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Fungal Infections of the Central Nervous System : Pathogens, Diagnosis, and Management

https://libcat.nshealth.ca/en/permalink/provcat44396
Mehmet Turgut, Sundaram Challa, Ali Akhaddar, editors. --Cham: Springer , c2019.
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Location
Online
This book provides comprehensive information on fungal infections of the central nervous system (CNS). Fungal infections are still a major public health challenge for most of the developing world and even for developed countries due to the rising numbers of immune compromised patients, refugee movements, and international travel. Although fungal infections involving the CNS are not particularly common, when they do occur, the results can be devastating in spite of recent advances and currently …
Available Online
View e-Book
Other Authors
Turgut, Mehmet
Challa, Sundaram
Akhaddar, Ali
Responsibility
Mehmet Turgut, Sundaram Challa, Ali Akhaddar, editors
Place of Publication
Cham
Publisher
Springer
Date of Publication
c2019
Physical Description
1 online resource (xii, 479 p.) : 162 illus., 85 illus. in color
ISBN
9783030060886
9783030060879 (Print ed.)
9783030060893 (Print ed.)
Subjects (MeSH)
Central Nervous System Fungal Infections
Specialty
Infectious Disease Medicine
Neurology
Abstract
This book provides comprehensive information on fungal infections of the central nervous system (CNS). Fungal infections are still a major public health challenge for most of the developing world and even for developed countries due to the rising numbers of immune compromised patients, refugee movements, and international travel. Although fungal infections involving the CNS are not particularly common, when they do occur, the results can be devastating in spite of recent advances and currently available therapies. Further, over the past several years, the incidence of these infections has seen a steep rise among immunodeficient patients. In this context, aggressive surgery remains the mainstay of management, but conservative antifungal drug treatment complemented by aggressive surgical debridement may be necessary. Yet the optimal management approach to fungal infections of the CNS remains controversial, owing to the limited individual experience and the variable clinical course of the conditions. Addressing that problem, this comprehensive book offers the ideal resource for neurosurgeons, neurologists and other specialists working with infectious diseases.
Contents
Part I: GENERAL CONSIDERATIONS -- Historical aspects of fungal infections -- Epidemiology of fungal infections -- Morphological classification of fungal infections (yeasts, molds, dimorphic) -- Pathogenesis of fungal infections -- Predisposing factors -- Histopathology -- Molecular genetics and genomics of fungal infections -- Part II: FUNGAL PATHOGENS: PATHOGENESIS, PATHOLOGY AND DIAGNOSIS -- Chapter 8: Aspergillosis -- Candidiasis -- Mucormycosis -- Histoplasmosis and coccidioidomycosis -- Cryptococcosis -- Blastomycosis and phaeohyphomycosis -- Onychomycosis -- epeat: initial; background-attachment: initial; background-origin: initial; background-clip: initial;">Emmonsiosis -- Cladophialophora bantiana -- Cladosporidium, Fusarium spp, Bipolaris hawaiiensis, Schizophyllum commune, Mycoplasma hominis, Scedosporium apiospermum -- Part III: CLINICAL SYNDROMES OF FUNGAL INFECTIONS INVOLVING CENTRAL NERVOUS SYSTEM AND ITS COVERINGS -- Meningitis and meningo-encephalitis -- Raised intracranial pressure -- Hydrocephalus -- Intracranial space occupying lesions -- Skull-base syndromes -- Orbito-rhino-cerebral syndrome -- Cavernous sinus syndrome -- Intracranial fungal aneurysms -- Acute ischemic or hemorrhagic stroke syndromes -- Spinal syndromes -- Part IV: RADIOLOGICAL FINDINGS OF FUNGAL INFECTIONS INVOLVING CENTRAL NERVOUS SYSTEM AND ITS COVERINGS -- Magnetic resonance imaging -- Positron emission tomography-computed tomography -- Imaging findings of fungal infections of the cranial and peripheral nerves -- Imaging findings of fungal infections of sinuses extending into brain -- Imaging findings of fungal infections of spine and spinal cord -- Part V: THERAPY OF FUNGAL INFECTIONS INVOLVING CENTRAL NERVOUS SYSTEM AND ITS COVERINGS -- Surgical therapy -- Prognosis of fungal infections involving the central nervous system and its coverings -- Part VI: FURTHER INSIGHTS INTO FUNGAL INFECTIONS -- Fungal infections of the spine mimicking tuberculosis -- Fungal infections in cancer patients -- Invasive fungal infections in patients with hematologic malignancies -- Fungal infections of central nervous system and their relationship to neuropsychiatric disorders -- Real-time PCR: advanced technologies and applications -- Next-generation sequencing: current technologies and applications -- Current innovations and future trends -- Conclusion.
Format
e-Book
Location
Online
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