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Gene expression profiling by microarrays : clinical implications

https://libcat.nshealth.ca/en/permalink/provcat27262
edited by Wolf-Karsten Hofmann. --Cambridge, UK: Cambridge University Press , 2006.
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Author
Hofmann, Wolf-Karsten
Responsibility
edited by Wolf-Karsten Hofmann
Place of Publication
Cambridge, UK
Publisher
Cambridge University Press
Date of Publication
2006
Physical Description
xiv, 246 p.
ISBN
6610480400 (electronic bk.)
Subjects (MeSH)
Gene expression profiling - methods
Oligonucleotide Array Sequence Analysis
Contents
Cover -- Half-title -- Title -- Copyright -- Dedication -- Contents -- Contributors -- Editor -- Foreword -- Contributors -- Foreword -- Introduction -- 1 Technique of microarrays: microarray platforms -- Introduction -- Microarray platforms -- cDNA microarrays -- Oligonucleotide microarrays -- Novel microarray platforms -- Target-labeling -- Microarray image analysis -- Accuracy and reliability of microarray platforms -- Outlook -- References -- 2 Quantitative quality control of microarray experiments: toward accurate gene expression measurements -- Introduction -- Accurate information acquisition from microarrays -- Quantitative data filtering and normalization, advantages of the quality score approach -- Quality measures from cyanine images -- Quality measures from the TD image -- R-Q LOWESS normalization and its efficiency -- Qf-weighted mean and t-test -- The accuracy of gene expression measurements by microarrays -- Discussion and conclusions -- Acknowledgments -- References -- 3 Statistical analysis of gene expression data -- Abstract -- Introduction -- Statistical background and challenges with microarray data -- Data processing -- Data acquisition and computation expression indices -- Spotted arrays -- Affymetrix arrays -- Quality control (QC) -- Gene filtering: identifying differentially expressed genes -- Observational filtering metrics -- Statistical filtering metrics -- Correction for multiple testing/false discovery rate -- Significance analysis of microarrays (SAM) -- Clustering/data visualization: unsupervised learning -- Hierarchical clustering -- Self-organizing maps (SOM) -- Principal components (PCA) -- Additional clustering techniques -- Classification/prediction: supervised learning -- Prediction models -- Model assessment and validation -- Experimental design -- Spotted array design -- Sample allocation -- Sample size -- References -- 4 Genomic stratification in patients with heart failure -- Introduction -- Animal models of HF -- Hypertrophy and HF -- Akt and apoptosis -- Tumor necrosis factor-Alpha (TNF-Alpha) -- Alpha1b-adrenergic receptor (Alpha1b-AR) -- Atrial natriuretic peptide (ANP) ablation -- Development, progression and rescue of HF in animal models -- Myocardial infarction -- Pressure overload -- Pharmacologic induction of heart failure -- Animal models of cardiac conductance abnormality -- A mouse heart gene expression database -- Cardiac development and the fetal gene program of HF -- Human HF -- Left ventricular assist devices in human HF -- Final common pathway? -- Peripheral blood mononuclear cell profiling in HF -- Conclusions -- References -- 5 Gene expression profiling for the diagnosis of acute leukemias -- Introduction -- Characterization of acute myeloid leukemia by microarray analyses -- Class prediction in AML -- Approaching class discovery in AML -- Comparison of protein expression and gene expression levels as assessed by flow cytometry and microarrays -- Prognostic studies in AML based on genetic profi
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e-Book
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Atrial Fibrillation : From Bench to Bedside

https://libcat.nshealth.ca/en/permalink/provcat30398
edited by Andrea Natale, José Jalife. --Totowa, NJ: Humana Press , c2008.
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Online
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Author
Natale, Andrea
Other Authors
Jalife, José
Responsibility
edited by Andrea Natale, José Jalife
Place of Publication
Totowa, NJ
Publisher
Humana Press
Date of Publication
c2008
Series Title
Contemporary cardiology (Totowa, N.J. : Unnumbered)
ISBN
9781597451635
Subjects (MeSH)
Atrial Fibrillation - diagnosis
Atrial Fibrillation - physiopathology
Atrial Fibrillation - therapy
Catheter Ablation - methods
Subjects (LCSH)
Cardiology
Heart - Surgery
Format
e-Book
Location
Online
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Pediatric Heart Sounds

https://libcat.nshealth.ca/en/permalink/provcat40640
by Michael E. McConnell ; with contributions by Alan Branigan. --London: Springer , c2008.
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There is, even now, no other basic physical examination skill is more important than cardiac auscultation. When a patient presents with a soft systolic murmur on auscultation, only good physical examination skills will allow the examiner to reassure the patient that the murmur is non-pathologic. This book is not an exhaustive "encyclopedia" listing every possible abnormal sound with the appropriate clinical response. Instead, the goal is to increase the reader's confidence using the stethoscope…
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Author
McConnell, Michael E
Other Authors
Branigan, Alan
Responsibility
by Michael E. McConnell ; with contributions by Alan Branigan
Place of Publication
London
Publisher
Springer
Date of Publication
c2008
Physical Description
1 online resource (xiii, 109 p. : 27 illus., 23 illus. in color)
ISBN
9781846286841
9781846286834 (print ed.)
Subjects (MeSH)
Heart Auscultation
Heart Murmurs - diagnosis
Heart Sounds
Abstract
There is, even now, no other basic physical examination skill is more important than cardiac auscultation. When a patient presents with a soft systolic murmur on auscultation, only good physical examination skills will allow the examiner to reassure the patient that the murmur is non-pathologic. This book is not an exhaustive "encyclopedia" listing every possible abnormal sound with the appropriate clinical response. Instead, the goal is to increase the reader's confidence using the stethoscope in an organized fashion, and once they have the organized system of auscultation, to improve their ability to tell pathologic from normal heart sounds.
Contents
Normal Heart Sounds -- Innocent Heart Murmurs -- Atrial Septal Defects -- Ventricular Septal Defects -- Patent Arterial Duct -- Aortic Stenosis -- Pulmonary Stenosis -- Mitral Valve Insufficiency -- Tetralogy of Fallot.
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e-Book
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Online
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ECG interpretation : the self-assessment approach

https://libcat.nshealth.ca/en/permalink/provcat27311
Zainul Abedin, Robert Conner. (2nd ed.) --Malden, MA: Blackwell Futura , 2008.
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Author
Abedin, Zainul
Other Authors
Conner, Robert P
Responsibility
Zainul Abedin, Robert Conner
Edition
2nd ed.
Place of Publication
Malden, MA
Publisher
Blackwell Futura
Date of Publication
2008
Physical Description
233 p.
ISBN
9780470765746
Subjects (MeSH)
Electrocardiography - Programmed Instruction
Arrhythmias, Cardiac - diagnosis - Programmed Instruction
Notes
"First published as: 12Lead ECG interpretation, W.B. Saunders Company, 1989"--T.p. verso
Contents
Complexes and intervals -- Mean QRS axis determination -- The normal electrocardiogram -- Intraventricular conduction defects -- Myocardial ischemia and infarction -- Chamber enlargement and hypertrophy -- Acute pericarditis -- Sinus rhythm and its discontents -- Atrioventricular block -- Atrial arrhythmias -- Supraventricular re-entrant tachycardias -- Wolff-Parkinson-White syndrome -- Junctional arrhythmias -- Ventricular arrhythmias -- Channelopathies -- Electronic pacing
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e-Book
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Management of complex cardiovascular problems : the evidence-based medicine approach

https://libcat.nshealth.ca/en/permalink/provcat27683
Nguyen, Thach N. --Hoboken, NJ: John Wiley & Sons , 2008.
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Author
Nguyen, Thach N.
Other Authors
Hu, Dayi
Place of Publication
Hoboken, NJ
Publisher
John Wiley & Sons
Date of Publication
2008
ISBN
9780470750858
Subjects (MeSH)
Cardiovascular Diseases - therapy
Contents
Hyperlipidemia / Vien T. Truong [and 5 others] -- Hypertension / Udho Thadani, Nguyen Duc Cong -- Stable coronary artery disease / Mohammed Haris Umer Usman [and 5 others] -- Acute coronary syndrome / Udho Thadani, Quang Tuan Nguyen, Han Yaling -- ST segment elevation myocardial infarction / Runlin Gao [and 7 others] -- Heart failure / Dan D. Le [and 5 others] -- Decompensated heart failure / Patrick Campbell [and 5 others] -- Atrial fibrillation / Mihail Chelu [and 7 others] -- Ventricular tachycardia / Sorin Lazar [and 5 others] -- Syncope / Rajasekhar Nekkanti [and 5 others] -- Aortic stenosis / Rajiv Goswami, Phillip Tran, Nguyen Lan Hieu, Aravinda Nanjundappa, Neal Kleiman -- Mitral regurgitation / Raj Nekkanti [and 6 others] -- Cardiovascular problems in the older patients / Daniel Forman, Nanette Wenger -- Cardiovascular problems in women / Kahroba Jahan, Nisa Arshad, Nguyen Phuc Nguyen, Ainol Shareha Sahar, Amsa Arshad, Kwan Lee.
Format
e-Book
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Comprehensive Cardiovascular Medicine in the Primary Care Setting

https://libcat.nshealth.ca/en/permalink/provcat28781
edited by Peter P. Toth, Christopher P. Cannon. --New York, NY: Humana Press , c2010.
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Online
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Author
Toth, Peter P
Other Authors
Cannon, Christopher P
Responsibility
edited by Peter P. Toth, Christopher P. Cannon
Place of Publication
New York, NY
Publisher
Humana Press
Date of Publication
c2010
Physical Description
1 online resource (xiii, 603 p. : ill.)
Series Title
Contemporary cardiology (Totowa, N.J. : Unnumbered)
ISBN
9781603279635
9781603279628 (print ed.)
Subjects (MeSH)
Primary Health Care
Subjects (LCSH)
Cardiology
Primary health care
Contents
Part I. Cardiovascular Disease Risk Factors -- 1. Cardiovascular Epidemiology and Characterization of Atherosclerotic Disease Risk Factors -- 2. Atrial Hypertension -- 3. Management Dyslipidemia -- 4. Obesity and Therapeutic Approaches to Weight Loss -- 5. Inflammatory Markers and Novel Risk Factors -- 6. Deciphering Cardiovascular Genomics and How They Apply to Cardiovascular Disease Prevention -- 7. The Metabolic Syndrome: 2009 -- 8. Chronic Kidney Disease in the Primary Care Setting -- Part II. Coronary Artery Disease -- 9. Evaluation of Chest Pain and Myocardial Ischemia -- 10. Unstable Angina and Non-ST Elevation Myocardial Infarction -- 11. ST Elevation Myocardial Infarction -- 12. Coronary Artery Stenting -- 13. Coronary Artery Bypass Grafting -- 14. Cardiac Rehabilitation -- Part III. Peripheral Forms of Venous and Arterial Disease -- 15. Carotid Artery Disease -- 16. Peripheral Arterial Disease -- 17. Deep Venous Thrombosis and Pulmonary Embolism -- 18. Pulmonary Hypertension and Cor Pulmonale -- 19. Diagnosis and Management of Ischemic Stroke -- 20. Aortic Aneurysms -- 21. Erectile Dysfunction -- Part IV. Cardiac Disease -- 22. Valvular Heart Disease -- 23. Pericardial Diseases -- 24. Common Atrial and Ventricular Arrhythmias -- 25. Evidence-based Management of the Patient with Congestive Heart Failure -- Part V. Cardiac Imaging -- 26. Coronary Calcium Scoring -- 27. Cardiac Computed Tomography -- 28. Cardiac Magnetic Resonance Imaging.
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e-Book
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ECG interpretation made incredibly easy

https://libcat.nshealth.ca/en/permalink/provcat32881
(5th ed.) --Philadelphia, PA: Wolters Kluwer Health/Lippincott Williams & Wilkins , 2011.
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Edition
5th ed.
Place of Publication
Philadelphia, PA
Publisher
Wolters Kluwer Health/Lippincott Williams & Wilkins
Date of Publication
2011
Series Title
Incredibly easy
ISBN
9781608312894
Subjects (MeSH)
Electrocardiography - Nurses' Instruction
Arrhythmias, Cardiac - Nurses' Instruction
Contents
Cardiac anatomy and physiology -- Obtaining a rhythm strip -- Interpreting a rhythm strip -- Sinus node arrhythmias -- Atrial arrhythmias -- Junctional arrhythmias -- Ventricular arrhythmias -- Atrioventricular blocks -- Nonpharmacologic treatments -- Pharmacologic treatments -- Obtaining a 12-lead ECG -- Interpreting a 12-lead ECG.
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e-Book
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Redo Cardiac Surgery in Adults

https://libcat.nshealth.ca/en/permalink/provcat30943
Venkat R. Machiraju, Hartzell V. Schaff, Lars G. Svensson, editors. (2nd ed.) --New York, NY: Springer , c2012.
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Redo cardiac surgeries are challenging cases with a myriad of influential factors, ranging from the patient's pathology to the whimsy of the previous surgeon. Redo Cardiac Surgery in Adults, 2nd Edition clearly outlines practical approaches, surgical techniques, and management of associated conditions such as perioperative stroke and acute kidney function. It covers the spectrum of redo cardiac operations, including coronary artery bypass, mitral valve repair, reoperation for prosthetic mitral …
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Other Authors
Machiraju, Venkat R
Schaff, Hartzell V
Svensson, Lars G
Responsibility
Venkat R. Machiraju, Hartzell V. Schaff, Lars G. Svensson, editors
Edition
2nd ed.
Place of Publication
New York, NY
Publisher
Springer
Date of Publication
c2012
Physical Description
1 online resource (x, 205 p. : 95 ill., 73 ill. in color)
ISBN
9781461413264
Subjects (MeSH)
Cardiac Surgical Procedures
Heart Diseases - surgery
Reoperation
Subjects (LCSH)
Heart - Surgery
Thoracic surgery
Abstract
Redo cardiac surgeries are challenging cases with a myriad of influential factors, ranging from the patient's pathology to the whimsy of the previous surgeon. Redo Cardiac Surgery in Adults, 2nd Edition clearly outlines practical approaches, surgical techniques, and management of associated conditions such as perioperative stroke and acute kidney function. It covers the spectrum of redo cardiac operations, including coronary artery bypass, mitral valve repair, reoperation for prosthetic mitral valve endocarditis, aortic arch reoperation, descending and thoracoabdominal aortic reoperation, and reoperations following endovascular aortic repair. All redo cardiac surgeries present a complex array of challenges beyond what the original procedure demands. This book, written by an outstanding group of prominent physicians, will give the reader the knowledge and tools to approach these cases with confidence.
Contents
1. Problems Related to Redo Cardiac Surgery -- 2. Practical Approaches to the Current "On-Pump" Redo Coronary Artery Bypass Surgery -- 3. Off-Pump Coronary Artery Bypass Grafting for Repeat Coronary Revascularization -- 4. Management of Perioperative Stroke -- 5. Acute Kidney Injury Associated with Cardiac Surgery -- 6. Pulmonary Factors in Redo Open Heart Surgery -- 7. Transfusion Therapy in Reoperative Cardiac Surgery -- 8. Anesthesia for Redo Cardiac Surgery -- 9. Options for Advanced Mechanical Support for Cardiogenic Shock Complicating Cardiac Reoperations -- 10. Reoperations for Mitral Valve Disease: Surgical Approaches and Techniques -- 11. Reoperation Following Mitral Valve Repair -- 12. Reoperation for Prosthetic Mitral Valve Endocarditis -- 13. Surgical Management of Atrial Fibrillation in Redo Cardiac Operations -- 14. Surgical Management of Tricuspid Valve Disorders -- 15. Reoperation for Aortic Valve Disease -- 16. Reoperation Following Homograft Aortic Valve Replacement -- 17. Prosthetic Aortic Valve and Root Endocarditis -- 18. Reoperation on the Aortic Arch -- 19. Descending and Thoracoabdominal Aortic Reoperations -- 20. Reoperations Following Endovascular Aortic Repair -- 21. Percutaneous Approaches to Valvular Heart Disease After Previous Cardiac Surgery.
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e-Book
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Clinical Echocardiography

https://libcat.nshealth.ca/en/permalink/provcat31041
Michael Y. Henein, editor. (2nd ed.) --London: Springer , c2012.
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Echocardiography is the cornerstone of the practice of cardiology. It is used for outpatient clinics, on wards to assess patient progress and in cath labs and theatres to guide interventional procedures, device implantation and complex surgery. Yet few busy cardiologists have the time to embrace the fast-developing technology in this field and to implement in their clinical practice. Clinical echocardiography, now in a completely revised second edition, is a book that will take all the stress o…
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Henein, Michael Y
Responsibility
Michael Y. Henein, editor
Edition
2nd ed.
Place of Publication
London
Publisher
Springer
Date of Publication
c2012
Physical Description
1 online resource (xi, 317 p. : 439 ill., 303 ill. in color)
ISBN
9781848825215
Subjects (MeSH)
Echocardiography
Heart Diseases - diagnostic imaging
Ultrasonography
Subjects (LCSH)
Diagnosis, Ultrasonic
Cardiology
Abstract
Echocardiography is the cornerstone of the practice of cardiology. It is used for outpatient clinics, on wards to assess patient progress and in cath labs and theatres to guide interventional procedures, device implantation and complex surgery. Yet few busy cardiologists have the time to embrace the fast-developing technology in this field and to implement in their clinical practice. Clinical echocardiography, now in a completely revised second edition, is a book that will take all the stress out of looking at an echocardiogram and assessing exactly what is occurring in the patient's heart. This book, with its many images of almost every cardiological condition, will provide an instantaneous interpretation of the image on the screen, guiding the cardiologist through the detailed diagnostic and therapeutic steps to achieve optimum patient management and aiding the interventionist and surgeon as they carry out the necessary procedures. The book also contains up-to-date findings and summaries of academic knowledge of echocardiography, providing a useful resource for academics and researchers and suggesting ideas for further investigation.
Contents
1. Mitral Valve -- 2. Aortic Valve -- 3. Tricuspid Valve-- 4. Pulmonary Valve -- 5. Valve Substitutes -- 6. Infective Endocarditis -- 7. Coronary Artery Disease -- 8. Stress Echocardiography -- 9. Dilated Cardiomyopathy -- 10. Hypertrophic Cardiomyopathy -- 11. Restrictive Cardiomyopathy -- 12. Pulmonary Hypertension -- 13. Diseases of the Aorta -- 14. Cardiac Tumors -- 15. Pericardial Disease -- 16. Echocardiography in Simple Congenital Heart Lesions -- 17. Echocardiography in the Management of Atrial Septal Defect (ASD) and Patent Foramen Ovale (PFO) -- 18. Carotid Scanning.
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e-Book
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Echocardiography for Intensivists

https://libcat.nshealth.ca/en/permalink/provcat31254
Armando Sarti, F. Luca Lorini, editors ; forewords by A. Raffaele De Gaudio and Alfredo Zuppiroli. --Milan: Springer , c2012.
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Echocardiography has become an invaluable tool in intensive care medicine because of its ease of use and instantaneous provision of precise information on cardiovascular functional anatomy at the bedside. This book contains all the information that readers will require in order to perform echocardiography and lung ultrasound, and to interpret the findings correctly, permitting optimal guidance of the hemodynamic management of unstable patients. Furthermore, lung ultrasound is dealt with for bot…
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Sarti, Armando
Lorini, F. Luca
Responsibility
Armando Sarti, F. Luca Lorini, editors ; forewords by A. Raffaele De Gaudio and Alfredo Zuppiroli
Place of Publication
Milan
Publisher
Springer
Date of Publication
c2012
Physical Description
1 online resource (xxiii, 430 p. : 330 ill., 260 ill. in color)
ISBN
9788847025837
Subjects (MeSH)
Echocardiography
Heart Diseases - diagnostic imaging
Critical Care - methods
Subjects (LCSH)
Emergency medicine
Diagnosis, Ultrasonic
Critical care medicine
Cardiology
Abstract
Echocardiography has become an invaluable tool in intensive care medicine because of its ease of use and instantaneous provision of precise information on cardiovascular functional anatomy at the bedside. This book contains all the information that readers will require in order to perform echocardiography and lung ultrasound, and to interpret the findings correctly, permitting optimal guidance of the hemodynamic management of unstable patients. Furthermore, lung ultrasound is dealt with for both diagnosis and treatment of respiratory failure requiring mechanical ventilation. After an introductory chapter on the essential physics of ultrasonography, standard echocardiographic examination via both the transthoracic and the transesophageal approach is described. In the third section, the functional anatomy of all normal and pathologic thoracic structures as observed on echocardiography is presented in detail. A wide range of basic and advanced applications of echocardiography in the emergency and intensive care setting are then described. A final supplementary section considers further applications of ultrasound in the intensive care unit, such as ultrasound-guided vein cannulation, Doppler renal evaluation, transcranial Doppler, and lung and pleural ultrasound. This superbly illustrated book has been specifically designed to meet the needs of all intensivists, emergency physicians, and anesthesiologists who intend to use ultrasound extensively to guide optimal management of the critically ill.
Contents
[Machine generated contents note] Pt. I. Ultrasound and Use of the Echo Machine -- 1. Essential Physics of Ultrasound and Use of the Ultrasound Machine -- Pt. II. Standard Echocardiographic Examination -- 2. Ultrasound Morphology of the Heart: Transthoracic Examination -- 3. Transthoracic Echocardiography in the ICU: The Patient Who Is Difficult To Study -- 4. Ultrasound Morphology of the Heart: Transesophageal Examination -- 5. Three-Dimensional Echocardiography -- Pt. III. Essential Functional Echo-Anatomy -- 6. Left Ventricle -- 7. Right Ventricle and Pulmonary Artery -- 8. Left and Right Atria -- 9. Pericardium and Pericardial Diseases -- 10. Aorta -- 11. Inferior and Superior Venae Cavae -- 12. Ischemia and Myocardial Infarction -- 13. Cardiomyopathies -- 14. Cor Pulmonale and Pulmonary Hypertension -- 15. Mitral Valve -- 16. Aortic Valve -- 17. Tricuspid and Pulmonary Valves -- 18. Endocarditis -- 19. Prosthetic Valve Evaluation -- 20. Cardiac Tumors and Masses -- 21. Congenital Septal Abnormalities in the Adult Patient -- 22. Essential Pediatric Echocardiography -- Pt. IV. Echocardiography in the ICU and OR: Basic and Advanced Applications -- 23. Echocardiographic History, Echocardiographic Monitoring, and Goal-Directed, Focus-Oriented, and Comprehensive Examination -- 24. Intraoperative Echocardiography in Cardiac Surgery -- 25. General Hemodynamic Assessment -- 26. Contrast Echocardiography in the ICU and OR -- 27. Echo-Guided Therapy for Myocardial Ischemia -- 28. Hypovolemia and Fluid Responsiveness -- 29. ARDS, ALI, Mechanical Ventilation, and Weaning -- 30. Hypotension -- 31. Suspicion of Pulmonary Embolism -- 32. Suspicion of Acute Aortic Diseases -- 33. Chest Pain -- 34. Acute Dyspnea -- 35. Unexplained Hypoxemia -- 36. Sepsis and Septic Shock -- 37. Chest Trauma -- 38. Acute Atrial Fibrillation and Other Arrhythmias -- 39. Multiorgan Donor and Transplant Patients -- 40. New-Onset Cardiac Murmur in the Unstable Patient -- 41. ICU Echocardiography and Noninvasive Hemodynamic Monitoring: The Integrated Approach -- Pt. V. Ultrasound in the ICU: Other Applications -- 42. Echocardiography and Advanced Life Support -- 43. Central and Peripheral Vein Cannulation -- 44. Essential Ultrasonography for Venous Thrombosis -- 45. Lung and Pleural Ultrasonography in Emergency and Intensive Care -- 46. Focused Assessment with Sonography for Trauma -- 47. Renal Ultrasound and Echo-Color Doppler Techniques in Kidney Failure -- 48. Ultrasound for Percutaneous Tracheostomy -- 49. Transcranial Doppler Ultrasonography in Intensive Care -- 50. Ultrasonography of the Optic Nerve -- Appendix -- Index.
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e-Book
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Special issues in hypertension

https://libcat.nshealth.ca/en/permalink/provcat31256
Adel E. Berbari, Giuseppe Mancia, editors. --Milan: Springer , c2012.
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This volume is a cutting-edge review of the latest findings on key scientific and clinical issues in hypertension, with an integration of different new specific topics into the general knowledge of how to understand the pathophysiology and correctly diagnose and treat this chronic condition, which still represents the first cause of death in the world. Among the topics included in the book the reader will find some forms of hypertension which are frequently encountered in clinical practice and …
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Berbari, Adel E
Mancia, Giuseppe
Responsibility
Adel E. Berbari, Giuseppe Mancia, editors
Place of Publication
Milan
Publisher
Springer
Date of Publication
c2012
Physical Description
1 online resource (x, 483 p. : 69 ill.)
ISBN
9788847026018
Subjects (MeSH)
Hypertension
Subjects (LCSH)
Angiography
Cardiology
Abstract
This volume is a cutting-edge review of the latest findings on key scientific and clinical issues in hypertension, with an integration of different new specific topics into the general knowledge of how to understand the pathophysiology and correctly diagnose and treat this chronic condition, which still represents the first cause of death in the world. Among the topics included in the book the reader will find some forms of hypertension which are frequently encountered in clinical practice and on which new important evidence is available, such as high-normal blood pressure (also termed pre-hypertension), white-coat and masked hypertension, and high blood pressure in the elderly and the very elderly. These emerging aspects are discussed in detail, along with chapters on issues of great current interest, such as the way to assess and how to treat asymptomatic organ damage, emerging cardiovascular risk factors such as short and long-term blood pressure variability, cognitive impairment and dementia. The book also deals with the changing concepts in the management of hypertension and antihypertensive pharmacotherapy, and addresses specific topics which are rarely discussed in clinical medicine volumes, including hypertension in post-menopausal women, hormonal replacement therapy, inflammatory disorders, sexual dysfunction with treatment, and the effect of Ramadan fasting on blood pressure. This ready to hand but encompassing volume proves to be a comprehensive updating tool to professionals and clinical practitioners managing patients with hypertension.
Contents
1. Prehypertension: Definition, clinical significance and therapeutic approaches: to treat or not to treat -- 2. Clinical significance and treatment requirement in white coat and masked hypertension -- 3. Resistant hypertension: epidemiologic and evolving therapeutic aspects -- 4. Primary aldosteronism: rare or common condition -- 5. Hypertension in the very elderly: special features, therapeutic approaches and problems -- 6. Clinical relevance of circadian rhythm and nocturnal dip -- 7. Morning BP surge in treated and untreated hypertensive patients: clinical relevance, prognostic significance and therapeutic approaches -- 8. Short-term and long-term BP variability -- 9. Home BP in hypertension -- 10. Obstructive sleep apnea -- 11. Hypertension, obesity and the metabolic syndrome -- 12.Salt, hypertension and cardiovascular disease -- 13. Optic fundus and retinal circulation: new technology for an old examination -- 14. Arterial stiffness as an early marker of organ damage -- 15. Central blood pressure: definition, clinical significance and therapeutic approaches -- 16. Assessment of total cardiovascular risk in Hypertension: the role of subclinical organ damage -- 17. Microcirculation in hypertension -- 18. Smoking, nicotine and BP -- 19. Inflammatory markers and other risk factors in Hypertension -- 20. Benefits: pleiotropic versus BP dependent mechanisms -- 21. Threshold and target BP values for treatment: an evolving concept -- 22. Polypill concept -- 23. J-curve phenomenon: Does it exist? -- 24. Residual risk in treated hypertension -- 25. Poor BP control in the hypertensive population: which factors are involved -- 26. Ramadan fasting and BP control -- 27. Hormone replacement therapy in postmenopausal hypertensive women -- 28. Treating pain and inflammation in hypertension -- 29. Sexual function in untreated and treated hypertension -- 30. Cognitive function and dementia in hypertension. Epidemiologic and therapeutic aspects -- 31 Is hypertension preventable? -- 32. Atrial fibrillation. Modern epidemiologic and therapeutic aspects -- 33. Genetics and hypertension. Which information for clinical practice -- 34. Dual blockade of RAAS: benefits versus adverse Outcome -- 35. Long-term effects of RAAS blockade on renal function.
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e-Book
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Atlas of 3D echocardiography

https://libcat.nshealth.ca/en/permalink/provcat32036
[edited by] Edward A. Gill. --Philadelphia, PA: Elsevier Saunders , c2013.
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Other Authors
Gill, Edward A
Responsibility
[edited by] Edward A. Gill
Alternate Title
3D echocardiography
Place of Publication
Philadelphia, PA
Publisher
Elsevier Saunders
Date of Publication
c2013
Physical Description
1 online resource (xiii, 375 p.)
ISBN
9781455742387
Subjects (MeSH)
Echocardiography, Three-Dimensional - methods
Cardiovascular Diseases - diagnostic imaging
Ultrasonography
Subjects (LCSH)
Echocardiography - Atlases
Heart - Diseases - Diagnosis - Atlases
Echocardiography, Three-Dimensional - methods - Atlases
Cardiovascular Diseases - ultrasonography - Atlases
Contents
Historical perspective on three-dimensional echocardiography / Edward Gill, Berthold Klas -- Practical integration of 3D echo in the workflow of the echo lab / Lynn Weinert, Lissa Sugeng -- 3D transesophageal echocardiographic systems / Ivan S. Salgo -- Evaluation of the aortic valve by real-time three-dimensional echocardiography / Edward A. Gill -- Real time 3D echocardiography highlights : normal valve anatomy and measurements / Ernesto Salcedo and Jennifer Dorosz -- Mitral stenosis / Edward A. Gill -- Mitral regurgitation, mitral valve repair / Judy Hung and Gary Mak -- Prosthetic mitral valve evaluation / Burkhard Mackensen -- Tricuspid valve / Alicia A. Bourne and Edward A. Gill -- Pulmonary valve in health and disease by 3D echo / Edward A. Gill -- Three dimensional echo for volumetric assessment / Carly Jenkins -- Evaluation of left ventricular disynchrony by 3D echo / Cliona Kenny -- Right ventricular function assessment by 3D echo / Florence Sheehan and Mary-Pierre Waiss -- Real-time 3-dimensional echocardiographic guidance of catheter-based cardiac interventions / Nicole M. Bhave and Roberto Lang -- Three-dimensional echocardiography in congenital heart disease / Tara Bharucha and Luc Mertens -- Real-time 3D echocardiography evaluation of intracardiac masses / Elisa Zaragosa-Macias and Edward A. Gill -- Using the cropping tool to show valvular structures, the superior vena cava, atrial septal defect, and an RV pacemaker lead / Alicia Bourne ... [et al.].
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Atlas of percutaneous edge-to-edge mitral valve repair

https://libcat.nshealth.ca/en/permalink/provcat32335
Ted Feldman, Olaf Franzen, Reginald Low ... [et al.], editors. --London: Springer , c2013.
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The field of structural heart disease interventions is experiencing a stage of rapid growth with the development of percutaneous mitral valve repair therapies and percutaneous aortic valve replacement therapies. The MitraClip represents a new therapeutic frontier for mitral regurgitation and is expected to revolutionize repair of the mitral valve. For the first time in the world, physicians now have the capability to repair the mitral valve percutaneously without the need for a sternotomy or ca…
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Feldman, Ted
Responsibility
Ted Feldman, Olaf Franzen, Reginald Low ... [et al.], editors
Place of Publication
London
Publisher
Springer
Date of Publication
c2013
Physical Description
1 online resource (xvii, 591 p. : 669 ill., 587 ill. in color)
ISBN
9781447142942
Subjects (MeSH)
Mitral Valve Annuloplasty - methods
Mitral Valve Insufficiency - surgery
Mitral Valve - surgery
Percutaneous Coronary Intervention - methods
Radiography, Interventional - Atlases
Subjects (LCSH)
Interventional radiology
Cardiology
Abstract
The field of structural heart disease interventions is experiencing a stage of rapid growth with the development of percutaneous mitral valve repair therapies and percutaneous aortic valve replacement therapies. The MitraClip represents a new therapeutic frontier for mitral regurgitation and is expected to revolutionize repair of the mitral valve. For the first time in the world, physicians now have the capability to repair the mitral valve percutaneously without the need for a sternotomy or cardiopulmonary bypass. However, as with all new endeavors, there is a steep learning curve, not just for the individual operator but also for the entire field. The MitraClip technology and technique is technically complex and is guided by echocardiography and fluoroscopy. It is an imaging intensive procedure that requires deep 3-dimensional understanding of normal and abnormal cardiac anatomy. Not all mitral regurgitation cases are suitable and not all cases are straightforward. It is therefore crucially important for physicians in this specialty to communicate their experience, successes, failures and complications with each other. Written by the leaders in this breakthrough field, the Atlas of Percutaneous Edge-to-Edge Mitral Valve Repair is the first of its kind for the new percutaneous MitraClip procedure. The Editors have designed the book to be a comprehensive reference manual and to provide cardiologists with true examples of basic and complex cases of percutaneous mitral valve repair using the technology. In addition, this book provides step-by-step guides to the procedure and complications as well as steps to recover from them are discussed. The Atlas is anticipated to be a very valuable reference for both novice and experienced interventional cardiologists and echocardiologists. As percutaneous valve repair becomes more common it will also be of great interest to general cardiologists and surgeons.
Contents
Foreword. Introduction.Mitral Valve Anatomy and Current Surgical and Percutaneous Approaches to Mitral Regurgitation.Device description and procedural overview. Room Set-up.Summary of MitraClip Clinical Data and Approach to Patient Selection. Echocardiographic Evaluation of Patients Before and After MitraClip Mitral Valve Repair.MitraClip Procedural Echocardiography. Transseptal puncture. Venous Access Management -- Hemodynamic perspectives of edge-to-edge mitral valve repair -- Situational Steering Techniques -- Case example: EVEREST II: Basic Degenerative. Case example: EVEREST II: Basic Functional. Case example: Barlow's disease -- Case example: EVEREST II : Large left atrium -- Case example: Approach to Mitral Regurgitation requiring multiple MitraClips -- Case example: Two Clips. Case example: EVEREST II: Delayed second clip for early recurrent mitral regurgitation. Case example: Secondary mitral regurgitation due to ischaemic mitral valve disease and mild rheumatic mitral valve involvement. Case example: The dilemma of reducing functional mitral regurgitation versus development of mitral stenosis. Case example: Infective endocarditis associated with the Mitraclip -- Case example: EVEREST II: MitraClip after failed surgical mitral valve repair. Case example: EVEREST II: Functional Mitral Regurgitation. Case example: Chiari Network Complicating a MitraClip Procedure. Case example: EVEREST II: Two MitraClip Procedure with Partial Detachment of Second Device -- Case example: Mitraclip Procedure in Unusual Heart Position -- Interatrial Septal Tear: A rare complication during MitraClip procedure and successful transcatheter closure. Case example: Percutaneous double-valve treatment in a patient with degenerative aortic stenosis and functional mitral regurgitation -- Case example: Percutaneous mitral valve repair after previous mitral valve reconstruction -- Case example: Delayed functional Mitral Regurgitation in high risk patients and Complex degenerative mitral regurgitation (anterior leaflet prolapsed) with commissural impingement -- Case example: Severe functional mitral regurgitation with missing leaflet coaptation -- Case example: Severe Ischemic Heart Failure with Functional Improvement After MitraClip Therapy -- Case example: Severe left-to-right shunting from iatrogenic atrial septal defect -- Case example: MitraClip implantation in chronic degenerative mitral regurgitation with extensive calcification -- Case example: 3D Transesophageal Echo Guided MitraClip Treatment of P3 Mitral Valve Prolapse -- Case example: Failure and complications of a MitraClip implantation for severe functional mitral regurgitation: a combination of unexpected findings and early experience -- Case example: Mitral valve repair using the MitraClip system in a patient with severe mitral regurgitation in the A3/P3 region due to chordae rupture during transapical TAVI -- Case example: MitraClip implantation in a patient with severe mitral annulus calcifications and a small orifice area.Çô Case example: Functional Mitral Regurgitation treatment with Mitraclip: Difficult transseptal puncture with anterior approach complicated by right atrial thrombus -- Case example: MitraClip in a patient with dextrocardia and scoliosis complicated by delayed clip detachment. Case example: Massive air embolism during MitraClip insertion -- Case example: The degree and type of mitral regurgitation present at the baseline is not always a good predictor of the procedural technical needs and of the final result -- Case example: Functional mitral regurgitation with a wide extension of the central regurgitant jet -- Case example: Percutaneous edge-to-edge mitral valve repair for functional mitral regurgitation in a high surgical risk patient -- Case example: Mitral stenosis after MitraClip therapy and a partial solution for treatment -- Case Example: MitraClip Therapy for Functional Mitral Regurgitation: Importance of jet localization to direct MitraClip placement -- Case Example: MitraClip: Acute thrombus formation during guide insertion -- MitraClip Placement in a Patient with Severe Kyphoscoliosis and Bileaflet Prolapse.
Format
e-Book
Location
Online
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Drug Therapy for the Elderly

https://libcat.nshealth.ca/en/permalink/provcat32518
Martin Wehling, editor. --Vienna: Springer , c2013.
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With people aged 65 years and older currently making up the fastest growing age group throughout the world, the demographic revolution of an aging society will inevitably lead to increased pressure to develop a rationalistic and age-tailored process of diagnosis and treatment among the elderly. As aging people often suffer from several chronic diseases and are being treated with multiple medications concurrently, unwanted drug interactions occur more frequently. Whereas recent approaches have …
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Author
Wehling, Martin
Responsibility
Martin Wehling, editor
Place of Publication
Vienna
Publisher
Springer
Date of Publication
c2013
Physical Description
1 online resource (xv, 356 p. : 53 ill., 35 ill. in color)
ISBN
9783709109120
Subjects (MeSH)
Geriatrics - methods
Subjects (LCSH)
Toxicology
Geriatrics
Pharmacy
Abstract
With people aged 65 years and older currently making up the fastest growing age group throughout the world, the demographic revolution of an aging society will inevitably lead to increased pressure to develop a rationalistic and age-tailored process of diagnosis and treatment among the elderly. As aging people often suffer from several chronic diseases and are being treated with multiple medications concurrently, unwanted drug interactions occur more frequently. Whereas recent approaches have recommended to remove particular drugs from the medication regimen to avoid adverse effects, Drug Therapy for the Elderly underlines both indispensable and dispensable elements of drug treatment, providing the practitioner with: Background information on the elderly population regarding their needs for particular drugs (with an eye to frailty, co-morbidity patterns, and special sensitivities regarding drug metabolism and excretion); Practical advice about drug treatment surveillance parameters in the elderly; In-depth discussion of drugs in relation to the elderly with specific diagnoses; Integration of multimorbidity/polypharmacy situations into prioritization schemes; A plan for how to deal with the complexity of polypharmacy situations in a five-minute consultation. An original classification of drugs is proposed by the editor which relates the power of effects, prognostic data, and tolerability to a prioritization scoring system. This approach is the first to not only provide a negative listing, but also integrates positive data into an overall assessment for drugs fit for the aged. Therefore, Drug Therapy for the Elderly serves as a timely reference for a wide array of physicians.
Contents
General Aspects -- Heterogeneity and Vulnerability of Older Patients -- Epidemiologic Aspects -- Age-Associated General Pharmacological Aspects -- Critical Extrapolation of Guidelines and Study Results: Risk-Benefit Assessment for Patients with Reduced Life Expectancy and a New Classification of Drugs According to Their Fitness for the Aged -- Inappropriate Medication Use and Medication Errors in the Elderly -- Special Aspects with Respect to Organ Systems Based on Geriatric Clinical Importance -- Arterial Hypertension -- Heart Failure -- Coronary Heart Disease and Stroke -- Atrial Fibrillation -- Diabetes Mellitus -- Obstructive Lung Diseases -- Osteoporosis -- Parkinson’s Disease -- Therapy of Chronic Pain -- Dementia -- Depression -- Sleep Disorders -- Treatment Decisions and Medical Treatment of Cancer in Elderly Patients -- Pharmacotherapy and Geriatric Syndromes -- Fall Risk and Pharmacotherapy -- Central Nervous System (CNS) Medications and Delirium -- Pharmacotherapy and Special Aspects of Cognitive Disorders in the Elderly -- Pharmacotherapy and Incontinence -- Immobility and Pharmacotherapy -- Pharmacotherapy and the Frailty Syndrome -- Further Problem Areas in Gerontopharmacotherapy and Pragmatic Recommendations -- Adherence to Pharmacotherapy in the Elderly -- Polypharmacy -- Inappropriate Prescribing in the Hospitalized Elderly Patient -- Index.
Format
e-Book
Location
Online
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Electrical diseases of the heart. Volume 1, Basic foundations and primary electrical diseases

https://libcat.nshealth.ca/en/permalink/provcat32557
Ihor Gussak, Charles Antzelevitch (eds.) ; Arthur A.M. Wilde, Brian D. Powell, Michael J. Ackerman, and Win-Kuang Shen (co-eds.). (2nd edition) --London: Springer , c2013.
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Location
Online
The past two decades have witnessed an explosion of knowledge and radical changes in our understanding of the molecular, ionic, genetic, and pharmacologic basis of electrical diseases of the heart. Electrical diseases of the heart are heritable arrhythmogenic clinical entities that may share common clinical and genetic features, yet may be distinctly different in their genesis, prognosis, and management. Notably, both congenital and acquired electrical diseases of the heart are receiving increa…
Available Online
View e-Book
Other Authors
Gussak, Ihor
Antzelevitch, Charles
Responsibility
Ihor Gussak, Charles Antzelevitch (eds.) ; Arthur A.M. Wilde, Brian D. Powell, Michael J. Ackerman, and Win-Kuang Shen (co-eds.)
Edition
2nd edition
Place of Publication
London
Publisher
Springer
Date of Publication
c2013
Physical Description
1 online resource
ISBN
9781447148814
Subjects (MeSH)
Arrhythmias, cardiac
Heart - physiology
Heart Diseases - physiopathology
Subjects (LCSH)
Medicine
Internal medicine
Cardiology
Neurology
Epidemiology
Abstract
The past two decades have witnessed an explosion of knowledge and radical changes in our understanding of the molecular, ionic, genetic, and pharmacologic basis of electrical diseases of the heart. Electrical diseases of the heart are heritable arrhythmogenic clinical entities that may share common clinical and genetic features, yet may be distinctly different in their genesis, prognosis, and management. Notably, both congenital and acquired electrical diseases of the heart are receiving increased recognition as a result of important advances in genetic analysis. In this second edition of Electrical Diseases of the Heart, the Editors' goal has been to embrace and highlight the explosion of knowledge that our field has witnessed since the publication of the first edition. The approach continues to be one of bridging basic and clinical science in an attempt to advance meaningfully our understanding of heart disease and identify the knowledge gaps that exist. This volume covers the basic foundations and primary electrical diseases and with the companion volume provides the latest developments in the field of experimental and clinical cardiac electrophysiology, genetics, pharmacology and interventional therapies of various clinical arrhythmogenic entities. Residents, fellows and physicians in cardiology and electrophysiology will gain valuable insight into the latest developments in the field of cardiac electrophysiology and clinical electrocardiology by reading this book, including expert review of the genetic and epidemiologic considerations, diagnostic and therapeutic modalities of the newly discovered clinical syndromes and electrocardiographic phenomena, and their correlation with the most recent advances in the basic science.
Contents
Part I. Basic Fundamentals of Normal and Abnormal Cardiac Electrical Activity -- 1. Introduction to Part I: Basic Cardiac Electrophysiology – Promises Kept and Promises to Keep -- 2. Basic Physiology of Ion Channel Function -- 3. Developmental Aspects of the Electrophysiology of the Heart: Function Follows Form -- 4. Anatomic and Histopathologic Characteristics of the Conductive Tissues of the Heart -- 5. Neural Regulation of the Heart in Health and Disease -- 6. Mechanisms of Cardiac Arrhythmia -- 7. Mechanisms of Action of Antiarrhythmic Drugs in Ventricular Arrhythmias -- 8. Mechanisms of Action of Antiarrhythmic Drugs in Atrial Fibrillation -- 9. Mechano-Electric Interactions and Their Role in Electrical Function of the Heart -- 10. Pathological Roles of the Cardiac Sodium Channel Late Current (Late INa) -- 11. Sodium Ion Channelopathies -- 12. L-Type Calcium Channel Disease -- 13. Nerve Sprouting, Defibrillation and Calcium Waves -- 14. K+ Channelopathies (IKs, IKr, and Ito) -- 15. Cardiac ATP-Sensitive Potassium Channels and Associated Channelopathies -- 16. Cardiac KATP Channels in Health and Diseases -- 17. Ca2+ Release Channels (Ryanodine Receptors) and Arrhythmogenesis -- 18. Caveolae and Arrhythmogenesis -- 19. Senescence and Arrhythmogenesis -- 20. Comparisons of Substrates Responsible for Atrial Versus Ventricular Fibrillation -- 21. Single Nucleotide Polymorphisms in Health and Cardiac Disease -- 22. Electrophysiological Remodeling in Heart Failure -- 23. Ventricular Electrical Remodeling in Compensated Cardiac Hypertrophy -- 24. Physiological and Other Biological Pacemakers -- 25. Cardiac Memory: From Electrical Curiosity to Clinical Diagnostic and Research Tool -- Part II. Heritable Arrhythmogenic Channelopathies, Primary Electrical Diseases, and Sudden Cardiac Death -- 26. Introduction to Part Two: Celebrating the Challenge of Cardiac Arrhythmias -- 27. Congenital Long QT Syndrome -- 28. Brugada Syndrome: Clinical and Genetic Aspects -- 29. Brugada Syndrome: Cellular Mechanisms and Approaches to Therapy -- 30. Early Repolarization Syndrome: Epidemiology, Genetics, and Risk Stratification -- 31. Catecholaminergic Polymorphic Ventricular Tachycardia -- 32. Andersen-Tawil and Timothy Syndromes -- 33. Short QT Syndrome -- 34. Progressive Cardiac Conduction Disease -- 35. Genetics of Atrial Fibrillation and Standstill -- 36. Idiopathic Ventricular Fibrillation.
Format
e-Book
Location
Online
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Handbook of oral anticoagulation

https://libcat.nshealth.ca/en/permalink/provcat33540
editors, Gregory YH Lip, Eduard Shantsila ; contributors, Deirdre A. Lane, Chee W. Khoo, Kok Hoon Tay, Suresh Krishnamoorthy, Stavros Apostolakis. (Second edition) --London: Springer Healthcare , c2013.
Available Online
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Location
Online
This book covers a wide range of disorders such as atrial fibrillation, artificial heart valves, deep vein thrombosis, pulmonary embolism and stroke. Handbook of Oral Anticoagulation aims to provide an accessible overview of the exciting new developments in this field. Incorporating numerous quick-reference tables and figures and fully referenced throughout to key papers and the latest reviews, it will be a useful resource for all healthcare professionals involved in thromboprophylaxis.
Available Online
View e-Book
Other Authors
Lip, Gregory Y. H
Shantsila, Eduard
Responsibility
editors, Gregory YH Lip, Eduard Shantsila ; contributors, Deirdre A. Lane, Chee W. Khoo, Kok Hoon Tay, Suresh Krishnamoorthy, Stavros Apostolakis
Edition
Second edition
Place of Publication
London
Publisher
Springer Healthcare
Date of Publication
c2013
Physical Description
1 online resource (ix, 88 pages)
ISBN
9781908517968 (electronic bk.)
9781908517586
Subjects (MeSH)
Anticoagulants - administration & dosage
Anticoagulants - adverse effects
Anticoagulants - therapeutic use
Subjects (LCSH)
Anticoagulants - Handbooks
Anticoagulants (Medicine)
Cardiology
Hematology
General Practice / Family Medicine
Primary Care Medicine
Pharmacotherapy
Abstract
This book covers a wide range of disorders such as atrial fibrillation, artificial heart valves, deep vein thrombosis, pulmonary embolism and stroke. Handbook of Oral Anticoagulation aims to provide an accessible overview of the exciting new developments in this field. Incorporating numerous quick-reference tables and figures and fully referenced throughout to key papers and the latest reviews, it will be a useful resource for all healthcare professionals involved in thromboprophylaxis.
Contents
The Coagulation Pathway and Approaches to Anticoagulation -- Common Clinical Indications for Anticoagulation -- Vitamin K Antagonists and Their Limitations -- Hemorrhage Risks, Patient Perspectives, and Quality-of-Life Issues -- New Oral Anticoagulants -- Future Directions.
Format
e-Book
Location
Online
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Electrical Diseases of the Heart. Volume 2, Diagnosis and Treatment

https://libcat.nshealth.ca/en/permalink/provcat40706
Ihor Gussak, Charles Antzelevitch (eds.) ; Arthur A.M. Wilde, Brian D. Powell, Michael J. Ackerman, and Win-Kuang Shen (co-eds.). (2nd edition) --London: Springer , c2013.
Available Online
View e-Book
Location
Online
The past two decades have witnessed an explosion of knowledge and radical changes in our understanding of the molecular, ionic, genetic, and pharmacologic basis of electrical diseases of the heart. Electrical diseases of the heart are heritable arrhythmogenic clinical entities that may share common clinical and genetic features, yet may be distinctly different in their genesis, prognosis, and management. Notably, both congenital and acquired electrical diseases of the heart are receiving increa…
Available Online
View e-Book
Other Authors
Gussak, Ihor
Antzelevitch, Charles
Responsibility
Ihor Gussak, Charles Antzelevitch (eds.) ; Arthur A.M. Wilde, Brian D. Powell, Michael J. Ackerman, and Win-Kuang Shen (co-eds.)
Edition
2nd edition
Place of Publication
London
Publisher
Springer
Date of Publication
c2013
Physical Description
1 online resource (xxii, 682 p. : 161 illus., 52 illus. in color)
ISBN
9781447149781
9781447149774 (print ed.)
Subjects (MeSH)
Arrhythmias, cardiac
Electrophysiologic Techniques, Cardiac
Heart - physiology
Risk Factors
Abstract
The past two decades have witnessed an explosion of knowledge and radical changes in our understanding of the molecular, ionic, genetic, and pharmacologic basis of electrical diseases of the heart. Electrical diseases of the heart are heritable arrhythmogenic clinical entities that may share common clinical and genetic features, yet may be distinctly different in their genesis, prognosis, and management. Notably, both congenital and acquired electrical diseases of the heart are receiving increased recognition as a result of important advances in genetic analysis. In this second edition of Electrical Diseases of the Heart, the Editors' goal has been to embrace and highlight the explosion of knowledge that our field has witnessed since the publication of the first edition. The approach continues to be one of bridging basic and clinical science in an attempt to advance meaningfully our understanding of heart disease and identify the knowledge gaps that exist. This volume covers the diagnostic and treatment options available in the management of electrical diseases and with its companion volume provides the latest developments in the field of experimental and clinical cardiac electrophysiology, genetics, pharmacology and interventional therapies of various clinical arrhythmogenic entities. Residents, fellows and physicians in cardiology and electrophysiology will gain valuable insight into the latest developments in the field of cardiac electrophysiology and clinical electrocardiology by reading this book, including expert review of the genetic and epidemiologic considerations, diagnostic and therapeutic modalities of the newly discovered clinical syndromes and electrocardiographic phenomena, and their correlation with the most recent advancesáin the basic science.
Contents
Part I. Secondary Hereditary and Acquired Cardiac Channelopathies and Sudden Cardiac Death -- 1. Introduction to Part Three: Cardiac Remodeling -- 2. Arrhythmias and Arrhythmia Management in Hypertrophic Cardiomyopathy -- 3. Sudden Cardiac Death in Dilated Cardiomyopathy and Skeletal Muscular Dystrophy -- 4. Arrhythmogenic Right Ventricular Cardiomyopathy/Dysplasia -- 5. The Wolff-Parkinson-White Syndrome and the Risk of Sudden Death -- 6. Acquired (Drug-Induced) Long and Short QT Syndromes -- 7. Acquired Form of Brugada Syndrome -- Part II. Clinical Rhythmology: Diagnostic Methods and Tools -- 8. Introduction to Part IV: Abnormal Electrical Functions of the Heart and Their Diagnoses in Clinic -- 9. Diagnostic Electrocardiography -- 10. Microvolt T Wave Alternans: Mechanisms and Implications for Prediction of Sudden Cardiac Death -- 11. Heart Rate Variability: Measurements and Risk Stratification -- 12. Orthostatic Challenge Tests: Active Standing and Head-Up Tilt -- 13. Signal Averaged ECG -- 14. Surface Mapping and Magneto-Electrocardiography -- 15. Ambulatory Monitoring: (Holter, Event Recorders, External, and Implantable Loop Recorders and Wireless Technology) -- 16. Device Therapy for Remote Patient Management -- 17. Invasive Electrophysiologic Testing: Role in Sudden Death Prediction -- 18. Provocative (Drug) Testing in Inherited Arrhythmias -- 19. Novel Predictors of Sudden Cardiac Death -- 20. Genetic Testing -- Part III. Risk Stratification of Sudden Cardiac Death in Acquired Clinical Conditions -- 21. Introduction to Part Five: Screening for Risk of Sudden Cardiac Death -- 22. Risk Stratification for Sudden Death in Patients with Coronary Artery Disease -- 23. Sudden Death in Athletes -- 24. Cardiac Channelopathies and Sudden Infant Death Syndrome -- 25. Heart Failure and Sudden Death -- 26. Neurologic Conditions and Sudden Death -- 27. Sudden Cardiac Death and Alcohol -- 28. Sudden Cardiac Death and Addictive Chemical Substances -- 29. Obstructive Sleep Apnea and Sudden Death -- 30. Sudden Cardiac Arrest in Chronic Kidney Disease -- 31. Clinical Trials in Sudden Cardiac Death Prevention: Principles and Endpoints -- Part IV. Treatment and Prevention Modalities -- 32. Introduction to Part IV: Treatment Modalities -- 33. Clinical Role of Antiarrhythmic Drugs in the Prevention of Sudden Death -- 34. Non-antiarrhythmic Drugs in Sudden Death Prevention -- 35. Non-surgical Treatment and Prevention of Atrial Fibrillation -- 36. Surgical Treatment of Atrial Fibrillation -- 37. Catheter Ablation for Triggered Ventricular Fibrillation and Polymorphic Ventricular Tachycardia -- 38. Catheter Ablation for Scar-Dependent Ventricular Tachycardia -- 39. The Implantable Cardioverter Defibrillator: Technical and Clinical Considerations -- 40. Beyond Sudden Death Prevention: Minimizing ICD Shocks and Morbidity, and Optimizing Efficacy -- 41. Pacing and Cardiac Resynchronization.
Format
e-Book
Location
Online
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CT Atlas of Adult Congenital Heart Disease

https://libcat.nshealth.ca/en/permalink/provcat40707
Wojciech Mazur, Marilyn J. Siegel, Tomasz Miszalski-Jamka, Robert Pelberg. --London: Springer , c2013.
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Improvements in surgical and medical management of congenital heart disease (CHD) result in an increased life expectancy and a greater number of children living into adulthood. Consequently, adult cardiologists are caring for increasing numbers of patients with congenital heart defects. In many instances, these patients have undergone palliative but not corrective procedures and may be at higher risk of cardiovascular morbidity and mortality. In the past several years, the use of CT angiography…
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Author
Mazur, Wojciech
Other Authors
Siegel, Marilyn J
Miszalski-Jamka, Tomasz
Pelberg, Robert
Responsibility
Wojciech Mazur, Marilyn J. Siegel, Tomasz Miszalski-Jamka, Robert Pelberg
Place of Publication
London
Publisher
Springer
Date of Publication
c2013
Physical Description
1 online resource (xix, 367 p. : 330 illus., 125 illus. in color)
ISBN
9781447150886
9781447150879 (print ed.)
Subjects (MeSH)
Heart Defects, Congenital - diagnostic imaging
Radiography
Tomography, X-Ray Computed
Abstract
Improvements in surgical and medical management of congenital heart disease (CHD) result in an increased life expectancy and a greater number of children living into adulthood. Consequently, adult cardiologists are caring for increasing numbers of patients with congenital heart defects. In many instances, these patients have undergone palliative but not corrective procedures and may be at higher risk of cardiovascular morbidity and mortality. In the past several years, the use of CT angiography (CTA) has increased, driven mainly by technical improvements that allow shorter imaging times and high spatial and temporal resolution. Thus, CTA combines widespread availability with the advantages of volumetric data acquisition, short acquisition times, and the possibility of simultaneous evaluation of myocardial and extracardiac structures, ventricular function and coronary anatomy making it a very appealing imaging modality in CHD patients. CT Atlas of Adult Congenital Heart Disease is an all inclusive, invaluable tool to describe the features of classic CHD, hereditary cardiomyopathies and aortopathies. It includes comprehensive pathology descriptions and discussions of the utility of CTA in the diagnosis of all forms of adult CHD. The many CTA images and illustrations demonstrate the pathologies and provide a framework for recognizing patterns of CHD in adult patients. It also includes pre-procedural pediatric CHD cases to allow better understanding of CHD anatomy and pathophysiology, and thus will be essential reading for all pediatric and adult cardiologists and radiologists involved in the management of these patients.
Contents
Part I. Embyology and the Normal Heart -- Cardiac Embryology -- The Normal Heart -- Normal Anatomic Variants and Imaging Artifacts Mimicking Pathology -- Part II. Basic Nomenclature and Approach to Evaluating Congenital Heart Disease Imaging -- Basic nomenclature and Approach to Evaluating Congenital Heart Disease Imaging -- Basic Nomenclature in Adult Congenital Heart Disease -- Segmental, Sequential Approach to CT Interpretation in Adult Congenital Heart Disease -- Part III. CT Imaging Techniques in Adult Congenital Heart Disease -- Technical Principles in CT Imaging of Adult Congenital Heart Disease -- Part IV. Congenital Dysplasias and Cardiomyopathies -- Arrythmogenic Right Ventricular Dysplasia -- Uhl Anomaly -- Isolated Left Ventricular Noncompaction (LVNC) -- Hyperthrophic Cardiomiopathy -- Part V. Anomalies with Normal Chamber and Valve Sequence and Position -- Septal Defects -- Atrioventricular valve abnormalities -- Left ventricular outflow tract abnormalities -- Right ventricular outflow tract obstruction -- Arterial Anomalies -- Coronary Artery Anomalies -- Congenital Venous Anomalies -- Part VI. Anomalies with Abnormal Chamber Sequence or Relationship -- Abnormal Relationship between Atria and Ventricles -- Abnormal Relationships between Ventricles and Great Vessels -- Heterotaxy syndrome -- Part VII. Palliative and Corrective Procedures in Adult Congenital Heart Disease -- Percutaneous Closures -- Aortopulmonary Shunts: Blalock–Taussig, Potts, Waterston -- Atrial Baffles for the Treatment of Transposition of the Great Arteries (Mustard, Senning) -- Arterial Switch Operation for Transposition of the Great Arteries -- Systemic Vein to Pulmonary Artery Shunts: Glenn, Fontan, and Kawashima Procedures -- Rastelli Procedure -- Damus-Kaye-Stansel Procedure -- Double-Switch Procedure -- Tetrology of Fallot Repair -- Ross Procedure -- Norwood Procedure and Sano Modification -- Aortic Coarctation Repairs -- Part VIII. Congenital Pericardial Abnormalites -- Congenital Absence of the Pericardium.
Format
e-Book
Publication Type
Atlas
Location
Online
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Marc Dewey. (Second edition) --Berlin: Springer , c2014.
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Location
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Cardiac computed tomography (CT) has become a highly accurate diagnostic modality that continues to attract increasing attention. This extensively illustrated book aims to assist the reader in integrating cardiac CT into daily clinical practice, while also reviewing its current technical status and applications. Clear guidance is provided on the performance and interpretation of imaging using the latest technology, which offers greater coverage, better spatial resolution, and faster imaging whi…
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Author
Dewey, Marc
Responsibility
Marc Dewey
Edition
Second edition
Place of Publication
Berlin
Publisher
Springer
Date of Publication
c2014
Physical Description
1 online resource (xiii, 498 pages : illustrations)
ISBN
9783642418839 (electronic bk.)
9783642418822
Subjects (MeSH)
Cardiovascular Diseases - diagnostic imaging
Tomography, Emission-Computed
Subjects (LCSH)
Cardiovascular system - Tomography
Abstract
Cardiac computed tomography (CT) has become a highly accurate diagnostic modality that continues to attract increasing attention. This extensively illustrated book aims to assist the reader in integrating cardiac CT into daily clinical practice, while also reviewing its current technical status and applications. Clear guidance is provided on the performance and interpretation of imaging using the latest technology, which offers greater coverage, better spatial resolution, and faster imaging while also providing functional information about cardiac diseases. The specific features of scanners from all four main vendors, including those that have only recently become available, are presented. Among the wide range of applications and issues discussed are coronary calcium scoring, coronary artery bypass grafts, stents, and anomalies, cardiac valves and function, congenital and acquired heart disease, and radiation exposure. Upcoming clinical uses of cardiac CT, such as hybrid imaging, preparation and follow-up after valve replacement, electrophysiology applications, myocardial perfusion and fractional flow reserve assessment, and plaque imaging, are also explored.
Contents
Introduction -- Technical and Personnel Requirements -- Anatomy -- Cardiac CT in Clinical Practice -- Clinical Indications -- Patient Preparation -- Physics Background and Radiation Exposure -- Examination and Reconstruction -- Examinations on Different CT Scanners -- Reading and Reporting -- Coronary Artery Calcium -- Coronary Artery Bypass Grafts -- Coronary Artery Stents -- Coronary Artery Plaques -- Cardiac Function -- Cardiac Valves -- Transcatheter Aortic Valve Interventions -- Pulmonic Valve Implantation, Mitral Valve Repair, and Left Atrial Appendage Closure -- Myocardial Perfusion and Fractional Flow Reserve -- Hybrid Imaging -- Electrophysiology Interventions -- Coronary Artery Anomalies -- Congenital and Acquired Heart Disease -- Typical Clinical Examples -- Results of Clinical Studies -- Outlook.
Format
e-Book
Location
Online
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Essentials of atrial fibrillation

https://libcat.nshealth.ca/en/permalink/provcat33365
Yee Guan Yap, A John Camm. ([Revised edition]) --London: Springer Healthcare , c2014.
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Location
Online
Available Online
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Author
Yap, Yee Guan
Other Authors
Camm, A. John
Responsibility
Yee Guan Yap, A John Camm
Edition
[Revised edition]
Place of Publication
London
Publisher
Springer Healthcare
Date of Publication
c2014
Physical Description
1 online resource (viii, 47 pages)
ISBN
9781907673986 (electronic bk.)
9781858734385
Subjects (MeSH)
Atrial Fibrillation
Subjects (LCSH)
Atrial fibrillation
Internal Medicine
Cardiology
Hematology
Contents
1. Epidemiology of atrial fibrillation -- 2. Pathogenesis of atrial fibrillation -- 3. Classification, diagnosis, and assessment of atrial fibrillation -- 4. Rate and rhythm control strategies for atrial fibrillation -- 5. Anticoagulant treatment strategies for atrial fibrillation.
Format
e-Book
Location
Online
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134 records – page 1 of 7.