Autophagy Networks in Inflammation
https://libcat.nshealth.ca/en/permalink/provcat40154
Maria Chiara Maiuri, Daniela De Stefano, editors.
--Cham:
Springer
, c2016.
- Available Online
- View e-Book
- Location
- Online
Autophagy principally serves an adaptive function to protect organisms against diverse human pathologies, including cancer and neurodegeneration. Recent developments using in vitro, ex vivo and in vivo models show the involvement of the autophagy pathway in immunity and inflammation. Moreover, direct interactions between autophagy proteins and immune signalling molecules have also been demonstrated. Defects in autophagy - similar to cancer, neurodegenerative diseases and aging - through autopha…
- Available Online
- View e-Book
- Other Authors
- Maiuri, Maria Chiara
- De Stefano, Daniela
- Responsibility
- Maria Chiara Maiuri, Daniela De Stefano, editors
- Place of Publication
- Cham
- Publisher
- Springer
- Date of Publication
- c2016
- Physical Description
- 1 online resource (xv, 403 p. : 20 illus., 16 illus. in color)
- Series Title
- Progress in inflammation research
- ISBN
- 9783319300795
- 9783319300771 (print ed.)
- Subjects (MeSH)
- Autophagy
- Inflammasomes
- Inflammation - physiopathology
- Inflammation - therapy
- Abstract
- Autophagy principally serves an adaptive function to protect organisms against diverse human pathologies, including cancer and neurodegeneration. Recent developments using in vitro, ex vivo and in vivo models show the involvement of the autophagy pathway in immunity and inflammation. Moreover, direct interactions between autophagy proteins and immune signalling molecules have also been demonstrated. Defects in autophagy - similar to cancer, neurodegenerative diseases and aging - through autophagy gene mutation and/or microbial antagonism, may underlie the pathogenesis of many infectious diseases and inflammatory syndromes. In spite of the increasing awareness of the importance of autophagy in these pathophysiological conditions, this process remains underestimated and is often overlooked. As a consequence, its role in the initiation, stability, maintenance, and progression of these diseases are still poorly understood. This book reviews the recent advances regarding the functions of the autophagy pathway and autophagy proteins in immunity and inflammation, focusing on their role in self-nonself distinction, their implications in innate and adaptive immune responses and their dysregulation in the pathology of certain inflammatory and autoimmune diseases.
- Contents
- [publisher supplied] Autophagy in direct pathogen elimination (Xenophagy) -- Autophagy and pattern recognition receptors -- Autophagy and inflammasomes -- Autophagy and Antigen presentation -- Autophagy and regulation of T and B cell function -- Autophagy in chronic inflammation -- The complex crosstalk between autophagy and ROS -- Lipophagy -- Autophagy, phagocytosis and entosis: who eats whom? -- Which is the cell fate of inflammatory cells? Autophagic cell death, pyroptosis, netosis, apoptosis, necrosis -- Host defence (virus/bacteria) -- Neurological diseases -- Pulmonary diseases (emphysema, COPD, etc.) -- Inflammatory bowel disease -- Target autophagy as a novel therapeutic strategy in autoimmune diseases -- Liver and pancreatic diseases -- Obesity -- Aging -- Overview on clinical trials.
- Format
- e-Book
- Location
- Online
Biomarkers of Cardiometabolic Risk, Inflammation and Disease
https://libcat.nshealth.ca/en/permalink/provcat39237
Filipe Palavra, Fl©vio Reis, Daniela Marado, Armando Sena, editors.
--Cham:
Springer
, c2015.
- Available Online
- View e-Book
- Location
- Online
This book discusses recent advances in the area of cardiometabolic risk biomarkers of chronic inflammatory and cardiovascular disorders. Tackling the topic in a systematic manner, the book starts with an introduction to cardiometabolic risk and its clinical relevance, comparing emergent and classical biomarkers. It then goes on to discuss cardiometabolic risk biomarkers in a range of diseases, including diabetes, ischemic stroke and neurodegenerative disorders. Biomarkers of Cardiometabolic Ris…
- Available Online
- View e-Book
- Other Authors
- Palavra, Filipe
- Reis, Fl©vio
- Marado, Daniela
- Sena, Armando
- Responsibility
- Filipe Palavra, Fl©vio Reis, Daniela Marado, Armando Sena, editors
- Place of Publication
- Cham
- Publisher
- Springer
- Date of Publication
- c2015
- Physical Description
- 1 online resource (x, 165 p. : 11 illus. in color)
- ISBN
- 9783319160184
- 9783319160177 (print ed.)
- Subjects (MeSH)
- Biomarkers
- Cardiovascular Diseases - diagnosis
- Inflammation
- Risk Factors
- Abstract
- This book discusses recent advances in the area of cardiometabolic risk biomarkers of chronic inflammatory and cardiovascular disorders. Tackling the topic in a systematic manner, the book starts with an introduction to cardiometabolic risk and its clinical relevance, comparing emergent and classical biomarkers. It then goes on to discuss cardiometabolic risk biomarkers in a range of diseases, including diabetes, ischemic stroke and neurodegenerative disorders. Biomarkers of Cardiometabolic Risk, Inflammation and Disease is aimed at doctors specializing in internal medicine, neurology, cardiology, rheumatology, nephrology or endocrinology and will also be of interest to GPs, trainee doctors, and clinical and basic researchers working on cardiovascular and autoimmune disorders.
- Contents
- Inflammation biomarkers and cardiometabolic risk -- Cardiovascular disease -- Diabetes mellitus and metabolic syndrome -- Ischemic stroke -- Chronic kidney disease -- Immune-mediated inflammatory rheumatic diseases -- Cardiometabolic risk, inflammation and neurodegenerative disorders.
- Format
- e-Book
- Location
- Online
Cancer Research and Clinical Trials in Developing Countries : A Practical Guide
https://libcat.nshealth.ca/en/permalink/provcat39793
Daniela Cristina Stefan, editor.
--Cham:
Springer
, c2016.
- Available Online
- View e-Book
- Location
- Online
This book describes the principles around which cancer research and clinical trials can be developed. Additionally, by describing the particularities of planning and implementing cancer research in developing countries, this book provides valuable practical information for researchers in resource-rich countries who contemplate cooperating with scientists from limited-resource countries in performing research.Written and edited by leaders in the field who work in these developing countries, Canc…
- Available Online
- View e-Book
- Other Authors
- Stefan, Daniela Cristina
- Responsibility
- Daniela Cristina Stefan, editor
- Place of Publication
- Cham
- Publisher
- Springer
- Date of Publication
- c2016
- Physical Description
- 1 online resource (xi, 218 p. : 18 illus., 8 illus. in color)
- ISBN
- 9783319184432
- 9783319184425 (print ed.)
- Subjects (MeSH)
- Biomedical Research
- Clinical Trials as Topic
- Developing Countries
- Neoplasms
- Abstract
- This book describes the principles around which cancer research and clinical trials can be developed. Additionally, by describing the particularities of planning and implementing cancer research in developing countries, this book provides valuable practical information for researchers in resource-rich countries who contemplate cooperating with scientists from limited-resource countries in performing research.Written and edited by leaders in the field who work in these developing countries, Cancer Research and Clinical Trials in Developing Countries: A Practical Guide will appeal to a wide range of researchers, students, and physicians who are engaging in cancer research and clinical trials. It focuses on methodology and statistics while structured around the needs of cancer research. It provides valuable information regarding international collaboration, funding mechanisms as well as publishing and dissemination of research findings.
- Contents
- 1.Introduction: the need to conduct cancer research in developing countries -- 2. Steps of a research study: from research question to publication -- 3. Types of research designs -- 4. Clinical research in developing countries: An overview -- 5. The research protocol -- 6. Ethics of conducting cancer research in developing countries -- 7. Data management and statistics -- 8. Funding For Cancer Research and Clinical Studies in Low and Middle-Income Countries -- 9. International Collaboration in Cancer Research -- 10. Publication and dissemination of research findings.
- Format
- e-Book
- Location
- Online
Community Wayfinding: Pathways to Understanding
https://libcat.nshealth.ca/en/permalink/provcat40185
Rebecca H. Hunter, Lynda A. Anderson, Basia L. Belza, editors.
--Cham:
Springer
, c2016.
- Available Online
- View e-Book
- Location
- Online
This book examines wayfinding from a broad public health perspective and articulates what needs to be done to create better wayfinding for all people regardless of age, ability, or mode of transportation. Addressing both science and the human experience, the book brings together a group of international experts to examine community wayfinding from a variety of viewpoints. It first presents a critical foundation for understanding wayfinding from an individual perspective. Next, it describes rele…
- Available Online
- View e-Book
- Other Authors
- Hunter, Rebecca H
- Anderson, Lynda A
- Belza, Basia L
- Responsibility
- Rebecca H. Hunter, Lynda A. Anderson, Basia L. Belza, editors
- Place of Publication
- Cham
- Publisher
- Springer
- Date of Publication
- c2016
- Physical Description
- 1 online resource (xiv, 282 p. : 57 illus.)
- ISBN
- 9783319310725
- 9783319310701 (print ed.)
- Subjects (MeSH)
- Architecture as Topic
- City Planning
- Environment Design
- Environment
- Orientation
- Space Perception
- Spatial Behavior
- Abstract
- This book examines wayfinding from a broad public health perspective and articulates what needs to be done to create better wayfinding for all people regardless of age, ability, or mode of transportation. Addressing both science and the human experience, the book brings together a group of international experts to examine community wayfinding from a variety of viewpoints. It first presents a critical foundation for understanding wayfinding from an individual perspective. Next, it describes relevant design principles and practices by drawing upon architecture, environmental graphic design, universal design (UD), and urban planning. The book then goes on to examine wayfinding tools and innovative technologies ranging from maps to apps to complex systems. In addition, coverage includes case studies, lessons from wayfinding improvement initiatives, and recommendations for future research, practice, and policy. Overall, the book focuses on the economic and commercial benefits of good wayfinding, its potential impact on the health of individuals and communities, as well as strategies for the journey ahead. It will appeal to numerous professionals across many disciplines from architecture and cartography to public health and urban planning. Additionally, the book can help advance a dialogue among those interested in enhancing the livability of their communities.
- Contents
- Part I. Foundations of Wayfinding -- 1. Introduction to Community Wayfinding / Rebecca H. Hunter, Lynda A. Anderson, Basia Belza -- 2. Human Wayfinding: Integration of Mind and Body / Anna E. Vandenberg -- Part II. The Community Environment and Wayfinding -- 3. The Space Syntax of Intelligible Communities / John Peponis -- 4. Legibility and Continuity in the Built Environment / Michael R. King and Elise de Jong -- 5. Design for All Users / Jon A. Sanford -- 6. The Challenge of Wayfinding in Health Care Environments / Per Mollerup -- Part III. Tools and Technology -- 7. Maps in the Head and Tools in the Hand: Wayfinding and Navigation in a Spatially Enabled Society / Toru Ishikawa -- 8. Maps to Apps: Evaluating Wayfinding Technology / Sean P. Mullen, Daniel E. Palac and Lucinda L. Bryant -- 9. Wayfinding, Mobility, and Technology for an Aging Society / Marlon Maus, David A. Lindeman and William A Satariano -- Part IV. Practice and Policy -- 10. Promoting Walking via Ease of Wayfinding / Chanam Lee -- 11. Bridging the Gap: Increasing Access Through Training and Technology / Rachel Beyerle and Julie E. Dupree -- 12. Transportation Systems and Wayfinding / Edward R. Stollof -- 13. The Role of Advocacy / Scott Bricker -- Part V. Integrative Perspectives -- 14. Linking Wayfinding and Wayfaring / Ditte Bendix Lanng and Ole B. Jensen -- 15. The Journey Forward / Rebecca H. Hunter, Steven P. Hooker and Daniela B. Friedman -- Index.
- Format
- e-Book
- Location
- Online
Dermatopathology
https://libcat.nshealth.ca/en/permalink/provcat40149
Daniela Massi, editor.
--Cham:
Springer
, c2016.
- Available Online
- View e-Book
- Location
- Online
This book covers the complete field of dermatopathology - from Acantholysis to Xeroderma pigmentosum. The alphabetically arranged entries, each of which provides a detailed description of a specific pathological disease pattern, allow readers to quickly and easily find the information they need.
- Available Online
- View e-Book
- Other Authors
- Massi, Daniela
- Responsibility
- Daniela Massi, editor
- Place of Publication
- Cham
- Publisher
- Springer
- Date of Publication
- c2016
- Physical Description
- 1 online resource (xix, 367 p. : 310 illus., 306 illus. in color).
- Series Title
- Encyclopedia of pathology
- ISBN
- 9783319300061
- 9783319300054 (print ed.)
- ISSN
- 2366-6269
- Subjects (MeSH)
- Skin Diseases
- Skin - pathology
- Abstract
- This book covers the complete field of dermatopathology - from Acantholysis to Xeroderma pigmentosum. The alphabetically arranged entries, each of which provides a detailed description of a specific pathological disease pattern, allow readers to quickly and easily find the information they need.
- Format
- e-Book
- Publication Type
- Encyclopedia
- Location
- Online
Esophageal Cancer : Diagnosis and Treatment
https://libcat.nshealth.ca/en/permalink/provcat42604
Francisco Schlottmann, Daniela Molena, Marco G. Patti, editors.
--Cham:
Springer
, c2018.
- Available Online
- View e-Book
- Location
- Online
This book provides comprehensive and practical guidance for the management of esophageal cancer. It presents a detailed review of the pathophysiology, clinical staging, treatment, and outcomes of patients with esophageal cancer. Chapters cover the epidemiology of the disease, latest diagnostic and staging tools, systemic therapies, and the current open and minimally invasive surgical techniques including transhiatal, Ivor Lewis and McKeown esophagectomy. Esophageal Cancer: Diagnosis and Treatme…
- Available Online
- View e-Book
- Other Authors
- Schlottmann, Francisco
- Molena, Daniela
- Patti, Marco G.
- Responsibility
- Francisco Schlottmann, Daniela Molena, Marco G. Patti, editors
- Place of Publication
- Cham
- Publisher
- Springer
- Date of Publication
- c2018
- Physical Description
- 1 online resource (xiv, 209 p.) : 99 illus., 84 illus. in color
- ISBN
- 9783319918303
- 9783319918297 (print ed.)
- 9783319918310 (print ed.)
- Subjects (MeSH)
- Esophageal Neoplasms - diagnosis
- Esophageal Neoplasms - therapy
- Specialty
- Gastroenterology
- Medical Oncology
- Abstract
- This book provides comprehensive and practical guidance for the management of esophageal cancer. It presents a detailed review of the pathophysiology, clinical staging, treatment, and outcomes of patients with esophageal cancer. Chapters cover the epidemiology of the disease, latest diagnostic and staging tools, systemic therapies, and the current open and minimally invasive surgical techniques including transhiatal, Ivor Lewis and McKeown esophagectomy. Esophageal Cancer: Diagnosis and Treatment compiles experience gained across a variety of medical disciplines, with contributions from world renowned surgeons, gastroenterologists, and medical oncologists. Thanks to its multidisciplinary authorship, this book represents a unique resource for anybody who takes care of patients with esophageal cancer.
- Contents
- 1. Esophageal Anatomy -- 2. Esophageal Squamous Cell Cancer: Pathogenesis and Epidemiology -- 3. Esophageal Adenocarcinoma: Pathogenesis and Epidemiology -- 4. Staging of Esophageal Cancer: Implications for Therapy -- 5. Endoscopic Therapy for Superficial Esophageal Cancer -- 6. Neoadjuvant and Adjuvant Therapy -- 7. Restaging after Neoadjuvant Therapy -- 8. Anesthetic Concerns for Esophageal Surgery -- 9. Transhiatal Esophagectomy -- 10. Ivor Lewis Esophagectomy -- 11. McKeown Esophagectomy -- 12. En Bloc Esophagectomy -- 13. Fundamentals of Minimally Invasive Esophagectomy -- 14. Minimally Invasive Ivor Lewis Esophagectomy -- 15. Hybrid Esophagectomy -- 16. Colonic Interposition after Esophagectomy -- 17. Perioperative Care and Management of Post-operative Complications -- 18. Volume and Outcomes in Esophageal Cancer Surgery -- 19. Quality of Life after Esophagectomy -- 20. Palliative Treatment of Esophageal Cancer -- 21. Future Directions in Esophageal Cancer.
- Format
- e-Book
- Location
- Online
Features and Management of the Pelvic Cancer Pain
https://libcat.nshealth.ca/en/permalink/provcat40248
Marco Cascella, Arturo Cuomo, Daniela Viscardi.
--Cham:
Springer
, c2016.
- Available Online
- View e-Book
- Location
- Online
This book focuses on the features of pelvic pain in the different cancer diseases, the pain assessment tools, as well as the pharmacological and non-pharmacological approaches. Pelvic cancer pain is a common and debilitating symptom, and pain control is a one among the main therapeutic goals throughout the duration of the disease. Because pelvic cancer pain due to primitive cancer, recurrence or metastasis is a complex clinical pathology, no single technique is often guaranteed to produce a com…
- Available Online
- View e-Book
- Author
- Cascella, Marco
- Other Authors
- Cuomo, Arturo
- Viscardi, Daniela
- Responsibility
- Marco Cascella, Arturo Cuomo, Daniela Viscardi
- Place of Publication
- Cham
- Publisher
- Springer
- Date of Publication
- c2016
- Physical Description
- 1 online resource (xxv, 164 p. : 7 illus., 6 illus. in color)
- ISBN
- 9783319335872
- 9783319335865 (print ed.)
- Subjects (MeSH)
- Pain Management - methods
- Pelvic Neoplasms - complications
- Pelvic Pain - diagnosis
- Pelvic Pain - therapy
- Abstract
- This book focuses on the features of pelvic pain in the different cancer diseases, the pain assessment tools, as well as the pharmacological and non-pharmacological approaches. Pelvic cancer pain is a common and debilitating symptom, and pain control is a one among the main therapeutic goals throughout the duration of the disease. Because pelvic cancer pain due to primitive cancer, recurrence or metastasis is a complex clinical pathology, no single technique is often guaranteed to produce a complete pain relief. Thus, there are many treatment options, but in most cases a correct approach to pain control should be provided by a multidisciplinary team under the responsibility of a pain specialist coordinating several professionals. This book will aid several figures of practitioners, like anesthesiologists, oncologists or surgeons, in making the correct decisions in individual patients affected by cancer pain due to pelvic diseases.
- Contents
- Part I. Features and Assessment -- 1. General Features of Pelvic Cancer Pain -- 2. Pelvic Pain in the Different Cancer Diseases -- 3. Pain Syndromes Associated with Cancer Therapy -- 4. Pain Assessment -- Part II. Treatments -- 5. Pharmacological Approaches -- 6. Palliative Radiotherapy -- 7. Central Neuraxial Blocks -- 8. Neurolytic Sympathetic Plexus Blocks -- 9. Minimally Invasive Palliative Treatments -- 10. Psychological, Behavioral and Rehabilitation Approaches to Cancer Pain Management -- 11. Pain Management Team and Palliative Care Setting -- 12. Conclusion.
- Format
- e-Book
- Location
- Online
edited by Daniela Prayer.
--Berlin, Heidelberg:
Springer-Verlag
, c2011.
- Available Online
- View e-Book
- Location
- Online
- Available Online
- View e-Book
- Author
- Prayer, Daniela
- Responsibility
- edited by Daniela Prayer
- Place of Publication
- Berlin, Heidelberg
- Publisher
- Springer-Verlag
- Date of Publication
- c2011
- Series
- Medical radiology. Diagnostic imaging
- Series Title
- Medical radiology (Series)
- ISBN
- 9783540732716
- Subjects (MeSH)
- Fetal Diseases - pathology
- Fetal Diseases - diagnostic imaging
- Fetus - diagnostic imaging
- Magnetic Resonance Imaging
- Radiography
- Subjects (LCSH)
- Obstetrics
- Radiology, Medical
- Diagnostic Imaging
- Format
- e-Book
- Location
- Online
Frozen Section Library. Pancreas
https://libcat.nshealth.ca/en/permalink/provcat30478
by Wendy L. Frankel, Daniela M. Proca.
--Boston, MA:
Springer
, c2011.
- Available Online
- View e-Book
- Location
- Online
- Available Online
- View e-Book
- Author
- Frankel, Wendy L
- Other Authors
- Proca, Daniela M
- Responsibility
- by Wendy L. Frankel, Daniela M. Proca
- Alternate Title
- Pancreas
- Place of Publication
- Boston, MA
- Publisher
- Springer
- Date of Publication
- c2011
- Series Vol.
- 8
- Series Title
- Frozen section library series
- ISBN
- 9781441977908
- Subjects (MeSH)
- Pancreas - pathology - Atlases
- Pancreatic Diseases - diagnosis - Atlases
- Pancreatic Diseases - pathology - Atlases
- Frozen Sections - Atlases
- Subjects (LCSH)
- Gastroenterology
- Pathology
- Format
- e-Book
- Location
- Online
Glucose Sensor Use in Children and Adolescents : A Practical Guide
https://libcat.nshealth.ca/en/permalink/provcat45548
Valentino Cherubini, Daniela Elleri, Stefano Zucchini, editors.
--Cham:
Springer
, c2020.
- Available Online
- View e-Book
- Location
- Online
This practical book focuses on the use of glucose sensors in children with type 1 diabetes. It is an evidence-based, simple, illustrated tool written by expert physicians in the field, experienced with patients living in Italy and in the UK. The introductory chapters offer a quick and well-documented update on technology use in the child with diabetes, while the chapter on clinical studies provides a comprehensive overview of the scientific basis and benefits on glucose sensor use. The practica…
- Available Online
- View e-Book
- Other Authors
- Cherubini, Valentino
- Elleri, Daniela
- Zucchini, Stefano
- Responsibility
- Valentino Cherubini, Daniela Elleri, Stefano Zucchini, editors
- Place of Publication
- Cham
- Publisher
- Springer
- Date of Publication
- c2020
- Physical Description
- 1 online resource (viii, 97 p.) : 30 illus., 29 illus. in color
- ISBN
- 9783030428068
- 9783030428051 (Print ed.)
- 9783030428075 (Print ed.)
- 9783030428082 (Print ed.)
- Subjects (MeSH)
- Adolescent
- Child
- Blood Glucose Self-Monitoring
- Monitoring, Ambulatory
- Abstract
- This practical book focuses on the use of glucose sensors in children with type 1 diabetes. It is an evidence-based, simple, illustrated tool written by expert physicians in the field, experienced with patients living in Italy and in the UK. The introductory chapters offer a quick and well-documented update on technology use in the child with diabetes, while the chapter on clinical studies provides a comprehensive overview of the scientific basis and benefits on glucose sensor use. The practical use of sensors in all age groups, including toddlers, and any related psychological issues are also discussed. This volume allows health care professionals, pediatric trainees and medical students caring for children with type 1 diabetes to increase their understanding of sensor use, making this technology easier and more reliable to use.
- Contents
- 1. Introduction on Use of Technology in Pediatric Type 1 Diabetes -- 2. The Technology of Glucose Sensors -- 3. Different Types of Continuous Glucose Monitoring Systems on the Market -- 4. Clinical Studies on Efficacy of Continuous Glucose Monitoring -- 5. Sensor Use in Toddlers and Pre-school Children -- 6. Continuous Glucose Monitoring (CGM) Use in Adolescents -- 7. Unexpected Highs and Lows -- 8. How to Insert and Wear CGM -- 9. Pitfalls in the Use of Continuous Glucose Monitoring -- 10. Psychological Issues -- 11. Conclusions.
- Format
- e-Book
- Location
- Online
Neurodegenerative Diseases : Clinical Aspects, Molecular Genetics and Biomarkers
https://libcat.nshealth.ca/en/permalink/provcat43105
Daniela Galimberti, Elio Scarpini, editors.
(Second edition)
--Cham:
Springer
, c2018.
- Available Online
- View e-Book
- Location
- Online
This book gives an overview of the current knowledge on the most common neurodegenerative diseases, including Alzheimer's disease, frontotemporal lobar degeneration, Lewy body dementia,Parkinson's disease, amyotrophic lateral sclerosis, and additional less common neurodegenerative diseases. Both clinical and basic aspects of each disease are treated, including novel diagnostic criteria, old and new treatments, basic discoveries (genetics, epigenetics and molecular biology), and translation of b…
- Available Online
- View e-Book
- Other Authors
- Galimberti, Daniela
- Scarpini, Elio
- Responsibility
- Daniela Galimberti, Elio Scarpini, editors
- Edition
- Second edition
- Place of Publication
- Cham
- Publisher
- Springer
- Date of Publication
- c2018
- Physical Description
- 1 online resource (x, 407 p.) : 23 illus., 20 illus. in color
- ISBN
- 9783319729381
- 9783319729374 (print ed.)
- 9783319729398 (print ed.)
- Subjects (MeSH)
- Nerve Degeneration
- Nervous System Physiological Phenomena
- Nervous System - physiopathology
- Neurodegenerative Diseases
- Abstract
- This book gives an overview of the current knowledge on the most common neurodegenerative diseases, including Alzheimer's disease, frontotemporal lobar degeneration, Lewy body dementia,Parkinson's disease, amyotrophic lateral sclerosis, and additional less common neurodegenerative diseases. Both clinical and basic aspects of each disease are treated, including novel diagnostic criteria, old and new treatments, basic discoveries (genetics, epigenetics and molecular biology), and translation of basic research into biomarkers for early diagnosis, particularly to identify peripheral biomarkers. In addition, emerging data indicate that neurodegeneration seems to also be present in classically non-degenerative disorders. Therefore, a chapter about overlapping mechanisms between dementias and psychiatric disorders is included, as well as a description of the role of neurodegeneration in multiple sclerosis. Neurodegenerative Diseases is aimed at clinicians, particularly those working in academic hospitals. This multidisciplinary book will also be of interest to basic researchers in medical fields.
- Contents
- 1. Genetics and epigenetics in the neurodegenerative disorders of the central nervous system -- 2. Diagnosis of Alzheimer's disease typical and atypical forms -- 3. Genetic complexity of early-onset Alzheimer's disease -- 4. Genetic risk factors for complex forms of Alzheimer's disease -- 5. Role of cerebrovascular disease in cognition -- 6. Risk factors and prevention in Alzheimer's disease and dementia -- 7. Diagnosis of frontotemporal dementia -- 8. Autosomal dominant frontotemporal lobar degeneration: from genotype to phenotype -- 9. Genetic risk factors for sporadic frontotemporal dementia -- 10. Alzheimer's disease and frontotemporal lobar degeneration: mouse models -- 11. Fluid biomarkers in Alzheimer's disease and frontotemporal dementia -- 12. Biomarkers for Alzheimer's disease and frontotemporal lobar degeneration: imaging -- 13. Genotypic and phenotypic heterogeneity in Amyotrophic lateral sclerosis -- 14. Lewy body dementia -- 15. Rare dementias -- 16. Neurodevelopmental and neurodegenerative alterations in the pathophysiology of schizophrenia: focus on neuro-immuno-inflammation -- 17. Parkinson's disease: contemporary concepts and clinical management -- 18. Neurodegeneration and multiple sclerosis.
- Format
- e-Book
- Location
- Online
Neurodegenerative diseases : clinical aspects, molecular genetics and biomarkers
https://libcat.nshealth.ca/en/permalink/provcat33732
Daniela Galimberti, Elio Scarpini, editors.
--London:
Springer
, c2014.
- Available Online
- View e-Book
- Location
- Online
This book gives an overview of the current knowledge on the most common neurodegenerative diseases, including Alzheimer's disease, frontotemporal lobar degeneration, amyotrophic lateral sclerosis, and additional neurodegenerative diseases. Different aspects of each disease are reviewed, including clinical issues, treatments, basic discoveries (genetics and molecular biology), and translation of basic research into biomarkers for early diagnosis. In addition, emerging data indicate that neurodeg…
- Available Online
- View e-Book
- Other Authors
- Galimberti, Daniela
- Scarpini, E
- Responsibility
- Daniela Galimberti, Elio Scarpini, editors
- Place of Publication
- London
- Publisher
- Springer
- Date of Publication
- c2014
- Physical Description
- 1 online resource (xix, 253 pages)
- ISBN
- 9781447163800 (electronic bk.)
- 9781447163794
- Subjects (MeSH)
- Alzheimer Disease
- Neurodegenerative Diseases
- Biological Markers
- Subjects (LCSH)
- Nervous system - Degeneration
- Neurology
- Neurosciences
- Abstract
- This book gives an overview of the current knowledge on the most common neurodegenerative diseases, including Alzheimer's disease, frontotemporal lobar degeneration, amyotrophic lateral sclerosis, and additional neurodegenerative diseases. Different aspects of each disease are reviewed, including clinical issues, treatments, basic discoveries (genetics and molecular biology), and translation of basic research into biomarkers for early diagnosis. In addition, emerging data indicate that neurodegeneration seems to also be present in classically non-degenerative disorders. Therefore, a chapter about overlapping mechanisms between dementias and psychiatric disorders is included, as well as a description of the role of neurodegeneration in multiple sclerosis. Neurodegenerative Diseases is aimed at clinicians, particularly those working in academic hospitals. This multidisciplinary book will also be of interest to basic researchers in medical fields.
- Contents
- Genetics and Epigenetics: Basic Concepts -- Alzheimer's Disease: Clinical Aspects and Treatments -- Autosomal Dominant Alzheimer's Disease: Underlying Causes -- Genetic Risk Factors for Alzheimer's Disease -- The Role of Cerebrovascular Disease in Cognitive Decline -- Nongenetic Risk Factors for Alzheimer's Disease -- Nongenetic Risk Factors for Alzheimer's Disease -- Frontotemporal Lobar Degeneration: Genetics and Clinical Phenotypes -- Alzheimer's Disease and Frontotemporal Lobar Degeneration: Mouse Models -- Cerebrospinal Fluid Biomarkers in Alzheimer's Disease and Frontotemporal Dementia -- Biomarkers for Alzheimer's Disease and Frontotemporal Lobar Degeneration: Imaging -- Amyotrophic Lateral Sclerosis: Genotypes and Phenotypes -- Uncommon Dementias -- Neurodevelopment Alterations, Neurodegeneration, and Immunoinflammatory Patterns in the Pathophysiology of Schizophrenia -- Neurodegeneration and Multiple Sclerosis.
- Format
- e-Book
- Location
- Online
Ocular disease : mechanisms and management
https://libcat.nshealth.ca/en/permalink/provcat31547
[edited by] Leonard A. Levin, Daniel M. Albert.
--[Philadelphia]:
Saunders/Elsevier
, 2010.
- Available Online
- View e-Book
- Access
- Registration required for PDF access.
- Location
- Online
Ocular Disease-a newly introduced companion volume to the classic Adlers Physiology of the Eye-correlates basic science and clinical management to describe the how and why of eye disease processes and the related best management protocols. Editors Leonard A. Levin and Daniel M. Albert-two of the world's leading ophthalmic clinician-scientists-have recruited as contributors the most expert and experienced authorities available in each of the major areas of ophthalmic disease specific to ophthalm…
- Available Online
- View e-Book
- Other Authors
- Levin, Leonard A
- Albert, Daniel M
- Responsibility
- [edited by] Leonard A. Levin, Daniel M. Albert
- Place of Publication
- [Philadelphia]
- Publisher
- Saunders/Elsevier
- Date of Publication
- 2010
- Physical Description
- 1 online resource (xv, 687 p.)
- ISBN
- 9780702029837
- Subjects (MeSH)
- Eye Diseases
- Eye - physiopathology
- Subjects (LCSH)
- Ophthalmology
- Eye - Diseases
- Eye - Diseases - Treatment
- Eye Diseases
- Eye - physiopathology
- Ophtalmologie
- Œil - Maladies
- Œil - Maladies - Traitement
- Notes
- "Expert consult"--Cover
- Abstract
- Ocular Disease-a newly introduced companion volume to the classic Adlers Physiology of the Eye-correlates basic science and clinical management to describe the how and why of eye disease processes and the related best management protocols. Editors Leonard A. Levin and Daniel M. Albert-two of the world's leading ophthalmic clinician-scientists-have recruited as contributors the most expert and experienced authorities available in each of the major areas of ophthalmic disease specific to ophthalmology: retina, cornea, cataract, glaucoma, uveitis, and more. The concise chapter structure features liberal use of color-with 330 full-color line artworks, call-out boxes, summaries, and schematics for easy navigation and understanding. In print and online at expertconsult.com, this comprehensive resource provides you with a better and more practical understanding of the science behind eye disease and its relation to treatment. Includes access to the fully searchable text online at expertconsult.com, along with images and references. Covers all areas of disease in ophthalmology including retina, cornea, cataract, glaucoma, and uveitis for the comprehensive information you need for managing clinical cases. Presents a unique and pragmatic blend of necessary basic science and clinical application to serve as a clinical guide to understanding the cause and rational management of ocular disease
- Contents
- Loss of corneal transparency / Russell L McCally -- Abnormalities of corneal wound healing / Audrey M Bernstein -- Wound healing after laser in situ keratomileusis and photorefractive keratectomy / Fabricio Witzel de Medeiros and Steven E Wilson -- Genetics and mechanisms of hereditary corneal dystrophies / John D Gottsch -- Fuchs' endothelial corneal dystrophy / Vinay Gutti, David S Bardenstein, Sudha Iyengar, and Jonathan H Lass -- Keratoconus / M Cristina Kenney and Ronald N Gaster -- Infectious keratitis / Michael S Gilmore, Susan R Heimer, and Ai Yamada -- Corneal graft rejection / Daniel R Saban, Mohammad H Dastjerdi, and Reza Dana -- Corneal edema / Daniel G Dawson and Henry F Edelhauser -- Corneal angiogenesis and lymphangiogenesis / Chih-Wei Wu, David Ellenberg, and Jin-Hong Chang -- Ocular surface restoration / Julie T Daniels, Genevieve A Secker, and Alex J Shortt -- Herpetic keratitis / Pranita P Sarangi and Barry T Rouse -- Ocular allergy / Neal P Barney, Ellen B Cook, James L Stahl, and Frank M Graziano -- The lacrimal gland and dry-eye disease / Darlene A Dartt -- Immune mechanisms of dry-eye disease / Austin K Mircheff and Joel E Schechter -- Disruption of tear film and blink dynamics / Jianhua Wang and Anuj Chauhan -- Abnormalities of eyelid and tear film lipid / Gary N Foulks and Douglas Borchman -- Dry eye: abnormalities of tear film mucins / Ann-Christin Albertsmeyer and Ilene K Gipson -- Steroid-induced glaucoma / Abbot F Clark, Xinyu Zhang, and Thomas Yorio -- Biomechanical changes of the optic disc / Ian A Sigal, Michael D Roberts, Michael JA Girard, Claude F Burgoyne, and J Crawford Downs -- Pigmentary dispersion syndrome and glaucoma / Michael G Anderson -- Abnormal trabecular meshwork outflow / Paul A Knepper and Beatrice YJT Yue -- Pressure-induced optic nerve damage / James C Tsai -- Exfoliation (pseudoexfoliation) syndrome / Robert Ritch and Ursula Schultzer-Schrehardt -- Angle closure glaucoma / Shamira Perera, Nishani Amerasinghe, and Tin Aung -- Central nervous system changes in glaucoma / Yeni N Yücel and Neeru Gupta -- Retinal ganglion cell death in glaucoma / Heather R Pelzel and Robert W Nickells -- Wound-healing responses to glaucoma surgery / Stelios Georgoulas, Annegret Dahlmann-Noor, Stephen Brocchini, and Peng Tee Khaw -- Blood flowchanges in glaucoma / Leopold Schmetterer and Mark Lesk -- Biochemical mechanisms of age-related cataract / David C Beebe, Ying-Bo Shui, and Nancy M Holekamp -- Posterior capsule opacification / Judith West-Mays and Heather Sheardown -- Diabetes-associated cataracts / Peter F Kador -- Steroid-induced cataract / Abbas Samadi -- Presbyopia / Jane F Koretz -- Restoration of accommodation / Stephen D McLeod and Michelle Trager Cabrera -- Intraoperative floppy iris syndrome / Amy Lin and Roger F Steinert -- Optic neuritis / John R Guy and Xiaoping Qi -- Abnormal ocular motor control / James A Sharpe and Arun Sundaram -- Idiopathic intracranial hypertension (idiopathic pseudotumor cerebri) / Deborah M Grzybowski and Martin Lubow -- Giant cell arteritis / Lynn K Gordon -- Ischemic optic neuropathy / Helen Danesh-Meyer -- Optic nerve axonal injury / Daniela Toffoli and Leonard A Levin -- Leber's hereditary optic neuropathy / Alfredo Sadun and Alice Kim -- Optic atrophy / Nathan T Tagg and Randy H Kardon -- Nystagmus / Frank Proudlock and Irene Gottlob -- Toxic optic nerve neuropathies / FT "Fritz" Fraunfelder and FW "Rick" Fraunfelder -- Uveal melanoma / Zelia MS Correa and J William Harbour -- Genetics of hereditary retinoblastoma / Alejandra G de Alba Campomanes and Joan M O'Brien -- Molecular basis of low-penetrance retinoblastoma / Katie Matatall and J William Harbour -- Vasculogenic mimicry / Robert Folberg and Andrew J Maniotis -- Treatment of choroidal melanoma / Aimee V Chappelow and Andrew P Schachat -- Sebaceous cell carcinoma / Alon Kahana, Jonathan T Pribila, Christine C Nelson, and Victor M Elner -- Neurofibromatosis / Robert Listernick and David H Gutmann -- Phthisis bulbi / Ingo Schmack, Hans E Volcker, and Hans E Grossniklaus -- Myopia / Terri L Young -- Pathogenesis of Graves' ophthalmopathy / A Reagan Schiefer and Rebecca S Bahn -- Duane syndrome / Joseph L Demer -- Amblyopia / Robert F Hess and Nigel Daw -- Strabismus / Christopher S von Bartheld, Scott A Croes, and L Alan Johnson -- Albinism / Gerald F Cox and Anne B Fulton -- Aniridia / Elias I Traboulsi -- Color vision defects / Maureen Neitz and Jay Neitz -- Acute retinal vascular occlusive disorders / Sohan Singh Hayreh -- Retinal photic injury: laboratory and clinical findings / Daniel Organisciak and Marco Zarbin -- Vascular damage in diabetic retinopathy / Timothy S Kern and Suber Huang -- Neovascularization in diabetic retinopathy / Corey B Westerfeld and Joan W Miller -- Diabetic macular edema / Pascale Massin, Michel Paques, and Jean-Antoine Pournaras --Dry age-related macular degeneration and age-related macular degeneration pathogenesis / Marco Zarbin and Janet S Sunness -- Neovascular age-related macular degeneration / David E Lederer, Scott W Cousins, and Karl G Csaky -- Inhibition of / Anthony P Adamis and Adrienne Berman -- Retinal detachment / Steven K Fisher and Geoffrey P Lewis -- Retinopathy of prematurity / Mary Elizabeth Hartnett and Cynthia A Toth -- Retinal energy metabolism / Robert A Linsenmeier -- Retinitis pigmentosa and related disorders / Eric A Pierce -- Visual prostheses and other assistive devices / Muhammad Ali Memon and Joseph F Rizzo III -- Paraneoplastic retinal degeneration / Grazyna Adamus -- Cellular repopulation of the retina / Budd AL Tucker, Michael J Young, and Henry J Klassen -- Proliferative vitreoretinopathy / Clyde Guidry -- Immunologic mechanisms of uveitis / Steven Yeh, Zhuqing Li, and Robert B Nussenblatt -- Herpesvirus retinitis / Sally S Atherton and Mei Zheng -- Sympathetic ophthalmia / Mirunalini Kumaradas and Narsing A Rao -- Scleritis / Srilakshmi M Sharma and James T Rosenbaum -- Infectious uveitis / Pooja Bhat, Allen Tony Jackson, and C Stephen Foster -- Ocular sarcoidosis / Russell N Van Gelder and Suzanne M Dintzis
- Access
- Registration required for PDF access.
- Format
- e-Book
- Location
- Online
Pediatric Cancer in Africa : A Case-Based Guide to Diagnosis and Management
https://libcat.nshealth.ca/en/permalink/provcat41261
Daniela Cristina Stefan, Mhamed Harif.
--Cham:
Springer
, 2017.
- Available Online
- View e-Book
- Location
- Online
This text is the only book of its kind to provide specific guidance applicable to limited resource settings and builds up from the foundation of general practitioner or general pediatrician competence. Written and edited by leaders in the field, this manual educates physicians on the essential components of the discipline, filtered through the experience of specialists from developing countries, with immediate applicability in the specific healthcare environment in these countries. Typically, m…
- Available Online
- View e-Book
- Author
- Stefan, Daniela Cristina
- Other Authors
- Harif, Mhamed
- Responsibility
- Daniela Cristina Stefan, Mhamed Harif
- Place of Publication
- Cham
- Publisher
- Springer
- Date of Publication
- 2017
- Physical Description
- 1 online resource (xvii, 408 pages) : 129 illus., 82 illus. in color
- ISBN
- 9783319179360
- 9783319179353 (print ed.)
- Subjects (MeSH)
- Africa - Epidemiology
- Developing Countries
- Neoplasms - diagnosis
- Neoplasms - epidemiology
- Neoplasms - therapy
- Abstract
- This text is the only book of its kind to provide specific guidance applicable to limited resource settings and builds up from the foundation of general practitioner or general pediatrician competence. Written and edited by leaders in the field, this manual educates physicians on the essential components of the discipline, filtered through the experience of specialists from developing countries, with immediate applicability in the specific healthcare environment in these countries. Typically, manuals of pediatric hematology-oncology are written by specialists from high-income countries, and usually target an audience with a sub-specialist level of training, often assisted by cutting-edge diagnostic and treatment facilities. However, approximately 80% of new cases of cancer in children appear in mid- and low-income countries. Almost invariably, general practitioners or general pediatricians without special training in oncology will look after children with malignancies who enter the health care system in these countries. The diagnostic facilities are usually limited, as are the treatment options. The survival figures in these conditions are somewhere below 20%, while in high-income countries they are in the range of 80% for many childhood cancers. This book includes simplified therapy protocols, pain therapy and palliation, as well as ward procedures such as bone marrow aspiration/biopsies, intravenous therapy and chemotherapy drugs mixing. It provides an overview of pediatric cancer epidemiology, cancer registration and organizing support networks and features the management of cancers with associated pathology like AIDS, malnutrition, malaria and tuberculosis.
- Contents
- 1. Epidemiology/etiology of childhood cancer -- 2. Early Warning Signs and Diagnostic Approach in Childhood Cancer -- 3. Cancer Registries and the Value of a Dedicated Pediatric Registry in Africa -- 4. Organization of Care for Children with Cancer in Africa -- 5. Hematological and Oncological Emergencies -- 6. Solid Tumors - Osteosarcoma -- 7. Ewing Sarcoma --8. Nephroblastoma (Wilms tumor) -- 9. Hepatoblastoma -- 10. Retinoblastoma -- 11. Neuroblastoma -- 12. Germ Cell Tumors -- 13. Hodgkin Lymphoma -- 14. Non-Hodgkin Lymphoma -- 15.Acute Leukemia -- 16.Chronic Leukemias in Children -- 17. Tumors of the Central Nervous System -- 18. Rare Childhood Cancers -- 19.HIV-Related Malignancies -- 20. Characteristics of Cancers in the Neonatal Period -- 21. Cancers in Adolescence -- 22. Cancer Chemotherapy -- 23. Febrile Neutropenia -- 24. Blood Transfusion in Pediatric Oncology -- 25. Nutrition for Children with Cancer in Africa -- 26. Pain in Pediatric Oncology -- 27. Nursing Care Principles in Pediatric Oncology -- 28. Chemotherapy Induced Nausea and Vomiting -- 29. Patient Support Groups -- 30. Research and Ethics in Pediatric Oncology -- 31. Health Economics -- 32. Developing Support Network in Africa.
- Format
- e-Book
- Location
- Online
Pediatric hematology-oncology in countries with limited resources : a practical manual
https://libcat.nshealth.ca/en/permalink/provcat33686
Daniela Cristina Stefan, Carlos Rodriguez-Galindo, editors.
--New York:
Springer
, c2014.
- Available Online
- View e-Book
- Location
- Online
Typically, manuals of pediatric hematology-oncology are written by specialists from high-income countries, and usually target an audience with a sub-specialist level of training, often assisted by cutting-edge diagnostic and treatment facilities. However, approximately 80% of new cases of cancer in children appear in mid- and low-income countries. Almost invariably, general practitioners or general pediatricians without special training in oncology will look after children with malignancies who…
- Available Online
- View e-Book
- Other Authors
- Stefan, Daniela Cristina
- Rodriguez-Galindo, Carlos
- Responsibility
- Daniela Cristina Stefan, Carlos Rodriguez-Galindo, editors
- Place of Publication
- New York
- Publisher
- Springer
- Date of Publication
- c2014
- Physical Description
- 1 online resource (xvi, 415 pages)
- ISBN
- 9781461438915 (electronic bk.)
- 9781461438908
- Subjects (MeSH)
- Developing Countries
- Health Care Rationing
- Health Resources
- Neoplasms
- Resource Allocation
- Subjects (LCSH)
- Tumors in children
- Pediatric hematology
- Hematology
- Infant
- Child
- Adolescent
- Public Health - economics
- Oncology
- Pediatrics
- Abstract
- Typically, manuals of pediatric hematology-oncology are written by specialists from high-income countries, and usually target an audience with a sub-specialist level of training, often assisted by cutting-edge diagnostic and treatment facilities. However, approximately 80% of new cases of cancer in children appear in mid- and low-income countries. Almost invariably, general practitioners or general pediatricians without special training in oncology will look after children with malignancies who enter the health care system in these countries. The diagnostic facilities are usually limited, as are the treatment options. The survival figures in these conditions are somewhere below 20%, while in high-income countries they are in the range of 80% for many childhood cancers. Pediatric Hematology-Oncology in Countries with Limited Resources is the only book of its kind to provide specific guidance applicable to limited resource settings and builds up from the foundation of general practitioner or general pediatrician competence. Written and edited by leaders in the field, this manual educates physicians on the essential components of the discipline, filtered through the experience of specialists from developing countries, with immediate applicability in the specific healthcare environment in these countries.
- Contents
- Childhood Cancer in Low-Income and Middle-Income Countries in the Twenty-First Century -- Cancer Registries and the Descriptive Epidemiology of Pediatric Cancer in Low -- and Middle-Income Countries -- The Role of International Organizations on Collaborationfor Global Pediatric Cancer Control -- The Role of Twinning Programs and Telemedicine in Pediatric Oncology -- Pediatric Cancer Units and Optimization of Resources -- Early Warning Signs of Cancer in Children/Models for Early Diagnosis -- Care and Prevention of Infection -- Nutritional Assessment and Intervention -- Oncologic Emergencies -- Essential Medicines and Pharmacy Services -- Palliative and Supportive Care -- Psycho-Social Aspects/Parent Support Groups -- Nursing Care of Children with Cancer -- Paediatric Radiotherapy -- Procedures in Pediatric Oncology: Practical Guidelines -- Acute Lymphoblastic Leukemia -- Acute Myeloid Leukemia -- Hodgkin Lymphoma -- Non-Hodgkin Lymphoma -- Retinoblastoma -- Soft Tissue Sarcomas -- Bone Tumors -- Neuroblastoma -- Nephroblastoma -- Paediatric Neuro-Oncology -- HIV and Malignancy in Children -- Hematopoietic Stem Cell Transplant.
- Format
- e-Book
- Location
- Online
Sedentary Behaviour Epidemiology
https://libcat.nshealth.ca/en/permalink/provcat43298
Michael F. Leitzmann, Carmen Jochem, Daniela Schmid, editors.
--Cham:
Springer
, c2018.
- Available Online
- View e-Book
- Location
- Online
This book addresses the origins, determinants and magnitude of the global problem of sedentary behaviour, along with concise yet in-depth solutions for tackling it. As a consequence of major technological advances in modern society, many people find themselves in environments characterized by prolonged sedentary behaviour. Although inadequate exercise has long been known to cause adverse health consequences, sedentary behaviour has recently emerged as a risk factor for the development of numero…
- Available Online
- View e-Book
- Other Authors
- Leitzmann, Michael F.
- Jochem, Carmen
- Schmid, Daniela
- Responsibility
- Michael F. Leitzmann, Carmen Jochem, Daniela Schmid, editors
- Place of Publication
- Cham
- Publisher
- Springer
- Date of Publication
- c2018
- Physical Description
- 1 online resource (xv, 650 p.) : 53 illus., 31 illus. in color
- Series Title
- Springer series on epidemiology and public health
- ISBN
- 9783319615523
- 9783319615509 (print ed.)
- 9783319615516 (print ed.)
- 9783319871097 (print ed.)
- ISSN
- 1869-7933
- Subjects (MeSH)
- Health Promotion
- Health Risk Behaviors
- Sedentary Behavior
- Specialty
- Public Health
- Abstract
- This book addresses the origins, determinants and magnitude of the global problem of sedentary behaviour, along with concise yet in-depth solutions for tackling it. As a consequence of major technological advances in modern society, many people find themselves in environments characterized by prolonged sedentary behaviour. Although inadequate exercise has long been known to cause adverse health consequences, sedentary behaviour has recently emerged as a risk factor for the development of numerous chronic diseases and health conditions. Building on the contributions of leading experts in the field, this book presents current knowledge about sedentary behaviour, its medical and public health significance, its correlates and determinants, measurement techniques, and recommendations for addressing this behaviour at the individual, community, environmental, and policy level. Applying a cross-disciplinary methodology, the book avoids considering physical activity and sedentary behavior as a single continuum, which potentially hampers progress in confronting widespread levels of sedentariness. Rather, the book helps readers better understand how sedentary and physically active behavior co-occur and how the two behaviours have distinct contributing factors. Building on the contributions of distinguished international experts in the field, this thorough resource is a valuable asset and challenges professionals, researchers, students, and practitioners alike to adopt new strategies and expand their reach.
- Contents
- Introduction to Sedentary Behaviour Epidemiology -- Measurement of Sedentary Behaviour in Population Studies -- Analysis and Interpretation of Sedentary Behaviour Data -- The Descriptive Epidemiology of Sedentary Behaviour -- Physiologic Responses to Sedentary Behaviour -- Sedentary Behaviour and Adiposity -- Non-Exercise Activity Thermogenesis (NEAT) and Adiposity -- Sedentary Behaviour, Diabetes, and the Metabolic Syndrome -- Sedentary Behaviour and Cardiovascular Disease -- Sedentary Behaviour and Cancer -- Sedentary Behaviour and Depression -- Sedentary Behaviour and Psychosocial Health across the Life Course -- Sedentary Behaviour and Aging -- Sedentary Behaviour and Mortality -- Models for Understanding Sedentary Behaviour -- Sedentary Behaviour at the Individual Level: Correlates, Theories, and Interventions -- Specific Interventions Targeting Sedentary Behaviour in Children and Adolescents -- Workplace Programs Aimed at Limiting Occupational Sitting -- Approaches to Decrease Sedentary Behaviour Among the Elderly -- Interventions Directed at Reducing Sedentary Behaviour in Persons with Pre-existing Disease or Disability -- Specific Approaches to Reduce Sedentary Behaviour in Overweight and Obese People -- Programs Targeting Sedentary Behaviour Among Ethnic Minorities and Immigrants -- Sedentary Behaviour at the Community Level: Correlates, Theories, and Interventions -- Sedentary Behaviour and the Social and Physical Environment -- Targeting Sedentary Behaviour at the Policy Level -- Dynamics of Sedentary Behaviours and Systems-Based Approach: Future Challenges and Opportunities in the Life Course Epidemiology of Sedentary Behaviours -- Genetics of Sedentariness -- Limitations in Sedentary Behaviour Research and Future Research Needs.
- Format
- e-Book
- Location
- Online
Spinal imaging
https://libcat.nshealth.ca/en/permalink/provcat33093
[edited by] Herwig Imhof ; with contributions by Benjamin Halpern ... [et al. ; translator: John Grossman ; illustrator, Emil Wolfgang Hanns].
--Stuttgart:
Thieme
, c2008.
- Available Online
- View e-Book
- Location
- Online
Dx-direct is a series of eleven Thieme books covering the main subspecialties in radiology. It includes all the cases you are most likely to see in your typical working day as a radiologist. For each condition or disease you will find the information you need-- with just the right level of detail. Dx-direct gets to the point: definitions, epidemiology, etiology, and imaging signs; typical presentation, treatment options, course and prognosis; differential diagnosis, tips and pitfalls, and key r…
- Available Online
- View e-Book
- Other Authors
- Imhof, H
- Halpern, Benjamin
- Responsibility
- [edited by] Herwig Imhof ; with contributions by Benjamin Halpern ... [et al. ; translator: John Grossman ; illustrator, Emil Wolfgang Hanns]
- Alternate Title
- Dx-direct. Spinal imaging
- Direct diagnosis in radiology - spinal imaging
- Place of Publication
- Stuttgart
- Publisher
- Thieme
- Date of Publication
- c2008
- Physical Description
- 1 online resource (ix, 302 p.)
- Series
- Dx-direct
- Series Title
- Direct diagnosis in radiology
- ISBN
- 9781588905604
- 9783131627810 (eISBN)
- Subjects (MeSH)
- Spinal Diseases - diagnosis - Handbooks
- Spinal Cord Diseases - diagnosis - Handbooks
- Diagnosis, Differential - Handbooks
- Diagnostic Imaging - Handbooks
- Subjects (LCSH)
- Spinal Diseases - diagnosis - Handbooks
- Diagnostic Imaging - methods - Handbooks
- Spinal Cord Diseases - diagnosis - Handbooks
- Spinal cord - Diseases - Diagnosis
- Spine - Imaging
- Spinal cord - Imaging
- Spine - Diseases - Diagnosis
- Specialty
- Diagnostic Imaging
- Abstract
- Dx-direct is a series of eleven Thieme books covering the main subspecialties in radiology. It includes all the cases you are most likely to see in your typical working day as a radiologist. For each condition or disease you will find the information you need-- with just the right level of detail. Dx-direct gets to the point: definitions, epidemiology, etiology, and imaging signs; typical presentation, treatment options, course and prognosis; differential diagnosis, tips and pitfalls, and key references ... all combined with high-quality diagnostic images. Whether you are a resident or a trainee, preparing for board examinations or just looking for a superbly organized reference: Dx-direct is the high-yield choice for you! The series covers the full spectrum of radiology subspecialties including: brain, gastrointestinal, cardiac, breast, urogenital, spinal, head and neck, musculoskeletal, pediatric, thoracic, vascular.
- Contents
- Congenital malformations / Christina Mueller-Mang ... [et al.] -- Trauma / Christina Mueller-Mang ... [et al.] -- Degenerative disorders / Iris-Melanie Noebauer-Huhmann, Michael Matzner ... [et al.] -- Inflammatory disorders / Christina Mueller-Mang ... [et al.] -- Tumors / Andreas M. Herneth ... [et al.] -- Vascular disorders / Christina Mueller-Mang, Daniela Prayer -- Postoperative disorders / Andreas M. Herneth, Michael Matzner, Herwig Imhof -- Metabolic disorders / Andreas M. Herneth, Herwig Imhof.
- Format
- e-Book
- Publication Type
- Handbook
- Location
- Online
Tumors of the Central Nervous System. Vol. 8, Astrocytoma, Medulloblastoma, Retinoblastoma, Chordoma, Craniopharyngioma, Oligodendroglioma, and Ependymoma
https://libcat.nshealth.ca/en/permalink/provcat31282
edited by M.A. Hayat.
--Dordrecht:
Springer
, c2012.
- Available Online
- View e-Book
- Location
- Online
With tens of thousands of new CNS tumor cases each year in the US alone, this series of publications is a valuable aid to the diagnosis and treatment of these problematic neoplasms. Now, the eighth in the set returns to the topic of brain tumors, dealing with seven distinct types: astrocytoma, medulloblastoma, retinoblastoma, chordoma, craniopharyngioma, oligodendroglioma, and ependymoma. After updating the classification of medulloblastoma the volume provides an overview of ependymoma as well …
- Available Online
- View e-Book
- Other Authors
- Hayat, M.A
- Responsibility
- edited by M.A. Hayat
- Alternate Title
- Astrocytoma, Medulloblastoma, Retinoblastoma, Chordoma, Craniopharyngioma, Oligodendroglioma, and Ependymoma
- Place of Publication
- Dordrecht
- Publisher
- Springer
- Date of Publication
- c2012
- Physical Description
- 1 online resource (xxxvii, 338 p. : 50 ill., 38 ill. in color)
- Series Vol.
- v. 8
- Series Title
- Tumors of the central nervous system
- ISBN
- 9789400742130
- Subjects (MeSH)
- Brain neoplasms
- Central Nervous System Neoplasms
- Neuroectodermal Tumors
- Subjects (LCSH)
- Oncology
- Neurosciences
- Abstract
- With tens of thousands of new CNS tumor cases each year in the US alone, this series of publications is a valuable aid to the diagnosis and treatment of these problematic neoplasms. Now, the eighth in the set returns to the topic of brain tumors, dealing with seven distinct types: astrocytoma, medulloblastoma, retinoblastoma, chordoma, craniopharyngioma, oligodendroglioma, and ependymoma. After updating the classification of medulloblastoma the volume provides an overview of ependymoma as well as describing the delineation of prognosis based on the genetic aberrations of the latter patients. The material offers key insights into the molecular pathways involved in tumor biology, such as the role of E-cadherin gene instability, carbonic anhydrase II, urokinase plasminogen activator, and Wnt signaling in meningioma. Contributors explain the genetic and clinical features associated with recurring meningioma, including the role played by erythropoietin receptor, and examine the way in which OTX2 transcription factor functions as an oncogene in medulloblastoma. With much more besides, including discussion of the molecular mechanisms that result in resistance to chemotherapy in medulloblastoma, this volume and its companions have a positive role to play in inspiring a new generation of researchers to design new drugs that are better targeted'and thus more effective.
- Contents
- [Machine generated contents note] Pt. I Astrocytoma -- 1. Astrocytoma Cell Line: Role of Brain Natriuretic Peptide / Ken Okumura -- 2. Malignant Brain Astrocytomas: Extent of Resection Affects Survival / Matthew J. McGirt -- Pt. II Medulloblastoma -- 3. Medulloblastoma: Classification (A Review) / Antonio Giordano -- 4. Medulloblastomas: Clinically Important MicroRNA Genes / Deepak Kamnasaran -- 5. Medulloblastoma: Role of OTX2 Transcription Factors / D. Cory Adamson -- 6. Molecular Mechanisms of Chemoresistance in Medulloblastoma / Daniel Meley -- 7. Extraneural Metastasis in Medulloblastoma / Arnold C. Paulino -- 8. Medulloblastoma: Therapy with Bortezomib/Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand / Heidrun Holland -- 9. Standard-Risk Medulloblastoma: Hyperfractionated Radiotherapy / Marie-Pierre Sunyach -- Pt. III Retinoblastoma -- 10. Retinoma and Retinoblastoma: Genomic Hybridisation / Alessandra Renieri -- 11. Cell Cycle Control by Ataxia Telangiectasia Mutated Protein Through Regulating Retinoblastoma Protein Phosphorylation / Jaume Folch -- 12. Role of Survivin in Retinoblastoma: Diagnosis and Prognosis / Eman Elsayed -- 13. Retinoblastoma Epigenetics / Giovanni Grasso -- 14. Retinoblastoma: Disease, Diagnosis, Therapy and Management / Vikas Khetan -- 15. Long-Term Survivors of Retinoblastoma: Risk of Increased Second Malignancy / Flora E. van Leeuwen -- 16. New Cancers Among Long-Term Survivors of Retinoblastoma / Alessandro Franchi -- Pt. IV Chordoma -- 17. Chordoma: Role of CAM5.2 / Takahiko Naka -- 18. Chordomas and Chondrosarcomas: Treatment with Particle Radiotherapy / Daniela Schulz-Ertner -- 19. Skull Base Chordomas: Endonasal Endoscopic Transclival Approach / Theodore H. Schwartz -- Pt. V Craniopharyngioma -- 20. Craniopharyngioma: Comparison Between Supra-orbital Versus Endonasal Keyhole Approaches / Daniel F. Kelly -- 21. Expanded Endoscopic Endonasal Approach for Primary and Recurrent Craniopharyngiomas / Amin B. Kassam -- 22. Craniopharyngioma: The Role of Radiation / Martin Pavelic -- 23. Cystic Craniopharyngiomas: Intratumoral Bleomycin Therapy / Juliette Hukin -- Pt. VI Oligodendroglioma -- 24. Anaplastic Oligodendroglioma Metastasized to Extraneural Sites / Mara Popovic -- 25. Recurrent Oligodendroglioma: Treatment with Bevacizumab / Marc C. Chamberlain -- Pt. VII Ependymoma -- 26. Ependymoma: An Overview / Paul Graham Fisher -- 27. Ependymomas: Prognosis Based on Genetic Aberrations / Gentner Doreen -- 28. Aberrant DNA Methylation in Ependymomas / Hehuang Xie -- 29. Progressively Metastasizing Ependymoma: Genomic Aberrations / Till Milde -- 30. Extradural Ependymoma: Diagnosis Using Magnetic Resonance Imaging / Roberto Pallini -- 31. Primary Malignant Ependymoma of the Abdominal Cavity: Diagnosis / Wolf Mueller -- 32. Atypical Histologic Features and Patterns of Malignant Evolution in Tanycytic Ependymoma / Ekkehard Hewer -- 33. Intracranial Ependymoma: Role for Chemotherapy / Marc C. Chamberlain.
- Format
- e-Book
- Location
- Online
Vascular Diseases for the Non-Specialist : An Evidence-Based Guide
https://libcat.nshealth.ca/en/permalink/provcat41556
Tulio Pinho Navarro, Alan Dardik, Daniela Junqueira, Ligia Cisneros, editors.
--Cham:
Springer
, 2017.
- Available Online
- View e-Book
- Location
- Online
This book aims to provide non-specialist healthcare practitioners with current, focused and objective information on the most common vascular diseases encountered in daily clinical practice. In day-to-day clinical practice many healthcare practitioners do not have a working knowledge of the most common vascular diseases that frequently arise in patient care. Some of these topics include: aneurysms, peripheral arterial disease, diabetic foot, venous thromboembolism, cerebrovascular disease, aort…
- Available Online
- View e-Book
- Other Authors
- Navarro, Tulio Pinho
- Dardik, Alan
- Junqueira, Daniela
- Cisneros, Ligia
- Responsibility
- Tulio Pinho Navarro, Alan Dardik, Daniela Junqueira, Ligia Cisneros, editors
- Place of Publication
- Cham
- Publisher
- Springer
- Date of Publication
- 2017
- Physical Description
- 1 online resource (xv, 279 pages) : 46 illus., 39 illus. in color
- ISBN
- 9783319460598
- 9783319460574 (print ed.)
- Subjects (MeSH)
- Vascular Diseases - diagnosis
- Vascular Diseases - therapy
- Abstract
- This book aims to provide non-specialist healthcare practitioners with current, focused and objective information on the most common vascular diseases encountered in daily clinical practice. In day-to-day clinical practice many healthcare practitioners do not have a working knowledge of the most common vascular diseases that frequently arise in patient care. Some of these topics include: aneurysms, peripheral arterial disease, diabetic foot, venous thromboembolism, cerebrovascular disease, aortic dissection, and acute limb ischemia. These commonly encountered vascular diseases are becoming public health issues due to their high morbidity and mortality as well as increasing healthcare costs. Since patients with vascular diseases are often referred to non-specialists, the general practitioner must know how to proper handle the most common vascular diseases encountered in daily clinical practice. For each disease the concept, epidemiology, natural history, diagnosis and treatment are described, followed by essential advice on what the non-specialist can do for the patient and when to refer the patient to a specialist.
- Contents
- How to Make Decisions in Healthcare Practice? -- Anatomy of the Cardiovascular System -- Atherosclerosis -- Hemostasis and Anticoagulation Therapy -- Peripheral Artery Disease -- Acute Limb Ischemia -- Cerebrovascular Disease -- Abdominal Aortic Aneurysm -- Peripheral and Visceral Aneurysms -- Thoracic, Thoracoabdominal, and Iliac Artery Aneurysms -- Risk Factors and Prophylaxis of Deep Vein Thrombosis and Pulmonary Embolism -- Venous Thromboembolism: Diagnosis and Treatment -- Diabetic Foot -- Chronic Venous Disease and Varicose Veins -- Vascular Anomalies -- Aortic Dissection -- Lower Limb Ulcers -- Lymphedema and Erysipleas -- Clinical Treatment Of Vascular Diseases -- Appendix A: Doppler Ultrasound and Ankle–Brachial Pressure Index -- Appendix B: Vascular Imaging Techniques.
- Format
- e-Book
- Location
- Online
