Part 4. Screening and Chromatographic Methods -- Chapter 9 Extraction procedures -- 1. Introduction -- 2. Analyte extraction from liquid foodstuff -- 3. Analyte extraction from solid foodstuff -- References -- Chapter 10 Clean-up and fractionation methods -- 1. Introduction -- 2. Nature of interferences -- 3. Methods based on partitioning -- 4. Methods based on chromatography -- 5. Co-distillation/forced volatilisation methods
- Format
- e-Book
- Location
- Online
Generalized Dermatitis in Clinical Practice
https://libcat.nshealth.ca/en/permalink/provcat30893
Susan T. Nedorost.
--Dordrecht:
Springer
, c2012.
- Available Online
- View e-Book
- Location
- Online
Generalized dermatitis is often chronic and debilitating. Many cases are multifactorial, which makes diagnosis and targeted treatment difficult. Although a very common reason for presentation to both dermatologists and primary care physicians, many practitioners fail to control symptoms adequately. Generalized Dermatitis in Clinical Practice summarizes the diagnostic and management options of this complex, multifactorial, and often chronic disease. Distilling a wealth of clinical insight, the …
- Available Online
- View e-Book
- Author
- Nedorost, Susan T
- Responsibility
- Susan T. Nedorost
- Place of Publication
- Dordrecht
- Publisher
- Springer
- Date of Publication
- c2012
- Physical Description
- 1 online resource (xv, 154 p. : 52 ill. in color)
- ISBN
- 9781447128977
- Subjects (MeSH)
- Dermatitis
- Subjects (LCSH)
- Dermatology
- Abstract
- Generalized dermatitis is often chronic and debilitating. Many cases are multifactorial, which makes diagnosis and targeted treatment difficult. Although a very common reason for presentation to both dermatologists and primary care physicians, many practitioners fail to control symptoms adequately. Generalized Dermatitis in Clinical Practice summarizes the diagnostic and management options of this complex, multifactorial, and often chronic disease. Distilling a wealth of clinical insight, the author reviews the pathophysiology and differential diagnosis in the context of patient management. This concise clinical reference is an ideal way for dermatologists, allergists, and primary care physicians to approach the patient suffering from widespread dermatitis.
- Contents
- [Machine generated contents note] 1. Introduction -- Problems with the Definition -- Problems with the Diagnosis and Treatment -- Problems with the Care Team -- Aim of This Work -- References -- 2. Generalized Dermatitis: The Basics -- Introduction -- Definition -- Pathophysiology -- Diagnosis and Management -- Management of Itch -- Dermatitis and the Health Care System -- References -- 3. Role of Irritation in Dermatitis: Implications for Treatment -- Definition -- Irritation and Innate Immunity -- Emollients -- Textiles -- Influence of Innate Immunity on the Adaptive Immune Response -- Nature of the Allergen -- Type of Tissue First Exposed and Concentration of Allergen -- Other Variables -- Corticosteroids -- Role of Irritant Dermatitis in Generalized Dermatitis -- References -- 4. Atopic Dermatitis -- Definition -- Sensitization to Food Protein Allergens -- Sensitization to Pollen Protein Allergens -- Food Pollen Syndromes -- Atopy Patch Tests: Concept -- Atopy Patch Test: Procedure -- Atopy Patch Test: Patient Education -- Avoidance of Topical and Ingestion Exposure to Foods -- Avoidance of Aeroallergens -- Conventional Patch Testing in Atopic Dermatitis -- Role of Commensal Skin Flora in Atopic Dermatitis -- References -- 5. Stasis Dermatitis and Autoeczematization -- Definition -- Management of Stasis Dermatitis -- Secondary Allergic Contact Dermatitis -- Autoeczematization -- Bullous Pemphigoid: An Instructive Mimic -- References -- 6. Generalized Allergic Contact Dermatitis -- Definition -- Causes of Generalized Allergic Contact Dermatitis -- Sensitization to a Common Allergen(s) with More Than One Source, or Polysensitization -- Sensitization to an Allergen with Widespread Skin Contact -- Contact Allergy as a Secondary Diagnosis Along with Other Dermatitis Such as Stasis Dermatitis with Autoeczematization or an Underlying Non-eczematous Skin Disease Such as Psoriasis -- Contact Allergy with Urticarial and Eczematous Response to Airborne Exposure -- Patch Testing for Allergic Contact Dermatitis -- Diagnosis of Generalized Allergic Contact Dermatitis -- Differential Diagnosis -- Scabies: An Instructive Mimic -- References -- 7. Systemic Contact Dermatitis -- Definition -- Mechanism of Systemic Contact Dermatitis -- Diagnosis of Systemic Contact Dermatitis -- Antigen Presenting Cells in Skin Versus Other Mucosae -- Complexity of Food Chemistry and Absorption -- T Regulatory Subtypes and Migration Patterns -- Clinical Clues to Systemic -- Contact Dermatitis -- Contact Urticaria -- Allergic Contact Recall: Ingestion Creates Dermatitis at Prior Patch Test Site -- Mixed Urticarial and Eczematous Reactions -- Vesicular Hand Dermatitis (Dyshidrotic Eczema, Also Known as Pompholyx) -- Baboon Syndrome -- Erythema Multiforme -- Reaction to Implanted Devices -- Dermatitis Herpetiformis: In Instructive Mimic -- References -- 8. Dermatitis Due to Systemic Disease -- Definition -- Hypereosinophilic Syndrome (HES) -- Dermatomyositis -- Cutaneous T Cell Lymphoma -- References -- 9. Diagnosis of Generalized Dermatitis -- Initial Visit -- Patient Education at Start of Visit -- History and Exam -- Initial Tests -- Initial Plans and Preparation for the Second Visit -- Discharge Patient Education -- Diagnostic/Therapeutic Trials -- Interval Treatment -- Referral for Patch Testing -- Evaluating Diagnostic Results -- Patient Education -- One Month Follow Up After Patch Testing -- Recalcitrant Generalized Dermatitis -- References -- 10. Treatment of Generalized Dermatitis -- Demands to Prescribe Systemic Therapy -- Short-Term Treatment for Acute Flares -- Maintenance Treatment for Prevention of Flares -- Long-Term Use of Immuosuppressives -- Prophylaxis for Infectious Complications -- References -- 11. Interdisciplinary Care for Dermatitis -- References.
- Format
- e-Book
- Location
- Online
Kanerva’s Occupational Dermatology
https://libcat.nshealth.ca/en/permalink/provcat44986
Swen Malte John, Jeanne Duus Johansen, Thomas Rustemeyer, Peter Elsner, Howard I. Maibach, editors.
(Third edition)
--Cham:
Springer
, c2020.
- Available Online
- View e-Book
- Location
- Online
This new edition of the principal reference on occupational dermatology provides the most comprehensive updated overview of its clinical management. It contains a number of new and heavily revised chapters, taking into account recent developments in the understanding and clinical management of occupational dermatitis. Since its first publication in 2000, it has served as the main reference on the topic for general and occupational dermatologists, occupational physicians, and health workers in o…
- Available Online
- View e-Book
- Other Authors
- John, Swen Malte
- Johansen, Jeanne Duus
- Rustemeyer, Thomas
- Elsner, Peter
- Maibach, Howard I.
- Responsibility
- Swen Malte John, Jeanne Duus Johansen, Thomas Rustemeyer, Peter Elsner, Howard I. Maibach, editors
- Edition
- Third edition
- Place of Publication
- Cham
- Publisher
- Springer
- Date of Publication
- c2020
- Physical Description
- 1 online resource (4 vol.) : 349 illus., 276 illus. in color
- ISBN
- 9783319686172
- 9783319686158 (Print ed.)
- Subjects (MeSH)
- Dermatitis, Occupational
- Skin Diseases - chemically induced
- Specialty
- Dermatology
- Occupational Health
- Abstract
- This new edition of the principal reference on occupational dermatology provides the most comprehensive updated overview of its clinical management. It contains a number of new and heavily revised chapters, taking into account recent developments in the understanding and clinical management of occupational dermatitis. Since its first publication in 2000, it has served as the main reference on the topic for general and occupational dermatologists, occupational physicians, and health workers in other fields. It provides a comprehensive overview of clinical appearances, epidemiology, diagnostic approaches, contact materials, patient care, and prevention. This third edition of Kanerva’s Occupational Dermatology has been revised and extended to take into account recent developments. The emphasis is very much on evidence-based dermatology, and the coverage is both completely up-to-date and exceptionally detailed. The layout allows for both in-depth reading and quick access to practical information, with the inclusion of concise tables, algorithms, and figures on how to optimize the diagnostic procedure for daily patient management. It continues to ensure that experts and students alike are acquainted with newly emerging conditions and the latest advances.
- Contents
- Volume 1. Part I. General Aspects of Occupational Dermatology -- Part II. Occupational Skin Diseases: Clinical -- Volume 2. Part III. Causative Factors -- Volume 3. Part IV. Diagnosis -- Part V. Therapy -- Part VI. Prognosis -- Part VII. Prevention -- Volume 4. Part VIII. Job Descriptions -- Part IX Chemistry and Concentrations of Patch Test Allergens.
- Format
- e-Book
- Location
- Online
Metal Allergy : From Dermatitis to Implant and Device Failure
https://libcat.nshealth.ca/en/permalink/provcat42833
Jennifer K Chen, Jacob P. Thyssen, editors.
--Cham:
Springer
, c2018.
- Available Online
- View e-Book
- Location
- Online
This volume has been compiled in response to the ongoing revolution in our understanding of metal contact allergy, and the ensuing challenge this has created for clinicians and others to synthesize large amounts of sometimes contradictory data. It opens by providing a comprehensive overview of the use and regulation of metals in our society, metal properties, and available testing methodologies. Common and uncommon metal allergens and sources of exposure are then reviewed in depth, and detailed…
- Available Online
- View e-Book
- Other Authors
- Chen, Jennifer K.
- Thyssen, Jacob P.
- Responsibility
- Jennifer K Chen, Jacob P. Thyssen, editors
- Place of Publication
- Cham
- Publisher
- Springer
- Date of Publication
- c2018
- Physical Description
- 1 online resource (xvii, 578 p.) : 95 illus., 75 illus. in color
- ISBN
- 9783319585031
- 9783319585024 (print ed.)
- 9783319585048 (print ed.)
- Subjects (MeSH)
- Dermatitis, Contact
- Environmental Exposure
- Hypersensitivity
- Metals - adverse effects
- Prostheses and Implants - adverse effects
- Specialty
- Allergy and Immunology
- Dermatology
- Toxicology
- Abstract
- This volume has been compiled in response to the ongoing revolution in our understanding of metal contact allergy, and the ensuing challenge this has created for clinicians and others to synthesize large amounts of sometimes contradictory data. It opens by providing a comprehensive overview of the use and regulation of metals in our society, metal properties, and available testing methodologies. Common and uncommon metal allergens and sources of exposure are then reviewed in depth, and detailed sections are devoted to hypersensitivity to metal implants (which may be associated with device failure and/or dermatitis), metal allergy in select patient populations, and less frequently encountered manifestations of metal allergy. The prevalence of metal allergy in the general population is high: up to 17% of people are allergic to nickel, and 1Çô3% to cobalt and chromium. Environmental sources of metal exposure include jewelry, clothing, electronic devices, coins, leather, diet, and occupational exposure. As metals are ubiquitous, this book will be an indispensable reference text for a wide range of clinicians and investigators, meeting the needs of all who are interested in metal allergy and its diagnosis and management.
- Contents
- Part I. Metal: Overview -- 1. Use of Metals in Our Society -- 2. Metals and Corrosion -- 3. European Standards Developed in Support of the European Union Nickel Directive -- 4. Chromate Testing in Leather: EN ISO 17075 -- 5. Metal Exposure Regulations and Their Effect on Allergy Prevention -- Part II. Metals, Skin, and the Immune System -- 6. Deposition of Metals on the Skin and Quantification of Skin Exposure -- 7. Penetration of Metals Through the Skin Barrier -- 8. Innate Immune System Response in Metal Allergy: Toll-Like Receptors -- 9. Acquired Immunity in Metal Allergy: T Cell Responses -- 10. Metal Allergy and Tolerance Development -- 11. Assessment for Metal Allergy: Patch Testing -- 12. Assessment for Metal Allergy: In Vitro Assays -- Part III. Common Sources of Metal Exposure -- 13. Metals in Everyday Life -- 14. Metals in Tools and the Workplace -- 15. Metals in Cosmetics -- 16. Metals in Coins -- 17. Metals in the Diet -- 18. Prevention of Metal Exposure: Chelating Agents and Barrier Creams -- Part IV. Hypersensitivity to Metallic Implants -- 19. Hypersensitivity to Hip and Knee Implants -- 20. Hypersensitivity to Cardiovascular Implants: Stents -- 21. Hypersensitivity to Cardiovascular Implants: Cardiac Implantable Electronic Devices and Septal Occluders -- 22. Hypersensitivity to Dental Alloys -- 23. Hypersensitivity to Other Implants: Gynecological, Neurovascular, Oculoplastic, Nuss Bars -- 24. Diagnostic Work-Up of Patients with Metal Implant Failure -- Part V. Allergens -- 25. Aluminium -- 26. Beryllium -- 27. Chromium -- 28. Cobalt -- 29. Copper -- 30. Gold -- 31. Mercury -- 32. Nickel -- 33. Palladium -- 34. Titanium -- 35. Other Metals -- Part VI. Metal Allergy in Select Patient Populations -- 36. Metal Allergy and Hand Eczema -- 37. Metal Allergy in Children -- 38. Metal Allergy and Atopic Dermatitis -- 39. Metal Allergy in Asia -- Part VII. Uncommon Manifestations of Metal Allergy -- 40. Metal Allergy and Contact Urticaria -- 41. Metal Allergy and the Lungs -- 42. Metal Allergy and Palmoplantar Pustulosis -- 43. Systemic Nickel Allergy Syndrome.
- Format
- e-Book
- Location
- Online
Molecular Allergy Diagnostics : Innovation for a Better Patient Management
https://libcat.nshealth.ca/en/permalink/provcat41424
Jörg Kleine-Tebbe, Thilo Jakob, editors.
--Cham:
Springer
, 2017.
- Available Online
- View e-Book
- Location
- Online
This book, based on a recent German publication, offers an overview of basic data and recent developments in the groundbreaking field of molecular allergology. It comprehensively explores the origin and structure of single allergen molecules ("components") and their utility in improving the management of type I, IgE-mediated allergic reactions and disorders like allergic respiratory diseases, food allergies, and anaphylaxis. Highly specific testing, called component-resolved diagnostics, aims t…
- Available Online
- View e-Book
- Other Authors
- Kleine-Tebbe, Jörg
- Jakob, Thilo
- Responsibility
- Jörg Kleine-Tebbe, Thilo Jakob, editors
- Place of Publication
- Cham
- Publisher
- Springer
- Date of Publication
- 2017
- Physical Description
- 1 online resource (xx, 531 pages) : 112 illus., 100 illus. in color
- ISBN
- 9783319424996
- 9783319424989 (print ed.)
- Subjects (MeSH)
- Allergens - immunology
- Biomarkers - analysis
- Hypersensitivity - diagnosis
- Immunoglobulin E - immunology
- Molecular Diagnostic Techniques
- Sensitivity and Specificity
- Abstract
- This book, based on a recent German publication, offers an overview of basic data and recent developments in the groundbreaking field of molecular allergology. It comprehensively explores the origin and structure of single allergen molecules ("components") and their utility in improving the management of type I, IgE-mediated allergic reactions and disorders like allergic respiratory diseases, food allergies, and anaphylaxis. Highly specific testing, called component-resolved diagnostics, aims to identify and utilize single molecules. Over 200 single allergens from plant or animal sources have been applied to single or multiplex laboratory testing for the presence of allergen-specific IgE. This leap in assay sensitivity and specificity has led to three major advances in patient management: discrimination between primary allergic sensitization and complex cross-reactivity, recognition of IgE profiles for certain allergens and identification of patients most likely to benefit from allergen-specific immunotherapy. The book discusses in detail the benefits and limitations of this 21st century technology, and offers suggestions for the use of molecular allergology in routine clinical practice. It is a "must read" for physicians treating allergic patients as well as scientists interested in natural allergic molecules and their interactions with the human immune system.
- Contents
- Part I: Protein Families and Relationships -- 1. Introduction to Molecular Allergology: Protein Families, Databases, and Potential Benefits -- 2. Bet v 1 and its Homologs: Triggers of Tree-Pollen Allergy and Birch Pollen-Associated Cross-Reactions -- 3. The Concept of Pollen Panallergens: Profilins and Polcalcins -- 4. Stable Plant Food Allergens I: Lipid-Transfer Proteins -- 5. Stable Plant Food Allergens II: Storage Proteins -- 6. Cross-Reactive Carbohydrate Determinants: Diagnostic and Clinical Relevance -- Part II: Test Systems, Singleplex Analysis and Multiplex Analysis -- 7. Molecular Allergy Diagnostics Using IgE Singleplex Assays: Methodological and Practical Considerations -- 8. Spiking with Recombinant Individual Allergens for Improvement of Allergen Extracts -- 9. Molecular Allergy Diagnostics Using Multiplex Assays -- Part III: Marker Allergens -- 10. Marker Allergens and Panallergens in Tree and Grass Pollen Allergy -- 11. Marker Allergens of Weed Pollen: Basic Considerations and Diagnostic Benefits in Routine Clinical Practice -- 12. Molecular Diagnostics for Peanut Allergy -- 13. Molecular Diagnostics for Tree Nut Allergy -- 14. Molecular Diagnostics of Allergy to Fruits and Vegetables -- 15. Cow’s Milk and Hen’s Egg Allergy: What Do Molecular-Based Allergy Diagnostics Have to Offer? -- 16. Molecular and Extract-Based Diagnostics in Meat Allergy -- 17. Molecular Diagnostics in Food-Dependent Exercise-Induced Anaphylaxis -- 18. Benefits and Limitations of Recombinant Allergens in Diagnostics of Insect Venom Allergy -- 19. Molecular Diagnostics in Allergy to Mammals -- 20. Extract-Based and Molecular Diagnostics in Fish Allergy -- 21. Allergens and Molecular Diagnostics of Shellfish Allergy -- 22. Allergens, Diagnostics, and Therapeutic Aspects in House Dust Mite Allergy -- 23. Cockroach, Tick, Storage Mite, and Other Arthropod Allergies: Molecular Aspects -- 24. Mold Allergens and Their Importance in Molecular Allergy Diagnosis -- 25. Latex Allergens: Source of Sensitization and Single Allergens -- Part IV: Designer Allergens, Hypoallergens and Fusion Allergens -- 26. Recombinant Allergens in Specific Immunotherapy -- 27. Definition and Design of Hypoallergenic Foods.
- Format
- e-Book
- Location
- Online
Occupational and Environmental Skin Disorders : Epidemiology, Current Knowledge and Perspectives for Novel Therapies
https://libcat.nshealth.ca/en/permalink/provcat43052
Nlandu Roger Ngatu, Mitsunori Ikeda, editors.
--Singapore:
Springer
, c2018.
- Available Online
- View e-Book
- Location
- Online
This book provides cutting-edge information on the epidemiology, etiology and pathophysiology of several prevalent occupational and environmental skin diseases (OSD/ESD), with a particular focus on skin health safety issues, risk factors, preventive measures and recent advances in the management of these diseases. It also highlights recent discoveries and developments concerning novel therapeutic agents for inflammatory OSD, especially findings that are supported by clinical data and have the p…
- Available Online
- View e-Book
- Other Authors
- Ngatu, Nlandu Roger
- Ikeda, Mitsunori
- Responsibility
- Nlandu Roger Ngatu, Mitsunori Ikeda, editors
- Place of Publication
- Singapore
- Publisher
- Springer
- Date of Publication
- c2018
- Physical Description
- 1 online resource (xvi, 168 p.) : 47 illus., 43 illus. in color
- ISBN
- 9789811087585
- 9789811087578 (print ed.)
- 9789811087592 (print ed.)
- 9789811342318 (print ed.)
- Abstract
- This book provides cutting-edge information on the epidemiology, etiology and pathophysiology of several prevalent occupational and environmental skin diseases (OSD/ESD), with a particular focus on skin health safety issues, risk factors, preventive measures and recent advances in the management of these diseases. It also highlights recent discoveries and developments concerning novel therapeutic agents for inflammatory OSD, especially findings that are supported by clinical data and have the potential to transform conventional prophylactic and therapeutic approaches. For example, despite their increasing prevalence, the management of allergic skin diseases is sometimes challenging, mainly due to limited treatment choices. In several countries, steroids are the only treatment used. However, in cases of contraindications, adverse effects or unsatisfactory steroidal therapies, alternative treatments are indispensable. As such, an understanding of promising anti-allergic agents enhances allergy research and could eventually lead to novel alternative therapeutic and adjuvant remedies, which are of the utmost importance. This book offers a valuable resource for researchers, graduate students and practitioners in the field of public health in general, especially those working in environmental and occupational medicine, as well as physicians.
- Contents
- 1. Introduction -- PART I. SKIN IRRITANTS, SENSITIZERS AND CARCINOGENS -- 2. Skin Function and Occupational Cutaneous Hazards -- PART II. ENVIRONMENTAL AND OCCUPATIONAL ECZEMATOUS SKIN DISORDERS -- 3. Atopic dermatitis -- 4. Occupational Contact -- 5. Quality of Work Environment and Frequency of Work-related Dermatitis in Dust-exposed African Informal Coltan Miners -- 6. Occupational Cement Dermatitis and Cement -- 7. Alternative Therapies for Eczematous Environmental and Occupational Skin Diseases and their Anti-inflammatory Mechanisms -- 8. Sacran: Novel Natural Sulfated Polysaccharide as Antiallergic Skincare Biomaterial for Atopic Dermatitis -- 9. Experimental Anti-Allergic and Immunomodulatory Effects of Vernonia amygdalina-derived Vernodalin and Plant Extracts -- 10. Clinical Anti-Allergic Effects of Vernonia Amygdalina Leaf Extracts -- PART III. FUNGAL, NEGLECTED SEASONAL, EPIDEMIC AND OTHER ENVIRONMENTAL KIN DISORDERS -- 11. Common Environmental Dermatomycoses -- 12. Sarcoptic Skin Disease (or Scabies) -- 13. Frequency and Clinical Features of Sarcoptic Skin Disease in Congolese Schoolchildren -- 14. Paederus Dermatitis: Environmental Risk Factors, Clinical Features and Management -- 15. Overview on other Environmental Skin Disorders.
- Format
- e-Book
- Location
- Online
Patch Testing and Prick Testing : A Practical Guide Official Publication of the ICDRG
https://libcat.nshealth.ca/en/permalink/provcat45118
Jean-Marie Lachapelle, Howard I. Maibach, editors.
(Fourth edition)
--Cham:
Springer
, c2020.
- Available Online
- View e-Book
- Location
- Online
The fourth edition of this important book, which includes additional color illustrations, has been extensively revised, updated, and expanded to reflect the most recent developments. These include advances in patch testing methodology, in particular the new chambers that are appearing on the market, revision of the baseline series of patch tests to reflect the latest evidence-based work, and additional testing procedures. Other additions include sections on key allergens and concentrations, wit…
- Available Online
- View e-Book
- Other Authors
- Lachapelle, Jean-Marie
- Maibach, Howard I.
- Other Authors
- International Contact Dermatitis Research Group
- Responsibility
- Jean-Marie Lachapelle, Howard I. Maibach, editors
- Edition
- Fourth edition
- Place of Publication
- Cham
- Publisher
- Springer
- Date of Publication
- c2020
- Physical Description
- 1 online resource (xxii, 246 p.) : 98 illus., 93 illus. in color
- ISBN
- 9783030270995
- 9783030270988 (Print ed.)
- 9783030271008 (Print ed.)
- 9783030271015 (Print ed.)
- Specialty
- Allergy and Immunology
- Diagnosis
- Abstract
- The fourth edition of this important book, which includes additional color illustrations, has been extensively revised, updated, and expanded to reflect the most recent developments. These include advances in patch testing methodology, in particular the new chambers that are appearing on the market, revision of the baseline series of patch tests to reflect the latest evidence-based work, and additional testing procedures. Other additions include sections on key allergens and concentrations, with the result is a superb guide to the current management of positive and negative patch test and prick test reactions that will be invaluable for all practicing dermatologists, from the beginner to the well-trained expert. The fourth edition continues the tradition of partnering with the ICDRG (International Contact Dermatitis Research Group). The ICDRG was formed in 1966 to promote the understanding of contact dermatitis. It has had major roles in the standardization of patch testing and the facilitation of regular scientific meetings, for over forty years and thirty five years respectively. It has also been involved in the authorship of a number of publications on contact dermatitis. Both Drs. Maibach and Lachapelle are members and the ICDRG is now comprised of representatives from all over the world, and currently includes members from Belgium, Sweden, Denmark, the United Kingdom, USA, Germany, Singapore, Korea, India, Japan, Canada, Uruguay and Australia. From the reviews of the previous editions: The aim is to balance brevity and clarity with sufficient details for beginners in the field of diagnostic patch and prick testing. … the book also will be of use to dermatology residents or anyone wishing to gain better knowledge of contact dermatitis. … There are many high-quality photographs and useful algorithms and tables. … It is clearly and concisely written and will serve as an indispensable guide for any dermatologist interested in contact dermatitis. (Renata H. Mullen, Doody’s Review Service, August, 2009).
- Contents
- Part I. Patch Testing -- 1. Pathophysiology of Allergic and Irritant Contact Dermatitis -- 2. Diseases for Which Patch Testing Is Recommended: Patients Who Should Be Investigated -- 3. Patch Testing Methodology -- 4. Baseline Series of Patch Tests -- 5. Photopatch Testing -- 6. The T.R.U.E. Test® Methodology -- 7. Additional Testing Procedures and Spot Tests -- 8. Clinical Relevance of Patch Test Reactions -- 9. Atopic Dermatitis, Irritant Contact Dermatitis, and Allergic Contact Dermatitis -- Part II. Prick Testing -- 10. Spectrum of Diseases for Which Prick Testing and Open (Non-prick) Testing Are Recommended: Patients Who Should Be Investigated -- 11. Methodology of Open (Non-prick) Testing, Prick Testing, and Its Variants -- Part III. Testing in Cutaneous Systemic Immune-Related Adverse Drug Reactions: Interest and Limitations -- 12. Testing Procedures in Cutaneous Systemic Immune-Related Adverse Drug Reactions -- Appendices -- Appendix A: Additional Series of Patch Tests -- Appendix B: The International Contact Dermatitis Research Group -- Appendix C: A List of Companies Producing and/or Distributing Patch and/or Prick Test Materials and/or Allergens.
- Format
- e-Book
- Location
- Online
Patch testing tips : recommendations from the ICDRG
https://libcat.nshealth.ca/en/permalink/provcat33722
Jean-Marie Lachapelle, Magnus Bruze, Peter U. Elsner, editors.
--Heidelberg:
Springer
, c2014.
- Available Online
- View e-Book
- Location
- Online
This book is a compendium of tips on many different aspects of patch testing based on the recommendations of the International Contact Dermatitis Research Group (ICDRG), which is the reference group for all dermato-allergologists. It is intended to complement the book Patch Testing and Prick Testing: A Practical Guide by J.-M. Lachapelle and H. Maibach, which is an official publication of the ICDRG now in its third edition. Among the wide variety of topics covered are pitfalls, legal aspects, p…
- Available Online
- View e-Book
- Corporate Author
- International Contact Dermatitis Research Group
- Other Authors
- Lachapelle, Jean-Marie
- Bruze, Magnus
- Elsner, Peter
- Responsibility
- Jean-Marie Lachapelle, Magnus Bruze, Peter U. Elsner, editors
- Place of Publication
- Heidelberg
- Publisher
- Springer
- Date of Publication
- c2014
- Physical Description
- 1 online resource (x, 171 pages)
- ISBN
- 9783642453953 (electronic bk.)
- 3642453953 (electronic bk.)
- 3642453945 (print)
- 9783642453946 (print)
- Subjects (MeSH)
- Patch Tests
- Subjects (LCSH)
- Skin - Diseases - Treatment
- Dermatology
- Specialty
- Allergy and Immunology
- Diagnosis
- Notes
- Augmentation of Patch testing and prick testing : a practical guide : offiical publication of the ICDRG / Jean-Marie Lachapelle, Howard I. Maibach. 3rd ed. c2012.
- Abstract
- This book is a compendium of tips on many different aspects of patch testing based on the recommendations of the International Contact Dermatitis Research Group (ICDRG), which is the reference group for all dermato-allergologists. It is intended to complement the book Patch Testing and Prick Testing: A Practical Guide by J.-M. Lachapelle and H. Maibach, which is an official publication of the ICDRG now in its third edition. Among the wide variety of topics covered are pitfalls, legal aspects, patch testing with ultrasonic bath extracts, the role of patch testing in occupational contact dermatitis and atopic dermatitis, semi-open tests, the implications of a negative test, patch testing validity, selection of extra allergens and patch testing in the tropics. Many illustrations are included and all information is completely up-to-date. This book will be of value to all practicing dermatologists.
- Contents
- 1. Patch Testing: A Historical and Current Perspective -- 2. Making a Diagnosis -- 3. Pitfalls and Errors in Patch Testing: Suggestions for Quality Assurance -- 4. The Validity of Patch Testing -- 5. “Doctor, Why Are My Patch Tests Negative?” -- 6. How to Select Extra Allergens and Problematic Allergens -- 7. Occupational Allergic Contact Dermatitis: New Facets -- 8. Patch Testing and Atopic Eczema -- 9. Occupational Airborne Contact Dermatitis: A Realm for Specific Diagnostic Procedures and Tips -- 10. Proxy Contact Dermatitis, or Contact Dermatitis “by Proxy” (Consort or Connubial Dermatitis) -- 11. Semi-open (or Semi-occlusive) Tests -- 12. The Use of Ultrasonic Bath Extracts in the Diagnostics of Contact Allergy and Allergic Contact Dermatitis -- 13. Patch Testing in the Tropics -- 14. Contact Dermatitis in a Rapidly Changing Society: Experiences in Korea -- 15. Immediate-Type Testing: Immunologic Contact Urticaria and Immunologic Contact Urticaria Dermatitis.
- Format
- e-Book
- Location
- Online
Pollen Allergy in a Changing World : A Guide to Scientific Understanding and Clinical Practice
https://libcat.nshealth.ca/en/permalink/provcat42897
Jae-Won Oh.
--Singapore:
Springer
, c2018.
- Available Online
- View e-Book
- Location
- Online
This book presents the latest scientific knowledge on the role of pollens in triggering respiratory allergies and offers up-to-date guidance on the diagnosis, treatment, and prevention of pollen allergy. Detailed information is supplied on allergenic plants and on the complex associations between pollen allergy and local weather conditions, air pollution, and climate change. Readers will learn how climate change in particular is impacting on pollen concentrations, pollen allergenicity, the poll…
- Available Online
- View e-Book
- Author
- Oh, Jae-Won
- Responsibility
- Jae-Won Oh
- Place of Publication
- Singapore
- Publisher
- Springer
- Date of Publication
- c2018
- Physical Description
- 1 online resource (xiii, 181 p.) : 135 illus., 113 illus. in color
- ISBN
- 9789811054990
- 9789811054983 (print ed.)
- 9789811055003 (print ed.)
- Subjects (MeSH)
- Allergens - adverse effects
- Pollen - adverse effects
- Pollen - anatomy & histology
- Rhinitis, Allergic, Seasonal - diagnosis
- Rhinitis, Allergic, Seasonal - therapy
- Specialty
- Allergy and Immunology
- Abstract
- This book presents the latest scientific knowledge on the role of pollens in triggering respiratory allergies and offers up-to-date guidance on the diagnosis, treatment, and prevention of pollen allergy. Detailed information is supplied on allergenic plants and on the complex associations between pollen allergy and local weather conditions, air pollution, and climate change. Readers will learn how climate change in particular is impacting on pollen concentrations, pollen allergenicity, the pollen season, and plant and pollen distribution. A further important feature is the presentation of a forecasting system for allergenic pollens that takes into account a variety of meteorological factors and is designed to be of benefit to allergy patients. This up-to-date scientific knowledge is complemented by clear guidance on all aspects of the management of pollen allergy. The closing chapters address global trends in allergy research and future prospects for pollen allergy. The book will appeal both to researchers seeking state of the art information on the topic and to clinicians wishing to optimize patient care.
- Contents
- I. Introduction -- 1. What is an allergy? -- 2. Why doses a person become allergic? -- 3. Factors influencing clinical significance of aeroallergens -- 4. The importance of pollen counts -- 5. Why collect and identify pollens? -- II. Pollen collection -- 1. Purpose of standardized air sampling -- 2. Samplers -- 3. Pollen Sampling Methods -- 4. Operation -- III. Pollen identification -- 1. The appearance of airborne grass pollen grains -- 2. Other airborne pollen grains -- IV. Allergenic pollen images -- 1. Single grains (Monads) without apertures -- 2. Single grains with furrows -- 3. Single grain with apertures -- V. Classification of Allergenic plants -- 1. Anatomy of plant -- 2. Taxonomy -- VI. Pollen allergy and meteorological factors -- 1. Effects of weather on allergen load and pollen potency -- 2. Pollen calendars -- 3. Effects of weather on pollen flight -- 4. Forecast the pollen concentration -- VII. How does climate change influence allergenic pollen? -- 1. Thunderstorm-related asthma -- 2. Mechanisms for thunderstorm asthma -- VIII. How to diagnose the pollen allergy -- 1. Skin Prick Test -- 2. Intradermal Skin Test -- 3. Allergy Blood Tests -- IX. How to treat and prevent the pollen allergy.
- Format
- e-Book
- Location
- Online
Polycystic Kidney Disease : Translating Mechanisms into Therapy
https://libcat.nshealth.ca/en/permalink/provcat42991
edited by Benjamin D. Cowley, Jr., John J. Bissler.
--New York, NY:
Springer
, c2018.
- Available Online
- View e-Book
- Location
- Online
This comprehensive guide to polycystic kidney disease captures the growing knowledge of this common, potentially-fatal and hereditary disease. The first two sections of the book provide an overview of PKD gene structures, mutations and pathophysiologic mechanisms. This is followed by chapters focused on PKD's clinical features, including renal and extrarenal manifestations, and appropriate management of patients. The final section covers current clinical trials and emerging therapies in PKD. Au…
- Available Online
- View e-Book
- Other Authors
- Cowley, Jr., Benjamin D.
- Bissler, John J.
- Responsibility
- edited by Benjamin D. Cowley, Jr., John J. Bissler
- Place of Publication
- New York, NY
- Publisher
- Springer
- Date of Publication
- c2018
- Physical Description
- 1 online resource (xiii, 273 p.) : 62 illus., 42 illus. in color
- ISBN
- 9781493977840
- 9781493977826 (print ed.)
- 9781493977833 (print ed.)
- Subjects (MeSH)
- Allergens - adverse effects
- Pollen - adverse effects
- Pollen - anatomy & histology
- Rhinitis, Allergic, Seasonal - diagnosis
- Rhinitis, Allergic, Seasonal - therapy
- Specialty
- Nephrology
- Abstract
- This comprehensive guide to polycystic kidney disease captures the growing knowledge of this common, potentially-fatal and hereditary disease. The first two sections of the book provide an overview of PKD gene structures, mutations and pathophysiologic mechanisms. This is followed by chapters focused on PKD's clinical features, including renal and extrarenal manifestations, and appropriate management of patients. The final section covers current clinical trials and emerging therapies in PKD. Authored by experts in the field, this book provides the clinician and researcher with critical information on basic and translational science and clinical approaches in one concise resource.
- Contents
- PART 1. POLYCYSTIC KIDNEY DISEASE GENES & PROTEINS -- 1. Classical Polycystic Kidney Disease (PKD): Gene Structures and Mutations and Protein Structures and Functions -- 2. Bardet-Biedl Syndrome -- 3. Cystic Kidney Diseases Associated with Increased Cancer Risk: Tuberous Sclerosis Complex, Von Hippel Lindau, and Birt Hogg Dub© -- PART 2. POLYCYCSTIC KIDNEY DISEASE: MECHANISMS OF DISEASE -- 4. Aberrant Cellular Pathways in PKD -- 5. Cilia and Polycystic Kidney Disease -- 6. The Role of Inflammation and Fibrosis in Cystic Kidney Disease -- PART 3. CLINICAL FEATURES -- 7. Imaging-based Diagnosis of Autosomal Dominant Polycystic Kidney Disease -- 8. Renal Structural Involvement in Autosomal Dominant Polycystic Kidney Disease: Cyst Growth and Total Kidney Volume: Lessons from the Consortium for Radiologic Imaging of Polycystic Kidney Disease (CRISP) -- 9. Renal Complications: Pain, Infection and Nephrolithiasis -- 10. ADPKD Extrarenal Manifestations: Polycystic Liver Disease -- 11. Extrarenal Manifestations of Autosomal Dominant Polycystic Kidney Disease -- PART 4. CLINICAL TRIALS AND EMERGING THERAPIES -- 12. Role of Renin- Angiotensin- Aldosterone System Inhibition in Autosomal Dominant Polycystic Kidney Disease -- 13. Vasopressin Receptor Antagonism -- 14. End-stage Renal Disease in Patients with Autosomal Dominant Polycystic Kidney Disease -- 15. Polycystic Kidney Disease: Translating Mechanisms into Therapy Management of ADPKD Today.
- Format
- e-Book
- Location
- Online
