Breastfeeding : a guide for the medical profession
https://libcat.nshealth.ca/en/permalink/provcat30745
edited by Ruth A Lawrence, Robert M Lawrence, Lawrence Noble ... [et al.].
(9th ed.)
--Philadelphia, PA:
Elsevier
, c2022.
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- Online
Written and edited by leading physicians, Breastfeeding: A Guide for the Medical Profession, 9th Edition, offers comprehensive, dependable information and guidance in this multifaceted field. Award-winning author and co-founder of the Academy of Breastfeeding Medicine, Dr. Ruth Lawrence, and her son, Dr. Rob Lawrence, ensure that you’re brought fully up to date on everything from basic data on the anatomical, physiological, biochemical, nutritional, immunological, and psychological aspects of …
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- View e-Book
- Author
- Lawrence, Ruth A.
- Other Authors
- Lawrence, Robert M.
- Responsibility
- edited by Ruth A Lawrence, Robert M Lawrence, Lawrence Noble ... [et al.]
- Edition
- 9th ed.
- Place of Publication
- Philadelphia, PA
- Publisher
- Elsevier
- Date of Publication
- c2022
- Physical Description
- 1 online resource, 1088 p.
- ISBN
- 9780323680134
- Subjects (MeSH)
- Breast Feeding
- Lactation
- Milk, Human
- Specialty
- Nutritional Sciences
- Pediatrics
- Abstract
- Written and edited by leading physicians, Breastfeeding: A Guide for the Medical Profession, 9th Edition, offers comprehensive, dependable information and guidance in this multifaceted field. Award-winning author and co-founder of the Academy of Breastfeeding Medicine, Dr. Ruth Lawrence, and her son, Dr. Rob Lawrence, ensure that you’re brought fully up to date on everything from basic data on the anatomical, physiological, biochemical, nutritional, immunological, and psychological aspects of human lactation, to the problems of clinical management of breastfeeding-all in a highly readable, easily accessible desk reference.
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- Registration required for PDF access.
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- e-Book
- Location
- Online
Sperling pediatric endocrinology
https://libcat.nshealth.ca/en/permalink/provcat32906
editor Mark A. Sperling.
(5th ed.)
--Philadelphia, PA:
Elsevier
, c2021.
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- Online
An ideal resource for both pediatricians and endocrinologists, Sperling’s Pediatric Endocrinology, 5th Edition, brings you fully up to date with accelerating research; new discoveries in metabolic, biochemical and molecular mechanisms; and the resulting advances in today’s clinical care. The editorial team of world-renowned pediatric endocrinologists led by Dr. Mark Sperling, as well as expert contributing authors, cover comprehensive and current aspects of both basic science and clinical prac…
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- View e-Book
- Other Authors
- Sperling, Mark A.
- Responsibility
- editor Mark A. Sperling
- Edition
- 5th ed.
- Alternate Title
- Sperling paediatric endocrinology
- Pediatric endocrinology
- Paediatric endocrinology
- Place of Publication
- Philadelphia, PA
- Publisher
- Elsevier
- Date of Publication
- c2021
- Physical Description
- 1 online resource, 1060 p.
- ISBN
- 9780323625203
- Subjects (MeSH)
- Endocrine System Diseases
- Specialty
- Endocrinology
- Pediatrics
- Abstract
- An ideal resource for both pediatricians and endocrinologists, Sperling’s Pediatric Endocrinology, 5th Edition, brings you fully up to date with accelerating research; new discoveries in metabolic, biochemical and molecular mechanisms; and the resulting advances in today’s clinical care. The editorial team of world-renowned pediatric endocrinologists led by Dr. Mark Sperling, as well as expert contributing authors, cover comprehensive and current aspects of both basic science and clinical practice.
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- Registration required for PDF access.
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- e-Book
- Location
- Online
Influenza : Advances in Diagnosis and Management
https://libcat.nshealth.ca/en/permalink/provcat46416
Jiro Fujita, editor.
--Singapore:
Springer
, c2021.
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- NEW Springer 2021
- Location
- Online
This book explores the latest research and practical data on the clinical management of influenza. Starting with the definition, epidemiology and pathogenesis, the first part reviews the basic science of the influenza virus and infection. The next three parts then discusses the diagnosis, complications and management, providing practical data and insights that are useful in day-to-day patient care. The last part focuses on the trending topics, including a new drug, oral baloxavir marboxil, whic…
- Available Online
- View e-Book
- Other Authors
- Fujita, Jiro
- Responsibility
- Jiro Fujita, editor
- Place of Publication
- Singapore
- Publisher
- Springer
- Date of Publication
- c2021
- Physical Description
- 1 online resource (ix, 229 p.) : 96 illus., 23 illus. in color
- Series
- Respiratory Disease Series: Diagnostic Tools and Disease Managements
- Series Title
- Respiratory disease series
- ISBN
- 9789811591099
- 9789811591082 (Print ed.)
- 9789811591105 (Print ed.)
- 9789811591112 (Print ed.)
- ISSN
- 2509-5552
- Subjects (MeSH)
- Influenza, Human - diagnosis
- Influenza, Human - epidemiology
- Influenza, Human - drug therapy
- Specialty
- Infectious Disease Medicine
- Abstract
- This book explores the latest research and practical data on the clinical management of influenza. Starting with the definition, epidemiology and pathogenesis, the first part reviews the basic science of the influenza virus and infection. The next three parts then discusses the diagnosis, complications and management, providing practical data and insights that are useful in day-to-day patient care. The last part focuses on the trending topics, including a new drug, oral baloxavir marboxil, which was introduced in Japan in 2018 and is the first polymerase inhibitor to be licensed for the treatment of uncomplicated influenza. In Japan, since the medical insurance system is well-established, patients receive medical examinations quickly after the onset of influenza viral infection, making it easy to implement early diagnostic tools and early treatment. Providing practical data and insights, Influenza: Advances in Diagnosis and Management is a useful resource for clinicians, residents and trainees around the globe.
- Contents
- Part I. Introduction -- 1. Global strategy for influenza viral infection: what is the latest Information from WHO? -- Part II. Definition, Epidemiology, and Pathogenesis -- 2. Epidemiology of influenza with a description of recent trends in Japan: what are the key epidemiologic features of seasonal influenza in terms of time, place, person, and virus (overall and in Japan)? -- 3. Transmission of influenza virus in the home: how are they transmitted in the home? -- 4. Cellular and biochemical pathogenic processes in severe influenza virus infection: how does cytokine storm plays a role? -- 5. Pathology of severe influenza virus pneumonia: what is the importance of alveolar mouths? -- 6. Pathology, diagnosis, and treatment of influenza infections/pneumonia: what are the mechanisms of secondary bacterial pneumonia? -- Part III. Diagnosis -- 7. Rapid diagnosis of influenza viral infection: what are the rapid diagnostic tests and molecular diagnosis? -- 8. Differential diagnosis between influenza and other respiratory viral infections: what are the differential diagnoses? -- 9. Radiologic findings of influenza pneumonia: what are the recent radiological findings? -- 10. Oral findings of influenza viral infection: what are the characteristic pharyngeal findings of influenza? -- Part IV. Complication -- 11. Classification of pneumonia complicated with influenza viral infection: what are the patterns of pneumonia? -- 12. Influenza encephalopathy: what is encephalopathy? -- Part V. Management -- 13. Treatment guidelines for influenza virus infection: what does the recent guideline state? -- 14. Treatment strategy for influenza viral infection in adolescent: what is the current adolescent treatment? -- 15. How to use anti-influenza drugs: zanamivir and oseltamivir -- 16. How to use anti-influenza drugs: laninamivir octanoate -- 17. How to use anti-influenza drugs: baloxavir marboxil -- 18. How to use anti-influenza drugs: peramivir -- 19. Prophylaxis of influenza viral transmission: what is the current prophylaxis? -- Part VI. Topics -- 20. Influenza vaccine efficacy/effectiveness: with special reference to current epidemiological methodology -- 21. The new anti-influenza drug baloxavir marboxil: can influenza viruses with reduced susceptibility to baloxavir maintain viral fitness? -- 22. Viruses resistant to oseltamivir or baloxavir: what do the data reveal about resistance?
- Access
- NEW Springer 2021
- Format
- e-Book
- Location
- Online
Locoregional Radionuclide Cancer Therapy : Clinical and Scientific Aspects
https://libcat.nshealth.ca/en/permalink/provcat46497
Franklin C.L. Wong, editor.
--Cham:
Springer
, c2021.
- Available Online
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- NEW Springer 2021
- Location
- Online
This book reviews locoregional radionuclide cancer therapies (LRCT). Proving an increasingly viable alternative to radiotherapy, radionuclide therapy includes a diversity of choices of well characterized biochemical and physiologic target molecules. The delivery and retention of radionuclides may be monitored by advanced imaging for exact tissue localization and for real-time dosimetry to enable personalized precision medicine. Radiopharmaceuticals in human cancer therapies are typically delive…
- Available Online
- View e-Book
- Other Authors
- Wong, Franklin C.L.
- Responsibility
- Franklin C.L. Wong, editor
- Place of Publication
- Cham
- Publisher
- Springer
- Date of Publication
- c2021
- Physical Description
- 1 online resource (xii, 268 p.) : 76 illus., 56 illus. in color
- ISBN
- 9783030562670
- 9783030562663 (Print ed.)
- 9783030562687 (Print ed.)
- 9783030562694 (Print ed.)
- Subjects (MeSH)
- Neoplasms - radiotherapy
- Radiopharmaceuticals - therapeutic use
- Radiotherapy Dosage
- Radiotherapy - methods
- Specialty
- Medical Oncology
- Radiotherapy
- Abstract
- This book reviews locoregional radionuclide cancer therapies (LRCT). Proving an increasingly viable alternative to radiotherapy, radionuclide therapy includes a diversity of choices of well characterized biochemical and physiologic target molecules. The delivery and retention of radionuclides may be monitored by advanced imaging for exact tissue localization and for real-time dosimetry to enable personalized precision medicine. Radiopharmaceuticals in human cancer therapies are typically delivered in systemic routes but can also be designed for locoregional routes to harness pharmacokinetic advantages of higher payload and lower systemic toxicities. This book explores the latest advancements and clinical considerations of the locoregional approach. Throughout the chapters, the clinical and scientific bases of cancer treatment and the locoregional use of radionculides are explored. Mathematical models of radiation dosimetry of locoregional radionculdies on tissues are studied using common models for multiple commercially available radionuclides. Rodent and canine tumor models of LRCT are compared for selected radionuclides and radiopharmaceuticals. The practical aspects of radiopharmaceuticals production, marketing, transport, as well as radiation protection are reviewed. Finally, the combination of LRCT with immunotherapy and other cancer therapies and prospective future use of LRCT are discussed. This is a guide for practicing nuclear physicians, interventional radiologists, radiation oncologists, radiation scientists, veterinarians and oncologists to expand their knowledge base and to prepare for designing locoregional radionuclide cancer therapies in animals and in humans.
- Contents
- 1. Human Cancer: Epidemiology, Hallmarks, and Defense Strategies -- 2. Cancer Treatment Modalities Systemic and Locoregional Approaches: Challenges and Opportunities of Multidisciplinary Approaches -- 3. Cancer Radiotherapy: General Considerations and Human Radiobiology -- 4. Radionuclide Cancer Therapy: Unsealed Alpha- and Beta-Emitters - 5. Locoregional Therapy: Cancer Interventions with and Without Radionuclides -- 6. Radiation Dosimetry Considerations of Locoregional Radionuclide Cancer Therapy -- 7. Voxel-Based Targeted Radionuclide Therapy Dosimetry -- 8. Locoregional Unsealed Radionuclide Cancer Therapy: Experimental Findings -- 9. Animal Cancer Therapy Models: Ready Translation to Humans -- 10. An Overview of the Regulations of Radiopharmaceuticals -- 11. Locoregional Radionuclide Cancer Therapy (LRCT) Using Sealed and Unsealed Radionuclides.
- Access
- NEW Springer 2021
- Format
- e-Book
- Location
- Online
Preterm Labor and Delivery
https://libcat.nshealth.ca/en/permalink/provcat44854
Hiroshi Sameshima, editor.
--Singapore:
Springer
, c2020.
- Available Online
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- Location
- Online
This splendid volume presents numerous aspects of preterm labor and delivery, from its fundamental mechanism to clinically focused approaches. The incidence of preterm delivery is 6-7% in Japan, while globally up to 10% of pregnancies with preterm labor result in premature delivery. The rates of overall survival and intact survival of the premature infants are also excellent in Japan. Thus Japan’s approach to preterm labor and delivery has long attracted attention. In each chapter, experts desc…
- Available Online
- View e-Book
- Other Authors
- Sameshima, Hiroshi
- Responsibility
- Hiroshi Sameshima, editor
- Place of Publication
- Singapore
- Publisher
- Springer
- Date of Publication
- c2020
- Physical Description
- 1 online resource (viii, 252 p.) : 47 illus., 33 illus. in color
- Series Title
- Comprehensive gynecology and obstetrics
- ISBN
- 9789811398759
- 9789811398742 (Print ed.)
- 9789811398766 (Print ed.)
- 9789811398773 (Print ed.)
- ISSN
- 2364-1932
- Subjects (MeSH)
- Delivery, Obstetric
- Infant, Premature
- Obstetric Labor, Premature
- Specialty
- Obstetrics
- Perinatology
- Abstract
- This splendid volume presents numerous aspects of preterm labor and delivery, from its fundamental mechanism to clinically focused approaches. The incidence of preterm delivery is 6-7% in Japan, while globally up to 10% of pregnancies with preterm labor result in premature delivery. The rates of overall survival and intact survival of the premature infants are also excellent in Japan. Thus Japan’s approach to preterm labor and delivery has long attracted attention. In each chapter, experts describe specific issues unique to conditions in Japan, including diagnosis, tocolytic agents, definition of clinical chorioamnionitis, treatment of bacterial vaginosis, role of amniocentesis, management of preterm premature membrane rupture and also placental pathology, presenting definitive evidence of the reduced incidence of preterm delivery in Japan. This book benefits not only obstetricians, pediatricians and gynecologist, but also midwives, nurse practitioners, and medical and associated staffs in the field of obstetrics, pediatrics, as well as neonatal and perinatal medicine who are involved in delivery.
- Contents
- Part I. Preterm labor: A challenge -- 1. Preterm labor: impacts on perinatal ecology -- 2. Definition and diagnosis of preterm labor -- 3. Epidemiology and incidence of preterm delivery -- Part II. Preterm labor and intrauterine infection and inflammation -- 4. Subclinical intrauterine infection -- 5. Clinical and subclinical intrauterine infection/inflammation -- 6. Cervical changes 1: morphological and biochemical changes -- 7. Cervical changes 2 : USG findings -- Part III. Other mechanisms related to preterm labor -- 8. Multiple mechanisms of preterm labor other than intrauterine infection -- 9. Abruption and preterm labor -- Part IV. Prevention, Treatment, and Management -- 10. Prevention and Tocolytic agents 1 -- 11. Prevention and Tocolytic agents 2 -- 12. Tocolytic agent 3 -- 13. Antibiotics for preterm labor -- 14. Probiotics for preterm labor -- 15. Progesterone -- 16. Cerclage 1: general -- 17. Cerclage 2: abdominal vs vaginal -- 18. Bacterial vaginosis -- 19. Antenatal corticosteroid -- 20. Mode of delivery of premature infants -- 21. Management of pPROM in general -- 22. Prevention of PTB: meta-analysis -- Part V. Preterm Newborn -- 23. The preterm newborn: Morbidity and Mortality -- Part VI. Placental Pathology 24. Placental pathology -- Part VII. Research Frontier -- 25. Genetic analysis of spontaneous preterm birth.
- Format
- e-Book
- Location
- Online
Osteoporosis : Pathophysiology and Clinical Management
https://libcat.nshealth.ca/en/permalink/provcat44861
Benjamin Z. Leder, Marc N. Wein, editors.
(Third edition)
--Cham:
Humana Press
, c2020.
- Available Online
- View e-Book
- Location
- Online
Completely revised and updated, and utilizing the most current evidence and practice guidelines for the treatment of osteoporosis, this comprehensive third edition discusses the basic aspects of bone metabolism, the pathophysiology of osteoporosis, current diagnostic techniques and medical treatment strategies. Osteoporosis is a common disorder that is prevalent in over 20 million Americans over the age of 60. One and a half million osteoporotic fractures occur in the United States every year, …
- Available Online
- View e-Book
- Other Authors
- Leder, Benjamin Z.
- Wein, Marc N.
- Responsibility
- Benjamin Z. Leder, Marc N. Wein, editors
- Edition
- Third edition
- Place of Publication
- Cham
- Publisher
- Humana Press
- Date of Publication
- c2020
- Physical Description
- 1 online resource (xv, 516 p.) : 82 illus., 46 illus. in color
- Series
- Contemporary Endocrinology
- Series Title
- Contemporary endocrinology
- ISBN
- 9783319692876
- 9783319692869 (Print ed.)
- 9783319692883 (Print ed.)
- ISSN
- 2523-3785
- Subjects (MeSH)
- Osteoporosis - physiopathology
- Osteoporosis - therapy
- Specialty
- Osteology
- Abstract
- Completely revised and updated, and utilizing the most current evidence and practice guidelines for the treatment of osteoporosis, this comprehensive third edition discusses the basic aspects of bone metabolism, the pathophysiology of osteoporosis, current diagnostic techniques and medical treatment strategies. Osteoporosis is a common disorder that is prevalent in over 20 million Americans over the age of 60. One and a half million osteoporotic fractures occur in the United States every year, including 300,000 hip fractures. Mortality rates after hip fracture approach 25%, with another 50% of patients experiencing a major decrease in their prior level of independence and quality of life. Despite the wide prevalence and severe consequences of osteoporosis, it remains a disorder that is severely under-diagnosed and treated. In this context, specialists and primary care physicians alike are having increasing difficulty keeping up with the rapid changes to the field and incorporating these advances to clinical care. In the years since the last edition of this book was published, the osteoporosis field has changed drastically. In addition to revising and updating existing chapters and removing a few that are no longer as relevant, new chapters discuss an advanced understanding of the cellular and molecular mechanisms underlying the disorder, the introduction of new diagnostic imaging techniques, a more nuanced appreciation of the risks and benefits of osteoporosis therapies, and the introduction of two new classes of osteoporosis medications. Following the format of the second edition, and including helpful key points at the opening of each chapter, this text will present a comprehensive overview of both the basic and clinical concepts relating to each topic, when appropriate. Chapter authors were chosen based on their high level of expertise and leadership in the field. Taken together, this text should thus be of great interest to physicians of multiple specialties, allied health professionals, as well as basic and clinical researchers.
- Contents
- Basic Aspects of Osteoblast Function -- Basic Aspects of Osteoclast Differentiation and Function -- Basic Aspects of Osteocyte Function -- Vitamin D and Bone Health: Basic and Clinical Aspects -- Basic Aspects of Bone Mineralization -- Determinants of Peak Bone Mass Acquisition -- Osteoporosis Screening and Diagnosis -- New Imaging Techniques for Bone -- Biochemical Markers of Bone Turnover -- Biomechanics of Bone -- Exercise in the Prevention of Osteoporosis-Related Fractures -- Effects of Estrogens and SERMs on Bone Metabolism: Clinical Aspects -- The Effects of Androgens on Bone Metabolism: Clinical Aspects -- Bisphosphonates: Mechanisms of Action and Role in Osteoporosis Therapy -- Denosumab: Mechanisms and Therapeutic Effects in the Treatment of Osteoporosis -- The Parathyroid Hormone Receptor Type 1 -- PTH and PTHrP Analogs: Treatment of Osteoporosis -- Combination and Sequential Osteoanabolic/Antiresorptive Therapy in Osteoporosis Treatment -- Sclerostin Inhibition in the Treatment of Osteoporosis -- Osteoporosis in Men. Glucocorticoid-Induced Osteoporosis -- Transplantation Osteoporosis -- Osteoporosis in Premenopausal Women -- Safety Considerations for Osteoporosis Therapies -- Genetic Determinants and Pharmacogenetics of Osteoporosis and Osteoporotic Fracture.
- Format
- e-Book
- Location
- Online
Biochemistry for Anesthesiologists and Intensivists
https://libcat.nshealth.ca/en/permalink/provcat45100
Fernando Alemanno, editor.
--Cham:
Springer
, c2020.
- Available Online
- View e-Book
- Location
- Online
This book discusses and explains the importance of biochemistry knowledge in understanding what happens to patients during anesthesia and/or to those being in intensive care. Anesthesiological and intensive care practice require a detailed biochemistry knowledge to avoid onset of complications and/or to deal with unexpected events promptly and appropriately. The book is intended for anesthesiologists, intensivists, anesthesia teachers, anesthesia trainees and residents.
- Available Online
- View e-Book
- Other Authors
- Alemanno, Fernando
- Responsibility
- Fernando Alemanno, editor
- Place of Publication
- Cham
- Publisher
- Springer
- Date of Publication
- c2020
- Physical Description
- 1 online resource (xiv, 250 p.) : 65 illus., 22 illus. in color
- ISBN
- 9783030267216
- 9783030267209 (Print ed.)
- 9783030267223 (Print ed.)
- 9783030267230 (Print ed.)
- Subjects (MeSH)
- Anesthesia
- Anesthetics - adverse effects
- Anesthetics - pharmacology
- Biochemical Phenomena
- Critical Care
- Specialty
- Anesthesiology
- Biochemistry
- Abstract
- This book discusses and explains the importance of biochemistry knowledge in understanding what happens to patients during anesthesia and/or to those being in intensive care. Anesthesiological and intensive care practice require a detailed biochemistry knowledge to avoid onset of complications and/or to deal with unexpected events promptly and appropriately. The book is intended for anesthesiologists, intensivists, anesthesia teachers, anesthesia trainees and residents.
- Contents
- 1. Enzymes and Coenzymes (A Brief, Boring but Necessary Preamble) -- 2. Anaerobic Glycolysis or Embden–Meyerhof Pathway -- 3. Tricarboxylic Acids Cycle or Krebs Cycle -- 4. Glutamate – GABA Collateral Cycle -- 5. Hexose-Monophosphate Shunt or Horecker Cycle (The Sleep Pathway) -- 6. Neurotransmitters -- 7. The Blood-Brain Barrier (BBB) -- 8. Shock -- 9. Cerebral Edema -- 10. The Pulmonary Surfactant -- 11. When the Mind Does Not Work As It Should -- 12. Thiamine (Vitamin B1) -- 13. Normobaric Oxygen Therapy (NBO) -- 14. Acid-Base Equilibrium -- 15. Theories of Narcosis -- 16. Local Anaesthetics -- 17. Perineural Adjuvants -- 18. The Grand Design -- 19. Epilogue and Farewell.
- Format
- e-Book
- Location
- Online
Insulin Resistance : Childhood Precursors of Adult Disease
https://libcat.nshealth.ca/en/permalink/provcat45108
Philip S. Zeitler, Kristen J. Nadeau, editors.
(Second edition)
--Cham:
Humana Press
, c2020.
- Available Online
- View e-Book
- Location
- Online
Now in a revised and expanded second edition, this unique text presents topics related to insulin resistance in youth and its consequences across the lifespan. In the first section of the book examining epidemiology, the contributors review controversies over the definition of insulin resistance in children and what is known about how insulin resistance in youth differs from adults, the measurement of insulin resistance in youth in the research and clinical settings, and current knowledge regar…
- Available Online
- View e-Book
- Other Authors
- Zeitler, Philip S.
- Nadeau, Kristen J.
- Responsibility
- Philip S. Zeitler, Kristen J. Nadeau, editors
- Edition
- Second edition
- Place of Publication
- Cham
- Publisher
- Humana Press
- Date of Publication
- c2020
- Physical Description
- 1 online resource (xvi, 356 p.) : 41 illus., 19 illus. in color
- Series Title
- Contemporary endocrinology
- ISBN
- 9783030250577
- 9783030250553 (Print ed.)
- 9783030250560 (Print ed.)
- ISSN
- 2523-3785
- Subjects (MeSH)
- Insulin Resistance
- Specialty
- Endocrinology
- Abstract
- Now in a revised and expanded second edition, this unique text presents topics related to insulin resistance in youth and its consequences across the lifespan. In the first section of the book examining epidemiology, the contributors review controversies over the definition of insulin resistance in children and what is known about how insulin resistance in youth differs from adults, the measurement of insulin resistance in youth in the research and clinical settings, and current knowledge regarding the epidemiology of insulin resistance in the pediatric population. The second section of the book explores pathophysiology, including current knowledge of the molecular, metabolic, and physiologic mechanisms of insulin resistance, the unique pathophysiology of pregnancy and puberty, the contributions of the prenatal and early childhood environment to the development of insulin resistance, and adipose and biochemical mediators. This section concludes with discussion of the relationship between insulin resistance and cardiovascular disease and liver disorders. A third section, new to this second edition, explores insulin resistance in unique models: intrauterine growth restriction and girls with polycystic ovary syndrome and metabolic syndrome. The final section of the book explores the concepts of treatment through medications directed at insulin sensitivity, as well as exercise, weight loss medications and consequences of bariatric surgery. Insulin Resistance: Childhood Precursors of Adult Disease, Second Edition provides up-to-date reviews of all of these areas, providing the reader with a current perspective on issues in insulin resistance in youth, an emerging risk factor for disease across the lifespan, that will spur continued interest in the topic on the part of clinicians and researchers, perhaps promoting new points of view and creative approaches to this daunting challenge.
- Contents
- Part I: Definition and Epidemiology -- Clinical Manifestations of Insulin Resistance in Youth -- Techniques to Assess Insulin Action in Youth -- Insulin Resistance in Chronic Disease -- Part II: Pathophysiology -- Molecular Mechanisms of Insulin Resistance -- Insulin Resistance in Pregnancy: Implications for Mother and Offspring -- Maternal-Fetal Contributors to Insulin Resistance Syndrome in Youth -- Early Childhood Contributions to Insulin Resistance -- Insulin Resistance in Puberty -- Adiposity Is the Enemy: Body Composition and Insulin Sensitivity -- Ectopic Fat and Insulin Resistance in Youth -- Biomarkers of Insulin Resistance -- Insulin Resistance and Cardiovascular Disease -- The Liver and Insulin Resistance: The Important Convergence of Endocrinology and Hepatology -- Insulin Resistance and the Kidney in Youth -- Part III: Unique Models of Insulin Resistance in Youth -- Intrauterine Growth Restriction and Insulin Resistance -- Polycystic Ovary Syndrome and Metabolic Syndrome -- Part IV: Treatment -- Is Insulin Resistance a Treatment Target?- Exercise in Metabolic Syndrome and Diabetes: A Central Role for Insulin Sensitivity -- Weight Loss Medications in Adolescents -- Adolescent Metabolic/Bariatric Surgery: Effects on Obesity, Comorbidities, and Insulin Resistance.
- Format
- e-Book
- Location
- Online
Practical Aspects of Cosmetic Testing : How to Set up a Scientific Study in Skin Physiology
https://libcat.nshealth.ca/en/permalink/provcat45221
Joachim W. Fluhr, editor.
(Second edition)
--Cham:
Springer
, c2020.
- Available Online
- View e-Book
- Location
- Online
Skin physiology assessment is moving from a descriptive approach to a deeper understanding of biophysical and biochemical processes in the stratum corneum, such as epidermal barrier function and stratum corneum hydration. New, non-invasive approaches offer reliable and reproducible methods for product testing in the pharmaceutical and cosmetic industry, as well as in basic research. While standard instruments focus on functional aspects, innovative devices offer a deeper understanding of underl…
- Available Online
- View e-Book
- Other Authors
- Fluhr, Joachim W.
- Responsibility
- Joachim W. Fluhr, editor
- Edition
- Second edition
- Place of Publication
- Cham
- Publisher
- Springer
- Date of Publication
- c2020
- Physical Description
- 1 online resource (x, 317 p.) : 34 illus., 24 illus. in color
- ISBN
- 9783030449674
- 9783030449667 (Print ed.)
- 9783030449681 (Print ed.)
- 9783030449698 (Print ed.)
- Subjects (MeSH)
- Cosmetics
- Skin Physiological Phenomena
- Skin Tests
- Specialty
- Dermatology
- Physiology
- Abstract
- Skin physiology assessment is moving from a descriptive approach to a deeper understanding of biophysical and biochemical processes in the stratum corneum, such as epidermal barrier function and stratum corneum hydration. New, non-invasive approaches offer reliable and reproducible methods for product testing in the pharmaceutical and cosmetic industry, as well as in basic research. While standard instruments focus on functional aspects, innovative devices offer a deeper understanding of underlying mechanisms. This book discusses the assessment of skin physiology and of skin functions in clinical studies using non-invasive biophysical instruments, offering readers a comprehensive guide to planning, performing and evaluating the results of scientific studies in skin measurement and the legal framework for these studies. Written by leading experts in the field, it focuses on practical aspects of non-invasive measurements. After introducing the legal aspects of the current framework for clinical cosmetic studies and basic research in cosmetology, it explores the technical practicalities of organizing a testing lab and the pre-requirements for planning a study. The third and main section addresses specific topics in cosmetic testing e.g. skin hydration, and also includes chapters on sensory aspects and in vivo skin structure vizualization. This new, updated edition of Practical Aspects of Cosmetic Testing is a valuable tool for researchers, students, and medical staff wanting to gain insights into how best to assess skin functions in controlled studies using non-invasive biophysical instruments.
- Contents
- 1. Regulatory Aspects -- 2. Ethical aspects of cosmetic testing -- 3. Good Clinical Practice -- 4. Guidelines in Skin Testing -- 5. Claim Support: How to Create and Substantiate Claims -- 6. Testing Laboratory -- 7. Research Staff -- 8. Testing Population -- 9. Testing Devices and Methods -- 10. Factors Influencing Measurements -- 11. Study Design -- 12. Cosmetic Testing Report -- 13. Moisturizers and Emollients -- 14. Antiaging and Antiwrinkle Products -- 15. Products for Impure Skin and Acne-like Skin -- 16. Assessment of Hair Morphology -- 17. Skin Colour and Pigmentation -- 18. Characterization of Sunscreens: Determination of the SPF -- 19. Practical Aspects of Shampoo and Conditioner Testing -- 20. Antiperspirants and Deodorants -- 21. Hair Growth -- 22. Sensory Perception -- 23. Novel Methods for In Vivo Skin Structure Visualization -- 24. Assessment of Pruritus and Sensitive Skin -- 25. Practical Use and Significance of Transepidermal Water Loss Measurements -- 26. Compliance Check with On-Site Measurements: Advanced Ways in Product Testing.
- Format
- e-Book
- Location
- Online
Nutrition in Kidney Disease
https://libcat.nshealth.ca/en/permalink/provcat45223
Jerrilynn D. Burrowes, Csaba P. Kovesdy, Laura D. Byham-Gray, editors.
(Third edition)
--Cham:
Humana Press
, c2020.
- Available Online
- View e-Book
- Location
- Online
This third edition of this text is organized into seven sections that address the educational needs of dietitians and other health care professionals around the world who seek current information about nutritional management of chronic kidney disease (CKD). Part I addresses the differences in the epidemiology of CKD and renal replacement therapy worldwide, such as environmental, ethnic, cultural, political and macroeconomic factors. Part II includes a thorough review of the components of the nu…
- Available Online
- View e-Book
- Other Authors
- Burrowes, Jerrilynn D.
- Kovesdy, Csaba P.
- Byham-Gray, Laura D.
- Responsibility
- Jerrilynn D. Burrowes, Csaba P. Kovesdy, Laura D. Byham-Gray, editors
- Edition
- Third edition
- Place of Publication
- Cham
- Publisher
- Humana Press
- Date of Publication
- c2020
- Physical Description
- 1 online resource (xliv, 694 p.) : 30 illus. in color
- Series
- Nutrition and Health
- Series Title
- Nutrition and health (Totowa, N.J.)
- ISBN
- 9783030448585
- 9783030448578 (Print ed.)
- 9783030448592 (Print ed.)
- 9783030448608 (Print ed.)
- Subjects (MeSH)
- Chronic Disease - prevention & control
- Kidney Diseases - diet therapy
- Nutritional Physiological Phenomena
- Specialty
- Nephrology
- Nutrition Therapy
- Abstract
- This third edition of this text is organized into seven sections that address the educational needs of dietitians and other health care professionals around the world who seek current information about nutritional management of chronic kidney disease (CKD). Part I addresses the differences in the epidemiology of CKD and renal replacement therapy worldwide, such as environmental, ethnic, cultural, political and macroeconomic factors. Part II includes a thorough review of the components of the nutrition assessment, which includes information about psychosocial issues affecting nutritional status in kidney disease and drug-nutrient interactions, and parts III and IV review preventative strategies for common disorders associated with CKD such as hypertension, type 2 diabetes, obesity and cardiovascular disease, and current evidence-based treatment recommendations for the nutrition management of non-dialyzed, dialyzed and transplanted adults are addressed. Part V presents the nutritional concerns of CKD populations with special needs (i.e., pregnancy, infancy, childhood, adolescence and the elderly). The nutrition management of other disorders associated with kidney disease are covered in Part VI; these include protein-energy wasting and the inflammatory response, bone and mineral disorders, nephrotic syndrome, nephrolithiasis, and acute kidney injury. Lastly, Part VII is devoted to cutting-edge research on topics of concern in nutrition in kidney disease such as the gut microbiome including pre- and probiotics, appetite regulation, advanced glycation end products, physical activity and structured exercise, and dietary patterns including plant-based diets. When appropriate, the new clinical practice guidelines in nutrition for individuals with CKD are integrated into the chapters. The third edition of Nutrition in Kidney Disease will be a highly informative resource for nephrologists, nutrition scientists, nutritionists, and researchers and students whose research, practice, and education includes nutrition and kidney disease.
- Contents
- Part I. Foundations for Clinical Practice and Overview -- Epidemiology and Changing Demographics of Chronic Kidney Disease in the United States and Abroad -- History of Dietary Protein Treatment for Non-dialyzed Chronic Kidney Disease Patients -- Kidney Function in Health and Disease -- Part II. Components of the Nutrition Assessment -- Anthropometric Assessment in Kidney Disease -- Biochemical Nutritional Assessment in Chronic Kidney Disease -- Nutrition-focused Physical Examination and Assessment in Chronic Kidney Disease -- Dietary Assessment in Kidney Disease -- Psychosocial Issues Affecting Nutrtional Status in Kidney Disease -- Drug-Nutrient Interactions -- Part III. Preventative Strategies for Chronic Kidney Disease Among Adults -- Hypertension -- Diabetes Mellitus and Chronic Kidney Disease (stages 1-5) -- Implications and Management of Obesity in Kidney Disease -- Nutritional Management of Cardiovascular Disease -- Part IV. Chronic Kidney Disease in Adults Treated by Renal Replacement Therapies -- CKD Stages 1-5 (Non-dialysis) -- Maintenance Hemodialysis -- Peritonal Dialysis -- Nutrition Support in Hemodialysis and Peritoneal Dialysis -- Kidney Transplantation -- Part V. Nutrition in Chronic Kidney Disease Among Special Needs Populations -- Pregnancy -- Infancy, Childhood, and Adolescence -- The Aging Adult and Chronic Kidney Disease -- Part VI. Nutritional Management of Other Disorders that Impact Kidney Function -- Protein-Energy Wasting/Malnutrition and the Inflammatory Response -- Bone and Mineral Disorders -- Nephrotic Syndrome -- Nephrolithiasis -- Acute Kidney Injury -- Part VII. Additional Nutritional Considerations in Kidney Disease -- The Gut Microbiome -- Appetite Regulation -- Advanced Glycation End Products -- Physical Activity and Exercise in Chronic Kidney Disease -- Dietary Patterns -- Herbal and Other Natural Dietary Supplements -- Vitamin and Trace Element Needs in Chronic Kidney Disease -- Factors Affecting Dietary Adherence and Strategies for Improving Adherence in Chronic Kidney Disease -- Effective Communication and Counseling Approaches -- Comparative Effectiveness Research and Renal Nutrition -- Suggested Resources for the Practitioner.
- Format
- e-Book
- Location
- Online
Parathyroid Glands in Chronic Kidney Disease
https://libcat.nshealth.ca/en/permalink/provcat45256
Adrian Covic, David Goldsmith, Pablo A. Ureña Torres, editors.
--Cham:
Springer
, c2020.
- Available Online
- View e-Book
- Location
- Online
This concise book provides practical strategies to help nephrologists and endocrinologists correctly diagnose and treat the various forms of parathyroid disease they may encounter in the management of chronic kidney disease. Each chapter deals with various topics related to parathyroid gland anatomy and physiology, as well as diagnostic tests and their particularities in regard to chronic disease. The book highlights the range of therapies used for the treatment of secondary hyperparathyroidism…
- Available Online
- View e-Book
- Other Authors
- Covic, Adrian
- Goldsmith, David
- Ureña Torres, Pablo A.
- Responsibility
- Adrian Covic, David Goldsmith, Pablo A. Ureña Torres, editors
- Place of Publication
- Cham
- Publisher
- Springer
- Date of Publication
- c2020
- Physical Description
- 1 online resource (vi, 196 p.) : 21 illus., 18 illus. in color
- ISBN
- 9783030437695
- 9783030437688 (Print ed.)
- 9783030437701 (Print ed.)
- 9783030437718 (Print ed.)
- Subjects (MeSH)
- Parathyroid Glands - physiopathology
- Renal Insufficiency, Chronic - complications
- Renal Insufficiency, Chronic - physiopathology
- Specialty
- Endocrinology
- Nephrology
- Abstract
- This concise book provides practical strategies to help nephrologists and endocrinologists correctly diagnose and treat the various forms of parathyroid disease they may encounter in the management of chronic kidney disease. Each chapter deals with various topics related to parathyroid gland anatomy and physiology, as well as diagnostic tests and their particularities in regard to chronic disease. The book highlights the range of therapies used for the treatment of secondary hyperparathyroidism, and critically analyses the latest research in the field. Providing an up-to-date review of the current literature, including innovations in both medical and surgical treatment and current indications for parathyroidectomy, this practice-oriented book is an excellent resource for nephrologists, endocrinologists, endocrine surgeons and family medicine physicians.
- Contents
- Parathyroid Glands in CKD: Anatomy, Histology, Physiology and Molecular Biology in CKD -- PTH Regulation by the Klotho/FGF23 Axis in CKD -- Parathyroid Imaging in Patients with Renal Hyperparathyroidism -- PTH Receptors and Skeletal Resistance to PTH Action -- PTH Regulation by Phosphate and miRNAs -- PTH Measurement in CKD -- Relation Between PTH and Biochemical Markers of MBD -- Effect of PTH on the Hematologic System -- Parathyroid Hormone as a Uremic Toxin -- Control of Secondary Hyperparathyroidism (SPHT) by Older and Newer Vitamin D Compounds -- The Role of the Old and the New Calcimimetic Agents in Chronic Kidney Disease-Mineral and Bone Disorder -- Parathyroidectomy in Chronic Kidney Disease -- Relation Between PTH and the Risk of Mortality in CKD.
- Format
- e-Book
- Location
- Online
Breath Odors : Origin, Diagnosis, and Management
https://libcat.nshealth.ca/en/permalink/provcat45350
Nir Sterer, Mel Rosenberg.
(Second edition)
--Cham:
Springer
, c2020.
- Available Online
- View e-Book
- Location
- Online
This comprehensive, evidence-based textbook presents the latest knowledge on bad breath, describing insights from basic research and offering expert guidance on current approaches to diagnosis and treatment. The new edition has been thoroughly updated to take account of recent advances in understanding. The opening chapters examine in detail the origins of bad breath, including from the nose and pharynx. Microbial and biochemical aspects are fully explained, and information is also provided on …
- Available Online
- View e-Book
- Author
- Sterer, Nir
- Other Authors
- Rosenberg, Mel
- Responsibility
- Nir Sterer, Mel Rosenberg
- Edition
- Second edition
- Alternate Title
- Breath odours
- Place of Publication
- Cham
- Publisher
- Springer
- Date of Publication
- c2020
- Physical Description
- 1 online resource (vii, 104 p.) : 13 illus., 12 illus. in color
- ISBN
- 9783030447311
- 9783030447304 (Print ed.)
- 9783030447328 (Print ed.)
- 9783030447335 (Print ed.)
- Subjects (MeSH)
- Halitosis - diagnosis
- Halitosis - etiology
- Halitosis - therapy
- Subjects (LCSH)
- Dentistry
- Abstract
- This comprehensive, evidence-based textbook presents the latest knowledge on bad breath, describing insights from basic research and offering expert guidance on current approaches to diagnosis and treatment. The new edition has been thoroughly updated to take account of recent advances in understanding. The opening chapters examine in detail the origins of bad breath, including from the nose and pharynx. Microbial and biochemical aspects are fully explained, and information is also provided on odor perception. The clinically focused chapters cover all forms of laboratory measurement of breath odors, chairside diagnostic techniques, and the full range of available treatment options. The value of self-administered questionnaires in assessing bad breath is discussed, and attention is paid to the problem in specific population groups and to psychological aspects. Finally, future prospects are reviewed. The authors draw on more than forty years of combined experience in the field, both in the laboratory and as consultants to thousands of patients. The book will be of interest to all dentists as well as ENT specialists and family physicians.
- Contents
- 1. Introduction -- 2. Breath Odors of Oral Origin (Oral Malodor) -- 3. Biochemical and Microbial Aspects of Oral Malodor Production -- 4. Odor Perception -- 5. Breath Odors of Nasal and Pharyngeal Origin -- 6. Breath Odors and the Gastrointestinal Tract -- 7. Other Sources of Breath Odors -- 8. Measurements of Breath Odors and Related Parameters -- 9. Breath Odor Diagnosis -- 10. Self-Assessment of Breath Odors -- 11. Breath Odors, Prevalence, Gender, and Age -- 12. Psychological Aspects of Breath Odors -- 13. Oral Malodor Management -- 14. History of Breath Odors -- 15. Future Prospects.
- Format
- e-Book
- Location
- Online
Diagnosis and Management of Autoimmune Hepatitis : A Clinical Guide
https://libcat.nshealth.ca/en/permalink/provcat45356
Mark W. Russo, editor.
--Cham:
Springer
, c2020.
- Available Online
- View e-Book
- Location
- Online
This text provides a concise yet comprehensive overview of autoimmune hepatitis (AIH). The book reviews diagnosis criteria for AIH, biochemical and histologic findings in typical and atypical cases, and treatment with first, second, and third line therapies. Furthermore, the book discusses management of AIH for specific patient populations, including pediatric patients, pregnant patients, and patients undergoing liver transplantation. Criteria for stopping therapy and risk of relapse, studies d…
- Available Online
- View e-Book
- Other Authors
- Russo, Mark W.
- Responsibility
- Mark W. Russo, editor
- Place of Publication
- Cham
- Publisher
- Springer
- Date of Publication
- c2020
- Physical Description
- 1 online resource (x, 166 p.) : 35 illus., 33 illus. in color
- ISBN
- 9783030336288
- 9783030336271 (Print ed.)
- 9783030336295 (Print ed.)
- 9783030336301 (Print ed.)
- Subjects (MeSH)
- Hepatitis, Autoimmune
- Specialty
- Allergy and Immunology
- Gastroenterology
- Virology
- Abstract
- This text provides a concise yet comprehensive overview of autoimmune hepatitis (AIH). The book reviews diagnosis criteria for AIH, biochemical and histologic findings in typical and atypical cases, and treatment with first, second, and third line therapies. Furthermore, the book discusses management of AIH for specific patient populations, including pediatric patients, pregnant patients, and patients undergoing liver transplantation. Criteria for stopping therapy and risk of relapse, studies demonstrating the efficacy and safety of alternatives to corticosteroids, and diagnosis and treatment of overlap syndromes are also explored in the text. Written by experts in the field, Diagnosis and Treatment of Autoimmune Hepatitis: A Clinical Guide is a state-of-the-art resource for clinicians and practitioners who treat and manage patients with AIH.
- Contents
- Epidemiology and Burden of Disease -- The Pathogenesis of Autoimmune Liver Diseases -- Clinical Presentation and Diagnosis -- The Pathology of Autoimmune Hepatitis -- Treating the Adult Patient-First Line Therapy -- Treating the Adult Patient: Alternative Drug Therapies -- The Approach to the Pediatric Patient -- Autoimmune Hepatitis and Pregnancy -- Liver Transplantation for Autoimmune Hepatitis -- Autoimmune Overlap Syndromes -- Drug Induced Liver Injury with Autoimmune Features.
- Format
- e-Book
- Location
- Online
Integrative and Functional Medical Nutrition Therapy : Principles and Practices
https://libcat.nshealth.ca/en/permalink/provcat45399
Diana Noland, Jeanne A. Drisko, Leigh Wagner, editors.
--Cham:
Humana Press
, c2020.
- Available Online
- View e-Book
- Location
- Online
This textbook is a practical guide to the application of the philosophy and principles of Integrative and Functional Medical Nutrition Therapy (IFMNT) in the practice of medicine, and the key role nutrition plays in restoring and maintaining wellness. The textbook provides an overview of recent reviews and studies of physiological and biochemical contributions to IFMNT and address nutritional influences in human heath overall, including poor nutrition, genomics, environmental toxicant exposures…
- Available Online
- View e-Book
- Other Authors
- Noland, Diana
- Drisko, Jeanne A.
- Wagner, Leigh
- Responsibility
- Diana Noland, Jeanne A. Drisko, Leigh Wagner, editors
- Place of Publication
- Cham
- Publisher
- Humana Press
- Date of Publication
- c2020
- Physical Description
- 1 online resource (xx, 1101 p.) : 230 illus., 200 illus. in color
- ISBN
- 9783030307301
- 9783030307295 (Print ed.)
- 9783030307318 (Print ed.)
- 9783030307325 (Print ed.)
- Subjects (MeSH)
- Chronic Disease - diet therapy
- Integrative Medicine
- Nutritional Physiological Phenomena
- Specialty
- Nutrition Therapy
- Abstract
- This textbook is a practical guide to the application of the philosophy and principles of Integrative and Functional Medical Nutrition Therapy (IFMNT) in the practice of medicine, and the key role nutrition plays in restoring and maintaining wellness. The textbook provides an overview of recent reviews and studies of physiological and biochemical contributions to IFMNT and address nutritional influences in human heath overall, including poor nutrition, genomics, environmental toxicant exposures, fractured human interactions, limited physical movement, stress, sleep deprivation, and other lifestyle factors. Ultimately, this textbook serves to help practitioners, healthcare systems, and policy makers better understand this different and novel approach to complex chronic disorders. It provides the reader with real world examples of applications of the underlying principles and practices of integrative/functional nutrition therapies and presents the most up-to-date intervention strategies and clinical tools to help the reader keep abreast of developments in this emerging specialty field. Many chapters include comprehensive coverage of the topic and clinical applications with supplementary learning features such as case studies, take-home messages, patient and practitioner handouts, algorithms, and suggested readings. Integrative and Functional Medical Nutrition Therapy: Principles and Practices will serve as an invaluable guide for healthcare professionals in their clinical application of nutrition, lifestyle assessment, and intervention for each unique, individual patient.
- Contents
- Part I. Global Healthcare Challenge of the 21st Century and the Future of Chronic Disease -- The History and Evolution of Medicine -- Influences of the Nutrition Transition on Chronic Disease -- Nutritional and Metabolic Wellness -- Nutritional Ecology and Human Health -- The Radial: Integrative and Functional MNT -- The Power of Listening and the Patient's Voice: 'Please Hear Me' -- Part II. Metabolic Characteristics and Mechanism of Chronic Disease -- Metabolic Correction Therapy: A Biochemical-Physiological Mechanisitc Explanation of Functional Medicine -- The Nutrition Assessment of Metabolic and Nutritional Balance -- IFMNT NIBLETS Nutrition Assessment Differential -- Nutritional Role of Fatty Acids -- Lipidomics: Clinical Application -- Structure: From Organelle and Cell Membrane to Tissue -- Protective Mechanisms and Susceptibility to Xenobiotic and Load -- Detoxification and Biotransformation -- Drug-Nutrient Interactions -- The Enterohepatic Circulation -- A Nutritional Genomics Approach to Epigenetic Influences on Chronic Disease -- Nutritional Influences on Methylation -- The Immune System: Our Body's Homeland Security Against Disease -- Allergy, Intolerance, and Sensitivity -- Infection: A Stealth Underlying Pathology of Chronic Disease -- Body Composition -- The Therapeutic Ketogenic Diet: Harnessing Glucose, Insulin, and Ketone Metabolism -- The GUT Immune System -- Centrality of the GI Tract to Overall Health and Functional Medicine Strategies for GERD, IBS, IBD -- The Microbiome and Brain Health -- The Role of Nutrition in Integrative Oncology -- The Microenvironment of Chronic Disease -- Chronic Pain -- Nutrition and Behavorial Health/Mental Health/Neurological Health -- Neurodevelopmental Disorders in Children -- Nutritional Influences on Hormonal Health -- Nutritional Influences on Reproduction: A Functional Approach -- Lifestyle Patterns of Chronic Disease -- Circadian Rhythm: Light-Dark Cycles -- Nutrition with Movement for Better Energy and Health. Mental, Emotional, and Spiritual Imbalances -- Part III. IFMNT Nutrition Care Process -- The IFMNT Practitioner -- The Patient Story and Relationship-Centered Care -- The Nutrition-Focused Physical Exam -- Modifiable Lifestyle Factors: Exercise, Sleep, Stress, Relationships -- Developing Interventions to Address Priorities: Food, Dietary Supplements, Lifestyle, and Referrals -- Therapeutic Diets -- Dietary Supplements: Understanding the Complexity of Use and Applications to Health -- Clinical Approaches to Monitoring and Evaluations of the Chronic Disease Client -- Ayurvedic Approach in Chronic Disease Management -- Part IV. Cases & Grand Rounds -- Cardiometabolic Syndrome -- Revolutionary New Concepts in the Prevention and Treatment of Cardiovascular Disease -- Immune System Under Fire: The Rise of Food Immune Reaction and Autoimmunity -- Amyotrophic Lateral Sclerosis (ALS): The Application of Integrative & Functional Medical Nutrition Therapy (IFMNT) -- Gastroenterology -- Respiratory -- The Skin, Selected Dermatologic Conditions and Medical Nutrition Therapy -- Movement Issues with Chronic Ill or Chronic Pain Patients -- Part V. Practitioner Practice Resources -- Systems Biology Resources -- Initial Nutrition Assessment Checklist -- Nutritional Diagnosis Resources -- Specialized Diets -- Motivational Interviewing -- Authorization for the Release of Information -- Patient Handouts.
- Format
- e-Book
- Location
- Online
Articular Cartilage of the Knee : Health, Disease and Therapy
https://libcat.nshealth.ca/en/permalink/provcat45489
Harpal K. Gahunia, Allan E. Gross, Kenneth P.H. Pritzker, Paul S. Babyn, Lucas Murnaghan, editors.
--New York, NY:
Springer
, c2020.
- Available Online
- View e-Book
- Location
- Online
Covering both pediatric and adult populations, this comprehensive text covers the diverse topics related to the health, disease and therapy of articular cartilage of the knee, from basic principles to future directions for research. This vast array of information is arranged into eight sections, encompassing a number of relevant disciplines and covering, in turn, normal articular cartilage, aging and degeneration, evaluation and assessment, non-surgical approaches, surgical approaches, qualitat…
- Available Online
- View e-Book
- Other Authors
- Gahunia, Harpal K.
- Gross, Allan E.
- Pritzker, Kenneth P.H.
- Babyn, Paul S.
- Murnaghan, Lucas
- Responsibility
- Harpal K. Gahunia, Allan E. Gross, Kenneth P.H. Pritzker, Paul S. Babyn, Lucas Murnaghan, editors
- Place of Publication
- New York, NY
- Publisher
- Springer
- Date of Publication
- c2020
- Physical Description
- 1 online resource (xxxviii, 498 p.) : 145 illus., 85 illus. in color
- ISBN
- 9781493975877
- 9781493975853 (Print ed.)
- 9781493975860 (Print ed.)
- Specialty
- Orthopedics
- Abstract
- Covering both pediatric and adult populations, this comprehensive text covers the diverse topics related to the health, disease and therapy of articular cartilage of the knee, from basic principles to future directions for research. This vast array of information is arranged into eight sections, encompassing a number of relevant disciplines and covering, in turn, normal articular cartilage, aging and degeneration, evaluation and assessment, non-surgical approaches, surgical approaches, qualitative and quantitative assessment of repair, research into cartilage repair and engineering, and future prospects for therapy. Each chapter is amply referenced and self-contained for independent study and reference. Scoring systems for knee cartilage assessment are included in four appendices as well, rounding out the presentation. A multidisciplinary collection of basic, translational and clinical material, Articular Cartilage of the Knee is a singular resource for orthopedic surgeons, rheumatologists, pathologists, scientists, tissue engineers and the broad spectrum of clinical professionals working with articular cartilage and its disorders.
- Contents
- Part I. Normal Articular Cartilage -- Structure and Function of Articular Cartilage -- Growth and Development of Articular Cartilage -- Part II. Aging, Degeneration and Physiologic Articular Cartilage Healing -- Articular Cartilage: Homeostasis, Aging and Degeneration -- Articular Cartilage Degradation: Biochemical Markers and Dynamic Loading -- Part III. Knee Articular Cartilage Injury: Evaluation and Assessment -- Acute and Chronic Traumatic Cartilage Injuries of the Knee -- Diagnostic Imaging of Knee Cartilage Injury: Evaluation and Assessment -- Assessment of Knee Cartilage Injury: Arthroscopic Evaluation and Classification -- Part IV. Repair of Knee Articular Cartilage Injury: Non-Operative Approach -- Physical and Rehabilitative Therapy for Knee Cartilage Injury and Disease -- Pharmacologic Agents for Knee Articular Cartilage Injury and Disease -- Part V. Repair of Knee Articular Cartilage: Surgical Approach -- Osteochondritis Dissecans of the Knee: Pathophysiology and Treatment -- Surgical Approach to Articular Cartilage Repair -- Clinical Outcome Assessment of Repaired Articular Cartilage -- Part VI. Qualitative and Quantitative Assessment of Articular Cartilage Repair -- Pre- and Post-Operative Imaging of Knee Articular Cartilage -- MRI of the Ultrastructural Composition of Articular Cartilage in Disease and Repair -- Histopathological Evaluation of Articular Cartilage Disease and Repair -- Part VII. Research in Cartilage Repair and Cartilage Engineering Strategies -- Human Derived Cells in Chondral or Osteochondral Repair -- Relevance of Engineered Scaffolds for Cartilage Repair -- Commercially Available Bio-Engineered Cartilage Grafts -- Part VIII. Future Prospects for Knee Articular Cartilage Therapy -- Knee Articular Cartilage: Future Directions for Research and Practice.
- Format
- e-Book
- Location
- Online
NAFLD and NASH : Biomarkers in Detection, Diagnosis and Monitoring
https://libcat.nshealth.ca/en/permalink/provcat45509
Manuel Romero-Gomez, editor.
--Cham:
Springer
, c2020.
- Available Online
- View e-Book
- Location
- Online
This book provides a comprehensive overview of the diagnosis and management of Non-alcoholic Fatty Liver Disease (NAFLD) and Non-Alcoholic Steatohepatis (NASH). Basic principles of disease progression, the genetic and nutritional basis of NAFLD and NASH are explained along with the proteomic principles underlying biomarker development. Chapters cover both biochemical and imaging biomarkers used in elastrography and ultrasound and discuss how these are applicable to early diagnosis and monitorin…
- Available Online
- View e-Book
- Other Authors
- Romero-Gomez, Manuel
- Responsibility
- Manuel Romero-Gomez, editor
- Place of Publication
- Cham
- Publisher
- Springer
- Date of Publication
- c2020
- Physical Description
- 1 online resource (x, 236 p.) : 18 illus., 17 illus. in color
- ISBN
- 9783030371739
- 9783030371722 (Print ed.)
- 9783030371746 (Print ed.)
- 9783030371753 (Print ed.)
- Subjects (MeSH)
- Biomarkers - analysis
- Diagnostic Techniques and Procedures
- Fatty Liver - diagnosis
- Non-alcoholic Fatty Liver Disease - diagnosis
- Specialty
- Diagnosis
- Gastroenterology
- Molecular Medicine
- Abstract
- This book provides a comprehensive overview of the diagnosis and management of Non-alcoholic Fatty Liver Disease (NAFLD) and Non-Alcoholic Steatohepatis (NASH). Basic principles of disease progression, the genetic and nutritional basis of NAFLD and NASH are explained along with the proteomic principles underlying biomarker development. Chapters cover both biochemical and imaging biomarkers used in elastrography and ultrasound and discuss how these are applicable to early diagnosis and monitoring of NASH and NAFLD. This is a useful resource for hepatologists, primary care providers with an interest in metabolic disease, diabetologists and endocrinologists in their daily clinical practice.
- Contents
- 1. The Spectrum of NAFLD: From the Organ to the System -- 2. Detection of NAFLD/NASH in the General Population and in Primary Care Clinics -- 3. Genes and NAFLD/NASH Progression -- 4. Geometry of Nutrition: Nutrients and NAFLD Progression -- 5. Biomarkers in Pediatric NAFLD -- 6. Biochemical Biomarkers of NAFLD/NASH -- 7. Non-invasive Assessment of Non-alcoholic Fatty Liver Disease: Ultrasound and Transient Elastography -- 8. MR Based-Imaging Biomarkers in NAFLD/NASH -- 9. Extracellular Vesicles in Non-alcoholic Fatty Liver Disease: Key Players in Disease Pathogenesis and Promising Biomarker Tools -- 10. From Transcriptomic to Metabolomic in the Development of Biomarkers in NAFLD/NASH -- 11. HCC in Patients with NAFLD/NASH -- 12. Psychological Biomarker Profile in NAFLD/NASH with Advanced Fibrosis -- 13. Integrative Proposal for the Use of Biomarkers in Clinical Practice Management of NAFLD/NASH.
- Format
- e-Book
- Location
- Online
Surgical Metabolism : The Metabolic Care of the Surgical Patient
https://libcat.nshealth.ca/en/permalink/provcat45533
Kimberly A. Davis, Stanley H. Rosenbaum, editors.
(Second edition)
--Cham:
Springer
, c2020.
- Available Online
- View e-Book
- Location
- Online
The goal of this book is not to follow a traditional systems or organ-based approach but rather to encourage our readers to think of the patients as complex biochemical systems. The book provides information that supplements the more traditional approaches and provides a detailed overview of the metabolic knowledge needed for surgical practice. The text reviews normal physiology, the pathophysiology of starvation and surgical stressors. It also focuses on appropriate nutritional repletion for v…
- Available Online
- View e-Book
- Other Authors
- Davis, Kimberly A.
- Rosenbaum, Stanley H.
- Responsibility
- Kimberly A. Davis, Stanley H. Rosenbaum, editors
- Edition
- Second edition
- Place of Publication
- Cham
- Publisher
- Springer
- Date of Publication
- c2020
- Physical Description
- 1 online resource (xxi, 373 p.) : 27 illus., 22 illus. in color
- ISBN
- 9783030397814
- 9783030397807 (Print ed.)
- 9783030397821 (Print ed.)
- 9783030397838 (Print ed.)
- Subjects (MeSH)
- Metabolic Diseases - physiopathology
- Metabolism - physiology
- Nutritional Physiological Phenomena
- Perioperative Care
- Abstract
- The goal of this book is not to follow a traditional systems or organ-based approach but rather to encourage our readers to think of the patients as complex biochemical systems. The book provides information that supplements the more traditional approaches and provides a detailed overview of the metabolic knowledge needed for surgical practice. The text reviews normal physiology, the pathophysiology of starvation and surgical stressors. It also focuses on appropriate nutritional repletion for various common disease states. Specifically, chapters address the severe metabolic demands created by systemic inflammation, infection, and major insults such as trauma and burns. All chapters are written by experts in their fields and include the most up-to-date scientific and clinical information. As biochemical aspects of modern medicine are advancing rapidly, chapters have been updated and several new chapters have been added in order to help readers keep pace in this race for state-of-the-art knowledge. Surgical Metabolism: The Metabolic Care of the Surgical Patient 2nd edition is designed for clinicians across levels of training and provides clear and concise evidence based guidelines for the metabolic management and nutritional support of the surgical patient.
- Contents
- Part I. Normal Metabolism -- Introduction to Metabolism -- Fluid and Electrolytes -- Acid–Base Physiology -- Metabolomics and Other “-Omic” Approaches to Characterize Perioperative Trajectories -- Part II. Global Perturbations of Metabolism -- Starvation -- Metabolism in the Trauma Patient -- Burns -- Obesity -- Malignancy -- Sepsis and Nutrition -- Intestinal Failure -- Part III. Metabolic Support and Nutrition Repletion -- Enteral Nutrition -- Parenteral Nutrition -- Immunonutrition and Supplementation: Pathways, Promise, and Pessimism -- Special Considerations in Organ Failure -- Endocrine Perturbations in Critical Illness -- Part IV. Thyroid and Parathyroid Disturbances -- The Microbiome, Surgical Stress, and Infection -- Special Considerations at the Extremes of Age.
- Format
- e-Book
- Location
- Online
Overtraining Syndrome in Athletes : A Comprehensive Review and Novel Perspectives
https://libcat.nshealth.ca/en/permalink/provcat45652
Flavio Cadegiani.
--Cham:
Springer
, c2020.
- Available Online
- View e-Book
- Location
- Online
This book discusses major changes in our understanding of the most prevalent non-orthopedic, sports-related condition – overtraining syndrome (OTS), arguing that it should be considered as the manifestation of burnout in athletes, rather than simply the result of excessive training. While the chronic adaptations of the cardiovascular and musculoskeletal systems to exercise are well documented, those of the endocrine system are less well known, and adaptations of the hormonal ranges for athletes…
- Available Online
- View e-Book
- Author
- Cadegiani, Flavio
- Responsibility
- Flavio Cadegiani
- Place of Publication
- Cham
- Publisher
- Springer
- Date of Publication
- c2020
- Physical Description
- 1 online resource (xxiv, 333 p.) : 67 illus., 28 illus. in color
- ISBN
- 9783030526283
- 9783030526276 (Print ed.)
- 9783030526290 (Print ed.)
- 9783030526306 (Print ed.)
- Subjects (MeSH)
- Athletic Performance - physiology
- Physical Conditioning, Human - physiology
- Physical Exertion - physiology
- Sports Medicine
- Specialty
- Sports Medicine
- Abstract
- This book discusses major changes in our understanding of the most prevalent non-orthopedic, sports-related condition – overtraining syndrome (OTS), arguing that it should be considered as the manifestation of burnout in athletes, rather than simply the result of excessive training. While the chronic adaptations of the cardiovascular and musculoskeletal systems to exercise are well documented, those of the endocrine system are less well known, and adaptations of the hormonal ranges for athletes are yet to be determined. There is also a lack of standardized diagnostic criteria, consistent assessment methods and biomarkers. This book offers a systematic review of the hormonal aspects of overtraining syndrome, and a comparison with sports-related syndromes triggered by chronic deprivation of different sorts, including the female athlete triad (and its derivative, RED-S) and burnout syndrome of the athlete (BSA). It demonstrates that these conditions, although studied separately from each other, may all be different manifestations of the same condition, leading to ‘maladaptive’ (dysfunctional forced adaptations to a hostile environment) changes in response to chronic depletion of energy and mechanisms of repair, causing multiple dysfunctions. The author proposes that OTS/Paradoxical Deconditioning Syndrome (PDS), RED-S/TRIAD and BSA are parts of a same condition, or at least a group of similar conditions. Further, the book offers a chronological overview of OTS, based on preliminary research. Given its broad scope, this concise reference book will appeal to a range of health professionals. It allows readers, including those without a strong academic background, to gain a systematic understanding of OTS.
- Contents
- 1. Introduction, Historical Perspective, and Basic Concepts on Overtraining Syndrome -- 2. Classical Understanding of Overtraining Syndrome -- 3. Methodological Challenges and Limitations of the Research on Overtraining Syndrome -- 4. New Findings on Overtraining Syndrome -- 5. Clinical, Metabolic, and Biochemical Behaviors in Overtraining Syndrome and Overall Athletes -- 6. New Understanding, Concepts, and Special Topics on Overtraining Syndrome -- 7. The Underappreciated Athlete: Overtraining Syndrome in Resistance Training, High-Intensity Functional Training (HIFT), and Female Athletes -- 8. Recovery from Overtraining Syndrome: Learnings from the EROS-Longitudinal Study -- 9. Female Athlete Triad (TRIAD), Relative Energy Deficiency of the Sport (RED-S), and Burnout Syndrome of the Athlete (BSA): Concepts, Similarities, and Differences from Overtraining Syndrome (OTS) -- 10. Special Topics on Overtraining Syndrome (OTS)/Paradoxical Deconditioning Syndrome (PDS) -- 11. Practical Approach to the Athlete Suspected or at High Risk for OTS -- 12. Research and Future Perspectives on Overtraining Syndrome -- 13. Clinical Hormonal Guidelines for the Research of the Endocrinology in Sports and Athletes: Beyond Overtraining Syndrome -- 14. Endocrinology of Physical Activity and Sport in Practice: How to Research? Models for the Chronology and Tests of Studies on Athletes -- 15. Novel Insights in Overtraining Syndrome: Summary and Conclusions.
- Format
- e-Book
- Location
- Online
Biochemistry, cell and molecular biology, and genetics : an integrated textbook
https://libcat.nshealth.ca/en/permalink/provcat46241
Zeynep Gromley, Adam Gromley.
--New York, NY:
Thieme
, c2020.
- Available Online
- View e-Book
- Location
- Online
- Available Online
- View e-Book
- Author
- Gromley, Zeynep
- Responsibility
- Zeynep Gromley, Adam Gromley
- Place of Publication
- New York, NY
- Publisher
- Thieme
- Date of Publication
- c2020
- Physical Description
- 1 online resource
- ISBN
- 9781626235359
- Subjects (MeSH)
- Biochemical Phenomena
- Genetic Phenomena
- Specialty
- Biochemistry
- Format
- e-Book
- Publication Type
- Examination Questions
- Outline
- Location
- Online
Medical biochemistry
https://libcat.nshealth.ca/en/permalink/provcat32898
editors John W. Baynes, Marek H. Dominiczak.
(5th ed.)
--Edinburgh, Scotland:
Elsevier
, c2019.
- Available Online
- View e-Book
- Access
- Registration required for PDF access.
- Location
- Online
Now fully revised, this acclaimed textbook efficiently links basic biochemistry with the day-to-day practice of medicine. You will learn basic science concepts and see them illustrated by clinical cases that describe patients you will likely encounter in your clinical training. You will also learn about the use of laboratory tests to diagnose and monitor the most important conditions. Brought to you in a thorough yet accessible manner, this new edition of Medical Biochemistry highlights the la…
- Available Online
- View e-Book
- Other Authors
- Baynes, John
- Dominiczak, Marek H
- Responsibility
- editors John W. Baynes, Marek H. Dominiczak
- Edition
- 5th ed.
- Alternate Title
- Biochemistry
- Place of Publication
- Edinburgh, Scotland
- Publisher
- Elsevier
- Date of Publication
- c2019
- Physical Description
- 1 online resource, 712 p.
- ISBN
- 9780702072994
- Subjects (MeSH)
- Biochemical Phenomena
- Biochemistry - methods
- Specialty
- Biochemistry
- Abstract
- Now fully revised, this acclaimed textbook efficiently links basic biochemistry with the day-to-day practice of medicine. You will learn basic science concepts and see them illustrated by clinical cases that describe patients you will likely encounter in your clinical training. You will also learn about the use of laboratory tests to diagnose and monitor the most important conditions. Brought to you in a thorough yet accessible manner, this new edition of Medical Biochemistry highlights the latest developments in regulatory and molecular biology, signal transduction, biochemistry and biomarkers of chronic disease, and bioinformatics and the '-omics'. It highlights the most important global medical issues: diabetes mellitus, obesity and malnutrition, cancer and atherosclerotic cardiovascular disease, and addresses the role of nutrition and exercise in medicine.
- Access
- Registration required for PDF access.
- Format
- e-Book
- Location
- Online
