Skip header and navigation
Did you mean artherosclerosis?

Narrow By

102 records – page 1 of 6.

Apolipoprotein Mimetics in the Management of Human Disease

https://libcat.nshealth.ca/en/permalink/provcat39279
G.M. Anantharamaiah, Dennis Goldberg, editors. --Cham: Springer International Publishing : Imprint: Adis , c2015.
Available Online
View e-Book
Location
Online
This comprehensive book provides not only the stages in the development of this unique and specialized field but also updates on the current state of research and development of apolipoprotein mimetics as therapeutic modalities for various lipid-mediated disorders. The book consists of 11 chapters all written by leading scientists from well-reputed laboratories in the USA. After an introduction by Dr. Godfrey Getz, Professor of Medicine at the University of Chicago and the Associate Editor of t…
Available Online
View e-Book
Other Authors
Anantharamaiah, G.M
Goldberg, Dennis
Responsibility
G.M. Anantharamaiah, Dennis Goldberg, editors
Place of Publication
Cham
Publisher
Springer International Publishing : Imprint: Adis
Date of Publication
c2015
Physical Description
1 online resource (xxi, 182 p. : 42 illus., 22 illus. in color)
ISBN
9783319173504
9783319173498 (print ed.)
Subjects (MeSH)
Apolipoproteins - therapeutic use
Biomimetics
Abstract
This comprehensive book provides not only the stages in the development of this unique and specialized field but also updates on the current state of research and development of apolipoprotein mimetics as therapeutic modalities for various lipid-mediated disorders. The book consists of 11 chapters all written by leading scientists from well-reputed laboratories in the USA. After an introduction by Dr. Godfrey Getz, Professor of Medicine at the University of Chicago and the Associate Editor of the Journal Lipid Research, the book presents a narration of how a theory can lead to the discovery of treatment modalities to several devastating diseases such as diabetes, Alzheimer's disease, arthritis; asthma; atherosclerosis, chronic rejection of transplanted hearts and cancer. Present therapies for most of these diseases are not adequate. Using the models of two long anti-atherogenic and anti-inflammatory proteins (apolipoprotein A-I and apolipoprotein E with 243 and 299 amino acids, respectively) short mimetic peptides of 18 to 28 amino acid residues in length, which can be produced either synthetically or genetically in edible fruits and vegetables, have been shown to exert profound biological effects in a large number of animal models of diseases. The book also presents novel ideas, highly unexpected mechanisms of action in animal models and even in initial clinical studies in humans, which can lead to additional improvements in basic and clinical research in biological science. All the chapters are written by experts in their respective fields who have contributed immensely to the literature. This is the first compendium of this growing field presented in the form of a book.
Contents
1. HDL and the Amphipathic Helix -- 2. ApoA-I mimetic peptides: A review of the present status -- 3. Apolipoprotein Mimetic Peptides for Stimulating Cholesterol Efflux -- 4. ApoA-I Mimetic Peptides and Diabetes -- 5. Apolipoprotein A-I mimetic peptides in Mouse Models of Cancer -- 6. Effects of ApoA-I mimetic peptide L-4F in LPS-mediated inflammation -- 7. Apolipoprotein mimetics in the amelioration of respiratory inflammation -- 8. Regulation of Macrophage Polarity by HDL, Apolipoproteins And Apolipoprotein Mimetic Peptides -- 9. Apolipoprotein E & Atherosclerosis: Beyond Lipid Effects -- 10. Apolipoprotein E mimetic peptides: Cholesterol dependent and independent properties -- 11. Apolipoprotein-E and Mimetics as Targets and Therapeutics for Alzheimer's Disease.
Format
e-Book
Location
Online
Less detail

Arterial Disorders : Definition, Clinical Manifestations, Mechanisms and Therapeutic Approaches

https://libcat.nshealth.ca/en/permalink/provcat39194
Adel Berbari, Giuseppe Mancia, editors. --Cham: Springer , c2015.
Available Online
View e-Book
Location
Online
As our knowledge about arterial disease is greatly expanding, the aim of this book is to explore all aspects of arterial pathology, including classification, clinical manifestations, pathogenesis, and therapeutic options. The discussion of pathophysiologic mechanisms of arterial disease is wide ranging, encompassing hemodynamic, metabolic, humoral, inflammatory, genetic and environmental factors. Particular emphasis is placed on recent concepts, such as: the role of age-associated arterial alte…
Available Online
View e-Book
Other Authors
Berbari, Adel
Mancia, Giuseppe
Responsibility
Adel Berbari, Giuseppe Mancia, editors
Place of Publication
Cham
Publisher
Springer
Date of Publication
c2015
Physical Description
1 online resource (ix, 431 p. : 61 illus., 41 illus. in color)
ISBN
9783319145563
9783319145556 (print ed.)
Subjects (MeSH)
Arteriosclerosis
Microcirculation
Abstract
As our knowledge about arterial disease is greatly expanding, the aim of this book is to explore all aspects of arterial pathology, including classification, clinical manifestations, pathogenesis, and therapeutic options. The discussion of pathophysiologic mechanisms of arterial disease is wide ranging, encompassing hemodynamic, metabolic, humoral, inflammatory, genetic and environmental factors. Particular emphasis is placed on recent concepts, such as: the role of age-associated arterial alterations in the initiation and progression of cardiovascular diseases in older persons, the importance of mineral metabolism-bone vascular interactions, the clinical and prognostic significance of the renal resistive index, retinal circulation, toxemia of pregnancy as an arterial disease, and the role of pulmonary/vascular interaction in pulmonary hypertension and cross-talk of macrocirculation and microcirculation in target organ involvement. Evaluation procedures are carefully explained, and the full range of currently available therapeutic options, including lifestyle modifications and pharmacologic approaches, are described and appraised.
Contents
[publisher supplied] PART I. Introduction: Definition and epidemiology of arterial disease -- PART II. Normal structure and physiology of the arterial system -- PART III. Classification of arterial pathology and clinical manifestations: Atherosclerosis -- Arteriosclerosis -- Disease of Precapillary resistance vessels -- PART IV. Pathogenetic mechanisms in arterial disease: Hemodynamic and mechanical factors -- Metabolic factors -- Inflammatory markers -- Neurohormonal interactions -- Mineral-bone/ arterial interactions -- Endothelial function and impairment -- Miscellaneous: Pharmacologic/factors/environmental factors -- PART V. Systemic arterial disorders: Arterial aging -- Diabetes mellitus -- Metabolic Syndrome/obesity -- Chronic kidney disease/Renovascular interactions -- Pulmonary Hypertension/Pulmonary vascular interactions -- Systemic vasculitides -- Genetic/ degenerative disorders -- Hypertension -- Toxemia of pregnancy -- Kidney transplants, both donors and recipients -- PART VI. Evaluation procedures: Arterial function -- Renal resistive index -- Retinal microcirculation -- PART VII. Therapeutic options: Lifestyle modifications -- Pharmacologic approaches.
Format
e-Book
Location
Online
Less detail

Arterial Revascularization of the Head and Neck : Text Atlas for Prevention and Management of Stroke

https://libcat.nshealth.ca/en/permalink/provcat40259
Horia Muresian, editor. --Cham: Springer , c2016.
Available Online
View e-Book
Location
Online
This book covers all aspects of the prevention, diagnosis, and treatment of stroke, offering an integrated perspective that will be relevant to a range of specialists. Extensive consideration is given to the different methods of stroke prevention and arterial revascularization, with up-to-date information on pharmacological measures and clear presentation of endovascular stent placement procedures and surgical techniques, including those involving the carotid artery, vertebral artery, and aorti…
Available Online
View e-Book
Other Authors
Muresian, Horia
Responsibility
Horia Muresian, editor
Place of Publication
Cham
Publisher
Springer
Date of Publication
c2016
Physical Description
1 online resource (x, 368 p. : 176 illus., 128 illus. in color)
ISBN
9783319341934
9783319341910 (print ed.)
Subjects (MeSH)
Cerebral Revascularization - methods
Cerebrovascular Circulation - physiology
Head - blood supply
Neck - blood supply
Stroke - prevention & control
Abstract
This book covers all aspects of the prevention, diagnosis, and treatment of stroke, offering an integrated perspective that will be relevant to a range of specialists. Extensive consideration is given to the different methods of stroke prevention and arterial revascularization, with up-to-date information on pharmacological measures and clear presentation of endovascular stent placement procedures and surgical techniques, including those involving the carotid artery, vertebral artery, and aortic arch. Complex procedures, such as simultaneous bilateral carotid revascularization, are discussed in depth, drawing on a large series of cases and setting out practical rules. The diagnosis and treatment of intra- and extracranial aneurysms and the management of cervical trauma are examined fully. In addition, the reader is provided with guidance on characterization of the culprit lesion by means of different imaging modalities and with advice on the importance of a multidisciplinary team and combined approaches (endovascular and surgical), identification of risk factors, anesthesia, neuromonitoring, and hemodynamic monitoring. The book will be of value not only for cardiac and vascular surgeons but also for cardiologists, neurologists, neurosurgeons, anesthesiologists, anatomists, specialists in diagnostic imaging, and interventional radiologists.
Contents
The cerebral circulation -- Cerebral vascular territories and the major neurovascular syndromes -- Stroke subtypes -- Surgical approaches for cerebrovascular revascularization -- Diagnostic approach to cerebrovascular disease: ultrasound -- Endovascular approach: from diagnosis to therapy -- Diagnostic approach to cerebrovascular disease: CT and MRI -- Pharmacological measures for the treatment and prevention of stroke. The choice of initial therapy -- Anesthesia for carotid surgery and stenting. Neuromonitoring and perioperative care -- Carotid angioplasty and stenting -- Carotid endarterectomy -- Vertebral artery revascularization -- Extensive cerebrovascular arterial revascularization -- Cervico-cerebral arteries dissection -- Extracranial carotid and vertebral artery aneurysm -- Asymptomatic carotid and vertebral artery stenosis -- Lessons from experimental-induced atherosclerosis: valuable for the precision medicine of tomorrow -- Choice of the proper therapeutic measure in the individual patient and prevention of stroke.
Format
e-Book
Location
Online
Less detail

Assessment of Preclinical Organ Damage in Hypertension

https://libcat.nshealth.ca/en/permalink/provcat39219
Enrico Agabiti Rosei, Giuseppe Mancia, editors. --Cham: Springer , c2015.
Available Online
View e-Book
Location
Online
This book presents up-to-date information on how to assess early preclinical alterations in the heart, the small and large arteries and the kidney in the general and the hypertensive population, using the most sensitive, specific and cost-effective techniques. A wide variety of techniques are discussed, with careful attention to the latest developments. For each organ, evidence is documented regarding the prevalence of organ damage. Information is provided on the potential induction of regressi…
Available Online
View e-Book
Other Authors
Agabiti Rosei, Enrico
Mancia, Giuseppe
Responsibility
Enrico Agabiti Rosei, Giuseppe Mancia, editors
Place of Publication
Cham
Publisher
Springer
Date of Publication
c2015
Physical Description
1 online resource (viii, 218 p. : 44 illus., 28 illus. in color)
ISBN
9783319156033
9783319156026 (print ed.)
Subjects (MeSH)
Cardiovascular Diseases - diagnosis
Cerebrovascular Disorders - diagnosis
Diagnostic Techniques, Cardiovascular
Hypertension - complications
Hypertension - therapy
Kidney Function Tests - methods
Prodromal Symptoms
Abstract
This book presents up-to-date information on how to assess early preclinical alterations in the heart, the small and large arteries and the kidney in the general and the hypertensive population, using the most sensitive, specific and cost-effective techniques. A wide variety of techniques are discussed, with careful attention to the latest developments. For each organ, evidence is documented regarding the prevalence of organ damage. Information is provided on the potential induction of regression of organ damage by treatment, the criteria for establishing significant changes and the clinical prognostic significance of regression. The manual will be invaluable for all practitioners responsible for the clinical management of hypertensive patients, given that the assessment of early preclinical cardiovascular and renal damage permits more accurate risk stratification at baseline and facilitates evaluation of cardiovascular protection when regression of structural changes is achieved during treatment.
Contents
PART I: HEART 1 Electrocardiography -- 2 Echocardiography -- 3 New techniques: 3D, CT, MRI -- PART II: LARGE ARTERIES 4 Ultrasound of Carotid IMT and plaque -- 5 Ultrasound of the Aorta/coronary arteries -- Pulse wave velocity and central BP -- 7 Ankle-brachial index -- 8 Atherosclerosis and general principles of arterial imaging -- 9 Imaging and ageing of the aorta and large arteries in the lower extremities -- PART III: SMALL ARTERIES 10 Micro myography -- 11 Damage of the retinal arterioles -- 12 Capillaroscopy -- 13 Other techniques for assessment -- PART IV: KIDNEY 14 Proteinuria -- 15 Glomerular Filtration Rate -- 16 Other techniques -- PART V: BRAIN 17 RMN/TC: Evaluation of Brain damage -- 18 Questionnaires for cognitive function -- 19 Other techniques for neurological damage -- 20 Relation between blood pressure and markers of organ damage.
Format
e-Book
Location
Online
Less detail

Asymptomatic Atherosclerosis : Pathophysiology, Detection and Treatment

https://libcat.nshealth.ca/en/permalink/provcat28741
edited by Morteza Naghavi. --New York, NY: Humana Press , c2010.
Available Online
View e-Book
Location
Online
Despite recent advances in the diagnosis and treatment of symptomatic atherosclerosis, available traditional screening methods for early detection and treatment of asymptomatic coronary artery disease are grossly insufficient and fail to identify the majority of victims prior to the onset of a life-threatening event. In Asymptomatic Atherosclerosis: Pathophysiology, Detection and Treatment, Dr. Morteza Naghavi and leading authorities from the Society for Heart Attack Prevention and Eradication …
Available Online
View e-Book
Author
Naghavi, Morteza
Responsibility
edited by Morteza Naghavi
Place of Publication
New York, NY
Publisher
Humana Press
Date of Publication
c2010
Physical Description
1 online resource (xxii, 737 p. : ill.)
Series Title
Contemporary cardiology (Totowa, N.J. : Unnumbered)
ISBN
9781603271790
9781603271783 (print ed.)
Subjects (MeSH)
Atherosclerosis - diagnosis
Atherosclerosis - physiopathology
Atherosclerosis - therapy
Plaque, Atherosclerotic
Subjects (LCSH)
Cardiology
Abstract
Despite recent advances in the diagnosis and treatment of symptomatic atherosclerosis, available traditional screening methods for early detection and treatment of asymptomatic coronary artery disease are grossly insufficient and fail to identify the majority of victims prior to the onset of a life-threatening event. In Asymptomatic Atherosclerosis: Pathophysiology, Detection and Treatment, Dr. Morteza Naghavi and leading authorities from the Society for Heart Attack Prevention and Eradication (SHAPE) present a new paradigm for the screening and primary prevention of asymptomatic atherosclerosis. The text focuses on accurate, yet underutilized, measures of subclinical atherosclerosis, notably coronary artery calcium scanning and carotid intima-media thickness measurement. The authors introduce a comprehensive approach to identifying the vulnerable patients (asymptomatic individuals at risk of a near future adverse event). Additional chapters discuss future directions towards containing the epidemic of atherosclerotic cardiovascular disease using innovative solutions such as preemptive interventional therapies (bioabsorbable stents) for stabilization of vulnerable atherosclerotic plaques, mass unconditional Polypill therapy for population-based risk reduction, and ultimately vaccination strategies to prevent the development of atherosclerosis. Up-to-date and authoritative, Asymptomatic Atherosclerosis: Pathophysiology, Detection, and Treatment is a must-have for any cardiologist or primary care physician who wishes to practice modern preventive cardiology and manage the increasing number of asymptomatic atherosclerotic patients. Outlines more accurate measures of risk (coronary artery calcium and carotid intima-media thickness) than traditional risk factors (total cholesterol, LDL cholesterol, HDL cholesterol). Presents new multipronged strategies to aid in the early detection and treatment of high risk asymptomatic patients.
Contents
1. Preventive Cardiology: The SHAPE of the Future -- 2. From Vulnerable Plaque to Vulnerable Patient -- 3. Pathology of Vulnerability Caused by High-Risk (Vulnerable) Arteries and Plaques -- 4. Pathophysiology of Vulnerability Caused by Thrombogenic (Vulnerable) Blood -- 5. Vulnerability Caused by Arrhythmogenic Vulnerable Myocardium -- 6. Approach to Atherosclerosis as a Disease: Primary Prevention Based on the Detection and Treatment of Asymptomatic Atherosclerosis -- Section I. Risk Factors and Circulating Markers of Asymptomatic Atherosclerotic Cardiovascular Disease -- 7. History of the Evolution of Cardiovascular Risk Factors and the Predictive Value of Traditional Risk-Factor-Based Risk -- 8. Comprehensive Lipid Profiling Beyond LDL -- 9. New Blood Biomarkers of Inflammation and Atherosclerosis -- 10. Genomics and Proteomics: The Role of Contemporary Biomolecular Analysis in Advancing the Knowledge of Atherosclerotic Coronary Artery Disease -- 11. Circulating Endothelial Progenitor Cells: Mechanisms and Measurements -- 12. Family History: An Index of Genetic and Environmental Predisposition to Coronary Artery Disease -- 13. Endothelial Activation Markers in Sub-clinical Atherosclerosis: Insights from Mechanism-Based Paradigms -- Section II. Non Invasive, Non Imaging, Assessment of Asymptomatic Atherosclerotic Cardiovascular Disease -- 14. Exercise Stress Testing in Asymptomatic Individuals and Its Relation to Subclinical Atherosclerotic Cardiovascular Disease -- 15. The Ankle Brachial Index -- 16. Arterial Elasticity/Stiffness -- 17. Assessment of Endothelial Function in Clinical Practice -- 18. Digital (Fingertip) Thermal Monitoring of Vascular Function: A Novel, Noninvasive, Nonimaging Test to Improve Traditional Cardiovascular Risk Assessment and Monitoring of Response to Treatments -- 19. Assessment of Macro- and Microvascular Function and Reactivity -- Section III. Non Invasive Structural Imaging of Asymptomatic Atherosclerotic Cardiovascular Disease -- 20. Coronary Artery Calcium Imaging -- 21. Noninvasive Ultrasound Imaging of Carotid Intima Thickness -- 22. Carotid Intima-Media Thickness: Clinical Implementation in Individual Cardiovascular Risk Assessment -- 23. Computed Tomographic Angiography -- 24. Role of Noninvasive Imaging using CT for Detection and Quantitation of Coronary Atherosclerosis -- 25. Noninvasive Coronary Plaque Characterization: CT Versus MRI -- 26. Magnetic Resonance Imaging -- 27. The Role of MRI in Examining Subclinical Carotid Plaque -- 28. Comprehensive Non-contrast CT Imaging of the Vulnerable Patient -- Section IV. Non Invasive Functional Imaging of Asymptomatic Atherosclerotic Cardiovascular Disease -- 29. Ultrasound Assessment of Brachial Artery Reactivity -- 30. Cardiac Imaging for Ischemia in Asymptomatic Patients: Use of Coronary Artery Calcium Scanning to Improve Patient Selection: Lessons from the EISNER Study -- 31. Targeted MRI of Molecular Components in Atherosclerotic Plaque -- 32. Noninvasive Imaging of the Vulnerable Myocardium: Cardiac MRI and CT Based -- Section V. Invasive (Intravascular) Risk Stratification for Detection of Vulnerable (High-Risk) Asymptomatic Atherosclerotic Plaques -- 33. Angiography for Detection of Complex and Vulnerable Atherosclerotic Plaque -- 34. Intravascular Characterization of Vulnerable Coronary Plaque -- 35. Detecting Vulnerable Plaque Using Invasive Methods -- 36. Assessment of Plaque Burden and Plaque Composition Using Intravascular Ultrasound -- 37. Vulnerable Anatomy; The Role of Coronary Anatomy and Endothelial Shear Stress in the Progression and Vulnerability of Coronary Artery Lesions: Is Anatomy Destiny? -- 38. Vasa Vasorum Imaging -- Section VI. Screening for Risk Assessment of Asymptomatic At-Risk Population and Identification of the Vulnerable Patient – The SHAPE Paradigm - 39. From Vulnerable Plaque to Vulnerable Patient – Part III. -- 40. Cost Effectiveness of Screening Atherosclerosis -- 41. Monitoring of Subclinical Atherosclerotic Disease -- 42. Implications of SHAPE Guideline for Improving Patient Compliance -- 43. The SHAPE Guideline: Why Primary Care Physicians Should Embrace It -- 44. Should We Treat According to the SHAPE Guidelines? -- 45. Duty-Bound: Rational Foundations of Clinical Strategies for Prevention of Cardiovascular Events -- 46. A Time to Live: Dynamic Changes in Risk as the Basis for Therapeutic Triage -- Section VII. Treatment of Asymptomatic Atherosclerotic Cardiovascular Disease and the Vulnerable Patients: Systemic Therapies -- 47. LDL Targeted Therapies -- 48. Antioxidants as Targeted Therapy: A Special Protective Role for Pomegranate and Paraoxonases (PONs -- 49. The Multiconstituent Cardiovascular Pill (MCCP): Challenges and Promises of Population Based Prophylactic Drug Therapy for Heart Attack Prevention and Eradication -- 50. Vaccine for Atherosclerosis: An Emerging New Paradigm -- Section VIII. Local and Focal Therapies for Stabilization of Vulnerable Arteries and Plaques -- 51. Drug-Eluting Stents: A Potential Preemptive Treatment Choice for Vulnerable Coronary Plaques -- 52. Intrapericardial Approach for Pancoronary Stabilization of the Vulnerable Arteries and Myocardium -- Section IX. Educations, Life Style Modifications and Non-Pharmacologic Treatments for Primary Prevention and Saving the Vulnerable -- 53. Dietary Management for Coronary Atherosclerosis Prevention and Treatment -- 54. Management of Preconditioning Physical Activity in a Vulnerable Patient: Getting in SHAPE -- 55. Last Chance for Prevention (Acute Prevention): Identification of Prodromal Symptoms and Early Heart Attack Care.
Format
e-Book
Location
Online
Less detail
Elsevier
Available Online
View e-Journal
Holdings
v. 190, 2007 -
Location
Online
Available Online
View e-Journal
Publisher
Elsevier
Holdings
v. 190, 2007 -
ISSN
0021-9150
Format
e-Journal
Location
Online
Less detail
Elsevier
Available Online
View e-Journal
Holdings
Vol 190, 2007 -
Location
Online
Available Online
View e-Journal
Publisher
Elsevier
Holdings
Vol 190, 2007 -
Publication Frequency
Semiannual
ISSN
0021-9150
Specialty
Cardiology
Format
e-Journal
Location
Online
Less detail

Atherosclerosis and Oxidant Stress : A New Perspective

https://libcat.nshealth.ca/en/permalink/provcat29697
edited by Jordan L. Holtzman. --Boston, MA: Springer-Verlag US , c2008.
Available Online
View e-Book
Location
Online
Available Online
View e-Book
Author
Holtzman, Jordan L
Responsibility
edited by Jordan L. Holtzman
Place of Publication
Boston, MA
Publisher
Springer-Verlag US
Date of Publication
c2008
ISBN
9780387723471
Subjects (MeSH)
Atherosclerosis - etiology
Oxidative Stress - physiology
Subjects (LCSH)
Cardiology
Biochemistry
Format
e-Book
Location
Online
Less detail

Atherosclerosis : clinical perspectives through imaging

https://libcat.nshealth.ca/en/permalink/provcat32333
Allen J. Taylor, Todd C. Villines, editors. --London: Springer , c2013.
Available Online
View e-Book
Location
Online
Atherosclerosis: Clinical Perspectives Through Imaging is aimed at practicing clinicians and relies on didactic tabular and bullet points and a host of fine imagery describing the common features of the imaging of atherosclerosis, enabling the reader to understand more about the advantages and limitations of each modality in investigating athersclosis. Edited by and contributed to by a host of international experts in cardiac imaging, this book is a must read by all who image the heart.
Available Online
View e-Book
Other Authors
Taylor, Allen J
Villines, Todd C
Responsibility
Allen J. Taylor, Todd C. Villines, editors
Place of Publication
London
Publisher
Springer
Date of Publication
c2013
Physical Description
1 online resource (xiv, 228 p. : 191 ill., 110 ill. in color)
ISBN
9781447142881
Subjects (MeSH)
Atherosclerosis
Cardiology
Subjects (LCSH)
Cardiology
Abstract
Atherosclerosis: Clinical Perspectives Through Imaging is aimed at practicing clinicians and relies on didactic tabular and bullet points and a host of fine imagery describing the common features of the imaging of atherosclerosis, enabling the reader to understand more about the advantages and limitations of each modality in investigating athersclosis. Edited by and contributed to by a host of international experts in cardiac imaging, this book is a must read by all who image the heart.
Contents
Part I. Basics and Clinical Atherosclerosis -- Part II. Imaging for the Detection of Atherosclerosis -- Index.
Format
e-Book
Location
Online
Less detail

Atherosclerosis Pathogenesis and Microvascular Dysfunction

https://libcat.nshealth.ca/en/permalink/provcat44655
Axel Haverich, Erin Colleen Boyle. --Cham: Springer , c2019.
Available Online
View e-Book
Location
Online
This book provides new perspectives on the pathogenesis of atherosclerosis. Chapters cover atherosclerosis risk factors, the effect of growth and aging on vascular architecture, and the crucial role the microvasculature plays in atherosclerosis development. Microvascular dysfunction would explain why the well-known risk factors actually put individuals at higher risk. This pathomechanism would also hold true not only for obstructive atheroma formation but also for aneurysmal dilatation as well …
Available Online
View e-Book
Author
Haverich, Axel
Other Authors
Boyle, Erin Colleen
Responsibility
Axel Haverich, Erin Colleen Boyle
Place of Publication
Cham
Publisher
Springer
Date of Publication
c2019
Physical Description
1 online resource (x, 130 p.) : 18 illus., 15 illus. in color
ISBN
9783030202453
9783030202446 (Print ed.)
9783030202460 (Print ed.)
9783030202477 (Print ed.)
Subjects (MeSH)
Atherosclerosis - physiopathology
Microvessels - physiopathology
Specialty
Cardiology
Pathology
Abstract
This book provides new perspectives on the pathogenesis of atherosclerosis. Chapters cover atherosclerosis risk factors, the effect of growth and aging on vascular architecture, and the crucial role the microvasculature plays in atherosclerosis development. Microvascular dysfunction would explain why the well-known risk factors actually put individuals at higher risk. This pathomechanism would also hold true not only for obstructive atheroma formation but also for aneurysmal dilatation as well as for aortic and peripheral artery dissection. When seen through this lens, novel preventive and therapeutic opportunities can be envisioned. Atherosclerosis Pathogenesis and Microvascular Dysfunction proposes a single unifying mechanism of atherosclerosis development and describes potential preventative and therapeutic avenues based on this concept. It therefore represents a timely and valuable resource for internal medicine, cardiology, angiology cardiovascular surgeons, pathology clinicians, researchers, trainees, and students.
Contents
Introduction -- Atherosclerosis Risk Factors -- The Effect Of Growth And Aging On Vascular Architecture -- Incriminating Evidence For The Role Of The Microvasculature In Atherosclerosis -- Risk Factors And Prevention In Light Of Atherosclerosis Being A Microvascular Disease -- New Ways To Target Vasa Vasorum For The Prevention And Treatment Of Atherosclerosis -- Supporting Microvasculature Function.
Format
e-Book
Location
Online
Less detail

Atherosclerosis plus

https://libcat.nshealth.ca/en/permalink/provcat47183
Elsevier
Available Online
View e-Journal
Holdings
Vol 43, 2021 -
Location
Online
Available Online
View e-Journal
Publisher
Elsevier
Holdings
Vol 43, 2021 -
ISSN
2667-0895
Specialty
Cardiology
Format
e-Journal
Location
Online
Less detail

Atherosclerosis plus

https://libcat.nshealth.ca/en/permalink/provcat51462
Elsevier B.V.
Available Online
View e-Journal
Holdings
v. 43, 2021 -
Location
Online
Available Online
View e-Journal
Publisher
Elsevier B.V.
Holdings
v. 43, 2021 -
ISSN
2667-0895
Format
e-Journal
Location
Online
Less detail

Atlas of Atherosclerosis and Metabolic Syndrome

https://libcat.nshealth.ca/en/permalink/provcat28933
edited by Scott M. Grundy. (5th ed.) --New York, NY: Springer Science+Business Media , c2011.
Available Online
View e-Book
Location
Online
Available Online
View e-Book
Author
Grundy, Scott M
Responsibility
edited by Scott M. Grundy
Edition
5th ed.
Place of Publication
New York, NY
Publisher
Springer Science+Business Media
Date of Publication
c2011
ISBN
9781441958396
Subjects (MeSH)
Atherosclerosis - pathology - Atlases
Metabolic Syndrome X - pathology - Atlases
Lipoproteins - metabolism
Subjects (LCSH)
Cardiology
Metabolic diseases
Format
e-Book
Location
Online
Less detail

Atlas of Coronary Intravascular Optical Coherence Tomography

https://libcat.nshealth.ca/en/permalink/provcat43263
Annapoorna Kini, Jagat Narula, Yuliya Vengrenyuk, Samin Sharma. --Cham: Springer , c2018.
Available Online
View e-Book
Location
Online
This atlas is a practical and fully illustrated guide to the use of intravascular OCT in diagnosis and treatment of coronary artery disease. It consists of two parts. The first part of the book provides a systematic introduction to coronary imaging with OCT. It describes how to interpret images and describes abnormal findings seen in atherosclerosis, complications after intervention, and stent assessment. The second part of the book presents real-life case studies that show how OCT is used in c…
Available Online
View e-Book
Author
Kini, Annapoorna
Other Authors
Narula, Jagat
Vengrenyuk, Yuliya
Sharma, Samin
Responsibility
Annapoorna Kini, Jagat Narula, Yuliya Vengrenyuk, Samin Sharma
Place of Publication
Cham
Publisher
Springer
Date of Publication
c2018
Physical Description
1 online resource (xiii, 100 p.) : 81 illus. in color
ISBN
9783319626666
9783319626642 (print ed.)
9783319626659 (print ed.)
9783319873664 (print ed.)
Subjects (MeSH)
Coronary Vessels - diagnostic imaging
Tomography, Optical Coherence
Specialty
Cardiology
Diagnostic Imaging
Abstract
This atlas is a practical and fully illustrated guide to the use of intravascular OCT in diagnosis and treatment of coronary artery disease. It consists of two parts. The first part of the book provides a systematic introduction to coronary imaging with OCT. It describes how to interpret images and describes abnormal findings seen in atherosclerosis, complications after intervention, and stent assessment. The second part of the book presents real-life case studies that show how OCT is used in clinical practice in Mount Sinai to assess the disease, select appropriate treatment, and evaluate complications and results. Each case includes a brief clinical history, procedure summary, angiography and OCT images, including video material, and a discussion of how OCT affected the clinical decision-making process.
Contents
1. Optical Coherence Tomography: Principles, Image Acquisition, and Assessment -- 2. Acute Coronary Syndrome: Ruptured and Intact Fibrous Caps -- 3. Stable Coronary Artery Disease: Assistance in Complex Percutaneous Coronary Intervention -- 4. Post-Stent Evaluation, Stent Thrombosis, and In-Stent Restenosis -- 5. New Stents, New Procedures, and Intraprocedural Challenges.
Format
e-Book
Publication Type
Atlas
Case Reports
Location
Online
Less detail

Atlas of nuclear cardiology

https://libcat.nshealth.ca/en/permalink/provcat32432
Vasken Dilsizian, Jagat Narula, editors. (4th ed.) --New York, NY: Springer , c2013.
Available Online
View e-Book
Location
Online
The newly updated and expanded Atlas of Nuclear Cardiology, Fourth Edition provides physicians and trainees with the most up-to-date information in a rapidly changing field. In addition to beautifully rendered color illustrations, the atlas emphasizes key points with a multitude of diagnostic algorithms and schematic diagrams integrated with nuclear cardiology procedures. Relevant for the clinical practice of nuclear cardiology, each chapter focuses on material of practical merit. The book give…
Available Online
View e-Book
Other Authors
Dilsizian, Vasken
Narula, Jagat
Responsibility
Vasken Dilsizian, Jagat Narula, editors
Edition
4th ed.
Place of Publication
New York, NY
Publisher
Springer
Date of Publication
c2013
Physical Description
1 online resource (x, 457 p. : 439 ill., 415 ill. in color)
ISBN
9781461455516
Subjects (MeSH)
Cardiovascular Diseases - diagnostic imaging
Heart - diagnostic imaging - Atlases
Radionuclide Imaging
Subjects (LCSH)
Radiology, Medical
Nuclear medicine
Cardiology
Abstract
The newly updated and expanded Atlas of Nuclear Cardiology, Fourth Edition provides physicians and trainees with the most up-to-date information in a rapidly changing field. In addition to beautifully rendered color illustrations, the atlas emphasizes key points with a multitude of diagnostic algorithms and schematic diagrams integrated with nuclear cardiology procedures. Relevant for the clinical practice of nuclear cardiology, each chapter focuses on material of practical merit. The book gives full coverage to areas of cardiac physiology, pathology, and metabolism. The utility of noninvasive cardiovascular nuclear imaging techniques for diagnosis, screening and evaluation is discussed in the context of various clinical scenarios, including heart failure, acute coronary syndrome, and atherosclerosis. Written by an expert group of researchers and clinicians, the atlas emphasizes today's most current information, providing a invaluable resource and meeting the requirements for those who will be using the book as a reference source for certifying or re-certifying in cardiology, nuclear cardiology, nuclear medicine or radiology.
Contents
Principles of nuclear cardiology imaging -- SPECT and PET myocardial perfusion imaging: tracers and techniques -- Hybrid SPECT/CT and PET/CT imaging -- Physiologic and pharmacologic stressors -- Quantitation of myocardial perfusion: absolute blood flow versus relative uptake -- Assessment of cardiac function: first-pass, equilibrium blood pool, and gated myocardial SPECT -- Risk stratification and patient management -- Imaging cardiac metabolism -- Nuclear investigation in heart failure and myocardial viability -- Diagnosis and risk stratification in acute coronary syndromes -- Myocardial innervation -- Integrated structural-molecular imaging of atherosclerosis -- Index.
Format
e-Book
Location
Online
Less detail

Behçet's syndrome : from pathogenesis to treatment

https://libcat.nshealth.ca/en/permalink/provcat33798
Lorenzo Emmi, editor. --Milan: Springer , c2014.
Available Online
View e-Book
Location
Online
Behçet's syndrome can reasonably be considered a unique entity among diseases of the immune system for several reasons: It has specific features and, uniquely among the immune system pathologies, represents a link between autoimmune diseases, systemic vasculitis, and autoinflammatory diseases. In addition, it is of interest to a variety of specialists, including immunologists, rheumatologists, dermatologists, and ophthalmologists, and requires a complex multidisciplinary approach. Many aspects …
Available Online
View e-Book
Other Authors
Emmi, Lorenzo
Responsibility
Lorenzo Emmi, editor
Alternate Title
Behcet's syndrome
Place of Publication
Milan
Publisher
Springer
Date of Publication
c2014
Physical Description
1 online resource (x, 229 pages)
Series Title
Rare diseases of the immune system
ISBN
9788847054776 (electronic bk.)
9788847054769
Subjects (MeSH)
Behcet Syndrome - etiology
Behcet Syndrome - therapy
Subjects (LCSH)
Behçet's disease
Rare diseases
Behcet Syndrome
Abstract
Behçet's syndrome can reasonably be considered a unique entity among diseases of the immune system for several reasons: It has specific features and, uniquely among the immune system pathologies, represents a link between autoimmune diseases, systemic vasculitis, and autoinflammatory diseases. In addition, it is of interest to a variety of specialists, including immunologists, rheumatologists, dermatologists, and ophthalmologists, and requires a complex multidisciplinary approach. Many aspects need to be considered in a syndrome that presents a wide spectrum of symptoms and for which the therapeutic armamentarium is expanding significantly, with the development of new treatments, not least the so-called biologics. This book offers comprehensive coverage of the disease by some of the world's leading experts in Behçet's syndrome from all the relevant specialties. Epidemiology, genetics, pathogenesis, organ system involvement, differential diagnosis, novel treatments, surgical management, and prognosis are just some of the topics addressed. Behçet's Syndrome: From Pathogenesis to Treatment will be an invaluable reference for a range of practitioners, researchers, and undergraduates or postgraduates interested in immunorheumatology, dermatology, and rare diseases.
Contents
1. The Numbers of Behçet: A Rare Disease? -- 2. From Hippocrates to Hulusi Behçet: What History -- 3. Epidemiology of Behçet Syndrome -- 4. Behçet’s Syndrome According to Classical and Population Genetics -- 5. Infections, Autoimmunity, and Behçet’s Syndrome: What Liaison? -- 6. Pathogenesis of Behçet Syndrome -- 7. Mucocutaneous Involvement in Behçet’s Syndrome -- 8. Neurological and Neuropsychological Manifestation in Behçet’s Syndrome -- 9. Ocular Involvement and Behçet Disease -- 10. Articular and Muscular Manifestations in Behçet’s Disease -- 11. Cardiovascular Issues: Aneurysms and Pseudoaneurysms, Thrombosis, Atherosclerosis, and Cardiac Involvement -- 12. Intestinal Behçet Disease -- 13. Audio Vestibular Involvement in Behçet’s Disease -- 14. Behçet’s Syndrome and Gynecological Manifestation in Reproductive Age and Pregnancy -- 15. Pediatric Onset of Behçet Syndrome -- 16. Behçet’s Disease. Differential Diagnosis -- 17. Classification and Diagnosis Criteria for Behçet’s Disease -- 18. Prognosis and Disease Activity -- 19. Old and New Treatment for Behçet’s Disease -- 20. Surgical Treatment of Angio-Behçet.
Format
e-Book
Location
Online
Less detail

The biology of human longevity : inflammation, nutrition, and aging in the evolution of lifespans

https://libcat.nshealth.ca/en/permalink/provcat27590
Finch, Caleb E. --Amsterdam, Netherlands: Elsevier Academic Press , 2007.
Available Online
View e-Book
Location
Online
Available Online
View e-Book
Author
Finch, Caleb E
Place of Publication
Amsterdam, Netherlands
Publisher
Elsevier Academic Press
Date of Publication
2007
Physical Description
626 p.
ISBN
9780080545943
Subjects (MeSH)
Longevity - physiology
Aging - physiology
Inflammation
Nutritional Physiological Phenomena
Contents
1. INFLAMMATION AND OXIDATION IN AGING AND CHRONIC DISEASES. 1.1. Overview ; 1.2. Experimental models for aging ; 1.3. Outline of inflammation ; 1.4. Bystander damage and dependent variables in senescence ; 1.5 Arterial aging and atherosclerosis ; 1.6. Alzheimer disease and vascular-related dementias ; 1.7. Inflammation in obesity ; 1.8. Processes of normal aging in the absence of specific diseases ; 1.9. Summary -- 2. INFECTIONS, INFLAMMOGENS, AND DRUGS. 2.1. Introduction ; 2.2. Vascular disease ; 2.3. Infections from the central tube : Metchnikoff revisited ; 2.4. Aerosols and dietary inflammogens ; 2.5. Infections, inflammation, and life span ; 2.6. Are infections a cause of obesity? ; 2.7. Inflammation, dementia, and cognitive decline ; 2.8. Immunosenescence and stem cells ; 2.9. Cancer, infection, and inflammation ; 2.10. Pharmacopleiotropies in vascular disease, dementia, and cancer ; 2.11. Summary -- 3. ENERGY BALANCE, INFLAMMATION, AND AGING. 3.1. Introduction ; 3.2. Diet restriction and aging ; 3.3. Energy sensing in diet restriction and satiety ; 3.4. Exercise, cardiovascular health, and longevity ; 3.5. Diet, exercise, and neurodegeneration ; 3.6. Laboratory rodents as models for the 'couch potato' ; 3.7. Energy balance in the life history ; 3.8. Summary -- 4. NUTRITION AND INFECTION IN THE DEVELOPMENTAL INFLUENCES ON AGING. 4.1. Introduction ; 4.2. Synopsis of the fetal origins theory ; 4.3. The Barker studies of infections and vascular disease ; 4.4. Size, health, and longevity ; 4.5. Infection and undernutrition on birthweight and later disease ; 4.6. Infection and nutrition in postnatal development and later disease ; 4.7. Famine ; 4.8. Maternal physiology, fetal growth, and later chronic disease ; 4.9. Growth in adaptive responses to the environment ; 4.10. Genomics of fetal growth regulation ; 4.11. Summary -- 5. GENETICS. 5.1. Introduction ; 5.2. Sources of individual variations in aging and life span ; 5.3. Sex differences in longevity ; 5.4. Metabolism and host-defense in worm and fly ; 5.5. The worm ; 5.6. Fly ; 5.7. Mammals ; 5.8. Summary -- 6. THE HUMAN LIFE SPAN : PRESENT, PAST, AND FUTURE. 6.1. Introduction ; 6.2. From great ape to human ; 6.3. Four major shifts in human life history from genetic and cultural evolution ; 6.4. The instability of life spans ; 6.5. Summary of chapters 1-6 : mechanisms in aging and life history evolution.
Format
e-Book
Location
Online
Less detail

Cardiac valvular medicine

https://libcat.nshealth.ca/en/permalink/provcat32326
Nalini M. Rajamannan, editor. --Dordrecht: Springer , c2013.
Available Online
View e-Book
Location
Online
Experimental studies in the field of cardiac valve biology are now demonstrating that the cardiac valve disease process is an active biology with risk factors analogous to vascular risk factors. Understanding the risk factors is also evolving rapidly, giving physicians and scientists insight into the cellular mechanisms and raising the possibility of treating these valve lesions with other options besides surgical valve repair. Our knowledge of right-sided valve lesions is also rapidly becoming…
Available Online
View e-Book
Other Authors
Rajamannan, Nalini M
Responsibility
Nalini M. Rajamannan, editor
Place of Publication
Dordrecht
Publisher
Springer
Date of Publication
c2013
Physical Description
1 online resource (xiii, 254 p. : 114 ill., 97 ill. in color)
ISBN
9781447141327
Subjects (MeSH)
Heart Valve Diseases
Subjects (LCSH)
Internal medicine
Cardiology
Heart - Surgery
Abstract
Experimental studies in the field of cardiac valve biology are now demonstrating that the cardiac valve disease process is an active biology with risk factors analogous to vascular risk factors. Understanding the risk factors is also evolving rapidly, giving physicians and scientists insight into the cellular mechanisms and raising the possibility of treating these valve lesions with other options besides surgical valve repair. Our knowledge of right-sided valve lesions is also rapidly becoming important in the field of valvular medicine. Not only is the pathology different from left-sided valve lesions, but the hemodynamic compromise is more complex and difficult to treat in patients who develop tricuspid or pulmonic valve disease. Early diagnosis and careful management of this patient population is critical for long term outcomes in this patient population. Cardiac Valvular Medicine represents an overview of the most recent science, clinical trials and new discoveries in the field of valvular heart disease. The editor has assembled a team of highly experienced contributors to provide a thorough translational understanding of the current and future treatments for this patient population. Cardiologists, internists, family practice physicians, cardiac surgeons and basic scientists will all find enormous benefit from this textbook.
Contents
1. Modifying the Natural History of Aortic Valve Stenosis -- 2. Cardiovascular Risk Factors for Calcific Aortic Valve Disease -- 3. Bicuspid Aortic Valve Disease: From Bench to Bedside -- 4. Experimental Evidence for the Role of Atherosclerosis in Calcific Aortic Valve Disease -- 5. The Electrocardiogram as a Risk Predictor in Asymptomatic Aortic Stenosis -- 6. Exercise Testing in Aortic Stenosis and in Mitral Regurgitation -- 7. Detection of Calcium in the Aortic Valve by Non- Invasive Imaging -- 8. Assessment of Aortic Stenosis Severity:Determining Timing to Surgery -- 9. Balloon Aortic Valvuloplasty -- 10. Imaging for TAVI -- 11. Transcutaneous Aortic Valve Implantation -- 12. Role of statins in valvular heart disease: Rheumatic valve disease and bioprosthetic valves -- 13. Slowing the Progression of Aortic Stenosis The Emerging Role of Bisphosphonates -- 14. LDL-Density-Theory:Implications for Future Clinical Trials -- 15. Infective Endocarditis: New Recommendations and Perspectives -- 16. Assessment and Timing to Intervention of Mitral Regurgitation -- 17. Biology of Mitral Valve Disease -- 18. Mitral Valve Devices -- 19. Anatomy and Pathology of Right-sided atrioventricular and semilunal valves -- 20. Mechanisms, Evaluation and Management of Tricuspid Regurgitation -- Index.
Format
e-Book
Location
Online
Less detail

Cardiorespiratory Fitness in Cardiometabolic Diseases : Prevention and Management in Clinical Practice

https://libcat.nshealth.ca/en/permalink/provcat44271
Peter Kokkinos, Puneet Narayan, editors. --Cham: Springer , 2019.
Available Online
View e-Book
Location
Online
This book examines the links between physical activity (PA), cardiorespiratory fitness (CRF), and cardiovascular and metabolic diseases. It presents an overview of the role of PA and CRF in the prevention and management of risk factors associated with cardiometabolic diseases such as hypertension, peripheral vascular disease, stroke, type 2 diabetes, metabolic syndrome, dyslipidemia, obesity, and atherosclerosis. In addition, it explores how these risks vary with different populations such as t…
Available Online
View e-Book
Other Authors
Kokkinos, Peter
Narayan, Puneet
Responsibility
Peter Kokkinos, Puneet Narayan, editors
Place of Publication
Cham
Publisher
Springer
Date of Publication
2019
Physical Description
1 online resource (xiii, 443 p.) : 56 illus., 25 illus. in color
ISBN
9783030048167
9783030048150 (Print ed.)
9783030048174 (Print ed.)
Subjects (MeSH)
Cardiovascular Diseases - prevention & control
Cardiovascular System - physiology
Exercise - physiology
Metabolic Diseases - prevention & control
Physical Exertion - physiology
Physical Fitness - physiology
Respiratory System - physiology
Risk Factors
Stress, Physiological - physiology
Specialty
Cardiology
Physical Fitness
Abstract
This book examines the links between physical activity (PA), cardiorespiratory fitness (CRF), and cardiovascular and metabolic diseases. It presents an overview of the role of PA and CRF in the prevention and management of risk factors associated with cardiometabolic diseases such as hypertension, peripheral vascular disease, stroke, type 2 diabetes, metabolic syndrome, dyslipidemia, obesity, and atherosclerosis. In addition, it explores how these risks vary with different populations such as the elderly and people of various racial backgrounds. The book also highlights risks associated with exercise and presents a prescription for appropriate and efficacious exercise to minimize risk and maximize health benefits for the heart. Cardiorespiratory Fitness in Prevention and Management of Cardiometabolic Disease is an essential resource for physicians, exercise physiologists, medical students, residents, fellows, nurses, and researchers in cardiology, cardiorespiratory fitness, exercise science, health promotion and disease prevention, public health, and epidemiology.
Contents
1. Physical Activity, Cardiorespiratory Fitness, and Health: A Historical Perspective -- 2. Exercise, Gene Regulation, and Cardiometabolic Disease -- 3. Exercise and the Mitochondria -- 4. Effect of Exercise on Adult Stem Cells -- 5. Exercise Metabolism in Health and Disease -- 6. Exercise and the Endothelium -- 7. Exertion-Related Acute Cardiovascular Events: Pathophysiologic Considerations, Risk Modulators, and Prophylactic Interventions -- 8. Exercise and Blood Pressure Control in Hypertension -- 9. Role of Physical Activity, Exercise, and Cardiorespiratory Fitness in the Management of Resistant Hypertension -- 10. Physical Activity, Blood Pressure, and Cardiac Structure and Function -- 11. Physical Activity, Cardiorespiratory Fitness, and the Diabetes Spectrum -- 12. Cardiorespiratory Fitness, Physical Activity, and Metabolic Syndrome -- 13. Exercise Interventions in Patients with Diabetes and Peripheral Artery Disease -- 14. Physical Activity, Cardiorespiratory Fitness, and Obesity -- 15. The Obesity Paradox and Cardiorespiratory Fitness -- 16. Physical Activity, Exercise, and Lipids and Lipoproteins -- 17. Physical Activity, Fitness, and Coronary Heart Disease -- 18. Physical Activity and Cardiorespiratory Fitness in Heart Failure -- 19. Cardiorespiratory Fitness, Physical Activity, and Stroke -- 20. Cardiorespiratory Fitness, Physical Activity, and Incidence of Atrial Fibrillation -- 21. Chronic Kidney Disease and Physical Activity -- 22. Physical Activity, Fitness, and Sexual Dysfunction -- 23. Cardiorespiratory Fitness in the Context of Cardiac Rehabilitation -- 24. Physical Activity and Cardiometabolic Health Benefits in Children -- 25. Association Between Cardiorespiratory Fitness and Healthcare Costs.
Format
e-Book
Location
Online
Less detail

Cardiovascular Biomechanics

https://libcat.nshealth.ca/en/permalink/provcat41566
Peter R. Hoskins, Patricia V. Lawford, Barry J. Doyle, editors. --Cham: Springer , 2017.
Available Online
View e-Book
Location
Online
This book provides a balanced presentation of the fundamental principles of cardiovascular biomechanics research, as well as its valuable clinical applications. Pursuing an integrated approach at the interface of the life sciences, physics and engineering, it also includes extensive images to explain the concepts discussed. Cardiovascular biomechanics encompasses the relationship between the mechanics of the cardiovascular system and biological function in health and disease, and it is increasi…
Available Online
View e-Book
Other Authors
Hoskins, Peter R
Lawford, Patricia V
Doyle, Barry J
Responsibility
Peter R. Hoskins, Patricia V. Lawford, Barry J. Doyle, editors
Place of Publication
Cham
Publisher
Springer
Date of Publication
2017
Physical Description
1 online resource (ix, 462 pages) : 220 illus. in color
ISBN
9783319464077
9783319464053 (print ed.)
Subjects (MeSH)
Biomechanical Phenomena
Cardiovascular Physiological Phenomena
Cardiovascular System
Abstract
This book provides a balanced presentation of the fundamental principles of cardiovascular biomechanics research, as well as its valuable clinical applications. Pursuing an integrated approach at the interface of the life sciences, physics and engineering, it also includes extensive images to explain the concepts discussed. Cardiovascular biomechanics encompasses the relationship between the mechanics of the cardiovascular system and biological function in health and disease, and it is increasingly recognised that normal function and diseases involve a complex interplay between biology and mechanical forces. With a focus on explaining the underlying principles, this book examines the physiology and mechanics of circulation, mechanobiology and the biomechanics of different components of the cardiovascular system, in-vivo techniques, in-vitro techniques, and the medical applications of this research. Written for undergraduate and postgraduate students and including sample problems at the end of each chapter, this interdisciplinary text provides an essential introduction to the topic. It is also an ideal reference text for researchers and clinical practitioners, and will benefit a wide range of students and researchers including engineers, physicists, biologists and clinicians who are interested in the area of cardiovascular biomechanics.
Contents
1. Introduction to Solid and Fluid Mechanics -- 2. Introduction to Cardiovascular Biomechanics -- 3. Blood and Blood Flow -- 4. The Arterial System I. Pressure, Flow and Stiffness -- 5. The Arterial System II. Forces, Adaptability and Mechanotransduction -- 6. Excitation-Contraction in the Heart -- 7. The Venous System -- 8. The Microcirculation -- 9. Medical Imaging -- 10. Modelling of the Cardiovascular System -- 11. Patient Specific Modelling -- 12. Flow Phantoms -- 13. Measurement of the Mechanical Properties of Biological Tissues -- 14. Hypertension -- 15. Atherosclerosis -- 16. Aneurysms -- 17. Cardiovascular Prostheses -- Appendix A: Questions -- Appendix B: Glossary.
Format
e-Book
Location
Online
Less detail

102 records – page 1 of 6.