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Clinical Applications of Nuclear Medicine Targeted Therapy

https://libcat.nshealth.ca/en/permalink/provcat42889
edited by Emilio Bombardieri, Ettore Seregni, Laura Evangelista, Carlo Chiesa, Arturo Chiti. --Cham: Springer , c2018.
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This book offers a practical and modern update on radioisotope therapy. Clinically oriented, it provides a thorough guide to patient management, with the latest indications and procedures for the current radioisotopic treatments. It addresses the clinical problems associated with each respective pathology, discussing the management of patients (diagnosis and non-radioisotope therapy), the radiopharmaceuticals available today, and the current radioisotopic procedures. Wherever possible, informat…
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Other Authors
Bombardieri, Emilio
Seregni, Ettore
Evangelista, Laura
Chiesa, Carlo
Chiti, Arturo
Responsibility
edited by Emilio Bombardieri, Ettore Seregni, Laura Evangelista, Carlo Chiesa, Arturo Chiti
Place of Publication
Cham
Publisher
Springer
Date of Publication
c2018
Physical Description
1 online resource (xiv, 503 p.) : 108 illus., 73 illus. in color
ISBN
9783319630670
9783319630663 (print ed.)
9783319630687 (print ed.)
Subjects (MeSH)
Nuclear Medicine - methods
Radioisotopes - therapeutic use
Radiopharmaceuticals - therapeutic use
Radiotherapy - methods
Specialty
Radiotherapy
Abstract
This book offers a practical and modern update on radioisotope therapy. Clinically oriented, it provides a thorough guide to patient management, with the latest indications and procedures for the current radioisotopic treatments. It addresses the clinical problems associated with each respective pathology, discussing the management of patients (diagnosis and non-radioisotope therapy), the radiopharmaceuticals available today, and the current radioisotopic procedures. Wherever possible, information on dosimetry is included at the end of each topic, together with a list of and comments on the most recent guidelines with their recommendations for radiometabolic therapy. The book is divided into six main sections: thyroid diseases, hepatic tumors (HCC and hepatic metastases), bone metastases from prostate cancer, lymphomas, and neuroendocrine tumors. The last section is dedicated to new perspectives of radioisotope treatment. Based on contributions from of a multidisciplinary team of specialists: oncologists, surgeons, endocrinologists, hematologists, urologists, radiopharmacists and nuclear medicine physicians, it provides a comprehensive analysis of the position of radioisotope treatments among the various therapeutic options. Readers interested in targeted therapy, radiometabolic therapy, radioimmunotherapy and radiometabolic imaging will find this book both informative and insightful.
Contents
THYROID DISEASES -- Diagnosis and treatment of hyperthyroidism (Endocrinologist) -- Radiopharmaceuticals for therapy of thyroid diseases ( chemistry, mechanism of uptake, biodistribution, doses) (Radiochemist) -- Radioiodine therapy of hyperthyroidism (indications , procedures and results) ( Nucl Medicine Physician) -- Dosimetry (Physicist) -- Clinical management of thyroid cancer (Oncologist) -- Radioidine therapy of thyroid cancer (ablation, loco-regional and distant metastases, indications procedures and results) (Nucl Medicine Physician) -- Dosimetry (Physicist) -- Novel approaches of radiometabolic treatment of thyroid cancer (Nucl Medicine Physician) -- Published guidelines on radioisotopic treatments of thyroid diseases (Nucl Medicine Physician and Oncologist) -- HEPATIC CANCER -- Clinical options for treatment of hepatocellular carcinoma (HCC) (Oncologist, Surge on) -- Radiopharmaceuticals for radioembolization (characteristics, mechanism of uptake, biodistribution, doses) (Radiochemist) -- HCC radioembolization with 90Y microspheres (indications and procedures) (Nucl Medicine Physician) -- Dosimetry (Physicist) -- The clinical problem of hepatic metastases (Oncologist, Surgeon) -- Radioembolization of hepatic metastases with 90Y microspheres (indications and procedures) (Nucl Medicine Physician) -- Dosimetry (Physicist) -- Published guidelines on radioisotope treatment of hepatocellular cancer (Nucl Medicine Physician and Oncologist) -- NEUROENDOCRINE TUMORS -- Radiopharmaceuticals for treatment of neuroendocrine tumors (mechanisn of action, biodistribution, doses) (Radiochemis inPaediatric tumors of neuroendocrine origin (Oncologist) -- Treatment with 131I—MIBG (indications procedures and results) (Nucl Medicine Physician) -- Dosimetry (Physicist) -- GEP neuroendocrine tumors (Oncologist) -- PPRT with 90Y labeled peptides (indications ,procedures and results) (Nucl Medicine Physician) -- Dosimetry (Physicist) -- Published guidelines on radioisotope treatment of Neuroendocrine tumors(Nucl Medicine Physician and Oncologist) -- LYMPHOMAS -- Selection of lymphoma patients candidates for Radioimmunotherapy (Haematologist) -- Radiopharmaceuticals for treatment of neuroendocrine tumors (mechanisn of action, biodistribution, doses) (Radiochemist) -- Treatment with anti-CD20 Antibodies ( 90Y- ibritumomab /131 I- Tositumomab) (indications and procedures and results) (Nucl Medicine Physician) -- Radioimmunotherapy at high doses of lymphomas (Nucl Medicine Physician) -- Published guidelines on radioisotope treatment of Lymphomas (Nucl Medicine Physician and Oncologist) -- PROSTATE CANCER -- Overview on bone metastases from prostate cancer (Urologist, Oncologist) -- Radiopharmaceuticals for treatment of bone metastases (mechanisn of action, biodistribution, doses) (Radiochemist) -- Targeted therapy with 223Ra dichloride of bone metastases(Nucl Medicine Physician) -- Novel approaches of treatment with 223Ra based targeted therapy (Nucl Medicine Physician) -- Dosimetry (Physicist) -- Published guidelines on radioisotope treatment of Bone Metastases (Nucl Medicine Physician and Oncologist).
Format
e-Book
Location
Online
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Thoraco-Abdominal Aorta : Surgical and Anesthetic Management

https://libcat.nshealth.ca/en/permalink/provcat28262
edited by Roberto Chiesa, Germano Melissano, Alberto Zangrillo. --Milan: Springer , c2011.
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Online
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Author
Chiesa, Roberto
Other Authors
Melissano, Germano
Zangrillo, Alberto
Responsibility
edited by Roberto Chiesa, Germano Melissano, Alberto Zangrillo
Place of Publication
Milan
Publisher
Springer
Date of Publication
c2011
ISBN
9788847018570
Subjects (MeSH)
Aorta, Thoracic - surgery
Aorta, Abdominal - surgery
Vascular Surgical Procedures - methods
Subjects (LCSH)
Vascular Surgery
Format
e-Book
Location
Online
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Visceral Vessels and Aortic Repair : Challenges and Difficult Cases

https://libcat.nshealth.ca/en/permalink/provcat44048
Yamume Tshomba, Domenico Baccellieri, Roberto Chiesa, editors. --Cham: Springer , 2019.
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This book shows how new technologies and technical skills together with deeper understanding of pathophysiology of visceral and renal ischemia have contributed to significant improvements in the clinical outcomes in patients undergoing complex aortic repair involving splanchnic arteries. In recent years, aortic repair has expanded its borders, focusing more and more on the particularly challenging segments from which critical branches originate. Optimal results in this area are obtained through…
Available Online
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Other Authors
Tshomba, Yamume
Baccellieri, Domenico
Chiesa, Roberto
Responsibility
Yamume Tshomba, Domenico Baccellieri, Roberto Chiesa, editors
Place of Publication
Cham
Publisher
Springer
Date of Publication
2019
Physical Description
1 online resource (xi, 421 p.) : 222 illus., 192 illus. in color
ISBN
9783319947617
9783319947600 (Print ed.)
9783319947624 (Print ed.)
Subjects (MeSH)
Aorta - physiopathology
Aortic Diseases - surgery
Vascular Surgical Procedures
Specialty
Cardiovascular Surgical Procedures
Abstract
This book shows how new technologies and technical skills together with deeper understanding of pathophysiology of visceral and renal ischemia have contributed to significant improvements in the clinical outcomes in patients undergoing complex aortic repair involving splanchnic arteries. In recent years, aortic repair has expanded its borders, focusing more and more on the particularly challenging segments from which critical branches originate. Optimal results in this area are obtained through a multidisciplinary approach based on crucial elements such as sophisticated imaging techniques, advanced anesthesiological and pharmacological strategies, as well as updated surgical techniques and devices able to reduce ischemic injuries. The book presents problems tackled from different perspectives, by analyzing the main technical aspects of the surgical technique but also functional and metabolic issues. It also discusses concepts such as ischemic preconditioning and ischemia-reperfusion mechanisms, as well as innovative investigational approaches. In the “endovascular era”, it highlights the most recent updates in complex endovascular repair involving renal and visceral arteries, providing both practical tips and tricks and outcomes analyses. The volume also addresses specific, rarely reported problems in vascular surgery, including issues in renal transplant, oncologic surgery with involvement of splanchnic arteries and of the vena cava, and use of the deep veins in aortic surgery. This volume represents a powerful tool for both young and experienced operators who wish to approach the complex aortic pathology either by open surgery or through endovascular methods.”.
Contents
Anatomical overview and imaging of the aorta and visceral arteries -- Physiopathology and anaesthesiological management of supravisceral aortic clamping -- Perioperative renal pharmacological protection during cardiovascular surgery -- Renal protection during open aortic surgery with Custodiol solution -- Renal artery stenosis associated with aortic disease: timing and outcomes of operative management -- Renal arteries anatomic abnormalities during open abdominal aortic repair -- Renal transplantation and aortic disease: operative management -- Pulsatile perfusion of kidney allografts -- Endovascular aortic repair: the renal side of the story -- Challenging infrarenal aortic necks in EVAR: devices evolution, long-term results and new concepts -- Open repair of pararenal aneurysms: renal vessels surgical management -- Endovascular repair of pararenal aortic aneurysms: the management of visceral arteries with fenestrated technology -- Emergency kit for chimney technique for ruptured abdominal aortic aneurysm -- Current treatment options for complex aortic pathology with visceral arteries involvement between open and endo: single center experience -- Aortic “coral reef” with visceral arteries involvement: treatment options -- Thoracoabdominal aortic aneurysm open repair: visceral arteries reattachment strategies -- Sutureless anastomosis during thoracoabdominal aortic repair -- Tissue ischemia during aortic surgery. The point of view of the perfusionist -- Ischemic preconditioning: the rationale and evidence based outcomes -- Intraoperative neurophysiologic monitoring during aortic surgery: basic principles and clinical experience -- Long-term patency of visceral vessels after thoracoabdominal aortic repair -- Fate of Carrel patch after thoracoabdominal aortic repair: treatment options for recurrent aneurysms -- Total endovascular repair of thoracoabdominal aortic aneurysms: lessons learned -- The SpiderGraft for Thoracoabdominal Aortic Repair: rationale and indications -- Visceral ischemia during type B dissection: incidence, prognostic value, diagnosis and operative management -- Visceral ischemia during acute type B dissection: limits of current approaches and new perspective -- Epidemiology, diagnosis and clinical management of arteritis involving visceral vessels -- Visceral arteries involvement in Takayasu patients: treatment options -- Aortic infection with visceral arteries involvement in the endovascular era: treatment options -- Deep vein reconstruction for infective aortic syndromes with visceral arteries involvement -- Vena cava oncologic surgery -- Rerouting of visceral arteries during hybrid thoracoabdominal aortic repair: a still useful solution in highly selected case.
Format
e-Book
Location
Online
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