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The ACL-deficient knee : a problem solving approach

https://libcat.nshealth.ca/en/permalink/provcat32332
Vicente Sanchis-Alfonso, Joan Carles Monllau, editors. --London: Springer , c2013.
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The ACL-Deficient Knee: A Problem Solving Approach, focuses on problem analysis and problem solving, as well as analyzing the possibility of prevention. In each chapter, the biomechanics, anatomy, etc. that are relevant to the topic are reviewed. There are chapters where highly specialized surgical techniques are presented (v. gr. double bundle reconstruction or meniscal transplant), as well as developing areas such as ACL tears in children, where we are finding a growing number of injuries due…
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Other Authors
Sanchis-Alfonso, Vicente
Monllau, Joan Carles
Responsibility
Vicente Sanchis-Alfonso, Joan Carles Monllau, editors
Place of Publication
London
Publisher
Springer
Date of Publication
c2013
Physical Description
1 online resource (lxxix, 414 p. : 237 ill., 178 ill. in color)
ISBN
9781447142706
Subjects (MeSH)
Anterior Cruciate Ligament - surgery
Anterior Cruciate Ligament - injuries
Ligaments - transplantation
Orthopedics - methods
Subjects (LCSH)
Orthopedics
Orthopedic surgery
Sports medicine
Abstract
The ACL-Deficient Knee: A Problem Solving Approach, focuses on problem analysis and problem solving, as well as analyzing the possibility of prevention. In each chapter, the biomechanics, anatomy, etc. that are relevant to the topic are reviewed. There are chapters where highly specialized surgical techniques are presented (v. gr. double bundle reconstruction or meniscal transplant), as well as developing areas such as ACL tears in children, where we are finding a growing number of injuries due to the increase of sports at early ages. These chapters are written by internationally renowned specialists who are pioneers in the topics analyzed. To further enhance the educational content, there is a collection of online step by step surgical technique videos that will allow the knee specialist to perform the techniques presented in this book.
Contents
FOREWORD I -- FOREWORD II -- Treatment ACL-injuries still an unsolved clinical problem? -- PREFACE -- Historical Aspects on Surgery for Anterior Cruciate Ligament Deficiency -- Evidence-Based Medicine. How Can we Use it to Guide our Practice? -- What have we learned from the Kaiser Permanente Anterior Cruciate Ligament Reconstruction Registry (KP ACLRR)? -- The Danish anterior cruciate ligament reconstruction registry. What we are doing, how we do it, and which would be the best way to do it -- ACL ruptures in the female athlete. Can we predict who is at increased risk and can we reduce noncontact injury rates? -- Anterior cruciate ligament surgery risk factors for development of osteoarthritis. What can we do to prevent it? -- The need for an objective measurement in-vivo of rotational stability of the ACL-deficient knee. How can we measure it? -- Guidelines for operative versus nonoperative management of ACL injuries -- The stimulation of healing of the anterior cruciate ligament. Research and clinical relevance -- ACL Primary Repair. What we did, the results and how it helps today to tailor treatments to the patient and the pathology -- Graft choice in ACL reconstruction. Which one and why? -- Graft healing in ACL reconstruction: Can we enhance it in clinical practice? -- Is double-bundle ACL reconstruction necessary? -- ACL injuries in skeletally immature patients and adolescents. How can we improve the high rate of poor outcomes? -- Indications for ancillary surgery in the ACL deficient knee -- Outpatient ACL surgery. Is it safe? -- Factors related to return to sport after ACL reconstruction: When is it safe? -- Return to sports after ACL reconstruction surgery. A risk for further joint injury? -- Psychological factors in the ACL reconstruction population. Are they predictive of patient outcomes? -- Acute anterior cruciate ligament tear surgery. Repair vs. reconstruction. When? -- Partial chronic anterior cruciate ligaments tears. What to do -- Chronic anterior cruciate ligament tear. Single-bundle ACL reconstruction. Anteromedial portal versus transfemoral outside-in versus transtibial drilling technique -- Anterior cruciate ligament tear. Rationale and indications for anatomic ACL reconstruction -- Clinical relevance of meniscus in the treatment of the ACL-deficient knee. The real value of meniscal transplantation -- Clinical relevance of chondral lesions in the treatment of the ACL-deficient knee: Microfracture technique -- The role of high-tibial osteotomy in the ACL-deficient knee -- ACL injuries combined with lateral and medial knee injuries. Acute vs. chronic injury. What to do -- ACL injuries in children.Treatment and Outcomes. Personal experience -- Combined anterior cruciate ligament reconstruction with patella tendon lengthening following a complex knee injury -- ACL graft failure -- Reducing the risk of a reinjury following ACL reconstruction. What factors should be used to allow unrestricted return to sports activities? -- Anterior knee pain after ACL reconstruction. How to avoid it -- Limitation of joint range of motion after surgery of the anterior cruciate ligament -- Septic arthritis after anterior cruciate ligament reconstruction -- Deep venous thrombosis and pulmonary thromboembolism after ACL reconstruction. What can we do to prevent it? -- VIDEO # 1 - ACL reconstruction augmentation technique AMB & PLB -- VIDEO # 2 - ACL reconstruction. The surgical technique -- VIDEO # 3 - Anatomic ACL reconstruction: (3-1) Anatomic single bundle ACL reconstruction, (3-2) Anatomic double bundle ACL reconstruction -- VIDEO # 4 Lateral meniscus transplantation. Surgical technique. Bonus track: medial and lateral meniscal implants (ACTIFIT) + ACL reconstruction (BTPB) -- VIDEO # 5 - What factors should be used to allow unrestricted return to sports activities?
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e-Book
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ACL Injury and Its Treatment

https://libcat.nshealth.ca/en/permalink/provcat40415
Mitsuo Ochi, Konsei Shino, Kazunori Yasuda, Masahiro Kurosaka, editors. --Tokyo: Springer Japan , c2016.
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This volume presents detailed information on surgically relevant anatomy and histology of the anterior cruciate ligament (ACL), biomechanics, diagnostics, and ACL reconstruction. In light of the growing body of evidence demonstrating the advantages of anatomic ACL reconstruction over traditional methods, there are also discussions of single anteromedial bundle reconstruction and anatomic ACL reconstruction with abundant descriptions of experimental and clinical studies. In addition, particular …
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Ochi, Mitsuo
Shino, Konsei
Yasuda, Kazunori
Kurosaka, Masahiro
Responsibility
Mitsuo Ochi, Konsei Shino, Kazunori Yasuda, Masahiro Kurosaka, editors
Place of Publication
Tokyo
Publisher
Springer Japan
Date of Publication
c2016
Physical Description
1 online resource (xiv, 562 p. : 255 illus., 182 illus. in color)
ISBN
9784431558583
9784431558569 (print ed.)
Subjects (MeSH)
Anterior Cruciate Ligament - injuries
Anterior Cruciate Ligament Reconstruction - methods
Anterior Cruciate Ligament - surgery
Knee Joint - anatomy & histology
Abstract
This volume presents detailed information on surgically relevant anatomy and histology of the anterior cruciate ligament (ACL), biomechanics, diagnostics, and ACL reconstruction. In light of the growing body of evidence demonstrating the advantages of anatomic ACL reconstruction over traditional methods, there are also discussions of single anteromedial bundle reconstruction and anatomic ACL reconstruction with abundant descriptions of experimental and clinical studies. In addition, particular attention is given not only to techniques such as ACL augmentation, bone-patella tendon-bone reconstruction and computer-assisted navigation, but it also presents expert analysis of revision of ACL reconstruction, complications, and the future perspectives of ACL reconstruction. Edited by authoritative orthopedic surgeon from the Japanese Orthopaedic Society of Knee, Arthroscopy and Sports Medicine (JOSKAS), this book provides up-to-date information for orthopedic surgeons and physical therapists specializing in the ACL. The research evidence will broaden readers' understanding and enable them to optimize outcomes for patients. As ACL rupture is a common injury especially for high-level athletes, it will also attract sports trainers and team physicians who are interested in a recent update on this field.
Contents
Part I. Anatomy and Histology of the ACL -- 1 Functional Anatomy of the ACL Fibers on the Femoral Attachment -- 2 The Anatomical Features of ACL Insertion Sites and Their Implications for Multi-Bundle Reconstruction -- 3 Discrepancy Between Macroscopic and Histological Observations -- 4 Tibial Insertion of the ACL: 3D-CT Images, Macroscopic, and Microscopic Findings -- 5 Mechanoreceptors in the ACL -- Part II. Biomechanics of the ACL -- 6 Mechanical Properties and Biomechanical Function of the ACL -- 7 Biomechanics of the Knee with Isolated One Bundle Tear of the Anterior Cruciate Ligament -- 8 Function and Biomechanics of ACL Remnant -- 9 Biomechanics of Single- and Double-Bundle ACL Reconstruction -- 10 ACL Injury Mechanisms -- Part III. Diagnostics of ACL Injury -- 11 Physical Examinations and Device Measurements for ACL Deficiency -- 12 Diagnostics of ACL Injury Using Magnetic Resonance Imaging (MRI) -- 13 Diagnosis of Injured ACL Using Three-Dimensional Computed Tomography: Usefulness for Preoperative Decision Making -- Part IV. Basic Knowledge of ACL Reconstruction -- 14 Graft Selection -- 15 Portal Placement -- 16 Femoral Bone Tunnel Placement -- 17 Tibial Bone Tunnel Placement in Double-Bundle Anterior Cruciate Ligament Reconstruction Using Hamstring Tendons -- 18 Tensioning and Fixation of the Graft -- 19 Tendon Regeneration after Harvest for ACL Reconstruction -- 20 Second-Look Arthroscopic Evaluation after ACL Reconstruction -- 21 Bone Tunnel Changes After ACL Reconstruction -- 22 Graft I impingement -- 23 Fixation Procedure -- Part V. Multiple bundle ACL Reconstruction -- 24 Single- vs. Double-Bundle ACL Reconstruction -- 25 Anatomic Double-Bundle Reconstruction Procedure -- 26 Triple-Bundle ACL Reconstruction with the Semitendinosus Tendon Graft -- Part VI. ACL Augmentation -- 27 History and Advantages of ACL Augmentation -- 28 Surgical Technique of ACL Augmentation -- Part VII. ACL Reconstruction Using Bone-Patella Tendon-Bone -- 29 An Overview -- 30 Anatomical Rectangular Tunnel ACL Reconstruction with a Bone-Patellar Tendon-Bone Graft -- 31 Rectangular vs. Round Tunnel -- Part VIII. Computer-Assisted Navigation in ACL Reconstruction -- 32 Intraoperative Biomechanical Evaluation Using a Navigation System -- 33 Application of Computer-Assisted Navigation -- Part IX. ACL Injury in Patients with Open Physes -- 34 ACL Reconstruction with Open Physes -- 35 Avulsion Fracture of the ACL -- Part X. Revision ACL Reconstruction -- 36 Double-Bundle Technique -- 37 Bone-Patellar Tendon-Bone Graft via Round Tunnel -- 38 Anatomical Revision ACL Reconstruction with Rectangular Tunnel Technique -- 39 One- vs. Two-Stage Revision Anterior Cruciate Ligament Reconstruction -- Part XI. Complications of ACL Reconstruction -- 40 Complications of ACL Reconstruction -- Part XII. Future of ACL Reconstruction -- 41 Future Challenges of Anterior Cruciate Ligament Reconstruction: Biological Modulation Using a Growth Factor Application for Enhancement of Graft Healing -- 42 Strategies to Enhance Biological Tendon-Bobe Healing in Anterior Cruciate Ligament Reconstruction -- 43 Tissue engineering approach for ACL healing.
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e-Book
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Acquired Neuromuscular Disorders : Pathogenesis, Diagnosis and Treatment

https://libcat.nshealth.ca/en/permalink/provcat40131
Corrado Angelini, editor. --Cham: Springer , c2016.
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This book provides state of the art information on the pathogenesis, diagnosis, and treatment of a range of inflammatory, autoimmune, and idiopathic neuromuscular disorders. The opening section discusses the differential diagnosis of acquired myopathies based on clinical, electrophysiological, muscle biopsy, and serological criteria, with special focus on the role of electromyography and antibody testing. Each of the relevant clinical entities is then discussed in detail, the coverage including…
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Other Authors
Angelini, Corrado
Responsibility
Corrado Angelini, editor
Place of Publication
Cham
Publisher
Springer
Date of Publication
c2016
Physical Description
1 online resource (xi, 288 p. : 43 illus., 27 illus. in color)
ISBN
9783319295145
9783319295121 (print ed.)
Subjects (MeSH)
Muscular Atrophy - etiology
Neuromuscular Diseases - diagnosis
Neuromuscular Diseases - pathology
Neuromuscular Diseases - therapy
Abstract
This book provides state of the art information on the pathogenesis, diagnosis, and treatment of a range of inflammatory, autoimmune, and idiopathic neuromuscular disorders. The opening section discusses the differential diagnosis of acquired myopathies based on clinical, electrophysiological, muscle biopsy, and serological criteria, with special focus on the role of electromyography and antibody testing. Each of the relevant clinical entities is then discussed in detail, the coverage including, for example, myasthenia gravis, polymyositis, immune-mediated neuropathies, multifocal motor neuropathies, amyotrophic lateral sclerosis, paraneoplastic neuropathies, and diabetic polyneuropathy. Clear guidance is provided on currently available treatments, with descriptions of the latest advances in physiotherapy, drug therapy, and respiratory care. Other features of this clinically oriented book are the inclusion of many illustrative case presentations and contributions by international authors from leading centers.
Contents
Part I. Diagnostic Tools -- 1 Autoantibodies in Neuromuscular Disorders -- 2 Electromyography -- 3 Imaging of the Muscle -- 4 Peripheral Nerve Ultrasound -- 5 Magnetic Resonance Imaging of the Peripheral Nerve -- Part II. Clinical Myology Entities -- 6 The Spectrum of Inflammatory Myopathies: Dermatomyositis, Polymyositis, Necrotizing Myositis, and Inclusion-Body Myositis -- 7 Necrotizing Autoimmune Myopathy -- 8 Statin Myopathy -- 9 Myasthenia Gravis -- 10 Acquired Autoimmune Rippling Muscles with Myasthenia Gravis -- 11 Endocrinological Myopathies -- 12 Vitamin D Deficiency in Muscle -- 13 Intensive Care Unit-Acquired Weakness -- Part III. Neurogenic Disorders -- 14 Idiopathic Chronic Immune-Mediated Neuropathies: Chronic Inflammatory Demyelinating Polyradiculoneuropathy and Multifocal Motor Neuropathy -- 15 Immune Neuropathies -- 16 Amyotrophic Lateral Sclerosis: Epidemiology and Risk Factors -- 17 Paraneoplastic Diseases of the Peripheral Nervous System -- 18 Diabetic Neuropathy -- 19 Infectious Neuropathies -- 20 Toxic Neuropathies.
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e-Book
Location
Online
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Acrodermatitis Enteropathica : A Clinician's Guide

https://libcat.nshealth.ca/en/permalink/provcat39294
Pooya Khan Mohammad Beigi, Emanual Maverakis. --Cham: Springer , c2015.
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Written by and for dermatologists, pediatric and obstetrics specialists. This book presents the groundbreaking work of Dr. Pooya Khan Mohammad Beigi M.D., whose clinical research study on Acrodermatitis Enteropathica (AE) is the largest ever conducted on this rare disorder. The only book of its kind to offer insights into AE, it not only includes dozens of high quality photographs, illustrations, and clinical tables, but also covers everything from the history of AE to categories of the disorde…
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Author
Khan Mohammad Beigi, Pooya
Other Authors
Maverakis, Emanual
Responsibility
Pooya Khan Mohammad Beigi, Emanual Maverakis
Place of Publication
Cham
Publisher
Springer
Date of Publication
c2015
Physical Description
1 online resource (xxi, 156 p. : 56 illus., 51 illus. in color)
ISBN
9783319178196
9783319178189 (print ed.)
Subjects (MeSH)
Acrodermatitis
Zinc - deficiency
Abstract
Written by and for dermatologists, pediatric and obstetrics specialists. This book presents the groundbreaking work of Dr. Pooya Khan Mohammad Beigi M.D., whose clinical research study on Acrodermatitis Enteropathica (AE) is the largest ever conducted on this rare disorder. The only book of its kind to offer insights into AE, it not only includes dozens of high quality photographs, illustrations, and clinical tables, but also covers everything from the history of AE to categories of the disorder, molecular analysis, epidemiology, disorder signs and symptoms, diagnosis, treatment, and more. Acrodermatitis Enteropathica is a rare disorder of zinc metabolism that occurs in one of two forms: inborn and acquired. If untreated, this disease is fatal and affected individuals may die within just a few years. Therefore, it is critical that physicians are aware of the signs and symptoms related to AE and the appropriate treatments available for patients.
Contents
[publisher supplied] 1. History of Acrodermatitis Enteropathica -- 2. Epidemiology and Etiology -- 2.1. Epidemiology -- 2.2. Etiology -- 2.2.1. Molecular Etiology of AE -- 2.2.2. Hypothetical Etiology 1: the Alteration of Zinc Bioavailability -- 2.2.3. Hypothetical Etiology 2: a Defective Zinc Transporter -- 2.2.4. Alternative Forms of AE-like Zinc Deficiencies -- 3. Analysis of Disorder -- 3.1. Clinical Forms of AE -- 3.2. Nomenclature of Zinc Deficiencies -- 3.3. Acquired Non-hereditary Zinc Deficiency -- 3.3.1. Zinc Deficient Maternal Breast Milk -- 3.3.2. Zinc Deficient Caused by Metabolism Disorders -- 4. Clinical Symptoms -- 5. Diagnosis -- 5.1. Laboratory Diagnosis of Zinc Deficiency -- 5.2. Histopathology -- 5.3. Biological Diagnosis of AE -- 5.4. Clinical Diagnosis -- 5.5. Molecular Diagnosis -- 5.6. Differential Diagnosis -- 6. Disease Course and Treatment -- 6.1. Treatment -- 7. The Role of Zinc in Different Body Systems -- 7.1. Biochemistry of Zinc Metabolism -- 7.2. Skin and Hair Physiology -- 7.3. Gastrointestinal System and Other Organs -- 7.4. Neurological Development, Growth, and Mental Status -- 7.5. Enzymes -- 7.6. Endocrine System -- 7.7. Metabolism of Nucleic Acids -- 7.8. Mitosis and Meiosis Cycles -- 7.9. Cell Membranes -- 7.10. Synthesis of Proteins and Collagen -- 7.11. Immune System -- 8. History of AE in Adults -- 9. Iranian Hospital Cases in Literature -- 9.1. Patient One -- 9.2. Patient Two -- 9.3. Patient Three -- 9.4. Patient Four -- 9.5. Zinc Deficiency Similarities to AE in Infants (Fifth Patient) -- 10. Clinical Research -- 10.1. Abstract -- 10.2. Synopsis of Study -- 10.3. Purpose of Study -- 10.4. The Considered Hypotheses -- 10.5. Introduction -- 10.5. Methods -- 10.6. Ethical Considerations -- 10.7. Results -- 10.8. Discussion -- 11. Evaluation of Symptoms in Razi Dermatology Hospital -- 12. Case Photos.
Format
e-Book
Location
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Advanced Techniques in Limb Reconstruction Surgery

https://libcat.nshealth.ca/en/permalink/provcat39405
Mehmet Kocaoglu, Hiroyuki Tsuchiya, Levent Eralp, editors. --Berlin, Heidelberg: Springer , c2015.
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As a result of recent advances in surgical techniques and implant technology it is now possible to perform limb reconstruction in patients with a range of congenital, posttraumatic, and postinfection pathologies. This book is a clear, practical guide to the state-of-the-art surgical procedures employed in limb reconstruction for diverse conditions. It includes precise descriptions of the techniques themselves, accompanied by numerous helpful drawings and photographs. Pearls and pitfalls are hig…
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Other Authors
Kocaoglu, Mehmet
Tsuchiya, Hiroyuki
Eralp, Levent
Responsibility
Mehmet Kocaoglu, Hiroyuki Tsuchiya, Levent Eralp, editors
Place of Publication
Berlin, Heidelberg
Publisher
Springer
Date of Publication
c2015
Physical Description
1 online resource (viii, 471 p. : 409 illus., 249 illus. in color)
ISBN
9783642550263
9783642550256 (print ed.)
Subjects (MeSH)
Limb Deformities, Congenital - surgery
Limb Salvage - methods
Orthopedic Procedures - methods
Abstract
As a result of recent advances in surgical techniques and implant technology it is now possible to perform limb reconstruction in patients with a range of congenital, posttraumatic, and postinfection pathologies. This book is a clear, practical guide to the state-of-the-art surgical procedures employed in limb reconstruction for diverse conditions. It includes precise descriptions of the techniques themselves, accompanied by numerous helpful drawings and photographs. Pearls and pitfalls are highlighted, and thorough advice is also provided on indications, preoperative planning, and postoperative follow-up. The editors have carefully selected the contributors based on their expertise, and many of the authors were themselves responsible for developing the techniques that they describe.
Contents
1 Lengthening over Nails (LON): Femur and Tibia -- 2 Combined Technique: Correction of Long Bone Deformities Using Fixator-Assisted Nailing -- 3 Femoral and Tibial Deformity Correction and Consecutive Lengthening over an Intramedullary Nail (FAN-LON) -- 4 Hybrid Lengthening Techniques: Lengthening and Then Nailing (LATN) and Lengthening and Then Plating (LAP) -- 5 Knee Arthrodesis with Monolateral External Fixator for the Treatment of Infected Knee Arthroplasty -- 6 Acute Temporary Malpositioning for Dealing with Extensive Tissue Loss After Severe High-Energy Trauma to Extremities -- 7 Salvage of Infected Periarticular Fractures -- 8 Reconstruction of Segmentary Defects in Chronic Osteomyelitis Using the Combined Technique -- 9 Reconstruction Techniques for Mega Bone Defects -- 10 Application of External Fixators for Reconstruction in Bone Tumor Surgery -- 11 Joint Contracture Management with External Fixators -- 12 Joint Distraction for Special Conditions -- 13 Lengthening Reconstruction Surgery for Congenital Femoral Deficiency -- 14 Congenital Pseudoarthrosis of the Tibia: Redefined (Congenital Crural Segmental Dysplasia) -- 15 Treatment of Tibial Hemimelia -- 16 Distraction Arthroplasty for Ankle Osteoarthritis -- 17 Hindfoot Reconstruction by the Combined Technique -- 18 Complex Foot Deformities: Correction with the Taylor Spatial Frame -- 19 Circular External Fixation of the Spine and Pelvis for Insoluble Spinal Deformities -- 20 Pelvic Inlet Reconstruction for Obstruction Associated with Lumbosacral Agenesis Utilizing Distraction Osteogenesis and Circular External Fixation -- 21 Pelvic Support Osteotomy (PSO): Indications, Limits and Complications.
Format
e-Book
Location
Online
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Alcohol, nutrition, and health consequences

https://libcat.nshealth.ca/en/permalink/provcat32449
Ronald Ross Watson, Victor R. Preedy, Sherma Zibadi, editors. --New York, NY: Humana Press , c2013.
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Alcohol, Nutrition, and Health Consequences provides practical, data-driven resources to help the reader understand the basics, treatments and preventive strategies that are involved in the understanding of how alcohol may affect healthy individuals as well as those with chronic alcohol use with or without relevant infectious diseases, obesity, diabetes and/or neurocognitive declines. It will also help the clinician define the causes and types of nutritional changes due to alcohol use and also …
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Other Authors
Watson, Ronald Ross
Preedy, Victor R
Zibadi, Sherma
Responsibility
Ronald Ross Watson, Victor R. Preedy, Sherma Zibadi, editors
Place of Publication
New York, NY
Publisher
Humana Press
Date of Publication
c2013
Physical Description
1 online resource (xxi, 578 p. : 70 ill., 8 ill. in color)
Series
Nutrition and Health
Series Title
Nutrition and health (Totowa, N.J.)
ISBN
9781627030472
Subjects (MeSH)
Alcohol-Related Disorders - complications
Ethanol - adverse effects
Ethanol - metabolism
Nutrition Disorders - etiology
Nutritional Physiological Phenomena
Subjects (LCSH)
Nutrition
Personal health and hygiene
Emergency medicine
Abstract
Alcohol, Nutrition, and Health Consequences provides practical, data-driven resources to help the reader understand the basics, treatments and preventive strategies that are involved in the understanding of how alcohol may affect healthy individuals as well as those with chronic alcohol use with or without relevant infectious diseases, obesity, diabetes and/or neurocognitive declines. It will also help the clinician define the causes and types of nutritional changes due to alcohol use and also explain how nutrition can be used to ameliorate its consequences. Chapters present the application of current nutritional knowledge by physicians and dietitians. Specific areas involving alcohol-related damage due to nutritional changes are reviewed, including heart disease, obesity, digestive tract cancers, lactation, brain function, and liver disease. In addition, alcohol's effects on absorption of minerals and nutrients, a key role in causing damage are treated. The importance of diet in modifying alcohol and its metabolite damage is also explained. Alcohol, Nutrition, and Health Consequences is essential reading for alcohol therapists and researchers as well as primary care physicians and dietitians and is an easy reference to help the clinician, student, and dietitian comprehend the complex changes caused by direct and indirect effects of ethanol at the cellular level via its nutritional modification.
Contents
Alcoholic and Nutrition: an Overview -- Genetics of alcohol metabolism -- Laboratory models available to study alcohol and nutrition -- Ethanol-induced lipid peroxidation and apoptosis in embryopathy -- Alcohol Use During Lactation: Effects on the Mother Infant Dyad -- Moderate alcohol administration: oxidative stress and nutritional status -- Alcohol use and abuse: Effects on Body Weight and body composition -- Alcohol Nutrition and health inequalities -- The effect of diet on protein modification by ethanol metabolites -- Vitamin B12 deficiency in alcoholics -- Alcohol American Indians/Alaskan Natives and Alcohol: Biology, Nutrition and Positive Programs -- Metabolism of Ethanol to Acetaldehyde in the Rat Mammary Tissue. Inhibitory Effects of Plant Polyphenols and Folic Acid -- Dietary zinc supplementation and prenatal ethanol exposure -- Tocotrienol and cognitive dysfunction induced by alcohol -- Soy Products Affecting Alcohol Absorption and Metabolism -- Oats supplementation and alcohol-induced oxidative tissue damage -- Fish oil n-3 fatty acids to prevent hippocampus and cognitive dysfunction in experimental alcoholism -- Alcohol in HIV and possible interactions with antiretroviral medications -- Popular energy drinks and alcohol -- The psychological synergistic effects of alcohol and caffeine -- Alcohol and Smoking: A correlation of use in youth? -- Are there Physiological Correlations between alcohol and tobacco use in adults? -- Alcohol, HIV/AIDS and Liver Disease -- Nutritional status, socioeconomic factors, alcohol and cataracts -- Alcohol Intake and High Blood Pressure -- Alcohol and dyslipidemia -- Dietary antioxidants in chronic alcoholic pancreatitis -- Alcohol consumption, lifestyle factors and risk of type 2 diabetes -- Alcohol, overweight, and obesity -- Nutrition alcohol and anorectic and bulimic adolescents -- Viral infections and cancer during alcohol use -- Ethanol and hepatocarcinogenesis -- Alcohol, diet and their interaction in colorectal and urinary tract tumors -- Alcohol, acetaldehyde and digestive tract cancer -- Alcohol Intake and Esophageal Cancer: Epidemiologic Evidence -- A Nutritional approach to prevent alcoholic liver disease -- Nutraceutical potential of indigenous plant foods and herbs for treatment of alcohol related Liver damage -- Alcohol and nutrition as risk factors for chronic liver disease -- Alcohol-related liver disease: Roles of insulin resistance, lipotoxic ceramide accumulation and endoplasmic reticulum stress -- Nutrition and alcoholic and non-alcoholic fatty liver disease: The significance of cholesterol -- Dietary fatty acids and alcoholic liver disease -- Nutrition in alcoholic steatohepatitis -- Alcoholic and non-alcoholic fatty liver disease and vitamin A.
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e-Book
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Alcohol use disorders and the lung : a clinical and pathophysiological approach

https://libcat.nshealth.ca/en/permalink/provcat33180
edited by David M. Guidot, Ashish J. Mehta. --New York, NY: Humana Press , c2014.
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Alcohol Use Disorders and the Lung: A Clinical and Pathophysiological Approach is an excellent resource for clinicians who care for individuals affected by alcohol use disorders in diverse settings. Although alcohol abuse alone does not cause acute lung injury, it renders the lung susceptible to dysfunction in response to the inflammatory stresses of sepsis, trauma, and other clinical conditions recognized to cause acute lung injury. In parallel, these same pathophysiological effects of alcoho…
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Other Authors
Guidot, David M
Mehta, Ashish J
Responsibility
edited by David M. Guidot, Ashish J. Mehta
Place of Publication
New York, NY
Publisher
Humana Press
Date of Publication
c2014
Physical Description
1 online resource (x, 252 p.)
Series Vol.
14
Series Title
Respiratory medicine (New York, N.Y.)
ISBN
9781461488330 (electronic bk.)
Subjects (MeSH)
Alcohol Drinking - adverse effects
Alcohol-Related Disorders - complications
Lung Diseases
Subjects (LCSH)
Alcohol - Physiological effect
Alcoholism - Complications
Lungs - Diseases
Abstract
Alcohol Use Disorders and the Lung: A Clinical and Pathophysiological Approach is an excellent resource for clinicians who care for individuals affected by alcohol use disorders in diverse settings. Although alcohol abuse alone does not cause acute lung injury, it renders the lung susceptible to dysfunction in response to the inflammatory stresses of sepsis, trauma, and other clinical conditions recognized to cause acute lung injury. In parallel, these same pathophysiological effects of alcohol abuse significantly increase the risk of a wide range of serious lung infections. Many clinicians involved in the primary treatment of alcohol use disorders, such as addiction psychiatrists, will find this text of interest as it will expand their understanding of the health consequences of alcohol use disorders. In parallel, clinicians who specialize in pulmonary and/or critical care medicine will have a unique resource that provides a comprehensive review of the pathophysiology of alcohol-related lung disorders and insights into evolving therapeutic options in these vulnerable individuals. Alcohol Use Disorders and the Lung: A Clinical and Pathophysiological Approach fills a gap in the literature and presents the evolving clinical research that may soon lead to novel therapies that can improve lung health in individuals with alcohol use disorders and co-existing conditions such as HIV infection.
Contents
A Brief History of Alcohol Use and Abuse in Human History -- Overview of the Evolving Recognition of the Health Effects of Excessive Alcohol Use Over the Past Two Centuries Including the Classic Citations -- Current Definitions of Alcohol Use Disorders and the Use of Validated Questionnaires in Clinical Practice and Research -- The Epidemiology of Alcohol Abuse and Pneumonia -- The Epidemiology of Alcohol and Acute Respiratory Distress Syndrome -- Alcohol, the Upper Airway, and Mucociliary Dysfunction in the Conducting Airways -- Alcohol and the Alveolar Macrophage -- Alcohol and the Alveolar Epithelium -- Alcohol-Mediated Oxidative Stress in the Airway: The Unique Role of Thiol Depletion -- Alcohol and the Adaptive Immune Response in the Airway: Dendritic Cell and Lymphocyte Impairments -- Alcohol Impairment of Granulocyte Function During Lung Infection -- Disruption in the Dynamic Balance Between Transforming Growth Factor- and Granulocyte/Macrophage Colony-stimulating Factor Signaling within the Alveolar Space of the Alcoholic Lung: Impact on Epithelial and Macrophage Function -- Alcohol-mediated Zinc Deficiency within the Alveolar Space: A Potential Fundamental Mechanism Underlying Oxidative Stress and Cellular Dysfunction in the Alcoholic Lung -- The Impact of Alcohol Abuse on Multiple Organ Dysfunction in the Surgical Patient -- Alcohol and HIV: Experimental and Clinical Evidence of Combined Impact on the Lung -- Maternal Alcohol Use and the Neonate.
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e-Book
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Aliments riches en potassium

https://libcat.nshealth.ca/en/permalink/chpams37332
Nova Scotia Health Authority. Nutrition and Food Services. Halifax, NS: Nova Scotia Health Authority , 2020.
Pamphlet Number
2181
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Tous les fruits et légumes contiennent du potassium. Ce dépliant fournit une liste d'aliments à forte teneur en potassium. Si vous avez un taux de potassium élevé dans le sang, vous devez éviter ces aliments. Si vous avez un faible taux de potassium dans le sang, vous devriez choisir un plus grand nombre de ces aliments chaque jour. ; This pamphlet is a French translation of "Foods High in Potassium" pamphlet 0610. All fruits and vegetables have potassium. This pamphlet provides a list of foods…
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Corporate Author
Nova Scotia Health Authority. Nutrition and Food Services
Alternate Title
Foods high in potassium
Place of Publication
Halifax, NS
Publisher
Nova Scotia Health Authority
Date of Publication
2020
Format
Pamphlet
Language
French
Physical Description
1 electronic document ([2] p.) : digital, PDF file
Subjects (MeSH)
Potassium Deficiency
Potassium, Dietary
Subjects (LCSH)
High-potassium diet
Potassium deficiency diseases
Specialty
Food and Nutrition
Abstract
Tous les fruits et légumes contiennent du potassium. Ce dépliant fournit une liste d'aliments à forte teneur en potassium. Si vous avez un taux de potassium élevé dans le sang, vous devez éviter ces aliments. Si vous avez un faible taux de potassium dans le sang, vous devriez choisir un plus grand nombre de ces aliments chaque jour.
This pamphlet is a French translation of "Foods High in Potassium" pamphlet 0610. All fruits and vegetables have potassium. This pamphlet provides a list of foods that are high in potassium. If you have high blood potassium levels, you should avoid these foods. If you have low blood potassium levels, you should choose more of these foods daily.
Responsibility
Prepared by: Nutrition and Food Services
Pamphlet Number
2181
Less detail

Allergies and Adolescents : Transitioning Towards Independent Living

https://libcat.nshealth.ca/en/permalink/provcat42970
edited by David R. Stukus. --Cham: Springer , c2018.
Available Online
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Location
Online
This unique book is intended to assist readers in understanding various allergic diseases as they pertain to the adolescent, with a strong focus on encouraging their transition into self-management. Allergies and Adolescents thoroughly addresses both the cognitive and social development of adolescents and provides effective strategies for involving them in their own self-management. Different types of nonadherence are covered in detail, and specific conditions such as allergic rhinitis, asthma,…
Available Online
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Other Authors
Stukus, David R.
Responsibility
edited by David R. Stukus
Place of Publication
Cham
Publisher
Springer
Date of Publication
c2018
Physical Description
1 online resource (xiv, 246 p.) : 19 illus. in color
ISBN
9783319774855
9783319774848 (print ed.)
9783319774862 (print ed.)
Subjects (MeSH)
Allergens
Adolescent
Specialty
Adolescent Health
Allergy and Immunology
Abstract
This unique book is intended to assist readers in understanding various allergic diseases as they pertain to the adolescent, with a strong focus on encouraging their transition into self-management. Allergies and Adolescents thoroughly addresses both the cognitive and social development of adolescents and provides effective strategies for involving them in their own self-management. Different types of nonadherence are covered in detail, and specific conditions such as allergic rhinitis, asthma, food allergy, and eczema each have a chapter devoted to a comprehensive discussion of basic concepts surrounding diagnosis and management. These chapters are then followed by a separate chapter providing details as to how that condition can specifically impact adolescents. Chapters containing practical tips that can be immediately implemented by adolescents and their families as well as clinicians conclude the book. Written by experts in their respective fields, Allergies and Adolescents is a comprehensive resource for multiple audiences, including the allergist, pediatrician, and any other healthcare provider working with adolescents, guiding them towards self-management, and preparing them for independent living.
Contents
1. The Allergy Epidemic -- 2. Adolescent Brain Development and Implications for Adolescents with Allergies -- 3. How Can We Best Communicate with Adolescents? -- 4. The Many Faces of Nonadherence in Adolescents -- 5. Allergic Rhinitis -- 6. Allergic Rhinitis Pertaining to Adolescents -- 7. Asthma: A Heterogeneous and Challenging Chronic Condition -- 8. Managing Adolescent Asthma: More than Just Medications -- 9. Food Allergies: An Overview -- 10. Food Allergies and the Teenager -- 11. Atopic Dermatitis: Overview -- 12. Atopic Dermatitis Pertaining to Adolescents -- 13. her Allergic Conditions: Venom Hypersensitivity, Drug Allergy, Chronic Urticaria/Angioedema, Primary Immune Deficiency -- 14. at Now? Practical Steps for Adolescents with Allergies and Asthma to Manage Their Healthcare Independently -- 15. Practical Approach for Clinicians to Prepare -- Adolescents for Independent Living.
Format
e-Book
Location
Online
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Alpha-1 Antitrypsin : Role in Health and Disease

https://libcat.nshealth.ca/en/permalink/provcat39919
Adam Wanner, Robert A. Sandhaus, editors. (1st ed.) --Cham: Springer International Publishing : Imprint: Humana Press , c2016.
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Location
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This book offers a comprehensive overview of alpha-1 antitrypsin deficiency, an inherited condition that leads to lung disease in adults and liver disease in adults and children. While it is a rare condition, the mechanisms underlying its clinical manifestations have been largely clarified. Specific treatment, however, is available only for the lung disease that arises from the condition, thus necessitating continued research into new and alternative therapeutic solutions. The book discusses th…
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Other Authors
Wanner, Adam
Sandhaus, Robert A
Responsibility
Adam Wanner, Robert A. Sandhaus, editors
Edition
1st ed.
Place of Publication
Cham
Publisher
Springer International Publishing : Imprint: Humana Press
Date of Publication
c2016
Physical Description
1 online resource (x, 173 p. : 27 illus., 12 illus. in color)
Series Title
Respiratory medicine
ISBN
9783319234496
9783319234489 (print ed.)
ISSN
2197-7372
Subjects (MeSH)
Serine Proteinase Inhibitors
alpha 1-Antitrypsin Deficiency
alpha 1-Antitrypsin
Abstract
This book offers a comprehensive overview of alpha-1 antitrypsin deficiency, an inherited condition that leads to lung disease in adults and liver disease in adults and children. While it is a rare condition, the mechanisms underlying its clinical manifestations have been largely clarified. Specific treatment, however, is available only for the lung disease that arises from the condition, thus necessitating continued research into new and alternative therapeutic solutions. The book discusses the biology of alpha-1 antitrypsin, protein misfolding and polymerization, and diagnosis and treatment of alpha-1 antitrypsin deficiency and its associated diseases. It concludes with a discussion of alpha-1 antitrypsin therapy in diseases not associated with alpha-1 antitrypsin deficiency, and the role of healthcare organizations in the rare disease space. Written for pulmonary clinicians and scientists, Alpha-1 Antitrypsin: Role in Health and Disease is a valuable resource that sheds light on this rare disease.
Contents
Alpha-1- Antitrypsin and the Serpins -- Alpha-1 Antitrypsin: The protein -- Misfolding and Polymerisation of Alpha1-Antitrypsin: Conformational Pathology and Therapeutic Targeting -- Managing the Adaptive Proteostatic Landscape: Restoring Resilience in Alpha-1 Antitrypsin Deficiency -- United States Targeted Detection Program for Alpha-1 Antitrypsin Deficiency -- Lung Disease of Alpha-1 Antitrypsin Deficiency -- Alpha-1-Antitrypsin Deficiency: Role in Health and Disease -- Alpha-1 Antitrypsin as a Therapeutic Agents for Conditions not Associated with Alpha-1 Antitrypsin Deficiency -- The Alpha-1 Constellation of Voluntary Health Organizations as a Paradigm for Confronting Other Rare Diseases.
Format
e-Book
Location
Online
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Androgen deficiency and testosterone replacement : current controversies and strategies

https://libcat.nshealth.ca/en/permalink/provcat32455
Wayne J.G. Hellstrom, editor. --New York, NY: Humana Press , c2013.
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Location
Online
Androgen Deficiency and Testosterone Replacement: Current Controversies and Strategies explores the difficulties around the diagnosis and treatment of androgen deficiency. The text examines the available evidence concerning the diagnosis and treatment of men with low testosterone. It also examines controversies in the identification and management of these men. While the information contained within will be of use to those who specialize in androgen deficiency and sexual medicine, the scope of …
Available Online
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Other Authors
Hellstrom, Wayne J.G
Responsibility
Wayne J.G. Hellstrom, editor
Place of Publication
New York, NY
Publisher
Humana Press
Date of Publication
c2013
Physical Description
1 online resource (x, 154 p. : 17 ill., 10 ill. in color)
Series Title
Current clinical urology
ISBN
9781627031790
Subjects (MeSH)
Androgens - deficiency
Hypogonadism - therapy
Testosterone - therapeutic use
Subjects (LCSH)
Endocrinology 
Urology
Abstract
Androgen Deficiency and Testosterone Replacement: Current Controversies and Strategies explores the difficulties around the diagnosis and treatment of androgen deficiency. The text examines the available evidence concerning the diagnosis and treatment of men with low testosterone. It also examines controversies in the identification and management of these men. While the information contained within will be of use to those who specialize in androgen deficiency and sexual medicine, the scope of the book will serve as a source of basic information about testosterone replacement and as a source of reasoned analysis of the controversies surrounding testosterone replacement in the aging male. Physicians and physician extenders will be able to apply evidence management principles to the evaluation and treatment of men with testosterone deficiency; supported by the most recent practice guidelines available. The authors represent a select group of physicians with expertise in androgen deficiency and replacement. Androgen Deficiency and Testosterone Replacement: Current Controversies and Strategies will be of great value to all physicians and physician extenders who deliver health care to men of all ages.
Contents
The Institute of Medicine White Paper on Testosterone: Current Perspective -- The Laboratory Diagnosis of Testosterone Deficiency -- The Clinical Diagnosis of Androgen Deficiency -- The Use of Patient Reported Outcome Questionnaires in the Diagnosis of Androgen Deficiency -- Testosterone, and its Association with Metabolic and Cardiovascular Disease -- The Role of Androgens in Prostate Cancer -- Androgen Deficiency in the Adolescent Male -- Effects of Androgen Deficiency and Replacement on Male Fertility -- HIV and Testosterone in Men -- Treatment Options for Testosterone Replacement Therapy -- Alternate Therapies for Testosterone Replacement.
Format
e-Book
Location
Online
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An evidence-based approach to vitamins and minerals : health benefits and intake recommendations

https://libcat.nshealth.ca/en/permalink/provcat31294
Jane Higdon, Victoria J. Drake. (2nd ed.) --Stuttgart: Thieme , c2012.
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Location
Online
This evidence-based reference, now in a second edition, presents the most current scientific, epidemiological and clinical research on the role of vitamins and minerals in preventing disease and promoting optimal health. Organized by micronutrient, the book covers biological function, deficiency, recommended daily allowance, role in disease prevention and treatment, sources, safety, and interactions with other micronutrients and drugs--all endorsed by the internationally acclaimed Linus Paulin…
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Author
Higdon, Jane
Other Authors
Drake, Victoria J.
Responsibility
Jane Higdon, Victoria J. Drake
Edition
2nd ed.
Place of Publication
Stuttgart
Publisher
Thieme
Date of Publication
c2012
Physical Description
1 online resource (xxii, 282 p.)
ISBN
9783131324528
9783131644725 (eISBN)
Subjects (MeSH)
Vitamins - therapeutic use
Dietary Supplements
Nutritional Requirements
Recommended Dietary Allowances
Specialty
Nutritional Sciences
Abstract
This evidence-based reference, now in a second edition, presents the most current scientific, epidemiological and clinical research on the role of vitamins and minerals in preventing disease and promoting optimal health. Organized by micronutrient, the book covers biological function, deficiency, recommended daily allowance, role in disease prevention and treatment, sources, safety, and interactions with other micronutrients and drugs--all endorsed by the internationally acclaimed Linus Pauling Institute at Oregon State University.
Format
e-Book
Location
Online
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Answers to your questions about a positive newborn screening result for Biotinidase Deficiency

https://libcat.nshealth.ca/en/permalink/chpams38000
Maritime Newborn Screening Program, IWK. Transfusion Medicine Service - (Lab Services). Halifax, NS: IWK Health Centre , 2019.
Pamphlet Number
PL-1128
Available Online
View Pamphlet
What is the Maritime Newborn Screening service? Who, what, why and how baby is tested; explanation of disorders and test results.
Available Online
View Pamphlet
Corporate Author
Maritime Newborn Screening Program
IWK. Transfusion Medicine Service - (Lab Services)
Alternate Title
Information for Parents
Maritime Newborn Screening Program
Place of Publication
Halifax, NS
Publisher
IWK Health Centre
Date of Publication
2019
Format
Pamphlet
Language
English
Physical Description
1 electronic document : digital, PDF file
Subjects (MeSH)
Neonatal Screening
Subjects (LCSH)
Newborn infants--Diseases--Diagnosis
Newborn screening
Abstract
What is the Maritime Newborn Screening service? Who, what, why and how baby is tested; explanation of disorders and test results.
Responsibility
Maritime Newborn Screening Program, Halifax, NS
Pamphlet Number
PL-1128
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Asthma, Allergic and Immunologic Diseases During Pregnancy : A Guide to Management

https://libcat.nshealth.ca/en/permalink/provcat44228
Jennifer A. Namazy, Michael Schatz, editors. --Cham: Springer , 2019.
Available Online
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Location
Online
With insight and research from world-renowned experts, this book provides specific approaches to diagnosis and treatment, addressing pharmacologic and non-pharmacologic management. Specific conditions examined include asthma, rhinitis and sinusitis, anaphylaxis, atopic and contact dermatitis, urticaria and angioedema, hereditary angioedema, drug allergies, and primary immune deficiency. An overview of obstetric management of the high risk asthmatic and allergic patient is provided, and the book…
Available Online
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Other Authors
Namazy, Jennifer A.
Schatz, Michael
Responsibility
Jennifer A. Namazy, Michael Schatz, editors
Place of Publication
Cham
Publisher
Springer
Date of Publication
2019
Physical Description
1 online resource (x, 251 p.) : 13 illus., 10 illus. in color
ISBN
9783030033958
9783030033941 (Print ed.)
9783030033965 (Print ed.)
Subjects (MeSH)
Asthma
Hypersensitivity
Immune Complex Diseases
Pregnancy Complications - immunology
Pregnancy Complications - therapy
Obstetrics - methods
Specialty
Allergy and Immunology
Obstetrics
Abstract
With insight and research from world-renowned experts, this book provides specific approaches to diagnosis and treatment, addressing pharmacologic and non-pharmacologic management. Specific conditions examined include asthma, rhinitis and sinusitis, anaphylaxis, atopic and contact dermatitis, urticaria and angioedema, hereditary angioedema, drug allergies, and primary immune deficiency. An overview of obstetric management of the high risk asthmatic and allergic patient is provided, and the book concludes with a discussion of the prevention of asthma and allergic diseases during childhood.
Contents
1. Non-pharmacologic Aspects of Management: “Asthma and Allergic and Immunologic Diseases During Pregnancy – A Guide to Management” -- 2. Safety of Asthma and Allergy Medications During Pregnancy -- 3. Asthma: Interrelationships with Pregnancy -- 4. Asthma: Management -- 5. Rhinitis and Sinusitis -- 6. Anaphylaxis in Pregnancy -- 7. Atopic Dermatitis and Allergic Contact Dermatitis in Pregnancy -- 8. Urticaria and Angioedema -- 9. Hereditary Angioedema -- 10. Drug Hypersensitivity -- 11. Primary Immunodeficiencies in Pregnancy -- 12. Obstetric Management of High-Risk Asthmatic, Allergic Patients and Anaphylaxis -- 13. Prevention of Asthma and Allergic Diseases During Childhood.
Format
e-Book
Location
Online
Less detail

Atlas of Diabetes

https://libcat.nshealth.ca/en/permalink/provcat30932
edited by Jay Skyler. (4th ed.) --New York, NY: Springer , c2012.
Available Online
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Location
Online
Diabetes mellitus is increasing in incidence, prevalence, and importance as a chronic disease throughout the world. The International Diabetes Federation projects that by 2030 there will be 438 million people with diabetes on a global scale. In the United States, the Centers for Disease Control calculates that 25.8 million people (or 8.3% of the population) have diabetes and nearly 2 million Americans develop diabetes each year. Thus, the burden of diabetes is enormous in terms of the magnitude…
Available Online
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Other Authors
Skyler, Jay
Responsibility
edited by Jay Skyler
Edition
4th ed.
Place of Publication
New York, NY
Publisher
Springer
Date of Publication
c2012
Physical Description
1 online resource (x, 422 p. : 502 ill., 395 ill. in color)
ISBN
9781461410287
Subjects (MeSH)
Diabetes Mellitus - Atlases
Subjects (LCSH)
Diabetes
Abstract
Diabetes mellitus is increasing in incidence, prevalence, and importance as a chronic disease throughout the world. The International Diabetes Federation projects that by 2030 there will be 438 million people with diabetes on a global scale. In the United States, the Centers for Disease Control calculates that 25.8 million people (or 8.3% of the population) have diabetes and nearly 2 million Americans develop diabetes each year. Thus, the burden of diabetes is enormous in terms of the magnitude of the population affected. There has been an exciting explosion of knowledge about fundamental mechanisms related to diabetes. We have gained insights into the pathogenesis both of type 1 and type 2 diabetes, and with that, the prospect of implementing prevention strategies to delay or interdict the disease processes. Great progress has been made in islet transplantation, which offers the potential of reversing diabetes, while approaches to islet replacement by regeneration or stem cell therapy are in their infancy. Whether diabetes prevention will come from advances in understanding the processes of islet neogenesis and proliferation, from genetic engineering, or from protecting xenoislets or stem cells from immunologic attack remains unclear. All are potential avenues of pursuit. This newly revised, comprehensive, four-color Atlas of Diabetes, 4th Edition, is extensively updated with references to the current literature. Developed by leading authorities in the field, this Atlas offers an indispensable collection of images, including algorithms, tables, charts, and schematic drawings. It continues its role as a leading reference work and an invaluable contribution to the field.
Contents
Regulation of Insulin Secretion and Islet Cell Function -- Mechanisms of Insulin Action -- Consequences of Insulin Deficiency -- Type 1 Diabetes -- Management of Type 1 Diabetes -- Childhood Diabetes -- Pathogenesis of Type 2 Diabetes -- Management of Type 2 Diabetes Mellitus -- Diabetes and Pregnancy -- Mechanisms of Hyperglycemic Damage in Diabetes -- Management and Prevention of Diabetic Complications -- Eye Complications of Diabetes -- Diabetes and the Kidney -- Diabetic Neuropathies -- Obesity Therapy -- Reversal of Diabetes: Islet Cell Transplantation -- Technology and Diabetes: Insulin Delivery Systems and Glucose Sensing -- Newer Diabetes Medications.
Format
e-Book
Location
Online
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Atlas of Genetic Diagnosis and Counseling

https://libcat.nshealth.ca/en/permalink/provcat41222
Harold Chen. (Third edition) --New York, NY: Springer , 2017.
Available Online
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Location
Online
Dr. Harold Chen shares his almost 50 years of clinical genetics practice in this new edition of a comprehensive pictorial atlas, featuring almost 290 genetic disorders, malformations, and malformation syndromes. The author provides a detailed outline for each disorder, describing its genetics, basic defects, clinical features, diagnostic tests, and counseling issues, including recurrence risk, prenatal diagnosis, and management. Numerous color photographs of prenatal ultrasounds, imagings, cyto…
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Author
Chen, Harold
Responsibility
Harold Chen
Edition
Third edition
Place of Publication
New York, NY
Publisher
Springer
Date of Publication
2017
Physical Description
1 online resource (xxiii, 3080 pages) : 1242 illus., 1050 illus. in color
Series Title
Springer reference
ISBN
9781493924011
9781493924004 (print ed.)
Subjects (MeSH)
Genetic Counseling
Genetic Diseases, Inborn
Prenatal Diagnosis
Abstract
Dr. Harold Chen shares his almost 50 years of clinical genetics practice in this new edition of a comprehensive pictorial atlas, featuring almost 290 genetic disorders, malformations, and malformation syndromes. The author provides a detailed outline for each disorder, describing its genetics, basic defects, clinical features, diagnostic tests, and counseling issues, including recurrence risk, prenatal diagnosis, and management. Numerous color photographs of prenatal ultrasounds, imagings, cytogenetics, and postmortem findings illustrate the clinical features of patients at different ages, patients with varying degrees of severity, and the optimal diagnostic strategies. The disorders cited are supplemented by case histories and diagnostic confirmation by cytogenetics, biochemical, and molecular techniques, when available. Since the publication of the previous edition in 2012, the atlas has been widely accepted and used in light of rapid progress in genetic and gnomic information. In this new edition, additional genetic disorders are added, as well as extensive updates to the previous disorders with new illustrations, supplemented by case and family history, clinical features, and laboratory data, especially molecular confirmation if available. The atlas is written in outline format for ease of use. Atlas of Genetic Diagnosis and Counseling, Third Edition is of great value to medical geneticists, genetic counselors, pediatricians, neonatologists, developmental pediatricians, perinatologists, obstetricians, neurologists, pathologists, and any physicians and health care professionals caring for handicapped children such as craniofacial surgeons, plastic surgeons, otolaryngologists, and orthopedists. It is the definitive volume for helping all physicians to understand and recognize genetic diseases and malformation syndrom es and better evaluate, counsel, and manage affected patients.
Contents
Acardia -- Achondrogenesis -- Achondroplasia -- Adams-Oliver Syndrome -- Agnathia -- Aicardi Syndrome -- Alagille Syndrome -- Albinism -- Alpha-Thalassemia X-linked Mental Retardation Syndrome -- Ambiguous Genitalia -- Amniotic Deformity, Adhesions, Mutilations (ADAM) Complex -- Androgen Insensitivity Syndrome -- Angelman Syndrome -- Apert Syndrome -- Aplasia Cutis Congenita -- Arthrogryposis Multiplex Congenita -- Asphyxiating Thoracic Dystrophy -- Ataxia-Telangiectasia -- Atelosteogenesis -- Autism -- Bannayan-Riley-Ruvalcaba Syndrome -- Beckwith-Wiedemann Syndrome -- Behcet Disease -- Biotinidase Deficiency -- Bladder Exstrophy -- Blepharophimosis, Ptosis, and Epicanthus Inversus Syndrome -- Body Stalk Anomaly -- Brachydactyly -- Branchial Cleft Anomalies -- Calcinosis Cutis -- Campomelic Dysplasia -- Carpenter Syndrome -- Cat Eye Syndrome -- Celiac Disease -- Cerebral Palsy -- Cerebro-Costo-Mandibular Syndrome -- Charcot-Marie-Tooth Disease -- CHARGE Syndrome -- Cherubism -- Chiari Malformation -- Chondrodysplasia Punctata -- Chromosome Abnormalities in Pediatric Solid Tumors -- Cleft Lip and/or Cleft Palate -- Cleidocranial Dysplasia -- Cloacal Exstrophy -- Clubfoot -- Collodion Baby -- Congenital Adrenal Hyperplasia -- Congenital Cutis Laxa -- Congenital Cytomegalovirus Infection -- Congenital Generalized Lipodystrophy -- Congenital Hemihyperplasia -- Congenital Hydrocephalus -- Congenital Hypothyroidism -- Congenital Muscular Dystrophy -- Congenital Toxoplasmosis -- Conjoined Twins -- Corpus Callosum Agenesis/Dysgenesis -- Craniometaphyseal Dysplasia -- Cri-Du-Chat Syndrome -- Crouzon Syndrome -- Cutaneous Vasculitis -- Cutis Marmorata Telangiectatica Congenita -- Cystic Fibrosis -- Dandy-Walker Malformation -- De Lange Syndrome -- Del(18p) Syndrome -- Del(22q11.2) Syndrome -- Del(Yq) Syndrome -- Diabetic Embryopathy -- Down Syndrome -- Duncan Syndrome -- Dyschondrosteosis -- Dysmelia -- Dysplasia Epiphysealis Hemimelica -- Dystonia -- Dystrophinopathies -- Ectrodactyly-Ectodermal Dysplasia-Clefting (EEC) Syndrome -- Ehlers-Danlos Syndrome -- Ellis-van Creveld Syndrome -- Enchondromatosis -- Epidermolysis Bullosa -- Epidermolytic Palmoplantar Keratoderma -- Faciogenital (Faciodigitogenital) Dysplasia -- Facioscapulohumeral Muscular Dystrophy -- Familial Adenomatous Polyposis -- Familial Hyperlysinemia -- Familial Mediterranean Fever -- Familial Patella Instability -- Familial Spastic Paraplegia -- Fanconi Anemia -- Feingold Syndrome -- Femoral Hypoplasia - Unusual Facies Syndrome -- Fetal Akinesia Deformation Sequence -- Fetal Alcohol Spectrum Disorders -- Fetal Hydantoin Syndrome -- Fibrodysplasia Ossificans Progressiva -- Fibular Hemimelia -- Finlay-Marks Syndrome -- Floppy Infant -- Fragile X Syndrome -- Fraser Syndrome -- Freeman-Sheldon Syndrome -- Friedreich Ataxia -- Frontonasal Dysplasia -- Galactosemia -- Gastroschisis -- Gaucher Disease -- Generalized Arterial Calcification of Infancy -- Genitopatellar Syndrome -- Giant Congenital Melanocytic Nevi -- Gilbert Syndrome -- Glucose-6-Phosphate Dehydrogenase Deficiency -- Glycogen Storage Disease, Type 2 -- Goldenhar Syndrome -- Gorlin Syndrome -- Greig Cephalopolysyndactyly Syndrome -- Growth Hormone Deficiency -- Hallermann-Streiff Syndrome -- Harlequin Ichthyosis -- Hemangiomas of Infancy -- Hemophilia A -- Hereditary Hearing Loss -- Hereditary -- Hemochromatosis -- Hereditary Multiple Exostoses -- Hereditary Sensory and Autonomic Neuropathies -- Herlyn-Werner-Wunderlich Syndrome -- Holoprosencephaly -- Holt-Oram Syndrome -- Huntington Disease -- Hydranencephaly -- Hydrolethalus Syndrome -- Hydrops Fetalis -- Hyper-IgE Syndrome -- Hypertrophic Cardiomyopathy (HCM) -- Hypochondroplasia -- Hypoglossia-Hypodactylia Syndrome -- Hypohidrotic Ectodermal Dysplasia -- Hypomelanosis of Ito -- Hypophosphatasia -- Hypopituitarism -- I(1p), I(1q) Syndrome -- Idic(Yq) Syndrome -- Incontinentia Pigmenti -- Infantile Myofibromatosis -- Ivemark Syndrome -- Jarcho-Levin Syndrome -- Joubert Syndrome -- Kabuki Syndrome -- Kasabach-Merritt Syndrome -- KID Syndrome -- Klinefelter Syndrome -- Klippel-Feil Syndrome -- Klippel-Trenaunay Syndrome -- Kniest Dysplasia -- Larsen Syndrome -- LEOPARD Syndrome -- Lesch-Nyhan Syndrome -- Lethal Multiple Pterygium Syndrome -- Loeys-Dietz Syndrome -- Lowe Syndrome -- Lymphangiomas and Lymphangiomatosis -- M#xf6;bius Syndrome -- Macrodactyly -- Marfan Syndrome -- McCune-Albright Syndrome -- Meckel-Gruber Syndrome -- Megalencephalic Leukoencephalopathy with Subcortical Cysts -- Menkes Disease -- Metachromatic Leukodystrophy -- Miller-Dieker Syndrome -- Mitochondrial Leber Hereditary Optic Neuropathy -- Mitochondrial Myopathy -- Mowat-Wilson Syndrome -- Mucolipidosis 2 -- Mucolipidosis 3 -- Mucopolysaccharidosis 1 (MPS 1) -- Mucopolysaccharidosis 2 -- Mucopolysaccharidosis 3 -- Mucopolysaccharidosis 4 -- Mucopolysaccharidosis 6 -- Multiple Endocrine Neoplasia Syndromes -- Multiple Epiphyseal Dysplasia -- Multiple Pterygium Syndrome -- Myotonic Dystrophy Type 1 -- Nager Acrofacial Dysostosis -- Nail-Patella Syndrome -- Nasal Obstruction in Neonates and Children -- Neonatal Herpes Simplex Infection -- Nephrogenic Diabetes Insipidus -- Netherton Syndrome -- Neu-Laxova Syndrome -- Neural Tube Defects -- Neurofibromatosis 1 -- Neurofibromatosis 2 -- Niemann-Pick Disease -- Noonan Syndrome -- Oblique Facial Cleft Syndrome -- Oligohydramnios Sequence -- Omphalocele -- Opitz Trigonocephaly (C) Syndrome -- Oral-Facial-Digital Syndrome -- Osteogenesis Imperfecta -- Osteogenesis Imperfecta Ehlers-Danlos Overlap Syndrome -- Osteopetrosis -- Osteopoikilosis -- Otopalatodigital Spectrum Disorders -- Pachyonychia Congenita -- Pallister-Killian Syndrome -- Peutz-Jeghers Syndrome -- Phenylketonuria -- Pierre Robin Sequence -- Polycystic Kidney Disease, Autosomal Dominant Type -- Polycystic Kidney Disease: Autosomal Recessive Type -- Popliteal Pterygium Syndrome -- Prader-Willi Syndrome -- Primary Microcephaly -- Progeria -- Prune Belly Syndrome -- Pseudoachondroplasia -- R(18) Syndrome -- Radioulnar Synostosis -- Retinoid Embryopathy -- Rett Syndrome -- Rickets -- Rigid Spine Syndrome -- Roberts Syndrome -- Robinow Syndrome -- Rubinstein-Taybi Syndrome -- Saethre-Chotzen Syndrome -- Sagittal Craniosynostosis Associated with Chromosome Abnormalities with a Brief Review on Craniosynostosis -- Schizencephaly Schmid Metaphyseal Chondrodysplasia -- Seckel Syndrome -- Severe Combined Immune Deficiency -- Short Rib-Polydactyly Syndromes -- Sickle Cell Disease -- Silver-Russell Syndrome -- Sirenomelia -- Smith-Lemli-Opitz Syndrome -- Smith-Magenis Syndrome -- Sotos Syndrome -- Spinal Muscular Atrophy -- Spondyloepiphyseal Dysplasia -- Stickler Syndrome -- Sturge-Webber Syndrome -- Symphalangism -- Tay-Sachs Disease -- Tetrasomy 9p Syndrome -- Thalassemia -- Thanatophoric Dysplasia -- Thrombocytopenia-Absent Radius Syndrome -- Treacher-Collins Syndrome -- Trimethylaminuria -- Triploidy -- Trismus-Pseudocamptodactyly Syndrome -- Trisomy 13 Syndrome -- Trisomy 18 Syndrome -- Trisomy 8 Mosaicism Syndrome -- Tuberous Sclerosis -- Turner Syndrome -- Twin-Twin Transfusion Syndrome -- Tyrosinemia -- Ulnar-Mammary Syndrome -- Urofacial Syndrome -- VATER (VACTERL) Association -- Von Hippel-Lindau Disease -- Waardenburg Syndrome -- Weill-Marchesani Syndrome -- Williams Syndrome -- Winchester syndrome -- Wolf-Hirschhorn Syndrome -- X-Linked Agammaglobulinemia -- X-Linked Ichthyosis -- XX Male -- XXX Syndrome -- XXXXX Syndrome -- XXXXY Syndrome -- XY Female -- XYY Syndrome.
Format
e-Book
Publication Type
Encyclopedia
Location
Online
Less detail

Auto-Inflammatory Syndromes : Pathophysiology, Diagnosis, and Management

https://libcat.nshealth.ca/en/permalink/provcat44069
Petros Efthimiou, editor. --Cham: Springer , 2019.
Available Online
View e-Book
Location
Online
This book provides an overview of auto-inflammatory syndromes, covering the underlying immune mechanisms that lead to their development, specific disease presentations, and clinical treatment guidelines. The book is divided into two sections, adult and pediatric, with chapters focusing on individuals diseases such as systemic arthritis, hyper-IgD, pap syndrome, idiopathic recurrent pericarditis, and familial Mediterranean fever. Chapters incorporate the most recent advances in disease pathophys…
Available Online
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Other Authors
Efthimiou, Petros
Responsibility
Petros Efthimiou, editor
Place of Publication
Cham
Publisher
Springer
Date of Publication
2019
Physical Description
1 online resource (xix, 322 p.) : 39 illus., 31 illus. in color
ISBN
9783319969299
9783319969282 (Print ed.)
9783319969305 (Print ed.)
Subjects (MeSH)
Autoimmune Diseases
Hereditary Autoinflammatory Diseases
Inflammation - physiopathology
Specialty
Allergy and Immunology
Abstract
This book provides an overview of auto-inflammatory syndromes, covering the underlying immune mechanisms that lead to their development, specific disease presentations, and clinical treatment guidelines. The book is divided into two sections, adult and pediatric, with chapters focusing on individuals diseases such as systemic arthritis, hyper-IgD, pap syndrome, idiopathic recurrent pericarditis, and familial Mediterranean fever. Chapters incorporate the most recent advances in disease pathophysiology and examine the underlying inductive and effector mechanisms and therapies that relate to each auto-inflammatory disorder at the genetic, molecular, cellular, and epidemiologic levels. The book also discusses the research behind auto-inflammatory disorders to offer detailed clinical guidelines regarding diagnostic techniques, treatment plans, and advice on how to best transition pediatric patients into adult treatment. This is an invaluable reference on auto-inflammatory syndromes for clinicians and researchers in pediatric and adult rheumatology and immunology.
Contents
1. Immunology of Auto-inflammatory Syndromes -- Part I. Monogenic Autoinflammatory Diseases -- 2. Mevalonate Kinase Deficiency (MKD)/Hyperimmunoglobulin D Syndrome (HIDS) -- 3. The TNF Receptor-Associated Autoinflammatory Syndrome (TRAPS) -- 4. PAPA Syndrome and the Spectrum of PSTPIP1-Associated Inflammatory Diseases -- 5. Blau Syndrome -- 6. Deficiency of the Interleukin-1 Receptor Antagonist (DIRA) -- 7. Deficiency of the Interleukin-36 Receptor Antagonist (DITRA) and Generalized Pustular Psoriasis -- 8. Cryopyrin-Associated Periodic Syndromes (CAPS) -- 9. Familial Mediterranean Fever -- 10. Type I Interferonopathies: From Pathophysiology to Clinical Expression -- 11. Deficiency of Adenosine Deaminase 2 (DADA2) -- 12. Yao Syndrome -- Part II. Polygenic Autoinflammatory Diseases -- 13. Systemic Juvenile Idiopathic Arthritis -- 14. Macrophage Activation Syndrome (MAS) -- 15. Schnitzler Syndrome -- 16. Periodic Fever, Aphthous Stomatitis, Pharyngitis, and Cervical Adenitis (PFAPA) Syndrome -- 17. Chronic Nonbacterial Osteomyelitis -- 18. Improving the Transition from Pediatric to Adult Care for Adolescents and Young Adults with Autoinflammatory Diseases -- 19. Adult-Onset Still’s Disease - 20. Idiopathic Recurrent Acute Pericarditis -- 21. Adamantiades-Behçet’s Disease -- 22. Amyloidosis.
Format
e-Book
Location
Online
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Basic immunology : functions and disorders of the immune system

https://libcat.nshealth.ca/en/permalink/provcat32088
Abul K. Abbas, Andrew H. Lichtman and Shiv Pillai. (6th ed.) --Philadelphia, PA: Elsevier , c2020.
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Meticulously reviewed and updated for today’s medical students, Basic Immunology, 6th Edition, is a concise text expertly written by the same distinguished author team as the best-selling, comprehensive text, Cellular and Molecular Immunology. This focused, easy-to-understand volume uses full-color illustrations and clinical images, useful tables, and practical features such as Summary Point boxes, end-of-chapter review questions, glossary terms, and clinical cases-all designed to help student…
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Author
Abbas, Abul K
Other Authors
Lichtman, Andrew H
Pillai, Shiv
Responsibility
Abul K. Abbas, Andrew H. Lichtman and Shiv Pillai
Edition
6th ed.
Place of Publication
Philadelphia, PA
Publisher
Elsevier
Date of Publication
c2020
Physical Description
1 online resource, 336 p.
ISBN
9780323549431
Subjects (MeSH)
Hypersensitivity
Immune System - physiology
Immunity
Immunologic Deficiency Syndromes
Subjects (LCSH)
Immunology
Specialty
Allergy and Immunology
Abstract
Meticulously reviewed and updated for today’s medical students, Basic Immunology, 6th Edition, is a concise text expertly written by the same distinguished author team as the best-selling, comprehensive text, Cellular and Molecular Immunology. This focused, easy-to-understand volume uses full-color illustrations and clinical images, useful tables, and practical features such as Summary Point boxes, end-of-chapter review questions, glossary terms, and clinical cases-all designed to help students master this complex topic in the most efficient, effective manner possible.
Access
Registration required for PDF access.
Format
e-Book
Location
Online
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Basic immunology : functions and disorders of the immune system

https://libcat.nshealth.ca/en/permalink/provcat50410
Abbas, Abul. (5th ed.) --Philadelphia, PA: Elsevier , 2016.
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Location
Online
Available Online
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Author
Abbas, Abul
Edition
5th ed.
Place of Publication
Philadelphia, PA
Publisher
Elsevier
Date of Publication
2016
ISBN
9780323390828
Subjects (MeSH)
Hypersensitivity
Immune System - physiology
Immunity
Immunologic Deficiency Syndromes
Notes
Access to this online resource is restricted to IWK Health Centre employees working from inside the hospital network.
Format
e-Book
Location
Online
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Benign Hematologic Disorders in Children : A Clinical Guide

https://libcat.nshealth.ca/en/permalink/provcat46337
Deepak M. Kamat, Melissa Frei-Jones, editors. --Cham: Springer , c2021.
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NEW Springer 2021
Location
Online
This book provides a comprehensive overview of benign hematologic disorders in children. Divided into nine sections, the text reviews common hematologic disorders or conditions that affect children, while providing state-of-the-art information on pathophysiology, diagnosis, treatment, and management strategies. The text begins with a section on hematopoiesis, and the next section covers red blood cell disorders. The following sections provide overviews of platelet disorders, white blood cell di…
Available Online
View e-Book
Other Authors
Kamat, Deepak M.
Frei-Jones, Melissa
Responsibility
Deepak M. Kamat, Melissa Frei-Jones, editors
Place of Publication
Cham
Publisher
Springer
Date of Publication
c2021
Physical Description
1 online resource (xiii, 512 p.)
ISBN
9783030499808
9783030499792 (Print ed.)
9783030499815 (Print ed.)
9783030499822 (Print ed.)
Subjects (MeSH)
Child
Hematologic Diseases
Specialty
Hematology
Pediatrics
Abstract
This book provides a comprehensive overview of benign hematologic disorders in children. Divided into nine sections, the text reviews common hematologic disorders or conditions that affect children, while providing state-of-the-art information on pathophysiology, diagnosis, treatment, and management strategies. The text begins with a section on hematopoiesis, and the next section covers red blood cell disorders. The following sections provide overviews of platelet disorders, white blood cell disorders, and coagulation disorders. The sixth and seventh sections discuss neonatal hematology and bone marrow failure syndrome. The eighth section reviews supportive care, while the final section covers miscellaneous subjects including pediatric vascular anomalies and complement dysregulation syndromes. Written by experts in the field, Benign Hematologic Disorders in Children: A Clinical Guide is a valuable resource for clinicians and practitioners who treat children afflicted with these disorders.
Contents
Part I. Origin of Blood Cells -- Hematopoiesis -- Part II. Red Blood Cell Disorders -- Nutritional Anemias: Iron Deficiency and Megaloblastic Anemia -- Lead Poisoning -- Immune and Non-Immune Hemolytic Anemia -- Sickle Cell Disease -- Thalassemia -- Disorders of RBC Metabolism -- Red blood cell membrane defects -- Part III. Platelet disorders -- Immune Thrombocytopenia -- Inherited and Congenital Thrombocytopenia -- Platelet Disorders -- Thrombocytosis in Children -- Part IV. WBC disorders -- Neutropenia -- Granulocytosis -- Disorders of Granulocyte Functions -- Part V. Coagulation Disorders -- Von Willebrand Disease -- Hemophilia -- Acquired Disorders of Coagulation in Neonates and Children -- Thromboembolism -- Heavy Menstrual Bleeding and Bleeding Disorders in Adolescents: A Primer for the Primary Care Physician -- Part VI. Neonatal Hematology -- Newborn Screening for Hemoglobinopathies -- Neonatal Immune Hemolytic Anemia -- Neonatal Hemostasis Disorders of Bilirubin Metabolism -- Part VII. Bone Marrow Failure Syndrome -- Failure of Erythrocyte Production -- Inherited Bone Marrow Failure Syndromes -- What Pediatricians Need to Know about Acquired Aplastic Anemia -- Part VIII. Supportive Care -- Immunizations in the Child with Sickle Cell Disease -- Transfusion Medicine for Pediatrics -- Management of infections in neutropenic patients -- Part IX. Miscellaneous -- Pediatric Vascular Anomalies: Opportunities in Primary Care -- Complement Dysregulation Syndromes in Children and Adolescents.
Access
NEW Springer 2021
Format
e-Book
Location
Online
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