This comprehensive book provides not only the stages in the development of this unique and specialized field but also updates on the current state of research and development of apolipoprotein mimetics as therapeutic modalities for various lipid-mediated disorders. The book consists of 11 chapters all written by leading scientists from well-reputed laboratories in the USA. After an introduction by Dr. Godfrey Getz, Professor of Medicine at the University of Chicago and the Associate Editor of t…
As our knowledge about arterial disease is greatly expanding, the aim of this book is to explore all aspects of arterial pathology, including classification, clinical manifestations, pathogenesis, and therapeutic options. The discussion of pathophysiologic mechanisms of arterial disease is wide ranging, encompassing hemodynamic, metabolic, humoral, inflammatory, genetic and environmental factors. Particular emphasis is placed on recent concepts, such as: the role of age-associated arterial alte…
This book covers all aspects of the prevention, diagnosis, and treatment of stroke, offering an integrated perspective that will be relevant to a range of specialists. Extensive consideration is given to the different methods of stroke prevention and arterial revascularization, with up-to-date information on pharmacological measures and clear presentation of endovascular stent placement procedures and surgical techniques, including those involving the carotid artery, vertebral artery, and aorti…
This book presents up-to-date information on how to assess early preclinical alterations in the heart, the small and large arteries and the kidney in the general and the hypertensive population, using the most sensitive, specific and cost-effective techniques. A wide variety of techniques are discussed, with careful attention to the latest developments. For each organ, evidence is documented regarding the prevalence of organ damage. Information is provided on the potential induction of regressi…
Despite recent advances in the diagnosis and treatment of symptomatic atherosclerosis, available traditional screening methods for early detection and treatment of asymptomatic coronary artery disease are grossly insufficient and fail to identify the majority of victims prior to the onset of a life-threatening event. In Asymptomatic Atherosclerosis: Pathophysiology, Detection and Treatment, Dr. Morteza Naghavi and leading authorities from the Society for Heart Attack Prevention and Eradication …
Atherosclerosis: Clinical Perspectives Through Imaging is aimed at practicing clinicians and relies on didactic tabular and bullet points and a host of fine imagery describing the common features of the imaging of atherosclerosis, enabling the reader to understand more about the advantages and limitations of each modality in investigating athersclosis. Edited by and contributed to by a host of international experts in cardiac imaging, this book is a must read by all who image the heart.
This book provides new perspectives on the pathogenesis of atherosclerosis. Chapters cover atherosclerosis risk factors, the effect of growth and aging on vascular architecture, and the crucial role the microvasculature plays in atherosclerosis development. Microvascular dysfunction would explain why the well-known risk factors actually put individuals at higher risk. This pathomechanism would also hold true not only for obstructive atheroma formation but also for aneurysmal dilatation as well …
This atlas is a practical and fully illustrated guide to the use of intravascular OCT in diagnosis and treatment of coronary artery disease. It consists of two parts. The first part of the book provides a systematic introduction to coronary imaging with OCT. It describes how to interpret images and describes abnormal findings seen in atherosclerosis, complications after intervention, and stent assessment. The second part of the book presents real-life case studies that show how OCT is used in c…
The newly updated and expanded Atlas of Nuclear Cardiology, Fourth Edition provides physicians and trainees with the most up-to-date information in a rapidly changing field. In addition to beautifully rendered color illustrations, the atlas emphasizes key points with a multitude of diagnostic algorithms and schematic diagrams integrated with nuclear cardiology procedures. Relevant for the clinical practice of nuclear cardiology, each chapter focuses on material of practical merit. The book give…
Behçet's syndrome can reasonably be considered a unique entity among diseases of the immune system for several reasons: It has specific features and, uniquely among the immune system pathologies, represents a link between autoimmune diseases, systemic vasculitis, and autoinflammatory diseases. In addition, it is of interest to a variety of specialists, including immunologists, rheumatologists, dermatologists, and ophthalmologists, and requires a complex multidisciplinary approach. Many aspects …
Experimental studies in the field of cardiac valve biology are now demonstrating that the cardiac valve disease process is an active biology with risk factors analogous to vascular risk factors. Understanding the risk factors is also evolving rapidly, giving physicians and scientists insight into the cellular mechanisms and raising the possibility of treating these valve lesions with other options besides surgical valve repair. Our knowledge of right-sided valve lesions is also rapidly becoming…
This book examines the links between physical activity (PA), cardiorespiratory fitness (CRF), and cardiovascular and metabolic diseases. It presents an overview of the role of PA and CRF in the prevention and management of risk factors associated with cardiometabolic diseases such as hypertension, peripheral vascular disease, stroke, type 2 diabetes, metabolic syndrome, dyslipidemia, obesity, and atherosclerosis. In addition, it explores how these risks vary with different populations such as t…
This book provides a balanced presentation of the fundamental principles of cardiovascular biomechanics research, as well as its valuable clinical applications. Pursuing an integrated approach at the interface of the life sciences, physics and engineering, it also includes extensive images to explain the concepts discussed. Cardiovascular biomechanics encompasses the relationship between the mechanics of the cardiovascular system and biological function in health and disease, and it is increasi…