Helicobacter pylori
https://libcat.nshealth.ca/en/permalink/provcat40402
Hidekazu Suzuki, Robin Warren, Barry Marshall, editors.
--Tokyo:
Springer Japan
, c2016.
- Available Online
- View e-Book
- Location
- Online
This book provides a detailed review of the most recent pathogenetic, diagnostic and therapeutic approaches in connection with Helicobacter pylori, along with priority areas in research and trends in clinical practice to address this significant pathogen acknowledged as the causative agent in a wide range of diseases, including gastric adenocarcinoma, MALT lymphoma and immune thrombocytopenic purpura (ITP). Medical authorities worldwide now recommend a "test and treat" strategy for this bacteri…
- Available Online
- View e-Book
- Other Authors
- Suzuki, Hidekazu
- Warren, Robin
- Marshall, Barry
- Responsibility
- Hidekazu Suzuki, Robin Warren, Barry Marshall, editors
- Place of Publication
- Tokyo
- Publisher
- Springer Japan
- Date of Publication
- c2016
- Physical Description
- 1 online resource (x, 267 p. : 43 illus., 26 illus. in color)
- ISBN
- 9784431557050
- 9784431557043 (print ed.)
- Subjects (MeSH)
- Helicobacter Infections - prevention & control
- Helicobacter pylori
- Abstract
- This book provides a detailed review of the most recent pathogenetic, diagnostic and therapeutic approaches in connection with Helicobacter pylori, along with priority areas in research and trends in clinical practice to address this significant pathogen acknowledged as the causative agent in a wide range of diseases, including gastric adenocarcinoma, MALT lymphoma and immune thrombocytopenic purpura (ITP). Medical authorities worldwide now recommend a "test and treat" strategy for this bacterial infection. Eradication therapy approaches range from general mass eradication therapy to tailor-made therapy for antibiotic-resistant refractory infection. In regions with high prevalence of H. pylori infection, the infection itself would be considered a major parameter to predict the risk of gastric adenocarcinoma development. The main interest has shifted recently to the risk stratification strategy for gastric cancer development and to the wide-ranging application of its serological prevention program. This book will benefit all gastroenterologists, hematologists, dermatologists, primary care doctors, epidemiologists, physicians who related with community hygiene, as well as basic scientists, particularly microbiologists, bacteriologists, pathologists, molecular biologists, biochemists, immunologists and oncologists.
- Contents
- Part I. History -- 1. Brief History of the Discovery of Helicobacter Pylori -- Part II. Pathogenesis -- 2. Human Migration -- 3. CagA -- 4. Helicobacter Pylori VacA Exhibits Pleiotropic Actions in Host Cells -- 5. Autophagy -- 6. Ghrelin and Gut Hormone -- 7. Symptom Generation -- 8. Gastric Non-Helicobacter Pylori Helicobacter: It's Significance in Human Gastric Diseases -- Part III. Diagnosis -- 9. Urea Breath Test & Rapid Urease Test -- 10. Endoscopic Findings of H. Pylori Infection -- 11. Gastric Cancer Risk stratification by H. pylori -- 12. Prevention of Gastric Cancer by Helicobacter Pylori Eradication: Current Evidence and Future Prospects -- Part IV. Treatment -- 13. Trends in Global Eradication Rates -- 14. Personalized Therapy in H. Pylori Eradication -- 15. Quadruple Regimens for Helicobacter Pylori Infection -- 16. Third-Line Eradication Therapy.
- Format
- e-Book
- Location
- Online
Helicobacter pylori
https://libcat.nshealth.ca/en/permalink/provcat40458
Nayoung Kim, editor.
--Singapore:
Springer
, c2016.
- Available Online
- View e-Book
- Location
- Online
This book presents the current state of knowledge regarding the ability of Helicobacter pylori to colonize the gastrointestinal tract, the global epidemiology of H. pylori infection, transmission routes, the pathophysiology of H. pylori-related gastroduodenal and other diseases, diagnosis and treatment methods, guidelines for eradication, antibiotic resistance, the reinfection rate after H. pylori eradication, and animal models of H. pylori or related Helicobacter infection. The aim is to equip…
- Available Online
- View e-Book
- Other Authors
- Kim, Nayoung
- Responsibility
- Nayoung Kim, editor
- Place of Publication
- Singapore
- Publisher
- Springer
- Date of Publication
- c2016
- Physical Description
- 1 online resource (x, 556 p. : 114 illus., 103 illus. in color)
- ISBN
- 9789812877062
- 9789812877055 (print ed.)
- Subjects (MeSH)
- Helicobacter Infections - prevention & control
- Helicobacter pylori
- Abstract
- This book presents the current state of knowledge regarding the ability of Helicobacter pylori to colonize the gastrointestinal tract, the global epidemiology of H. pylori infection, transmission routes, the pathophysiology of H. pylori-related gastroduodenal and other diseases, diagnosis and treatment methods, guidelines for eradication, antibiotic resistance, the reinfection rate after H. pylori eradication, and animal models of H. pylori or related Helicobacter infection. The aim is to equip readers around the world with the understanding required in order to implement effective methods of H. pylori eradication and to enhance clinical outcomes for patients. The text is clearly written and is complemented by many helpful illustrations. This book will be a great asset in clinical practice for all practitioners who are involved in caring for patients with H. pylori-related diseases or have an interest in the subject. It will also be a useful source of information for medical students and for intelligent laypeople seeking information on H. pylori.
- Contents
- [publisher supplied] Part 1. Epidemiology -- Prevalence and Transmission routes of H. pylori -- Part 2. Pathophysiology -- 1) Colonization of H. pylori in the stomach -- 2) Brief description of Pathophysiology -- 3) Immune mechanism -- 4) Change of acid secretion, ghrelin and leptin by H. pylori -- 5) H. pylori virulence factors -- A: toxin (CagA, VacA, DupA, OipA, IceA) -- B: genetic polymorphism of toxin and disease -- 6) Host factors: genetic polymorphism, etc -- Part 3. Diagnosis -- 1) Serology -- 2) Histology -- 3) Culture -- 4) UBT -- 5) Stool antigen -- 6) Specific conditions -- A: Children -- B: Bleeding -- Part 4. Symptom -- 1)Symptom of acute and chronic H. pylori infection -- Part 5. Disease -- 1) Atrophic gastritis and Intestinal metaplasia -- 2) Functional dyspepsia -- 3) Peptic ulcer -- 4) MALToma -- 5) Gastric cancer -- A: Synopsis and Epidemiology of gastric cancer -- B1: Pathogenesis: i.Genetic alternation (mutations in tumor-related genes) induced by Activation-induced cytidine deaminase (AID) -- B2: Pathogenesis: ii. Epigenetic mechanisms: aberrant DNA methylation, microRNA -- B3: Pathogenesis:iii. Macrophage inhibitory factor (MIF) -- B4: Pathogenesis: iv. Epidermal mesenchyme transition (EMT) -- B5: Pathogenesis: v. ABO blood type -- B6: Pathogenesis: vi. First relatives of gastric cancer -- C: H. pylori-negative gastric cancer -- 6) Gastroesophageal reflux disease (GERD) -- 7) NSAID-induced gastropathy and H. pylori infection -- 8) Extraintestinal manifestations of H. pylori infection -- A: Iron deficiency anemia -- B: Idiopathic thrombocytopenic purpura -- C: Heart disease -- D: Atopy and allergy -- Part 6. Antibiotic resistance -- 1) Synopsis of antibiotic resistance -- 2) Clarithromycin -- 3) Amoxicillin -- 4) Quinolone -- 5) Metronidazole -- Part 7. Treatment -- 1) Synopsis of antibiotic treatment -- 2) Triple therapy -- 3) Quadruple therapy -- 4) Sequential therapy -- 5) Concomitant therapy -- 6) Tailored therapy based on antibiotic resistance -- 7) Levofloxacin or rifabutin based triple therapy -- 8) Probiotics -- 9) Treatment guidelines -- 10) Screening method of early gastric cancer -- 11) Recrudescence and reinfection -- Part 8. Consequences of H. pylori eradication -- 1) Peptic ulcer disease -- 2) atrophic gastritis and Intestinal metaplasia -- 3) Gastric cancer -- Part 9. The effect of H. pylori on the other microbiota of stomach -- The effect of H. pylori on the other microbiota of stomach -- Part 10. Animal model- H. pylori, H. felis.
- Format
- e-Book
- Location
- Online
