Drug Allergy : Clinical Aspects, Diagnosis, Mechanisms, Structure-Activity Relationships
https://libcat.nshealth.ca/en/permalink/provcat40747
Brian A. Baldo, Nghia H. Pham.
--New York, NY:
Springer
, c2013.
- Available Online
- View e-Book
- Location
- Online
The variety of chemically diverse pharmacological agents administered to patients is large and continues to expand and with every new drug released, there is always potential for adverse reactions, some of them allergic. With its roots in immunology and pharmacology, the science of drug allergy is becoming better understood and applied as its importance is increasingly recognized throughout the many branches of medicine. Drug Allergy: Clinical Aspects, Diagnosis, Mechanisms, Structure-Activity …
- Available Online
- View e-Book
- Author
- Baldo, Brian A
- Other Authors
- Pham, Nghia H
- Responsibility
- Brian A. Baldo, Nghia H. Pham
- Place of Publication
- New York, NY
- Publisher
- Springer
- Date of Publication
- c2013
- Physical Description
- 1 online resource (xviii, 447 p. : 228 illus., 70 illus. in color)
- ISBN
- 9781461472612
- 9781461472605 (print ed.)
- Subjects (MeSH)
- Drug Hypersensitivity
- Drug Hypersensitivity - diagnosis
- Structure-Activity Relationship
- Abstract
- The variety of chemically diverse pharmacological agents administered to patients is large and continues to expand and with every new drug released, there is always potential for adverse reactions, some of them allergic. With its roots in immunology and pharmacology, the science of drug allergy is becoming better understood and applied as its importance is increasingly recognized throughout the many branches of medicine. Drug Allergy: Clinical Aspects, Diagnosis, Mechanisms, Structure-Activity Relationships sheds new light on this field. Comprehensive in design, this authoritative title identifies the most important culprit drugs implicated in immediate and delayed drug hypersensitivities and offers up-to-date information on classifications, the many different drug-induced systemic and cutaneous reactions, diagnoses, underlying mechanisms and structure-activity relationships. Chapters dealing with the molecular and cellular mechanisms of drug hypersensitivities, non-immune-mediated sensitivities and diagnostic methods are presented as introductory material for in-depth treatises on the ø-lactam antibiotics, other antibiotics and antimicrobials, drugs used in anesthesia and surgery, opioid analgesics, corticosteroids, monoclonal antibodies and other biologics, drugs used in chemotherapy, proton pump inhibitors, iodinated and gadolinium-based contrast media and non-steroidal anti-inflammatory drugs. In addition to being of immense value to clinicians, other health care professionals and researchers, this title will prove invaluable for those taking undergraduate and graduate courses in the biomedical sciences and will also serve as a useful text for students of medicine, pharmacy, nursing and dentistry.
- Contents
- 1. Adverse Reactions to Drugs and Drug Allergy: Scope of this Book -- 2. Classification and Descriptions of Allergic Reactions to Drugs -- 3. Mechanisms of Hypersensitivity -- 4. Diagnosis of Allergic Reactions to Drugs -- 5. ø-Lactam Antibiotics -- 6. Other Antimicrobial Drugs -- 7. Drugs and Other Agents Used in Anesthesia and Surgery -- 8. Opioid Analgesic Drugs -- 9. Non-Steroidal Anti-Inflammatory Drugs -- 10. Contrast Media -- 11. Biologics -- 12. Corticosteroids -- 13. Drugs Used for Chemotherapy -- 14. Proton Pump Inhibitors -- Postface.
- Format
- e-Book
- Location
- Online
Drug Allergy : Clinical Aspects, Diagnosis, Mechanisms, Structure-Activity Relationships
https://libcat.nshealth.ca/en/permalink/provcat46495
Brian A. Baldo, Nghia H. Pham.
(Second edition)
--Cham:
Springer
, c2021.
- Available Online
- View e-Book
- Access
- NEW Springer 2021
- Location
- Online
The second edition of this book spans the broad range of modern therapeutic drugs, from small molecules to biologic recombinant proteins. It offers a comprehensive review of the classification and description of different drug-induced systemic and cutaneous hypersensitivities; an up-to-date coverage of individual culprit drugs in each group of therapeutics; the diagnosis and mechanisms of reactions; and important structure-activity relationships. New content expands to two areas of drug allergy…
- Available Online
- View e-Book
- Author
- Baldo, Brian A.
- Other Authors
- Pham, Nghia H.
- Responsibility
- Brian A. Baldo, Nghia H. Pham
- Edition
- Second edition
- Place of Publication
- Cham
- Publisher
- Springer
- Date of Publication
- c2021
- Physical Description
- 1 online resource (xxii, 732 p.) : 330 illus., 162 illus. in color
- ISBN
- 9783030517403
- 9783030517397 (Print ed.)
- 9783030517410 (Print ed.)
- 9783030517427 (Print ed.)
- Subjects (MeSH)
- Drug Hypersensitivity
- Drug-Related Side Effects and Adverse Reactions
- Structure-Activity Relationship
- Specialty
- Allergy and Immunology
- Pharmacology
- Toxicology
- Abstract
- The second edition of this book spans the broad range of modern therapeutic drugs, from small molecules to biologic recombinant proteins. It offers a comprehensive review of the classification and description of different drug-induced systemic and cutaneous hypersensitivities; an up-to-date coverage of individual culprit drugs in each group of therapeutics; the diagnosis and mechanisms of reactions; and important structure-activity relationships. New content expands to two areas of drug allergy that have recently experienced explosive growth: biological therapies and new targeted chemotherapies. Other new and expanded chapters address antimicrobials; drugs used in anesthesia and surgery; opioids; non-targeted anti-cancer drugs; vaccines; and newly understood reaction mechanisms. This new edition includes photographs of a wide variety of cutaneous manifestations that will be of use to other clinicians as well as allergists and dermatologists. In addition to its wide clinical emphasis, the book’s mechanistic and structure-activity detail will provide valuable background for researchers and investigators in universities, medical research institutes, drug companies, and regulatory agencies. The second edition of Drug Allergy is an essential reference for practitioners across the medical disciplines from specialist clinicians, surgeons, GPs, residents, and medical students to nurses, pharmacists, dentists, and those taking undergraduate and graduate courses in the biomedical sciences.
- Contents
- 1. Scope of this Book: Adverse Reactions to Drugs and Drug Allergy -- 2. Classification and Descriptions of Allergic Reactions to Drugs -- 3. Mechanisms of Hypersensitivity -- 4. Diagnosis of Allergic Reactions to Drugs -- 5. ß-Lactam Antibiotics -- 6. Other Antimicrobial Drugs -- 7. Drugs and Other Agents Used in Anesthesia and Surgery -- 8. Opioid Analgesic Drugs -- 9. Non-steroidal Anti-inflammatory Drugs -- 10. Contrast Media -- 11. Corticosteroids -- 12. Proton Pump Inhibitors -- 13. Biologics: Monoclonal Antibodies for Non-cancer Therapy, Cytokines, Fusion Proteins, Enzymes, and Hormones -- 14. Targeted Drugs for Cancer Therapy: Small Molecules and Monoclonal Antibodies -- 15. Non-targeted Drugs for Cancer Therapy -- 16. Vaccines.
- Access
- NEW Springer 2021
- Format
- e-Book
- Location
- Online
Manual of Laparoscopic Urology
https://libcat.nshealth.ca/en/permalink/provcat28666
by Alberto Rosenblatt, Renaud Bollens, Baldo Espinoza Cohen.
--Berlin, Heidelberg:
Springer-Verlag
, c2008.
- Available Online
- View e-Book
- Location
- Online
- Available Online
- View e-Book
- Author
- Rosenblatt, Alberto
- Other Authors
- Bollens, Renaud
- Espinoza Cohen, Baldo
- Responsibility
- by Alberto Rosenblatt, Renaud Bollens, Baldo Espinoza Cohen
- Place of Publication
- Berlin, Heidelberg
- Publisher
- Springer-Verlag
- Date of Publication
- c2008
- ISBN
- 9783540747277
- Subjects (MeSH)
- Laparoscopy - methods
- Urologic Diseases - surgery
- Urologic Surgical Procedures - methods
- Urologic Surgical Procedures - Atlases
- Subjects (LCSH)
- Urology
- Endoscopic surgery
- Format
- e-Book
- Location
- Online
Safety of Biologics Therapy : Monoclonal Antibodies, Cytokines, Fusion Proteins, Hormones, Enzymes, Coagulation Proteins, Vaccines, Botulinum Toxins
https://libcat.nshealth.ca/en/permalink/provcat40166
Brian A. Baldo.
--Cham:
Springer
, c2016.
- Available Online
- View e-Book
- Location
- Online
This long overdue title provides a comprehensive, up-to-date, state-of-the art review of approved biologic therapies, with coverage of mechanisms of action, Indications for therapy, immunogenicity and a detailed examination of adverse effects and safety of the many and diverse therapeutic agents presented in a total of 13 chapters. It is predicted that by 2016, biologics will make up half of the world's 20 top-selling drugs and by 2018, biologic medicine sales will account for almost half of th…
- Available Online
- View e-Book
- Author
- Baldo, Brian A
- Responsibility
- Brian A. Baldo
- Place of Publication
- Cham
- Publisher
- Springer
- Date of Publication
- c2016
- Physical Description
- 1 online resource (xxi, 610 p. : 106 illus., 89 illus. in color)
- ISBN
- 9783319304724
- 9783319304700 (print ed.)
- Subjects (MeSH)
- Biological Products - therapeutic use
- Biological Therapy - methods
- Drug-Related Side Effects and Adverse Reactions - prevention & control
- Abstract
- This long overdue title provides a comprehensive, up-to-date, state-of-the art review of approved biologic therapies, with coverage of mechanisms of action, Indications for therapy, immunogenicity and a detailed examination of adverse effects and safety of the many and diverse therapeutic agents presented in a total of 13 chapters. It is predicted that by 2016, biologics will make up half of the world's 20 top-selling drugs and by 2018, biologic medicine sales will account for almost half of the world's 100 biggest selling drugs. Recombinant proteins dominate the growing list of the more than 200 approved biotherapeutic agents with targeted antibodies, fusion proteins and receptors; cytokines; hormones; enzymes; proteins involved in blood-clotting, homeostasis and thrombosis; vaccines; botulinum neurotoxins; and, more recently, biosimilar preparations, comprising the majority of approved biologics. Written with clinicians, other health care professionals, and researchers in mind, Safety of Biologics Therapy examines, in a single volume, the full range of issues surrounding the safety of approved biologic therapies. A good understanding of the risks and safety issues of modern biologics therapy is increasingly being demanded of all those connected with their development, handling, prescribing, administration and subsequent patient management. In addition to being of great value to clinicians in all branches of medicine, and to nurses, pharmacists and researchers, this book will prove invaluable for students taking undergraduate and graduate courses in the above disciplines and in the biomedical sciences.
- Contents
- 1. Approved Biologics Used For Therapy and their Adverse Effects -- 2. Monoclonal Antibodies: Introduction -- 3. Monoclonal Antibodies Approved for Cancer Therapy -- 4. Other Approved Therapeutic Monoclonal Antibodies -- 5. Cytokines -- 6. Fusion Proteins -- 7. Peptide Hormones -- 8. Glycoprotein Hormones -- 9. Enzymes Approved for Therapy -- 10. Blood Coagulation -- 11. Vaccines -- 12. Botulinum Neurotoxins -- 13. Biosimilars.
- Format
- e-Book
- Location
- Online
