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Refractive surgery

https://libcat.nshealth.ca/en/permalink/provcat43772
Dimitri T. Azar ; associate editors Ramon C. Ghanem, Suphi Taneri. --Edinburgh, UK: Elsevier , c2020.
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Comprehensive and clinically focused, Refractive Surgery, 3rd Edition, brings you the knowledge and expertise of leading ophthalmology experts and refractive surgeons from around the world. Together they provide practical coverage of the latest advances in this fast-changing field, including improved optics and biomechanics, improved diagnostics, new surgical techniques, and more. Hundreds of high-quality photographs guide you from patient selection to mastery of surgical techniques.
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Author
Azar, Dimitri T.
Responsibility
Dimitri T. Azar ; associate editors Ramon C. Ghanem, Suphi Taneri
Place of Publication
Edinburgh, UK
Publisher
Elsevier
Date of Publication
c2020
Physical Description
1 online resource, 562 p.
ISBN
9780323547697
Subjects (MeSH)
Corneal Surgery, Laser - methods
Ophthalmologic Surgical Procedures - methods
Refractive Surgical Procedures
Specialty
Ophthalmology
Surgical Procedures, Operative
Abstract
Comprehensive and clinically focused, Refractive Surgery, 3rd Edition, brings you the knowledge and expertise of leading ophthalmology experts and refractive surgeons from around the world. Together they provide practical coverage of the latest advances in this fast-changing field, including improved optics and biomechanics, improved diagnostics, new surgical techniques, and more. Hundreds of high-quality photographs guide you from patient selection to mastery of surgical techniques.
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e-Book
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NeuroPsychopharmacotherapy

https://libcat.nshealth.ca/en/permalink/provcat44556
edited by Peter Riederer, Gerd Laux, Benoit Mulsant, Weidong Le, Toshiharu Nagatsu. --Cham: Springer , c2020.
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Riederer, Peter
Laux, Gerd
Mulsant, Benoit
Le, Weidong
Nagatsu, Toshiharu
Responsibility
edited by Peter Riederer, Gerd Laux, Benoit Mulsant, Weidong Le, Toshiharu Nagatsu
Alternate Title
Neuro-psycho-pharmacotherapy
Place of Publication
Cham
Publisher
Springer
Date of Publication
c2020
Physical Description
1 online resource
ISBN
9783319560151
Subjects (MeSH)
Mental Disorders - drug therapy
Nervous System Diseases - drug therapy
Neuropsychology - methods
Psychotropic Drugs - therapeutic use
Specialty
Neurology
Pharmacology
Psychopharmacology
Notes
"Living reference work."
Contents
Cabergoline in the Treatment of Parkinson’s Disease -- Clinical Aspects of the Pharmacology and Biochemistry of Drugs for the Treatment of Motor Symptoms of Parkinson’s Disease -- Course and Duration of Therapy with Parkinsonian Drugs and Withdrawal Syndromes -- Experimental Psychopharmacology -- Historical Overview of Psychiatric Diagnostics in Japan -- Mood Stabilizer: Definition -- Mood Stabilizers: Course and Duration of Therapy, Withdrawal Syndromes, and Resistance to Therapy -- Pergolide in the Treatment of Parkinson’s Disease -- Pharmacology of Alcohol and Alcohol Use Disorder -- Randomized Controlled Trials and the Efficacy of Psychotropic Medications -- Side Effects, Contraindications, and Drug-Drug Interactions in the Use of Antiparkinsonian Drugs.
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e-Book
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Make Life Visible

https://libcat.nshealth.ca/en/permalink/provcat44715
Yoshiaki Toyama, Atsushi Miyawaki, Masaya Nakamura, Masahiro Jinzaki, editors. --Singapore: SpringerOpen , c2020.
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This open access book describes marked advances in imaging technology that have enabled the visualization of phenomena in ways formerly believed to be completely impossible. These technologies have made major contributions to the elucidation of the pathology of diseases as well as to their diagnosis and therapy. The volume presents various studies from molecular imaging to clinical imaging. It also focuses on innovative, creative, advanced research that gives full play to imaging technology in …
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Toyama, Yoshiaki
Miyawaki, Atsushi
Nakamura, Masaya
Jinzaki, Masahiro
Responsibility
Yoshiaki Toyama, Atsushi Miyawaki, Masaya Nakamura, Masahiro Jinzaki, editors
Place of Publication
Singapore
Publisher
SpringerOpen
Date of Publication
c2020
Physical Description
1 online resource (ix, 292 p.) : 137 illus., 106 illus. in color
ISBN
9789811379086
9789811379079 (Print ed.)
9789811379093 (Print ed.)
9789811379109 (Print ed.)
Subjects (MeSH)
Biomedical Technology
Clinical Laboratory Techniques
Diagnostic Imaging - methods
Image Processing, Computer-Assisted - methods
Subjects (LCSH)
Neurosciences
Immunology
Cell biology
Specialty
Diagnostic Imaging
Abstract
This open access book describes marked advances in imaging technology that have enabled the visualization of phenomena in ways formerly believed to be completely impossible. These technologies have made major contributions to the elucidation of the pathology of diseases as well as to their diagnosis and therapy. The volume presents various studies from molecular imaging to clinical imaging. It also focuses on innovative, creative, advanced research that gives full play to imaging technology in the broad sense, while exploring cross-disciplinary areas in which individual research fields interact and pursuing the development of new techniques where they fuse together. The book is separated into three parts, the first of which addresses the topic of visualizing and controlling molecules for life. Th e second part is devoted to imaging of disease mechanisms, while the final part comprises studies on the application of imaging technologies to diagnosis and therapy. The book contains the proceedings of the 12th Uehara International Symposium 2017, “Make Life Visible” sponsored by the Uehara Memorial Foundation and held from June 12 to 14, 2017. It is written by leading scientists in the field and is an open access publication under a CC BY 4.0 license.
Contents
Part 1: Visualizing and Controlling Molecules for Life -- 1. Photoacoustic Tomography: Deep Tissue Imaging by Ultrasonically Beating Optical Diffusion -- 2. Regulatory Mechanism of Neural Stem Cells Revealed by Optical Manipulation of Gene Expressions -- 3. Eavesdropping on Biological Processes with Multi-Dimensional Molecular Imaging -- 4. Apical microtubules define the function of epithelial cell sheets consisting of non-ciliated or multi-ciliated cells -- 5. Illuminating the brain -- 6. Optogenetic assemblies of cortical force-generating complexes during mitosis -- 7. In vivo Imaging Probes with Tunable Chemical Switches -- 8. Circuit-dependent striatal PKA and ERK signaling underlying action selection -- 9. Electrophysiology, Unplugged: New Chemical Tools to Image Voltage -- 10. Molecular dynamics revealed by single-molecule FRET measurement -- 11. Comprehensive approaches using luminescence to studies of cellular functions -- Part II: Imaging Disease Mechanisms -- 12. Make Chronic Pain Visible -- 13. Cortical plasticity after spinal cord injury using resting-state functional magnetic resonance imaging -- 14. Multimodal Label-free imaging to assess compositional and morphological changes in cells during immune activation -- 15. Investigating in vivo myocardial and coronary molecular pathophysiology in mice with X-ray radiation imaging approaches -- 16. Visualizing the Immune Response to Infections -- 17. Imaging Sleep and Wakefulness -- 18. Abnormal local translation in dendrites impairs cognitive functions in neuropsychiatric disorders -- 19. Imaging synapse formation and remodeling in vitro and in vivo -- Part III: Imaging-based Diagnosis and Therapy -- 20. How MRI makes the Brain Visible -- 21. Intravital multiphoton imaging revealing cellular dynamics in vivo -- 22. Theranostic Near Infrared Photoimmunotherapy for Cancer -- 23. Novel and integrated imaging on Chronic Fatigue -- 24. Novel fluorescent probes for rapid tumor imaging and fast glutathione dynamics -- 25. Coronary Heart Disease Diagnosis: Engineering Triumphs, Economic Barriers -- 26. Live imaging of the skin immune responses -- 27. Development of a horizontal CT and its application to musculoskeletal disease -- 28. The Future of Precision Health & Integrated Diagnostics -- 29. Imaging and therapy against hypoxic tumors with 64Cu-ATSM.
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Open access
Format
e-Book
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Clostridium Difficile Infection in Long-Term Care Facilities : A Clinician's Guide

https://libcat.nshealth.ca/en/permalink/provcat44808
Teena Chopra, editor. --Cham: Springer , c2020.
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This book aims to fill knowledge gap among healthcare workers about Clostridium difficile (also known as C.difficile and CDI) among aging patients, especially those in long-term care facilities (LTCFs). Written by experts in infectious diseases and geriatric medicine, this book provides comprehensive information on all aspects of CDI pertaining to LTCF settings, including epidemiology, diagnosis, prevention, management and the unique challenges faced by LTCFs with regards to the CDI problem. Th…
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Other Authors
Chopra, Teena
Responsibility
Teena Chopra, editor
Place of Publication
Cham
Publisher
Springer
Date of Publication
c2020
Physical Description
1 online resource (viii, 80 p.) : 1 illus. in color
ISBN
9783030297725
9783030297718 (Print ed.)
9783030297732 (Print ed.)
Subjects (MeSH)
Clostridium Difficile
Clostridium Infections - prevention & control
Infection Control
Long-Term Care
Specialty
Communicable Disease Control
Infectious Disease Medicine
Abstract
This book aims to fill knowledge gap among healthcare workers about Clostridium difficile (also known as C.difficile and CDI) among aging patients, especially those in long-term care facilities (LTCFs). Written by experts in infectious diseases and geriatric medicine, this book provides comprehensive information on all aspects of CDI pertaining to LTCF settings, including epidemiology, diagnosis, prevention, management and the unique challenges faced by LTCFs with regards to the CDI problem. The book begins by introducing the topic as it relates to aging patients before delving into the various aspects of CDI management. Topics include infection control and prevention, treatment of CDI, and the establishment of antibiotic stewardship programs to reduce inappropriate antibiotic use and reduce CDI rates. The book also features a chapter on probiotics for the prevention of CDI and new strategies to monitor environmental cleaning practices of CDI patient rooms that do not appear in any other resource. Clostridium Difficile Infection in Long-Term Care Facilities is an excellent resource for geriatricians, infectious diseases specialists, long-term care administrators, nurses, pharmacists, researchers, and all clinicians working with infections in long-term care settings.
Contents
1. Introduction -- 2. Epidemiology of Clostridioides difficile Infection in Long-Term Care Facilities -- 3. Role of Asymptomatic Carriers in Long-Term Care Facility Clostridioides (Clostridium) difficile Transmission -- 4. Clostridium difficile (Clostridioides difficile) Infection Surveillance in Long-Term Care Facilities -- 5. Clostridium difficile Diagnostics in Long-Term Care Facilities -- 6. Control of Clostridium (Clostridioides) difficile Infection in Long-Term Care Facilities/Nursing Homes -- 7. Antibiotic Stewardship Related to CDI in Long-Term Care Facilities.
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e-Book
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Precision in Pulmonary, Critical Care, and Sleep Medicine : A Clinical and Research Guide

https://libcat.nshealth.ca/en/permalink/provcat44843
Jose L. Gomez, Blanca E. Himes, Naftali Kaminski, editors. --Cham: Humana Press , c2020.
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This book serves as the primary reference for precision medicine in the fields of pulmonary, critical care and sleep medicine by documenting principles written by experts in several aspects of precision medicine. It combines fundamental concepts of the field with state-of-the-art studies and how they translate into individual preventive, diagnostic and therapeutic plans. Precision medicine is focused on the integration of individual variability with disease prevention and treatment principles d…
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Other Authors
Gomez, Jose L.
Himes, Blanca E.
Kaminski, Naftali
Responsibility
Jose L. Gomez, Blanca E. Himes, Naftali Kaminski, editors
Place of Publication
Cham
Publisher
Humana Press
Date of Publication
c2020
Physical Description
1 online resource (xv, 441 p.) : 71 illus., 63 illus. in color
Series Title
Respiratory medicine
ISBN
9783030315078
9783030315061 (Print ed.)
9783030315085 (Print ed.)
9783030315092 (Print ed.)
ISSN
2197-7372
Subjects (MeSH)
Critical Care
Precision Medicine
Pulmonary Medicine
Sleep Medicine Specialty
Specialty
Critical Care
Precision Medicine
Pulmonary Medicine
Sleep Medicine Specialty
Abstract
This book serves as the primary reference for precision medicine in the fields of pulmonary, critical care and sleep medicine by documenting principles written by experts in several aspects of precision medicine. It combines fundamental concepts of the field with state-of-the-art studies and how they translate into individual preventive, diagnostic and therapeutic plans. Precision medicine is focused on the integration of individual variability with disease prevention and treatment principles derived from population studies. This concept has risen to prominence in recent years in parallel with advances in genetics, molecular diagnostics and novel target-specific therapies. This fundamental shift in the approach to treatment has broad implications in how we prevent, diagnose and treat disease. Describing key concepts of precision medicine and relating these to pulmonary, critical care and sleep disorders is essential to educate relevant stakeholders and increase the impact of pulmonary precision medicine. The book is organized into seven sections: introduction; genetics; biomarkers; precise phenotyping; mobile health, wearables and telemedicine; precision therapeutics; enabling widespread adoption of precision medicine. The chapters are organized with an introduction to the specific theme, followed by its basic concepts. They then delve into how these basic concepts relate to the larger theme of precision medicine, new precision medicine approaches to dealing with these problems, and key takeaway points. Liberally illustrated with images, figures, and tables, the text is thorough and intuitive for clinicians and researchers to learn the processes and applications of precision medicine. This is an ideal guide for clinicians to learn new precision medicine concepts in the fields of genetics, genomics, mobile health, and how they apply to their practice and their patients, as well as researchers seeking a basic understanding of precision medicine to assist in designing future research studies.
Contents
Part I. Introduction -- Introduction -- Part II. Genetics -- Differential Diagnosis of Diffuse Pulmonary Disorders Using Genetics -- Genetics and Pharmacogenetics of Asthma -- Genetics and Pharmacogenetics of COPD -- The Evolution of Precision Medicine in Cystic Fibrosis -- Genetics of Idiopathic Pulmonary Fibrosis -- Genetics of Lung Cancer -- Part III. Biomarkers -- Chest Imaging for Precision Medicine -- Biobanking for Pulmonary, Critical Care, and Sleep Medicine -- Biomarkers in Obstructive Airway Diseases -- Biomarkers in Interstitial Lung Diseases -- Molecular Diagnostics in Pulmonary Infections -- Biomarkers in Critical Care Illness: ARDS and Sepsis -- Part IV. Precise Phenotyping -- Lessons for Precision Medicine from Lung Cancer -- COPD Phenotyping -- Precision Medicine in Pulmonary Hypertension -- Identifying Subtypes of Obstructive Sleep Apnea -- Precision Medicine in Critical Illness: Sepsis and Acute Respiratory Distress Syndrome -- Part V. Mobile Health, Wearables, and Telemedicine -- Mobile Applications and Wearables for Chronic Respiratory Diseases Monitoring -- Personal Environmental Monitoring -- Tele-ICU in Precision Medicine: It’s Not What You Do It’s How You Do It -- Part VI. Precision Therapeutics -- Lung Transplantation and Precision Medicine -- Precision in Mechanical Ventilation -- Precision Medicine for Cigarette Smoking Addiction -- Implementing COPD Precision Medicine in Clinical Practice -- Part VII. Enabling Widespread Adoption of Precision Medicine -- Precision Medicine For All: Minority Health -- Education for the Practice of Precision Medicine in PCCSM: Creating Tomorrow’s Workforce -- Summary and Future Applications of Precision Medicine in Pulmonary, Critical Care and Sleep Medicine.
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e-Book
Location
Online
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Retinal Pigment Epithelium in Health and Disease

https://libcat.nshealth.ca/en/permalink/provcat44876
Alexa Karina Klettner, Stefan Dithmar, editors. --Cham: Springer , c2020.
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This book provides a contemporary resource on one of the major players in retinal diseases – the Retinal Pigment Epithelium (RPE). Throughout the book, the physiological and the pathological function of the RPE are covered on equal terms, to help readers to understand the RPE as a whole. Moreover, the development of RPE in diagnostics and therapy are covered, as well as some practical knowledge about RPE experimental models. Retinal Pigment Epithelium in Health and Disease highlights new findin…
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Other Authors
Klettner, Alexa Karina
Dithmar, Stefan
Responsibility
Alexa Karina Klettner, Stefan Dithmar, editors
Place of Publication
Cham
Publisher
Springer
Date of Publication
c2020
Physical Description
1 online resource (xi, 357 p.) : 117 illus., 100 illus. in color
ISBN
9783030283841
9783030283834 (Print ed.)
9783030283858 (Print ed.)
9783030283865 (Print ed.)
Subjects (MeSH)
Models, Biological
Retinal Diseases - etiology
Retinal Pigment Epithelium - physiopathology
Specialty
Ophthalmology
Abstract
This book provides a contemporary resource on one of the major players in retinal diseases – the Retinal Pigment Epithelium (RPE). Throughout the book, the physiological and the pathological function of the RPE are covered on equal terms, to help readers to understand the RPE as a whole. Moreover, the development of RPE in diagnostics and therapy are covered, as well as some practical knowledge about RPE experimental models. Retinal Pigment Epithelium in Health and Disease highlights new findings of RPE research and includes the state-of-the-art knowledge of each RPE topic presented. This important feature sets this book apart from other publications, with the chapters following a design which leads from the general to the specific, to give a precise collection of the facts known. The chapters are written by well-known experts that are currently active in the field as consultants, basic scientists, and group leaders, providing expert guidance on the current aspects and future outlooks of this topic.
Contents
Part I. Physiological RPE function -- 1. RPE Histopathology and Morphometry -- 2. RPE Polarity and Barrier Functions -- 3. RPE Phagocytosis -- 4. Ion Channels of the Retinal Pigment Epithelium -- 5. RPE and the Vascular Endothelial Growth Factor -- 6. The RPE cell and the Immune system -- Part II.The RPE in Disease -- 7. The RPE in Myopia development -- 8. Retinal Pigment Epithelium in Proliferative Disorders -- 9. Retinal pigment epithelium in health and disease: maturation, aging and age-related macular degeneration -- 10. Retinal Pigment Epithelium in Age-related Macular Degeneration -- 11. Sex Related Differences in Retinal Pigment Epithelium and Retinal Disease -- Part III. The RPE in Diagnostics -- 12. RPE in Optical Coherence Tomography -- 13. RPE Autofluorescence -- Part IV. The RPE in Therapy -- 14. RPE and Stem Cell Therapy -- 15. RPE in Gene Therapy -- 16. RPE and Laser -- Part V. Experimental RPE Models -- 17. RPE Cell Culture -- 18. Retinal Pigment Epithelium Organ Culture -- 19. Animal Models of Diseases of the Retinal Pigment Epithelium.
Format
e-Book
Location
Online
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Highly Infectious Diseases in Critical Care : A Comprehensive Clinical Guide

https://libcat.nshealth.ca/en/permalink/provcat44893
Jorge Hidalgo, Laila Woc-Colburn, editos. --Cham: Springer , c2020.
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This book provides a comprehensive overview of highly infectious diseases (HIDs) in the ICU. The text is designed to help critical care specialists and other healthcare practitioners prepare and plan for potential outbreaks of emerging or resurgent HIDs, lead a team in the ICU, perform emergency triage, and provide care for patients with a HID. The book also reviews some of the most prevalent highly infectious diseases, including influenza, SARS, plague, anthrax, and malaria. Written by experts…
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Other Authors
Hidalgo, Jorge
Woc-Colburn, Laila
Responsibility
Jorge Hidalgo, Laila Woc-Colburn, editos
Place of Publication
Cham
Publisher
Springer
Date of Publication
c2020
Physical Description
1 online resource (xv, 276 p.) : 43 illus., 32 illus. in color
ISBN
9783030338039
9783030338022 (Print ed.)
9783030338046 (Print ed.)
9783030338053 (Print ed.)
Subjects (MeSH)
Communicable Diseases - prevention & control
Communicable Diseases - transmission
Critical Care - methods
Infection Control - methods
Intensive Care Units - standards
Specialty
Communicable Disease Control
Critical Care
Infectious Disease Medicine
Abstract
This book provides a comprehensive overview of highly infectious diseases (HIDs) in the ICU. The text is designed to help critical care specialists and other healthcare practitioners prepare and plan for potential outbreaks of emerging or resurgent HIDs, lead a team in the ICU, perform emergency triage, and provide care for patients with a HID. The book also reviews some of the most prevalent highly infectious diseases, including influenza, SARS, plague, anthrax, and malaria. Written by experts in the field, Highly Infectious Diseases in Critical Care: A Comprehensive Clinical Guide is a valuable resource for critical care and infectious disease specialists who treat patients afflicted with a highly infectious disease in the ICU.
Contents
How Infectious Diseases Have Influenced our Culture -- Evolution and Globalization of Antimicrobial Resistance -- Emergency Triage of Highly Infectious Diseases and Bioterrorism -- Diagnostics: The Role of the Laboratory -- Influenza, Measles, SARS, MERS, and Smallpox -- Zoonotic Infections and Biowarfare Agents in Critical Care: Anthrax, Plague, and Tularemia -- Hemorrhagic Fevers -- Multidrug Resistance Bacterial Infection -- Central Nervous System Infection -- Intracranial Pressure Monitoring and Management in Bacterial Meningitis -- Rabies -- Tetanus -- Malaria -- Tuberculosis Multidrug Resistance (MDR-TB) -- Preparing the ICU for a Highly Infectious Disease -- Pandemic Declaration and Preparation.
Format
e-Book
Location
Online
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Biomarkers in Periodontal Health and Disease : Rationale, Benefits, and Future Directions

https://libcat.nshealth.ca/en/permalink/provcat44899
Nurcan Buduneli. --Cham: Springer , c2020.
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This book examines all aspects of the progress being made towards the development of highly specific and sensitive biomarkers that will overcome the shortcomings of clinical assessments in periodontics. The opening chapters present the basic anatomic features of periodontal tissues, outline the nature and pathogenic mechanisms of periodontal diseases, and discuss both conventional and novel methods of diagnosis with reference to their specificity and sensitivity. The potential role of biomarker…
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Author
Buduneli, Nurcan
Responsibility
Nurcan Buduneli
Place of Publication
Cham
Publisher
Springer
Date of Publication
c2020
Physical Description
1 online resource (xv, 90 p.) : 34 illus., 33 illus. in color
ISBN
9783030373177
9783030373153 (Print ed.)
9783030373160 (Print ed.)
Subjects (MeSH)
Biomarkers
Periodontal Diseases - diagnosis
Specialty
Dentistry
Diagnosis
Oral Health
Abstract
This book examines all aspects of the progress being made towards the development of highly specific and sensitive biomarkers that will overcome the shortcomings of clinical assessments in periodontics. The opening chapters present the basic anatomic features of periodontal tissues, outline the nature and pathogenic mechanisms of periodontal diseases, and discuss both conventional and novel methods of diagnosis with reference to their specificity and sensitivity. The potential role of biomarkers in periodontal diagnosis is then presented in the light of the published data. The biological samples in which potential biomarkers are sought are evaluated comparatively, drawing attention to their strengths and weaknesses, and the available technologies for biomarker studies are reviewed. The potential benefits of biomarkers are also discussed with regard to the possible bidirectional interactions between periodontal diseases and systemic health. Finally, the past, present, and future of periodontics are examined from a broader perspective. Readers will find the book to be an ideal summary of the state of the art in the field as biomarkers emerge that promise to facilitate periodontal diagnostics and permit timely, personally tailored interventions.
Contents
1. Anatomy of Periodontal Tissues -- 2. Nature of Periodontal Diseases -- 3. Conventional Diagnosis of Periodontal Diseases and 2017 Classification System -- 4. Novel Diagnostic Approaches in Periodontics -- 5. Biomarkers for Periodontal Diseases -- 6. Biological Samples for Biomarkers: Strengths and Weaknesses -- 7. Technologies for Biomarkers in Periodontics -- 8. Biomarkers in Periodontal Disease and Systemic Health Intersection -- 9. Past, Present and Future of Periodontics.
Format
e-Book
Location
Online
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Practical Cytopathology : Frequently Asked Questions

https://libcat.nshealth.ca/en/permalink/provcat44954
Huihong Xu, Xiaohua Qian, He Wang, editors. --Cham: Springer , c2020.
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This book provides a comprehensive, practical, and state-of-the art review addressing the major issues and challenges in cytopathology practice using a question and answer format. Making an accurate diagnosis, especially on a limited cytology sample obtained by minimally invasive procedures, is often challenging, yet crucial to patient care. Using the most current and evidence-based approaches, this book: 1) focuses on frequently asked questions in day-to-day practice of cytopathology as well a…
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Other Authors
Xu, Huihong
Qian, Xiaohua
Wang, He
Responsibility
Huihong Xu, Xiaohua Qian, He Wang, editors
Place of Publication
Cham
Publisher
Springer
Date of Publication
c2020
Physical Description
1 online resource (xii, 346 p.) : 323 illus. in color
Series Title
Practical anatomic pathology
ISBN
9783030240592
9783030240585 (Print ed.)
9783030240608 (Print ed.)
9783030240615 (Print ed.)
Subjects (MeSH)
Cells - pathology
Cytodiagnosis
Specialty
Cell Biology
Pathology
Abstract
This book provides a comprehensive, practical, and state-of-the art review addressing the major issues and challenges in cytopathology practice using a question and answer format. Making an accurate diagnosis, especially on a limited cytology sample obtained by minimally invasive procedures, is often challenging, yet crucial to patient care. Using the most current and evidence-based approaches, this book: 1) focuses on frequently asked questions in day-to-day practice of cytopathology as well as surgical pathology; 2) provides quick, accurate, and useful answers; 3) emphasizes the importance of clinical, radiological, and cytological correlation, as well as cyto-histological correlation; and 4) delineates how to judiciously use immunohistochemistry, molecular tests, flow cytometry, cytogenetics, and other established ancillary studies including next generation sequencing and computer-assisted diagnostics. Chapters are written by experts in their fields and provide the most up-to-date information in the field of cytopathology. Practical Cytopathology: Frequently Asked Questions serves as a practical resource and guide to relevant references for trainees, cytotechnologists, and cytopathologists at various skill levels.
Contents
Cytology Techniques -- Cytopathology Laboratory Management -- Overview of Cervical and Anal Cytopathology -- Normal and Benign Cervical Cytology -- Cervical Cytology with Squamous and Glandular Abnormalities -- Gastrointestinal, Pancreas and Bile Ducts Cytology -- Lung and Respiratory Tract Cytology -- Urine Cytology -- Body Cavity Effusions and Washings -- Cerebrospinal Fluid -- Ovary and Peritoneal Washings -- Fine Needle Aspiration Cytology of the Breast -- Thyroid -- Salivary Gland -- Lymph Nodes -- Liver Cytopathology -- Soft Tissue and Bone -- Kidney, Adrenal Gland, and Retroperitoneum -- Ocular Cytology.
Format
e-Book
Location
Online
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Genomic Medicine : A Practical Guide

https://libcat.nshealth.ca/en/permalink/provcat44958
Laura J. Tafe, Maria E. Arcila, editors. --Cham: Springer , c2020.
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The field of Molecular Diagnostics is rapidly evolving and molecular characterization of neoplasms is becoming an increasingly important part of the pathologic work up and diagnosis of many tumor types. This work provides a high-yield reference book that compiles critical information related to molecular biomarkers for various solid tumor and hematologic malignancy subtypes. It is succinct yet comprehensive enough to be suitable for fellows in training and medical professionals with an interest…
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Other Authors
Tafe, Laura J.
Arcila, Maria E.
Responsibility
Laura J. Tafe, Maria E. Arcila, editors
Place of Publication
Cham
Publisher
Springer
Date of Publication
c2020
Physical Description
1 online resource (x, 325 p.) : 21 illus., 20 illus. in color
ISBN
9783030229221
9783030229214 (Print ed.)
9783030229238 (Print ed.)
Subjects (MeSH)
Biomarkers, Tumor
Molecular Diagnostic Techniques
Pathology, Molecular
Precision Medicine - methods
Specialty
Genetics, Medical
Abstract
The field of Molecular Diagnostics is rapidly evolving and molecular characterization of neoplasms is becoming an increasingly important part of the pathologic work up and diagnosis of many tumor types. This work provides a high-yield reference book that compiles critical information related to molecular biomarkers for various solid tumor and hematologic malignancy subtypes. It is succinct yet comprehensive enough to be suitable for fellows in training and medical professionals with an interest in molecular pathology and biomarkers. The book covers many aspects of molecular diagnostics, from techniques to applications and comprehensive summaries of the current molecular biomarkers of critical importance in solid and liquid tumors. Attention is also specifi cally devoted to bioinformatics and next generation sequencing, as well as pre-analytical issues that must be considered for accurate interpretation of molecular results in the context of overall patient care. This text focuses on clinical utility and validity and serves as an “owner’s manual” in Genomic Diagnostics for the practicing pathologist, pathology fellows and residents and other health care providers. Physicians will find this book invaluable as a quick reference for current molecular testing modalities and guidelines, tumor board preparation, deciding which test to order and interpreting genomic laboratory results. In addition, it is an accessible for trainees as a board review preparation reference.
Contents
Part I. General Concepts -- Pre-Analytics, Current Testing Technologies, and Limitations of Testing -- Next Generation Sequencing -- Cell-Free DNA Testing -- Role of Bioinformatics in Molecular Medicine -- Interpreting Genomic Reports -- Part II. Applications in Solid Tumors -- Lung Carcinoma -- GI including GIST -- Breast -- Genitourinary Tumors -- Gynecologic Malignancies -- Sarcomas -- Salivary Gland Carcinomas -- Sinonasal Carcinomas -- Part III. Applications in Hematopathology -- Acute Myeloid Neoplasms -- Chronic Myeloid Neoplasms -- Lymphomas.
Format
e-Book
Location
Online
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WSES Handbook of Mass Casualties Incidents Management

https://libcat.nshealth.ca/en/permalink/provcat45067
Yoram Kluger, Federico Coccolini, Fausto Catena, Luca Ansaloni, editors. --Cham: Springer , c2020.
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This manual, written by world opinion leaders in the field, is designed to provide readily accessible, step-by-step guidance on all aspects of the management of mass casualty incidents. Readers will find a wealth of helpful practical suggestions as well as information on the latest relevant scientific advances and their implications. Globally, mass casualty incidents are becoming more frequent even in unexpected places. There is a need for a dependable manual suitable for use by all who must be…
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Other Authors
Kluger, Yoram
Coccolini, Federico
Catena, Fausto
Ansaloni, Luca
Other Authors
World Society of Emergency Surgery
Responsibility
Yoram Kluger, Federico Coccolini, Fausto Catena, Luca Ansaloni, editors
Place of Publication
Cham
Publisher
Springer
Date of Publication
c2020
Physical Description
1 online resource (x, 202 p.) : 50 illus., 35 illus. in color
Series Title
Hot topics in acute care surgery and trauma
ISBN
9783319923451
9783319923444 (Print ed.)
9783319923468 (Print ed.)
ISSN
2520-8284
Subjects (MeSH)
Disaster Planning
Emergency Service, Hospital
Disaster Medicine - organization & administration
Mass Casualty Incidents
Specialty
Disaster Medicine
Abstract
This manual, written by world opinion leaders in the field, is designed to provide readily accessible, step-by-step guidance on all aspects of the management of mass casualty incidents. Readers will find a wealth of helpful practical suggestions as well as information on the latest relevant scientific advances and their implications. Globally, mass casualty incidents are becoming more frequent even in unexpected places. There is a need for a dependable manual suitable for use by all who must be prepared to face mass casualty incidents, including practicing physicians, surgeons, anesthesiologists, nurses, and administrators. This book meets that need. It is the first practical manual to be devoted to the topic, and its portable format will allow it to be kept in the pocket at all times, ready for immediate consultation. The innovative nature of much of the content and the inclusion of up-to-date literature reviews ensure that the manual will remain relevant for years to come.
Contents
1. Mass Casualty Incident: Definitions and Current Reality -- 2. Managing a Medical Surge -- 3. Common Wounding Mechanisms and Injury Patterns -- 4. The Emergency Room During Mass Casualty Incidents -- 5. Triage and Clinical Evaluation in MCI -- 6. Providing Information During Mass Casualty Incidents: Information Center, Family-Centered Care and Media Coverage -- 7. Nurses and Nursing in Mass Casualties Incidents -- 8. Auxiliary Clinical Diagnostics -- 9. Conventional and Interventional Radiology in Mass Casualty Incidents -- 10. Operating Room (OR) Setup, Resource, and Demands -- 11. Intensive Care Unit (ICU): Resources and Demands -- 12. The Pediatric Patient in MCI -- 13. Definitive Care Phase of a Mass Casualty Incident -- 14. Preparedness to Non-conventional Incidents in the Civilian Medical Arena -- 15. Mass Casualties Management in Low-Income Countries -- 16. Mass Casualties Incident: Education, Simulation, and Training -- 17. Debriefing Session: The Process of Self-Evaluation -- 18. Ethics in Mass Casualty Incidents.
Format
e-Book
Publication Type
Handbook
Location
Online
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Management of Non-Muscle Invasive Bladder Cancer

https://libcat.nshealth.ca/en/permalink/provcat45092
Sanchia S. Goonewardene, Raj Persad, Hanif Motiwala, David Albala. --Cham: Springer , c2020.
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Location
Online
This book covers the latest advances in non-muscle invasive bladder cancer care. It provides a review of the available evidence base for the efficacy of a range of therapeutic techniques, diagnostic procedures and risk factors. Management of Non-Muscle Invasive Bladder Cancer features detailed guidance in uniformly formatted chapters on how to properly apply a range of available therapeutic treatments relevant for patient care. It is a valuable resource for all trainee and practising medical pr…
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Author
Goonewardene, Sanchia S.
Other Authors
Persad, Raj
Motiwala, Hanif
Albala, David
Responsibility
Sanchia S. Goonewardene, Raj Persad, Hanif Motiwala, David Albala
Place of Publication
Cham
Publisher
Springer
Date of Publication
c2020
Physical Description
1 online resource (xxiv, 402 p.) : 20 illus., 19 illus. in color
ISBN
9783030286460
9783030286453 (Print ed.)
9783030286477 (Print ed.)
9783030286484 (Print ed.)
Subjects (MeSH)
Survivorship
Treatment Outcome
Urinary Bladder Neoplasms - diagnosis
Urinary Bladder Neoplasms - pathology
Urinary Bladder Neoplasms - therapy
Specialty
Medical Oncology
Urology
Abstract
This book covers the latest advances in non-muscle invasive bladder cancer care. It provides a review of the available evidence base for the efficacy of a range of therapeutic techniques, diagnostic procedures and risk factors. Management of Non-Muscle Invasive Bladder Cancer features detailed guidance in uniformly formatted chapters on how to properly apply a range of available therapeutic treatments relevant for patient care. It is a valuable resource for all trainee and practising medical professionals who treat these patients.
Contents
Part I. Background and Pathology on Bladder Cancer -- Part II. Histological Variants in Bladder Cancer -- Part III. Epidemiology and Risk Factors in Bladder Cancer -- Part IV. Assessment and Diagnostics in NMIBC -- Part V. Techniques in Endoscopic Resection -- Part VI. Management of Low and Intermediate Risk Bladder Cancer -- Part VII. Management of High Risk Non-Muscle Invasive Bladder Cancer -- Part VIII. Bladder Cancer in the Elderly and Females -- Part IX. Bladder Cancer Survivorship
Format
e-Book
Location
Online
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Rapid On-Site Evaluation (ROSE) in Diagnostic Interventional Pulmonology : Volume 4, Metagenomic Sequencing Application in Difficult Cases of Infectious Diseases

https://libcat.nshealth.ca/en/permalink/provcat45272
Jing Feng, Bo Wu, Erlie Jiang, Wen Li, Chen Meng, editors. --Singapore: Springer , c2020.
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Location
Online
This book covers up-to-date evidence of Rapid on-site evaluation (ROSE) for diagnosis of rare disease and used combined with metagenomic sequencing technique in clinical scenarios. ROSE has becoming an efficient interventional diagnostics tool and important reference for lung diseases differentiation, increasing the adequacy rate, diagnostic yield and accuracy of the interventional pulmonary procedures. ROSE has its value in the field of evaluating sampling adequacy for further immunohistochemi…
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Other Authors
Feng, Jing
Wu, Bo
Jiang, Erlie
Li, Wen
Meng, Chen
Responsibility
Jing Feng, Bo Wu, Erlie Jiang, Wen Li, Chen Meng, editors
Alternate Title
ROSE in diagnostic interventional pulmonology
Place of Publication
Singapore
Publisher
Springer
Date of Publication
c2020
Physical Description
1 online resource (vii, 376 p.) : 366 illus., 202 illus. in color
ISBN
9789811552465
9789811552458 (Print ed.)
9789811552472 (Print ed.)
9789811552489 (Print ed.)
Subjects (MeSH)
Cytodiagnosis - methods
Respiratory Tract Infections - diagnosis
Respiratory Tract Infections - genetics
Specialty
Genetics, Medical
Infectious Disease Medicine
Pulmonary Medicine
Abstract
This book covers up-to-date evidence of Rapid on-site evaluation (ROSE) for diagnosis of rare disease and used combined with metagenomic sequencing technique in clinical scenarios. ROSE has becoming an efficient interventional diagnostics tool and important reference for lung diseases differentiation, increasing the adequacy rate, diagnostic yield and accuracy of the interventional pulmonary procedures. ROSE has its value in the field of evaluating sampling adequacy for further immunohistochemistry, microbiology studies, flow cytometry analysis, and molecular assays; DNA analysis of biopsy specimens using sequencing technique is performed to provide clue of etiology, which is an emerging pathway for clinical dilemmas. The first part of the book discusses the principals of performing ROSE procedures and reviews the basic concepts and summarized knowledge of key anatomical structures in lung. Figures of ROSE cytopathology, together with clinical data, results of metagenomic sequencing technique are presented to demonstrate how the difficulties in clinical practice could be tackled with the help of advanced techniques. Further application direction and perspective are also discussed, which provides researchers with more insights on the discipline and techniques. This book is part of the 4-volume collection ROSE in Diagnostic Interventional Pulmonology.
Contents
1. Tuberculosis -- 2. Non-tuberculous Mycobacterium Infections -- 3. Bacterial Pneumonia -- 4. Viral Pneumonia -- 5. Pulmonary Cryptococcosis -- 6. Pneumocystis jirovecii Pneumonia -- 7. Pulmonary Aspergillosis -- 8. Pulmonary Mucormycosis -- 9. Other Mycotic Pneumonia -- 10. Pulmonary Mixed Infections -- 11. Other Pathogen Infections -- 12. Noninfectious Diseases Mainly.
Format
e-Book
Location
Online
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Rapid On-Site Evaluation (ROSE) in Diagnostic Interventional Pulmonology : Volume 3, Neoplastic Diseases

https://libcat.nshealth.ca/en/permalink/provcat45299
Jing Feng, Qiang Li, Hongwu Wang, Faguang Jin, Hongmei Zhou, editors. --Singapore: Springer , c2020.
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Online
This book offers cutting-edge evidence on using rapid on-site evaluation (ROSE) for the diagnosis of neoplastic diseases in pulmonology. ROSE has become an efficient interventional diagnostics tool and important reference for lung disease differentiation, increasing the adequacy rate, diagnostic yield and accuracy of interventional pulmonary procedures. By performing a rapid stain in the bronchoscopy suite, with evaluation by a trained physician, ROSE can be used to ensure the collection of sui…
Available Online
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Other Authors
Feng, Jing
Li, Qiang
Wang, Hongwu
Jin, Faguang
Zhou, Hongmei
Responsibility
Jing Feng, Qiang Li, Hongwu Wang, Faguang Jin, Hongmei Zhou, editors
Alternate Title
ROSE in diagnostic interventional pulmonology
Place of Publication
Singapore
Publisher
Springer
Date of Publication
c2020
Physical Description
1 online resource (vi, 169 p.) : 499 illus., 372 illus. in color
ISBN
9789811539107
9789811539091 (Print ed.)
9789811539114 (Print ed.)
9789811539121 (Print ed.)
Subjects (MeSH)
Cytodiagnosis - methods
Lung Neoplasms - diagnosis
Lung Neoplasms - pathology
Specialty
Medical Oncology
Pulmonary Medicine
Abstract
This book offers cutting-edge evidence on using rapid on-site evaluation (ROSE) for the diagnosis of neoplastic diseases in pulmonology. ROSE has become an efficient interventional diagnostics tool and important reference for lung disease differentiation, increasing the adequacy rate, diagnostic yield and accuracy of interventional pulmonary procedures. By performing a rapid stain in the bronchoscopy suite, with evaluation by a trained physician, ROSE can be used to ensure the collection of suitable and sufficient material for ancillary studies in an era of caner-targeted therapy. ROSE holds considerable value in terms of evaluating sampling adequacy for further immunohistochemistry testing, microbiology studies, flow cytometry analysis, and molecular assays, providing a preliminary diagnosis for patient care. The first part of the book discusses the key principles for performing ROSE procedures and reviews key anatomical structures in the lung. It also covers typical cellular characteristics on the ROSE scale for pulmonary solid malignancies. The second part of the book features abundant figures and illustrations of ROSE cytopathology in common neoplastic diseases, e.g. adenocarcinoma, squamous-cell carcinoma and small cell lung cancer, while also exploring more unusual types, e.g. pneumonia-type carcinoma of the lung (PTCL), mucinous adenocarcinoma, lung mixed carcinoma, pulmonary metastases from extrapulmonary primary tumors, large cell neuroendocrine carcinoma (LCNEC), and lymphoma. This book is part of the 4-volume collection ROSE in Diagnostic Interventional Pulmonology.
Contents
1. Cellular Characteristics of ROSE in Pulmonary Solid Malignancies -- 2. Usual-Type Adenocarcinoma -- 3. Usual-Type Squamous-Cell Carcinoma -- 4. Usual-Type Small Cell Lung Cancer -- 5. Pneumonia-Type Carcinoma of Lung (PTCL) -- 6. Mucinous Adenocarcinoma -- 7. Lung Mixed Carcinoma -- 8. Pulmonary Metastases from Extrapulmonary Primary Tumors -- 9. Adenocarcinoma in Special Manifestation -- 10. Large Cell Neuroendocrine Carcinoma (LCNEC) and Lymphoma -- 11. Special Type Malignancies.
Format
e-Book
Location
Online
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Gastric Bypass : Bariatric and Metabolic Surgery Perspectives

https://libcat.nshealth.ca/en/permalink/provcat45305
João Ettinger, Euler Ázaro, Rudolf Weiner, Kelvin D. Higa, Manoel Galvão Neto, Andre Fernandes Teixeira, Muhammad Jawad, editors. --Cham: Springer , c2020.
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Location
Online
This book presents and describes the various uses of gastric bypass in bariatric and metabolic surgery and outlines the different techniques currently available. Furthermore, the possible complications with the procedure and ways to avoid them are also discussed. The use of the gastric bypass for the treatment of diabetes is emphasized and the new indications for the operative treatment of diabetes are featured in detail. Endoscopic uses concerning the gastric bypass are also addressed, coverin…
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Other Authors
Ettinger, João
Ázaro, Euler
Weiner, Rudolf
Higa, Kelvin D.
Galvão Neto, Manoel
Fernandes Teixeira, Andre
Jawad, Muhammad
Responsibility
João Ettinger, Euler Ázaro, Rudolf Weiner, Kelvin D. Higa, Manoel Galvão Neto, Andre Fernandes Teixeira, Muhammad Jawad, editors
Place of Publication
Cham
Publisher
Springer
Date of Publication
c2020
Physical Description
1 online resource (xvi, 491 p.) : 157 illus., 124 illus. in color
ISBN
9783030288037
9783030288020 (Print ed.)
9783030288044 (Print ed.)
9783030288051 (Print ed.)
Subjects (MeSH)
Bariatric Surgery - methods
Gastric Bypass - methods
Obesity - surgery
Specialty
Bariatric Medicine
Surgical Procedures, Operative
Abstract
This book presents and describes the various uses of gastric bypass in bariatric and metabolic surgery and outlines the different techniques currently available. Furthermore, the possible complications with the procedure and ways to avoid them are also discussed. The use of the gastric bypass for the treatment of diabetes is emphasized and the new indications for the operative treatment of diabetes are featured in detail. Endoscopic uses concerning the gastric bypass are also addressed, covering preoperative evaluation, complications treatment, weight regain treatment and endoscopic treatment of obesity. The most advanced techniques and new technologies available for performing gastric bypass surgeries are presented in the most didactic possible way, making use of value-added learning features throughout the text. Gastric Bypass - Bariatric and Metabolic Surgery Perspectives is intended as a practical guide for all those interested and involved with bariatric surgery, including general surgeons, bariatric surgeons, GI surgeons and surgery residents.
Contents
1. History of the Gastric Bypass -- 2. Gastric Bypass: Mechanisms of Functioning -- 3. Morbid Obesity -- 4. Obesity and Related Diseases -- 5. Preparing for Gastric Bypass -- 6. Preoperative Weight Loss in Gastric Bypass -- 7. Preoperative Testing and Counseling -- 8. Patient Selection for Metabolic Surgery -- 9. Psychiatric Issues During the Postoperative Period of Bariatric Surgery -- 10. Sleep-Disordered Breathing and Bariatric Surgery -- 11. The Superobese Patient -- 12. Airway Evaluation and Management -- 13. Positioning the Bariatric Surgical Patient -- 14. Developing the Laparoscopic Gastric Bypass -- 15. Systemic Inflammation in the Morbidly Obese Patient -- 16. Banded Gastric Bypass by Fobi Ring: Technique and Results -- 17. Mini-Gastric Bypass and One-Anastomosis Gastric Bypass: Rationale -- 18. Simplified Gastric Bypass: The Brazilian Technique -- 19. Roux-en-Y Gastric Bypass in the Elderly Patient -- 20. Gastric Bypass Reoperation for Weight Regain -- 21. Conversion from Sleeve to Bypass -- 22. Gastrojejunostomy Testing -- 23. Closing the Mesenteric Defects -- 24. Preventing Complications -- 25. Laparoscopic Gastric Bypass: Tricks and Tips -- 26. Psychiatric Assistance in Bariatric Surgery -- 27. Perioperative Complications -- 28. Abdominal Pain After Gastric Bypass -- 29. Marginal Ulceration After (Laparoscopic) Roux-en-Y Gastric Bypass: Pathophysiology, Diagnostics, Treatment, and Prevention -- 30. Rhabdomyolysis -- 31. Depressive Disorders, Alcohol Use Disorders, and Suicidality in Bariatric Surgery -- 32. Nutritional Complications -- 33. Eating Disorders -- 34. Gallbladder Stones and Choledocholitiasis -- 35. Hypoglycemia After Gastric Bypass -- 36. Dumping Syndrome -- 37. Endoscopic Treatment of Roux-en-Y Gastric Bypass Complications -- 38. Endoscopic Treatment of Weight Regain After Gastric Bypass -- 39. Laparoscopic Bariatric Surgery Training and the Credentialing Process -- 40. Training and Credentialing the Robotic Bariatric Surgeon -- 41. Mechanisms of Control of Type 2 Diabetes with Gastric Bypass -- 42. The Gut and Type 2 Diabetes Mellitus -- 43. Shifts in the Intestinal Microbiota After Gastric Bypass -- 44. Infection: Diagnosis and Treatment -- 45. Gastric Bypass in Patients with Metabolic Syndrome -- 46. Gastric Bypass for Type 2 Diabetes Mellitus on BMI >35 -- 47. Gastric Bypass for Type 2 Diabetes Mellitus on BMI < 35 -- 48. Postoperative Care -- 49. Mini Gastric Bypass: Why It Is Better than Gastric Bypass in India -- 50. Can Bariatric Surgery Improve the Microvascular Complications of Type 2 Diabetes?
Format
e-Book
Location
Online
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Pulmonary Pathology : A Practical Guide

https://libcat.nshealth.ca/en/permalink/provcat45543
Helmut Popper, Bruno Murer. --Cham: Springer , c2020.
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This book provides an up-to-date overview of diagnostics in lung and pleura pathology. It helps surgical and clinical pathologist solve problem cases in lung and pleura tumor pathology as well as in other fields of pulmonary/pleura pathology such as interstitial lung disease, rare tumors, metabolic diseases, infectious pneumonias, pneumoconiosis, drug induced lung diseases, developmental and pediatric pulmonary pathology. Focusing on practical issues and providing numerous illustrated examples …
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Author
Popper, Helmut
Other Authors
Murer, Bruno
Responsibility
Helmut Popper, Bruno Murer
Place of Publication
Cham
Publisher
Springer
Date of Publication
c2020
Physical Description
1 online resource (x, 597 p.) : 1693 illus., 1669 illus. in color
Series Title
Essentials of diagnostic pathology
ISBN
9783030226640
9783030226626 (Print ed.)
9783030226633 (Print ed.)
ISSN
2194-6256
Subjects (MeSH)
Lung Diseases - pathology
Pleural Diseases - pathology
Specialty
Pathology
Pulmonary Medicine
Abstract
This book provides an up-to-date overview of diagnostics in lung and pleura pathology. It helps surgical and clinical pathologist solve problem cases in lung and pleura tumor pathology as well as in other fields of pulmonary/pleura pathology such as interstitial lung disease, rare tumors, metabolic diseases, infectious pneumonias, pneumoconiosis, drug induced lung diseases, developmental and pediatric pulmonary pathology. Focusing on practical issues and providing numerous illustrated examples of typical and atypical cases, it guides residents as well as experienced pathologists through the problems and pitfalls in pulmonary and pleura pathology. References have been kept to a minimum.
Contents
1. Preneoplastic and Preinvasive Lesions -- 2. Adenocarcinoma -- 3. Squamous Cell Carcinoma -- 4. Small Cell Carcinoma -- 5. Large Cell Neuroendocrine Carcinoma -- 6. Carcinoid -- 7. Large Cell Carcinoma -- 8. Lymphoepithelioma-Like Carcinoma -- 9. Carcinoma with Rhabdoid Features -- 10. Salivary Gland-Type Carcinomas -- 11. Sarcomatoid Carcinomas -- 12. Adenosquamous Carcinoma -- 13. Benign Epithelial Tumors -- 14. Benign Mesenchymal Tumors -- 15. Malignant Mesenchymal Tumors -- 16. Lymphoid Tumors -- 17. Tumors of Childhood -- 18. Tumors of the Pleura -- 19. Metastasis -- 20. Cystic Lesions -- 21. Congenital Pulmonary Airway Malformation (CPAM) Types 1–4 -- 22. Smoking-Related Diseases -- 23. Bronchiolitis -- 24. Acute Pneumonia -- 25. Granulomatous Pneumonias -- 26. Foreign and Xenobiotic Substances -- 27. Fibrosing Pneumonias (Interstitial Pneumonias) -- 28. Autoimmune Diseases -- 29. Eosinophilic Pneumonias (EP) -- 30. Vasculitis -- 31. Alveolar Hemorrhage -- 32. Metabolic Lung Diseases -- 33. Pneumoconiosis -- 34. Hypertension and Vasculopathies.
Format
e-Book
Publication Type
Atlas
Location
Online
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Management of Severe Traumatic Brain Injury : Evidence, Tricks, and Pitfalls

https://libcat.nshealth.ca/en/permalink/provcat45583
Terje Sundstrøm, Per-Olof Grände, Teemu Luoto, Christina Rosenlund, Johan Undén, Knut Gustav Wester, editors. (Second edition) --Cham: Springer , c2020.
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Online
This comprehensively updated second edition features major revisions, 24 new chapters and more than 40 new authors, reflecting both the advances and key challenges within the field. Offering a systematic guide to the management of children and adults with severe traumatic brain injury throughout the entire chain of care, it includes evidence-based recommendations for each diagnostic and therapeutic measure, together with tips, tricks and pitfalls. The authors are all highly experienced clinicia…
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Other Authors
Sundstrøm, Terje
Grände, Per-Olof
Luoto, Teemu
Rosenlund, Christina
Undén, Johan
Wester, Knut Gustav
Responsibility
Terje Sundstrøm, Per-Olof Grände, Teemu Luoto, Christina Rosenlund, Johan Undén, Knut Gustav Wester, editors
Edition
Second edition
Place of Publication
Cham
Publisher
Springer
Date of Publication
c2020
Physical Description
1 online resource (xxxi, 689 p.) : 83 illus., 38 illus. in color
ISBN
9783030393830
9783030393823 (Print ed.)
9783030393847 (Print ed.)
9783030393854 (Print ed.)
Subjects (MeSH)
Brain Injuries, Traumatic - therapy
Specialty
Critical Care
Emergency Medicine
Neurology
Neurosurgery
Traumatology
Abstract
This comprehensively updated second edition features major revisions, 24 new chapters and more than 40 new authors, reflecting both the advances and key challenges within the field. Offering a systematic guide to the management of children and adults with severe traumatic brain injury throughout the entire chain of care, it includes evidence-based recommendations for each diagnostic and therapeutic measure, together with tips, tricks and pitfalls. The authors are all highly experienced clinicians and researchers who work with neurotrauma patients on a daily basis, and the editors represent the Scandinavian Neurotrauma Committee. The book helps professionals provide more systematic and higher-quality care in prehospital settings, primary hospitals, neurosurgical departments, neurointensive care units, and rehabilitation facilities. It is intended for all healthcare personnel involved in the multidisciplinary management of patients with head injuries, especially those in emergency care, neurosurgery, anesthesiology, radiology, and rehabilitation.
Contents
Part I. Traumatic brain injury as a public health problem -- Epidemiological aspects -- Challenges in low- and middle income countries -- Challenges in the elderly -- Challenges in children -- Biomechanics and prevention -- Part II. Classification and assessment -- Pathophysiology of severe traumatic brain injury -- Classification of head injury -- Primary clinical assessment -- Part III. Prehospital management -- Prehospital guidelines -- What the neurosurgeon and the trauma team want to know: what, who, when, and where? -- Transportation -- Part IV. Admission, diagnostics and planning -- The trauma team concept -- Trauma protocol (ABCDE) -- Hospital response to mass casualty incidents -- Cervical spine injury -- Blast-induced injury -- Radiological evaluation of head trauma -- Radiological evaluation of cervical spine trauma -- Blood samples -- To treat or not to treat in the acute setting (withholding) and withdrawal of treatment -- Potential organ donor: organ donor management -- Ethical aspects and communication -- Part V. Acute surgical treatment -- Basic trauma craniotomy -- Surgical management of traumatic intracranial haematomas -- Surgical management of penetrating brain injuries -- Decompressive craniectomy -- Skull fractures -- Vessel injuries -- Insertion of intracranial monitoring devices -- Maxillofacial fractures -- Considerations in patients with concomitant cervical spine injuries -- Soft tissue injuries -- Surgery outside neurosurgical units -- Planning of cranial and extracranial surgery in multitraumatised patients -- Part VI. Perioperative anaesthesia -- Choice of anaesthesia, drugs and medications -- Blood pressure, CO2 and oxygen saturation -- Intracranial pressure reduction -- Part VII. Monitoring in neurointensive care Secondary clinical assessment -- A wake-up test in the neurointensive care management of patients with severe TBI: pros and cons -- Intracranial pressure (ICP):Theoretical and practical aspects -- Brain tissue oxygen monitoring -- Monitoring microdialysis -- Jugular bulb measurements (SJVO2) -- Cerebral blood flow (CBF) and cerebral metabolic rate (CMR) -- Transcranial Doppler (TCD) -- Near infrared spectroscopy (NIRS) or cerebral oximetry -- Clinical Neurophysiology: Evoked Potentials -- Clinical Neurophysiology: Continous EEG Monitoring -- Imaging of severe traumatic brain injury in the neurointensive care unit -- Serum protein biomarkers in the management of severe traumatic brain injury -- Cardiopulmonary aspects -- Renal aspects -- Neuroendocrine aspects -- Part VIII. Treatment in neurointensive care -- Guidelines for treatment of patients with severe traumatic brain injury -- The Lund therapy: a physiological approach -- Pharmacological neuroprotection -- Subacute surgery in neurointensive care -- Management of extracranial injuries -- CSF Drainage -- Hyperventilation -- Osmotherapy -- Barbiturates for ICP management -- Management of fluid and electrolyte disturbances -- Sedation: including pain treatment and withdrawal symptoms -- Nutrition -- Management of CNS-related infection -- Management of extracranial infections -- Temperature management -- Seizures -- Paroxysmal sympathetic hyperactivity -- Prophylaxis against venous thromboembolism -- Coagulopathy (bleeding tendency) -- Corticosteroids -- Management of acute psychiatric problems -- Part IX. Rehabilitation and follow-up -- Rehabilitation after severe TBI -- Long-term follow-up -- Part X. Outcome and prognosis -- General overview -- Somatic consequences -- Neuropsychiatric consequences -- Neuropsychological perspectives -- Neurosurgical challenges -- Minimally conscious and vegetative state -- Specific peadiatric concerns -- Socioeconomic consequences -- Subacute MR Imaging: Traumatic axonal injury, brain stem lesions and prognostic factors -- Neurodegeneration and dementia -- Part XI. Research in severe TBI -- The neurointensive care unit as a platform for advanced clinical research -- Current state-of-the-art in neurotrauma research.
Format
e-Book
Location
Online
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The Chiari Malformations

https://libcat.nshealth.ca/en/permalink/provcat45585
R. Shane Tubbs, Mehmet Turgut, W. Jerry Oakes, editors. (Second edition) --Cham: Springer , c2020.
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Online
This unique, contemporary book is the successor edition of a ground-breaking, authoritative title devoted to the pathology and treatment of chiari malformations. Since an abundance of research and development has occurred after the publication of the Chiari Malformations this updated title meets the market need for a reference that reflects such advances in the field. Chiari Malformations, 2nd Edition is divided into nine sections. Opening sections feature chapters on general aspects, diagnosti…
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Other Authors
Tubbs, R. Shane
Turgut, Mehmet
Oakes, W. Jerry
Responsibility
R. Shane Tubbs, Mehmet Turgut, W. Jerry Oakes, editors
Edition
Second edition
Place of Publication
Cham
Publisher
Springer
Date of Publication
c2020
Physical Description
1 online resource (xix, 627 p.) : 291 illus., 151 illus. in color
ISBN
9783030448622
9783030448615 (Print ed.)
9783030448639 (Print ed.)
9783030448646 (Print ed.)
Subjects (MeSH)
Arnold-Chiari Malformation
Specialty
Neuroanatomy
Pathology
Abstract
This unique, contemporary book is the successor edition of a ground-breaking, authoritative title devoted to the pathology and treatment of chiari malformations. Since an abundance of research and development has occurred after the publication of the Chiari Malformations this updated title meets the market need for a reference that reflects such advances in the field. Chiari Malformations, 2nd Edition is divided into nine sections. Opening sections feature chapters on general aspects, diagnostic features and clinical presentation. These are followed by sections on differential diagnosis, treatment and prognosis. Finally, the book closes with an extensive discussion on research, related pathologies and patient resources. Expertly written chapters are supplemented with numerous high-quality illustrations and images to aid in visual learning. An impressive, nuanced successor, Chiari Malformations, 2nd edition, is an invaluable resource for neuroscientists and clinicians at all levels, as well as graduate students to specific research scientists studying this region.
Contents
Part I. History and Classifications -- 1. A History of the Chiari Malformations -- 2. Defining the Chiari Malformations: Past and Newer Classifications -- 3. Newer Subsets: Chiari 1.5 and Chiari 0 Malformations -- Part II. Embryology and Anatomy -- 4. Embryology of the Craniocervical Junction and Posterior Cranial Fossa -- 5. Embryology and Pathophysiology of the Chiari I and II Malformations -- 6. The Occipital Bone: Review of its Embryology and Molecular Development -- 7. The Proatlas -- 8. Development of the Atlas and its Variations -- 9. The Odontoid Process -- 10. Surgical Anatomy of the Craniocervical Junction Relevant to Chiari Malformations -- Part III. Pathology -- 11. Pathology of Chiari I and II Malformations -- 12. Research on the Pathophysiology of Chiari I-Related Symptoms and Syringomyelia, with Emphasis on Dynamic MRI Techniques -- 13. The Chiari Malformations and Hydrocephalus -- 14. Cerebellar Tonsillar Ischemia and Cysts in the Chiari I Malformation -- 15. Syringomyelia and the Chiari Malformations -- 16. Non-Hindbrain-Related Syringomyelia -- 17. Chiari and Scoliosis -- 18. Associated Bony Malformations and Instability in the Chiari I Malformation -- 19. Ventral Decompression for Chiari Malformations -- 20. Chiari I Malformation and Craniosynostosis -- Part IV. Epidemiology, Natural History, and Genetics -- 21. Epidemiology of Chiari I Malformation -- 22. Natural History of Chiari Malformations -- 23. Genetics of the Chiari I and II Malformations -- Part V. Diagnostics -- 24. Electrophysiological Diagnostics in Chiari Malformation -- 25. Radiology -- 26. Measurement of the Volume of the Posterior Cranial Fossa using MRI -- 27. Intraoperative Ultrasound in Chiari Type I Malformation -- 28. Advanced Imaging of Chiari I Malformations -- Part VI. Clinical Presentations -- 29. Clinical Presentation of Pediatric Chiari I Malformations -- 30. Benign Chiari I Malformation -- 31. Unusual Presentations of the Chiari I Malformation -- 32. Clinical Presentation Adult Chiari I -- 33. Acute and Sudden Presentations of the Chiari Malformations -- 34. Associated Disorders of Chiari Type I Malformations -- 35. Association Between Fibromyalgia, Chronic Fatigue, and the Chiari I Malformation -- 36. Symptoms of the Chiari II Malformation -- Part VII. Treatment, Outcomes, and Complications -- 37. Treatment of the Pediatric Chiari I Malformation -- 38. Treatment of the Adult Chiari I Malformation -- 39. Treatment of the Chiari II Malformation -- 40. Chiari Type II Malformation: Reversibility Following Myelomeningocele Closure -- 41. Duraplasty Versus Non-dural Opening for the Treatment of Pediatric Chiari Malformation Type I -- 42. Chiari Decompression Outcomes Using Ligamentum Nuchae Harvest and Duraplasty in Pediatric Patients with Chiari I Malformation -- 43. Complications of Chiari Surgery -- 44. Secondary Interventions for Chiari I Malformation -- 45. Outcomes for the Surgical Management of Chiari I and Chiari II Malformations -- Part VIII. Miscellaneous -- 46. Chiari-Like Malformation in Dogs -- 47. Experimental Models of Chiari Malformations -- 48. Predictive Analysis in Chiari Type I Malformation -- 49 -- Treatment Costs of Chiari Type I Malformation -- 50. A Multidisciplinary Clinic for the Management of Chiari I Malformations -- 51. Chiari Malformations: a Patient’s Guide -- Part IX. Conclusions -- 52. Conclusions.
Format
e-Book
Location
Online
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Damage-Associated Molecular Patterns in Human Diseases : Volume 2: Danger Signals as Diagnostics, Prognostics, and Therapeutic Targets

https://libcat.nshealth.ca/en/permalink/provcat45638
Walter Gottlieb Land. --Cham: Springer , c2020.
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This book is a continuance of the topic: “DAMPs in Human Diseases”, the basics of which were described in a first volume by the same author. This second volume presents our current understanding of the impact of sterile stress/injury-induced innate immune responses on the etiopathogenesis of human diseases by focusing on those diseases that are pathogenetically dominated by DAMPs, i.e., on polytrauma, various solid organ injuries (brain, lung, kidney, liver), atherosclerosis, and cerebro-cardio…
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Author
Land, Walter Gottlieb
Responsibility
Walter Gottlieb Land
Alternate Title
Danger signals as diagnostics, prognostics, and therapeutic targets
Place of Publication
Cham
Publisher
Springer
Date of Publication
c2020
Physical Description
1 online resource (xxxix, 629 p.) : 45 illus. in color
ISBN
9783030538682
9783030538675 (Print ed.)
9783030538699 (Print ed.)
9783030538705 (Print ed.)
Subjects (MeSH)
Biomarkers
Immunologic Techniques
Molecular Medicine
Pathogen-Associated Molecular Pattern Molecules
Stress, Physiological - immunology
Wounds and Injuries - immunology
Specialty
Diagnosis
Molecular Medicine
Pathology
Abstract
This book is a continuance of the topic: “DAMPs in Human Diseases”, the basics of which were described in a first volume by the same author. This second volume presents our current understanding of the impact of sterile stress/injury-induced innate immune responses on the etiopathogenesis of human diseases by focusing on those diseases that are pathogenetically dominated by DAMPs, i.e., on polytrauma, various solid organ injuries (brain, lung, kidney, liver), atherosclerosis, and cerebro-cardiovascular diseases. Our growing understanding of the pathogenetic function of activating DAMPs and suppressive DAMPs (“SAMPs”) is used as a point of departure to explore how these molecules can be used as biomarkers to extend and improve current diagnostic and prognostic modalities. Moreover, this new knowledge about the pathogenetic function of DAMPs and SAMPs is taken as a sound and plausible reason for discussing their implications for present and future treatment of the diseases addressed here. In this context, the focus is on the potential of DAMPs as future therapeutic targets and SAMPs as future therapeutics, applied in strict compliance with safety precautions, as also recommended in this work. The book is intended for professionals from all medical and paramedical disciplines who are interested in applying innovative data from inflammation and immunity research to clinical practice. The readership will include practitioners and clinicians working in the broad field of acute and chronic inflammatory/fibrotic diseases, in particular, traumatologists and intensivists; neurologists and neurosurgeons; cardiologists and cardiac surgeons; pulmonologists and thoracic surgeons; vascular surgeons; nephrologists; gastroenterologists and hepatologists; and pharmacists. Also available: Damage-Associated Molecular Patterns in Human Diseases, Vol. 1: Injury-Induced Innate Immune Responses.
Contents
Part I. Prologue -- Perspectives of the Danger/Injury Model in Immunology -- Part II. A Select, Clinically Oriented Update of Topics Presented in “Damage-Associated Molecular Patterns in Human Diseases, Volume 1: Injury-Induced Innate Immune Responses" -- Pattern Recognition Molecules -- The Growing World of DAMPs -- The Growing Clinical Relevance of Cellular Stress Responses and Regulated Cell Death -- DAMP-Promoted Efferent Innate Immune Responses in Human Diseases: Inflammation -- DAMP-Promoted Efferent Innate Immune Responses in Human Diseases: Fibrosis -- Part III. DAMPs and SAMPs in Traumatic Disorders, Atherosclerosis, and Cerebro-Cardiovascular Diseases -- DAMPs and SAMPs as Molecular Biomarkers, Therapeutic Targets, and Therapeutics -- DAMP-Controlled and Uncontrolled Responses to Trauma: Wound Healing and Polytrauma -- Solid Organ Injury -- Atherosclerosis -- Cerebro - Cardiovascular Diseases -- Part IV. Epilogue -- The “DAMPome” as a Key Player in the Pathogenesis of Human Diseases.
Format
e-Book
Location
Online
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Non-Alcoholic Fatty Liver Disease : A 360-degree Overview

https://libcat.nshealth.ca/en/permalink/provcat45659
Elisabetta Bugianesi, editor. --Cham: Springer , c2020.
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Location
Online
The goal of this book is to promote awareness of non-alcoholic fatty liver disease (NAFLD) – which is rapidly replacing viral hepatitis as the leading cause of chronic liver disease in Europe, North and South America and Asia – and to share the latest information on evolving approaches to diagnosis and treatment. The book offers a comprehensive overview of the current topics of interest in the field, and provides clinical guidance on NAFLD through a multidisciplinary approach based on the lates…
Available Online
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Other Authors
Bugianesi, Elisabetta
Responsibility
Elisabetta Bugianesi, editor
Place of Publication
Cham
Publisher
Springer
Date of Publication
c2020
Physical Description
1 online resource (x, 362 p.) : 45 illus., 41 illus. in color
ISBN
9783319958286
9783319958279 (Print ed.)
9783319958293 (Print ed.)
Subjects (MeSH)
Non-alcoholic Fatty Liver Disease
Specialty
Gastroenterology
Abstract
The goal of this book is to promote awareness of non-alcoholic fatty liver disease (NAFLD) – which is rapidly replacing viral hepatitis as the leading cause of chronic liver disease in Europe, North and South America and Asia – and to share the latest information on evolving approaches to diagnosis and treatment. The book offers a comprehensive overview of the current topics of interest in the field, and provides clinical guidance on NAFLD through a multidisciplinary approach based on the latest scientific understanding of this multisystemic disease, involving the expertise of specialists including hepatologists, diabetologists, and cardiologists. The respective contributions address various aspects, including the newly released international guidelines, novel diagnostic modalities, and new experimental drugs. The work will appeal to a broad readership, from residents in internal medicine to specialists.
Contents
1. Obesity and NAFLD: Same Problem? -- 2. The Burden of NAFLD Worldwide -- 3. Histopathology of Nonalcoholic Fatty Liver Disease -- 4. NAFLD and Insulin Resistance: A Multisystemic Disease -- 5. Etiopathogenesis of NAFLD: Diet, Gut, and NASH -- 6. Mechanisms of Fibrogenesis in NASH -- 7. The Natural History of NAFLD: Environmental vs. Genetic Risk Factors -- 8. NAFLD, Diabetes, and Other Endocrine Diseases: Clinical Implications -- 9. NAFLD and Cardiovascular and Cardiac Disease: Clinical Implications -- 10. NAFLD, Hepatocellular Carcinoma, and Extrahepatic Cancers -- 11. NAFLD in Children: Implication for the Future -- 12. Diagnostic Algorithm for the Identification of NAFLD in Primary Care -- 13. Non-invasive Diagnostic Approach to NASH: Biological Markers -- 14. Noninvasive Diagnostic Approach to NASH: Radiological Diagnostics -- 15. Dietary Approach to NAFLD -- 16. Physical Activity in NAFLD: What and How Much? -- 17. Pharmacological Options for NASH -- 18. Bariatric Surgery and NASH: A Feasible Option -- 19. Liver Transplantation and NAFLD/NASH.
Format
e-Book
Location
Online
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