Assisted Reproductive Technologies and Infectious Diseases : A Guide to Management
https://libcat.nshealth.ca/en/permalink/provcat40157
Andrea Borini, Maria Valeria Savasi, editors.
--Cham:
Springer
, c2016.
- Available Online
- View e-Book
- Location
- Online
This concise and practical book is the first of its kind to examine the use of assisted reproductive technologies (ART) in relation to blood-borne infectious diseases: human immunodeficiency virus (HIV), hepatitis B (HBV) and hepatitis C (HCV). The book opens with a discussion of the impact of these viruses on male and female fertility, followed by specific chapters of each of them, including ART with HIV and HCV serodiscordant couples (where either the male or female is positive) and the detec…
- Available Online
- View e-Book
- Other Authors
- Borini, Andrea
- Savasi, Maria Valeria
- Responsibility
- Andrea Borini, Maria Valeria Savasi, editors
- Place of Publication
- Cham
- Publisher
- Springer
- Date of Publication
- c2016
- Physical Description
- 1 online resource (xiii, 207 p. : 7 illus., 6 illus. in color)
- ISBN
- 9783319301129
- 9783319301105 (print ed.)
- Abstract
- This concise and practical book is the first of its kind to examine the use of assisted reproductive technologies (ART) in relation to blood-borne infectious diseases: human immunodeficiency virus (HIV), hepatitis B (HBV) and hepatitis C (HCV). The book opens with a discussion of the impact of these viruses on male and female fertility, followed by specific chapters of each of them, including ART with HIV and HCV serodiscordant couples (where either the male or female is positive) and the detection and impact of HBV and HCV in human gametes and embryos. An important character on laboratory safety when performing ART with blood-borne viruses follows, and the book concludes with a discussion of ART in austere and resource-poor settings, where these infections are often dominant due to lack of treatment and access to vaccines. Written and edited by an international array of experts in reproductive medicine, Assisted Reproductive Technologies and Infectious Diseases explores questions, techniques, and related issues with the aim of effectively helping clinicians working with serodiscordant couples wishing to have children.
- Contents
- The Impact of Human Immunodeficiency Virus (HIV) and Hepatitis B Virus (HBV) and Hepatitis C Virus (HCV) on Male and Female Fertility -- HBV Virus in the Future -- Reproductive Assistance in HIV Serodiscordant Couples where the Man is Positive -- Reproductive Assistance in HIV Serodiscordant Couples where the Woman is Positive -- The Presence of Hepatitis B and C Virus in Human Gametes and Embryos -- Detection of Hepatitis C Virus in Semen of Infected Men and Reproductive Assistance in HCV Discordant Couples: An Overview -- Laboratory Safety during Assisted Reproduction in Patients with Bloodborne Virus -- Accessibility to Reproductive Assistance in Low-Income Countries.
- Format
- e-Book
- Location
- Online
Biennial Review of Infertility. Volume 3
https://libcat.nshealth.ca/en/permalink/provcat40744
Peter N. Schlegel, Bart C. Fauser, Douglas T. Carrell, Catherine Racowsky, editors.
--New York, NY:
Springer
, c2013.
- Available Online
- View e-Book
- Location
- Online
In this third volume, the Biennial Review of Infertility brings together the most up-to-date research and clinical information on male and female infertility, emerging assisted reproductive techniques, and controversial issues in reproductive medicine. An impressive panel of contributors presents cutting-edge information in a clear and well-balanced manner. This volume includes hot topics in reproductive medicine including age and its impact on fertility, lifestyle factors and reproductive heal…
- Available Online
- View e-Book
- Responsibility
- Peter N. Schlegel, Bart C. Fauser, Douglas T. Carrell, Catherine Racowsky, editors
- Place of Publication
- New York, NY
- Publisher
- Springer
- Date of Publication
- c2013
- Physical Description
- 1 online resource (xviii, 264 p. : 43 illus., 30 illus. in color)
- ISBN
- 9781461471875
- 9781461471868 (print ed.)
- Subjects (MeSH)
- Infertility
- Reproductive Medicine
- Reproductive Techniques, Assisted
- Abstract
- In this third volume, the Biennial Review of Infertility brings together the most up-to-date research and clinical information on male and female infertility, emerging assisted reproductive techniques, and controversial issues in reproductive medicine. An impressive panel of contributors presents cutting-edge information in a clear and well-balanced manner. This volume includes hot topics in reproductive medicine including age and its impact on fertility, lifestyle factors and reproductive health, fertility preservation for cancer patients, reproductive tourism, and a discussion of clinical research design. The expanded section on controversies allows for point/counterpoint discussion between experts with differing opinions on topics like safety of the ICSI procedure and the role of IUI in modern reproductive medicine. Created to provide an ongoing appraisal of current knowledge, the Biennial Review of Infertility stimulates communication amongst all those working to help couples resolve their infertility.
- Contents
- PART I: MALE INFERTILITY -- Supplements to enhance male fertility -- Poor quality ejaculate sperm: do the data support the use of testis sperm? -- The aging male and impact on offspring -- Testosterone replacement therapy in men: effects on fertility and health -- PART II: FEMALE INFERTILITY -- A practical approach to recent advances in ovarian reserve testing -- Maternal age and oocyte aneuploidy: lessons learned from trisomy 21 -- Fertility preservation for cancer patients -- Reproductive surgery and computer-assisted laparoscopy: the new age of subspecialty surgery is here -- PART III: ASSISTED REPRODUCTION TECHNIQUES -- Advances in systems for embryo culture -- Patient tailored approaches to ovarian stimulation in ART -- Cryopreserved oocyte banking: its prospects and promise -- Reproductive tourism -- PART IV: EVOLVING CONTROVERSIES IN CONTEMPORARY REPRODUCTIVE MEDICINE -- Intrauterine insemination: an ineffective treatment -- IUI is a valuable and cost-effective therapy for most couples -- Vitrification of human oocytes and embryos: an overview -- Should we eliminate fresh embryo transfer from ART? -- ICSI is a revolutionary treatment of male infertility that should be employed discriminately and further studied -- The need for long-term follow-up of children conceived through ICSI -- Popularity of ICSI -- PART IV: CLINICAL RESEARCH DESIGN -- Cohort designs: critical considerations for reproductive health.
- Format
- e-Book
- Location
- Online
Biennial Review of Infertility. Volume 4
https://libcat.nshealth.ca/en/permalink/provcat39296
Douglas T. Carrell, Peter N. Schlegel, Catherine Racowsky, Luca Gianaroli, editors.
--Cham:
Springer
, c2015.
- Available Online
- View e-Book
- Location
- Online
Now in its fourth volume, the Biennial Review of Infertility brings together the most up-to-date research and clinical information on male and female infertility, emerging assisted reproductive techniques and evolving controversies in reproductive medicine. An impressive panel of contributors presents cutting-edge information in a clear and well-balanced manner. Volume 4 discusses hot topics in contemporary reproductive medicine, including stem cell technologies for male infertility, the curren…
- Available Online
- View e-Book
- Responsibility
- Douglas T. Carrell, Peter N. Schlegel, Catherine Racowsky, Luca Gianaroli, editors
- Place of Publication
- Cham
- Publisher
- Springer
- Date of Publication
- c2015
- Physical Description
- 1 online resource (xiii, 244 p. : 27 illus., 21 illus. in color)
- ISBN
- 9783319178493
- 9783319178486 (print ed.)
- Subjects (MeSH)
- Infertility
- Reproductive Medicine
- Reproductive Techniques, Assisted
- Abstract
- Now in its fourth volume, the Biennial Review of Infertility brings together the most up-to-date research and clinical information on male and female infertility, emerging assisted reproductive techniques and evolving controversies in reproductive medicine. An impressive panel of contributors presents cutting-edge information in a clear and well-balanced manner. Volume 4 discusses hot topics in contemporary reproductive medicine, including stem cell technologies for male infertility, the current state of ovarian tissue cryopreservation and time-lapse video microscopy of embryos. The expanded section on controversies allows for point/counterpoint discussion between experts with differing opinions on topics like eSET and the use and role of dietary supplements in IVF cycles. Created to provide an ongoing appraisal of current knowledge, the Biennial Review of Infertility stimulates communication amongst all clinicians and researchers working to help couples resolve their infertility.
- Contents
- Part I: Male -- The Epidemiology of Male Infertility -- Vasectomy Reversal or IVF: Analysis of Factors for Success -- Stem Cell Therapies for Male Infertility: Where Are We Now and Where Are We Going? -- Part II: Female -- Insights Into Mechanisms Causing the Maternal Age-induced Decrease in Oocyte Quality -- Endometriosis and Cancer: Is There an Association? -- Ovarian Tissue Cryopreservation: Where Are We Now? -- Part III: ART -- Animal Models for Developing Clinical Lab Procedures -- Current Status of Time-lapse Microscopy for Embryo Selection -- The Ideal Spermatozoon for ART -- Is Acupuncture Associated with Improved IVF Outcomes? -- Dr. Web and the New Generation of ART Patients -- Part IV: Controversies -- Yes, Elective Single Embryo Transfer Should Be Standard of Care -- Klinefelter Syndrome: Early Treatment of the Adolescent is Warranted -- Klinefelter Syndrome: Early Treatment of the Adolescent is Not Warranted -- Are Dietary Supplements Beneficial for IVF Patients?.
- Format
- e-Book
- Location
- Online
Developmental origins of health and disease
https://libcat.nshealth.ca/en/permalink/provcat27252
edited by Peter Gluckman, Mark Hanson.
--Cambridge, UK:
Cambridge University Press
, 2006.
- Available Online
- View e-Book
- Location
- Online
- Available Online
- View e-Book
- Author
- Gluckman, Peter D
- Other Authors
- Hanson, Mark A
- Responsibility
- edited by Peter Gluckman, Mark Hanson
- Place of Publication
- Cambridge, UK
- Publisher
- Cambridge University Press
- Date of Publication
- 2006
- Physical Description
- xvi, 519 p., [6] p. plates
- ISBN
- 6610458057 (electronic bk.)
- Subjects (MeSH)
- Developmental Biology
- Disease Susceptibility
- Prenatal Exposure Delayed Effects
- Disease - etiology
- Contents
- Cover -- Half-title -- Title -- Copyright -- Contents -- List of Contributors -- Preface -- 1 The developmental origins of health and disease: an overview -- REFERENCES -- 2 The developmental origins' hypothesis: epidemiology -- Introduction -- Fetal, infant and childhood growth in relation to health in later life -- Ecological observations pointing to developmental influences on adult health -- Coronary heart disease -- Cohort studies of size at birth and coronary heart disease -- Infant and childhood growth and coronary heart disease -- Size of effects and potential confounding influences -- Stroke, hypertension and cardiovascular function -- Hypertension and blood pressure -- Mechanisms underlying developmental effects on hypertension and raised blood pressure -- Cardiovascular structure and function -- Serum cholesterol and blood clotting -- Type 2 diabetes and the metabolic syndrome -- Size at birth and type 2 diabetes -- Insulin resistance and the metabolic syndrome -- Obesity and the adiposity rebound -- Musculoskeletal health -- Respiratory health and atopy -- Cognitive function and mental health -- Brain growth and cognitive function in childhood and old age -- Schizophrenia and mood disorders -- Maternal influences on development and offspring health -- Periconceptional influences and the early trajectory of fetal growth -- Transgenerational effects -- Maternal influences on placental size and transfer capabilities -- Maternal diet and body composition -- Prevention of adult degenerative disease -- Conclusion -- REFERENCES -- 3 The conceptual basis for the developmental origins of health and disease -- Introduction -- Developmental disruption and developmental plasticity -- Adaptive responses during development -- Explanations of the developmental origins of adult disease -- The 'thrifty genotype' hypothesis -- The 'thrifty phenotype' hypothesis -- Gene...environment interactions and the explanation of the DOHaD paradigm -- The role of catch-up growth -- Constraint of fetal growth -- Match...mismatch, PARs and DOHaD: towards a conceptual synthesis -- ACKNOWLEDGMENTS -- REFERENCES -- 4 The periconceptional and embryonic period -- Introduction -- Embryos and epigenesis -- Embryo metabolism in response to environmental conditions -- Signal transduction and embryo developmental potential -- Gene expression changes in embryos in response to environment -- Embryo environment and cellular proliferation -- From embryo plasticity to fetal physiology -- Conclusions -- ACKNOWLEDGMENTS -- REFERENCES -- 5 Epigenetic mechanisms -- Introduction -- The nature of epigenetic information -- DNA methylation -- Epigenetic information of chromatin -- Chromatin remodelling -- Covalent histone modifications -- Epigenetics and development -- Clearing and establishing epigenetic marks during development -- Parental imprinting -- X-chromosome inactivation -- Epigenetics and nuclear cloning -- Epigenetic modifications are influenced by the environment -- Epigenetics and disease -- Defects in DNA methylation as a cause of disease -- Defects in histone modifications and nucleosome remodelling
- Format
- e-Book
- Location
- Online
Emerging Topics in Reproduction. Volume 5
https://libcat.nshealth.ca/en/permalink/provcat42580
Douglas T. Carrell, Catherine Racowsky, Peter N. Schlegel, Alan H. DeCherney, editors.
--Cham:
Springer
, c2018.
- Available Online
- View e-Book
- Location
- Online
Previously known as Biennial Review of Infertility, the fifth installment in this series brings together the most current research and clinical evidence on male and female infertility, emerging assisted reproductive technologies (ART) and evolving controversies in reproductive medicine. In this latest volume, parts one and two discuss recent developments in male and female infertility respectively, including fertility preservation in the male adolescent cancer patient, the clinical relevance of…
- Available Online
- View e-Book
- Responsibility
- Douglas T. Carrell, Catherine Racowsky, Peter N. Schlegel, Alan H. DeCherney, editors
- Former Title
- Biennial review of infertility
- Place of Publication
- Cham
- Publisher
- Springer
- Date of Publication
- c2018
- Physical Description
- 1 online resource (xiii, 243 p.) : 39 illus., 21 illus. in color
- ISBN
- 9783319908236
- 9783319908229 (print ed.)
- 9783319908243 (print ed.)
- Subjects (MeSH)
- Infertility
- Reproductive Techniques, Assisted
- Reproductive Medicine
- Specialty
- Reproductive Medicine
- Abstract
- Previously known as Biennial Review of Infertility, the fifth installment in this series brings together the most current research and clinical evidence on male and female infertility, emerging assisted reproductive technologies (ART) and evolving controversies in reproductive medicine. In this latest volume, parts one and two discuss recent developments in male and female infertility respectively, including fertility preservation in the male adolescent cancer patient, the clinical relevance of sperm RNA, the management of subclinical hypothyroidism, and the effects of endocrine-disrupting chemicals. Part three covers the latest in ART, such as evidence-based morphological approaches for embryo selection and culturing human embryos. The final section highlights controversies in reproductive medicine, including the use of preimplantation genetic screening (PGS) and blastocyst transfer, as well as the ethics surrounding a maximum BMI for IVF. Providing an ongoing appraisal of current knowledge, and featuring contributions from leading experts in the field, Emerging Topics in Reproduction, Volume 5 is a worthy addition to the series and an ideal resource on the latest topics for reproductive medicine and REI specialists, OB-GYNS, andrologists, and any clinician working with infertility.
- Contents
- Part I: Male -- TESE for Cryptozoospermia with Normal Sperm DNA Fragmentation -- The Argument for Varicocele Repair in Non-Obstructive Azoospermia -- Current and Future Perspectives on Sperm RNAs -- Male Infertility as a Marker of Future Health -- Fertility Preservation in the Male Adolescent Patient -- Part II: Female -- Advanced Imaging Techniques Used in the Infertile Female -- Treatment of Subclinical Hypothyroidism in the Infertile Female -- Endocrine-Disrupting Chemicals and Female Infertility -- Part III: ART [Assisted Reproductive Technologies] -- Is There an Optimum System for Culturing Human Embryos?- Evidence-Based Approaches to Embryo Selection by Morphology and Kinetics -- Part IV: Controversies -- Is It Good Practice/Ethical to Set a Max BMI Before IVF? -- Are We Closer to "Freeze-All" for ART? -- Preimplantation Genetic Screening: Not for Everyone -- Should All Patients Undergo Blastocyst Transfer? No.
- Format
- e-Book
- Location
- Online
The Ethics of Embryo Adoption and the Catholic Tradition : Moral Arguments, Economic Reality and Social Analysis
https://libcat.nshealth.ca/en/permalink/provcat40573
Sarah-Vaughan Brakman, Darlene Fozard Weaver, editors.
--Dordrecht:
Springer
, c2007.
- Available Online
- View e-Book
- Location
- Online
At last, a comprehensive collection of essays that examines and advances ethical evaluations of the controversial and increasingly popular practice of embryo adoption. In the United States alone, 400,000 frozen embryos created for in vitro fertilization exist but are no longer desired for that purpose. What are we morally obliged or permitted to do about these "spare" embryos? More of their genetic parents are considering donating these embryos to others to gestate and raise. This practice is p…
- Available Online
- View e-Book
- Other Authors
- Brakman, Sarah-Vaughan
- Weaver, Darlene Fozard
- Responsibility
- Sarah-Vaughan Brakman, Darlene Fozard Weaver, editors
- Place of Publication
- Dordrecht
- Publisher
- Springer
- Date of Publication
- c2007
- Physical Description
- 1 online resource (x, 326 p.)
- Series Vol.
- 95
- v. 6
- Series Title
- Philosophy and medicine
- Catholic studies in bioethics
- ISBN
- 9781402062117
- 9781402062100 (print ed.)
- ISSN
- 0376-7418
- Subjects (MeSH)
- Adoption
- Catholicism
- Embryo Disposition - ethics
- Embryo Transfer - ethics
- Abstract
- At last, a comprehensive collection of essays that examines and advances ethical evaluations of the controversial and increasingly popular practice of embryo adoption. In the United States alone, 400,000 frozen embryos created for in vitro fertilization exist but are no longer desired for that purpose. What are we morally obliged or permitted to do about these "spare" embryos? More of their genetic parents are considering donating these embryos to others to gestate and raise. This practice is politically volatile (figuring in debates about embryonic stem cells) and medically and morally complex. At the present time within the Roman Catholic Church there is no official teaching on embryo adoption. Catholic ethical analyses grapple with the way embryo adoption comports with respect for embryonic human life yet challenges Catholic moral critiques of assisted reproductive technologies. This volume brings together leading philosophers and theologians to engage Catholic debates about embryo adoption in an interactive format. The editors, a philosopher bioethicist and a moral theologian, provide a helpful overview of the practice and the arguments surrounding embryo adoption. They engage neglected Catholic ethical resources and issues to advance the current debate and chart new directions in Catholic moral thinking about this intriguing practice. The volume also includes a description of embryo adoption from a physician practitioner along with reflections from a couple who successfully adopted an embryo.
- Contents
- Part I. The Morality of Embryo Adoption -- Introduction: The Ethics of Embryo Adoption and the Catholic Tradition -- Arguments Against -- Heterologous Embryo Transfer: Metaphor and Morality -- Human Embryo Transfer and the Theology of the Body -- On the Moral Objectionability of Human Embryo Adoption -- Arguments For -- Could Human Embryo Transfer Be Intrinsically Immoral? -- Ethical Considerations in Defense of Embryo Adoption -- Real Mothers and Good Stewards: The Ethics of Embryo Adoption -- Part II. The Debate Engaged -- Embryo Adoption Theologically Considered: Bodies, Adoption, and the Common Good -- From Rescuing Frozen Embryos to Respecting the Limits of Nature: Reframing the Embryo Adoption Debate -- Embryo Adoption? An Egalitarian Perspective -- A Protestant View: The Ethics of Embryo Adoption and the Catholic Tradition -- Part III. Morality in the Practice -- Development of the National Embryo Donation Center -- An Embryo Adoptive Father's Perspective -- An Embryo Adoptive Mother's Perspective -- Ethical and Religious Directives for a Catholic Embryo Adoption Agency: A Thought Experiment -- Embryo Adoption and the Law -- Artificial Wombs and Embryo Adoption.
- Format
- e-Book
- Location
- Online
Frontiers in Gynecological Endocrinology. Volume 9, Endometriosis Pathogenesis, Clinical Impact and Management
https://libcat.nshealth.ca/en/permalink/provcat46491
Andrea R. Genazzani, Michelle Nisolle, Felice Petraglia, Robert N. Taylor, editors.
--Cham:
Springer
, c2021.
- Available Online
- View e-Book
- Access
- NEW Springer 2021
- Location
- Online
This volume focuses on endometriosis from its pathogenesis and the importance of the early diagnosis to treatment, throughout all aspects of femininity that this disease affects, impacting health and quality of life. It also covers treatment strategies for the pain and for the disease management according to the age and needs of the patient, from adolescence to menopause, passing through the fertile age and the consequences that this disease can have on fertility and pregnancy. This book is a u…
- Available Online
- View e-Book
- Responsibility
- Andrea R. Genazzani, Michelle Nisolle, Felice Petraglia, Robert N. Taylor, editors
- Place of Publication
- Cham
- Publisher
- Springer
- Date of Publication
- c2021
- Physical Description
- 1 online resource (viii, 166 p.) : 20 illus., 14 illus. in color
- ISBN
- 9783030578664
- 9783030578657 (Print ed.)
- 9783030578671 (Print ed.)
- 9783030578688 (Print ed.)
- ISSN
- 2197-8735
- Subjects (MeSH)
- Endometriosis - diagnosis
- Endometriosis - therapy
- Specialty
- Endocrinology
- Gynecology
- Abstract
- This volume focuses on endometriosis from its pathogenesis and the importance of the early diagnosis to treatment, throughout all aspects of femininity that this disease affects, impacting health and quality of life. It also covers treatment strategies for the pain and for the disease management according to the age and needs of the patient, from adolescence to menopause, passing through the fertile age and the consequences that this disease can have on fertility and pregnancy. This book is a useful, clear and up-to-date tool for gynecologists, gynecological surgeons, reproductive medicine and general practitioners and is an important source of information to face this more and more frequent and devastating disease.
- Contents
- 1. Endocrine disruptors and risk of endometriosis -- 2. Metabolomic characteristics in endometriosis patients -- 3. Can we diagnose early endometriosis with ultrasound rather than laparoscopy? -- 4. Neurotrophins and cytokines in endometriosis pain -- 5. Endometriosis induced pain: the treatment strategy -- 6. Management of endometriosis in teenagers -- 7. The etonogestrel contraceptive implant as a therapy for endometriosis -- 8. Impact of endometrioma surgery on ovarian reserve -- 9. What is the place of surgery of deep endometriosis in infertile and pelvic pain patients? -- 10. Endometriosis and Infertility: surgery and IVF: when, why and outcomes -- 11. ART and endometriosis : problems and solutions -- 12. Morphokinetics in embryos from patients with endometriosis -- 13. Endometriosis and cancer: prevention and diagnosis -- 14. Medical management of endometriosis, present and future with special reference to MHT in the patient previously diagnosed with endometriosis -- 15. Endometriosis and menopause: realities and management.
- Access
- NEW Springer 2021
- Format
- e-Book
- Location
- Online
Gonadal Tissue Cryopreservation in Fertility Preservation
https://libcat.nshealth.ca/en/permalink/provcat40418
Nao Suzuki, Jacques Donnez, editors.
--Tokyo:
Springer Japan
, c2016.
- Available Online
- View e-Book
- Location
- Online
This book is a practical guide to the cryopreservation and transplantation of oocytes, embryos, and ovarian and testicular tissue for fertility preservation. Illustrated with a wealth of figures and photos, it provides updated techniques for clinicians, technicians, and researchers. This book also gives insights into in vitro activation (IVA), in vitro growing (IVG), and in vitro maturation (IVM), with both basic research and future directions. These techniques combined with cryopreservation wi…
- Available Online
- View e-Book
- Other Authors
- Suzuki, Nao
- Donnez, Jacques
- Responsibility
- Nao Suzuki, Jacques Donnez, editors
- Place of Publication
- Tokyo
- Publisher
- Springer Japan
- Date of Publication
- c2016
- Physical Description
- 1 online resource (viii, 192 p. : 33 illus., 32 illus. in color)
- ISBN
- 9784431559634
- 9784431559610 (print ed.)
- Subjects (MeSH)
- Cryopreservation
- Fertility Preservation
- Gonads
- Infertility - prevention & control
- Neoplasms - therapy
- Abstract
- This book is a practical guide to the cryopreservation and transplantation of oocytes, embryos, and ovarian and testicular tissue for fertility preservation. Illustrated with a wealth of figures and photos, it provides updated techniques for clinicians, technicians, and researchers. This book also gives insights into in vitro activation (IVA), in vitro growing (IVG), and in vitro maturation (IVM), with both basic research and future directions. These techniques combined with cryopreservation will improve the chances of reproduction. Cryopreservation is essential to protect fertility in cancer patients who undergo treatment with radioiodine or chemotherapy, which may cause damage to their reproductive organs, and also for primary ovarian insufficiency patients. The book also includes a chapter on the risk of the presence of malignant cells in ovarian tissue. Both editors are pioneering researchers in this field.
- Contents
- 1. Oocytes Cryopreservation -- 2. Controlled Ovarian Stimulation Protocols in Cancer Patients -- 3. Embryo Cryopreservation in Breast Cancer Patients -- 4. Ovarian Tissue Cryopreservation: Slow Freezing -- 5. Ovarian Tissue Cryopreservation: Ovarian Cortical Tissue Vitrification -- 6. Ovarian Tissue Freezing and Transplantation: Current Status -- 7. Heterotopic Ovarian Tissue Transplantation -- 8. Sperm Cryopreservation -- 9. Testicular Tissue Cryopreservation -- 10. IVA and Ovarian Tissue Cryopreservation -- 11. Risk of Transferring Malignant Cells with Transplanted Frozen-Thawed Ovarian Tissue -- 12. Artificial Ovary.
- Format
- e-Book
- Location
- Online
Human Embryo Transfer
https://libcat.nshealth.ca/en/permalink/provcat39497
Gautam N. Allahbadia, Claudio F. Chillik, editors.
--New Delhi:
Springer India
, c2015.
- Available Online
- View e-Book
- Location
- Online
This concise work on embryo transfer is yet another contribution to the persevering effort to disseminate latest information on the science and skill of performing a traumatic and successful embryo transfer. It is the most critical culmination of the assisted reproductive technology (ART) stimulation cycle, and a rate-limiting step in dictating the success of treatment. The well-worded chapters draw the reader's attention to significant aspects before initiating the actual embryo transfer, such…
- Available Online
- View e-Book
- Other Authors
- Allahbadia, Gautam N
- Chillik, Claudio F
- Responsibility
- Gautam N. Allahbadia, Claudio F. Chillik, editors
- Place of Publication
- New Delhi
- Publisher
- Springer India
- Date of Publication
- c2015
- Physical Description
- 1 online resource (xiv, 96 p. : 12 illus., 7 illus. in color)
- ISBN
- 9788132211150
- 9788132211143 (print ed.)
- Subjects (MeSH)
- Embryo Transfer
- Reproductive Techniques, Assisted
- Abstract
- This concise work on embryo transfer is yet another contribution to the persevering effort to disseminate latest information on the science and skill of performing a traumatic and successful embryo transfer. It is the most critical culmination of the assisted reproductive technology (ART) stimulation cycle, and a rate-limiting step in dictating the success of treatment. The well-worded chapters draw the reader's attention to significant aspects before initiating the actual embryo transfer, such as possible causes of failure at the embryo transfer stage, uterine evaluation, mock embryo transfer (ET), experience of the physician, and the use of ultrasound-guidance to monitor ET. The protocol for difficult transfers, variables that affect the success of ET, and the influence of the catheter used for ET have also been dealt with. The unique feature of this book is its pragmatic approach that can translate into solutions to the numerous frustrating ART failures that more often than not, may be attributed to an inefficient ET procedure. It helps the reader understand the integrity of embryo transfer, unravel its obvious simplicity and bridge the success between the several steps of ART. By highlighting the impeding problems associated with ET procedure and providing valid, scientific solutions, this stimulating edition will help the readers improve the ART success rates in their clinical practice.
- Contents
- Evaluation of the uterus prior to embryo transfer -- Trial Embryo Transfer (Mock Transfer) -- Does the Experience of the Provider Affect Pregnancy Rates After Embryo Transfer? -- Ultrasound-Guided ETs or Clinical Touch ETs? -- Variables That Affect a Successful Embryo Transfer -- Management of Difficult Embryo Transfers -- Facts and Myths of Embryo Transfer -- Uterine Contractility and Embryo Transfer -- Embryo Transfer Media and Catheters -- Is There A Role for Tubal Transfers? -- Loading and Expulsion of Embryos.
- Format
- e-Book
- Location
- Online
Human Fetal Growth and Development : First and Second Trimesters
https://libcat.nshealth.ca/en/permalink/provcat39764
Niranjan Bhattacharya, Phillip G. Stubblefield, editors.
--Cham:
Springer
, c2016.
- Available Online
- View e-Book
- Location
- Online
This book addresses the complexities of growth and maturation, structural and functional developments as well as differentiations of the human fetus. Many of the authors are part of the Institute of Post-Graduate Medical Education and Research (IPGMER), whose research into human foetuses has generated many studies on the fetus, ranging from the morphometry and growth of organs, the DNA and RNA to different proteins and enzymes. The data collected over many decades provides a deep insight into t…
- Available Online
- View e-Book
- Other Authors
- Bhattacharya, Niranjan
- Stubblefield, Phillip G
- Responsibility
- Niranjan Bhattacharya, Phillip G. Stubblefield, editors
- Place of Publication
- Cham
- Publisher
- Springer
- Date of Publication
- c2016
- Physical Description
- 1 online resource (xxxv, 593 p. : 162 illus., 122 illus. in color)
- ISBN
- 9783319148748
- 9783319148731 (print ed.)
- Subjects (MeSH)
- Embryonic Development
- Fetal Development
- Pregnancy Trimester, First
- Pregnancy Trimester, Second
- Abstract
- This book addresses the complexities of growth and maturation, structural and functional developments as well as differentiations of the human fetus. Many of the authors are part of the Institute of Post-Graduate Medical Education and Research (IPGMER), whose research into human foetuses has generated many studies on the fetus, ranging from the morphometry and growth of organs, the DNA and RNA to different proteins and enzymes. The data collected over many decades provides a deep insight into the growth and development of the human fetus, its aberrations and implications for understanding the intricacies and complexities of growth regulation up to twenty weeks of gestation. The editors bring together this extensive research from IPGMER, in addition to astute and precision research from global leaders in the fields of genetics, proteomics stem cell biology, endocrinology and molecular biology. Human Fetal Growth and Development: First and Second Trimesters is a pioneering work, stimulating further allied research in this area, and will be of interest to gynecologists, pediatricians, obstetricians, neonatologists, endocrinologists, reproductive and molecular biologists, and all students of medicine at all levels.
- Contents
- Part 1. Introduction -- 1. What is Fetal Growth -- 2. Vaccination of the Unborn: A Perspective -- 3. Understanding the Growth of the Fetus in Utero from the Immunologist's Angle -- 4. Intraamniotic Antigen and Disruption of Human Fetal Growth: A Study from 1978-2002 with Subsequent Follow Up -- 5. Foetal Growth and Development in the First Two Trimesters -- Part 2. Structural and Functional Fetal Development up to Second Trimester -- 6. Anthropometric Measurement of the Human Fetus -- 7. Human Fetal Carbohydrate Metabolism -- 8. Mucopolysaccharides, Water and Electrolytes of Human Fetal Organs -- 9. Urea Biosynthesis in Human Fetal Liver -- 10. Mechanism of Rejection of Human Fetal Adrenal Cortex -- 11. Development of Human Fetal Brain -- 12. Lipid Metabolism in the Human Fetus Development -- Part 3. Gene and Human Fetal Development up to Second Trimester -- 13. Gene Regulatory Networks and Epigenetic Modifications in Cell Fate Decisions During the Early Embryonic Development -- 14. Personal Human Life Begins with the Formation of Adult Type Hippocampus at 13th Week of Development -- 15. Dependence of Fetal Hairs and Sebaceous Glands on Fetal Adrenal Cortex and Possible Control from Epidermal Merkel Cells and Adrenal Medulla -- 16. Theoretical Postulation of the Embryological Basis of the Virgin Birth and Role of Embryonic Stem Cells Localized out of the Embryo -- 17. Aneuploidy in Human Preimplantation Embryos -- 18. The Potential Impact of Maternal Milk Consumption during Pregnancy on mTORC1-Driven Fetal Growth -- 19. Genetic Disease Specific Human Embryonic Stem Cell Lines -- Part 4. Impact of Stem Cell on Growth and Development of Human Fetus -- 20. Stem Cells in Growth and Development of the Human Fetus -- 21. The Mystery of the Survival of the Human Fetus in Utero -- Part 5. Fetal Endocrine Development up to Second Trimester -- 22. Glucose Metabolism in Foetus and Its Relationship with Foetal Insulin -- 23. Growth and Maturation of the Human Fetal Endocrine System Up to Twenty Four Weeks of Gestation -- Partá6. Fetal Immune Development: Up To Second Trimester.-á24. Development of Human Immune System in First and Second Trimester -- Part 7. Fetal Hepatic Development: Up To Second Semester -- 25. Growth and Development of Human Liver and Its Future Implications -- 26. Embryonic Development of Liver and its Future Implications -- Part 8. Fetal Cardiovascular Development: Up To Second Semester -- 27. Embryological Basis for Vascular Anomalies -- 28. Cardio Vascular Developmental Abnormality of the Human Fetus Appearing within Second Trimester: Detection and Treatment -- Part 9. Fetal Neurological Development: Up To Second Trimester and Its Implication in Adult Neurodegenerative Disease -- 29. Implications of Fetal Development and Neurodegeneration in Adult Life -- Part 10. Fetal Neuropsychiatric Development: Up To Second Trimester -- 30. Very Low Birth Weight Babies and Their Mental Health Outcome -- Part 11. Fetal Nephrological Development: Up To Second Trimester -- 31. Development of Renal Tissues in First Twenty Weeks -- Part 12. Fetal Haematological Development -- 32. Development of Heamopoiesis System Before Second Trimester of Pregnancy -- Part 13. Pharmacological Implication of Fetal Development: Up To Second Trimester -- 33. Liabilities of Fetus: As a Patient -- 34. Fetus as a Patient During the First and Second Trimester of Growth and Development -- 35. Structural and Functional Developmental Perspectives of the Placental Barrier and its Role in the Fetal Development During the 1st and 2nd Trimester -- Part 14. Surgical Implications of Fetal Development: Up To Second Trimester -- 36. Surgery of the Unborn/Fetal Surgery -- 37. Reflections on Reality: Towards Scarless Healing- D©j©á Vu -- Part 15. Fetal Growth and Adult Life Implications -- 38. Implications of Gross IUGR in Adult Life with Respect to Some Major Diseases -- Part 16. Understanding Fetal Growth from the Perspective of Alternative Medicine -- 39. Growth and Development of the Human Fetus Up to 2nd Trimester: A Perspective of Traditional Chinese Medicine -- 40. Perspectives of Tribal Medicine During the First 6 Months of Pregnancy -- 41. General Perspectives and Applications of Unani Medicine in Pregnancy up to 2nd Trimester -- 42. Applications of Traditional Chinese Medicine Concpts in the Safety and Development of the Fetus During The 1st and 2nd Trimesters of Pregnancy -- 43. General Perspectives of Homeopathic Medicine During the First and Second Trimester of Pregnancy -- 44. Ayurvedic Perspective of the Pregnancy and Fetal Development During the First and Second Trimesters -- Part 17. Miscellaneous.-á45. Problems of Prematurity -- 46. Problms of Extreme Prematurity -- 47. Sequencing of Naturally Aborted Human Fetuses: A Resource for New Knowledge -- Part 18. Ethics and Human Fetal Tissue Research -- 48. Ethics Pertaining to the Use of Aborted Human Tissues for Research and Therapeutic Purposes.
- Format
- e-Book
- Location
- Online
Human Gametes and Preimplantation Embryos : Assessment and Diagnosis
https://libcat.nshealth.ca/en/permalink/provcat40726
David K. Gardner, Denny Sakkas, Emre Seli, Dagan Wells, editors.
--New York, NY:
Springer
, c2013.
- Available Online
- View e-Book
- Location
- Online
In recent years, the advancing science and increasing availability of assisted reproduction have given new hope to infertile couples. However, the use of IVF and ART has also led to marked increases in the number of multiple-infant live births. This poses a public health concern, as these neonates have a higher rate of pre-term delivery, compromising their survival chances and increasing their risk of lifelong disability. By optimizing the selection of gametes and embryos with high probabilitie…
- Available Online
- View e-Book
- Other Authors
- Gardner, David K
- Sakkas, Denny
- Seli, Emre
- Wells, Dagan
- Responsibility
- David K. Gardner, Denny Sakkas, Emre Seli, Dagan Wells, editors
- Place of Publication
- New York, NY
- Publisher
- Springer
- Date of Publication
- c2013
- Physical Description
- 1 online resource (xv, 306 p. : 64 illus., 48 illus. in color)
- ISBN
- 9781461466512
- 9781461466505 (print ed.)
- Subjects (MeSH)
- Blastocyst
- Cell Survival
- Embryo Transfer
- Fertilization in Vitro
- Germ Cells - growth & development
- Preimplantation Diagnosis
- Reproductive Techniques, Assisted
- Abstract
- In recent years, the advancing science and increasing availability of assisted reproduction have given new hope to infertile couples. However, the use of IVF and ART has also led to marked increases in the number of multiple-infant live births. This poses a public health concern, as these neonates have a higher rate of pre-term delivery, compromising their survival chances and increasing their risk of lifelong disability. By optimizing the selection of gametes and embryos with high probabilities of implantation, it is possible to reduce the number of embryos transferred and, by extension, the number of high-risk multiple gestations, while maintaining or increasing pregnancy rates. Human Gametes and Preimplantation Embryos: Assessment and Diagnosis provides a broad yet concise overview of established and developing methodologies for assessment of gamete and embryo viability in assisted reproduction. This book elucidates the best practices for precisely selecting viable specimens based on morphology and cleavage rate and covers the spectrum of emerging adjunctive technologies for predicting reproductive potential. The authors present their extensive knowledge of "omics" approaches (genomics, transcriptomics, proteomics, and metabolomics), with unbiased delineation of the associated advantages and potential pitfalls. This valuable clinical resource is well suited to infertility specialists, Ob/Gyn physicians, IVF laboratory technicians, and researchers in the fields of embryology and reproductive medicine.
- Contents
- Current Practices and Regulations for Embryo Transfer Worldwide: Implications on IVF Outcome -- Analysis of the Zona Pellucida as an Indicator of Oocyte Developmental Potential -- Morphological Assessment of Oocytes, Pronuclear and Cleavage Stage Embryos -- Morphological Assessment of Blastocyst Stage Embryos: Types of Grading Systems and Their Reported Outcomes -- Real Time Imaging Strategies to Improve Morphological Assessment -- Limitations and Benefits of Morphologic Embryo Assessment Strategies: How Far Can Morphological Assessment Go in the Identification of Viable Embryos? -- Sperm Morphologic Characteristics and Their Impact on Embryo Quality and Pregnancy Outcome -- Objective Biomarkers of Sperm Development and Fertility: Assessment of Sperm-Zona Pellucida Binding Ability and Hyaluronic Acid Mediated Selection of Sperm for ICSI Fertilization -- Selecting the Best Sperm and Its Implications in Clinical Practice -- The Origins of Aneuploidy in Human Embryos -- Preimplantation Genetic Screening and Diagnosis Using Fluorescent In Situ Hybridization (FISH) -- Single Nucleotide Polymorphisms and Next Generation Sequencing -- Use of Comparative Genomic Hybridization (CGH) and Microarray-CGH for Preimplantation Genetic Screening -- Quantitative SNP Array and Real-Time PCR Based Human Preimplantation Embryo Aneuploidy Screening -- Regulation of Gene Expression in the Oocyte and Early Embryo: Implications for Transcriptomic and Proteomic Embryo Assessment -- Transcriptomics Technology: Promise and Potential Pitfalls -- Transcriptomic Analysis of Cumulus and Granulosa Cells as a Marker of Embryo Viability -- Mass Spectrometry, Proteomics and the Study of Sperm Cell Biology -- Proteomic Analysis of Embryo Viability -- Metabolism of the Viable Human Embryo -- Analysis of Respiration as an Indicator of Oocyte and Embryo Developmental Potential -- Mitochondrial Activity as a Biomarker of Gamete and Embryo Health -- Carbohydrate Analysis and Embryo Viability -- Identification of Viable Embryos by Non-invasive Measurement of Amino Acids in Culture Media -- Metabolomic Profiling of Embryos Using Spectroscopy -- Microfluidic Devices for the Analysis of Gamete and Embryo Physiology.
- Format
- e-Book
- Location
- Online
In Vitro Fertilization : A Textbook of Current and Emerging Methods and Devices
https://libcat.nshealth.ca/en/permalink/provcat44366
Zsolt Peter Nagy, Alex C. Varghese, Ashok Agarwal, editors.
(Second edition)
--Cham:
Springer
, c2019.
- Available Online
- View e-Book
- Location
- Online
Now in its revised and expanded second edition - including over 20 new chapters - this comprehensive textbook remains a unique and accessible description of the current and developing diagnostic and treatment techniques and technologies comprising in vitro fertilization (IVF). Arranged thematically in sections, each chapter covers a key topic in IVF in a sensible presentation. Parts one and two describe the planning, design and organization of an ART unit and IVF laboratory and equipment and sy…
- Available Online
- View e-Book
- Other Authors
- Nagy, Zsolt Peter
- Varghese, Alex C.
- Agarwal, Ashok
- Responsibility
- Zsolt Peter Nagy, Alex C. Varghese, Ashok Agarwal, editors
- Edition
- Second edition
- Place of Publication
- Cham
- Publisher
- Springer
- Date of Publication
- c2019
- Physical Description
- 1 online resource (xxii, 962 p.) : 213 illus., 198 illus. in color
- ISBN
- 9783319430119
- 9783319430102 (Print ed.)
- 9783319430126 (Print ed.)
- Subjects (MeSH)
- Clinical Laboratory Techniques
- Fertilization in Vitro - instrumentation
- Fertilization in Vitro - methods
- Specialty
- Reproductive Medicine
- Abstract
- Now in its revised and expanded second edition - including over 20 new chapters - this comprehensive textbook remains a unique and accessible description of the current and developing diagnostic and treatment techniques and technologies comprising in vitro fertilization (IVF). Arranged thematically in sections, each chapter covers a key topic in IVF in a sensible presentation. Parts one and two describe the planning, design and organization of an ART unit and IVF laboratory and equipment and systems, respectively. The sections that follow provide detailed descriptions of IVF techniques, embryo culture methods, sperm processing and selection, insemination procedures, micromanipulation, embryo evaluation, cryopreservation, and embryo transfer. Concluding sections address issues of management and regulation of ART labs across the globe, as well as special topics and emerging techniques and devices. Chapter authors, all experts in the field, contribute their expertise from around the world. With the addition of learning key points and review questions at the beginning and end of each chapter, this new edition of In Vitro Fertilization is a readily accessible, high quality instructional resource for reproductive medicine trainees at all levels. Practicing reproductive endocrinologists, urologists, and embryologists also will find value in the book, as will infertility researchers.
- Contents
- Journey of Human Gametes In Vitro: 1978 to 2018 -- I. Setting Up an ART Unit: Planning, Design and Organization -- Setting up an ART Unit - Planning, Design and Construction -- Building the Laboratory -- Air Quality Management -- Organization And Workflow In A Fertility Clinic -- Risk and Safety in the IVF Clinic -- Control of Variables -- Daily, Weekly, and Regular Preparations for the IVF Laboratory -- II. IVF Laboratory Equipment and Culture Systems -- Essential Instruments and Disposable Supplies for an IVF Laboratory -- Co2 and Low-O2 Incubators -- What to Consider When Selecting a LAF, Class II Cabinet or Isolette for Your ART Program? -- Culture Media in IVF: Decisions for the Laboratory -- III. Oocyte Preparation for IVF/ICSI -- Assessment Of Oocyte Quality -- Oocyte Denuding -- IV. Embryo Culture Methods -- Interrupted or Uninterrupted Culture to the Blastocyst Stage in a Single Medium -- Sequential Media for Human Blastocyst Culture -- In Vitro Maturation of Human Oocytes -- Design and Development of Simplified, Low Cost Technologies for Clinical IVF: Applications in High and Low Resource Settings -- In Vitro Culture of Oocytes and Embryos with Micro-vibration: “Naturalization” of Routine IVF Procedure -- Microfluidics for Gamete Manipulation and Embryo Culture -- Time-Lapse Microscopy for Embryo Culture and Selection -- V. Sperm Assessment, Processing and Selection -- Sperm Assessment: Traditional Approaches and Their Indicative Value -- Sperm Assessment: Novel Approaches and Their Indicative Value -- Assessment of Sperm Chromatin Damage by TUNEL Method Using Bench Top Flow Cytometer -- Sperm Processing in ART -- PESA/MESA/TESA/TESE Sperm Processing -- Processing Sperm Samples in HIV-Positive Patients -- An Emerging Medical Device: Electrophoretic Sperm Separation -- Magnetic Activated Cell Sorting of Human Spermatozoa -- VI. Insemination Procedures -- Intrauterine Insemination -- Conventional IVF Insemination -- Intra-Cytoplasmic Sperm Injection -- ntracytoplasmic Morphologically Selected Sperm Injection -- Intracytoplasmic Morphologically Selected Sperm Injection -- Oocyte Activation Deficiency and Advances to Overcome -- VII. Micromanipulators and Micromanipulation -- Hydraulic Manipulators for ICSI -- Research Instruments Micromanipulation Systems -- Eppendorf Micromanipulator: Setup and Operation of Electronic Micromanipulators.-Oocyte Treatment and Preparation for Microinjection -- Piezo-ICSI -- VIII. Embryo Evaluation, Grading, and Assisted Hatching -- Traditional Embryo Morphology Evaluation: From the Zygote to the Blastocyst Stage -- Predicting Embryo Implantation Potential Using Video Monitoring By the Embryoscope Time-Lapse System -- Predicting Embryo Developmental Potential and Viability Using Automated Time-Lapse Analysis -- Proteomics and Metabolomics -- Amino Acid Turnover as a Biomarker of Embryo Viability -- Microfluidics and Microanalytics to Facilitate Quantitative Assessment of Human Embryo Physiology -- Assisted Hatching of Human Embryos for Successful Implantation -- IX. Biopsy Procedures on Oocytes and Embryos -- Polar Body Biopsy -- Cleavage-Stage Embryo Biopsy -- Current and Novel Methods for Chromosome Testing -- Embryo Biopsy for PGD: Current Perspective -- X. Cryopreservation -- Sperm Cryopreservation -- Technologies of Cryoprotectant-free Vitrification of Human Spermatozoa: Asepticity as Criterionn of Effectiveness -- Slow Freezing of Oocytes -- Vitrification: Methods Contributing to Successful Cyopreservation Outcomes -- Oocyte Vitrification and Current Clinical Applications -- Slow Freezing of Embryos -- Vitrification of Embryos -- Ovarian Tissue Cryopreservation -- Establishing and Managing Donor Oocyte Banking -- XI. Embryo Transfer and Advanced Treatment Options -- Single Embryo Transfer -- Embryo Transfer: Techniques and Trouble shooting -- G-CSF and GM-CSF: Clinical Applications in Reproductive Medicine -- The Freeze All Cycle: A New Paradigm Shift in ART -- XII. Management and Regulation in the ART Laboratory -- IVF Data Management: From Clipboards to Smart Apps -- Regulation of the ART Laboratory -- Legislation in the UK -- Regulation, Licensing, and Accreditation of the ART Laboratory in Europe -- Regulation, Licensing, and Accreditation of the ART Laboratory in Brazil -- Regulation, Licensing and Accreditation of ART Laboratories in Australia -- Trouble Shooting In Ivf Laboratories -- Benchmarking and Decision Making in the IVF Laboratory -- XIII. Innovations, Risks and Safety in ART -- Automation, Artificial Intelligence and Innovations in the Future of IVF -- Assisted Reproductive Technologies to Prevent Transmission of Mitochondrial DNA Disease -- Nuclear and Cytoplasmic Transfer: Human Applications and Concerns -- Embryo Culture and Phenotype of the Offspring -- Traceability in ART -- XIV. Molecular Reproduction -- The Role of Mitochondria in the Establishment of Developmental Competence in Early Human Development -- Cytoskeletal Architecture of Human Oocytes with a Focus on Centrosomes and Their Significant Role in Fertilization -- Molecular Mining of Follicular Fluid for Reliable Biomarkers of Human Oocyte and Embryo Developmental Competence -- Livestock Production via Micromanipulation.
- Format
- e-Book
- Location
- Online
Practical Manual of In Vitro Fertilization : Advanced Methods and Novel Devices
https://libcat.nshealth.ca/en/permalink/provcat30849
Zsolt Peter Nagy, Alex C. Varghese, Ashok Agarwal, editors.
--New York, NY:
Springer
, c2012.
- Available Online
- View e-Book
- Location
- Online
The Practical Manual of In Vitro Fertilization: Advanced Methods and Novel Devices is a unique, accessible title that provides a complete review of the most well-established and current diagnostic and treatment techniques comprising in vitro fertilization. Throughout the chapters, a uniform structure is employed, including a brief abstract, a keyword glossary, a step-by-step protocol of the laboratory procedures, several pages of expert commentary, key issues of clinical concern, and a list of …
- Available Online
- View e-Book
- Other Authors
- Nagy, Zsolt Peter
- Varghese, Alex C
- Agarwal, Ashok
- Responsibility
- Zsolt Peter Nagy, Alex C. Varghese, Ashok Agarwal, editors
- Place of Publication
- New York, NY
- Publisher
- Springer
- Date of Publication
- c2012
- Physical Description
- 1 online resource (xxiii, 703 p. : 139 ill., 103 ill. in color)
- ISBN
- 9781441917805
- Subjects (MeSH)
- Clinical Laboratory Techniques
- Fertilization in Vitro - methods
- Subjects (LCSH)
- Obstetrics
- Cytology
- Endocrinology
- Developmental biology
- Urology
- Abstract
- The Practical Manual of In Vitro Fertilization: Advanced Methods and Novel Devices is a unique, accessible title that provides a complete review of the most well-established and current diagnostic and treatment techniques comprising in vitro fertilization. Throughout the chapters, a uniform structure is employed, including a brief abstract, a keyword glossary, a step-by-step protocol of the laboratory procedures, several pages of expert commentary, key issues of clinical concern, and a list of references. The result is a readily accessible, high quality reference guide for reproductive endocrinologists, urologists, embryologists, biologists and research scientists. The Manual also offers an excellent description of novel procedures that will likely be employed in the near future. An indispensable resource for physicians and basic scientists, the Practical Manual of In Vitro Fertilization: Advanced Methods and Novel Devices is an invaluable reference and addition to the literature.
- Contents
- Journey of Human Gametes In Vitro: 1978 to 2010 -- Part I. Setting Up and Running an IVF Laboratory -- Building the Laboratory -- Air Quality Management -- Organizational Aspects of the Laboratory in a Tertiary Care ART Center -- Quality Control Management -- Daily, Weekly, and Regular Preparations for the IVF Laboratory -- Risk and Safety in the IVF Clinic -- Part II. IVF Laboratory Equipment and Culture Systems -- Essential Instruments and Disposable Supplies for an IVF Laboratory -- Co2 and Low-O2 Incubators -- IVF Workstations -- Culture Media in IVF: Decisions for the Laboratory -- Part III. In Vitro Fertilization -- Oocyte Denuding -- Assessment of Oocyte Quality -- Polarization Microscopy -- Cumulus Cell Gene Expression in Assessment of Oocyte Quality -- Part IV. Embryo Culture Methods -- Short Culture: Day 1/Day 2/Day 3 Embryo Culture -- Extended Culture in IVF -- In Vitro Maturation of Human Oocytes -- In Vivo Embryo Culture Device -- Microfluidics for Gamete Manipulation and Embryo Culture -- Part V. Sperm Processing and Selection -- Sperm Assessment: Traditional Approaches and Their Indicative Value -- Sperm Assessment: Novel Approaches and Their Indicative Value -- Sperm Processing for IVF -- PESA/TESA/TESE Sperm Processing -- Processing Sperm Samples in HIV-Positive Patients -- Intracytoplasmic Morphologically Selected Sperm Injection -- Sperm Testing and ICSI Selection by Hyaluronic Acid Binding: The Hyaluronic Acid-Coated Glass Slide and Petri Dish in the Andrology and IVF Laboratories -- Electrophoretic Sperm Separation -- Magnetic Activated Cell Sorting of Human Spermatozoa -- Poloscope-Based Sperm Selection -- Part VI. Insemination Procedures -- Intrauterine Insemination -- Conventional IVF Insemination -- Intracytoplasmic Sperm Injection -- Mechanism of Human Oocyte Activation During ICSI and Methodology for Overcoming Low or Failed Fertilization -- Part VII. Micromanipulators and Micromanipulation -- Hydraulic Manipulators for ICSI -- Research Instruments Micromanipulators -- Eppendorf Micromanipulator: Setup and Operation of Electronic Micromanipulators -- The Leica-IMSI System -- Automated Robotic Intracytoplasmic Sperm Injection -- Oocyte Treatment and Preparation for Microinjection -- Livestock Production Via Micromanipulation -- Part VIII. Embryo Evaluation, Grading, and Assisted Hatching -- Pronuclear Scoring in Human In Vitro Fertilization -- Cumulative Morphological Assessment of Embryo Quality -- Metabolomics: The ViaMetrics-E™ Procedure for Assessing Embryo Viability -- Oxygen Consumption as an Indicator of Oocyte and Embryo Viability -- Gene Expression Changes During Human Early Embryo Development: New Applications for Embryo Selection -- Amino Acid Turnover as a Biomarker of Embryo Viability -- Real-time Embryo Monitoring Devices for Embryo Selection -- Assisted Hatching in IVF -- Part IX. Biopsy Procedures on Oocytes and Embryos -- Polar Body Biopsy -- Cleavage Stage Embryo Biopsy -- Embryo Biopsy for PGD: Current Perspective -- Microarrays and CGH for PGD of Chromosome Abnormalities and Gene Defects -- Part X. Cryopreservation -- Sperm Cryopreservation -- Slow Freezing of Oocytes -- Vitrification: Research in Animal Models -- Oocyte Vitrification -- Slow Freezing of Embryos -- Vitrification of Embryos -- Directional Freezing of Reproduction Cells, Tissues, and Organs -- Ovarian Tissue Cryopreservation -- Part XI. Embryo Transfer -- Assessment of Uterine Receptivity -- Single Embryo Transfer -- Ultrasound-Guided Embryo Transfer (Abdominal/Vaginal): An Evidence-Based Evaluation -- Cumulus-Aided Embryo Transfer -- Part XII. Management and Regulation in the ART Laboratory -- Data Management in the ART Laboratory: Requirements and Solutions -- Regulation, Licensing, and Accreditation of the ART Laboratory -- Legislation in the United Kingdom -- Regulation, Licensing, and Accreditation of the ART Laboratory in Europe -- Regulation, Licensing, and Accreditation of ART Laboratories in India -- Troubleshooting in the Clinical Embryology Laboratory: The Art of Problem-Solving in ART -- Part XIII. Special Topics -- The Role of Mitochondria in the Establishment of Developmental Competence in Early Human Development -- Nuclear and Cytoplasmic Transfer: Human Applications and Concerns -- Cytoskeletal Architecture of Human Oocytes with Focus on Centrosomes and Their Significant Role in Fertilization -- Molecular Mining of Follicular Fluid for Reliable Biomarkers of Human Oocyte and Embryo Developmental Competence.
- Format
- e-Book
- Location
- Online
Preimplantation genetic diagnosis in clinical practice
https://libcat.nshealth.ca/en/permalink/provcat33680
Tarek El-Toukhy, Peter Braude, editors.
--London:
Springer
, c2014.
- Available Online
- View e-Book
- Location
- Online
This unique book offers a comprehensive yet practical user-friendly guide to preimplantation genetic diagnosis (PGD). It provides understanding of and insight into the complete procedure, its recent clinical and laboratory developments and its future prospects, whilst offering an easy point of reference for patient enquiries. Concluding with perspectives on the ethical and social issues often encountered by healthcare professionals counselling patients with regards to PGD. Each chapter within P…
- Available Online
- View e-Book
- Other Authors
- El-Toukhy, Tarek
- Braude, Peter R
- Responsibility
- Tarek El-Toukhy, Peter Braude, editors
- Place of Publication
- London
- Publisher
- Springer
- Date of Publication
- c2014
- Physical Description
- 1 online resource (xvii, 228 pages)
- ISBN
- 9781447129486 (electronic bk.)
- 9781447129479
- Subjects (MeSH)
- Genetic testing
- Preimplantation Diagnosis
- Subjects (LCSH)
- Preimplantation genetic diagnosis
- Genetic Counseling
- Preimplantation Diagnosis
- Obstetrics
- Reproductive medicine
- Obstetrics/Perinatology
- Maternal and Child Health
- Practice Management
- Abstract
- This unique book offers a comprehensive yet practical user-friendly guide to preimplantation genetic diagnosis (PGD). It provides understanding of and insight into the complete procedure, its recent clinical and laboratory developments and its future prospects, whilst offering an easy point of reference for patient enquiries. Concluding with perspectives on the ethical and social issues often encountered by healthcare professionals counselling patients with regards to PGD. Each chapter within Preimplantation Genetic Diagnosis in Clinical Practice is written by established authorities in their fields. An essential resource for PGD specialists and non-specialists, and for all practitioners working within the disciplines of fertility, reproductive medicine and medical genetics.
- Contents
- Introduction -- Basic genetics for PGD -- Genetic counselling and its role in PGD -- Complex issues in PGD -- Assisted reproductive care for PGD patients -- Embryology and PGD -- PGD for sex-determination and chromosome rearrangements: FISH and emerging technologies -- PGD analysis of embryos for monogenic disorders -- Managing the PGD cycle -- Training and accreditation in PGD -- PGD data in the UK and Europe -- PGD facts and figures -- Pre-implantation diagnosis and HLA-typing: the potential for selection of unaffected HLA matched siblings -- PGD and human embryonic stem cell technology -- Ethical and social aspects of PGD -- Preimplantation genetic screening -- Regulation of PGD in the UK and worldwide -- New developments in PGD -- The future of preimplantation genetic testing: from research lab to responsible patient care.
- Format
- e-Book
- Location
- Online
Prenatal and Preimplantation Diagnosis : The Burden of Choice
https://libcat.nshealth.ca/en/permalink/provcat39328
Joann Paley Galst, Marion S. Verp, editors.
--Cham:
Springer
, c2015.
- Available Online
- View e-Book
- Location
- Online
This book aims to expand the awareness and understanding of the emotional sequelae of prenatal/preimplantation diagnosis, prenatal decision-making, pregnancy interruption for fetal anomaly, multifetal reduction for high-order multifetal pregnancies, and preimplantation choices involving the selection of embryos. Featuring a multi-disciplinary approach, it examines prenatal and preimplantation diagnosis from medical, legal, ethical, and psychosocial perspectives. Prenatal and Preimplantation Dia…
- Available Online
- View e-Book
- Other Authors
- Paley Galst, Joann
- Verp, Marion S
- Responsibility
- Joann Paley Galst, Marion S. Verp, editors
- Place of Publication
- Cham
- Publisher
- Springer
- Date of Publication
- c2015
- Physical Description
- 1 online resource (xvi, 354 p. : 20 illus., 14 illus. in color)
- ISBN
- 9783319189116
- 9783319189109 (print ed.)
- Subjects (MeSH)
- Bioethical Issues
- Genetic testing
- Preimplantation Diagnosis
- Prenatal Diagnosis - ethics
- Abstract
- This book aims to expand the awareness and understanding of the emotional sequelae of prenatal/preimplantation diagnosis, prenatal decision-making, pregnancy interruption for fetal anomaly, multifetal reduction for high-order multifetal pregnancies, and preimplantation choices involving the selection of embryos. Featuring a multi-disciplinary approach, it examines prenatal and preimplantation diagnosis from medical, legal, ethical, and psychosocial perspectives. Prenatal and Preimplantation Diagnosis is an excellent resource for obstetricians, reproductive endocrinologists, clinical geneticists, genetic counselors, and mental health professionals seeking to better support patients faced with difficult choices.
- Contents
- Part I. Medical Perspective -- Prenatal Screening and Diagnostic Testing -- Preimplantation Genetic Screening and Diagnostic Testing -- Medical Reasons for Pregnancy Interruption: Chromosomal and Genetic Abnormalities -- Medical Reasons for Pregnancy Interruption: Structural Abnormalities -- Medical Reasons or Pregnancy Interruption: Fetal Reduction -- Fetal Pain -- Giving Bad and Ambiguous News -- Part II. The Legal Landscape -- Legal Issues in Prenatal and Preimplantation Genetic Diagnosis -- Part III. Alternative Social Perspectives -- Ethical Issues -- Religious Traditions -- Disability Perspectives -- Feminist Perspectives on Prenatal and Preimplantation Diagnosis -- Part IV. Psychosocial Perspective -- Critical Aspects of Decision-Making and Grieving After Diagnosis of Fetal Anomaly -- Helping Patients Cope with Their Decisions -- A Burden of Choice: The Ripple Effect: Parents' Grief and the Role of Family and Friends -- Postscript: A Patient's Perspective.
- Format
- e-Book
- Location
- Online
Preventing Age Related Fertility Loss
https://libcat.nshealth.ca/en/permalink/provcat43382
Dominic Stoop, editor.
--Cham:
Springer
, c2018.
- Available Online
- View e-Book
- Location
- Online
This unique book provides expert advice on all the different aspects related to fertility preservation for age related infertility. Although, there is a lot of information about fertility preservation for cancer treatment available, there is little information for young women. While men have been able to cryopreserve sperm since the 1950s, women have only recently gained the opportunity to preserve their gametes through the egg vitrification technique. Therefore, many women confronted with a ri…
- Available Online
- View e-Book
- Other Authors
- Stoop, Dominic
- Responsibility
- Dominic Stoop, editor
- Place of Publication
- Cham
- Publisher
- Springer
- Date of Publication
- c2018
- Physical Description
- 1 online resource (viii, 172 p.) : 21 illus., 15 illus. in color
- ISBN
- 9783319148571
- 9783319148564 (print ed.)
- 9783319148588 (print ed.)
- 9783319792057 (print ed.)
- Subjects (MeSH)
- Age Factors
- Cryopreservation - methods
- Infertility, Female - etiology
- Infertility, Female - prevention & control
- Oocytes
- Reproductive Health
- Specialty
- Reproductive Medicine
- Abstract
- This unique book provides expert advice on all the different aspects related to fertility preservation for age related infertility. Although, there is a lot of information about fertility preservation for cancer treatment available, there is little information for young women. While men have been able to cryopreserve sperm since the 1950s, women have only recently gained the opportunity to preserve their gametes through the egg vitrification technique. Therefore, many women confronted with a risk of imminent fertility loss, such as chemotherapy, are now freezing their oocytes instead of embryos. Successful oocyte cryopreservation offers them a reproductive autonomy independent of men.
- Contents
- 1. Female Age and Reproductive Chances -- 2. Late Motherhood in Low-Fertility Countries: Reproductive Intentions, Trends and Consequences -- 3. Treatment Options for Age Related Fertility Loss -- 4. Preliminary Assessment Prior to Oocyte Cryopreservation -- 5. Alternative Options for Preventive Oocyte Cryopreservation -- 6. The Profile of a Pioneer Cohort of Women Opting for Oocyte Cryopreservation for Non-medical Reasons -- 7. Ovarian Stimulation Prior to Elective Oocyte Cryopreservation -- 8. Oocyte Cryopreservation Technique -- 9. Optimal Preparation Prior to the Use of Cryopreserved Oocytes -- 10. Clinical Outcome After Oocyte Cryopreservation for Elective Fertility Preservation -- 11. Safety of Preventive Oocyte Cryopreservation -- 12. Procreative Procrastination: The Ethics of Postponed Parenthood -- 13. Ethical Aspects of AGE Banking.
- Format
- e-Book
- Location
- Online
Principles of Oocyte and Embryo Donation
https://libcat.nshealth.ca/en/permalink/provcat32545
Mark V. Sauer, editor.
(2nd ed.)
--London:
Springer
, c2013.
- Available Online
- View e-Book
- Location
- Online
The versatility of oocyte and embryo donation has proven to be extremely valuable to both patients and doctors engaged in reproductive medicine. Originally thought to be applicable only to a rather small subset of infertile women, today busy practices commonly recommend the procedure and it is estimated that nearly all of the 400 or more IVF programs in the United States provide these services. Oocyte and embryo donation has established itself as a mainstay procedure within assisted reproductiv…
- Available Online
- View e-Book
- Other Authors
- Sauer, Mark V
- Responsibility
- Mark V. Sauer, editor
- Edition
- 2nd ed.
- Place of Publication
- London
- Publisher
- Springer
- Date of Publication
- c2013
- Physical Description
- 1 online resource (xxi, 426 p. : 43 ill., 35 ill. in color)
- ISBN
- 9781447123927
- Subjects (MeSH)
- Embryo Transfer
- Oocyte Donation
- Subjects (LCSH)
- Gynecology
- Obstetrics
- Reproductive medicine
- Abstract
- The versatility of oocyte and embryo donation has proven to be extremely valuable to both patients and doctors engaged in reproductive medicine. Originally thought to be applicable only to a rather small subset of infertile women, today busy practices commonly recommend the procedure and it is estimated that nearly all of the 400 or more IVF programs in the United States provide these services. Oocyte and embryo donation has established itself as a mainstay procedure within assisted reproductive care, and the breadth, depth and complexity of practice is deserving of focused attention. Much has changed within the field of oocyte and embryo donation since the publication of the first edition of Principles of Oocyte and Embryo Donation in 1998, thus the need for a completely updated and more expansive text. The second edition of this book provides an overview of the major issues affecting men and women engaged in the practice of oocyte and embryo donation. A primary emphasis has been placed on defining the standards of practice that have evolved over the past 30 years, clearly stating the outcomes expected from adhering to these established protocols. Details of both the basic science and the clinical medicine are presented together and attention is also focused on the non-reproductive aspects inherent to this unique method of assisted reproduction that involves opinions from lawyers, ethicists, mental health care professionals and theologians. Oocyte and embryo donation requires a working knowledge of the medicine, the law and the ethics that underlies its foundation. This book is intended to serve as a complete and comprehensive reference for all health care professionals that provide services related to egg donation, reproductive endocrinologists, obstetrician- gynecologists, and fellows and residents entering the fertility field.
- Contents
- Part I. PRELIMINARY CONSIDERATIONS FOR PATIENTS AND CLINICIANS -- History of the Technique and its Importance to Understanding Modern Methodology -- Indications for Egg and Embryo Donation -- Success and Anticipated Pregnancy Outcomes for Oocyte and Embryo Donation -- Selecting and Screening Donors -- Selecting and Screening Recipients: Diminished Ovarian Reserve and Premature Ovarian Failure -- Selecting and Screening Recipients: Advanced Reproductive Age -- Genetic Aspects of Donor Selection -- Part II. PRACTICAL ASPECTS OF CLINICAL CARE -- Sychronization of Donors and Recipients: Practical Aspects of Clinical Surveillance -- Preparing the Endometrium to Maximize Success: The Dynamic of Artificial Cycles -- Blastocyst versus Cleavage Stage Embryo Transfer: Maximizing Success Rates -- Strategies to Minimize Multiple Births in Recipients of Egg Donation -- What is the Outcome and Fate of Frozen Supernumerary Embryos Resulting from Egg Donation? -- Prenatal Considerations after Oocyte Donation -- Defining, Understanding and Managing the Complex Psychological Aspects of Third Party Reproduction -- Disclosure Decisions Among Known and Anonymous Egg Donor Recipients -- Risk and Complications Associated with Egg Donation -- Part III. OFFICE PRACTICE MANAGEMENT -- The Role of the Donor Oocyte Nurse Coordinator -- The Finances of Egg Donation -- Donor/Recipient Insurance Coverage: Protecting Against Unexpected Liability -- Part IV. NEW FRONTIERS IN EGG AND EMBRYO DONATION -- Egg and Embryo Banking: Essential Elements for Maintaining High Rates of Success -- Gestational Carriers and Surrogacy -- Assisted Reproduction in Same Sex Couples -- Immunologic and Clinical Consequences of Oocyte Donation Pregnancies -- Part V. LEGAL AND REGULATORY ISSUES -- FDA Regulatory Approach to Reproductive Tissues -- Essential Elements of Informed Consent in Egg Donation and Surrogacy -- Statutory and Case Law Governing the Practice of Third Party Reproduction -- Part VI. CULTURE, RELIGION AND ETHICS -- Health Equity and Access to Oocyte Donation -- Religious Views: The Impact of Traditional Theological Opinion on the Practice of Third-Party Reproduction -- Ethics of Egg and Embryo Donation -- Ethical Issues: Addressing the Sensational Cases and Analyzing the Clinical Practice.
- Format
- e-Book
- Location
- Online
Radiation protection in nuclear medicine
https://libcat.nshealth.ca/en/permalink/provcat32507
Sören Mattsson, Christoph Hoeschen, editors.
--Berlin, Heidelberg:
Springer
, c2013.
- Available Online
- View e-Book
- Location
- Online
This book explains clearly and in detail all aspects of radiation protection in nuclear medicine. After an introductory chapter on the general role of radiation protection, measurement quantities and units are discussed, and detectors and dosimeters, described. Radiation biology and radiation dosimetry are then addressed, with the inclusion of a chapter specifically devoted to biology and dosimetry for the lens of the eye. Discussion of radiation doses to patients and to embryos, fetuses, and c…
- Available Online
- View e-Book
- Other Authors
- Mattsson, Sören
- Hoeschen, Christoph
- Responsibility
- Sören Mattsson, Christoph Hoeschen, editors
- Place of Publication
- Berlin, Heidelberg
- Publisher
- Springer
- Date of Publication
- c2013
- Physical Description
- 1 online resource (viii, 159 p. : 39 ill., 32 ill. in color)
- ISBN
- 9783642311673
- Subjects (MeSH)
- Radiation Dosage
- Radiation Injuries - prevention & control
- Radiation Protection - methods
- Radionuclide Imaging - adverse effects
- Subjects (LCSH)
- Nuclear medicine
- Abstract
- This book explains clearly and in detail all aspects of radiation protection in nuclear medicine. After an introductory chapter on the general role of radiation protection, measurement quantities and units are discussed, and detectors and dosimeters, described. Radiation biology and radiation dosimetry are then addressed, with the inclusion of a chapter specifically devoted to biology and dosimetry for the lens of the eye. Discussion of radiation doses to patients and to embryos, fetuses, and children forms a central part of the book. Phantom models, biokinetic models, calculations, and software solutions are all considered, and a further chapter focuses on quality assurance and reference levels. Occupational exposure also receives detailed attention. Exposure resulting from the production, labeling, and injection of radiopharmaceuticals and from contact with patients is discussed and shielding calculations are explained. The book closes by considering exposure of the public and summarizing the "rules of thumb" for radiation protection in nuclear medicine. This is an ideal textbook for students and a ready source of useful information for nuclear medicine specialists and medical physics experts.
- Contents
- Introduction -- Part I. Measurements -- Part II. Radiation Biology -- Part III. Radiation Dose Estimations -- Part IV. Quality Assurance and Quality Control -- Part V. Occupational Exposure -- Part VI. Exposure of the Public -- Part VII. Rules of Thumb for Radiation Protection in Nuclear Medicine -- Index.
- Format
- e-Book
- Location
- Online
Recurrent Implantation Failure : Etiologies and Clinical Management
https://libcat.nshealth.ca/en/permalink/provcat42599
Jason M. Franasiak, Richard T. Scott Jr., editors.
--Cham:
Springer
, c2018.
- Available Online
- View e-Book
- Location
- Online
This unique text discusses the wide range of causes and pathophysiologic conditions contributing to recurrent implantation failure (RIF) and the current treatment approaches to best approach this challenging patient population. Beginning with a presentation of the mechanism of normal implantation, the physiologic synchrony between embryo and endometrium, and the roles of both gametes and embryos in RIF, the book then examines the various genetic, immune and environmental factors involved. Abnor…
- Available Online
- View e-Book
- Other Authors
- Franasiak, Jason M.
- Scott Jr., Richard T.
- Responsibility
- Jason M. Franasiak, Richard T. Scott Jr., editors
- Place of Publication
- Cham
- Publisher
- Springer
- Date of Publication
- c2018
- Physical Description
- 1 online resource (xiii, 215 p.) : 32 illus., 29 illus. in color
- ISBN
- 9783319719672
- 9783319719665 (print ed.)
- 9783319719689 (print ed.)
- Subjects (MeSH)
- Embryo Implantation - physiology
- Embryo Transfer - adverse effects
- Infertility, Female - etiology
- Reproductive Techniques, Assisted - adverse effects
- Treatment Failure
- Treatment Outcome
- Specialty
- Obstetrics
- Reproductive Medicine
- Abstract
- This unique text discusses the wide range of causes and pathophysiologic conditions contributing to recurrent implantation failure (RIF) and the current treatment approaches to best approach this challenging patient population. Beginning with a presentation of the mechanism of normal implantation, the physiologic synchrony between embryo and endometrium, and the roles of both gametes and embryos in RIF, the book then examines the various genetic, immune and environmental factors involved. Abnormalities of the hematologic and endocrine system, as well as those of the anatomy and microbiome, are described in detail. Last but no less important, the psychological stress and treatment of patients experiencing RIF is discussed. Assisted reproductive technology (ART) success has increased substantially over the past three decades. However, despite these advances, recurrent implantation failure is still a common issue confronting patients and clinicians, and RIF represents one of the greatest challenges in ART and remains a source of frustration and disappointment for patients, clinicians, and researchers involved in the process. Providing an in-depth investigation into the pathophysiology and biological mechanisms of RIF and its clinical management, this will be an excellent resource for reproductive endocrinologists and infertility specialists.
- Contents
- Signaling Between Embryo and Endometrium: Normal Implantation -- Embryo and Endometrial Synchrony in Implantation Failure -- Spermatogenesis: Fertile Ground for Contributing to Recurrent Implantation Failure? -- Embryonic Factors Associated with Recurrent Implantation Failure -- The Genetics of Pregnancy Failure -- Immune Factors in Recurrent Implantation Failure -- Stress and Recurrent Implantation Failure -- Hematologic Disease in Recurrent Implantation Failure -- Endocrine Causes of Recurrent Implantation Failure -- Anatomic Abnormalities and Recurrent Implantation Failure -- Microbiome in Embryonic Implantation and Recurrent Implantation Failure -- Psychosocial Implications of Recurrent Implantation Failure.
- Format
- e-Book
- Location
- Online
Treatment Strategy for Unexplained Infertility and Recurrent Miscarriage
https://libcat.nshealth.ca/en/permalink/provcat43098
Keiji Kuroda, Jan J. Brosens, Siobhan Quenby, Satoru Takeda, editors.
--Singapore:
Springer
, c2018.
- Available Online
- View e-Book
- Location
- Online
This book offers a highly informative guide to treating unexplained infertility and recurrent miscarriage (RM). In particular, it provides detailed treatment strategies for infertility or RM derived from uterine circumstance such as chronic endometritis and perturbation of endometrial decidualization, as well as maternal immunological rejection of an embryo as semi-allograft. Unexplained infertility refers to those types that cannot be detected by the general screening test. The causes are some…
- Available Online
- View e-Book
- Other Authors
- Kuroda, Keiji
- Brosens, Jan J.
- Quenby, Siobhan
- Takeda, Satoru
- Responsibility
- Keiji Kuroda, Jan J. Brosens, Siobhan Quenby, Satoru Takeda, editors
- Place of Publication
- Singapore
- Publisher
- Springer
- Date of Publication
- c2018
- Physical Description
- 1 online resource (viii, 125 p.) : 39 illus., 30 illus. in color
- ISBN
- 9789811086908
- 9789811086892 (print ed.)
- 9789811086915 (print ed.)
- 9789811342158 (print ed.)
- Subjects (MeSH)
- Infertility, Female - etiology
- Infertility, Female - therapy
- Abortion, Habitual - therapy
- Reproductive Techniques, Assisted
- Specialty
- Reproductive Medicine
- Abstract
- This book offers a highly informative guide to treating unexplained infertility and recurrent miscarriage (RM). In particular, it provides detailed treatment strategies for infertility or RM derived from uterine circumstance such as chronic endometritis and perturbation of endometrial decidualization, as well as maternal immunological rejection of an embryo as semi-allograft. Unexplained infertility refers to those types that cannot be detected by the general screening test. The causes are sometimes detected in the course of treatment with assisted reproductive technology including IVF. However, some unexplained infertility is intractable even after intracytoplasmic sperm injection or repeated implantation of morphologically suitable embryos. Patients with unexplained RM also have a high likelihood of undetectable risk factors of miscarriage. As a result, gynecologists often repeatedly provide these couples with general treatments for infertility and miscarriage or even discontinue treatment because they cannot detect the reason, which places serious financial, physical and mental burdens on the couples affected. This book offers gynecologists essential insights into the pathological condition of unexplained infertility and RM, equipping them to identify it, explain it to patients, and consider further examinations and more aggressive fertility treatments.
- Contents
- Part I. Unexplained Infertility -- 1. Unexplained Infertility: Introduction -- 2. Fertilization Failure -- 3. Tubal Function Abnormalities with Tubal Patency in Unexplained Infertility -- 4. Implantation Failure 1: Intrauterine Circumstances and Embryo-Endometrium Synchrony at Implantation -- 5. Implantation Failure 2: Immunomodulating Treatment for the Patients with Repeated Implantation Failures Caused by Immunological Rejection -- 6. Unexplained Infertility: Treatment Strategy for Unexplained Infertility -- Part II. Unexplained Recurrent Miscarriage -- 7. Unexplained Recurrent Miscarriage: Introduction -- 8. Previous Trial Studies of Unexplained Recurrent Miscarriage -- 9. Lifestyle Habits and Pregnancy Loss -- 10. Perturbation of Endometrial Decidualization -- 11. Treatment Strategy for Unexplained Recurrent Miscarriage.
- Format
- e-Book
- Location
- Online
