Congenital Hyperinsulinism : A Practical Guide to Diagnosis and Management
https://libcat.nshealth.ca/en/permalink/provcat44051
Diva D. De León-Crutchlow, Charles A. Stanley, editors.
--Cham:
Humana Press
, 2019.
- Available Online
- View e-Book
- Location
- Online
This unique book is a practical guide for the clinician faced with the challenge of diagnosing and managing neonates, infants and children with congenital hyperinsulinism (HI), within the framework of pathophysiology and molecular genetics. Major advances have been made in HI research over the past two decades, and with this better understanding of the molecular genetics of HI, a “personalized” approach to management according to the type of hyperinsulinism, and particularly according to the li…
- Available Online
- View e-Book
- Other Authors
- De León-Crutchlow, Diva D.
- Stanley, Charles A.
- Responsibility
- Diva D. De León-Crutchlow, Charles A. Stanley, editors
- Place of Publication
- Cham
- Publisher
- Humana Press
- Date of Publication
- 2019
- Physical Description
- 1 online resource (xv, 165 p.) : 22 illus., 12 illus. in color
- Series
- Contemporary Endocrinology
- Series Title
- Contemporary endocrinology
- ISBN
- 9783030029616
- 9783030029609 (Print ed.)
- 9783030029623 (Print ed.)
- ISSN
- 2523-3785
- Specialty
- Diabetes Mellitus
- Abstract
- This unique book is a practical guide for the clinician faced with the challenge of diagnosing and managing neonates, infants and children with congenital hyperinsulinism (HI), within the framework of pathophysiology and molecular genetics. Major advances have been made in HI research over the past two decades, and with this better understanding of the molecular genetics of HI, a “personalized” approach to management according to the type of hyperinsulinism, and particularly according to the likelihood of focal hyperinsulinism, is starting to emerge. The opening chapter discusses HI diagnosis using biochemical approaches and phenotype characterization. The various forms of HI are then presented in detail in three main categories: diazoxide-responsive, diazoxide-unresponsive and syndromic HI. Both medical and surgical management strategies are then discussed, covering imaging, histology, surgical approach, and post-operative management. Complications, such as feeding problems, and long-term outcomes, such as neurodevelopmental issues, are carefully considered in the final chapter. Practical and user-friendly, Congenital Hyperinsulinism is the go-to resource for pediatric endocrinologists, residents and fellows, general pediatricians and neonatologists.
- Contents
- Approach to the Diagnosis of Neonates and Infants with Persistent Hypoglycemia -- Diazoxide-Responsive Forms of Congenital Hyperinsulinism -- Diazoxide-Unresponsive Forms of Congenital Hyperinsulinism -- Syndromic Causes of Congenital Hyperinsulinism -- Molecular Diagnosis of Congenital Hyperinsulinism -- Medical Management of Hyperinsulinism -- 18F-DOPA PET -- Histopathology of the Pancreas in Congenital Hyperinsulinism -- Surgery for Congenital Hyperinsulinism -- Perioperative Management of Hyperinsulinism -- Management of the Child with Persistent Hypoglycemia After Surgery -- Management of Diabetes and Pancreatic Insufficiency after Pancreatectomy -- Feeding Problems in Congenital Hyperinsulinism -- Neurodevelopmental Outcomes.
- Format
- e-Book
- Location
- Online
Movement Disorder Emergencies : Diagnosis and Treatment
https://libcat.nshealth.ca/en/permalink/provcat40762
Steven J. Frucht, editor.
(Second edition)
--Totowa, NJ:
Humana Press
, c2013.
- Available Online
- View e-Book
- Location
- Online
Updated and expanded with nine additional chapters, Movement Disorder Emergencies: Diagnosis and Treatment, Second Edition is an indispensable resource for general neurologists, specialists, fellows, and residents eager to improve their approach toward the patient with a movement disorder emergency. In this comprehensive second edition, prominent neurologists from around the world logically and systematically review the major movement disorder emergencies, instructing the reader on how optimall…
- Available Online
- View e-Book
- Other Authors
- Frucht, Steven J
- Responsibility
- Steven J. Frucht, editor
- Edition
- Second edition
- Place of Publication
- Totowa, NJ
- Publisher
- Humana Press
- Date of Publication
- c2013
- Physical Description
- 1 online resource (xviii, 401 p. : 25 illus.)
- Series Title
- Current clinical neurology
- ISBN
- 9781607618355
- 9781607618348 (print ed.)
- Subjects (MeSH)
- Diagnosis, Differential
- Emergencies
- Movement Disorders - diagnosis
- Movement Disorders - therapy
- Neuromuscular Manifestations
- Abstract
- Updated and expanded with nine additional chapters, Movement Disorder Emergencies: Diagnosis and Treatment, Second Edition is an indispensable resource for general neurologists, specialists, fellows, and residents eager to improve their approach toward the patient with a movement disorder emergency. In this comprehensive second edition, prominent neurologists from around the world logically and systematically review the major movement disorder emergencies, instructing the reader on how optimally to recognize and manage these problems. The authors cover a broad range of disorders, including acute dystonic reactions, neuroleptic malignant syndrome, startle syndromes, tic emergencies, and others; and they stress the importance of certain obvious diagnoses such as Wilson's disease, dopa-responsive dystonia, and Whipple's disease, in which delayed diagnosis in less emergent situations can lead to slowly evolving and often irreversible neurologic damage with tragic consequences. In addition, nine topics not covered in the first edition are provided, including genetic counseling and testing crises, suicide risk, psychogenic movement disorders, and others. Patient vignettes at the beginning of each chapter focus the reader's attention and highlight the urgency of the problem. Since astute clinical diagnosis of many movement disorders is still largely dependent on visual pattern recognition in the clinic, an accompanying online collection of physician-patient vignettes illustrates virtually all of the movement disorders described in the text. Importantly, the authors also discuss a range of new treatment paradigms that have emerged since publication of the first edition, especially deep brain stimulation. Authoritative and a leading text in the field, Movement Disorder Emergencies: Diagnosis and Treatment, Second Edition is an established, practical reference that continues to achieve excellence in the field of diagnosis and management of movement disorder emergencies.
- Contents
- A Brief Introduction to Movement -- Acute Parkinsonism -- Parkinsonism-Hyperpyrexia Syndrome in Parkinson's Disease -- Neuroleptic Malignant Syndrome -- Malignant Catatonia -- Psychosis and Parkinson's Disease -- Abductor Paresis in Shy-Drager Disease -- Movement Disorder Emergencies of the Upper Aerodigestive Tract -- Dystonic Storm -- Pseudodystonic Emergencies -- Tardive and Neuroleptic-Induced Emergencies -- Hemiballism-Hemichorea -- Sydenham's chorea, PANDAS and other Post-streptococcal neurological disorders -- Emergencies in Huntington's Disease -- Acute Spinal Rigidity -- Tic Emergencies -- Malignant Phonic Tics -- Serotonin Syndrome -- Risks and Dangers From Hyperekplexia and Other Startle Disorders -- Perioperative Emergencies Associated with Deep Brain Stimulation -- Psychogenic Movement Disorders -- Anti-NMDA Receptor Encephalitis and Other Autoimmune and Paraneoplastic Movement Disorders -- Wilson's Disease -- Dopa-Responsive Dystonia -- Whipple's Disease -- Driving Risk in Patients with Movement Disorders -- Genetics and Genetic Counseling Related Issues -- Suicide Risk in Parkinson's Disease.
- Format
- e-Book
- Publication Type
- Case Reports
- Location
- Online
Nuclear Medicine in Oncology : Molecular Imaging and Target Therapy
https://libcat.nshealth.ca/en/permalink/provcat44463
Gang Huang, editor.
--Singapore:
Springer ; Shanghai Jiao Tong University Press
, c2019.
- Available Online
- View e-Book
- Location
- Online
This book introduces molecular imaging and target therapy in various cancers. The first part is the subjects and primary focused on the basics of nuclear physics, radiation dosimetry, nuclear medicine equipment and small animal imaging equipment. The second part is about the radiopharmaceutical and commonly used clinical radiopharmaceuticals, including positron emission imaging agent, single photon emission imaging agent, and radionuclide therapy agents as well as their radioactive preparation,…
- Available Online
- View e-Book
- Other Authors
- Huang, Gang
- Responsibility
- Gang Huang, editor
- Place of Publication
- Singapore
- Publisher
- Springer ; Shanghai Jiao Tong University Press
- Date of Publication
- c2019
- Physical Description
- 1 online resource (xi, 346 p.) : 247 illus., 157 illus. in color
- ISBN
- 9789811374586
- 9789811374579 (Print ed.)
- 9789811374593 (Print ed.)
- 9789811374609 (Print ed.)
- Subjects (MeSH)
- Molecular Imaging
- Molecular Targeted Therapy
- Neoplasms - diagnostic imaging
- Neoplasms - radiotherapy
- Specialty
- Diagnostic Imaging
- Medical Oncology
- Abstract
- This book introduces molecular imaging and target therapy in various cancers. The first part is the subjects and primary focused on the basics of nuclear physics, radiation dosimetry, nuclear medicine equipment and small animal imaging equipment. The second part is about the radiopharmaceutical and commonly used clinical radiopharmaceuticals, including positron emission imaging agent, single photon emission imaging agent, and radionuclide therapy agents as well as their radioactive preparation, quality control, and a brief clinical application were included. Also, this part introduces a number of new imaging agents which were potential value of clinical applications. In the third part, the clinical application of the conventional imaging agent 18F-FDG in different tumors and neurodegenerative diseases and 18F-Dopa imaging in the nervous system are discussed. Besides the clinical applications of 99mTc labeled radiopharmaceuticals in parathyroid disease, coronary heart disease, myocardial infarction, sentinel lymph node, metastatic bone tumors, liver and gallbladder disease in children are introduced. Finally, the applications of radionuclide 131I on treatments of Graves' disease and differentiated thyroid cancer and metastases are investigated respectively. This book is a useful reference for professionals engaged in nuclear medicine and clinical research, including clinical nuclear medicine physicians, nuclear medicine engineers and nuclear medicine pharmacists.
- Contents
- 1. Glucose metabolism imaging -- 2. Clinical utility of 18F-FDG PET/CT in breast cancer management and targeted therapy -- 3. The application of 18F-FDG PET/CT in diagnose and therapy of non-small cell lung cancer -- 4. Clinical application of 18F-FDG PET/CT in lymphoma -- 5. Clinical utility of 18F-FDG PET/CT scanning in urological cancers management -- 6. Gynecologic tumor PET / CT imaging -- 7. Molecular imaging and targeted therapy of gastrointestinal cancer -- 8. Head and neck cancer -- 9. Molecular imaging and targeted therapy of malignant melanoma -- 10. Role of 18F-FDG PET/CT in pediatric oncology -- 11. Molecular imaging -- 12. Receptor targeted radionuclide imaging (RTRI) and peptide receptor radionuclide therapy (PRRT) -- 13. Radioimmunoimaging and targeted therapy -- 14. Apoptosis imaging -- 15. Radionuclide gene and reporter gene imaging -- 16. Na+/I- symporter target for thyroid disease imaging and treatment -- 17. Molecular imaging and targeted therapy in neurology -- 18. Nuclear cardiolgy -- 19. Equipment for imaging and mechanism, radiation protection -- 20. Molecular imaging probe.
- Format
- e-Book
- Location
- Online
Radiopharmaceuticals : A Guide to PET/CT and PET/MRI
https://libcat.nshealth.ca/en/permalink/provcat45051
Ferdinando Calabria, Orazio Schillaci, editors.
(Second edition)
--Cham:
Springer
, c2020.
- Available Online
- View e-Book
- Location
- Online
This book provides a rapid and concise guide to PET (PET/CT and PET/MRI) molecular imaging, concentrating extensive information on PET radiopharmaceuticals in a single volume. The book reflects the rapid development of several PET tracers over the last decade, as a result of which the “traditional” PET/CT with 18F-FDG, the “cornerstone” of PET imaging, is now only one of several available options, which use different tracers for different diseases. For the same reason, PET imaging is no longer …
- Available Online
- View e-Book
- Other Authors
- Calabria, Ferdinando
- Schillaci, Orazio
- Responsibility
- Ferdinando Calabria, Orazio Schillaci, editors
- Edition
- Second edition
- Place of Publication
- Cham
- Publisher
- Springer
- Date of Publication
- c2020
- Physical Description
- 1 online resource (xii, 234 p.) : 193 illus., 184 illus. in color
- ISBN
- 9783030277796
- 9783030277789 (Print ed.)
- 9783030277802 (Print ed.)
- 9783030277819 (Print ed.)
- Subjects (MeSH)
- Positron-Emission Tomography
- Radiopharmaceuticals
- Specialty
- Diagnostic Imaging
- Pharmacology
- Radiography
- Abstract
- This book provides a rapid and concise guide to PET (PET/CT and PET/MRI) molecular imaging, concentrating extensive information on PET radiopharmaceuticals in a single volume. The book reflects the rapid development of several PET tracers over the last decade, as a result of which the “traditional” PET/CT with 18F-FDG, the “cornerstone” of PET imaging, is now only one of several available options, which use different tracers for different diseases. For the same reason, PET imaging is no longer limited to the field of oncology. In the editors’ experience, students in medicine and residents in nuclear medicine and radiology have limited access to scientific papers concerning novel PET tracers. Moreover, these papers generally focus on a single PET radiopharmaceutical. With approx. 20 radiopharmaceuticals explained in detail and a wealth of images and clinical cases, the book represents a versatile, comprehensive and practice-oriented guide to PET imaging, pursuing a unique and novel approach to the clinical role of PET tracers. The book’s didactic nature also makes it an invaluable tool for residents in nuclear medicine and radiology, as well as for radiographers and clinicians in radiotherapy, oncology, hematology, cardiology and neurology.
- Contents
- 1. 18F-FDG -- 2. 18F-DOPA -- 3. Lipogenesis Pathway: Radiolabeled Choline -- 4. 18F-FET -- 5. 18F-NaF -- 6. Somatostatin Receptor Analogs (68Ga-DOTATOC, 68Ga-DOTANOC, 68Ga-DOTATATE) -- 7. 64Cu-Radiopharmaceuticals -- 8. Amyloid Imaging -- 9. PET Myocardial Perfusion Imaging: 82Rb -- 10. The Bone Pathway: 223Ra-Dichloride -- 11. 11C-Methionine -- 12. 68Ga-PSMA -- 13. PET Biomarkers for Tau Pathology.
- Format
- e-Book
- Location
- Online
Therapy of Movement Disorders : A Case-Based Approach
https://libcat.nshealth.ca/en/permalink/provcat44393
Stephen G. Reich, Stewart A. Factor, editors.
--Cham:
Humana Press
, c2019.
- Available Online
- View e-Book
- Location
- Online
This case-based text provides treatment approaches to common and uncommon movement disorders. The first two parts of the book are devoted to the wide spectrum of motor and non-motor problems encountered in caring for people with Parkinson’s disease, as well as Parkinsonian syndromes. Next are parts with chapters addressing essential and other tremor disorders followed by management of the various dystonic syndromes and other hyperkinetic disorders including chorea, tics, and myoclonus. Other di…
- Available Online
- View e-Book
- Other Authors
- Reich, Stephen G.
- Factor, Stewart A.
- Responsibility
- Stephen G. Reich, Stewart A. Factor, editors
- Place of Publication
- Cham
- Publisher
- Humana Press
- Date of Publication
- c2019
- Physical Description
- 1 online resource (xxv, 348 p.) : 47 illus., 28 illus. in color
- Series Title
- Current clinical neurology
- ISBN
- 9783319978970
- 9783319978963 (Print ed.)
- 9783319978987 (Print ed.)
- ISSN
- 1559-0585
- Subjects (MeSH)
- Movement Disorders - therapy
- Psychomotor Disorders - therapy
- Abstract
- This case-based text provides treatment approaches to common and uncommon movement disorders. The first two parts of the book are devoted to the wide spectrum of motor and non-motor problems encountered in caring for people with Parkinson’s disease, as well as Parkinsonian syndromes. Next are parts with chapters addressing essential and other tremor disorders followed by management of the various dystonic syndromes and other hyperkinetic disorders including chorea, tics, and myoclonus. Other disorders covered are drug-induced movement disorders, psychogenic movement disorders, Wilson’s disease, hemifacial spasm and more. Authored by experts globally, this practical guide will help physicians, other healthcare professionals and trainees care for patients with a wide spectrum of movement disorder related problems.
- Contents
- Part I. PD: Motor -- 1. Diagnosing Parkinson’s Disease -- 2. Initiating Treatment for Parkinson’s Disease -- 3. Medical Therapy for Fluctuations in Parkinson’s Disease -- 4. Treatment of Levodopa-Induced Dyskinesia in Parkinson’s Disease -- 5. Deep Brain Stimulation for Tremor in Parkinson’s Disease -- 6. Deep Brain Stimulation for Fluctuations and Dyskinesia in Parkinson’s Disease -- 7. Falls in Parkinson’s Disease -- 8. Treatment of Freezing of Gait in Parkinson’s disease -- 9. Treatment of Dysarthria in Parkinson Disease -- 10. Treatment of Dysphagia in Parkinson’s Disease -- 11. Rehabilitation for PD -- Part II. PD Non-Motor -- 12. Treatment of Orthostatic Hypotension in Parkinson’s Disease -- 13. Treatment of Constipation in Parkinson’s Disease -- 14. Treatment of Urinary and Sexual Dysfunction in Parkinson’s Disease -- 15. Treatment of Drenching Sweats in Parkinson’s Disease -- 16. Treatment of Drooling in Parkinson’s Disease -- 17. Treatment of Pain in Parkinson’s Disease -- 18. Treatment of Fatigue in Parkinson’s Disease -- 19. Treatment of Diplopia in Parkinson’s Disease -- 20. Treatment of Insomnia in Parkinson’s Disease -- 21. Treatment of Daytime Sleepiness in Parkinson’s Disease -- 22. Treatment of REM Sleep Behavior Disorder in Parkinson’s Disease -- 23. Mild Cognitive Impairment in Parkinson’s Disease -- 24. Treatment of Dementia in Parkinson’s Disease -- 25. Treatment of Anxiety in Parkinson’s Disease -- 26. Treatment of Depression in Parkinson’s Disease -- 27. Treatment of Hallucinations and Delusions in Parkinson’s Disease -- 28. Treatment of Apathy in Parkinson’s Disease -- 29. Treatment of Impulse Control Disorders and Dopamine Agonist Withdrawal Syndrome in Parkinson’s Disease -- 30. Treatment of Dopamine Dysregulation Syndrome and Impulse Control Disorders in Parkinson’s Disease -- 31. Driving in Parkinson’s Disease -- 32. Treatment of Progressive Supranuclear Palsy -- 33. Treatment of Multiple System Atrophy -- 34. Treatment of Dementia with Lewy Bodies -- 35. Treatment of Corticobasal Syndrome -- 36. Is There Vascular Parkinsonism? -- Part III. Tremor -- 37. Treatment of Essential Tremor: Medical Therapy -- 38. Treatment of Essential Tremor: Surgical Therapy -- 39. Treatment of Orthostatic Tremor -- 40. Treatment of Essential Tremor: Deep Brain Stimulation -- 41. Treatment of Palatal Tremor -- 42. Treatment of Cerebellar Tremor -- 43. Treatment of Holmes Tremor -- Part IV. Dystonia -- 44. Classification of the Dystonias -- 45. Treatment of Blepharospasm -- 46. Treatment of Cervical Dystonia -- 47. Treatment of Oromandibular Dystonia -- 48. Treatment of Laryngeal Dystonia -- 49. Treatment of Dystonic Writers’ Cramp -- 50. Treatment of Musicians’ Dystonia -- 51. Treatment of Generalized Dystonia -- 52. Treatment of Status Dystonicus (Dystonic Storm) -- 53. Treatment of Dystonia: Deep Brain Stimulation -- 54. Treatment of Myoclonic Dystonia -- 55. Treatment of Dopa-Responsive Dystonia -- Part V. Chorea -- 56. Treatment of the Motor Features of Huntington’s Disease -- 57. Treatment of Irritability and Aggression in Huntington’s Disease -- 58. Treatment of Hemiballismus -- 59. Treatment of Sydenham’s Chorea -- Part VI. Tics -- 60. Treatment of Tourette Syndrome: Medical Therapy -- 61. Treatment of Non-Motor Symptoms in Tourette Syndrome -- Part VII. Myoclonus -- 62. Treatment of Post-Hypoxic Myoclonus -- 63. Treatment of Myoclonus in Degenerative Disorders -- Part VIII. Tardive Sybdromes -- 64. Treatment of Tardive Dyskinesia -- 65. Treatment of Tardive Dystonia -- 66. Treatment of Drug-Induced Parkinsonism -- 67. Treatment of Tardive Akathisia -- 68. Treatment of Acute Dystonic Reactions -- 69. Treatment of Neuroleptic Malignant Syndrome -- 70. Treatment of Serotonin Syndrome -- Part IX. Other -- 71. Treatment of Paroxysmal Kinesigenic Dyskinesias -- 72. Treatment of Paroxysmal Nonkinesigenic Dyskinesia -- 73. Treatment of Psychogenic (Functional) Movement Disorders -- 74. Treatment of Wilson Disease -- 75. Treatment of Hemifacial Spasm -- 76. Treatment of Restless Leg Syndrome, Periodic Leg Movements of Sleep -- 77. Treatment of Stiff Person Syndrome.
- Format
- e-Book
- Publication Type
- Case Reports
- Location
- Online
