This book provides a concise overview over the pathology of retinal angiogenic diseases and explains why anti-angiogenic therapy is effective in so many patients. The reader is guided through the various clinical indications for anti-angiogenic therapy and made aware of its merits as well as current challenges and limitations. It is explained how, since its introduction for the treatment of exudative age-related macular degeneration in 2006, anti-angiogenic therapy has revolutionized the way in…
This atlas depicts and describes catheter-based interventions across the entire pediatric age range, from fetal life through to early adulthood, with the aim of providing an illustrated step-by-step guide that will help the reader to master these techniques and apply them in everyday practice. Clear instruction is offered on a wide range of procedures, including vascular access, fetal interventions, valve dilatation, angioplasty, stent implantation, defect closure, defect creation, valve implan…
Recent advances in the understanding of brain functions are reviewed in this text, along with how neurobiological research and brain imaging contributes to identifying and treating neurologic and psychiatric disorders. Chapters focus on consciousness, memory, emotions, language, communication, trauma, pain and resilience, while exploring how stressful events impact mental health and interrupt the continuity of one's sense of self. Clinical vignettes of patients with neurological and mental affe…
Congenital cardiology continues to advance at a rapid pace, with recent decades witnessing exceptional growth in the number and range of catheter-based interventions. This handbook is an ideal, up-to-date guide to the application of these procedures across the entire patient age range, from fetal life through to adulthood. Clear instruction is offered on techniques of vascular access, valve dilatation, angioplasty, stent implantation, defect closure, defect creation, pulmonary valve implantatio…
Now in a revised and expanded second edition, this practical text utilizes the most current evidence and knowledge of articular cartilage as the basis for clinical interventions for cartilage repair and restoration, combining an overview of clinical research and methodologies with clinical cases to help guide the orthopedic treatment and care of patients presenting with cartilage issues. Carefully updated chapters discuss the state-of-the-art in cartilage anatomy, defects and imaging, current t…
Attempting to bridge the gap between the science and art of cartilage restoration, Cartilage Restoration: Practical Clinical Applications combines an overview of clinical research and methodologies with clinical cases to help guide the orthopedic treatment and care of patients presenting with cartilage issues. With chapters written by internationally-renowned orthopedic surgeons, topics include an overview of current surgical options, debridement and marrow stimulation, autograft plug transfer,…
This book presents clinicopathological insights into common genitourinary diseases, especially those of neoplastic nature, and introduces experiential learning based on case presentations (case-based learning). One of the tasks that trainees face is converting the extensive amount of data into medical experience. Using successive microscopic images, the book gradually and analytically presents diagnostic procedures for the genitourinary system (kidney, urinary bladder, prostate gland and testis…
This book presents more than 120 cases covering all areas of reconstructive surgery. Divided into six parts (Head/Neck, Upper Extremity, Lower Extremity, Trunk, Breast and Lymphedema), it guides the reader through the difficult path of problem diagnosis, analysis and decision-making, presenting concrete steps and techniques for the successful management of patients with specific reconstructive needs. Each full-color case starts with a patient profile and continues with the diagnosis, key decisi…
In this thesis, a tracking system was developed by modifying an add-on collimator, the Siemens Moduleaf, for realtime applications in radiotherapy. As the add-on collimator works almost completely autonomously of the linear accelerator (LinAc), no modifications to the latter were necessary. The adaptations to the Moduleaf were mainly software-based. In order to reduce the complexity of the system, outdated electronic parts were replaced with newer components where practical. Verification was pe…
This book provides a comprehensive overview of the practical aspects of contrast echocardiography. It also covers all the material in the guidelines published by the American Society of Echocardiography (ASE) in 2018 and the recommendations set out by the European Association of Cardiovascular Imaging (EACVI) in 2017. Contrast echocardiography at present is only used in 5-10% of cases, but this is expected to grow rapidly following the recommendations of the ASE and EACVI. The chapters cover th…
Interventional radiology is an indispensable and still expanding area of modern medicine that encompasses numerous diagnostic and therapeutic procedures. Cross-sectional imaging modalities such as computed tomography (CT) and magnetic resonance (MR) have emerged as important techniques for non-vascular interventions, including percutaneous biopsy, drainage, ablation, and neurolysis. Various organs, diseases, and lesions can be approached in this way, permitting the treatment and management of t…
This book presents a collection of short biographies and works of the pioneers in pathology, together with a brief history of the European Society of Pathology and the New York Pathological Society. Detailed information is provided on the development and current status of immunohistochemistry, light microscopy and dry preparations in medical education. The alphabetically arranged entries allow readers to quickly and easily find the information they need.