Bernhard Gleich introduces Magnetic Particle Imaging (MPI) including all aspects that are necessary for a complete understanding. MPI is a new imaging modality invented by Bernhard Gleich and Jurgen Weizenecker. The method is capable of imaging the distribution of superparamagnetic iron oxide particles (SPIOs) with high sensitivity, high spatial resolution, and high imaging speed. The author summarizes the results of a number of original papers and countless innovations he has elaborated in the…
This book focuses on hormones, and on how they are produced in very diverse regions of the body in humans and animals. Hormones exhibiting the same synthesis pathways are not only found in vertebrates, but also in insects, shellfish, spiders, mollusks, and they were present evenat the time of metazoan diversification. The book discusses the different classes of hormones: protein/peptides hormones, steroids and juvenile hormones and hormones like catecholamines, thyroid hormones and melatonin. I…
This book provides a comprehensive up-to-date review of juvenile angiofibroma, with contributions from all relevant specialties. Starting with a brief introduction to the history, etiology and relevant anatomy, the book goes on to discuss the pathology, clinical features and treatment of this disease in depth, concluding with a summary of current controversies. Juvenile Angiofibroma is aimed at a global audience of otolaryngologists, endoscopists, head and neck surgeons, maxillofacial surgeons,…
This first of its kind richly illustrated book provides a tabular and schematic representation of all the peripheral nerves in the human body using a standardized landmark-based algorithm for the definition of the nerve’s “Point of optimal visibility (POV)”. In this atlas the nerves of the human body are depicted with high-frequent ultrasound probes with frequencies up to 24 MHz: it presents not only the “known” large nerves (N. ischiadicus, N. femoralis, N. medianus etc.), but also the tiny ne…
With the recent definition of the Th17 cell subset, a new paradigm in innate and adaptive immunity has been established. This book describes the function of the Th17 cell subset and its prevalent role in many inflammatory and autoimmune diseases. The mechanism by which this T cell subset is generated and maintained shows specific differences between mice and man which are reviewed. One characteristic of Th17 cells is to secrete specific and unique cytokines such as IL-17A, IL-17F and IL-22; the…
The knowledge of Th17 cells and other cell populations which secrete IL-17A, and/or IL-22 has expanded tremendously since the publication of the first edition "Th17 Cells: Role in Inflammation and Autoimmune Disease" in 2008. The present volume has been completely revised with the addition of new chapters on the IL-17 receptor family and signaling, and an in-depth review of IL-22 and innate lymphoid cells. The differentiation of naive T cells into regulatory T cells and Th17 cells as well as th…
The world is witnessing a burgeoning global epidemic of chronic cerebro- and cardiovascular disease and depression disorders. The reader will find this comprehensive book to be a long-needed, up-to-date knowledge base on these increasingly recognized comorbid conditions that have long-term consequences for individual function and well-being and society in general. This comprehensive book outlines the complex and bidirectional relationship between various types of depression and cerebro- and car…
This book presents the percutaneous techniques and technologies most frequently employed in structural interventional cardiology, focusing especially on how to optimize outcomes and minimize risk. Interventional procedures for aortic stenosis, mitral regurgitation, left atrial appendage closure, patent foramen ovale closure, and closure of interatrial and interventricular defects are clearly presented step by step with the aid of a wealth of images. These descriptions are complemented by a case…
This book covers the content of European postgraduate spine surgery courses, using a case-based approach. A step-wise solution to a real clinical problem is described and compared to the best available evidence. A weighted conclusion is provided on how to bridge the gap (if there is one) between standard of care and evidence-based medicine. Spine Surgery: A Case-Based Approach is aimed at postgraduate students of spine surgery (both trainee neurosurgeons and trainee orthopedic surgeons), and ma…
In our complex, fast changing society, health is strongly influenced by the continuously changing interactions between organisations and their employees. Three major fields contribute to health-oriented improvements of these interactions: occupational health, organizational health and public health. As currently only partial links exist amongst these fields, the book aims to explore potential synergies more systematically. Considering the high mental and social demands in a service and knowledg…
This book deals with neuroimaging of the brain, head, neck, and spine. During the last few years, there have been considerable advances in this subject, driven by clinical as well as technological developments. The authors, internationally renowned experts in their field, have contributed chapters that are diseaseoriented and cover all relevant imaging modalities, including magnetic resonance imaging, computed tomography, and positron emission tomography. As a result, this book offers a compreh…
Until a cure exists, Dupuytren's disease and related disorders such as Ledderhose's disease will pose lifelong threats of functional impairment for affected individuals. A better understanding of the onset of disease, early detection and functional preservation are of the utmost importance to minimize the impact of these conditions. This book is based on presentations and discussions at the 2010 International Symposium on Dupuytren's disease held in Miami, Florida, but it also includes new dat…