Preterm labour : managing risk in clinical practice
https://libcat.nshealth.ca/en/permalink/provcat27223
edited by Jane Norman, Ian Greer.
--Cambridge, UK:
Cambridge University Press
, 2005.
- Available Online
- View e-Book
- Location
- Online
- Available Online
- View e-Book
- Author
- Norman, Jane E
- Other Authors
- Greer, I. A
- Responsibility
- edited by Jane Norman, Ian Greer
- Alternate Title
- Preterm labor
- Place of Publication
- Cambridge, UK
- Publisher
- Cambridge University Press
- Date of Publication
- 2005
- Physical Description
- x, 417 p.
- ISBN
- 6610217963 (electronic bk.)
- Subjects (MeSH)
- Obstetric Labor, Premature
- Premature Birth
- Infant, Premature
- Contents
- Cover -- Half-title -- Title -- Copyright -- Table of Contents -- Contributors -- Preface -- 1 The epidemiology of preterm labour and delivery -- Defining the problem -- Definition of preterm delivery -- Determination of gestational age -- Incidence and secular trends -- Causes of preterm delivery -- Iatrogenic -- Idiopathic -- Infection -- Risk factors for preterm labour -- Maternal risk factors -- Summary -- References -- 2 Biology of preterm labour -- Introduction -- Myometrial contractions -- Organisation of myometrial smooth muscle -- Electrical activity -- Calcium and uterine contractions -- Control of myometrial function -- Cervical ripening -- Structure of the cervix -- The cervix during pregnancy -- Cervical ripening -- The control of cervical ripening -- Biology of membrane rupture -- Structure of fetal membranes -- Morphological changes associated with membrane rupture at term -- Biochemical events associated with membrane rupture at term -- Preterm premature rupture of the membranes (pPROM) -- Summary -- Biology of labour at term -- Role of infection -- Summary -- References -- 3 Transcriptional regulation of labour-associated genes -- Introduction -- Enzymes of the prostaglandin biosynthetic pathway -- PLA2 -- Cyclo-oxygenase (COX) -- Prostaglandin synthases -- Prostaglandin dehydrogenase -- Interleukin-8 -- Oxytocin Receptor -- Transcription factor activity and the onset of labour -- Cyclic AMP signalling -- Activator protein-1 and nuclear factor kappa B -- Steroid hormones -- Inhibition of NF-kappaB in the prevention of preterm delivery? -- References -- 4 Fetal outcome following preterm delivery -- Introduction -- Methodology of outcome reviews -- Description of immaturity -- Regional versus hospital-specific outcome -- Time period of study -- Denominator -- Age at death -- Growth restriction -- Multiple births -- Racial characteristics -- Lethal congenital malformations -- Follow-up compliance -- Mortality -- Major disabilities -- Overall severe disability -- Intellectual impairment -- Cerebral palsy (CP) -- Blindness -- Severe hearing impairment -- Short-term morbidity -- Chronic lung disease and home oxygen -- Retinopathy of prematurity -- Necrotising enterocolitis and feeding difficulties -- Rehospitalisation -- School age outcomes -- Chronic respiratory symptoms -- Dyspraxia -- Cognitive ability -- Behaviour -- Quality of life -- Growth -- Adolescent and adult outcomes -- Summary -- References -- 5 The prediction of preterm labour -- Risk scoring -- Cervical/vaginal secretions -- Fetal fibronectin -- Uterine activity monitoring -- Cervical ultrasound -- Endocrine factors -- Oestriol -- Corticotrophin-releasing hormone -- Relaxin -- Inflammatory cytokines -- Matrix metalloproteinase 9 (MMP-9) -- Other circulating factors -- Alpha-fetoprotein (AFP) --tidtid2179
- Format
- e-Book
- Location
- Online
The Histone Code and Beyond : New Approaches to Cancer Therapy
https://libcat.nshealth.ca/en/permalink/provcat40551
S.L. Berger, O. Nakanishi, B. Haendler, editors.
--Berlin, Heidelberg:
Springer Berlin Heidelberg
, c2006.
- Available Online
- View e-Book
- Location
- Online
Methylation of DNA at cytosine residues as well as post-translational modifications of histones, including phosphorylation, acetylation, methylation and ubiquitylation, contribute to the epigenetic information carried by chromatin. These changes play an important role in the regulation of gene expression by modulating the access of regulatory factors to the DNA. The use of a combination of biochemical, genetic and structural approaches has allowed demonstration of the role of chromatin structur…
- Available Online
- View e-Book
- Other Authors
- Berger, S. L
- Nakanishi, O
- Haendler, B
- Responsibility
- S.L. Berger, O. Nakanishi, B. Haendler, editors
- Place of Publication
- Berlin, Heidelberg
- Publisher
- Springer Berlin Heidelberg
- Date of Publication
- c2006
- Physical Description
- 1 online resource (xiv, 215 p.)
- Series Vol.
- 57
- Series Title
- Ernst Schering Research Foundation workshop
- ISBN
- 9783540376330
- 9783540278573 (print ed.)
- ISSN
- 0947-6075
- Subjects (MeSH)
- Histones
- Abstract
- Methylation of DNA at cytosine residues as well as post-translational modifications of histones, including phosphorylation, acetylation, methylation and ubiquitylation, contribute to the epigenetic information carried by chromatin. These changes play an important role in the regulation of gene expression by modulating the access of regulatory factors to the DNA. The use of a combination of biochemical, genetic and structural approaches has allowed demonstration of the role of chromatin structure in transcriptional control. The structure of nucleosomes has been elucidated and enzymes involved in DNA or histone modifications have been extensively characterized. Since deregulation of epigenetic marks has been reported in many cancers, a better understanding of the underlying molecular mechanisms bears the promise that new drug targets may soon be found. The newest developments in this quickly developing field are presented in this book.
- Contents
- The Role of Histone Modifications in Epigenetic Transitions During Normal and Perturbed Development -- Nucleosome Structure and Function -- The Role of Snf2-Related Proteins in Cancer -- Imitation Switch Complexes -- How Is Epigenetic Information on Chromatin Inherited After DNA Replication? -- Polycomb Silencing Mechanisms and Genomic Programming -- CpG Island Methylation and Histone Modifications: Biology and Clinical Significance -- Histone Post-Translational Modifications Regulate Transcription and Silent Chromatin in Saccharomyces Cerevisiae -- Histone Acetylation-Mediated Chromatin Compaction During Mouse Spermatogenesis -- Role of Ubiquitin-Like Proteins in Transcriptional Regulation -- Interplay of the SUMO and MAP Kinase Pathways.
- Format
- e-Book
- Publication Type
- Congress
- Location
- Online
A pharmacology primer : theory, applications, and methods
https://libcat.nshealth.ca/en/permalink/provcat27192
Terry Kenakin.
(2nd ed.)
--Burlington, MA:
Elsevier Academic Press
, c2006.
- Available Online
- View e-Book
- Location
- Online
- Available Online
- View e-Book
- Author
- Kenakin, Terrence P
- Responsibility
- Terry Kenakin
- Edition
- 2nd ed.
- Place of Publication
- Burlington, MA
- Publisher
- Elsevier Academic Press
- Date of Publication
- c2006
- Physical Description
- xviii, 299 p.
- ISBN
- 6610707650 (electronic bk.)
- 9786610707652 (electronic bk.)
- Subjects (MeSH)
- Dose-Response Relationship, Drug
- Pharmacology
- Pharmacokinetics
- Receptors, Drug - physiology
- Contents
- Cover -- Front cover -- Foreword to Second Edition -- Foreword to First Edition -- Table of Contents -- 1 What Is Pharmacology? -- 1.1 About This Book -- 1.2 What Is Pharmacology? -- 1.3 The Receptor Concept -- 1.4 Pharmacological Test Systems -- 1.5 The Nature of Drug Receptors -- 1.6 Pharmacological Intervention and the Therapeutic Landscape -- 1.7 System-independent Drug Parameters: Affinity and Efficacy -- 1.8 What Is Affinity? -- 1.9 The Langmuir Adsorption Isotherm -- 1.10 What Is Efficacy? -- 1.11 Dose-response Curves -- 1.12 Chapter Summary and Conclusions -- 1.13 Derivations: Conformational Selections as a Mechanism of Efficacy -- 2 How Different Tissues Process Drug Response -- 2.1 Drug Response as Seen Through the ''Cellular Veil'' -- 2.2 The Biochemical Nature of Stimulus-response Cascades -- 2.3 The Mathematical Approximation of Stimulus-response Mechanisms -- 2.4 System Effects on Agonist Response: Full and Partial Agonists -- 2.5 Differential Cellular Response to Receptor Stimulus -- 2.6 Receptor Desensitization and Tachyphylaxis -- 2.7 The Measurement of Drug Activity -- 2.8 Advantages and Disadvantages of Different Assay Formats -- 2.9 Drug Concentration as an Independent Variable -- 2.10 Chapter Summary and Conclusions -- 2.11 Derivations -- 3 Drug-Receptor Theory -- 3.1 About This Chapter -- 3.2 Drug-Receptor Theory -- 3.3 The Use of Mathematical Models in Pharmacology -- 3.4 Some Specific Uses of Models in Pharmacology -- 3.5 Classical Model of Receptor Function -- 3.6 The Operational Model of Receptor Function -- 3.7 Two-state Theory -- 3.8 The Ternary Complex Model -- 3.9 The Extended Ternary Model -- 3.10 Constitutive Receptor Activity -- 3.11 The Cubic Ternary Complex Model -- 3.12 Chapter Summary and Conclusions -- 3.13 Derivations -- 4 Pharmacological Assay Formats: Binding -- 4.1 The Structure of This Chapter -- 4.2 Binding Theory and Experiment -- 4.3 Complex Binding Phenomena: Agonist Affinity from Binding Curves -- 4.4 Experimental Prerequisites for Correct Application of Binding Techniques -- 4.5 Chapter Summary and Conclusions -- 4.6 Derivations -- 5 Agonists: The Measurement of Affinity and Efficacy in Functional Assays -- 5.1 Functional Pharmacological Experiments -- 5.2 The Choice of Functional Assays -- 5.3 Recombinant Functional Systems -- 5.4 Functional Experiments: Dissimulation in Time -- 5.5 Experiments in Real Time Versus Stop Time -- 5.6 The Measurement of Agonist Affinity in Functional Experiments -- 5.7 Estimates of Relative Efficacy of Agonists in Functional Experiments -- 5.8 Chapter Summary and Conclusions -- 5.9 Derivations -- 6 Orthosteric Drug Antagonism -- 6.1 Introduction -- 6.2 Kinetics of Drug-Receptor Interaction -- 6.3 Surmountable Competitive Antagonism -- 6.4 Noncompetitive Antagonism -- 6.5 Agonist-Antagonist Hemi-equilibria -- 6.6 Resultant Analysis -- 6.7 Chapter Summary and Conclusions -- 6.8 Derivations -- 7 Allosteric Drug Antagonism -- 7.1 Introduction -- 7.2 The Nature of Receptor Allosterism -- 7.3 Properties of Allosteric Modulators -- 7.4 Functional Study of Allosteric Modula
- Format
- e-Book
- Location
- Online
Textbook of neural repair and rehabilitation. Vol. I, Neural repair and plasticity
https://libcat.nshealth.ca/en/permalink/provcat27250
edited by Michael E. Selzer ... [et al.].
--Cambridge, UK:
Cambridge University Press
, c2006.
- Available Online
- View e-Book
- Location
- Online
- Available Online
- View e-Book
- Author
- Selzer, Michael E
- Responsibility
- edited by Michael E. Selzer ... [et al.]
- Place of Publication
- Cambridge, UK
- Publisher
- Cambridge University Press
- Date of Publication
- c2006
- ISBN
- 6610437238 (electronic bk.)
- Contents
- Cover -- Contents (contents of Volume I) -- Contents (contents of Volume II) -- Preface -- Contributors (contributors of Volume I) -- Contributors (contributors of Volume II) -- Neural repair and rehabilitation: an introduction -- 1 Definitions -- Neurorehabilitation -- Neuroplasticity -- Neural repair -- 2 History of neurorehabilitation as a medical subspecialty -- Origins of rehabilitation medicine -- 3 Outcomes measurement in rehabilitation medicine -- 4 Impact of evidence-based medicine on neurorehabilitation -- 5 Impact of the revolution in the science of neuroplasticity and regeneration on neurorehabilitation -- 6 Rehabilitation of cognitive functions -- 7 Purpose and organization of this book -- REFERENCES -- SECTION A: Neural plasticity -- SECTION A1: Cellular and molecular mechanisms of neural plasticity -- 1 Anatomical and biochemical plasticity of neurons: regenerative growth of axons, sprouting, pruning, and denervation supersensitivity -- 2 Learning and memory: basic principles and model systems -- 3 Short-term plasticity: facilitation and post-tetanic potentiation -- 4 Long-term potentiation and long-term depression -- 5 Cellular and molecular mechanisms of associative and nonassociative learning -- SECTION A2: Functional plasticity in CNS system -- 6 Plasticity of mature and developing somatosensory systems -- 7 Activity-dependent plasticity in the intact spinal cord -- 8 Plasticity of cerebral motor functions: implications for repair and rehabilitation -- 9 Plasticity in visual connections: retinal ganglion cell axonal development and regeneration -- 10 Plasticity in auditory functions -- 11 Cross-modal plasticity in sensory systems -- 12 Attentional modulation of cortical plasticity -- SECTION A3: Plasticity after injury to the CNS -- 13 Plasticity in the injured spinal cord -- 14 Plasticity after brain lesions -- 15 From bench to bedside: influence of theories of plasticity on human neurorehabilitation -- SECTION B: Neural repair -- SECTION B1: Basic cellular and molecular processes -- 16 Neuronal death and rescue: neurotrophic factors and anti-apoptotic mechanisms -- 17 Axon degeneration and rescue -- 18 Adult neurogenesis and neural precursors, progenitors, and stem cells in the adult CNS -- 19 Axon guidance during development and regeneration -- 20 Synaptogenesis -- SECTION B2: Determinants or regeneration in the injured nervous system -- 21 Inhibitors of axonal regeneration -- 22 Effects of the glial scar and extracellular matrix molecules on axon regeneration -- 23 Trophic factors and their influence on regeneration -- 24 Intraneuronal determinants of regeneration -- SECTION B3: Promotion of regeneration in the injured nervous system -- 25 Cellular replacement in spinal cord injury -- 26 Dysfunction and recovery in demyelinated and dysmyelinated axons -- 27 Role of Schwann cells in peripheral nerve regeneration -- 28 Transplantation of Schwann cells and olfactory ensheathing cells to promote regeneration in the CNS -- 29 Trophic factor delivery by gene therapy -- 30 Assessment of sensorimotor function after spinal cord injury and repair -- SECTION B4: Translational research: application to human neural injury -- 31 Alzheimer's disease, model systems and experimental therapeutics -- 32 Biomimetic design of neural prostheses -- 33 Brain...compute
- Format
- e-Book
- Location
- Online
Thompson & Thompson genetics in medicine
https://libcat.nshealth.ca/en/permalink/provcat31481
Robert L. Nussbaum, Roderick R. McInnes, Huntington F. Willard ; with clinical case studies updated and new cases prepared by Ada Hamosh.
(7th ed.)
--Philadelphia, PA:
Saunders/Elsevier
, c2007.
- Available Online
- View e-Book
- Access
- Registration required for PDF access.
- Location
- Online
Through six editions, Thompson & Thompson's Genetics in Medicine has been a well-established favorite textbook on this fascinating and rapidly evolving field, integrating the classic principles of human genetics with modern molecular genetics to help you understand a wide range of genetic disorders. The 7th edition incorporates the latest advances in molecular diagnostics, the Human Genome Project, and much more. More than 240 dynamic illustrations and high-quality photos help you grasp complex…
- Available Online
- View e-Book
- Author
- Nussbaum, Robert L
- Responsibility
- Robert L. Nussbaum, Roderick R. McInnes, Huntington F. Willard ; with clinical case studies updated and new cases prepared by Ada Hamosh
- Edition
- 7th ed.
- Alternate Title
- Genetics in medicine
- Thompson and Thompson genetics in medicine
- Place of Publication
- Philadelphia, PA
- Publisher
- Saunders/Elsevier
- Date of Publication
- c2007
- Physical Description
- 1 online resource (xi, 585 p.)
- ISBN
- 9781416030805 (electronic bk.)
- Subjects (MeSH)
- Genetics, Medical
- Pathology, Molecular
- Subjects (LCSH)
- Medical genetics
- Genetics, Medical
- Abstract
- Through six editions, Thompson & Thompson's Genetics in Medicine has been a well-established favorite textbook on this fascinating and rapidly evolving field, integrating the classic principles of human genetics with modern molecular genetics to help you understand a wide range of genetic disorders. The 7th edition incorporates the latest advances in molecular diagnostics, the Human Genome Project, and much more. More than 240 dynamic illustrations and high-quality photos help you grasp complex concepts more easily. In addition to the book, you will also receive STUDENT CONSULT, enabling you to access the complete contents of the book online, anywhere you go! Acquire the state-of-the-art knowledge you need on the latest advances in molecular diagnostics, the Human Genome Project, pharmacogenetics, and bio-informatics. Better understand the relationship between basic genetics and clinical medicine with a variety of clinical case studies. Recognize a wide range of genetic disorders with visual guidance from more than 240 dynamic illustrations and high-quality photos. Access the complete contents of the book online, fully searchable with STUDENT CONSULT. You'll find "Integration Links" to bonus content in other STUDENT CONSULT titles content clipping for handheld devices an interactive community center with a wealth of additional resources quarterly updates on the material USMLE questions and much more.
- Contents
- Introduction -- 1. Chromosomal Basis of Heredity -- 2. The Human Genome: Structure and Function of Genes and Chromosomes -- 3. Tools of Human Molecular Genetics -- 4. Principles of (Clinical) Cytogenetics -- 5. Clinical Cytogenetics: Disorders of the Autosomes and the Sex Chromosomes -- 6. Mechanisms of Inheritance part I: Mendelian (or Single-Gene) Patterns -- 7. Mechanisms of Inheritance part II: Mitochondrial, Imprinted, and Multifactorial Patterns -- 8. Genetic Variation in Individuals and Populations -- 9. The Genetic Contribution to Disease: Locating and identifying Disease Genes -- 10. Principles of Molecular Disease: Lessons from the Hemoglobinopathies -- 11. The Molecular and Biochemical Basis of Genetic Disease -- 12. The Treatment of Genetic Disease -- 13. Developmental Disorders and Birth Defects (Leslie Biesecker) -- 14. Genetics of Cancer -- 15. Genetic Counseling and Risk Assessment -- 16. Molecular Diagnostics -- 17. Prenatal Diagnosis -- 18. Genetics and Society -- Case Studies.
- Access
- Registration required for PDF access.
- Format
- e-Book
- Location
- Online
Abeta Peptide and Alzheimer's Disease : Celebrating a Century of Research
https://libcat.nshealth.ca/en/permalink/provcat40582
Colin J. Barrow and David H. Small (eds.).
--London:
Springer
, c2007.
- Available Online
- View e-Book
- Location
- Online
Abeta Peptide and Alzheimer's Disease summarizes current knowledge of beta-amyloid peptide (Aß) and its role as the major culprit in Alzheimer's Disease (AD), shown by recent advances in genetics and brain biochemistry. Written by leaders in the industrial and academic world specializing in this rapidly moving area, the book covers fundamental biochemical studies on the Aß peptide, the genetic impact on Aß expression and processing, and various AD therapeutic strategies that target Aß. Although…
- Available Online
- View e-Book
- Other Authors
- Barrow, Colin J
- Small, David H
- Responsibility
- Colin J. Barrow and David H. Small (eds.)
- Place of Publication
- London
- Publisher
- Springer
- Date of Publication
- c2007
- Physical Description
- 1 online resource (xi, 298 p.)
- ISBN
- 9781846284403
- 9781852339616 (print ed.)
- Subjects (MeSH)
- Alzheimer Disease - etiology
- Alzheimer Disease - metabolism
- Amyloid beta-Peptides - metabolism
- Abstract
- Abeta Peptide and Alzheimer's Disease summarizes current knowledge of beta-amyloid peptide (Aß) and its role as the major culprit in Alzheimer's Disease (AD), shown by recent advances in genetics and brain biochemistry. Written by leaders in the industrial and academic world specializing in this rapidly moving area, the book covers fundamental biochemical studies on the Aß peptide, the genetic impact on Aß expression and processing, and various AD therapeutic strategies that target Aß. Although specifically focusing on Aß and AD, there is also some discussion on the similarity and differences of this peptide and AD with other amyloidogenic diseases, such as prion disease, Parkinson's and Huntington's. This book will primarily be of interest to AD researchers and clinicians but also to researchers of other amyloid diseases.
- Contents
- A Brief Introduction to the History of the ß-Amyloid Protein (Aß) of Alzheimer’s Disease -- The Aßcentric Pathway of Alzheimer's Disease -- The Function of the Amyloid Precursor Protein Family -- The Involvement of Aß in the Neuroinflammatory Response -- Amyloid ß-Peptide(1-42), Oxidative Stress, and Alzheimer's Disease -- Amyloid Toxicity, Synaptic Dysfunction, and the Biochemistry of Neurodegeneration in Alzheimer's Disease -- Aß Variants and Their Impact on Amyloid Formation and Alzheimer's Disease Progression -- Copper Coordination by ß-Amyloid and the Neuropathology of Alzheimer's Disease -- Cholesterol and Alzheimer's Disease -- Amyloid ß-Peptide and Central Cholinergic Neurons: Involvement in Normal Brain Function and Alzheimer's Disease Pathology -- Physiologic and Neurotoxic Properties of Aß Peptides -- Impact of ß-Amyloid on the Tau Pathology in Tau Transgenic Mouse and Tissue Culture Models -- Glial Cells and Aß Peptides in Alzheimer's Disease Pathogenesis -- The Role of Presenilins in Aß-Induced Cell Death in Alzheimer's Disease -- Immunotherapeutic Approaches to Alzheimer's Disease -- Mouse Models of Alzheimer's Disease.
- Format
- e-Book
- Location
- Online
Post-genomic cardiology
https://libcat.nshealth.ca/en/permalink/provcat27609
Marin-Garcia, Jose.
--Amsterdam, Netherlands:
Elsevier Academic Press
, 2007.
- Available Online
- View e-Book
- Location
- Online
- Available Online
- View e-Book
- Author
- Marin-Garcia, Jose
- Other Authors
- Goldenthal, Michael J
- Moe, Gordon W
- Place of Publication
- Amsterdam, Netherlands
- Publisher
- Elsevier Academic Press
- Date of Publication
- 2007
- Physical Description
- 688 p.
- ISBN
- 9780080554549
- Subjects (MeSH)
- Cardiovascular Diseases - genetics
- Contents
- Introduction to post-genomic cardiology -- Molecular and biochemical methodology in the post-genomic era -- Cardiovascular gene expression -- Cellular techniques -- Cardiovascular signaling pathways -- Cardiac development: molecular and genetic analysis -- Congenital and acquired heart disease -- Molecular basis of lipoprotein disorders, atherogenesis, and thrombosis -- Ischemia and myocardial infarction: a post-genomic analysis -- Cellular pathways and molecular events in cardioprotection -- Cardiac neovascularization: angiogenesis, arteriogenesis and vasculogenesis -- Systemic and pulmonary hypertension -- Cardiomyopathies -- Heart response to inflammation and infection -- Molecular analysis of heart failure and remodeling -- Fatty acid and glucose metabolism in cardiac disease -- Dysrhythmias and sudden death -- Gender and cardiovascular disease -- The aging heart: a post-genomic appraisal -- Future of post-genomic cardiology.
- Format
- e-Book
- Location
- Online
The Paraoxonases : Their Role in Disease Development and Xenobiotic Metabolism
https://libcat.nshealth.ca/en/permalink/provcat40620
edited by Bharti Mackness, Mike Mackness, Michael Aviram and György Paragh.
--Dordrecht:
Springer
, c2008.
- Available Online
- View e-Book
- Location
- Online
Research into the paraoxonase (PON) multigene family has really only blossomed in the last 10 years. Before this time only PON1 was known and research was restricted to toxicologists investigating the metabolism of organophosphate insecticides and nerve gases and a few "mad" scientists searching for "natural" substrates. Since this time two new members PON2 and PON3 have been discovered, all 3 PONs have been shown to act as antioxidants and the PON family has taken centre stage as major players…
- Available Online
- View e-Book
- Other Authors
- Mackness, Bharti
- Mackness, Mike
- Aviram, Michael
- Paragh, György
- Responsibility
- edited by Bharti Mackness, Mike Mackness, Michael Aviram and György Paragh
- Place of Publication
- Dordrecht
- Publisher
- Springer
- Date of Publication
- c2008
- Physical Description
- 1 online resource (xv, 323 p. : ill.)
- Series Vol.
- v. 6
- Series Title
- Proteins And Cell Regulation
- ISBN
- 9781402065613
- 9781402065606 (print ed.)
- Subjects (MeSH)
- Aryldialkylphosphatase
- Abstract
- Research into the paraoxonase (PON) multigene family has really only blossomed in the last 10 years. Before this time only PON1 was known and research was restricted to toxicologists investigating the metabolism of organophosphate insecticides and nerve gases and a few "mad" scientists searching for "natural" substrates. Since this time two new members PON2 and PON3 have been discovered, all 3 PONs have been shown to act as antioxidants and the PON family has taken centre stage as major players in the development of a wide variety of diseases such as cardiovascular disease, diabetes mellitus, rheumatism, Alzheimer and many more while remaining important in determining organophosphate toxicity. In September 2006 the 2nd International Conference on Paraoxonases took place in Hajdúszoboszló, Hungary, bringing together the world's foremost experts in the field. The current book is a distillation of the plenary lectures which took place at the meeting, resulting in a comprehensive up to date, state of the art review of current paraoxonase research.
- Contents
- Part 1. The Bert La Du Memorial Lecture -- Paraoxonases: An Historical Perspective -- Part 2. PONs and Atherosclerosis -- Glucose Inactivates Paraoxonase 1 (PON1) and Displaces it from High Density Lipoprotein (HDL) to a Free PON1 Form -- Paraoxonase-1 and Cardiovascular Disease -- Oxidative Stress & Antioxidants and PON1 in Health and Disease -- D-4F Increases Paraoxonase 1 Activity in HDL -- Paraoxonase 1 (PON1), A Junction Between the Metabolisms of Homocysteine and Lipids -- The Role of PON2 and PON3 in Atherosclerosis and Related Traits -- Paraoxonase 1 and Postprandial Lipemia -- PON1 Genotypes and Coronary Heart Disease -- Part 3. PON1 Structure -- Human Paraoxonase I: A Potential Bioscavenger of Organophosphorus Nerve Agents -- Stabilisation of Active Form of Natural Human PON1 Requires HPBP -- Part 4. PONs in Disease other than Atherosclerosis -- Paraoxonase-1 in Chronic Liver Diseases, Neurological Diseases and HIV Infection -- Age-Related Alterations in PON1 -- Part 5. PON and Toxicology -- Paraoxonase (PON1) and Organophosphate Toxicity -- Implications of Paraoxonase-1 (PON1) Activity and Polymorphisms on Biochemical and Clinical Outcomes in Workers Exposed to Pesticides -- Part 6. PON-Genetics and Regulation -- Transcriptional Regulation of the Paraoxonase Genes -- Effect of Lipid Lowering Medications on PON1 -- The Functional Consequences of Polymorphisms in the Human PON1 Gene -- Dietary Modulation of Paraoxonase-1 Activity and Concentration in Humans -- Part 7. PONs Biochemistry -- PONs' Natural Substrates: The Key for their Physiological Roles -- Paraoxonases, Quorum Sensing, And Pseudomonas Aeruginosa.
- Format
- e-Book
- Publication Type
- Congress
- Location
- Online
Insulin Resistance : Childhood Precursors and Adult Disease
https://libcat.nshealth.ca/en/permalink/provcat40633
Philip Scott Zeitler, Kristen J. Nadeau, editors.
--Totowa, NJ:
Humana Press
, c2008.
- Available Online
- View e-Book
- Location
- Online
The prevalence of disorders related to insulin resistance has continued to increase throughout the developed and developing world. The world's population has continued to become more obese and sedentary. Of great concern in the last decade is the extension of these deleterious lifestyle patterns to the pediatric population, leading to both obesity and the appearance of insulin resistance-related disorders in youth as well as adults. Insulin Resistance: Childhood Precursors and Adult Disease pre…
- Available Online
- View e-Book
- Other Authors
- Zeitler, Philip Scott, 1957-
- Nadeau, Kristen J
- Responsibility
- Philip Scott Zeitler, Kristen J. Nadeau, editors
- Place of Publication
- Totowa, NJ
- Publisher
- Humana Press
- Date of Publication
- c2008
- Physical Description
- 1 online resource (xi, 331 p. : [8] p. of plates : ill.)
- Series Title
- Contemporary endocrinology
- ISBN
- 9781597451925
- 9781588298751 (print ed.)
- Subjects (MeSH)
- Insulin Resistance
- Abstract
- The prevalence of disorders related to insulin resistance has continued to increase throughout the developed and developing world. The world's population has continued to become more obese and sedentary. Of great concern in the last decade is the extension of these deleterious lifestyle patterns to the pediatric population, leading to both obesity and the appearance of insulin resistance-related disorders in youth as well as adults. Insulin Resistance: Childhood Precursors and Adult Disease presents topics related to insulin resistance and its consequences across the lifespan. In the first section of the book examining epidemiology, the contributors review controversies over the definition of metabolic syndrome in adults and children, current knowledge regarding the epidemiology of insulin resistance in the pediatric population and the contributions of the prenatal and early childhood environment to the development of insulin resistance. The Second part of the book explores pathophysiology, with reviews of the techniques used to study insulin resistance, as well as current knowledge of the molecular and physiologic mechanisms of insulin resistance, including the contributions of adipose tissue and biochemical mediators. This section concludes with discussion of the relationship between insulin resistance and cardiovascular, endothelial, liver and gonadal disorders. The final section of the book explores the impact of exercise and weight loss medications on insulin resistance. Insulin resistance is likely to be the most important public health concern in many parts of the world in coming decades. This volume provides up-to-date reviews of these areas, providing the reader with a current perspective on issues in insulin resistance as they affect patients across the lifespan. The hope for Insulin Resistance: Childhood Precursors and Adult Disease is that it will spur continued interest in the topic on the part of clinicians and researchers, perhaps promoting new points of view and creative approaches to a daunting challenge.
- Contents
- Part I. Epidemiology -- The Metabolic Syndrome: Definitions, Controversies and Clinical Utility -- Epidemiology of the Metabolic Syndrome and Related Disorders in Children and Adolescents -- Metabolic Syndrome in Children and Adolescents Worldwide -- Maternal-Fetal Contributors to the Insulin Resistance Syndrome in Youth -- Early Childhood Contributions to Insulin Resistance -- Part II. Pathophysiology -- Molecular Mechanisms of Insulin Resistance -- Techniques Used to Assess Insulin Action -- Adiposity is The Enemy: Body Composition and Insulin Sensitivity -- Ectopic Fat Deposition, Adiponectin and Insulin Resistance in Obese Adolescents -- Mediators of Insulin Resistance -- Insulin Resistance and the Pathogenesis of Cardiovascular Disease -- Insulin Resistance and Cardiovascular Disease -- The Liver and Insulin Resistance: The Important Convergence of Endocrinology and Hepatology -- Polycystic Ovary Syndrome and Metabolic Syndrome -- Part III. Treatment -- Effects of Exercise in Metabolic Syndrome and Diabetes: A Central Role for Insulin Sensitivity -- Weight Loss Medications and the Metabolic Syndrome.
- Format
- e-Book
- Location
- Online
Laboratory Guide to the Methods in Biochemical Genetics
https://libcat.nshealth.ca/en/permalink/provcat28397
edited by Nenad Blau, Marinius Duran, K. Michael Gibson.
--Berlin, Heidelberg:
Springer-Verlag
, c2008.
- Available Online
- View e-Book
- Location
- Online
- Available Online
- View e-Book
- Author
- Blau, Nenad
- Other Authors
- Duran, Marinius
- Gibson, K. Michael
- Responsibility
- edited by Nenad Blau, Marinius Duran, K. Michael Gibson
- Place of Publication
- Berlin, Heidelberg
- Publisher
- Springer-Verlag
- Date of Publication
- c2008
- ISBN
- 9783540766988
- Subjects (MeSH)
- Metabolism, Inborn Errors - diagnosis - Laboratory Manuals
- Molecular Biology - methods - Laboratory Manuals
- Subjects (LCSH)
- Genetics
- Medical laboratories
- Biochemistry
- Format
- e-Book
- Location
- Online
Integrative Pain Medicine : The Science and Practice of Complementary and Alternative Medicine in Pain Management
https://libcat.nshealth.ca/en/permalink/provcat29487
edited by Joseph F. Audette, Allison Bailey.
--Totowa, NJ:
Humana Press
, c2008.
- Available Online
- View e-Book
- Location
- Online
- Available Online
- View e-Book
- Author
- Audette, Joseph F
- Other Authors
- Bailey, Allison
- Responsibility
- edited by Joseph F. Audette, Allison Bailey
- Place of Publication
- Totowa, NJ
- Publisher
- Humana Press
- Date of Publication
- c2008
- Series Title
- Contemporary Pain Medicine
- ISBN
- 9781597453448
- Subjects (MeSH)
- Pain Management - methods
- Complementary Therapies
- Subjects (LCSH)
- Pain medicine
- Alternative medicine
- Contents
- Pt. I. Introduction -- 1. Legal and Ethical Issues in Integrative Pain Management / Michael H. Cohen -- Pt. II. Future Trends in CAM Research -- 2. Basic Mechanisms of Pain / Frank Willard -- 3. Functional Neuroanatomy of Pain Perception / Norman W. Kettner -- 4. Neuroimaging for the Evaluation of CAM Mechanisms / Vitaly Napadow, Rupali P. Dhond and Norman W. Kettner -- 5. Integrating Dry Needling with New Concepts of Myofascial Pain, Muscle Physiology, and Sensitization / Jay P. Shah -- 6. Potential Role of Fascia in Chronic Musculoskeletal Pain / Helene M. Langevin -- 7. Biochemical and Nutritional Influences on Pain / Steve Parcell -- 8. Exercise Testing and Training in Patients with (Chronic) Pain / Harriet Wittink and Tim Takken -- Pt. III. Therapeutic Techniques -- 9. Meditation and Chronic Pain / Joshua Wootton -- 10. Adjunctive Hypnotic Management of Acute Pain in Invasive Medical Interventions / Gloria Maria Martinez Salazar, Salomao Faintuch and Elvira V. Lang -- 11. Energy-Based Therapies for Chronic Pain / Eric Leskowitz -- 12. Tai Chi in Pain Medicine / Joseph F. Audette -- 13. Yoga in Pain Management / Loren Fishman and Ellen Saltonstall -- 14. Contemporary Aquatic Therapy and Pain Management / Douglas W. Kinnaird and Bruce E. Becker -- 15. Osteopathic Medicine in Chronic Pain / James H. Gronemeyer and Alexios G. Carayannopoulos -- 16. Chiropractic Pain Management: An Integrative Approach / Norman W. Kettner -- 17. Therapeutic Massage and Bodywork in Integrative Pain Management / Arthur Madore and Janet R. Kahn -- 18. Acupuncture in Pain Management / David Wang and Joseph F. Audette -- 19. Nutrition and Supplements for Pain Management / Maria Sulindro-Ma, Charise L. Ivy and Amber C. Isenhart -- 20. Botanicals in the Management of Pain / Tieraona Low Dog -- 21. Chinese Herbal Medicine for Pain / David Euler -- Pt. IV. Integrative Models -- 22. Integrative Pain Medicine Models: Women’s Health Programs / Allison Bailey and Meryl Stein -- 23. Integrative Medicine: History, Overview, and Applications to Pain Management / Joseph Mosquera.
- Format
- e-Book
- Location
- Online
The Local Cardiac Renin-Angiotensin Aldosterone System
https://libcat.nshealth.ca/en/permalink/provcat29683
Edward D. Frohlich, Richard N. Re, editors.
(2nd ed.)
--Boston, MA:
Springer-Verlag US
, c2009.
- Available Online
- View e-Book
- Location
- Online
How exciting it is to see a field so well established as the ren- angiotensin system continue to grow and mature. Originally, following the original identification of renin by Tigerstedt and Bergman over 100 years ago, workers in this area spent years attempting to establish its role in experimental and renal hypertension. The early work by Goldblatt, in 1934, demonstrated that the placement of a clip around a renal artery was clearly related to the subsequent development of hypertension. Howev…
- Available Online
- View e-Book
- Author
- Frohlich, Edward D
- Other Authors
- International Workshop on the Local Cardiac Renin Angiotensin Aldosterone System (3rd : 2008 : New Orleans, La.)
- Other Authors
- Re, Richard N
- Responsibility
- Edward D. Frohlich, Richard N. Re, editors
- Edition
- 2nd ed.
- Place of Publication
- Boston, MA
- Publisher
- Springer-Verlag US
- Date of Publication
- c2009
- ISBN
- 9781441905284
- Subjects (MeSH)
- Cardiology - Congresses
- Hypertension - metabolism
- Receptors, Cell Surface - physiology
- Renin-Angiotensin System - physiology
- Vacuolar Proton-Translocating ATPases - metabolism
- Subjects (LCSH)
- Cardiology
- Physiology
- Abstract
- How exciting it is to see a field so well established as the ren- angiotensin system continue to grow and mature. Originally, following the original identification of renin by Tigerstedt and Bergman over 100 years ago, workers in this area spent years attempting to establish its role in experimental and renal hypertension. The early work by Goldblatt, in 1934, demonstrated that the placement of a clip around a renal artery was clearly related to the subsequent development of hypertension. However, it wasn't until the simultaneous finding by two different geographically separated teams, Page, et al, in the United States and Braun-Menendez, et al, in Argentina that the peptide angiotensin was identified. Thus, the rate-limiting enzyme renin was released from the kidney and catalyzed a biochemical cascade which was eventually shown to produce the elevated arterial pressure. Subsequently, many workers contributed to the elucidation of the concept and sequence of angiotensin I1 generation. Thus, the enzyme renin acted upon its protein substrate, produced in the liver, to liberate the decapeptide angiotensin I which, upon circulating through the pulmonary circulation, finally produced the potent octapeptide angiotensin. Several important subsequent findings demonstrated that angiotensin I1 promoted the release of the adrenal corticosteroid from that gland, thereby resulting in a larger system, the renin-angiotensin-aldosterone system. Further, this system demonstrated a classical biofeedback and the circulating octapeptide was shown to have additional biological activities in organs other than heart, vessels, kidney, adrenals, and even brain.
- Contents
- 1. Are Local Renin–Angiotensin Systems the Focal Points for Understanding Salt Sensitivity in Hypertension? -- 2. Newer Insights into the Biochemical Physiology of the Renin–Angiotensin System: Role of Angiotensin-(1-7), Angiotensin Converting Enzyme 2, and Angiotensin-(1-12) -- 3. Renin, Prorenin, and the (Pro)renin Receptor -- 4. Intracellular Accumulation and Nuclear Trafficking of Angiotensin II and the Angiotensin II Type 1 Receptor -- 5. Pathophysiologic Implications of Cell Swelling in the Failing Heart: Influence of Intracrine and Extracellular Renin–Angiotensin Systems -- 6. Exploiting Rat Genetics to Investigate Hypertensive End-Organ Damage -- 7. Alternative Renin Transcripts and Functions of Cytoplasmatic Renin -- 8. Novel Aspects of the Cardiac Renin–Angiotensin System -- 9. Intracrine Function from Angiotensin to Stem Cells -- 10. Renin Cell Identity and Homeostasis -- 11. Role of Renal Aminopeptidases and Angiotensin Type-2 (AT2) Receptors in Sodium Excretion and Hypertension -- 12. Intrarenal Angiotensin II Augmentation in Hypertension -- 13. Collecting Duct Renin: A Critical Link in Angiotensin II-Dependent Hypertension -- 14. Renin–Angiotensin–Aldosterone System and Cardiomyocyte Apoptosis in Hypertensive Heart Disease -- 15. Upregulation of Angiotensin II Type 2 Receptor (agtr2) Attenuates Atherosclerotic Lesion Formation and Enhances Apoptosis in the LDL Receptor Knockout Mice Fed High Cholesterol Diet -- 16. Salt and Heart: RAAS Involvement -- 17. Cardiac Effects of Aldosterone, the Bad, but Is There Also a Good?
- Format
- e-Book
- Location
- Online
Ocular disease : mechanisms and management
https://libcat.nshealth.ca/en/permalink/provcat31547
[edited by] Leonard A. Levin, Daniel M. Albert.
--[Philadelphia]:
Saunders/Elsevier
, 2010.
- Available Online
- View e-Book
- Access
- Registration required for PDF access.
- Location
- Online
Ocular Disease-a newly introduced companion volume to the classic Adlers Physiology of the Eye-correlates basic science and clinical management to describe the how and why of eye disease processes and the related best management protocols. Editors Leonard A. Levin and Daniel M. Albert-two of the world's leading ophthalmic clinician-scientists-have recruited as contributors the most expert and experienced authorities available in each of the major areas of ophthalmic disease specific to ophthalm…
- Available Online
- View e-Book
- Other Authors
- Levin, Leonard A
- Albert, Daniel M
- Responsibility
- [edited by] Leonard A. Levin, Daniel M. Albert
- Place of Publication
- [Philadelphia]
- Publisher
- Saunders/Elsevier
- Date of Publication
- 2010
- Physical Description
- 1 online resource (xv, 687 p.)
- ISBN
- 9780702029837
- Subjects (MeSH)
- Eye Diseases
- Eye - physiopathology
- Subjects (LCSH)
- Ophthalmology
- Eye - Diseases
- Eye - Diseases - Treatment
- Eye Diseases
- Eye - physiopathology
- Ophtalmologie
- Œil - Maladies
- Œil - Maladies - Traitement
- Notes
- "Expert consult"--Cover
- Abstract
- Ocular Disease-a newly introduced companion volume to the classic Adlers Physiology of the Eye-correlates basic science and clinical management to describe the how and why of eye disease processes and the related best management protocols. Editors Leonard A. Levin and Daniel M. Albert-two of the world's leading ophthalmic clinician-scientists-have recruited as contributors the most expert and experienced authorities available in each of the major areas of ophthalmic disease specific to ophthalmology: retina, cornea, cataract, glaucoma, uveitis, and more. The concise chapter structure features liberal use of color-with 330 full-color line artworks, call-out boxes, summaries, and schematics for easy navigation and understanding. In print and online at expertconsult.com, this comprehensive resource provides you with a better and more practical understanding of the science behind eye disease and its relation to treatment. Includes access to the fully searchable text online at expertconsult.com, along with images and references. Covers all areas of disease in ophthalmology including retina, cornea, cataract, glaucoma, and uveitis for the comprehensive information you need for managing clinical cases. Presents a unique and pragmatic blend of necessary basic science and clinical application to serve as a clinical guide to understanding the cause and rational management of ocular disease
- Contents
- Loss of corneal transparency / Russell L McCally -- Abnormalities of corneal wound healing / Audrey M Bernstein -- Wound healing after laser in situ keratomileusis and photorefractive keratectomy / Fabricio Witzel de Medeiros and Steven E Wilson -- Genetics and mechanisms of hereditary corneal dystrophies / John D Gottsch -- Fuchs' endothelial corneal dystrophy / Vinay Gutti, David S Bardenstein, Sudha Iyengar, and Jonathan H Lass -- Keratoconus / M Cristina Kenney and Ronald N Gaster -- Infectious keratitis / Michael S Gilmore, Susan R Heimer, and Ai Yamada -- Corneal graft rejection / Daniel R Saban, Mohammad H Dastjerdi, and Reza Dana -- Corneal edema / Daniel G Dawson and Henry F Edelhauser -- Corneal angiogenesis and lymphangiogenesis / Chih-Wei Wu, David Ellenberg, and Jin-Hong Chang -- Ocular surface restoration / Julie T Daniels, Genevieve A Secker, and Alex J Shortt -- Herpetic keratitis / Pranita P Sarangi and Barry T Rouse -- Ocular allergy / Neal P Barney, Ellen B Cook, James L Stahl, and Frank M Graziano -- The lacrimal gland and dry-eye disease / Darlene A Dartt -- Immune mechanisms of dry-eye disease / Austin K Mircheff and Joel E Schechter -- Disruption of tear film and blink dynamics / Jianhua Wang and Anuj Chauhan -- Abnormalities of eyelid and tear film lipid / Gary N Foulks and Douglas Borchman -- Dry eye: abnormalities of tear film mucins / Ann-Christin Albertsmeyer and Ilene K Gipson -- Steroid-induced glaucoma / Abbot F Clark, Xinyu Zhang, and Thomas Yorio -- Biomechanical changes of the optic disc / Ian A Sigal, Michael D Roberts, Michael JA Girard, Claude F Burgoyne, and J Crawford Downs -- Pigmentary dispersion syndrome and glaucoma / Michael G Anderson -- Abnormal trabecular meshwork outflow / Paul A Knepper and Beatrice YJT Yue -- Pressure-induced optic nerve damage / James C Tsai -- Exfoliation (pseudoexfoliation) syndrome / Robert Ritch and Ursula Schultzer-Schrehardt -- Angle closure glaucoma / Shamira Perera, Nishani Amerasinghe, and Tin Aung -- Central nervous system changes in glaucoma / Yeni N Yücel and Neeru Gupta -- Retinal ganglion cell death in glaucoma / Heather R Pelzel and Robert W Nickells -- Wound-healing responses to glaucoma surgery / Stelios Georgoulas, Annegret Dahlmann-Noor, Stephen Brocchini, and Peng Tee Khaw -- Blood flowchanges in glaucoma / Leopold Schmetterer and Mark Lesk -- Biochemical mechanisms of age-related cataract / David C Beebe, Ying-Bo Shui, and Nancy M Holekamp -- Posterior capsule opacification / Judith West-Mays and Heather Sheardown -- Diabetes-associated cataracts / Peter F Kador -- Steroid-induced cataract / Abbas Samadi -- Presbyopia / Jane F Koretz -- Restoration of accommodation / Stephen D McLeod and Michelle Trager Cabrera -- Intraoperative floppy iris syndrome / Amy Lin and Roger F Steinert -- Optic neuritis / John R Guy and Xiaoping Qi -- Abnormal ocular motor control / James A Sharpe and Arun Sundaram -- Idiopathic intracranial hypertension (idiopathic pseudotumor cerebri) / Deborah M Grzybowski and Martin Lubow -- Giant cell arteritis / Lynn K Gordon -- Ischemic optic neuropathy / Helen Danesh-Meyer -- Optic nerve axonal injury / Daniela Toffoli and Leonard A Levin -- Leber's hereditary optic neuropathy / Alfredo Sadun and Alice Kim -- Optic atrophy / Nathan T Tagg and Randy H Kardon -- Nystagmus / Frank Proudlock and Irene Gottlob -- Toxic optic nerve neuropathies / FT "Fritz" Fraunfelder and FW "Rick" Fraunfelder -- Uveal melanoma / Zelia MS Correa and J William Harbour -- Genetics of hereditary retinoblastoma / Alejandra G de Alba Campomanes and Joan M O'Brien -- Molecular basis of low-penetrance retinoblastoma / Katie Matatall and J William Harbour -- Vasculogenic mimicry / Robert Folberg and Andrew J Maniotis -- Treatment of choroidal melanoma / Aimee V Chappelow and Andrew P Schachat -- Sebaceous cell carcinoma / Alon Kahana, Jonathan T Pribila, Christine C Nelson, and Victor M Elner -- Neurofibromatosis / Robert Listernick and David H Gutmann -- Phthisis bulbi / Ingo Schmack, Hans E Volcker, and Hans E Grossniklaus -- Myopia / Terri L Young -- Pathogenesis of Graves' ophthalmopathy / A Reagan Schiefer and Rebecca S Bahn -- Duane syndrome / Joseph L Demer -- Amblyopia / Robert F Hess and Nigel Daw -- Strabismus / Christopher S von Bartheld, Scott A Croes, and L Alan Johnson -- Albinism / Gerald F Cox and Anne B Fulton -- Aniridia / Elias I Traboulsi -- Color vision defects / Maureen Neitz and Jay Neitz -- Acute retinal vascular occlusive disorders / Sohan Singh Hayreh -- Retinal photic injury: laboratory and clinical findings / Daniel Organisciak and Marco Zarbin -- Vascular damage in diabetic retinopathy / Timothy S Kern and Suber Huang -- Neovascularization in diabetic retinopathy / Corey B Westerfeld and Joan W Miller -- Diabetic macular edema / Pascale Massin, Michel Paques, and Jean-Antoine Pournaras --Dry age-related macular degeneration and age-related macular degeneration pathogenesis / Marco Zarbin and Janet S Sunness -- Neovascular age-related macular degeneration / David E Lederer, Scott W Cousins, and Karl G Csaky -- Inhibition of / Anthony P Adamis and Adrienne Berman -- Retinal detachment / Steven K Fisher and Geoffrey P Lewis -- Retinopathy of prematurity / Mary Elizabeth Hartnett and Cynthia A Toth -- Retinal energy metabolism / Robert A Linsenmeier -- Retinitis pigmentosa and related disorders / Eric A Pierce -- Visual prostheses and other assistive devices / Muhammad Ali Memon and Joseph F Rizzo III -- Paraneoplastic retinal degeneration / Grazyna Adamus -- Cellular repopulation of the retina / Budd AL Tucker, Michael J Young, and Henry J Klassen -- Proliferative vitreoretinopathy / Clyde Guidry -- Immunologic mechanisms of uveitis / Steven Yeh, Zhuqing Li, and Robert B Nussenblatt -- Herpesvirus retinitis / Sally S Atherton and Mei Zheng -- Sympathetic ophthalmia / Mirunalini Kumaradas and Narsing A Rao -- Scleritis / Srilakshmi M Sharma and James T Rosenbaum -- Infectious uveitis / Pooja Bhat, Allen Tony Jackson, and C Stephen Foster -- Ocular sarcoidosis / Russell N Van Gelder and Suzanne M Dintzis
- Access
- Registration required for PDF access.
- Format
- e-Book
- Location
- Online
Neuroplasticity : New Biochemical Mechanisms
https://libcat.nshealth.ca/en/permalink/provcat30500
Costa e Silva, JA.
--London, England:
Springer Healthcare
, c2011.
- Available Online
- View e-Book
- Location
- Online
- Available Online
- View e-Book
- Author
- Costa e Silva, JA
- Other Authors
- Macher, JP
- Olié, JP
- Place of Publication
- London, England
- Publisher
- Springer Healthcare
- Date of Publication
- c2011
- Physical Description
- 1 online resource (70 p.)
- ISBN
- 9781908517180
- Subjects (MeSH)
- Neuronal Plasticity
- Neurobiology
- Subjects (LCSH)
- Neurology
- Format
- e-Book
- Location
- Online
Adler's physiology of the eye
https://libcat.nshealth.ca/en/permalink/provcat31646
Leonard A. Levin, Siv F.E. Nilsson, James Ver Hoeve ... [et al.].
(11th ed.)
--Edingburg:
Saunders Elsevier
, c2011.
- Available Online
- View e-Book
- Access
- Registration required for PDF access.
- Location
- Online
Drs. Paul L. Kaufman, Albert Alm, Leonard A Levin, Siv F.E. Nilsson, James Ver Hoeve, and Samuel Wu present the 11th Edition of the classic text Adler's Physiology of the Eye, updated to enhance your understanding of ocular function. This full-color, user-friendly edition captures the latest molecular, genetic, and biochemical discoveries and offers you unparalleled knowledge and insight into the physiology of the eye and its structures. A new organization by function, rather than anatomy, help…
- Available Online
- View e-Book
- Other Authors
- Levin, Leonard A
- Responsibility
- Leonard A. Levin, Siv F.E. Nilsson, James Ver Hoeve ... [et al.]
- Edition
- 11th ed.
- Alternate Title
- Physiology of the eye
- Place of Publication
- Edingburg
- Publisher
- Saunders Elsevier
- Date of Publication
- c2011
- Physical Description
- 1 online resource (xii, 795 p.)
- ISBN
- 9780323081160
- Subjects (MeSH)
- Ocular Physiological Phenomena
- Subjects (LCSH)
- Eye--Physiology
- Abstract
- Drs. Paul L. Kaufman, Albert Alm, Leonard A Levin, Siv F.E. Nilsson, James Ver Hoeve, and Samuel Wu present the 11th Edition of the classic text Adler's Physiology of the Eye, updated to enhance your understanding of ocular function. This full-color, user-friendly edition captures the latest molecular, genetic, and biochemical discoveries and offers you unparalleled knowledge and insight into the physiology of the eye and its structures. A new organization by function, rather than anatomy, helps you make a stronger connection between physiological principles and clinical practice; and more than 1,000 great new full-color illustrations help clarify complex concepts.
- Contents
- Focusing of an image on the retina -- Physiology of optical media -- Direction of gaze -- Nutrition of the eye -- Protection of the eye -- Photoreception -- Visual processing in the retina -- Non-perceptive vision -- Visual processing in the brain -- Visual perception -- Development and deprivation of vision.
- Access
- Registration required for PDF access.
- Format
- e-Book
- Location
- Online
JIMD Reports : case and research reports, 2011/1
https://libcat.nshealth.ca/en/permalink/provcat28827
SSIEM.
--Berlin:
Springer ; SSIEM
, c2011.
- Available Online
- View e-Book
- Location
- Online
JIMD Reports publishes case and short research reports in the area of inherited metabolic disorders. Case reports highlight some unusual or previously unrecorded feature relevant to the disorder, or serve as an important reminder of clinical or biochemical features of a Mendelian disorder.
- Available Online
- View e-Book
- Other Authors
- Society for the Study of Inborn Errors of Metabolism
- Responsibility
- SSIEM
- Alternate Title
- Journal of inherited metabolic disorders reports
- Place of Publication
- Berlin
- Publisher
- Springer ; SSIEM
- Date of Publication
- c2011
- Physical Description
- 1 online resource (vi, 136 p.)
- Series Vol.
- v. 1
- Series Title
- JIMD reports
- ISBN
- 9783642177088 (e-ISBN)
- 9783642177071
- ISSN
- 2192-8312 (electronic)
- Subjects (MeSH)
- Metabolism, Inborn Errors
- Subjects (LCSH)
- Metabolic diseases
- Abstract
- JIMD Reports publishes case and short research reports in the area of inherited metabolic disorders. Case reports highlight some unusual or previously unrecorded feature relevant to the disorder, or serve as an important reminder of clinical or biochemical features of a Mendelian disorder.
- Format
- e-Book
- Location
- Online
Topics in Dental Biochemistry
https://libcat.nshealth.ca/en/permalink/provcat29250
by Martin Levine.
--Berlin, Heidelberg:
Springer-Verlag
, c2011.
- Available Online
- View e-Book
- Location
- Online
- Available Online
- View e-Book
- Author
- Levine, Martin
- Responsibility
- by Martin Levine
- Place of Publication
- Berlin, Heidelberg
- Publisher
- Springer-Verlag
- Date of Publication
- c2011
- ISBN
- 9783540881162
- Subjects (MeSH)
- Dentistry
- Mouth Diseases - physiopathology
- Biochemical Phenomena
- Subjects (LCSH)
- Dentistry
- Biochemistry
- Format
- e-Book
- Location
- Online
Urolithiasis : Basic Science and Clinical Practice
https://libcat.nshealth.ca/en/permalink/provcat30902
Jamsheer J. Talati ... [et al.], editors.
--London:
Springer
, c2012.
- Available Online
- View e-Book
- Location
- Online
Urolithiasis: Basic Science and Clinical Practice is a comprehensive text that assists urologists in defining the best choice of treatment for each case through a balanced presentation of underlying science, diagnostic methods and practical tips, with additional discussions on educational issues, costs and management of resources. This user-friendly practical resource is replete with full-color illustrations and radiographs, covering all aspects of stone disease, and offering perspectives from…
- Available Online
- View e-Book
- Other Authors
- Talati, Jamsheer J
- Responsibility
- Jamsheer J. Talati ... [et al.], editors
- Place of Publication
- London
- Publisher
- Springer
- Date of Publication
- c2012
- Physical Description
- 1 online resource (xl, 982 p. : 365 ill., 242 ill. in color)
- ISBN
- 9781447143871
- Subjects (MeSH)
- Urolithiasis
- Urinary Calculi - therapy
- Subjects (LCSH)
- Urology
- Abstract
- Urolithiasis: Basic Science and Clinical Practice is a comprehensive text that assists urologists in defining the best choice of treatment for each case through a balanced presentation of underlying science, diagnostic methods and practical tips, with additional discussions on educational issues, costs and management of resources. This user-friendly practical resource is replete with full-color illustrations and radiographs, covering all aspects of stone disease, and offering perspectives from Europe, the Americas, China, South Asia, Africa, and Australia. Topics include the biochemical and physiological basis of stone formation, treatment options, complications, assessment of techniques and technologies available, and guidelines on the prevention of stone recurrence. Urolithiasis: Basic Science and Clinical Practice is the definitive text on stone disease and is a must read for young consultants starting a new practice, and urologists in residence and training.
- Contents
- Part I. Epidemiology -- 1. Epidemiology of Kidney Stones in the European Union -- 2. Epidemiology of Stone Disease in North America -- 3. Epidemiology of Stone Disease in Pakistan -- 4. Epidemiology of Stone Disease in Northern India -- 5. Epidemiology of Stone Disease in Kerala, South India -- 6. Epidemiology of Stone Disease in China -- 7. Epidemiology of Stone Disease in South America -- 8. Epidemiology: South Africa and Sub-Saharan Africa -- 9. Epidemiology of Stone Disease in Australia -- 10. Epidemiology of Stone Disease in Saudi Arabia with an Overview of the Regional Differences -- 11. Epidemiology of Stone Disease in Iran -- 12. Epidemiology of Stone Disease Over a 40-Year Period in Japan -- 13. Epidemiology of Stone Disease in the Russian Federation and Post-Soviet Era -- 14. Renal Stone Disease in Different Racial Groups -- Part II. Etiology -- 15. Stone Composition and Morphology: A Window on Etiology -- 16. The Genetics of Kidney Stones -- 17. Familial Clustering of Stone Disease -- 18. Uric Acid Nephrolithiasis: Basic and Clinical Aspects -- 19. Oxalate and Urolithiasis -- 20. Anti-Inflammatory Proteins in Kidney Stone Matrix -- 21. Physiology of Renal Handling of Citrate -- 22. Urinary Citrate and Stone Disease -- 23. Renal Tubular Acidosis and Stone Formation -- 24. Nephrolithiasis and its Interrelationship with Vitamin D, Parathyroid Hormone, and Calcium -- 25. Current Understanding of the Role of Randall's Plaque -- 26. Melamine-Associated Urinary Stone -- 27. Trace Elements in Urolithiasis -- 28. Infection Stones -- 29. Epidemiological and Etiological Considerations -- Part III. Diagnosis -- 30. Diagnosis of Urinary Tract Stones: An Overview -- 31. Diagnosis and Differential Diagnosis of Urinary Tract Stone Disease in Emergency Settings -- 32. The Utilization of Ultrasound in the Diagnosis of Urolithiasis -- 33. The Role of Radiological Imaging -- 34. Radiation Exposure in Uroradiology -- 35. The Use of Low Dose CT Scanning -- 36. The Physics of Ultrasound and X-rays: A Primer for Urologists -- Part IV. Technology and Innovation -- 37. The Stone Surgeon/Lithotomists' Armamentarium: Today and Tomorrow -- 38. Physics and Technique of Shock Wave Lithotripsy (SWL) -- 39. Laser Lithotripsy Physics -- 40. Bioeffects of Shock Wave Lithotripsy -- 41. History and Development of the Ureteroscope: What Does the Future Hold? -- 42. The Operating Room Technicians' and Nurses' Roles in Urologic Surgery -- 43. Innovation in Stone Disease -- Part V. Management Strategies -- 44. The Management of a Patient with an Acute Stone Problem -- 45. Open Surgery: Current Status and Techniques -- 46. Shock Wave Lithotripsy: Present Indications and Future Prospects -- 47. What You Should Know about Extracorporeal Shock Wave Lithotripsy and How You Can Improve Your Performance -- 48. Examples of Clinical Problems that Might Be Encountered in Patients Treated with Extracorporeal Shockwave Lithotripsy -- 49. SWL of Renal and Ureteral Stones: The Chinese Experience -- 50. Retrograde Intrarenal Surgery (RIRS) -- 51. Percutaneous Nephrolithotomy (PCNL) -- 52. Tubeless Percutaneous Nephrolithotomy -- 53. Minimally Invasive Percutaneous Nephrolithotomy: The Chinese Approach -- 54. Percutaneous Nephrostomy, Antegrade Stent Placement, and Radiological Control of Post- PCNL Bleeding -- 55. Management Strategies for Staghorn Stones -- 56. Ureteral Stone Management: An Overview -- 57. Ureteroscopy for Ureteric Stones -- 58. Tricks for Successful Ureteroscopy -- 59. Lasers in Stone Disease -- 60. Ureteric Stents: Their Use and Abuse -- 61. Ureteric Stenting: Tips and Tricks -- 62. Transperitoneal Laparoscopic and Retroperitoneoscopic Stone Treatment -- 63. Role of Robotic-Assisted Surgery in the Management of Urolithiasis -- 64. Management of Urinary Bladder Calculi -- 65. Current Status of Medical Expulsion Therapy for Urinary Calculi -- 66. Dissolution of Stones by Oral and Irrigative Therapy -- 67. Traditional Chinese Medicine for Treatment of Urinary Stones -- 68. Patient Safety and the Importance of Informed Consent -- 69. Anesthesia and Pain Relief for Procedures Performed to Manage Urolithiasis -- Part VI. Management of Stones under Special Circumstances -- 70. Shock Wave Lithotripsy, Endourological Intervention, and Hemostatic Defects -- 71. Cardiac Rhythm Management Devices -- 72. Stone Disease in Pregnancy -- 73. Minimally Invasive Treatment of Calculi in Renal Anomalies -- 74. Kidney Stones and Chronic Kidney Disease -- 75. Calculus Renal Failure in Pakistan -- 76. Urolithiasis in Renal Transplant Donors and Recipients -- 77. Primary Hyperoxaluria: The Role and Timing of Liver and Kidney Transplantation -- Part VII. Pediatric Urolithiasis -- 78. Metabolic Stone Disease in Children -- 79. Pediatric Urinary Stone Disease in China -- 80. Patient Evaluation and Comparison of Stone-Removing Strategies in Pediatric Patients with Urinary Tract Stones -- 81. Pediatric Vesicle Stone -- 82. Shock Wave Lithotripsy for Renal Stone in Children -- 83. Endourological Approaches to Renal and Ureteric Calculi in Children -- Part VIII. Prevention of Recurrence -- 84. Biochemical Risk Evaluation in Patients with Urolithiasis -- 85. Application of Physical Methods to Kidney Stones and Randall's Plaque Characterization -- 86. General and Specific Dietary Advice for the Prevention of Stone Recurrence -- 87. Overview of Stone Prevention Strategies in China -- 88. Management of Hypercalciuria and Oxalates in the Prevention of Stone Recurrence -- 89. Citrate Therapy for Calcium and Uric Acid Stones -- 90. The Importance of Water and Other Fluids in the Prevention of Stone Recurrence -- 91. Orthophospates -- 92. Management of Cystinuria -- 93. The Detection and Management of Primary Hyperparathyroidism in Patients with Urolithiasis -- 94. Normocalcemic Hyperparathyroidism: An Illustrative Case Scenario -- 95. How to Perform a Successful Exploration of the Neck for Primary Hyperparathyroidism -- Part IX. Education, Training, Assessment, and Development -- 96. Professional Development and Competence of Physicians -- 97. Assessment in Post-Graduate Training -- 98. Assessment of Competence -- 99. Modern Concepts on Cognito-Psychomotor Skill Development -- 100. Integration of Competences -- 101. Education and Training of an Academic Urologic Surgeon -- 102. Advanced Training of a Practicing Urologist in Stone Disease Management -- 103. Across Semantic Turfs: The Need for Broader Education -- 104. Stimulating Research and Innovation in Residents -- Part X. Equitable Management of Stone Disease -- 105. Bringing Sophisticated High Technological Surgical Care to the Rural Masses: What Is India Doing? -- 106. Bringing Highly Technological Urolithiasis Care to a Billion People: What Is China Doing? -- 107. Lithotriptor Sharing -- 108. Choosing and Purchasing Expensive Medical Equipment: A Hospital Perspective -- 109. Comparative Costs of Various Treatment Strategies and Preventive Measures -- 110. Financial Options for Purchase, Lease, and Hire of Lithotriptors -- 111. The Engagement of Philanthropy -- 112. The Impact on Health Care of the Recent Global Epidemiological Trends in Urolithiasis -- 113. Societal Changes and the Etiology of Stone Disease -- Part XI. Case Scenarios -- 114. Case Scenarios and Interesting Images in Urolithiasis -- Part XII. Epilogue.
- Format
- e-Book
- Location
- Online
Diabetes & C-Peptide : Scientific and Clinical Aspects
https://libcat.nshealth.ca/en/permalink/provcat31009
Anders A.F. Sima, editor.
--New York, NY:
Humana Press
, c2012.
- Available Online
- View e-Book
- Location
- Online
In Diabetes & C-Peptide: Scientific and Clinical Aspects, a renowned group of leading researchers and physicians offers a comprehensive overview of the role of C-Peptide in type 1 diabetes. The book is organized in five sections. An Introductory section provides the background and key features of C-peptide's physiological function and how its deficiency contributes to complications. The second section describes up-to-date information on the biochemical and molecular actions of C-peptide, includ…
- Available Online
- View e-Book
- Other Authors
- Sima, Anders A.F
- Responsibility
- Anders A.F. Sima, editor
- Place of Publication
- New York, NY
- Publisher
- Humana Press
- Date of Publication
- c2012
- Physical Description
- 1 online resource (xiii, 169 p. : 63 ill., 35 ill. in color)
- Series Title
- Contemporary diabetes
- ISBN
- 9781617793912
- Subjects (MeSH)
- C-Peptide - physiology
- C-Peptide - therapeutic use
- Diabetes Complications - prevention & control
- Diabetes Mellitus, Type 1 - drug therapy
- Subjects (LCSH)
- Diabetes
- Endocrinology
- Biochemistry
- Abstract
- In Diabetes & C-Peptide: Scientific and Clinical Aspects, a renowned group of leading researchers and physicians offers a comprehensive overview of the role of C-Peptide in type 1 diabetes. The book is organized in five sections. An Introductory section provides the background and key features of C-peptide's physiological function and how its deficiency contributes to complications. The second section describes up-to-date information on the biochemical and molecular actions of C-peptide, including membrane binding, interactions with insulin as well as the interaction between C-peptide and zinc and effects on microvascular vasoreactivity. The third section summarizes in vivo animal studies of the type 1 diabetic complications. The fourth section reviews the clinical efforts of C-peptide on inflammation, cardiovascular complication, neuropathy and nephropathy. Finally, in the Conclusions section, a summary of the present state of C-peptide, outstanding questions, and the likely direction of the field are offered. Developed by the foremost investigators in the rapidly moving field of C-peptide research, Diabetes & C-Peptide: Scientific and Clinical Aspects is an important contribution to the literature for all researchers and physicians concerned about type 1 diabetes.
- Contents
- C-peptide and Insulin: A Happy Marriage -- Peptide Interactions of Proinsulin C-peptide -- The Effect of Combined C-peptide and Zinc on Cellular Function -- C-Peptide Signaling in the Kidney and Protection from Diabetic Nephropathy -- Role of C-Peptide in the Regulation of Microvascular Blood Flow -- Is NO-eNOS a target for C-peptide action and its protective effects on diabetic nephropathy? -- Renoprotective Effects of C-Peptide in Type I Diabetes -- The Mechanisms Underlying the Effects of C-peptide on Type I Diabetic Neuropathy -- C-peptide and Type 1 Diabetic Encephalopathy -- C-peptide: a New Molecule with Anti-Inflammatory Properties -- C-peptide: Connecting Diabetes with Macrovascular Complications -- C-peptide and Diabetic Neuropathy in Patients with Type I Diabetes -- Proatherogenic Effects of C-Peptide -- Conclusions and Future Outlook.
- Format
- e-Book
- Location
- Online
Radionuclide and Hybrid Bone Imaging
https://libcat.nshealth.ca/en/permalink/provcat31084
Ignac Fogelman, Gopinath Gnanasegaran, Hans Wall, editors.
--Berlin, Heidelberg:
Springer
, c2012.
- Available Online
- View e-Book
- Location
- Online
The accurate identification of pathology in the skeleton is an extremely important goal, and the great strength of the radionuclide bone scan is its ability to identify functional change before structural change occurs. Over the years, the indications for bone scan have evolved to include benign disorders as well as malignancies. Further striking developments include the emergence of PET and of new tracers that offer enhanced capabilities, such as 18F-fluoride. The most dramatic advance, howeve…
- Available Online
- View e-Book
- Other Authors
- Fogelman, Ignac
- Gnanasegaran, Gopinath
- Wall, Hans
- Responsibility
- Ignac Fogelman, Gopinath Gnanasegaran, Hans Wall, editors
- Place of Publication
- Berlin, Heidelberg
- Publisher
- Springer
- Date of Publication
- c2012
- Physical Description
- 1 online resource (xiv, 1046 p. : 641 ill., 294 ill. in color)
- ISBN
- 9783642024009
- Subjects (MeSH)
- Bone Diseases - diagnostic imaging
- Bone and Bones - diagnostic imaging
- Positron-Emission Tomography - methods
- Positron-Emission Tomography Computed Tomography - methods
- Subjects (LCSH)
- Nuclear medicine
- Oncology
- Orthopedics
- Abstract
- The accurate identification of pathology in the skeleton is an extremely important goal, and the great strength of the radionuclide bone scan is its ability to identify functional change before structural change occurs. Over the years, the indications for bone scan have evolved to include benign disorders as well as malignancies. Further striking developments include the emergence of PET and of new tracers that offer enhanced capabilities, such as 18F-fluoride. The most dramatic advance, however, has been the development of hybrid imaging systems that combine the strengths of different modalities. This book, written by authors with national and international reputations in the field, covers all aspects of radionuclide and hybrid bone imaging. Introductory sections present the basic science and consider the current status and limitations of conventional radiological techniques. The underlying principles of PET-CT and SPECT-CT are carefully explained, and the value of different PET and SPECT tracers, assessed. The role of single- and dual-modality approaches in the imaging of benign bone diseases and malignancies is then discussed in detail in a series of well-illustrated chapters. The pathologies addressed include metabolic bone disease, arthritis, bone and joint infections, primary bone and soft tissue tumors, and metastases from breast and prostate cancer. A further section considers the role of bone scintigraphy in the pediatric patient, and the closing chapters focus on miscellaneous subjects, including bone densitometry and radionuclide targeted therapy.
- Contents
- BONE AND BASICS SCIENCES -- Anatomy of the Skeletal System -- Physiology of Bone Formation, Remodeling, and Metabolism -- Pathophysiology of Bone Metastases -- Skeletal Tracer Kinetics: Science and Practice -- Biochemical Markers in Bone Diseases -- BONE AND CONVENTIONAL RADIOLOGY -- Basics of CT -- Basic Principles of MRI -- Radiological Imaging in Metastatic Bone Disease and Myeloma: Current Status and Limitations -- Radiological Imaging of Primary Benign and Malignant Bone Tumours -- Radiological Imaging in Trauma and Sports Injuries: Current Status and Limitations -- Radiological Imaging in Arthritis: Current Status and Limitations -- RADIONUCLIDE BONE IMAGING: SCIENCE AND PRACTICE -- Basic Principles of SPECT and PET Imaging -- Technical Challenges and Pitfalls in Hybrid Imaging -- Bone Scintigraphy: SPECT and PET Tracers -- Bone Scintigraphy: Patterns, Variants, Limitations and Artefacts -- Soft Tissue Uptake in Radionuclide Bone Scintigraphy -- BONE SCINTIGRAPHY IN BENIGN BONE DISEASE -- Bone Scintigraphy in Metabolic Bone Disease -- Bone Scintigraphy in Arthritis -- Bone Scintigraphy in Trauma and Sport Injuries -- SPECT and PET in the Assessment of Bone Infections -- BONE SCINTIGRAPHY IN BENIGN BONE DISEASE -- Nuclear Medicine in the Assessment of Painful Joint Prostheses -- Radionuclide Bone Imaging in Skeletal Tuberculosis -- Hybrid Imaging in the Management of Complex Foot and Ankle Problems -- Wrist Registration: Conventional Radionuclide and SPECT/CT Imaging -- BONE SCINTIGRAPHY IN BONE METASTASES -- Prostate Cancer: Role of Conventional Radionuclide and Hybrid Bone Imaging -- Breast Cancer: Role of Planar, SPECT and PET in Imaging Bone Metastases -- Lung, Thyroid, Renal Cancer, Myeloma and Neuroendocrine Cancers: Role of Planar, SPECT and PET in Imaging Bone Metastases -- Conventional Nuclear Medicine and Hybrid Imaging in Monitoring the Treatment of Skeletal Malignancy -- Potential Applications and Limitations of SPECT-CT in Classifying Bone Lesions in Patients with Cancer -- Primary Bone and Soft Tissue Tumours: Role of SPECT -- Primary Bone and Soft Tissue Tumours: Role of 18FDG PET -- Radioisotopes in the Treatment of Bone Metastases -- Radionuclide Bone Marrow Imaging in Cancer Patients -- PAEDIATRIC BONE SCINTIGRAPHY -- Pediatric Bone Scintigraphy: Variants and Limitations -- Paediatric Bone Scintigraphy: Benign Bone Disease -- Paediatric Bone Scintigraphy: Bone Metastases -- Hybrid Bone Imaging in Pediatrics -- BONE AND MISCELLANEOUS SCENARIOS -- Bone Densitometry: Science and Practice -- Radiosynovectomy: Science and Practice -- Radiosynoviorthesis (Radiation Synovectomy) of Knee Joint -- Common Orthopaedic Presentations -- Radiological Imaging in Infection: Current Status and Limitations.
- Format
- e-Book
- Location
- Online
