Congenital Hyperinsulinism : A Practical Guide to Diagnosis and Management
https://libcat.nshealth.ca/en/permalink/provcat44051
Diva D. De León-Crutchlow, Charles A. Stanley, editors.
--Cham:
Humana Press
, 2019.
- Available Online
- View e-Book
- Location
- Online
This unique book is a practical guide for the clinician faced with the challenge of diagnosing and managing neonates, infants and children with congenital hyperinsulinism (HI), within the framework of pathophysiology and molecular genetics. Major advances have been made in HI research over the past two decades, and with this better understanding of the molecular genetics of HI, a “personalized” approach to management according to the type of hyperinsulinism, and particularly according to the li…
- Available Online
- View e-Book
- Other Authors
- De León-Crutchlow, Diva D.
- Stanley, Charles A.
- Responsibility
- Diva D. De León-Crutchlow, Charles A. Stanley, editors
- Place of Publication
- Cham
- Publisher
- Humana Press
- Date of Publication
- 2019
- Physical Description
- 1 online resource (xv, 165 p.) : 22 illus., 12 illus. in color
- Series
- Contemporary Endocrinology
- Series Title
- Contemporary endocrinology
- ISBN
- 9783030029616
- 9783030029609 (Print ed.)
- 9783030029623 (Print ed.)
- ISSN
- 2523-3785
- Specialty
- Diabetes Mellitus
- Abstract
- This unique book is a practical guide for the clinician faced with the challenge of diagnosing and managing neonates, infants and children with congenital hyperinsulinism (HI), within the framework of pathophysiology and molecular genetics. Major advances have been made in HI research over the past two decades, and with this better understanding of the molecular genetics of HI, a “personalized” approach to management according to the type of hyperinsulinism, and particularly according to the likelihood of focal hyperinsulinism, is starting to emerge. The opening chapter discusses HI diagnosis using biochemical approaches and phenotype characterization. The various forms of HI are then presented in detail in three main categories: diazoxide-responsive, diazoxide-unresponsive and syndromic HI. Both medical and surgical management strategies are then discussed, covering imaging, histology, surgical approach, and post-operative management. Complications, such as feeding problems, and long-term outcomes, such as neurodevelopmental issues, are carefully considered in the final chapter. Practical and user-friendly, Congenital Hyperinsulinism is the go-to resource for pediatric endocrinologists, residents and fellows, general pediatricians and neonatologists.
- Contents
- Approach to the Diagnosis of Neonates and Infants with Persistent Hypoglycemia -- Diazoxide-Responsive Forms of Congenital Hyperinsulinism -- Diazoxide-Unresponsive Forms of Congenital Hyperinsulinism -- Syndromic Causes of Congenital Hyperinsulinism -- Molecular Diagnosis of Congenital Hyperinsulinism -- Medical Management of Hyperinsulinism -- 18F-DOPA PET -- Histopathology of the Pancreas in Congenital Hyperinsulinism -- Surgery for Congenital Hyperinsulinism -- Perioperative Management of Hyperinsulinism -- Management of the Child with Persistent Hypoglycemia After Surgery -- Management of Diabetes and Pancreatic Insufficiency after Pancreatectomy -- Feeding Problems in Congenital Hyperinsulinism -- Neurodevelopmental Outcomes.
- Format
- e-Book
- Location
- Online
Cadmium Toxicity : New Aspects in Human Disease, Rice Contamination, and Cytotoxicity
https://libcat.nshealth.ca/en/permalink/provcat44135
Seiichiro Himeno, Keiko Aoshima, editors.
--Singapore:
Springer
, 2019.
- Available Online
- View e-Book
- Location
- Online
This volume focuses on cadmium (Cd) exposure, its effects on human health, the mechanism of Cd accumulation and the development of mitigation technologies. Further, it discusses clinical, epidemiological, agricultural, toxicological, and biochemical aspects of Cd pollution and presents recent biochemical studies on molecular mechanisms of Cd cytotoxicity and cellular transport as well as the mechanism of Cd-induced disturbances in phosphorus (P) metabolism. It also provides insights into the pa…
- Available Online
- View e-Book
- Other Authors
- Himeno, Seiichiro
- Aoshima, Keiko
- Responsibility
- Seiichiro Himeno, Keiko Aoshima, editors
- Place of Publication
- Singapore
- Publisher
- Springer
- Date of Publication
- 2019
- Physical Description
- 1 online resource (viii, 190 p.) : 68 illus., 51 illus. in color
- Series
- Current Topics in Environmental Health and Preventive Medicine
- ISBN
- 9789811336300
- 9789811336294 (Print ed.)
- 9789811336317 (Print ed.)
- ISSN
- 2364-8333
- Subjects (MeSH)
- Cadmium - toxicity
- Cadmium Poisoning
- Environmental Exposure
- Food Contamination - prevention & control
- Specialty
- Toxicology
- Abstract
- This volume focuses on cadmium (Cd) exposure, its effects on human health, the mechanism of Cd accumulation and the development of mitigation technologies. Further, it discusses clinical, epidemiological, agricultural, toxicological, and biochemical aspects of Cd pollution and presents recent biochemical studies on molecular mechanisms of Cd cytotoxicity and cellular transport as well as the mechanism of Cd-induced disturbances in phosphorus (P) metabolism. It also provides insights into the pathophysiology of itai-itai disease, a serious condition caused by Cd pollution. Cadmium: New Aspects in Human Disease, Rice Contamination, and Cytotoxicity is a valuable resource for scientists involved in heavy metal toxicology, botanical sciences, and regulatory sciences. Addressing the features of Cd pollution in the past and in the present, as well as future perspectives, this is a must-have book for students, researchers and practitioners interested in global and local metal pollution.
- Contents
- Part I. Overview -- 1. Historical Lessons on Cadmium Environmental Pollution Problems in Japan and Current Cadmium Exposure Situation -- Part II. Health Effects of Cadmium in Human Populations and its Relation to Cadmium Exposure Levels -- 2. Recent Clinical and Epidemiological Studies of Itai-Itai Disease (Cadmium-Induced Renal Tubular Osteomalacia) and Cadmium Nephropathy in the Jinzu River Basin in Toyama Prefecture, Japan -- 3. Novel Pathological Study of Cadmium Nephropathy of Itai-itai Disease -- 4. Long-Term Follow-Up Study of Residents Exposed to Cadmium in Kakehashi River Basin, Ishikawa, Japan -- 5. Effects of Cadmium Exposure on Life Prognosis -- 6. Cadmium Exposure and Its Effects on the Health Status of Rice Farmers in Akita Prefecture 7. Dietary Cadmium Intake Among General Populations in Japan and East Asia -- Part III. Rice Contamination by Cadmium and its Remediation -- 8. Regulations for Cadmium in Rice and Soil in Japan and Countermeasures to Reduce the Concentrations -- 9. Molecular Mechanism of Cadmium Accumulation in Rice - 10. Mitigation Strategies for Cadmium and Arsenic in Rice -- 11. Development of Low-Cadmium-Accumulating Rice -- Part IV. New Aspects in the Mechanisms of Cadmium Toxicity -- 12. Novel Mechanisms of Cadmium-Induced Toxicity in Renal Cells - 13. Roles of Metal Transporters in Cellular Cadmium Transport in Mammals -- 14. Disturbance in Phosphorus Metabolism by Cadmium Exposure.
- Format
- e-Book
- Location
- Online
Comprehensive Biochemistry for Dentistry : Textbook for Dental Students
https://libcat.nshealth.ca/en/permalink/provcat44220
Anil Gupta.
--Singapore:
Springer
, 2019.
- Available Online
- View e-Book
- Location
- Online
This book combines fundamental concepts of biochemistry and the dental sciences to provide an authentic, coherent and comprehensive text for dental students. It describes in simple language the intricate pathophysiology of biomolecules in health and in diseases of dental and oral tissues. This book also describes the evolution of biochemistry in a chronological order, provides information about the fundamental chemical structure, classification and biological significance of biomolecules, vitam…
- Available Online
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- Author
- Gupta, Anil
- Responsibility
- Anil Gupta
- Place of Publication
- Singapore
- Publisher
- Springer
- Date of Publication
- 2019
- Physical Description
- 1 online resource (xxxv, 604 p.) : 266 illus., 195 illus. in color
- ISBN
- 9789811310355
- 9789811310348 (Print ed.)
- 9789811310362 (Print ed.)
- Subjects (MeSH)
- Biochemical Phenomena
- Dentistry - education
- Specialty
- Biochemistry
- Dentistry
- Abstract
- This book combines fundamental concepts of biochemistry and the dental sciences to provide an authentic, coherent and comprehensive text for dental students. It describes in simple language the intricate pathophysiology of biomolecules in health and in diseases of dental and oral tissues. This book also describes the evolution of biochemistry in a chronological order, provides information about the fundamental chemical structure, classification and biological significance of biomolecules, vitamins and hormones, enriched with flow charts and diagrams for easy understanding and quick reference. It includes chapters on nucleic acids, nutrition and serum enzymes and organ function tests, and offers an innovative approach to familiarize dental students with the biochemical composition of enamel, dentine, cementum and saliva, explaining the biochemical basis of dental caries, periodontal diseases, role of fluorides in caries prophylaxis, fluoride toxicity, and the role of amino acids as anti-hypersensitive agents.
- Contents
- Introduction to Biochemistry -- Part I. Cellular Biochemistry -- Cell and Organelles -- Part II. Structural Biochemistry -- Proteins and Amino acids -- Plasma Proteins -- Haemoglobin -- Carbohydrates -- Lipids -- Nucleic Acids -- Enzymes -- Hormones -- Vitamins -- Part III. Metabolism -- Digestion and Absorption of Proteins -- Metabolism of Proteins and Amino acids -- Digestion and Absorption of Carbohydrates -- Metabolism of Carbohydrates -- Digestion and Absorption of Lipids -- Metabolism of Lipids -- Metabolism of Minerals -- Biological Oxidation -- Part IV. Medical Biochemistry -- Acid-Base Balance -- Nutrition -- Serum Enzymes and Organ Function Tests -- Part: V Immunochemistry -- Immunoglobulins -- Part V. Dental Biochemistry -- Dental Biochemistry.
- Format
- e-Book
- Location
- Online
Thyroid FNA Cytology : Differential Diagnoses and Pitfalls
https://libcat.nshealth.ca/en/permalink/provcat44317
Kennichi Kakudo, editor.
(Second edition)
--Singapore:
Springer
, 2019.
- Available Online
- View e-Book
- Location
- Online
This book offers a comprehensive guide to thyroid fine needle aspiration (FNA) cytology. Borderline/precursor tumors, which were introduced in the 4th edition of the WHO classification of thyroid tumors, are also incorporated. In this second edition, prominent international experts discuss the different approaches to thyroid FNA cytology employed in various countries such as Australia, Canada, China, Korea, Portugal, Switzerland, Taiwan, Thailand, Turkey, Ukraine, the USA, UK, Italy and Japan. …
- Available Online
- View e-Book
- Other Authors
- Kakudo, Kennichi
- Responsibility
- Kennichi Kakudo, editor
- Edition
- Second edition
- Place of Publication
- Singapore
- Publisher
- Springer
- Date of Publication
- 2019
- Physical Description
- 1 online resource (xvii, 577 p.) : 517 illus., 504 illus. in color
- ISBN
- 9789811318979
- 9789811318962 (Print ed.)
- 9789811318986 (Print ed.)
- Subjects (MeSH)
- Biopsy, Fine-Needle
- Diagnosis, Differential
- Thyroid Diseases - diagnosis
- Abstract
- This book offers a comprehensive guide to thyroid fine needle aspiration (FNA) cytology. Borderline/precursor tumors, which were introduced in the 4th edition of the WHO classification of thyroid tumors, are also incorporated. In this second edition, prominent international experts discuss the different approaches to thyroid FNA cytology employed in various countries such as Australia, Canada, China, Korea, Portugal, Switzerland, Taiwan, Thailand, Turkey, Ukraine, the USA, UK, Italy and Japan. The book not only covers key principles of thyroid cytopathology but also addresses technical aspects such as procedural complications, liquid-based cytology, immunocytochemistry, staining procedures, and potential pitfalls. Case-based descriptions and clinical findings, radiologic imaging, cytology, and histopathologic diagnosis – all complemented by a wealth of detailed photographs – will help reader understand and overcome many common dilemmas in daily practice. As such, the book represents an indispensable reference work for all cytopathologists, especially those practicing thyroid cytopathology.
- Contents
- Diagnostic Clues for Thyroid Fine Needle Aspiration Cytology -- Factors Impacting Thyroid Fine Needle Aspiration Cytology and Algorithm for Cytological Diagnosis -- False positive in Thyroid FNA: Causes and how to avoid them -- What’s New in Thyroid Tumor Classification of the new WHO Classification of Endocrine Organs -- International comparison study of thyroid reporting systems -- Introiduction of the Italian Reporting System for Thyroid Cytology -- Introduction of the second edition Bethesda System for Reporting Thyroid Cytopathology -- Australian System for Reporting Thyroid Cytology -- Introduction of the British system for thyroid FNA cytology, including emphasis on multidisciplinary team discussion -- How to triage patients with indeterminate nodule by the Japan Thyroid Association clinical guidelines -- How to Follow Fine-needle Aspiration Biopsy-proven Benign Thyroid Nodules -- How to be considerate to patients with thyroid nodule, lesson from pediatric thyroid cancer screening program in Fukushima after nuclear plant accident -- LBC technique for thyroid FNA cytology -- Specimen adequacy in conventional smear and LBC preparation -- Cytological Features of Papillary Carcinoma on LBC Preparation, Compared with Conventional Preparation -- Cyst or Cystic Papillary Carcinoma -- Cyst Fluid Only Samples -- Thyroglossal Duct Cyst and Other Ectopic Thyroid Tissue in the Neck -- Pitfalls in the Diagnosis of Papillary Thyroid Carcinoma -- Pathologic Basis for Thyroid Ultrasound -- Nuclear features of PTC (BRAF-like tumor) and FA/FTC (RAS like tumor) -- Risk Stratification of Cases with Papillary Thyroid Carcinoma Type Nuclear Features into Low-risk, High-risk and Diagnostic of Malignancy in the Japanese System -- AUS/FLUS in the Bethesda system -- NIFTP in Asian practice -- NIFTP in Western practice -- Preoperative cytological diagnosis of NIFTP -- Tall Cell Variant of Papillary Thyroid Carcinoma vs. Conventional Papillary Thyroid Carcinoma -- Cribriform Variant of Papillary Thyroid Carcinoma -- Papillary Carcinoma, Columnar Cell Variant - Diagnostic Pitfalls and Differential Diagnoses -- Hobnail Variant of Papillary Thyroid Carcinoma -- Solid / trabecular variant of papillary thyroid carcinoma -- Oncocytic and non-oncocytic/ aggressive and non-aggressive variants of papillary carcinoma -- Subacute Thyroiditis or Papillary Carcinoma -- Hyalinizing Trabecular Tumor vs. Papillary Thyroid Carcinoma -- Hyalinizng trabecular tumor in HE samples -- Hashimoto’s Thyroiditis or Papillary Carcinoma -- MALT Lymphoma vs. Hashimoto Thyroiditis -- Malignant lymphoma or metastatic epithelial tumors -- Medullary (C cell) Thyroid Carcinoma or Oxyphilic Follicular Neoplasms -- Medullary (C cell) Carcinoma or Metastatic Carcinoma to Thyroid -- Intrathyroid Thymic Carcinoma vs. Poorly Differentiated Carcinoma -- Parathyroid Adenoma and Its Differential Diagnoses -- Risk-classification of follicular pattern lesions in thyroid FNA cytology (part 1: benign follicular pattern lesion vs FN/SFN) -- Risk-classification of Follicular Pattern Lesions in Thyroid FNA Cytology (part 2: Follicular Adenoma and Follicular Carcinoma) -- Challenges encountered in the cytologic diagnosis of follicular neoplasm -- Hurthle cell neoplasms in HE samples -- Hurthle cell neoplasms in Papanicoloau samples -- Poorly Differentiated Carcinoma vs. Well Differentiated Carcinoma -- Poorly differentiated carcinoma and Anaplastic Carcinoma -- Anaplastic thyroid carcinoma in case-based outline -- Metastatic Renal Cell Carcinoma vs. Follicular Neoplasm -- Necrotic Background in Thyroid FNA Cytology: Anaplastic Transformation or Infarction in Papillary Carcinoma -- Infectious Thyroiditis -- Cytological characteristics related to treatment in Graves disease -- Cytological and histological characteristics after percutaneous ethanol injection and radiofrequency ablation in various thyroid nodules. -- Complications of Fine Needle Aspiration Biopsy -- Pitfalls in Immunocytochemical Study Using Fine Needle Aspiration Samples -- Biochemical Tests of Fine-needle Aspirate as An Adjunct to Cytological Diagnosis for Patients with Thyroid Cancer or Primary Hyperparathyroidism -- Experience in molecular testing using FNA cytology in EU countries -- Molecular testing of thyroid nodules using FNA cytology in USA -- Pitfalls of molecular tests in thyroid FNA cytology -- Pitfalls in Molecular-based Diagnosis Using Thyroid Cytology -- THE FNA CLINIC -- Techniques of Thyroid Fine-Needle Aspiration -- Core needle biopsy vs FNA cytology -- Standard and Rapid Stains in Fine-Needle Aspiration Cytology and Rapid On-Site Evaluation -- Quality Control for Cytology Laboratory in USA -- Pediatric thyroid cancer screening program in Fukushima after nuclear plant accident -- Pathology and cytology of thyroid diseases in pediatric population -- Pathology of radiation-induced thyroid cancer (Lesson from Chernobyl thyroid cancer study) -- A strategy to search for new cytologic criteria for differential diagnostics of thyroid cancers based on current (post-Chernobyl) practice in Ukraine.
- Format
- e-Book
- Location
- Online
Diagnostic Test Accuracy Studies in Dementia : A Pragmatic Approach
https://libcat.nshealth.ca/en/permalink/provcat44429
by A.J. Larner.
(Second edition)
--Cham:
Springer
, c2019.
- Available Online
- View e-Book
- Location
- Online
The new and updated edition of this book explains the key steps in planning and executing diagnostic test accuracy studies in dementia, serving as an introduction to the topic with clear explanations of difficulties and pitfalls. It has been fully revised in light of developments over the past 5 years and includes STARD publications which have appeared since the first edition as well as the use of biomarkers of cognitive disorders as increasingly enshrined in diagnostic criteria. The book cover…
- Available Online
- View e-Book
- Author
- Larner, A. J.
- Responsibility
- by A.J. Larner
- Edition
- Second edition
- Place of Publication
- Cham
- Publisher
- Springer
- Date of Publication
- c2019
- Physical Description
- 1 online resource (xvi, 184 p.) : 12 illus., 5 illus. in color
- ISBN
- 9783030175627
- 9783030175610 (Print ed.)
- 9783030175634 (Print ed.)
- 9783030175641 (Print ed.)
- Subjects (MeSH)
- Dementia - diagnosis
- Diagnostic Techniques and Procedures - standards
- Psychological Tests
- Sensitivity and Specificity
- Specialty
- Psychiatry
- Abstract
- The new and updated edition of this book explains the key steps in planning and executing diagnostic test accuracy studies in dementia, serving as an introduction to the topic with clear explanations of difficulties and pitfalls. It has been fully revised in light of developments over the past 5 years and includes STARD publications which have appeared since the first edition as well as the use of biomarkers of cognitive disorders as increasingly enshrined in diagnostic criteria. The book covers the presentation of study results in terms of measures of discrimination, taking examples from studies in dementia looking at various diagnostic methods including cognitive instruments, neuroimaging, and biochemical studies. The book continues to reflect the author’s own experience in diagnostic test accuracy studies, particularly in the sphere of cognitive screening instruments. Diagnostic Test Accuracy Studies in Dementia encourages clinicians to adopt a pragmatic approach to diagnostic test accuracy studies rooted in day-to-day clinical practice.
- Contents
- 1. Introduction -- 2. Methods (1): Participants and Test Methods -- 3. Methods (2): Statistical Methods -- 4. Results (1): Participants and Test Results -- 5. Results (2): Estimates of Diagnostic Accuracy -- 6. Discussion -- 7. Future Prospects for Diagnostic Test Accuracy Studies in Dementia.
- Format
- e-Book
- Location
- Online
The Diabetes Textbook : Clinical Principles, Patient Management and Public Health Issues
https://libcat.nshealth.ca/en/permalink/provcat44446
Joel Rodriguez-Saldana, editor.
--Cham:
Springer
, c2019.
- Available Online
- View e-Book
- Location
- Online
Diabetes has become a worldwide health problem, the global estimated prevalence approaches ten percent and the burden of this disease in terms of morbidity and mortality is unprecedented. The advances acquired through the knowledge of the mechanisms of the disease and the variety of therapeutic approaches contrast with the inability of private and public health systems in underdeveloped and even developed countries to achieve the goals of treatment. This paradox has been described in many sourc…
- Available Online
- View e-Book
- Other Authors
- Rodriguez-Saldana, Joel
- Responsibility
- Joel Rodriguez-Saldana, editor
- Place of Publication
- Cham
- Publisher
- Springer
- Date of Publication
- c2019
- Physical Description
- 1 online resource (xx, 1040 p.) : 212 illus., 183 illus. in color
- ISBN
- 9783030118150
- 9783030118143 (Print ed.)
- 9783030118167 (Print ed.)
- Subjects (MeSH)
- Diabetes Mellitus
- Specialty
- Diabetes Mellitus
- Abstract
- Diabetes has become a worldwide health problem, the global estimated prevalence approaches ten percent and the burden of this disease in terms of morbidity and mortality is unprecedented. The advances acquired through the knowledge of the mechanisms of the disease and the variety of therapeutic approaches contrast with the inability of private and public health systems in underdeveloped and even developed countries to achieve the goals of treatment. This paradox has been described in many sources: the surge of scientific advances contrast with an unprecedented amount of human suffering. Thus, a patient centered and an evidence based approach with the capacity to produce measurable clinical and economic outcomes is required. The purpose of this textbook is multiple: to offer a comprehensive resource covering all aspects of outpatient management; to address diabetes as a health problem from an epidemiological, economic and clinical perspective; to discuss the role of social determinants of health on the worldwide increase in diabetes; to highlight the challenges and obstacles in providing adequate care; and to outline a multidisciplinary approach to management in which medical visits retain their importance as part of a team comprising the patient, his or her family and a multidisciplinary group of health professionals who are able to move beyond the traditional approach of diabetes as a disease and greatly improve outcomes.
- Contents
- Preface: A New Disease? -- Part I. Magnitude of the Problem from an Individual and Social Context -- The Dynamics of Diabetes Prevalence, Morbidity and Mortality -- Economic Costs, from Individuals to Health Systems: Evidence from a Middle Income Country -- The Ecological Approach to Self-Care in Diabetes -- Social Determinants of Health and Diabetes Outcomes -- Part II. Diagnosis, Classifications and Mechanisms of Disease -- Definition, Diagnostic Criteria, Screening, Diagnosis and Classification of Diabetes and Categories of Glucose Intolerance -- Pathophysiology of Type 1 Diabetes -- Pathophysiology of Type 2 Diabetes -- Genetic Determinants of Type 2 Diabetes -- Gene Expression Modifications in Type 2 Diabetes -- The Immune System and Inflammation in Type 2 Diabetes -- Dysfunction and Death of Pancreatic Beta Cells in Type 2 Diabetes -- Obesity in the Pathophysiology of Diabetes -- Pathogenesis of Gestational Diabetes -- Non-Alcoholic Fatty Liver in the Pathogenesis of Diabetes -- Part III. Global Experiences in Diabetes Care -- Diabetes Management in Europe -- Diabetes Management in Asia -- Diabetes Management in the United States -- Diabetes Management in Africa -- Part IV. Basic Components of Management: Patient Centeredness, Evidence-Based Medicine and Outcomes. Challenges for Implementation -- The Patient-Centered Medical Home, Primary Care and Diabetes -- Outpatient Diabetes Management and the Chronic Care Model -- Clinical Practice Guidelines for Diabetes -- Quality of Diabetes Care: Measuring Clinical Impact, Cost Effectiveness and Patient Experience of Care -- Clinical Inertia in Diabetes: The Role of Physicians -- Patient Adherence in Diabetes: Challenges, Myths and Realities -- Part V. Resources of Support for Persons with Diabetes -- Challenges and Opportunities in Diabetes Education -- Diabetes and Mental Health: From Distress to Depression -- Tools of Self-Care: Self-Monitoring of Blood Glucose and Tele-health Resources -- Continuous Glucose Monitoring and Clinical Decision Making -- Diabetes and Lifestyle Medicine -- Evidence and Implementation of Nutrition Therapy in Persons with Diabetes -- Evidence and Implementation of Physical Activity and Exercise -- Part VI. Drug Therapy -- The “Old” Oral Antidiabetics -- Incretin Therapies: Current Use and Emerging Possibilities -- Sodium Glucose Transporter Inhibitors -- Insulin in Outpatient Diabetes Management -- Insulin Pump Therapy -- Part VII. Cardiovascular Risk Factors -- Diabetes and Hypertension -- Diabetes and Atherogenic Dyslipidemia -- Diabetes and Obesity -- Diabetes and Smoking -- Part VIII.Acute Complications -- Hyperglycemic Crisis: Diabetic (ketoacidosis (DKA) -- Hypoglycemia: Diagnosis, Management and Prevention -- Inpatient Management of Diabetes and Hyperglycemia -- Diabetes and Infection -- Part IX. Chronic Complications -- Diabetes and Stroke: The Role of Glucose Regulation -- Diabetes and Peripheral Artery Disease -- Biochemical and Molecular Mechanisms of Vascular Complications in Diabetes -- Ophthalmologic Eye Disease -- Diabetes and Oral Health -- Renal Disease in Diabetes -- Peripheral Diabetic Neuropathies -- Diabetic Cardiac Autonomic Neuropathy -- Autonomic Visceral Neuropathy and Gastrointestinal Disorders -- Urologic Complications and Sexual Dysfunction -- Musculoskeletal Complications of Diabetes -- Diabetes and the Skin -- Foot Complications -- Diabetes and Cancer -- Part X. Diabetes in Special Populations -- Children and Adolescents -- Pregnancy: Pregestational and Gestational Management -- The Elderly with Diabetes -- Part XI. Diabetes Prevention -- Prevention of Type 2 Diabetes: Evidence and Challenges -- Part XII. Novel Therapeutic Approaches: Evidence-Based and Others -- Insulin Pumps and Closed Loop Systems and the Artificial Pancreas -- Unproven Therapies for Diabetes.
- Format
- e-Book
- Location
- Online
Nutritional and Medical Management of Kidney Stones
https://libcat.nshealth.ca/en/permalink/provcat44617
Haewook Han, Walter P. Mutter, Samer Nasser, editors.
--Cham:
Humana Press
, c2019.
- Available Online
- View e-Book
- Location
- Online
This text comprehensively covers the nutritional and medical management and prevention of kidney stones. Sections address types of stones, nutritional risks, medical and pharmaceutical managements, prevention of recurrence, and special consideration of stone risks among specific diseases such as obesity with gastric bypass, chronic kidney disease, and gastric intestinal disorders. Diagnosis of kidney stones, urinalysis and biochemical indices, dietary assessment, and medical nutrition therapy f…
- Available Online
- View e-Book
- Other Authors
- Han, Haewook
- Mutter, Walter P.
- Nasser, Samer
- Responsibility
- Haewook Han, Walter P. Mutter, Samer Nasser, editors
- Place of Publication
- Cham
- Publisher
- Humana Press
- Date of Publication
- c2019
- Physical Description
- 1 online resource (xxxi, 353 p.) : 54 illus., 32 illus. in color
- Series
- Nutrition and Health
- Series Title
- Nutrition and health (Totowa, N.J.)
- ISBN
- 9783030155346
- 9783030155339 (Print ed.)
- 9783030155353 (Print ed.)
- 9783030155360 (Print ed.)
- Subjects (MeSH)
- Kidney Calculi - diet therapy
- Kidney Calculi - prevention & control
- Kidney Calculi - therapy
- Specialty
- Nephrology
- Nutrition Therapy
- Abstract
- This text comprehensively covers the nutritional and medical management and prevention of kidney stones. Sections address types of stones, nutritional risks, medical and pharmaceutical managements, prevention of recurrence, and special consideration of stone risks among specific diseases such as obesity with gastric bypass, chronic kidney disease, and gastric intestinal disorders. Diagnosis of kidney stones, urinalysis and biochemical indices, dietary assessment, and medical nutrition therapy for specific types of kidney stones are also included. In addition, case studies are provided in the appendix. Cutting edge research is also highlighted in regards to pharmaceutical treatments and epidemiological findings in nutrition and kidney stones. Nutrition in Medical Management of Kidney Stones will be a practical resource for health professionals in the fields of nutrition, nephrology, urology, and general medicine, as well as medical students, resident physicians, and allied health clinicians whose research, practice, and education includes nutrition and kidney stones.
- Contents
- Part I. Overview -- Epidemiology of Kidney Stones in the U.S.A -- Part II. Basics of Kidney Stone -- Pathophysiology of Kidney Stone Formation -- Basics of Kidney Stones: Dietary Risk Factors of Kidney Stones -- Genetic and Environmental Risk Factors for Kidney Stones -- Part III. Diagnosis and Treatment -- Evaluation of Patients with Nephrolithiasis -- Kidney Stone Removal Procedures and Emerging Therapies -- Part IV. Prevention, Medical and Nutritional Management for Different Types of Stones -- Calcium Stone: Pathophysiology, Prevention, and Medical Management -- Nutritional Management of Calcium Stones -- Medical Management of uric Acid Stones -- Nutritional Management of Uric Acid Stones -- Struvite Stones -- Cystine Stones -- Medical Management of Unknown Stone Types -- Nutritional Management of Unknown Types of Stones -- Part V. Special Consideration -- Bariatric Surgery and Stone Risk -- Nephrolithiasis in Patients with Gastrointestinal Disorders -- Gastrointestinal Disease and Stone Risk: Nutritional Management -- Nephrolithiasis in Kidney Transplant -- Nutritional Management of Nephrolithiasis in Chronic Kidney Disease -- Kidney Stone: Diety, Myth, and Realty -- Herbal Use in the Nutrition Management of Kidney Stones -- Nephrolithiasis Nutrition Therapy in the Pediatric Populations -- Evaluation and Management of Pediatric Nephrolithiasis -- Part VI. Resources -- Dietary Database of Oxalates -- Kidney Stone Disease: Online and Educational Resources -- Medical Nutrition Therapy and Evidence-Based Practice -- Stone Disease Research -- Appendices.
- Format
- e-Book
- Location
- Online
Adolescent Health and Wellbeing : Current Strategies and Future Trends
https://libcat.nshealth.ca/en/permalink/provcat44756
Alessandro Pingitore, Francesca Mastorci, Cristina Vassalle, editors.
--Cham:
Springer
, c2019.
- Available Online
- View e-Book
- Location
- Online
This book presents a detailed and updated review of the widespread changes that take place during adolescence, adopting a preventive perspective that reflects physical, social, cognitive, and emotional changes. It addresses a broad range of aspects, including: the preventive programs and their systemic effects; the role of environment in influencing the healthy behaviors of adolescents and young adults; the use of e-Health technology in health and behavioral interventions for adolescents; and t…
- Available Online
- View e-Book
- Other Authors
- Pingitore, Alessandro
- Mastorci, Francesca
- Vassalle, Cristina
- Responsibility
- Alessandro Pingitore, Francesca Mastorci, Cristina Vassalle, editors
- Place of Publication
- Cham
- Publisher
- Springer
- Date of Publication
- c2019
- Physical Description
- 1 online resource (xii, 352 p.) : 45 illus., 37 illus. in color
- ISBN
- 9783030258160
- 9783030258153 (Print ed.)
- 9783030258177 (Print ed.)
- 9783030258184 (Print ed.)
- Subjects (MeSH)
- Adolescent
- Health Promotion
- Preventive Medicine
- Social Determinants of Health
- Subjects (LCSH)
- Pediatrics
- Health promotion
- Primary care (Medicine)
- Medical policy
- Child psychiatry
- Specialty
- Adolescent Health
- Abstract
- This book presents a detailed and updated review of the widespread changes that take place during adolescence, adopting a preventive perspective that reflects physical, social, cognitive, and emotional changes. It addresses a broad range of aspects, including: the preventive programs and their systemic effects; the role of environment in influencing the healthy behaviors of adolescents and young adults; the use of e-Health technology in health and behavioral interventions for adolescents; and the clinical and prognostic implications of primordial prevention in healthy adolescents. All of these elements are subsequently reviewed using a multidimensional approach, in order to offer extensive information on the complex changes that characterize adolescents’ physiological, psychological, and neurobiological development. In addition, the book depicts the preventive strategies currently used in various social settings (school, family, sport club, health policies) aimed not only at reducing lifestyle risk behaviors, but also at improving resilience, happiness, social involvement, self-esteem, and sociability. This update is essential in the light of the fact that, to date, prevention has mainly been directed towards adolescents with physical or mental disorders rather than their healthy peers. As such, the book offers a valuable tool for pediatricians, child and adolescents psychiatrists, and for all professionals involved in Health Promotion and Disease Prevention.
- Contents
- Part I. Primordial Prevention: General Aspects - 1. Preventive Primordial Strategies: Times Are Changing -- 2. Fetal Programming of Adult Disease in a Translational Point of View -- 3. Physical Activity, Sedentary Behaviour and Mental Health in Young People: A Review of Reviews -- 4. Habits and Quality of Diet -- 5. Biochemical Markers in Primordial Prevention: Premises and Promises -- Part II. Adolescents’ Mental Health and Well-Being -- 6. Prenatal and Early Postnatal Influences on Neurodevelopment: The Role of Epigenetics -- 7. The Role of Environmental Enrichment on Neurodevelopment: Emotion Regulation in Adolescence as a Model Paradigm -- 8. Relationship Between Emotions, Sleep and Well-Being -- 9. Adolescents in the 21st Century: Back to Dialogue from Marked Lives vs Dreamed Lives -- Part III. Adolescence and the Social Determinants of Health -- 10. Adolescence and Social Determinants of Health: Family and Community -- 11. The Role of Well-Being in the School of Inclusion -- 12. Two-Faced Janus: The Role of Peers in Adolescence -- Part IV. The Digital Era in Adolescent’s Health and Well-Being -- 13. Adolescence Between Past and Future -- 14. e-Health Strategies -- 15. Images and Perspectives of Play for Children’s and Adolescents’ Well-being -- 16. New Perspectives for Multidisciplinary and Integrated Strategies of Adolescent Health and Well-being.
- Format
- e-Book
- Location
- Online
Medical biochemistry
https://libcat.nshealth.ca/en/permalink/provcat32898
editors John W. Baynes, Marek H. Dominiczak.
(5th ed.)
--Edinburgh, Scotland:
Elsevier
, c2019.
- Available Online
- View e-Book
- Access
- Registration required for PDF access.
- Location
- Online
Now fully revised, this acclaimed textbook efficiently links basic biochemistry with the day-to-day practice of medicine. You will learn basic science concepts and see them illustrated by clinical cases that describe patients you will likely encounter in your clinical training. You will also learn about the use of laboratory tests to diagnose and monitor the most important conditions. Brought to you in a thorough yet accessible manner, this new edition of Medical Biochemistry highlights the la…
- Available Online
- View e-Book
- Other Authors
- Baynes, John
- Dominiczak, Marek H
- Responsibility
- editors John W. Baynes, Marek H. Dominiczak
- Edition
- 5th ed.
- Alternate Title
- Biochemistry
- Place of Publication
- Edinburgh, Scotland
- Publisher
- Elsevier
- Date of Publication
- c2019
- Physical Description
- 1 online resource, 712 p.
- ISBN
- 9780702072994
- Subjects (MeSH)
- Biochemical Phenomena
- Biochemistry - methods
- Specialty
- Biochemistry
- Abstract
- Now fully revised, this acclaimed textbook efficiently links basic biochemistry with the day-to-day practice of medicine. You will learn basic science concepts and see them illustrated by clinical cases that describe patients you will likely encounter in your clinical training. You will also learn about the use of laboratory tests to diagnose and monitor the most important conditions. Brought to you in a thorough yet accessible manner, this new edition of Medical Biochemistry highlights the latest developments in regulatory and molecular biology, signal transduction, biochemistry and biomarkers of chronic disease, and bioinformatics and the '-omics'. It highlights the most important global medical issues: diabetes mellitus, obesity and malnutrition, cancer and atherosclerotic cardiovascular disease, and addresses the role of nutrition and exercise in medicine.
- Access
- Registration required for PDF access.
- Format
- e-Book
- Location
- Online
Physiology of the gastrointestinal tract
https://libcat.nshealth.ca/en/permalink/provcat42115
editor in chief Hamid Said.
(3rd ed.)
--London, UK:
Elsevier
, c2018.
- Available Online
- View e-Book
- Access
- Registration required for PDF access.
- Location
- Online
Physiology of the Gastrointestinal Tract, Sixth Edition, a Two-Volume set, covers the study of the mechanical, physical and biochemical functions of the GI Tract by linking clinical disease and disorder, thus bridging the gap between clinical and laboratory medicine while also covering breakthroughs in gastroenterology, such as the brain-gut axis and microbiome. Additionally, information is provided at the organism level, including animal models of gastrointestinal disorders and therapeutic po…
- Available Online
- View e-Book
- Other Authors
- Said, Hamid
- Responsibility
- editor in chief Hamid Said
- Edition
- 3rd ed.
- Place of Publication
- London, UK
- Publisher
- Elsevier
- Date of Publication
- c2018
- Physical Description
- 1 online resource, 1812 p.
- ISBN
- 9780128099544
- Subjects (MeSH)
- Gastrointestinal Tract - physiology
- Subjects (LCSH)
- Gastrointestinal system
- Specialty
- Gastroenterology
- Physiology
- Abstract
- Physiology of the Gastrointestinal Tract, Sixth Edition, a Two-Volume set, covers the study of the mechanical, physical and biochemical functions of the GI Tract by linking clinical disease and disorder, thus bridging the gap between clinical and laboratory medicine while also covering breakthroughs in gastroenterology, such as the brain-gut axis and microbiome. Additionally, information is provided at the organism level, including animal models of gastrointestinal disorders and therapeutic possibilities. The book covers a wide range of conditions, from food allergies, constipation, chronic liver disease and IBS, also exploring emerging techniques to diagnose and normalize functions of the GI tract.
- Access
- Registration required for PDF access.
- Format
- e-Book
- Location
- Online
Neonatology : A Practical Approach to Neonatal Diseases
https://libcat.nshealth.ca/en/permalink/provcat42557
Giuseppe Buonocore, Rodolfo Bracci, Michael Weindling, editors.
(Second edition)
--Cham:
Springer
, c2018.
- Available Online
- View e-Book
- Location
- Online
This landmark book, a reference work now in its second edition, provides healthcare practitioners in neonatology with an up-to-date, comprehensive source of readily accessible practical advice that will assist in the expert management of patients and their diverse illnesses. Leading experts in their fields discuss the underlying causes and mechanisms and all aspects of the treatment of the full range of neonatal diseases and abnormalities, citing the evidence base whenever appropriate. In addit…
- Available Online
- View e-Book
- Other Authors
- Buonocore, Giuseppe
- Bracci, Rodolfo
- Weindling, Michael
- Responsibility
- Giuseppe Buonocore, Rodolfo Bracci, Michael Weindling, editors
- Edition
- Second edition
- Place of Publication
- Cham
- Publisher
- Springer
- Date of Publication
- c2018
- Physical Description
- 1 online resource (xiii, 2528 p.) : 568 illus., 358 illus. in color
- Series Title
- Springer reference
- ISBN
- 9783319294896
- 9783319294872 (print ed.)
- Subjects (MeSH)
- Infant, Newborn, Diseases
- Neonatology
- Specialty
- Neonatology
- Notes
- "eReference"--Publisher.
- Abstract
- This landmark book, a reference work now in its second edition, provides healthcare practitioners in neonatology with an up-to-date, comprehensive source of readily accessible practical advice that will assist in the expert management of patients and their diverse illnesses. Leading experts in their fields discuss the underlying causes and mechanisms and all aspects of the treatment of the full range of neonatal diseases and abnormalities, citing the evidence base whenever appropriate. In addition, detailed information is provided on epidemiology and fetal medicine; therapeutic issues such as the organization of care, transport services, and home care after discharge; legal issues; nutrition; and the consequences of medication use during pregnancy, maternal drug abuse and smoking, and maternal diabetes. The inclusion of summaries, tables, and carefully selected guidelines and recommendations will supply practitioners with quick references and instant solutions during daily practice. The book will be a superb resource for all involved in the care of newborn babies, including neonatologists, pediatricians, pediatric surgeons, anesthesiologists, midwives, and nursing staff. It is published within the SpringerReference program, which delivers access to living editions constantly updated through a dynamic peer-review publishing process.
- Contents
- Acute and Chronic Renal Failure in the Newborn Infant -- Anemia in the Neonatal Period -- Apnea of Prematurity and Sudden Infant Death Syndrome -- Bilirubin Metabolism, Unconjugated Hyperbilirubinemia, and Physiologic Neonatal Jaundice -- Biochemical Basis of Hypoxic-Ischemic Encephalopathy -- Blood Pressure Disorders in the Neonate: Hypotension and Hypertension -- Brain Development and Perinatal Vulnerability to Cerebral Damage -- Bronchopulmonary Dysplasia/Chronic Lung Disease of the Newborn -- Calcium and Phosphorus Homeostasis of Newborns: Pathophysiology -- Cardiac Emergencies in the Newborn -- Cardiovascular Physiology, Pathology, and Clinical Investigation in Neonatal Medicine -- Care of Extremely Low Birth Weight Infants and Timing of Discharge. Information and Psychosocial Intervention in Neonatology. -- Cerebral Hemorrhage in Newborns -- Cerebral Plasticity and Functional Reorganization in Children with Congenital Brain Lesions -- Clinical Aspects and Treatment of the Hypoxic-Ischemic Syndrome -- Coagulation Disorders in Newborns: Clinical Aspects of Platelet Disorders -- Congenital Immunodeficiencies in Newborns -- Congenital Malformations and Syndromes: Early Diagnosis and Prognosis in Neonatal Medicine -- Congenital Malformations of the Brain: Prenatal Diagnosis, Spectrum and Causes -- Continuous Positive Airways Pressure and other Non-Invasive Ventilation Techniques in Newborns -- Control of Breathing in Newborns -- Creactive Protein and Procalcitonin: Reference Intervals in Term and Preterm Newborns -- Development and General Characteristics of Preterm and Term Newborn -- Developmental Pharmacology and Therapeutics in Neonatal Medicine -- Diagnosis and Treatment of Renal and Urinary Tract Malformations in Newborns -- Diagnosis of Fetal Distress -- Disorders of Sexual Development in Newborns -- Early Detection of Neonatal Depression and Asphyxia -- Early Diagnosis of Congenital Heart Disease: When and How to Treat -- Early Markers of Poor Outcome in Neonatal Medicine -- Endocrine Diseases and Disorders of Thyroid Function in Newborns -- Enteral Feeding of the Very Low Birth Weight Infant -- Environment and Early Developmental Care for Newborns -- Epidemiology of Adverse Cerebral Outcome of Newborns -- Epidemiology: Mortality, Morbidity and Follow Up of High Risk Newborns -- Epigenetic Mechanisms -- Esophageal Atresia of Newborns -- Ethical Problems in Neonatal Medicine -- Extracorporeal Membrane Oxygenation for Neonates -- Feeding the Term Infant: Human Milk and Formulas -- Fetal and Neonatal Hydrops -- Fetal Infections: Congenital Syphilis and Tuberculosis -- Fetal Infections: Cytomegalovirus, Herpes Simplex, and Varicella -- Fetal infections: Rubella, HIV, HCV, HBV, and Human Parovirus B19 -- Follow-up Outcomes of High Risk Infants -- Fundamentals of Feto-Neonatal Immunology and Its Clinical Relevance -- Gastroenteritis and Intractable Diarrhea in Newborns -- Gastrointestinal Malformations of Newborns -- Guidelines and Protocols for Newborns -- Hematology and Immunology of Newborns: Overview -- Hirschsprung's Disease in Newborns -- Hormones and Gastrointestinal Function of Newborns -- Human Milk and Formulas for Neonatal Nutrition -- In Vitro Fertilization and Multiple Pregnancies -- Inborn Errors of Metabolism and Newborns -- Infants of Diabetic Mothers -- Infants of Smoking Mothers -- Inflammation and Perinatal Brain Injury -- Inflammatory Mediators in Neonatal Asphyxia and Infection -- Intrauterine Growth Restriction: Obstetric and Neonatal Aspects. Intervention Strategies. -- Kernicterus, Bilirubin-Induced Neurological Dysfunction, and New Treatments for Unconjugated Hyperbilirubinemia in Neonates -- Laboratory Medicine: Reference Intervals for Laboratory Tests and Procedures -- Laboratory Medicine: Reference Values and Evidence Based Medicine -- Late Preterm Infants at Risk for Short-Term and Long Term Morbidity and Mortality -- Lung Diseases: Problems of Steroid Treatment of Fetus and Newborn -- Lung Diseases: Surfactant Replacement Therapy in Newborns -- Lung Ultrasounds in Neonatal Diagnostic -- Malformations of Cortical Development in Newborns: Genetic Aspects -- Meconium Aspiration Syndrome -- Meconium Plug Syndrome -- Micronutrients and Vitamins of Newborns -- Molecular Structure of Surfactant: Biochemical Aspects in Newborns -- Necrotizing Enterocolitis of Newborns -- Neonatal Anesthesia -- Neonatal Bacterial and Fungal Infections -- Neonatal Care in the Delivery Room: Initial Management and Approach To Low Risk Newborns -- Neonatal Cholestasis-Conjugated Hyperbilirubinemia -- Neonatal Electroencephalography -- Neonatal Hereditary Neutropenia -- Neonatal Lung Development and Pulmonary Malformations -- Neonatal Malignancies -- Neonatal Orthopedic Surgery -- Neonatal Pain: Neurophysiology, Recognition, Prevention and Management with Non-Pharmacological Interventions -- Neonatal Pulmonary Physiology of Term and Preterm Newborns -- Neonatal Seizuresá -- Neonatal Septic Shock -- Neonatal Skin Disorders -- Neonatal Stroke: Clinical Presentation, Imaging, Treatment, and Prognosis -- Neonatal Stroke: Mechanisms -- Neonatal Transport Services -- Neonatal Viral Infections: Enteroviruses and Respiratory Syncytial Virus -- Neonatology and the Law -- Neuroimaging Studies of Newborns -- Neurological Examination of the Newborn Infantá -- Neuromuscular Disorders in Newborns -- Neuroprotective Strategies for Newborns -- Normal and Abnormal Neurodevelopmental and Behavioral Outcomes of Very Low-Birth Weight (VLBW) Infants -- Nutritional Recommendations for the Very Low Birth Weight Newborn -- Ocular Malformations in Newborns -- Organization of Perinatal Care. Training of Doctors and Nurses -- Orofacial Malformations -- Oxygen Saturation Monitoring in Neonatal Period -- Oxygen Toxicity in Newborns -- Parenteral Nutrition of Newborns -- Patent Ductus Arteriosus in Newborns -- Pathologic Unconjugated Hyperbilirubinemia, Isoimmunization, Abnormalities of Red Blood Cells, and Infections -- Pathology and Treatment of Liver Diseases in Newborns -- Pathophysiology of Coagulation and Deficiencies of Coagulation Factors in Newborns -- Pathophysiology of Fetal and Neonatal Kidneys -- Persistent Pulmonary Hypertension of the Newborn and Congenital Diaphragmatic Hernia: Nitric Oxide Therapy in Neonatology -- Physical Environment for Newborns: the Thermal Environment -- Physical Examination of the Newborn -- Physiology and Abnormalities of Leukocytes in Newborns -- Physiology of the Gastrointestinal Tract in Newborns -- Polycythemia and Hyperviscosity in Neonates -- Post-Discharge Nutrition in Preterm Infants -- Prenatal and Postnatal Inflammatory Mechanisms -- Primary Investigations in the Term and Preterm Newborn -- Problems of Discharge and Home Care of Newborns -- Pulmonary Air Leakage in Newborns -- Pulmonary Hemorrhage, Transient Tachypnea and Neonatal Pneumonia -- Quality of Neonatal Intensive Care and Outcome for High Risk Newborn Infants -- Rare Lung Diseases of Newborns -- Rare Surgical Emergencies of Newborns -- Recombinant G-CSF Treatment of Severe Chronic Neutropenia in Neonates and Infants -- Rehydration after Diarrhea in Newborns -- Respiratory Distress Syndrome: Predisposing Factors, Pathophysiology, and Diagnosis -- Resuscitation of the Newborn -- Retinopathy of Prematurity -- Risk Factors for Gestational Diseases -- Risk Management of Newborns -- Safety of Medications During Pregnancy and Breastfeeding: Infants of Drug-Addicted Mothers -- Surfactant Metabolism in Neonatal Lung Diseases -- Surgical Treatment in Newborns of Necrotizing Enterocolitis -- Surgical Treatment of Biliary Tract Malformations in Newborns -- The Fetus at Risk: Chorioamnionitis -- The Process of Decision-Making in Neonatology -- The Thrombotic Risk of the Newborn -- The Timing of Neonatal Brain Damage -- Toxoplasmosis in the Fetus and in the Newborn -- Treatment of Hyperbilirubinemia in Newborns -- Treatment of Respiratory Failure in Newborn: Mechanical Ventilation -- Vaccinations and Neonatal Immunity.
- Format
- e-Book
- Location
- Online
Pediatric Obesity : Etiology, Pathogenesis and Treatment
https://libcat.nshealth.ca/en/permalink/provcat42798
Michael S. Freemark, editor.
(Second edition)
--Cham:
Humana Press
, c2018.
- Available Online
- View e-Book
- Location
- Online
This second edition of Freemark's text embodies all of the strengths of the original work but is deeper and broader in scope, with new chapters on emerging themes including metabolomics, genomics, and the roles of gastrointestinal hormones, the microbiome, brown adipose tissue, and endocrine disruptors in the pathogenesis of childhood obesity. Reviews of the effects of weight excess on cognitive performance and immune function complement detailed analyses of the biochemical and molecular pathwa…
- Available Online
- View e-Book
- Other Authors
- Freemark, Michael S.
- Responsibility
- Michael S. Freemark, editor
- Edition
- Second edition
- Place of Publication
- Cham
- Publisher
- Humana Press
- Date of Publication
- c2018
- Physical Description
- 1 online resource (xxv, 814 p.) : 109 illus., 91 illus. in color
- Series Title
- Contemporary endocrinology
- ISBN
- 9783319681924
- 9783319681917 (print ed.)
- 9783319681931 (print ed.)
- 9783319885605 (print ed.)
- ISSN
- 2523-3785
- Subjects (MeSH)
- Adolescent
- Child
- Pediatric Obesity - etiology
- Pediatric Obesity - therapy
- Specialty
- Bariatric Medicine
- Pediatrics
- Abstract
- This second edition of Freemark's text embodies all of the strengths of the original work but is deeper and broader in scope, with new chapters on emerging themes including metabolomics, genomics, and the roles of gastrointestinal hormones, the microbiome, brown adipose tissue, and endocrine disruptors in the pathogenesis of childhood obesity. Reviews of the effects of weight excess on cognitive performance and immune function complement detailed analyses of the biochemical and molecular pathways controlling the development of childhood adiposity and metabolic disease. Critical assessments of nutritional interventions (including new chapters on infant feeding practices and vegetarian diets) and superb reviews of behavioral counseling, pharmacotherapy, and bariatric surgery provide practical guidance for the management of overweight children. Penetrating analyses of the obesity epidemic in its social, cultural, economic, and political contexts highlight challenges and opportunities for obesity prevention and community action. The perspective is international in scope and reflects the expertise and experience of many of the leading figures in the field. Comprehensive and up-to-date, this new edition of Pediatric Obesity: Etiology, Pathogenesis and Treatment will be an invaluable guide for all healthcare providers and policy makers concerned with the evaluation and care of children with nutritional and metabolic disease and with the societal implications of the obesity epidemic.
- Contents
- I. The Obesity Epidemic: A Global Perspective -- Global Dynamics in Childhood Obesity: Reflections on a Life of Work in the Field -- Childhood Malnutrition and the Origins of Obesity in the Developing World -- II. Hormonal and Metabolic Control of Appetite, Fat Deposition and Energy Expenditure -- The Neuroendocrine Control of Energy Balance -- GI Hormones and the Control of Food Intake -- The Microbiome and Control of Weight Gain -- III. Adipocyte Development and Function in Obesity and IR -- Control of White Adipose Tissue Development and Function in Obesity: Preclinical Models -- White Adipose Distribution and Function in Healthy and Obese Children -- Brown and Beige Fat: Development, Regulation and Function -- IV. The Genetics of Childhood Obesity -- Monogenic Obesity -- Syndromic Obesity -- Polygenic Obesity -- Racial Differences in Childhood Obesity: Pathogenesis and Complications -- V. Pre- and Perinatal Determinants of Childhood Obes ity -- Maternal Determinants of Childhood Obesity: Weight Gain, Smoking, and Breastfeeding -- Intrauterine Growth Retardation -- Gestational Diabetes -- Endocrine Disruptors as Obesogens -- VI. The Role of Diet and Energy Expenditure in Obesity Pathogenesis -- Early Childhood Feeding Practices and Development of Childhood Obesity -- Macronutrients in the Development, Treatment and Prevention of Obesity: Two Views -- Carbohydrates and the Glycemic Index -- Caloric Intake, Caloric Density, and Fiber -- Energy Expenditure in Children: The Role of NEAT -- VII. Metabolic Complications of Childhood Obesity -- Childhood Obesity and the Regulation of Growth, Thyroid Function, Sexual Development and Calcium Homeostasis -- Metabolic Signatures in Childhood Obesity -- Pathogenesis of Insulin Resistance and Glucose Intolerance in Childhood Obesity -- Type 2 Diabetes in Children -- Pathogenesis and Management of Dyslipidemia in Obese Children -- Fatty Liver Disease -- Pathogenesis of Hypertension and Renal Disease in Obesity -- Sleep-Disordered Breathing and Sleep Duration in Childhood Obesity -- The Long-Term Metabolic Complications of Childhood Obesity -- Childhood Obesity, Atherogenesis and Adult Cardiovascular Disease -- Childhood Obesity and Cognitive Function -- VIII. Treatment of Childhood Obesity: Lifestyle Intervention -- Family-Based Behavioral Interventions -- Exercise and Childhood Obesity -- School- and Community-Based Interventions -- IX. Pharmacotherapy and Bariatric Surgery for Obesity and Co-morbidities -- Pharmacotherapy of Childhood Obesity and Pre-Diabetes -- Pathogenesis and Management of Adiposity and Insulin Resistance in PCOS -- Obesity and Metabolic Dysfunction in the Child with a Major Behavioral Disorder: Atypical Antipsychotics -- Hypothalamic Obesity -- Bariatric Surgery in Adolescents -- X. Challenges to Long-Term Success -- Neuroendocrine and Metabolic Adaptations in the Central Nervous System that Facilitate Weight Regain -- The Sociocultural Context for Obesity Prevention and Treatment in Children and Adolescents: Influences of Ethnicity and Gender -- XI. The Future of Childhood Obesity in the Global Marketplace -- The Marketing and Distribution of Fast Food -- Local and National Policy-Based Interventions: To Improve Children's Nutrition.
- Format
- e-Book
- Location
- Online
Prostate Cancer : Clinical Case Scenarios
https://libcat.nshealth.ca/en/permalink/provcat42950
edited by Sam S. Chang, Michael S. Cookson.
--Cham, Switzerland:
Springer
, c2018.
- Available Online
- View e-Book
- Location
- Online
This book provides a single, comprehensive reference source that incorporates all the latest information regarding prostate cancer. It serves as an easy reference source for researchers, clinicians, individuals in training, allied health professionals and medical students regarding prostate cancer by focusing on the controversial points of debate. New data regarding PSA screening, prostate cancer biomarkers, diagnostic evaluation techniques, surveillance protocols, and treatment interventions f…
- Available Online
- View e-Book
- Other Authors
- Chang, Sam S.
- Cookson, Michael S.
- Responsibility
- edited by Sam S. Chang, Michael S. Cookson
- Place of Publication
- Cham, Switzerland
- Publisher
- Springer
- Date of Publication
- c2018
- Physical Description
- 1 online resource (xiii, 202 p.) : 15 illus., 10 illus. in color
- ISBN
- 9783319786469
- 9783319786452 (print ed.)
- 9783319786476 (print ed.)
- Subjects (MeSH)
- Prostatic Neoplasms
- Specialty
- Medical Oncology
- Urology
- Abstract
- This book provides a single, comprehensive reference source that incorporates all the latest information regarding prostate cancer. It serves as an easy reference source for researchers, clinicians, individuals in training, allied health professionals and medical students regarding prostate cancer by focusing on the controversial points of debate. New data regarding PSA screening, prostate cancer biomarkers, diagnostic evaluation techniques, surveillance protocols, and treatment interventions for localized and more advanced disease are discussed, and gaps in current knowledge and areas for future research are highlighted. Ongoing important clinical trials are also discussed. This text is organized around defined clinical scenarios which are encountered routinely by physicians who care for patients with prostate cancer. The case based format permits presentation of information of concise practical significance. The chapters run the gamut from screening controversies, utility of biomarkers, surveillance strategies, and innovative treatment. The text incorporates key educational concepts in the framework of patient situations with evidence-based discussions of screening, diagnosis, evaluation, and therapeutic management. It also features a comment section from leaders in the field that will be more "opinion-based" allowing the reader to get access to experienced physicians' thought processes and practice patterns. Prostate Cancer: Clinical Case Scenarios will quickly become the ready reference source for professionals and students in various fields with an interest in the management of a complex and multifaceted disease such as prostate cancer.
- Contents
- Prostate Cancer Screening in African-American Men -- Evaluation and Treatment for Older Men with Elevated PSA -- Utilizing Biomarkers in Patients with Prior Negative Prostate Biopsy -- Active Surveillance in African-Americans -- Focal Therapy versus Surveillance in Intermediate Risk Cancer -- Prostate Cancer Treatment Options for Men with Significant Urinary Symptoms and Enlarged Prostates -- Adjuvant Radiation Therapy for High Risk Post Prostatectomy Patients -- Biochemical Recurrence after Radiation Therapy -- Options After Chemotherapy for Patients with Metastatic, Castration-Resistant Prostate Cancer -- Evaluation and Treatment for High-Risk Prostate Cancer -- High Intensity Focused Ultrasound (HIFU) Options for High-Risk Prostate Cancer -- Radical Prostatectomy in the Metastatic Setting -- Resection of Metastatic Cancer in Castration-Resistant Patients.
- Format
- e-Book
- Location
- Online
Atlas of Thyroid and Neuroendocrine Tumor Markers
https://libcat.nshealth.ca/en/permalink/provcat43325
Luca Giovanella, editor.
--Cham:
Springer
, c2018.
- Available Online
- View e-Book
- Location
- Online
This book highlights the increase in thyroid tumors and NET and demonstrates the growing importance of circulating markers in diagnosis as well as treatment and follow-up. Dramatic technical improvements have heightened the clinical impact of well-established, conventional biochemical markers. In addition, more recent genetic and molecular approaches have provided innovative molecular markers. In this context, effective communication between clinicians and laboratory physicians/scientists is es…
- Available Online
- View e-Book
- Other Authors
- Giovanella, Luca
- Responsibility
- Luca Giovanella, editor
- Place of Publication
- Cham
- Publisher
- Springer
- Date of Publication
- c2018
- Physical Description
- 1 online resource (xii, 249 p.) : 41 illus., 30 illus. in color
- ISBN
- 9783319625065
- 9783319625058 (print ed.)
- 9783319625072 (print ed.)
- 9783319873305 (print ed.)
- Subjects (MeSH)
- Biomarkers, Tumor
- Neuroendocrine Tumors - diagnosis
- Neuroendocrine Tumors - therapy
- Thyroid Neoplasms - diagnosis
- Thyroid Neoplasms - therapy
- Specialty
- Endocrinology
- Medical Oncology
- Abstract
- This book highlights the increase in thyroid tumors and NET and demonstrates the growing importance of circulating markers in diagnosis as well as treatment and follow-up. Dramatic technical improvements have heightened the clinical impact of well-established, conventional biochemical markers. In addition, more recent genetic and molecular approaches have provided innovative molecular markers. In this context, effective communication between clinicians and laboratory physicians/scientists is essential in allowing all those involved to fully profit from these exciting advances. In this comprehensive, up-to-date book, authors from different laboratory and clinical areas link laboratory and clinical topics. Analytical problems such as interferences, false-negative and false-positive results are discussed in depth, and flow-charts offer insights into identifying and avoiding them. Illustrated clinical cases detail the clinical role and limitations of different tumor markers. Lastly, it explores health technology assessment and economic issues. This is a valuable resource for endocrinologists, oncologists, nuclear medicine physicians, scientists and technologists who want to keep abreast of the latest developments.
- Contents
- Part I. Pathology and Pathobiology -- 1. Pathology and Immunohistochemistry in Thyroid Tumors -- 2. Pathology of Neuroendocrine Neoplasms: Morphological, Immunophenotypical, and Circulating Molecular Markers -- 3. Circulating Biomarkers: Biological Basis, Methods, and Interpretation Criteria -- Part II. Differentiated Thyroid Cancer -- 4. Differentiated Thyroid Cancer: Diagnosis, Therapy, and Follow-Up -- 5. Thyroglobulin and Thyroglobulin Antibodies -- 6. Circulating Molecular Biomarkers in Thyroid Cancer -- 7. Circulating Epithelial Tumor Cells in Thyroid Carcinoma -- Part III. Medullary Thyroid Carcinoma -- 8. Medullary Thyroid Carcinoma (MTC): Diagnosis, Treatment and Follow-Up -- 9. Calcitonin and Carcinoembryonic Antigen for the Diagnosis and Management of Medullary Thyroid Carcinoma -- 10. Procalcitonin: Are We Ready for Clinical Use? -- Part IV. Aggressive and Rare Thyroid Carcinoma -- 11. Aggressive Variants of Thyroid Carcinoma -- 12. Circulating Mucins and Cytokeratins in Aggressive Thyroid Cancers -- Part V. Thyroid Biomarkers on Fine-Needle Washouts -- 13. Measurement of Thyroid Tumor Markers on Fine-Needle Washouts -- Part VI. Neuroendocrine Tumors -- 14. Neuroendocrine Tumours: Diagnosis, Therapy and Follow-up -- 15. Circulating Markers in Neuroendocrine Tumors -- 16. Neuroendocrine Gene Transcripts: The Role of Molecular Biomarkers in Diagnosis and Management.
- Format
- e-Book
- Publication Type
- Atlas
- Location
- Online
Medical biochemistry Q&A
https://libcat.nshealth.ca/en/permalink/provcat45148
Joseph D. Fontes, Darla L. McCarthy.
--New York, NY:
Thieme
, c2018.
- Available Online
- View e-Book
- Location
- Online
- Available Online
- View e-Book
- Author
- Fontes, Joseph D.
- Other Authors
- McCarthy, Darla L.
- Responsibility
- Joseph D. Fontes, Darla L. McCarthy
- Alternate Title
- Thieme test prep for the USMLE® - medical biochemistry Q&A
- Medical biochemistry Q & A
- Medical biochemistry questions and answers
- Medical biochemistry questions & answers
- Place of Publication
- New York, NY
- Publisher
- Thieme
- Date of Publication
- c2018
- Physical Description
- 1 online resource
- Series
- Thieme test prep for the USMLE
- ISBN
- 9781626234635
- Subjects (MeSH)
- Biochemical Phenomena
- Specialty
- Biochemistry
- Format
- e-Book
- Publication Type
- Case Reports
- Examination Questions
- Location
- Online
Human biochemistry
https://libcat.nshealth.ca/en/permalink/provcat50811
Litwack, Gerald.
(1st ed.)
--Philadelphia, PA:
Elsevier
, 2018.
- Available Online
- View e-Book
- Location
- Online
- Available Online
- View e-Book
- Author
- Litwack, Gerald
- Edition
- 1st ed.
- Place of Publication
- Philadelphia, PA
- Publisher
- Elsevier
- Date of Publication
- 2018
- ISBN
- 9780123838643
- Subjects (MeSH)
- Biochemical Phenomena
- Biological Phenomena
- Clinical Medicine
- Disease
- Notes
- Access to this online resource is restricted to IWK Health Centre employees working from inside the hospital network.
- Format
- e-Book
- Location
- Online
Atlas of Genetic Diagnosis and Counseling
https://libcat.nshealth.ca/en/permalink/provcat41222
Harold Chen.
(Third edition)
--New York, NY:
Springer
, 2017.
- Available Online
- View e-Book
- Location
- Online
Dr. Harold Chen shares his almost 50 years of clinical genetics practice in this new edition of a comprehensive pictorial atlas, featuring almost 290 genetic disorders, malformations, and malformation syndromes. The author provides a detailed outline for each disorder, describing its genetics, basic defects, clinical features, diagnostic tests, and counseling issues, including recurrence risk, prenatal diagnosis, and management. Numerous color photographs of prenatal ultrasounds, imagings, cyto…
- Available Online
- View e-Book
- Author
- Chen, Harold
- Responsibility
- Harold Chen
- Edition
- Third edition
- Place of Publication
- New York, NY
- Publisher
- Springer
- Date of Publication
- 2017
- Physical Description
- 1 online resource (xxiii, 3080 pages) : 1242 illus., 1050 illus. in color
- Series Title
- Springer reference
- ISBN
- 9781493924011
- 9781493924004 (print ed.)
- Subjects (MeSH)
- Genetic Counseling
- Genetic Diseases, Inborn
- Prenatal Diagnosis
- Abstract
- Dr. Harold Chen shares his almost 50 years of clinical genetics practice in this new edition of a comprehensive pictorial atlas, featuring almost 290 genetic disorders, malformations, and malformation syndromes. The author provides a detailed outline for each disorder, describing its genetics, basic defects, clinical features, diagnostic tests, and counseling issues, including recurrence risk, prenatal diagnosis, and management. Numerous color photographs of prenatal ultrasounds, imagings, cytogenetics, and postmortem findings illustrate the clinical features of patients at different ages, patients with varying degrees of severity, and the optimal diagnostic strategies. The disorders cited are supplemented by case histories and diagnostic confirmation by cytogenetics, biochemical, and molecular techniques, when available. Since the publication of the previous edition in 2012, the atlas has been widely accepted and used in light of rapid progress in genetic and gnomic information. In this new edition, additional genetic disorders are added, as well as extensive updates to the previous disorders with new illustrations, supplemented by case and family history, clinical features, and laboratory data, especially molecular confirmation if available. The atlas is written in outline format for ease of use. Atlas of Genetic Diagnosis and Counseling, Third Edition is of great value to medical geneticists, genetic counselors, pediatricians, neonatologists, developmental pediatricians, perinatologists, obstetricians, neurologists, pathologists, and any physicians and health care professionals caring for handicapped children such as craniofacial surgeons, plastic surgeons, otolaryngologists, and orthopedists. It is the definitive volume for helping all physicians to understand and recognize genetic diseases and malformation syndrom es and better evaluate, counsel, and manage affected patients.
- Contents
- Acardia -- Achondrogenesis -- Achondroplasia -- Adams-Oliver Syndrome -- Agnathia -- Aicardi Syndrome -- Alagille Syndrome -- Albinism -- Alpha-Thalassemia X-linked Mental Retardation Syndrome -- Ambiguous Genitalia -- Amniotic Deformity, Adhesions, Mutilations (ADAM) Complex -- Androgen Insensitivity Syndrome -- Angelman Syndrome -- Apert Syndrome -- Aplasia Cutis Congenita -- Arthrogryposis Multiplex Congenita -- Asphyxiating Thoracic Dystrophy -- Ataxia-Telangiectasia -- Atelosteogenesis -- Autism -- Bannayan-Riley-Ruvalcaba Syndrome -- Beckwith-Wiedemann Syndrome -- Behcet Disease -- Biotinidase Deficiency -- Bladder Exstrophy -- Blepharophimosis, Ptosis, and Epicanthus Inversus Syndrome -- Body Stalk Anomaly -- Brachydactyly -- Branchial Cleft Anomalies -- Calcinosis Cutis -- Campomelic Dysplasia -- Carpenter Syndrome -- Cat Eye Syndrome -- Celiac Disease -- Cerebral Palsy -- Cerebro-Costo-Mandibular Syndrome -- Charcot-Marie-Tooth Disease -- CHARGE Syndrome -- Cherubism -- Chiari Malformation -- Chondrodysplasia Punctata -- Chromosome Abnormalities in Pediatric Solid Tumors -- Cleft Lip and/or Cleft Palate -- Cleidocranial Dysplasia -- Cloacal Exstrophy -- Clubfoot -- Collodion Baby -- Congenital Adrenal Hyperplasia -- Congenital Cutis Laxa -- Congenital Cytomegalovirus Infection -- Congenital Generalized Lipodystrophy -- Congenital Hemihyperplasia -- Congenital Hydrocephalus -- Congenital Hypothyroidism -- Congenital Muscular Dystrophy -- Congenital Toxoplasmosis -- Conjoined Twins -- Corpus Callosum Agenesis/Dysgenesis -- Craniometaphyseal Dysplasia -- Cri-Du-Chat Syndrome -- Crouzon Syndrome -- Cutaneous Vasculitis -- Cutis Marmorata Telangiectatica Congenita -- Cystic Fibrosis -- Dandy-Walker Malformation -- De Lange Syndrome -- Del(18p) Syndrome -- Del(22q11.2) Syndrome -- Del(Yq) Syndrome -- Diabetic Embryopathy -- Down Syndrome -- Duncan Syndrome -- Dyschondrosteosis -- Dysmelia -- Dysplasia Epiphysealis Hemimelica -- Dystonia -- Dystrophinopathies -- Ectrodactyly-Ectodermal Dysplasia-Clefting (EEC) Syndrome -- Ehlers-Danlos Syndrome -- Ellis-van Creveld Syndrome -- Enchondromatosis -- Epidermolysis Bullosa -- Epidermolytic Palmoplantar Keratoderma -- Faciogenital (Faciodigitogenital) Dysplasia -- Facioscapulohumeral Muscular Dystrophy -- Familial Adenomatous Polyposis -- Familial Hyperlysinemia -- Familial Mediterranean Fever -- Familial Patella Instability -- Familial Spastic Paraplegia -- Fanconi Anemia -- Feingold Syndrome -- Femoral Hypoplasia - Unusual Facies Syndrome -- Fetal Akinesia Deformation Sequence -- Fetal Alcohol Spectrum Disorders -- Fetal Hydantoin Syndrome -- Fibrodysplasia Ossificans Progressiva -- Fibular Hemimelia -- Finlay-Marks Syndrome -- Floppy Infant -- Fragile X Syndrome -- Fraser Syndrome -- Freeman-Sheldon Syndrome -- Friedreich Ataxia -- Frontonasal Dysplasia -- Galactosemia -- Gastroschisis -- Gaucher Disease -- Generalized Arterial Calcification of Infancy -- Genitopatellar Syndrome -- Giant Congenital Melanocytic Nevi -- Gilbert Syndrome -- Glucose-6-Phosphate Dehydrogenase Deficiency -- Glycogen Storage Disease, Type 2 -- Goldenhar Syndrome -- Gorlin Syndrome -- Greig Cephalopolysyndactyly Syndrome -- Growth Hormone Deficiency -- Hallermann-Streiff Syndrome -- Harlequin Ichthyosis -- Hemangiomas of Infancy -- Hemophilia A -- Hereditary Hearing Loss -- Hereditary -- Hemochromatosis -- Hereditary Multiple Exostoses -- Hereditary Sensory and Autonomic Neuropathies -- Herlyn-Werner-Wunderlich Syndrome -- Holoprosencephaly -- Holt-Oram Syndrome -- Huntington Disease -- Hydranencephaly -- Hydrolethalus Syndrome -- Hydrops Fetalis -- Hyper-IgE Syndrome -- Hypertrophic Cardiomyopathy (HCM) -- Hypochondroplasia -- Hypoglossia-Hypodactylia Syndrome -- Hypohidrotic Ectodermal Dysplasia -- Hypomelanosis of Ito -- Hypophosphatasia -- Hypopituitarism -- I(1p), I(1q) Syndrome -- Idic(Yq) Syndrome -- Incontinentia Pigmenti -- Infantile Myofibromatosis -- Ivemark Syndrome -- Jarcho-Levin Syndrome -- Joubert Syndrome -- Kabuki Syndrome -- Kasabach-Merritt Syndrome -- KID Syndrome -- Klinefelter Syndrome -- Klippel-Feil Syndrome -- Klippel-Trenaunay Syndrome -- Kniest Dysplasia -- Larsen Syndrome -- LEOPARD Syndrome -- Lesch-Nyhan Syndrome -- Lethal Multiple Pterygium Syndrome -- Loeys-Dietz Syndrome -- Lowe Syndrome -- Lymphangiomas and Lymphangiomatosis -- M#xf6;bius Syndrome -- Macrodactyly -- Marfan Syndrome -- McCune-Albright Syndrome -- Meckel-Gruber Syndrome -- Megalencephalic Leukoencephalopathy with Subcortical Cysts -- Menkes Disease -- Metachromatic Leukodystrophy -- Miller-Dieker Syndrome -- Mitochondrial Leber Hereditary Optic Neuropathy -- Mitochondrial Myopathy -- Mowat-Wilson Syndrome -- Mucolipidosis 2 -- Mucolipidosis 3 -- Mucopolysaccharidosis 1 (MPS 1) -- Mucopolysaccharidosis 2 -- Mucopolysaccharidosis 3 -- Mucopolysaccharidosis 4 -- Mucopolysaccharidosis 6 -- Multiple Endocrine Neoplasia Syndromes -- Multiple Epiphyseal Dysplasia -- Multiple Pterygium Syndrome -- Myotonic Dystrophy Type 1 -- Nager Acrofacial Dysostosis -- Nail-Patella Syndrome -- Nasal Obstruction in Neonates and Children -- Neonatal Herpes Simplex Infection -- Nephrogenic Diabetes Insipidus -- Netherton Syndrome -- Neu-Laxova Syndrome -- Neural Tube Defects -- Neurofibromatosis 1 -- Neurofibromatosis 2 -- Niemann-Pick Disease -- Noonan Syndrome -- Oblique Facial Cleft Syndrome -- Oligohydramnios Sequence -- Omphalocele -- Opitz Trigonocephaly (C) Syndrome -- Oral-Facial-Digital Syndrome -- Osteogenesis Imperfecta -- Osteogenesis Imperfecta Ehlers-Danlos Overlap Syndrome -- Osteopetrosis -- Osteopoikilosis -- Otopalatodigital Spectrum Disorders -- Pachyonychia Congenita -- Pallister-Killian Syndrome -- Peutz-Jeghers Syndrome -- Phenylketonuria -- Pierre Robin Sequence -- Polycystic Kidney Disease, Autosomal Dominant Type -- Polycystic Kidney Disease: Autosomal Recessive Type -- Popliteal Pterygium Syndrome -- Prader-Willi Syndrome -- Primary Microcephaly -- Progeria -- Prune Belly Syndrome -- Pseudoachondroplasia -- R(18) Syndrome -- Radioulnar Synostosis -- Retinoid Embryopathy -- Rett Syndrome -- Rickets -- Rigid Spine Syndrome -- Roberts Syndrome -- Robinow Syndrome -- Rubinstein-Taybi Syndrome -- Saethre-Chotzen Syndrome -- Sagittal Craniosynostosis Associated with Chromosome Abnormalities with a Brief Review on Craniosynostosis -- Schizencephaly Schmid Metaphyseal Chondrodysplasia -- Seckel Syndrome -- Severe Combined Immune Deficiency -- Short Rib-Polydactyly Syndromes -- Sickle Cell Disease -- Silver-Russell Syndrome -- Sirenomelia -- Smith-Lemli-Opitz Syndrome -- Smith-Magenis Syndrome -- Sotos Syndrome -- Spinal Muscular Atrophy -- Spondyloepiphyseal Dysplasia -- Stickler Syndrome -- Sturge-Webber Syndrome -- Symphalangism -- Tay-Sachs Disease -- Tetrasomy 9p Syndrome -- Thalassemia -- Thanatophoric Dysplasia -- Thrombocytopenia-Absent Radius Syndrome -- Treacher-Collins Syndrome -- Trimethylaminuria -- Triploidy -- Trismus-Pseudocamptodactyly Syndrome -- Trisomy 13 Syndrome -- Trisomy 18 Syndrome -- Trisomy 8 Mosaicism Syndrome -- Tuberous Sclerosis -- Turner Syndrome -- Twin-Twin Transfusion Syndrome -- Tyrosinemia -- Ulnar-Mammary Syndrome -- Urofacial Syndrome -- VATER (VACTERL) Association -- Von Hippel-Lindau Disease -- Waardenburg Syndrome -- Weill-Marchesani Syndrome -- Williams Syndrome -- Winchester syndrome -- Wolf-Hirschhorn Syndrome -- X-Linked Agammaglobulinemia -- X-Linked Ichthyosis -- XX Male -- XXX Syndrome -- XXXXX Syndrome -- XXXXY Syndrome -- XY Female -- XYY Syndrome.
- Format
- e-Book
- Publication Type
- Encyclopedia
- Location
- Online
Waldenström’s Macroglobulinemia
https://libcat.nshealth.ca/en/permalink/provcat41269
Véronique Leblond, Steve Treon, Meletios Dimoploulos, editors.
--Cham:
Springer
, 2017.
- Available Online
- View e-Book
- Location
- Online
This book sheds new light on clinical, biological and therapeutic data on the rare disease Waldenström’s Macroglobulinemia (WM) with the participation of widely-recognized experts, involved in this field. It represents the efforts of physicians, scientists and patients, all around the world, to better understand and cure this rare disease. Considerable advances in the diagnosis, treatment indications, response criteria, prognostic factors and treatment options have been made since Dr Jan Walden…
- Available Online
- View e-Book
- Other Authors
- Leblond, Véronique
- Treon, Steve
- Dimopoulos, Meletios
- Responsibility
- Véronique Leblond, Steve Treon, Meletios Dimoploulos, editors
- Place of Publication
- Cham
- Publisher
- Springer
- Date of Publication
- 2017
- Physical Description
- 1 online resource (ix, 377 pages) : 28 illus., 15 illus. in color
- ISBN
- 9783319225845
- 9783319225838 (print ed.)
- Subjects (MeSH)
- Waldenstrom Macroglobulinemia
- Notes
- The name of editor, Meletios Dimopoulos, is misspelled on the title page.
- Abstract
- This book sheds new light on clinical, biological and therapeutic data on the rare disease Waldenström’s Macroglobulinemia (WM) with the participation of widely-recognized experts, involved in this field. It represents the efforts of physicians, scientists and patients, all around the world, to better understand and cure this rare disease. Considerable advances in the diagnosis, treatment indications, response criteria, prognostic factors and treatment options have been made since Dr Jan Waldenström first reported this "new syndrome" 70 years ago. Particularly instrumental in advancing of our understanding of WM have been the eight international workshops devoted to this disease. New, exciting molecular data have recently been reported, allowing us to revisit the oncogenic events leading to WM B-cell proliferation and to use newly available compounds targeting oncogenic pathways.
- Contents
- Preface: Tribute to J Waldenström -- Part I: Tumor Cells and microenvironment -- Waldenström Macroglobulinaemia: Pathological Features and Diagnostic Assessment -- Waldenström’s Macroglobulinemia Immunophenotype -- Predispositions and Origins of Waldenstrom Macroglobulinemia: Implications from Genetic Analysis -- Cytogenetics in Waldenstr<©œm Macroglobulinemia (WM) -- Genetic and Signaling Abnormalities in Waldenström’s Macroglobulinemia -- Molecular Pathways in Growth and Survival: Epigenomics -- The Bone Marrow Microenvironment and Tumor Cells Interactions in Waldenström’s Macroglobulinemia -- Waldenström’s Macroglobulinaemia: Immunosurveillance and the Immune Micro-environment -- Part II: Epidemiology and Genetic Predisposition -- Epidemiology of Waldenström Macroglobulinemia -- Genetic Predisposition to Waldenström Macroglobulinemia -- Immunoglobulin Type M Monoclonal Gammopathy of Undetermined Significance (IgM-MGUS) -- Part III: Clinical Features -- Hyperviscosity Syndrome, Cold Agglutinin Hemolytic Anemia, and Cryoglobulinemia -- Neuropathy in Waldenström’s Macroglobulinaemia -- IgM Amyloidosis -- The Bing-Neel Syndrome -- Unusual Manifestations of IgM Monoclonal Gammopathies -- Part IV: Laboratory Investigations -- Laboratory Investigations and Findings: Hematological Abnormalities, Biochemical Investigations, Free Light and Heavy Chains -- Part V: Response -- Response Assessment in Waldenström’s Macroglobulinaemia -- Part VI: Prognostic Factors -- Risk Stratification in Waldenström Macroglobulinemia -- Part VII: Treatment Options and Recommendations -- Indications for Treatment of Waldenström’s Macroglobulinemia -- Immunotherapy in Waldenström’s Macroglobulinemia -- Immunomodulatory Agents and Proteasome Inhibitors in Waldenström’s Macroglobulinemia -- Signal Inhibitors in Waldenström’s Macroglobulinemia -- High-Dose Therapy and Haemopoietic Stem Cell Transplantation in Waldenström’s Macroglobulinaemia -- Long-Term Toxicity of Therapy in Waldenström Macroglobulinemia -- Treatment Recommendations in Waldenström Macroglobulinemia.
- Format
- e-Book
- Location
- Online
Integrative Cardiology : A New Therapeutic Vision
https://libcat.nshealth.ca/en/permalink/provcat41356
Massimo Fioranelli.
--Cham:
Springer
, 2017.
- Available Online
- View e-Book
- Location
- Online
This book is a detailed guide to a new integrative approach to the prevention and treatment of various cardiac disorders and risk factors, including coronary artery disease, congestive heart failure, arrhythmias, dyslipidemia, and hypertension. This approach combines various strategies, including metabolic cardiology, low-dose medicine, exercise programs, stress management programs, evaluation for inherited risk factors, and various other healing modalities. Metabolic cardiology focuses on the …
- Available Online
- View e-Book
- Other Authors
- Fioranelli, Massimo
- Responsibility
- Massimo Fioranelli
- Place of Publication
- Cham
- Publisher
- Springer
- Date of Publication
- 2017
- Physical Description
- 1 online resource (xii, 276 pages) : 63 illus., 59 illus. in color
- ISBN
- 9783319400105
- 9783319400082 (print ed.)
- Subjects (MeSH)
- Cardiovascular Diseases - prevention & control
- Cardiovascular Diseases - therapy
- Complementary Therapies - methods
- Integrative Medicine - methods
- Abstract
- This book is a detailed guide to a new integrative approach to the prevention and treatment of various cardiac disorders and risk factors, including coronary artery disease, congestive heart failure, arrhythmias, dyslipidemia, and hypertension. This approach combines various strategies, including metabolic cardiology, low-dose medicine, exercise programs, stress management programs, evaluation for inherited risk factors, and various other healing modalities. Metabolic cardiology focuses on the prevention, management, and treatment of cardiovascular disease at the cellular level through biochemical interventions with nutritional supplements that can promote energy production in the heart. Low-dose medicine, on the other hand, interprets pathological phenomena as an imbalance in intercellular signaling that may be corrected through the administration of low physiological doses of messenger molecules. Therapies outside of mainstream medicine may also be deployed in integrative cardiology, for example acupuncture, herbal medicine, and homeopathy. Integrative Cardiology will be of interest to all practitioners wishing to learn about an approach that incorporates the incredible advances in medication and technology with a focus on nutrition, lifestyle, and mind–body influences.
- Contents
- Part I: The Basis of Integration -- 1. Herbal medicine in cardiology -- 2. Homeopathy and cardiovascular disease -- 3. Low-Dose therapy for the treatment of Low Grade Chronic Inflammation -- 4. Acupunture in cardiovascular diseases -- 5. Metabolic cardiology -- 6. Medicinal mushrooms -- 7. Microbiome and cardiac health -- 8. Endocrine system and cardiovascular disease -- 9. Cardiovascular Aging -- 10. Nutrition and cardiac health -- 11. Psycho-neuro-endocrino-immunology paradigm and cardiovascular diseases -- 12. The role of stress and emotions in cardiovascular disease: stress management and meditation programs in the prevention and treatment of cardiovascular disease -- 13. Ozone therapy as a complementary treatment in cardiovascular disease.-- Part II: Integrated Approach to Cardiovascular Disease -- 14. Integrated approach to dyslipidemia -- 15. Integrated approach to hypertension -- 16. Integrated approach to coronary artery disease -- 17. Integrated approach to heart failure -- 18. Integrated approach to arrhythmias -- 19. Integrated approach to oncologic supportive medicine.- 20. Heart and skin : the paradigm of cytokine-mediated cardiovascular metabolic disease in psoriasis.
- Format
- e-Book
- Location
- Online
Management of Adrenal Masses in Children and Adults
https://libcat.nshealth.ca/en/permalink/provcat41513
Electron Kebebew, editor.
--Cham:
Springer
, 2017.
- Available Online
- View e-Book
- Location
- Online
This book is designed to present a comprehensive and state-of the-art approach to the management of adrenal neoplasms that provides a resource to the broad group of providers that will encounter such a patient. Sections address issues that are faced by providers who encounter a patient with an adrenal neoplasm. These areas include an overview of the genetic basis and familial cancer syndrome-associated with adrenal neoplasms, pathobiology, advanced and tumor specific imaging approaches and tech…
- Available Online
- View e-Book
- Other Authors
- Kebebew, Electron
- Responsibility
- Electron Kebebew, editor
- Place of Publication
- Cham
- Publisher
- Springer
- Date of Publication
- 2017
- Physical Description
- 1 online resource (xiv, 310 pages) : 74 illus., 37 illus. in color
- ISBN
- 9783319441368
- 9783319441344 (print ed.)
- Subjects (MeSH)
- Adrenal Gland Diseases - diagnostic imaging
- Adrenal Gland Neoplasms
- Neuroendocrine Tumors
- Abstract
- This book is designed to present a comprehensive and state-of the-art approach to the management of adrenal neoplasms that provides a resource to the broad group of providers that will encounter such a patient. Sections address issues that are faced by providers who encounter a patient with an adrenal neoplasm. These areas include an overview of the genetic basis and familial cancer syndrome-associated with adrenal neoplasms, pathobiology, advanced and tumor specific imaging approaches and technologies, biochemical analysis, standard medical and surgical therapies, and emerging technology and treatment approaches to benign and malignant adrenal neoplasms. Written by experts in the field, each of these sections address level of clinical evidence and provide recommendations and treatment algorithms. Extensive illustrations make this an interactive text. Management of Adrenal Masses in Children and Adults will serve as a very useful resource for all providers dealing with, and interested in this common but challenging tumor. It will provide a concise yet comprehensive summary of the current status of the field that will help guide patient management and stimulate investigative efforts.
- Contents
- 1. Epidemiology of Adrenal Neoplasms -- 2. The Pathology of Adrenal Masses -- 3. Genetics of Benign Adrenocortical Tumors -- 4. Genetics of Adrenocortical Cancers -- 5. Genetics of Pheochromocytoma and Paraganglioma -- 6. Imaging Modalities for Adrenocortical Tumors -- 7. Imaging Modalities for Pheochromocytoma and Paraganglioma -- 8. Primary Hyperaldosteronism -- 9. Cushing Syndrome: Presentation, Diagnosis, and Treatment, Including Subclinical Cushing Syndrome -- 10. Management of Pheochromocytoma and Paraganglioma -- 11. Congenital Adrenal Hyperplasia -- 12. Adrenocortical Carcinoma -- 13. Operative Techniques for Adrenal Neoplasms -- 14. Therapies for Locally Advanced and Metastatic Adrenocortical Carcinoma -- 15. Management of Locally Advanced and Metastatic Pheochromocytoma and Paraganglioma .
- Format
- e-Book
- Location
- Online
