Antiangiogenic Agents in Cancer Therapy
https://libcat.nshealth.ca/en/permalink/provcat40632
edited by Beverly A. Teicher, Lee M. Ellis.
(2nd ed.)
--Totowa, NJ:
Humana Press
, c2008.
- Available Online
- View e-Book
- Location
- Online
Antiangiogenesis remains a dynamic and evolving field in oncology. New therapeutic targets continue to emerge followed by the rapid development of new therapeutic agents to be investigated in clinical trials. Optimizing the therapeutic potential of antiangiogenic agents in combination with the other therapies in the armamentarium to fight cancer will be an on-going challenge. Antiangiogenic Agents in Cancer Therapy, Second Edition provides a current, up-dated perspective on the state of the art…
- Available Online
- View e-Book
- Other Authors
- Teicher, Beverly A
- Ellis, Lee M
- Responsibility
- edited by Beverly A. Teicher, Lee M. Ellis
- Edition
- 2nd ed.
- Place of Publication
- Totowa, NJ
- Publisher
- Humana Press
- Date of Publication
- c2008
- Physical Description
- 1 online resource (xviii, 559 p. : ill.)
- Series Title
- Cancer drug discovery and development
- ISBN
- 9781597451840
- 9781588298706 (print ed.)
- Subjects (MeSH)
- Angiogenesis Inhibitors - therapeutic use
- Antineoplastic Agents - therapeutic use
- Neoplasms - drug therapy
- Neovascularization, pathologic - drug therapy
- Abstract
- Antiangiogenesis remains a dynamic and evolving field in oncology. New therapeutic targets continue to emerge followed by the rapid development of new therapeutic agents to be investigated in clinical trials. Optimizing the therapeutic potential of antiangiogenic agents in combination with the other therapies in the armamentarium to fight cancer will be an on-going challenge. Antiangiogenic Agents in Cancer Therapy, Second Edition provides a current, up-dated perspective on the state of the art of angiogenesis and therapy with a compendium of scientific findings and approaches to the study of angiogenesis in cancer. Leaders in the field present chapters on such topics as the environmental influences and the genetic and physiologic abnormalities that mediate angiogenesis and its role in the progression of malignant disease, working models of tumor angiogenesis, and the role of angiogenesis inhibition in the therapy of malignant disease in humans. Comprehensive and cutting-edge, Antiangiogenic Agents in Cancer Therapy, Second Edition is an ideal, valuable guide to the most recent advances in the field, and a collection that will be useful for many years to come.
- Contents
- Part I. Basic Biology of Angiogenesis -- Vascular Endothelial Growth Factor Family and Its Receptors -- The Cycle Between Angiogenesis, Perfusion, and Hypoxia in Tumors -- The Role of Integrins in Tumor Angiogenesis -- Tumor Endothelial Cell Abnormalities -- The Extracellular Matrix and VEGF Processing -- Endothelial Precursor Cells -- Role of Pericytes in Angiogenesis -- Newer Vascular Targets -- Chemokines in Angiogenesis -- Angiopoietin/Tie2 Signaling Regulates Tumor Angiogenesis -- Imaging Angiogenesis -- Tumor Blood Vessels -- Lymphatic System in the Pathology of Cancer -- Part II. Translational Research in Tumor Angiogenesis -- VEGF in the Adult -- Normalization of Tumor Vasculature and Microenvironment -- Metronomic Low-Dose Antiangiogenic Chemotherapy in Mice and Man -- Small-Molecule Vascular Disrupting Agents in Cancer Therapy -- Normalization of Tumor Vasculature and Improvement of Radiation Response by Antiangiogenic Agents -- Challenges in Translating Antiangiogenic Therapy from the Bench to Bedside -- Regulation of Angiogenesis in Cancer and Its Therapeutic Implications -- Part III. Antiangiogenic Therapy in the Clinical Trial Results and Future Directions -- Angiogenesis and Angiogenesis Inhibition in Sarcomas -- Antiangiogenesis Agents in Colorectal Cancer -- Antiangiogenic Therapy for Primary CNS Tumors -- Angiogenesis Inhibitors for the Treatment of Lung Cancer -- Antiangiogenic Therapy of Renal Cell Carcinoma -- Antiangiogenesis Therapies in Gynecologic Malignancies -- Antiangiogenic Agents in Myeloid Malignancies -- Angiogenesis in Malignant and Non-Malignant Pediatric Tumors -- Prognostic and Predictive Significance of Surrogate Biomarkers of Angiogenesis -- Endpoints for the Determination of Efficacy of Antiangiogenic Agents in Clinical Trials -- The Role of Imaging in the Clinical Development of Antiangiogenic Agents.
- Format
- e-Book
- Location
- Online
Asthma : Targeted Biological Therapies
https://libcat.nshealth.ca/en/permalink/provcat41552
Girolamo Pelaia, Alessandro Vatrella, Rosario Maselli.
--Cham:
Springer
, 2017.
- Available Online
- View e-Book
- Location
- Online
This book focuses on the fundamentals of the use of biologics in asthma, describing the rationale, principles, mechanisms of action, and indications. It offers an excellent balance between basic science and the analysis of clinical trials, updating readers with new developments that are changing the global scenario for targeted biological anti-asthma therapies, especially with regard to more severe disease. A range of therapies are considered, from the humanized monoclonal anti-IgE antibody oma…
- Available Online
- View e-Book
- Author
- Pelaia, Girolamo
- Other Authors
- Vatrella, Alessandro
- Maselli, Rosario
- Responsibility
- Girolamo Pelaia, Alessandro Vatrella, Rosario Maselli
- Place of Publication
- Cham
- Publisher
- Springer
- Date of Publication
- 2017
- Physical Description
- 1 online resource (vi, 99 pages) : 11 illus. in color
- ISBN
- 9783319460079
- 9783319460055 (print ed.)
- Subjects (MeSH)
- Asthma - drug therapy
- Biological Therapy
- Precision Medicine
- Abstract
- This book focuses on the fundamentals of the use of biologics in asthma, describing the rationale, principles, mechanisms of action, and indications. It offers an excellent balance between basic science and the analysis of clinical trials, updating readers with new developments that are changing the global scenario for targeted biological anti-asthma therapies, especially with regard to more severe disease. A range of therapies are considered, from the humanized monoclonal anti-IgE antibody omalizumab, widely approved as add-on treatment for inadequately controlled disease, through to emerging biologics for which evidence supportive of efficacy is accumulating, including anti-IL-5, anti-IL-4, and anti-IL-13 therapies. One aspect to emerge is the variability in individual response, which suggests a need for characterization of different asthma subtypes to permit the effective implementation of phenotype-targeted treatments. This book will be of interest for pulmonologists, clinical immunologists, and physicians seeking sound information on these therapies, but also for scientists and pharmacologists wishing to enhance their knowledge of the therapeutic implications of the cellular and molecular mechanisms that underlie severe, uncontrolled asthma.
- Contents
- 1. Introduction -- 2. Inflammatory Cellular Patterns in Asthma -- 3. Airway Remodelling in Asthma -- 4. Anti-IgE Therapy -- 5. IL-5-Targeted Antibodies -- 6. Anti-IL-4/IL-13 Biologics -- 7. Anti-TNF-a Therapies -- 8. Biologic Treatments Targeted to Innate Cytokines -- 9. Other Biologic Drugs -- 10. Conclusions and Future Perspectives.
- Format
- e-Book
- Location
- Online
Bariatric Psychology and Psychiatry
https://libcat.nshealth.ca/en/permalink/provcat45257
Alfonso Troisi.
--Cham:
Springer
, c2020.
- Available Online
- View e-Book
- Location
- Online
This book offers a step-by-step guide to mental health assessment for bariatric surgery patients. A general introduction explains the concepts of bariatric psychology and psychiatry, their relevance in contemporary bariatric surgery, and reasons to include psychologists and psychiatrists in multidisciplinary teams taking care of bariatric patients. The following four chapters address the aspects of mental health that are investigated by bariatric psychology. The psychological processes analyzed…
- Available Online
- View e-Book
- Author
- Troisi, Alfonso
- Responsibility
- Alfonso Troisi
- Place of Publication
- Cham
- Publisher
- Springer
- Date of Publication
- c2020
- Physical Description
- 1 online resource (xvi, 150 p.) : 6 illus., 5 illus. in color
- ISBN
- 9783030448349
- 9783030448332 (Print ed.)
- 9783030448356 (Print ed.)
- 9783030448363 (Print ed.)
- Subjects (MeSH)
- Bariatrics - psychology
- Obesity - psychology
- Specialty
- Bariatric Medicine
- Abstract
- This book offers a step-by-step guide to mental health assessment for bariatric surgery patients. A general introduction explains the concepts of bariatric psychology and psychiatry, their relevance in contemporary bariatric surgery, and reasons to include psychologists and psychiatrists in multidisciplinary teams taking care of bariatric patients. The following four chapters address the aspects of mental health that are investigated by bariatric psychology. The psychological processes analyzed here play a major role in influencing patients’ perception of the outcomes of bariatric surgery and in determining their commitment to lifestyle changes and follow-up programs. The second part of the book includes nine chapters addressing the clinical conditions relevant to bariatric psychiatry. For each condition, the major focus is on the impact of psychopathology on bariatric surgery outcomes (weight loss, weight regain, quality of life) and the impact of surgery on its course (remission, worsening, de novo onset). Each chapter in this part includes a discussion of the diagnostic instruments (i.e., structured interviews, clinician-rated tests, and patient-rated tests) that should be used to obtain a valid assessment of the patient’s mental status. Separate chapters focus on psychiatric complications (e.g., suicide and addiction transfer) and psychological problems related to quality of life (e.g., body image dissatisfaction) that may emerge postoperatively. Data on these postsurgery conditions has been reported only recently and, therefore, no published book deals with them. The final chapter offers an overview of unsolved issues in bariatric psychology and psychiatry and reviews emerging research findings that are likely to change assessment and care of bariatric patients’ mental health in the near future. Given its scope—and its wealth of tables, diagrams, mnemonics, and key fact boxes—the book will be an invaluable reference tool for clinicians.
- Contents
- Bariatric surgery and mental health -- Patients’ motivations, expectations, and experiences -- Personality traits -- Body image and body dissatisfaction -- Childhood trauma -- Eating disorders -- Depressive disorders -- Anxiety disorders, OCD, and PTSD -- Personality disorders -- Bipolar disorder -- Psychotic disorders -- Intellectual disability -- Substance and alcohol use disorders -- Suicide and self-harm -- Current problems and future directions -- Appendix: Assessment toolbox.
- Format
- e-Book
- Location
- Online
Biomarkers in Periodontal Health and Disease : Rationale, Benefits, and Future Directions
https://libcat.nshealth.ca/en/permalink/provcat44899
Nurcan Buduneli.
--Cham:
Springer
, c2020.
- Available Online
- View e-Book
- Location
- Online
This book examines all aspects of the progress being made towards the development of highly specific and sensitive biomarkers that will overcome the shortcomings of clinical assessments in periodontics. The opening chapters present the basic anatomic features of periodontal tissues, outline the nature and pathogenic mechanisms of periodontal diseases, and discuss both conventional and novel methods of diagnosis with reference to their specificity and sensitivity. The potential role of biomarker…
- Available Online
- View e-Book
- Author
- Buduneli, Nurcan
- Responsibility
- Nurcan Buduneli
- Place of Publication
- Cham
- Publisher
- Springer
- Date of Publication
- c2020
- Physical Description
- 1 online resource (xv, 90 p.) : 34 illus., 33 illus. in color
- ISBN
- 9783030373177
- 9783030373153 (Print ed.)
- 9783030373160 (Print ed.)
- Subjects (MeSH)
- Biomarkers
- Periodontal Diseases - diagnosis
- Specialty
- Dentistry
- Diagnosis
- Oral Health
- Abstract
- This book examines all aspects of the progress being made towards the development of highly specific and sensitive biomarkers that will overcome the shortcomings of clinical assessments in periodontics. The opening chapters present the basic anatomic features of periodontal tissues, outline the nature and pathogenic mechanisms of periodontal diseases, and discuss both conventional and novel methods of diagnosis with reference to their specificity and sensitivity. The potential role of biomarkers in periodontal diagnosis is then presented in the light of the published data. The biological samples in which potential biomarkers are sought are evaluated comparatively, drawing attention to their strengths and weaknesses, and the available technologies for biomarker studies are reviewed. The potential benefits of biomarkers are also discussed with regard to the possible bidirectional interactions between periodontal diseases and systemic health. Finally, the past, present, and future of periodontics are examined from a broader perspective. Readers will find the book to be an ideal summary of the state of the art in the field as biomarkers emerge that promise to facilitate periodontal diagnostics and permit timely, personally tailored interventions.
- Contents
- 1. Anatomy of Periodontal Tissues -- 2. Nature of Periodontal Diseases -- 3. Conventional Diagnosis of Periodontal Diseases and 2017 Classification System -- 4. Novel Diagnostic Approaches in Periodontics -- 5. Biomarkers for Periodontal Diseases -- 6. Biological Samples for Biomarkers: Strengths and Weaknesses -- 7. Technologies for Biomarkers in Periodontics -- 8. Biomarkers in Periodontal Disease and Systemic Health Intersection -- 9. Past, Present and Future of Periodontics.
- Format
- e-Book
- Location
- Online
A Clinical Guide to Occupational and Environmental Lung Diseases
https://libcat.nshealth.ca/en/permalink/provcat31031
Yuh-Chin T. Huang, Andrew J. Ghio, Lisa A. Maier, editors.
--New York, NY:
Humana Press
, c2012.
- Available Online
- View e-Book
- Location
- Online
A Clinical Guide to Occupational and Environmental Lung Diseases delivers a concise compendium to the diagnosis and management of occupational and environmental lung diseases, incorporating evidence-based guidelines where available. Each chapter provides an updated review and a practical approach to different occupational and environmental lung diseases. With rapidly changing technology, new conditions and exposures will undoubtedly emerge. Clinicians need to remain vigilant about assessing the…
- Available Online
- View e-Book
- Other Authors
- Huang, Yuh-Chin T
- Ghio, Andrew J
- Maier, Lisa A
- Responsibility
- Yuh-Chin T. Huang, Andrew J. Ghio, Lisa A. Maier, editors
- Place of Publication
- New York, NY
- Publisher
- Humana Press
- Date of Publication
- c2012
- Physical Description
- 1 online resource (xiii, 323 p. : 49 ill., 13 ill. in color)
- Series Title
- Respiratory medicine (New York, N.Y.)
- ISBN
- 9781627031493
- Subjects (MeSH)
- Environmental Illness
- Lung Diseases
- Occupational Diseases
- Subjects (LCSH)
- Pneumology
- Environmental medicine
- Abstract
- A Clinical Guide to Occupational and Environmental Lung Diseases delivers a concise compendium to the diagnosis and management of occupational and environmental lung diseases, incorporating evidence-based guidelines where available. Each chapter provides an updated review and a practical approach to different occupational and environmental lung diseases. With rapidly changing technology, new conditions and exposures will undoubtedly emerge. Clinicians need to remain vigilant about assessing the potential link between lung diseases and environmental exposures, and this book provides a practical guide to recognize, diagnose, and prevent occupational and environmental lung diseases. Written for practicing clinicians including internists, pulmonologists, and primary care providers, as well as industrial hygienists and environmental regulators, A Clinical Guide to Occupational and Environmental Lung Diseases is a timely and important new volume and an invaluable contribution to the literature.
- Contents
- Historical Perspective of Occupational and Environmental Lung Disease -- The Occupational and Environmental History -- Use of Laboratory Tests in Occupational and Environmental Lung Diseases -- Radiography and CT of Occupational and Environmental Lung Diseases -- Environmental and Occupational Causes of Asthma -- Hypersensitivity Pneumonitis -- Air Pollution and Lung Diseases -- Unanswered questions regarding asbestos exposure: Concerns for the Next Generation -- Pneumoconiosis in the 21st century -- Inhalation Injury -- Hard Metal Lung Disease -- Beryllium Disease -- Occupational Lung Cancer -- COPD in non-smokers -- Emerging Issues in Environmental and Occupational Lung Diseases -- Disability Assessment in Occupational and Environmental Lung Diseases -- Global Impact of Occupational and Environmental Lung Diseases.
- Format
- e-Book
- Location
- Online
The Common Sense Guide to Dementia For Clinicians and Caregivers
https://libcat.nshealth.ca/en/permalink/provcat32380
Anne M. Lipton, Cindy D. Marshall.
--New York, NY:
Springer
, c2013.
- Available Online
- View e-Book
- Location
- Online
The Common Sense Guide to Dementia for Clinicians and Caregivers provides an easy-to-read, practical, and thoughtful approach to dementia care. Written by two specialists who have cared for thousands of patients with dementia and their families, this ground-breaking title unifies the perspectives of neurology and psychiatry to meet a variety of caregiver needs. It spotlights many real-world concerns not typically covered in standard textbooks, while simultaneously presenting a more detailed med…
- Available Online
- View e-Book
- Author
- Lipton, Anne M
- Other Authors
- Marshall, Cindy D
- Responsibility
- Anne M. Lipton, Cindy D. Marshall
- Place of Publication
- New York, NY
- Publisher
- Springer
- Date of Publication
- c2013
- Physical Description
- 1 online resource (xxi, 206 p.)
- ISBN
- 9781461441632
- Subjects (MeSH)
- Caregivers
- Dementia - therapy
- Subjects (LCSH)
- Family medicine
- Neurology
- Psychiatry
- Abstract
- The Common Sense Guide to Dementia for Clinicians and Caregivers provides an easy-to-read, practical, and thoughtful approach to dementia care. Written by two specialists who have cared for thousands of patients with dementia and their families, this ground-breaking title unifies the perspectives of neurology and psychiatry to meet a variety of caregiver needs. It spotlights many real-world concerns not typically covered in standard textbooks, while simultaneously presenting a more detailed medical perspective than typical caregiver manuals. This handy title offers expert guidance for the clinical management of dementia and compassionate support of patients and families. Designed to enhance the physician-caregiver interaction and liberally illustrated with case examples, The Common Sense Guide espouses general principles of dementia care that apply across the stages and spectrum of this illness, including non-Alzheimer's types of dementia, in addition to Alzheimer's disease. Clinicians, family members, and other caregivers will find this volume useful from the moment that symptoms of dementia emerge. The authors place an emphasis on caring for the caregiver as well as the patient. Essential topics include how to find the right clinician, make the most of a doctor's visit, and avert a crisis - or manage one that can't be avoided. Sometimes difficult considerations, such as driving, financial management, legal matters, long-term placement, and end-of-life care, are faced head-on. Tried, true, and time-saving tips are explained in terms of what works - and what doesn't - with regard to clinical evaluation, medications, behavioral measures, and alternate therapies. Medical, nursing, and allied health care professionals will undoubtedly turn to this unique overview as a vital resource and mainstay of clinical dementia care, as well as a valuable recommendation for family caregivers.
- Contents
- 1. What Is Dementia? -- Part I: Start of Care -- 2. Signposts: What to Look for and When to Seek Help -- 3. Finding Help -- 4. Preparing for a Visit to the Doctor -- 5. Making the Most of the Doctor’s Visit -- Part II: Common Sense Dementia Care -- 6. The Seven Common Senses of Dementia Care -- 7. Caring for the Caregiver -- 8. Dementia Medications -- 9. Alternative Therapies in Dementia -- 10. Alcohol and Other Substances -- Part III: Mood and Behavior -- 11. Mood Issues in Dementia -- 12. Psychosis -- 13. Dealing with Problem Behaviors in Dementia -- Part IV: Additional Considerations in Dementia Care -- 14. Legal and Financial Matters -- 15. Selecting Level of Care -- 16. Looking Ahead: The Later Stages.
- Format
- e-Book
- Publication Type
- Popular Works
- Location
- Online
Congenital Hyperinsulinism : A Practical Guide to Diagnosis and Management
https://libcat.nshealth.ca/en/permalink/provcat44051
Diva D. De León-Crutchlow, Charles A. Stanley, editors.
--Cham:
Humana Press
, 2019.
- Available Online
- View e-Book
- Location
- Online
This unique book is a practical guide for the clinician faced with the challenge of diagnosing and managing neonates, infants and children with congenital hyperinsulinism (HI), within the framework of pathophysiology and molecular genetics. Major advances have been made in HI research over the past two decades, and with this better understanding of the molecular genetics of HI, a “personalized” approach to management according to the type of hyperinsulinism, and particularly according to the li…
- Available Online
- View e-Book
- Other Authors
- De León-Crutchlow, Diva D.
- Stanley, Charles A.
- Responsibility
- Diva D. De León-Crutchlow, Charles A. Stanley, editors
- Place of Publication
- Cham
- Publisher
- Humana Press
- Date of Publication
- 2019
- Physical Description
- 1 online resource (xv, 165 p.) : 22 illus., 12 illus. in color
- Series
- Contemporary Endocrinology
- Series Title
- Contemporary endocrinology
- ISBN
- 9783030029616
- 9783030029609 (Print ed.)
- 9783030029623 (Print ed.)
- ISSN
- 2523-3785
- Specialty
- Diabetes Mellitus
- Abstract
- This unique book is a practical guide for the clinician faced with the challenge of diagnosing and managing neonates, infants and children with congenital hyperinsulinism (HI), within the framework of pathophysiology and molecular genetics. Major advances have been made in HI research over the past two decades, and with this better understanding of the molecular genetics of HI, a “personalized” approach to management according to the type of hyperinsulinism, and particularly according to the likelihood of focal hyperinsulinism, is starting to emerge. The opening chapter discusses HI diagnosis using biochemical approaches and phenotype characterization. The various forms of HI are then presented in detail in three main categories: diazoxide-responsive, diazoxide-unresponsive and syndromic HI. Both medical and surgical management strategies are then discussed, covering imaging, histology, surgical approach, and post-operative management. Complications, such as feeding problems, and long-term outcomes, such as neurodevelopmental issues, are carefully considered in the final chapter. Practical and user-friendly, Congenital Hyperinsulinism is the go-to resource for pediatric endocrinologists, residents and fellows, general pediatricians and neonatologists.
- Contents
- Approach to the Diagnosis of Neonates and Infants with Persistent Hypoglycemia -- Diazoxide-Responsive Forms of Congenital Hyperinsulinism -- Diazoxide-Unresponsive Forms of Congenital Hyperinsulinism -- Syndromic Causes of Congenital Hyperinsulinism -- Molecular Diagnosis of Congenital Hyperinsulinism -- Medical Management of Hyperinsulinism -- 18F-DOPA PET -- Histopathology of the Pancreas in Congenital Hyperinsulinism -- Surgery for Congenital Hyperinsulinism -- Perioperative Management of Hyperinsulinism -- Management of the Child with Persistent Hypoglycemia After Surgery -- Management of Diabetes and Pancreatic Insufficiency after Pancreatectomy -- Feeding Problems in Congenital Hyperinsulinism -- Neurodevelopmental Outcomes.
- Format
- e-Book
- Location
- Online
Diffusion MRI Outside the Brain : A Case-Based Review and Clinical Applications
https://libcat.nshealth.ca/en/permalink/provcat31120
Antonio Luna, Ramón Ribes, Jorge A. Soto.
--Berlin, Heidelberg:
Springer
, c2012.
- Available Online
- View e-Book
- Location
- Online
Diffusion MRI allows indirect estimation of the perfusion and cellularity of normal and abnormal tissues and has conventionally been used in the brain in order to evaluate ischemia, tumors, and other conditions. Application in other parts of the body has been hampered by the occurrence of motion and susceptibility artifacts. However, recent advances in MR technology are overcoming these hurdles, allowing the use of diffusion MRI in organs outside the brain. In this book, the authors present cas…
- Available Online
- View e-Book
- Author
- Luna, Antonio
- Other Authors
- Ribes, Ramón
- Soto, Jorge A
- Responsibility
- Antonio Luna, Ramón Ribes, Jorge A. Soto
- Place of Publication
- Berlin, Heidelberg
- Publisher
- Springer
- Date of Publication
- c2012
- Physical Description
- 1 online resource (xxi, 400 p. : 161 ill., 69 ill. in color)
- ISBN
- 9783642210525
- Subjects (MeSH)
- Diffusion Magnetic Resonance Imaging - methods
- Diffusion Magnetic Resonance Imaging - Case Reports
- Subjects (LCSH)
- Radiology, Medical
- Diagnostic imaging
- Abstract
- Diffusion MRI allows indirect estimation of the perfusion and cellularity of normal and abnormal tissues and has conventionally been used in the brain in order to evaluate ischemia, tumors, and other conditions. Application in other parts of the body has been hampered by the occurrence of motion and susceptibility artifacts. However, recent advances in MR technology are overcoming these hurdles, allowing the use of diffusion MRI in organs outside the brain. In this book, the authors present cases drawn from daily clinical practice to illustrate the role of diffusion sequences, along with other morphological and functional MRI information, in the work-up of a variety of frequently encountered oncological and non-oncological diseases. Breast, musculoskeletal, whole-body, and other applications are covered in detail, with careful explanation of the pros and cons of diffusion MRI in each circumstance. Quantification and post-processing are discussed, and advice is provided on how to acquire state of the art images, and avoid artifacts, when using 1.5- and 3-T magnets. Applications likely to emerge in the near future, such as for screening, are also reviewed. The practical approach adopted by the authors, combined with the wealth of high-quality illustrations, ensures that this book will be of great value to practitioners.
- Contents
- [Machine generated contents note] 1. Diffusion-Weighted Imaging: Acquisition and Biophysical Basis / Javier Lafuente-Martinez -- 1.1. Diffusion-Weighted Imaging: Physical Basis and Types of Acquisition -- 1.2. Fat Suppression Techniques -- 1.2.1. Advanced Fat Suppression Techniques -- 1.3. Motion Control -- 1.4. Non-Single-Shot EPI Acquisition -- Further Reading -- 2. How to Identify and Avoid Artifacts on DWI / Javier Sanchez-Gonzalez -- 2.1. Optimization of Signal to Noise Ratio -- 2.2. Geometrical Distortion Artifacts -- 2.3. Motion Artifacts -- 2.4. Eddy Currents Artifacts -- 2.5. Fat Suppression Artifacts -- 2.6. Dielectric Shielding Artifacts -- 2.7. Tips in DWI Sequence Design for Body Applications -- Further Reading -- 3. Quantification and Postprocessing of DWI / Antonio Luna -- 3.1. Biophysical Basis -- 3.2. Estimation of Quantitative Data -- 3.2.1. ADC and eADC Estimation with Two and Multiple b-Values -- 3.2.2. Multiexponential Modeling of Diffusion -- 3.2.3. Diffusion Tensor Imaging -- 3.3. DWI Analysis and Postprocessing -- 3.3.1. Diffusion Registration -- 3.3.2. DWI Analysis and Postprocessing -- 3.3.3. ADC Analysis -- Further Reading -- 4. DWI at 3 T: Advantages, Disadvantages, Pitfalls, and Advanced Clinical Applications / Antonio Luna -- 4.1. DWI at 3 T -- 4.1.1. Advanced Clinical Applications at 3 T Magnets -- 4.2. Pitfalls in DWI -- 4.2.1. T2 Shine-Through -- 4.2.2. T2 Dark-Through -- 4.2.3. Restriction of Normal Structures -- 4.2.4. Iron Overload -- 4.2.5. Nonmalignant Lesions with Apparent Restrictions on DWI -- 4.2.6. Tumors with Low Cellular Density -- 4.3. Conclusions -- Further Reading -- 5. DWI of the Liver / Luis Luna -- 5.1. Background -- 5.2. DWI: Basic Concepts -- 5.3. DWI: Basic Sequence Design -- 5.4. Quantification -- 5.5. Other Techniques -- 5.6. Clinical Applications in Liver Disease -- 5.6.1. Focal Liver Lesion Detection -- 5.6.2. Characterization of Focal Liver Lesions -- 5.6.3. Benign Focal Liver Lesions -- 5.6.4. Malignant Focal Liver Lesions -- 5.6.5. Focal Liver Lesions in the Cirrhotic Liver -- 5.6.6. Monitoring Response to Treatment -- 5.6.7. Diffuse Liver Disease -- 5.7. Conclusions -- Further Reading -- 6. Diffusion-Weighted MR Imaging of the Pancreas / Nagaraj Holalkere -- 6.1. Introduction -- 6.2. Pancreatic Cancer -- 6.3. Cystic Masses -- 6.4. Other Applications -- 6.5. Biliary Tract -- Case 6.1 Mass-Forming Focal Pancreatitis -- Case 6.2 Pancreatic Ductal Adenocarcinoma -- Case 6.3 Serous Cystadenoma -- Case 6.4 Pancreatic Pseudocyst -- Case 6.5 Von Hippel Lindau Disease with Simple Pancreatic Cysts -- Case 6.6 Mucinous Cystadenoma -- Case 6.7 Intraductal Papillary Mucinous Neoplasm -- Case 6.8 Sclerosing Pancreatitis and Peripancreatic Collection -- Case 6.9 Hilar Cholangiocarcinoma -- Case 6.10 Acute Cholecystitis -- Further Reading -- 7. Diffusion-Weighted MR Imaging of the Renal and Adrenal Glands / Jorge A. Soto -- 7.1. Introduction -- 7.2. Technique -- 7.3. Renal DWI -- 7.4. Adrenal DWI -- Case 7.1 Papillary Cell Carcinoma -- Case 7.2 Cystic Clear Cell Carcinoma -- Case 7.3 Hemorrhagic Renal Cyst -- Case 7.4 Lymph Node Metastasis -- Case 7.5 Alternative to Contrast-Enhanced MR Imaging -- Case 7.6 Recurrent Renal Cancer -- Case 7.7 Adrenal Metastatic Lesion -- Case 7.8 Lipid Rich Adrenal Adenoma -- Case 7.9 Adrenal Hematoma -- Case 7.10 Collision Tumor -- Further Reading -- 8. Diffusion-Weighted Imaging of Prostate, Bladder, and Retroperitoneum / Antonio Luna -- 8.1. DWI of Prostate -- 8.1.1. Biophysical Basis -- 8.1.2. Technical Adjustments -- 8.1.3. DWI of the Prostate at 3 T -- 8.1.4. Benign Conditions -- 8.1.5. Cancer Detection -- 8.1.6. Cancer Localization -- 8.1.7. Tumoral Grading and Local Staging (T-Staging) -- 8.1.8. N and M Staging -- 8.1.9. Posttreatment Monitorization, Detection of Recurrence, and Prediction of Response to Treatment -- 8.1.10. Diffusion Tensor Imaging (DTI) -- 8.2. Applications of DWI in Bladder Cancer -- 8.3. Assessment of the Retroperitoneum with DWI -- Case 8.1 Evaluation of Prostatic Cancer with DWI at 3 T Magnet -- Case 8.2 Chronic Prostatitis -- Case 8.3 Central Gland Prostate Cancer -- Case 8.4 Bilateral Peripheral Prostate Cancer -- Case 8.5 Seminal Vesicles Infiltration -- Case 8.6 Monitorization of Response to Hormonal Therapy in a Patient with Prostate Cancer and Metastatic Pelvic Lymph Nodes -- Case 8.7 Local Recurrence After Brachytherapy -- Case 8.8 Local Recurrence After Radical Prostatectomy -- Case 8.9 Bladder Carcinoma -- Case 8.10 Recurrent Retroperitoneal Leiomyosarcoma -- Further Reading -- 9. Use of DWI in Female Pelvis / Jorge A. Soto -- 9.1. Introduction -- 9.2. Normal Appearance of Uterus and Cervix on DWI -- 9.3. Clinical Applications -- 9.3.1. Cervical Carcinoma -- 9.3.2. Endometrial Cancer -- 9.3.3. Myometrium -- 9.3.4. Characterization of Ovarian Masses -- 9.3.5. Assessment of Peritoneal Spread of Ovarian Carcinoma -- 9.3.6. Vagina and Vulva -- Case 9.1 Residual Cervical Carcinoma -- Case 9.2 Characterization of Endometrial Adenocarcinoma -- Case 9.3 Early Endometrial Adenocarcinoma -- Case 9.4 Adenomyosis -- Case 9.5 Uterine Leiomyoma -- Case 9.6 Adnexal Endometrioma -- Case 9.7 Ovarian Fibroma -- Case 9.8 Didelphus Uterus and Ovarian Dermoid Tumor -- Case 9.9 Ovarian Carcinoma -- Case 9.10 Vulvar Sarcoma -- Further Reading -- 10. DWI of the Breast / Antonio Luna -- 10.1. Introduction -- 10.2. Quantification in Breast DWI -- 10.3. Assessment of Breast Lesions -- 10.4. Technical Considerations of Breast DWI -- 10.5. Breast Cancer: Monitorization and Prediction of Response to Treatment with DWI -- 10.6. Breast Cancer: Screening and Staging with DWI -- Case 10.1 Invasive Ductal Carcinoma -- Case 10.2 Pure Mucinous Carcinoma -- Case 10.3 Ductal Carcinoma In Situ -- Case 10.4 Fibroadenoma -- Case 10.5 Borderline Phyllodes Tumor -- Case 10.6 Infiltrating Lobulillar Carcinoma -- Case 10.7 Invasive Lobulillar Carcinoma-IVIM Approach -- Case 10.8 Post-treatment Monitorization of Lobulillar Carcinoma -- Case 10.9 Post-treatment Monitorization of Multifocal Infiltrating Ductal Carcinoma -- Case 10.10 Recurrent Invasive Ductal Carcinoma -- Further Reading -- 11. Diffusion-Weighted Imaging of the Gastrointestinal Tract and Peritoneum / Antonio Luna -- 11.1. Malignant Lesions of GI Tract on DWI -- 11.1.1. Colorectal Carcinoma -- 11.1.2. Stomach -- 11.1.3. Small Bowel Tumors -- 11.1.4. Esophagus -- 11.2. Inflammatory Diseases -- 11.2.1. Acute Appendicitis -- 11.2.2. Acute Diverticulitis -- 11.2.3. Colitis and Enteritis -- 11.2.4. Epiploic Appendagitis and Omental Infarction -- 11.3. Evaluation of the Peritoneum -- Case 11.1 Colon Carcinoma -- Case 11.2 Gastric Carcinoma -- Case 11.3 Gastric Lymphoma -- Case 11.4 Duodenal Non-Hodgkin Lymphoma -- Case 11.5 Esophageal Carcinoma -- Case 11.6 Acute Appendicitis -- Case 11.7 Acute Diverticulitis with Abscess Formation -- Case 11.8 Crohn’s Disease-Active Inflammation -- Case 11.9 Crohn’s Disease: Fibrostenotic Stage -- Case 11.10 Peritoneal Metastases of Ovarian Carcinoma -- Further Reading -- 12. Diffusion-Weighted Imaging of Anorectal Region / Antonio Luna -- 12.1. Technical Considerations -- 12.2. Clinical Applications -- 12.2.1. Rectal Cancer Detection -- 12.2.2. Rectal Cancer Staging -- 12.2.3. Prediction of Rectal Cancer Outcome and Early Detection of Tumor Response -- 12.2.4. Posttreatment Restaging and Detection of Recurrence -- 12.2.5. Applications of DWI in Other Rectal Tumors -- 12.2.6. Inflammatory Conditions -- 12.2.7. Evaluation of Fistula-In-Ano -- 12.3. Conclusions -- Case 12.1 T1-Stage Concurrent Carcinomatous Rectal Polyps -- Case 12.2 Detection of Mesorectal Lymphadenopathies Using DWI -- Case 12.3 Prediction of Response to Neoadjuvant Treatment -- Case 12.4 Mucinous Adenocarcinoma of the Rectum with Poor Response to Treatment -- Case 12.5 Diagnosis and Monitoring of Presacral Recurrence of Rectal Carcinoma -- Case 12.6 Cystic Retrorectal Hamartoma or Tailgut Cyst -- Case 12.7 Monitorization of Response to Treatment with Imatinib of a Rectal GIST -- Case 12.8 Perirectal Abscess Secondary to Postsurgical Dehiscence of Sutures -- Case 12.9 Complicated Acute Diverticulitis -- Case 12.10 Crohn’s Disease and Perianal Fistulas -- Further Reading -- 13. Diffusion-Weighted Imaging in the Evaluation of Lung, Mediastinum, Heart, and Chest Wall / Javier Sanchez-Gonzalez -- 13.1. Introduction -- 13.2. Technical Considerations -- 13.3. Clinical Applications -- 13.3.1. Detection of Pulmonary Nodules -- 13.3.2. Pulmonary Nodule Characterization -- 13.3.3. Lung Cancer Evaluation -- 13.3.4. Staging of NSCLC with DWI -- 13.3.5. Mediastinum -- 13.3.6. Pleural Disease -- 13.3.7. Hyperpolarized Gases DWI -- 13.3.8. Chest Wall -- 13.3.9. Cardiac DWI and DTI -- 13.4. Conclusions -- Case 13.1 Synchronization on Chest DWI -- Case 13.2 Pulmonary Metastasis of Renal Cell Carcinoma -- Case 13.3 Solitary Benign Lung Nodule in an Asymptomatic Patient -- Case 13.4 Histological Grading and Prediction of Response and Posttreatment Monitorization of Lung Adenocarcinoma -- Case 13.5 Distinction of Central Bronchogenic Carcinoma and Peripheral Obstructive Atelectasis -- Case 13.6 Staging and Posttreatment Monitorization of Small Cell Lung Carcinoma -- Case 13.7 Exudative Pleural Effusion -- Case 13.8 Chronic and Occult Acute Rib Fractures -- Case 13.9 Pericardial Neuroblastoma -- Case 13.10 Ex Vivo DTI of a Pig Heart -- Further Reading -- 14. Role of DWI in the Evaluation of Tumors of the Head and Neck and in the Assessment of Lymph Nodes / Antonio Luna -- 14.1. DWI in Head and Neck Regions -- 14.1.1. Technical Aspects and Field-Strength -- 14.1.2. Characterization of Benign and Malignant Tumors -- 14.1.3. Salivary Gland Tumors -- 14.1.4. Monitoring and Predicting Response to Treatment -- 14.1.5. Detection of Recurrence -- 14.2. Evaluation of Lymph Nodes With DWI -- 14.2.1. Evaluation of Cervical Lymph Nodes -- 14.2.2. DWI of Lymph Nodes in Chest, Abdomen, and Pelvis -- Case 14.1 Intraorbital Metastasis from Retroperitoneal Leiomyosarcoma -- Case 14.2 Oropharynx Cancer with Nodal Metastases -- Case 14.3 Superficial Giant Neurofibroma -- Case 14.4 Cervical Esophageal Cancer -- Case 14.5 Recurrent Lingual Carcinoma -- Case 14.6 Cellulitis and Sialadenitis of Parotid Gland with Abscess Formation -- Case 14.7 Nodal and Local Recurrence of Parotid Squamous Cell Carcinoma -- Case 14.8 Posttreatment Monitorization and Prediction of Response to Treatment of Occult Cavum Carcinoma with Metastatic Cervical Lymph Nodes -- Case 14.9 Nodal Metastasis in the Neck from Squamous Cell Carcinoma -- Case 14.10 Vertebral, Nodal, and Peritoneal Metastases of Surgically Removed Endometrial Cancer -- Further Reading -- 15. Musculoskeletal Applications of DWI / Elda Balliu -- 15.1. DWI Sequences -- 15.2. Clinical Applications -- 15.2.1. Bone Marrow Assessment -- 15.2.2. Evaluation of the Spine -- 15.2.3. Soft-tissue Tumors -- 15.2.4. Postreatment Monitorization -- 15.2.5. Infection and Inflammation -- 15.2.6. Bone Ischemia and Trauma -- 15.2.7. Cartilage -- 15.3. New Approaches to DWI of the Musculoskeletal System -- Case 15.1 Bone Plasmacytoma -- Case 15.2 Benign Vertebral Fracture -- Case 15.3 Spondylodiscitis -- Case 15.4 Liposclerosing Myxofibrous Tumor -- Case 15.5 Chronic Popliteal Cyst -- Case 15.6 Recurrent Malignant Soft Tissue Tumor -- Case 15.7 Postsurgical Follow-up of Degenerative Disk Disease -- Case 15.8 Diabetic Osteomyelitis and Neuropathic Foot -- Case 15.9 Pelvic Abscesses Secondary to Symphysis Pubis Septic Arthritis and Osteomyelitis -- Case 15.10 Rheumatoid Arthritis -- Further Reading -- 16. Whole-Body Applications of DWI / Antonio Luna -- 16.1. General and Technical Considerations -- 16.2. Oncological Applications -- 16.3. Comparison of WB-DWI to PET and PET-CT -- 16.4. Non Oncological Applications -- Case 16.1 Multifocal Bone Tuberculosis -- Case 16.2 Bone Metastases from Breast Cancer -- Case 16.3 Bone and Lymph Node Metastases from Prostate Cancer -- Case 16.4 Multiple Myeloma -- Case 16.5 Bone Metastases from Unknown Primary -- Case 16.6 Liver and Bone Metastases from Lung Cancer -- Case 16.7 Search for the Primary Neoplasm in a Patient with Hepatic Metastases -- Case 16.8 Staging and Posttreatment Monitorization of Non-Hodgkin Lymphoma in a Pregnant Woman -- Case 16.9 Unique Spleen Metastasis from Rectal Cancer -- Case 16.10 Neurofibromatosis Type 1 -- Further Reading.
- Format
- e-Book
- Location
- Online
Disruptive Innovation through Digital Transformation : Multi-Sided Platforms of E-Health in China
https://libcat.nshealth.ca/en/permalink/provcat45561
Xue Han, Yuanyuan Wu, Jie Zheng.
--Singapore:
Springer ; Shanghai Jiao Tong University Press
, c2020.
- Available Online
- View e-Book
- Location
- Online
The book addresses the prevalent digital transformation and focuses on its significant disruption in healthcare. In light of the distinctive characteristics and evolution of the Chinese healthcare industry, private multi-sided platform (MSP) companies emerge to offer novel values and explore the industry value chain. Drawing on the management and economics literature of MSPs, this book examines the selected Chinese MSPs and compares them with the counterpart MSPs in the U.S. This analysis highl…
- Available Online
- View e-Book
- Author
- Han, Xue
- Other Authors
- Wu, Yuanyuan
- Zheng, Jie
- Responsibility
- Xue Han, Yuanyuan Wu, Jie Zheng.
- Place of Publication
- Singapore
- Publisher
- Springer ; Shanghai Jiao Tong University Press
- Date of Publication
- c2020
- Physical Description
- 1 online resource (xv, 108 p.) : 16 illus., 13 illus. in color
- ISBN
- 9789811539442
- 9789811539435 (Print ed.)
- 9789811539459 (Print ed.)
- Subjects (MeSH)
- Health Care Sector - trends
- Health Policy
- National Health Programs
- Telemedicine
- Other Subjects
- China
- Specialty
- Health Services Administration
- Abstract
- The book addresses the prevalent digital transformation and focuses on its significant disruption in healthcare. In light of the distinctive characteristics and evolution of the Chinese healthcare industry, private multi-sided platform (MSP) companies emerge to offer novel values and explore the industry value chain. Drawing on the management and economics literature of MSPs, this book examines the selected Chinese MSPs and compares them with the counterpart MSPs in the U.S. This analysis highlights how the unfolding healthcare disruption is valuable for both scholars and practitioners to understand the trends and to take effective actions. “Disruptive Innovation through Digital Transformation: Multi-Sided Platforms of E-Health in China” provides readers in the developing and developed countries with insights on how to approach the current multi-sided platform and to resolve the current problems to better serve customers and patients in the healthcare market.
- Contents
- 1. Demands for Healthcare Industry Changes Provide the Soil for Digital Transformation -- 2. Digital Transformation, Multi-sided Platforms, and Analytical Framework -- 3. Distinctive Characteristics of the Chinese Healthcare Industry -- 4. Emerging E-Health MSPs in China -- 5. Pair Comparison Between Chinese MSPs and American MSPs -- 6. Patient Engagement in Healthcare Industry Digital Transformation -- 7. Conclusions and Future Research.
- Format
- e-Book
- Location
- Online
Emerging Transplant Infections : Clinical Challenges and Implications
https://libcat.nshealth.ca/en/permalink/provcat45123
[edited by] Michele I. Morris, Camille Nelson Kotton, Camille Wolfe.
--Cham:
Springer
, c2020.
- Available Online
- View e-Book
- Location
- Online
This updateable reference work is designed to meet the needs of practitioners engaged in transplant infectious disease practice who need immediate access to current and reputable resources. It provides an overview of emerging infectious disease challenges with clinically relevant information regarding the epidemiology, diagnosis, management, and prevention of infections in solid organ and stem cell transplant recipients. Each chapter focuses on a clinical syndrome or pathogen with new or emergi…
- Available Online
- View e-Book
- Other Authors
- Morris, Michele I.
- Kotton, Camille Nelson
- Wolfe, Camille
- Responsibility
- [edited by] Michele I. Morris, Camille Nelson Kotton, Camille Wolfe
- Place of Publication
- Cham
- Publisher
- Springer
- Date of Publication
- c2020
- Physical Description
- 1 online resource
- Series Title
- Springer reference
- ISBN
- 9783030017514
- Subjects (MeSH)
- Communicable Diseases, Emerging
- Infections - microbiology
- Infection Control - methods
- Organ Transplantation - adverse effects
- Tissue Transplantation - adverse effects
- Transplants - microbiology
- Specialty
- Infectious Disease Medicine
- Transplantation
- Notes
- "Living reference work."
- Abstract
- This updateable reference work is designed to meet the needs of practitioners engaged in transplant infectious disease practice who need immediate access to current and reputable resources. It provides an overview of emerging infectious disease challenges with clinically relevant information regarding the epidemiology, diagnosis, management, and prevention of infections in solid organ and stem cell transplant recipients. Each chapter focuses on a clinical syndrome or pathogen with new or emerging implications for transplant patients. Sections include coverage on viral, bacterial, parasitic, and fungal infections, special diagnostic considerations, epidemiology, and other vital challenges physicians must face as new infections emerge. Written by international experts in emerging and transplant infections, Emerging Transplant Infections is the ultimate resource for any clinicians treating transplant patients in the era of rapidly evolving infections, including infectious disease specialists, transplant physicians, tropical medicine specialists, hematologists, oncologists, emergency physicians, hospitalists, primary care specialists, and all others.
- Contents
- Acanthamoeba, Naegleria, and Balamuthia in Transplant Patients: An Emerging Threat --Aspergillus in Solid Organ and Stem Cell Transplant Patients: Emerging Options for Diagnosis and Management -- BK Polyomavirus After Solid Organ and Hematopoietic Cell Transplantation: One Virus, Three Diseases -- Burkholderia in Transplant: Important to Speciate and Important to Treat -- Coccidioidomycosis in Transplantation -- Diarrhea in Transplant: Diagnosis and Management -- Emerging Epidemics in Transplant: Histoplasmosis, Blastomycosis, and Paracoccidioidomycosis -- Emerging Tropical Viral Infections: Dengue, Chikungunya, and Zika -- Evolving Epidemiology of Transplant Infections: Impact of Population Shifts and Climate Change -- Hepatitis B and Hepatitis D Infections in the Transplant Setting -- Hepatitis E Infections in Transplants -- HHV-6, HHV-7, and HHV-8: Forgotten Viruses in Transplantation -- Hospital Epidemiology and Infection Control in the Transplant Center -- Influenza Infections in Solid Organ and Stem Cell Transplant Recipients -- Leishmaniasis in Transplant Candidates and Recipients: Diagnosis and Management -- Malaria in Transplant Candidates and Recipients: Diagnosis and Management -- Mycoplasma and Ureaplasma Infections in Transplantation: A Big Impact Despite the Lack of a Cell Wall -- Nocardia Infections in Transplantation: Diagnosis, Management, and Impact on Outcomes -- Non-Aspergillus Fungal Infections in Transplant Patients -- Respiratory Syncytial Virus in Transplant: Stopping the Short-Term Spread, Solving the Longer-Term Problems -- Vaccination Strategies in Solid Organ and Stem Cell Transplant -- Yellow Fever: Prevention in Transplant Candidates and Emerging Treatment Data for Liver Transplant.
- Format
- e-Book
- Location
- Online
Essentials of Neurosurgical Anesthesia & Critical Care : Strategies for Prevention, Early Detection, and Successful Management of Perioperative Complications
https://libcat.nshealth.ca/en/permalink/provcat44992
Ansgar M. Brambrink, Jeffrey R. Kirsch, editor.
(Second edition)
--Cham:
Springer
, c2020.
- Available Online
- View e-Book
- Location
- Online
This comprehensive, evidence-based book is intended to serve as a reference for medical practitioners involved in the perioperative care of neurosurgical patients. Fundamental aspects of neuroanesthesiology and neurocritical care are thoroughly examined across 101 chapters, outlining key elements that are crucial to a care provider’s knowledge of the practice. These elements include specific diagnostic procedures and treatment options, concepts and applicable details of the available neurosurgi…
- Available Online
- View e-Book
- Other Authors
- Brambrink, Ansgar M.
- Kirsch, Jeffrey R.
- Responsibility
- Ansgar M. Brambrink, Jeffrey R. Kirsch, editor
- Edition
- Second edition
- Place of Publication
- Cham
- Publisher
- Springer
- Date of Publication
- c2020
- Physical Description
- 1 online resource (xxx, 671 p.) : 92 illus., 37 illus. in color
- ISBN
- 9783030174101
- 9783030174088 (Print ed.)
- 9783030174095 (Print ed.)
- Subjects (MeSH)
- Anesthesia
- Critical Care
- Neurosurgical Procedures
- Perioperative Care
- Specialty
- Anesthesiology
- Neurosurgery
- Abstract
- This comprehensive, evidence-based book is intended to serve as a reference for medical practitioners involved in the perioperative care of neurosurgical patients. Fundamental aspects of neuroanesthesiology and neurocritical care are thoroughly examined across 101 chapters, outlining key elements that are crucial to a care provider’s knowledge of the practice. These elements include specific diagnostic procedures and treatment options, concepts and applicable details of the available neurosurgical interventions and techniques, and mechanisms necessary to provide top of the line care for patients. Each chapter features definitive and distinct areas of this multi-specialty discipline, and is designed to guide the reader from problem to solution in situations that can arise in the clinical setting. Essentials of Neurosurgical Anesthesia & Critical Care, 2nd edition is a problem-oriented approach textbook that will aid a wide variety of readers in handling day-to-day issues and developments relevant to the perioperative care of neurosurgical patients.
- Contents
- Part I. Basics of Neuroanesthesia Care -- 1. The Adult Central Nervous System: Anatomy and Physiology -- 2. Neuroendocrine Physiology: Fundamentals and Common Syndromes -- 3. Cerebral Edema: Pathophysiology and Principles of Management -- 4. Management of Fluids, Electrolytes and Blood Products in Neurosurgical Patients -- 5. Key Monitoring in Neuroanesthesia: Principles, Techniques and Indications -- 6. Assessing the Anesthetized State with the Electroencephalogram -- Part II. Preoperative Concerns of the Neuroanesthesiologist -- 7. Cardiovascular Risk and Instability: Evaluation, Management and Triage -- 8. Risk Assessment and Treatment of Critical Carotid Stenosis: Suggestions for Perioperative Management -- 9. Aneurysmal Subarachnoid Hemorrhage: Risk Assessment and Perioperative Complications -- 10. Traumatic Brain Injury: Risk Assessment and Perioperative Management -- 11. Rare Neurologic Disorders and Neuromuscular Diseases: Risk Assessment and Perioperative Management -- 12. Perioperative Pharmacotherapy in Neurosurgery: Risk Assessment and Planning -- 13. Specific Considerations Regarding Consent and Communication with Patients and Family Prior to Neurosurgery -- 14. Neurotoxicity of General Anesthetics -- 15. Postoperative Neurocognitive Disorders in the Geriatric Patient -- 16. The Chronic Pain Patient Scheduled For Neurosurgery -- 17. Anesthesia for Patients Scheduled for Intraoperative Electrophysiological Monitoring -- 18. Factors Influencing Outcome in Neurosurgical Anesthesia -- 19. A Comparison of Inhaled Anesthesia and Total Intravenous Anesthesia with Target-Controlled Infusion for Neuroanesthesia -- Part III. Fundamentals of Adult Neurosurgery / Neuroanesthesia -- 20. Preparing for Anesthesia in Neurosurgical Patients -- 21. Basics of Neurosurgical Techniques and Procedures -- 22. Positioning the Patient for Neurosurgical Operations -- 23. The Intraoperative Team: Getting the Most out of Collaborative Care in the Operating Room -- 24. Next Level Communication -- Part IV. Critical Situations During Anesthesia for Brain Surgery in Adults -- 25. The “Tight Brain”: Cerebral Herniation Syndrome -- 26. Cerebral Ischemia: Options for Perioperative Neuroprotection -- 27. Massive Hemorrhage During Craniotomy: Emergency Management -- 28. Challenges During Anesthesia for Awake Craniotomy -- 29. Perioperative Challenges During Stereotactic Neurosurgery and Deep Brain Stimulator Placement -- 30. Perioperative Challenges During Posterior Fossa Surgery -- 31. Perioperative Challenges During Surgical Evacuation of Subdural and Epidural Hematomas -- 32. Perioperative Challenges During Cerebrovascular Surgery -- 33. Perioperative Challenges During Pituitary Surgery -- 34. Perioperative Challenges During Craniotomy for Space-Occupying Brain Lesions -- Part V. Critical Situations During Anesthesia for Spinal Surgery in Adults -- 35. Perioperative Challenges in Patients With Unstable Spine -- 36. Airway Crisis Associated with Cervical Spine Surgery -- 37. Spinal Cord Injury During Spinal Surgery -- 38. Blood Loss During Spinal Surgery -- 39. Coagulopathy in Spinal Surgery -- 40. Postoperative Visual Loss Following Spinal Surgery -- Part VI. Critical Situations During Anesthesia for Other Procedures in Adult Neurosurgery -- 41. Perioperative Challenges During Diagnostic and Perioperative Magnetic Resonance Imaging (MRI) -- 42. Perioperative Challenges During Electro Convulsive Therapy (ECT) -- 43. Perioperative Challenges During Carotid Artery Revascularization -- VII. Specific Perioperative Concerns in Adult Neuroanesthesia -- 44. Venous Air Embolism During Neurosurgery -- 45. Arterial Hypotension, Hypertension -- 46. Hyperthermia and Hypothermia During Neurosurgical Procedures -- 47. Challenges Associated with Perioperative Monitoring During Neurosurgery -- 48. Unintended Wake-up During Neurosurgery -- 49. Cardiac Arrest/Code -- 50. Arousal from Anesthesia: Failure to Emerge -- 51. Communication Challenges During the Perioperative Period -- Part VIII. Fundamentals of Pediatric Neurosurgery and Neuroanesthesia -- 52. Anatomy and Physiology of the Central Nervous System in Children -- 53. Pediatric Anesthetic Care Requirements -- 54. The Pediatric Airway in Neurosurgery -- 55. Specific Aspects of Positioning, Fluids, Glucose Control and Temperature Management -- Part IX. Critical Situations During Anesthesia for Pediatric Neurosurgery -- 56:Challenges During Surgery for Hydrochephalus -- 57. Challenges During Surgery for Traumatic Brain Injury in Children and Adults -- 58. Challenges During Surgery for Meningomyelocele and Encephalomyelocele -- 59. Challenges During Cranial Decompression -- 60. Challenges During Surgery for Craniosynostosis and Craniofacial Surgery -- 61. Challenges During Tumor Surgery in Children and Infants -- 62. Challenges During Surgery for Vascular Anomalies in Pediatrics -- 63. Challenges During Epilepsy Surgery in Pediatric Patients -- 64. Challenges During Pediatric Endoscopic Neurosurgery -- 65. Challenges During Diagnostic and Perioperative Imaging in Children with Brain Pathology -- Part X. Postoperative Concerns in Pediatric Neuroanesthesia -- 66. Emergence from Anesthesia Following Pediatric Neurosurgery -- 67. Postanesthesia Care Unit Risks Following Pediatric Neurosurgery -- 68. Intensive Care Risks of Pediatric Neurosurgery -- Part XI. Fundamentals of Interventional Neuroradiology -- 69. Radiation Safety in Interventional Neuroradiology -- 70. Understanding Basic Techniques and Procedures in Interventional Neuroradiology -- 71. Basics of Image Interpretation in Interventional Neuroradiology -- Part XII. Specific Concerns Regarding Anesthesia for Interventional Neuroradiology -- 72. Procedural Challenges in Interventional Neuroradiology -- 73. Anesthesiological Challenges During Neuroradiological Interventions -- 74. Specific Challenges during Neuroradiologic Interventions in Pediatric Patients -- Part XIII. Challenges During Postoperative Anesthesia Care After Neurosurgery -- 75. Surgical Emergencies After Neurosurgery -- 76. Postoperative Respiratory Complications -- 77. Neurologic Emergencies After Neurosurgery -- 78. Hemodynamic Complications After Neurosurgery -- 79. Endocrinologic Emergencies After Neurosurgery -- 80. Postoperative Paralysis, Skin Lesions and Corneal Abrasions After Neurosurgery -- 81. Postoperative Pain Management in Patients After Neurosurgical Operations -- 82. Management of Postoperative Nausea and Vomiting After Neurosurgery -- 83. The Intrahospital Transport of Neurosurgical Patients -- Part XIV. Challenges in Neurocritical Care of Neurosurgical Patients -- 84. Altered Mental Status in Neurosurgical Critical Care -- 85. Cerebrovascular Vasospasm, Normal Pressure Breakthrough Edema, Posterior Reversible Encephalopathy Syndrome (PRES) in Neurosurgical Critical Care -- 86. Sedation, Analgesia, and Neuromuscular Blockade in Neurosurgical Critical Care -- 87. Airway and Pulmonary Management in Neurosurgical Critical Care -- 88. Myocardial and Vascular Management in Neurosurgical Critical Care -- 89. Nutrition and Glucose -- 90. Fluid and Electrolyte Management in Neurosurgical Critical Care -- 91. Temperature Management in Neurosurgical Critical Care -- 92. Coagulation Management in Neurosurgical Critical Care -- 93. Gastrointestinal Hemorrhage in Neurosurgical Critical -- 94. Intracranial Monitors in Neurosurgical Critical Care -- 95. Central Nervous System Infection in Neurosurgical Critical Care -- 96. Antiepileptic Drug Therapy in Neurosurgical Critical Care -- 97. Withdrawal of Mechanical Ventilation in Neurosurgical Critical Care -- 98. Brain Death in Neurosurgical Critical Care -- 99. Organ Donation -- 100. Interaction with Family and Friends in Neurosurgical Critical Care.
- Format
- e-Book
- Location
- Online
Ghrelin in Health and Disease
https://libcat.nshealth.ca/en/permalink/provcat31026
Roy G. Smith, Michael O. Thorner, editors.
--New York, NY:
Humana Press
, c2012.
- Available Online
- View e-Book
- Location
- Online
Ghrelin, the endogenous ligand for the growth hormone secretagogue (GHS) receptor, is critical in the control of food intake and energy balance. The ghrelin receptors are now known to have important physiological properties as modulators of growth hormone release, appetite, glucose homeostasis, metabolism, immune function, neurotransmitter activity, cognitive function and neurodegeneration. Bringing all of this information together in the first comprehensive text on the topic, Ghrelin in Health…
- Available Online
- View e-Book
- Other Authors
- Smith, Roy G
- Thorner, Michael O
- Responsibility
- Roy G. Smith, Michael O. Thorner, editors
- Place of Publication
- New York, NY
- Publisher
- Humana Press
- Date of Publication
- c2012
- Physical Description
- 1 online resource (xiv, 290 p. : 44 ill., 3 ill. in color)
- Series Vol.
- v. 10
- Series Title
- Contemporary endocrinology (Totowa, N.J.)
- ISBN
- 9781617799037
- Subjects (MeSH)
- Ghrelin - metabolism
- Ghrelin - physiology
- Subjects (LCSH)
- Nutrition
- Endocrinology
- Abstract
- Ghrelin, the endogenous ligand for the growth hormone secretagogue (GHS) receptor, is critical in the control of food intake and energy balance. The ghrelin receptors are now known to have important physiological properties as modulators of growth hormone release, appetite, glucose homeostasis, metabolism, immune function, neurotransmitter activity, cognitive function and neurodegeneration. Bringing all of this information together in the first comprehensive text on the topic, Ghrelin in Health and Disease provides a state-of-the-art synthesis of the latest work in this area for physicians and physician-scientists. This volume addresses the unique property of ghrelin as a modulator of function. Such a property provides potential utility for safe intervention in a wide variety of disease states. Indeed as we learn more about the basic physiology of ghrelin, the potential for treating new disease targets emerge requiring validation in the clinic. Each chapter in this volume is authored by a leading investigator in the field. The introductory chapter sets the background for the book and provides a superb overview of the relevance of ghrelin to physiology, describing how the discovery of ghrelin has prompted us to completely rethink traditional physiology. The authors conclude their chapters by critically addressing the future translational aspects of ghrelin biology and outlining what key basic research and clinical questions remain to be addressed. An invaluable resource, Ghrelin in Health and Disease distinguishes itself as the first comprehensive title covering all of the molecular and clinical issues relating to ghrelin and advancing our clinical understanding of obesity, growth, and reproductive pathogenesis.
- Contents
- [Machine generated contents note] 1. Ghrelin: A History of Its Discovery / Johannes D. Veldhuis -- 2. Enzymatic Processing of Ghrelin Precursor / Kenji Kangawa -- 3. Ghrelin’s Novel Signaling in Islet ß-Cells to Inhibit Insulin Secretion and Its Blockade As a Promising Strategy to Treat Type 2 Diabetes / Toshihiko Yada -- 4. Gastric Ghrelin in the Regulation of Appetite and Metabolism / Felipe F. Casanueva -- 5. Ghrelin Regulation of AMPK in the Hypothalamus and Peripheral Tissues / Marta Korbonits -- 6. Ghrelin: Neuropeptide Regulator of Metabolism / Michael Alexander Cowley -- 7. GOAT and the Regulation of Energy and Glucose Homeostasis / Jenny Tong -- 8. Ghrelin Regulation of Sleep, Circadian Clock, and Body Temperature / Levente Kapas -- 9. Ghrelin Regulation of Learning, Memory, and Neurodegeneration / Tamas L. Horvath -- 10. Ghrelin Antagonism: A Potential Therapeutic Target for Addictive Behaviour Disorders / Suzanne L. Dickson -- 11. Ghrelin Receptor Agonists in Cachexia of Human Aging / Michael O. Thorner -- 12. Use of Ghrelin and Ghrelin Receptor Agonists in Cancer- and Chemotherapy-Induced Cachexia / Jose M. Garcia -- 13. Ghrelin in Cachexia Associated with End-Stage Renal Disease / Stephen Bloom -- 14. Ghrelin Suppression of Autoimmune Encephalomyelitis / Takashi Yamamura -- 15. Physiological Roles of Des-Acyl Ghrelin / Aart J. van der Lely -- 16. Ghrelin Receptor (GHSR1a), But Not Ghrelin, Is Essential for Dopamine Receptor-2 (DRD2) Agonist-Induced Anorexia / Roy G. Smith.
- Format
- e-Book
- Location
- Online
Healthy Cities : The Theory, Policy, and Practice of Value-Based Urban Planning
https://libcat.nshealth.ca/en/permalink/provcat41233
Evelyne de Leeuw, Jean Simos, editors.
--New York, NY:
Springer
, 2017.
- Available Online
- View e-Book
- Location
- Online
This forward-looking resource recasts the concept of healthy cities as not only a safe, pleasant, and green built environment, but also one that creates and sustains health by addressing social, economic, and political conditions. It describes collaborations between city planning and public health creating a contemporary concept of urban governance: democratically-informed process that embraces values like equity. Models, critiques, and global examples illustrate institutional change, community…
- Available Online
- View e-Book
- Other Authors
- de Leeuw, Evelyne
- Simos, Jean
- Responsibility
- Evelyne de Leeuw, Jean Simos, editors
- Place of Publication
- New York, NY
- Publisher
- Springer
- Date of Publication
- 2017
- Physical Description
- 1 online resource (xxx, 515 pages) : 78 illus., 70 illus. in color
- ISBN
- 9781493966943
- 9781493966929 (print ed.)
- Subjects (MeSH)
- City Planning
- Health Policy
- Socioeconomic Factors
- Urban Health
- Abstract
- This forward-looking resource recasts the concept of healthy cities as not only a safe, pleasant, and green built environment, but also one that creates and sustains health by addressing social, economic, and political conditions. It describes collaborations between city planning and public health creating a contemporary concept of urban governance: democratically-informed process that embraces values like equity. Models, critiques, and global examples illustrate institutional change, community input, targeted assessment, and other means of addressing longstanding sources of urban health challenges. In these ambitious pages, healthy cities are rooted firmly in the worldwide movement toward balanced and sustainable urbanization, developed not to disguise or displace entrenched health and social problems, but to encourage and foster solutions. Included in the coverage: Towards healthy urban governance in the century of the city; Healthy cities emerge: Toronto, Ottawa, Copenhagen; The role of policy coalitions in understanding community participation in healthy cities projects; Health impact assessment at the local level; The logic of method for evaluating healthy cities. Plus: extended reports on healthy cities and communities in North and Latin America, Africa, Europe, Asia, Oceania, and the Middle East Healthy Cities will interest and inspire community leaders, activists, politicians, and entrepreneurs working to improve health and well-being at the local level, as well as public health and urban development scholars and professionals.
- Contents
- Part I: Healthy Cities in History -- 1. Cities and Health from the Neolithic to the Anthropocene -- 2. Equitable and Healthy City Planning: Towards Healthy Urban Governance in the Century of the City -- 3. From Health Care to the Promotion of Health: Establishing the Conditions for Healthy Communities in Canada -- 4. Healthy Cities Emerge: Toronto–Ottawa–Copenhagen -- 5. Healthy Cities Move to Maturity -- Part II: Regional World Perspectives -- 6. Healthy Cities in Africa: A Continent of Difference -- 7. Healthy Cities in the Eastern Mediterranean: From Sanitation to Comprehensive Policy -- 8. Healthy Municipalities, Cities, and Communities in Latin America: Strong Histories, Committed Futures -- 9. Healthy Cities and Communities: The North American Experience -- 10. Healthy Cities in Europe: Structured, Unique, and Thoughtful -- 11. The Diversity of Healthy Cities in Asia and the Pacific -- 12. Healthy Cities, Urbanisation, and Healthy Islands: Oceania -- Part III: Grand Healthy City Challenges and Perspectives -- 13. Wrap-Up: Values and Governance for Urban Health -- 14. The Role of Policy Coalitions in Understanding Community Participation in Healthy Cities Projects -- 15. Greening the City: The Health Evidence of Urban Nature -- 16. Local Health Planning and Governance -- 17. From Urban Projects to Healthy City Policies -- 18. A Supportive Tool for Urban Health: Health Impact Assessment at the Local Level -- 19. Futures Thinking and Healthy Cities -- 20. The Logic of Method for Evaluating Healthy Cities -- 21. Healthy Cities: A Political Project Designed to Change How Cities Understand and Deal with Health.
- Format
- e-Book
- Location
- Online
Involuntary memory
https://libcat.nshealth.ca/en/permalink/provcat27670
Mace, John H.
--Hoboken, NJ:
John Wiley & Sons
, 2008.
- Available Online
- View e-Book
- Location
- Online
- Available Online
- View e-Book
- Author
- Mace, John H.
- Place of Publication
- Hoboken, NJ
- Publisher
- John Wiley & Sons
- Date of Publication
- 2008
- ISBN
- 9780470774069
- Subjects (MeSH)
- Mental Recall
- Contents
- Involuntary memory : concept and theory / John H. Mace -- Involuntary autobiographical memories : speculations, findings, and an attempt to integrate them / Dorthe Berntsen -- Does involuntary remembering occur during voluntary remembering? / John H. Mace -- The role of involuntary memories in posttraumatic disorder and psychosis / Craig Steel and Emily A. Holmes -- Effects of age on involuntary autobiographical memories / Simone Schlagman, Lia Kvavilashvili, and Joerg Schulz -- Cues to the gusts of memory / Christopher T. Ball, John H. Mace, and Hercilia Corona -- Can we elicit involuntary autobiographical memories in the laboratory? / Christopher T. Ball -- Interaction between retrieval intentionality and emotional intensity : investigating the neural correlates of experimentally induced involuntary memories / Nicoline M. Hall -- How deliberate, spontaneous, and unwanted memories emerge in a computational model of consciousness / Bernard J. Baars, Uma Ramamurthy, and Stan Franklin -- Involuntary memories : variations on the unexpected / George Mandler.
- Format
- e-Book
- Location
- Online
Neoliberal Ebola : Modeling Disease Emergence from Finance to Forest and Farm
https://libcat.nshealth.ca/en/permalink/provcat40295
Robert G. Wallace, Rodrick Wallace, editors.
--Cham:
Springer
, c2016.
- Available Online
- View e-Book
- Location
- Online
This book compiles five papers modeling the effects of neoliberal economics on the emergence of Ebola and its aftermath. The multidisciplinary teams represented here place both Ebola Makona, the Zaire Ebola virus variant that has infected 28,000 in West Africa, and Ebola Reston, which is currently emerging in industrial hog farms in the Philippines and China, within a multi-plank modeling framework. This volume proposes an alternate science of disease and an adjunct program of interventions use…
- Available Online
- View e-Book
- Other Authors
- Wallace, Robert G
- Wallace, Rodrick
- Responsibility
- Robert G. Wallace, Rodrick Wallace, editors
- Place of Publication
- Cham
- Publisher
- Springer
- Date of Publication
- c2016
- Physical Description
- 1 online resource (xv, 96 p. : 12 illus., 4 illus. in color)
- ISBN
- 9783319409405
- 9783319409399 (print ed.)
- Subjects (MeSH)
- Communicable Diseases, Emerging
- Disease Outbreaks - economics
- Disease Transmission, Infectious
- Ecological and Environmental Phenomena
- Hemorrhagic Fever, Ebola - economics
- Hemorrhagic Fever, Ebola - epidemiology
- Models, Biological
- Socioeconomic Factors
- Abstract
- This book compiles five papers modeling the effects of neoliberal economics on the emergence of Ebola and its aftermath. The multidisciplinary teams represented here place both Ebola Makona, the Zaire Ebola virus variant that has infected 28,000 in West Africa, and Ebola Reston, which is currently emerging in industrial hog farms in the Philippines and China, within a multi-plank modeling framework. This volume proposes an alternate science of disease and an adjunct program of interventions useful to researchers and public health officials alike.
- Contents
- Did Ebola emerge in West Africa by a policy-driven phase change in agroecology? -- Ebola in the hog sector: Modeling pandemic emergence in commodity livestock -- Did neoliberalizing West African forests produce a vaccine-resistant Ebola? -- Introducing pandemic control theory -- The social amplification of pandemics and other disasters.
- Format
- e-Book
- Location
- Online
Neuroendocrine Tumors in Real Life : From Practice to Knowledge
https://libcat.nshealth.ca/en/permalink/provcat43276
Annamaria Colao, Antongiulio Faggiano, Wouter de Herder, editors.
--Cham:
Springer
, c2018.
- Available Online
- View e-Book
- Location
- Online
This book on neuroendocrine tumors (NETs) aims to present, in a clear and innovative manner, a broad topic that is still unevenly and in some respects poorly delineated. The novel feature is the nature of the focus on the principles of prognosis, diagnosis, and therapy, which are outlined on the basis of well-defined clinical scenarios described with the aid of high-quality images and illustrations. The salient observations to emerge from the reported clinical cases are clearly summarized, taki…
- Available Online
- View e-Book
- Other Authors
- Colao, Annamaria
- Faggiano, Antongiulio
- de Herder, Wouter
- Responsibility
- Annamaria Colao, Antongiulio Faggiano, Wouter de Herder, editors
- Place of Publication
- Cham
- Publisher
- Springer
- Date of Publication
- c2018
- Physical Description
- 1 online resource (xvii, 349 p.) : 74 illus., 62 illus. in color
- ISBN
- 9783319590240
- 9783319590226 (print ed.)
- 9783319590233 (print ed.)
- 9783319865348 (print ed.)
- Subjects (MeSH)
- Neuroendocrine Tumors - diagnosis
- Neuroendocrine Tumors - therapy
- Specialty
- Endocrinology
- Medical Oncology
- Neurology
- Abstract
- This book on neuroendocrine tumors (NETs) aims to present, in a clear and innovative manner, a broad topic that is still unevenly and in some respects poorly delineated. The novel feature is the nature of the focus on the principles of prognosis, diagnosis, and therapy, which are outlined on the basis of well-defined clinical scenarios described with the aid of high-quality images and illustrations. The salient observations to emerge from the reported clinical cases are clearly summarized, taking into account evidence from the literature and the available guidelines. All of the significant prognostic factors—histopathological, molecular, and imaging--and current diagnostic and therapeutic strategies for the major NETs (stomach, pancreas, ileum, appendix, bronchus) are covered. In addition, in the introductory part of the book the reader will find information on basic aspects including epidemiology, classification, and underlying biological mechanisms. Neuroendocrine Tumors in Real Life will be of interest to all specialists involved in the management of NETs; it will provide the experienced with important updates and equip trainees and students with a firm understanding of key concepts.
- Contents
- I. General Remarks -- 1. Epidemiology of Neuroendocrine Tumours: By Site of Tumour and by Geographical Area -- 2. Pathological Classification: GEP, TNET, and Rare Forms -- 3. The Molecular Biology of NET: Current Status and Evaluation of Biomarkers for Prediction and Prognosis -- 4. Tumor Staging TNM -- II. Clinical Cases and Their Implications (From Clinical Practice to Guidelines) -- 5. Prognostic Factors: Grading (Ki-67 Index) -- 6. Prognostic Factors: Molecular Pathway – Somatostatin Receptors -- 7. Prognostic Factors: Molecular Pathway – Oncogene (mTOR) -- 8. Prognostic Factors: Molecular Pathway – Tumour Suppressor Gene (MEN1) -- 9. Prognostic Factors: Nuclear Medicine Imaging (FDG PET–Octreoscan/Gallium PET) -- 10. Tumour Detection in Syndromic NET: Carcinoid Syndrome -- 11. Tumor Detection in Syndromic NET: Zollinger-Ellison Syndrome -- 12. Tumor Detection in Syndromic NET: Hypoglycemic Hyperinsulinemic Syndrome -- 13. Tumor Staging: Bronchi -- 14. Tumour Staging: Ileum -- 15. Tumor Staging: Pancreas -- 16. Therapy for Locoregional Disease: Stomach/Duodenum, Colon/Rectum -- 17. Therapy for Locoregional Disease: Pancreas -- 18. Therapy for Locoregional Disease: Ileum -- 19. Therapy for Locoregional Disease: Bronchi -- 20. Therapy for Metastatic Disease: Stomach/Duodenum, Colon/Rectum -- 21. Therapy for Metastatic Disease: Pancreas -- 22. Therapy for Metastatic Disease: Ileum -- 23. Therapy for Metastatic Disease: Bronchi -- 24. Therapy for Metastatic Disease with Unknown Primary Tumor -- Supplementary Information.
- Format
- e-Book
- Location
- Online
Patient Surveillance After Cancer Treatment
https://libcat.nshealth.ca/en/permalink/provcat32586
Frank E. Johnson ... [et al.], editors.
--New York, NY:
Humana Press
, c2013.
- Available Online
- View e-Book
- Location
- Online
Patient Surveillance After Cancer Treatment covers the history of cancer patient surveillance after curative-intent treatment, the rationale, the methodologies used in the past and at present, the methodologies that will probably emerge in the future, the costs of surveillance, the definitions of various terms used in the field, and how those who are interested in the topic can get more information about it from the internet. The secondary focus of the book is to publicize the need for well-des…
- Available Online
- View e-Book
- Other Authors
- Johnson, Frank E
- Responsibility
- Frank E. Johnson ... [et al.], editors
- Place of Publication
- New York, NY
- Publisher
- Humana Press
- Date of Publication
- c2013
- Physical Description
- 1 online resource (xxi, 538 p. : 10 ill., 8 ill. in color)
- Series Title
- Current clinical oncology
- ISBN
- 9781603279697
- Subjects (MeSH)
- Follow-up studies
- Neoplasms - epidemiology
- Subjects (LCSH)
- Oncology
- Abstract
- Patient Surveillance After Cancer Treatment covers the history of cancer patient surveillance after curative-intent treatment, the rationale, the methodologies used in the past and at present, the methodologies that will probably emerge in the future, the costs of surveillance, the definitions of various terms used in the field, and how those who are interested in the topic can get more information about it from the internet. The secondary focus of the book is to publicize the need for well-designed, adequately powered randomized clinical trials comparing two (or more) surveillance strategies for each type of cancer.The audience includes all oncologists, cancer researchers, medical economists and policy makers in government and insurance companies, and finally, interested patients. This book is part of the Current Clinical Oncology series, which provides cutting-edge knowledge of cancer diagnosis, management, and treatment. World renowned experts share their insights in all the major fields of clinical oncology. From the fundamentals of pathophysiology to the latest developments in experimental and novel therapies, Current Clinical Oncology is an indispensable resource for today's practicing oncologist
- Contents
- 1. Overview -- 2. Introduction to Cancer Surveillance Strategies -- 3. Using Decision Analysis to Model Cancer Surveillance -- 4. Cancer Survivorship: Monitoring the Long-Term and Late Effects of Treatment -- 5. Upper Aerodigestive Tract Carcinoma -- 6. Upper Aerodigestive Tract Carcinoma Surveillance Counterpoint: Europe -- 7. Upper Aerodigestive Tract Carcinoma Surveillance Counterpoint: Japan -- 8. Upper Aerodigestive Tract Carcinoma Surveillance Counterpoint: Canada -- 9. Thyroid (Papillary, Follicular, Medullary, Hürthle Cell) Carcinoma -- 10. Thyroid (Papillary, Follicular, Medullary, Hürthle Cell) Carcinoma Surveillance Counterpoint: Australia -- 11. Thyroid (Papillary, Follicular, Medullary, Hürthle Cell) Carcinoma Surveillance Counterpoint: Japan -- 12. Lung Carcinoma -- 13. Lung Carcinoma Surveillance Counterpoint: Australia -- 14. Lung Carcinoma Surveillance Counterpoint: Japan -- 15. Lung Carcinoma Surveillance Counterpoint: Canada -- 16. Esophagus Carcinoma -- 17. Esophagus Carcinoma Surveillance Counterpoint: Australia -- 18. Esophagus Carcinoma Surveillance Counterpoint: Japan -- 19. Stomach -- 20. Stomach Carcinoma Surveillance Counterpoint: USA -- 21. Stomach Carcinoma Surveillance Counterpoint: Japan -- 22. Pancreatic Adenocarcinoma -- 23. Pancreatic Adenocarcinoma Surveillance Counterpoint: USA -- 24. Pancreatic Adenocarcinoma Surveillance Counterpoint: Europe -- 25. Pancreatic Adenocarcinoma Surveillance Counterpoint: Japan -- 26. Pancreatic Adenocarcinoma Surveillance Counterpoint: Canada -- 27. Liver and Biliary Tract Carcinoma -- 28. Liver and Biliary Tract Carcinoma Surveillance Counterpoint: Europe -- 29. Liver and Biliary Tract Carcinoma Surveillance Counterpoint: Australia -- 30. Liver and Biliary Tract Carcinoma Surveillance Counterpoint: Japan -- 31. Liver and Biliary Tract Carcinoma Surveillance Counterpoint: Canada -- 32. Colon and Rectum Carcinoma -- 33. Colon and Rectum Carcinoma Surveillance Counterpoint: USA -- 34. Colon and Rectum Carcinoma Surveillance Counterpoint: Australia -- 35. Colon and Rectum Carcinoma Surveillance Counterpoint: Japan -- 36. Colon and Rectum Carcinoma Surveillance Counterpoint: Canada -- 37. Anal Carcinoma -- 38. Anal Carcinoma Surveillance Counterpoint: USA -- 39. Anal Carcinoma Surveillance Counterpoint: Australia -- 40. Anal Carcinoma Surveillance Counterpoint: Japan -- 41. Anal Carcinoma Surveillance Counterpoint: Canada -- 42. Soft Tissue Sarcoma -- 43. Soft Tissue Sarcoma Surveillance Counterpoint: USA -- 44. Soft-Tissue Sarcoma Surveillance Counterpoint: Japan -- 45. Soft Tissue Sarcoma Surveillance Counterpoint: Canada -- 46. Osteogenic Sarcoma and Dedifferentiated Chondrosarcoma -- 47. Osteogenic Sarcoma and Dedifferentiated Chondrosarcoma Surveillance Counterpoint: Japan -- 48. Osteogenic Sarcoma and Dedifferentiated Chondrosarcoma Surveillance Counterpoint: Canada -- 49. Cutaneous Melanoma -- 50. Cutaneous Melanoma Surveillance Counterpoint: USA -- 51. Cutaneous Melanoma Surveillance Counterpoint: Australia -- 52. Cutaneous Melanoma Surveillance Counterpoint: Japan -- 53. Breast Carcinoma -- 54. Breast Carcinoma Surveillance Counterpoint: USA -- 55. Breast Carcinoma Surveillance Counterpoint: Europe -- 56. Breast Carcinoma Surveillance Counterpoint: Australia -- 57. Breast Carcinoma Surveillance Counterpoint: Japan -- 58. Endometrial Carcinoma -- 59. Endometrial Cancer Surveillance Counterpoint: USA -- 60. Endometrial Cancer Surveillance Counterpoint: USA -- 61. Carcinoma of the Endometrium Surveillance Counterpoint: Japan -- 62. Endometrial Carcinoma Surveillance Counterpoint: Canada -- 63. Cervical Carcinoma -- 64. Cervical Carcinoma Surveillance Counterpoint: USA -- 65. Cervical Carcinoma Surveillance Counterpoint: Japan -- 66. Cervical Carcinoma Surveillance Counterpoint: Canada -- 67. Vaginal and Vulvar Carcinoma -- 68. Vaginal and Vulvar Carcinoma Surveillance Counterpoint: Japan -- 69. Ovarian Carcinoma -- 70. Ovarian Carcinoma Surveillance Counterpoint: USA -- 71. Ovarian Cancer Surveillance Counterpoint: Europe -- 72. Ovarian Cancer Surveillance Counterpoint: Japan -- 73. Renal Carcinoma -- 74. Renal Carcinoma Surveillance Counterpoint: Europe -- 75. Renal Carcinoma Surveillance Counterpoint: Japan -- 76. Renal Carcinoma Surveillance Counterpoint: Canada -- 77. Urinary Bladder Carcinoma -- 78. Urinary Bladder Carcinoma Surveillance Counterpoint: Japan -- 79. Urinary Bladder Carcinoma Surveillance Counterpoint: Canada -- 80. Prostate Carcinoma -- 81. Prostate Carcinoma Surveillance Counterpoint: USA -- 82. Prostate Carcinoma Surveillance Counterpoint: USA -- 83. Prostate Carcinoma Surveillance Counterpoint: Europe -- 84. Prostate Carcinoma Surveillance Counterpoint: Japan -- 85. Prostate Carcinoma Surveillance Counterpoint: Canada -- 86. Testicle Carcinoma -- 87. Testicle Carcinoma Surveillance Counterpoint: USA -- 88. Testicle Carcinoma Surveillance Counterpoint: Australia -- 89. Testicle Carcinoma Surveillance Counterpoint: Japan -- 90. Lymphoma -- 91. Lymphoma Surveillance Counterpoint: USA -- 92. Lymphoma Surveillance Counterpoint: Japan -- 93. Lymphoma (Following Autologous Stem Cell Transplant) -- 94. Lymphoma (Following Autologous Stem Cell Transplant) Surveillance Counterpoint: Japan -- 95. Leukemia -- 96. Leukemia Surveillance Counterpoint: USA -- 97. Leukemia Surveillance Counterpoint: Japan -- 98. Multiple Myeloma -- 99. Multiple Myeloma Surveillance Counterpoint: USA -- 100. Multiple Myeloma Surveillance Counterpoint: Australia -- 101. Multiple Myeloma Surveillance Counterpoint: Japan -- 102. Multiple Myeloma Surveillance Counterpoint: Canada -- 103. Glioma of the Central Nervous System -- 104. Glioma of the Central Nervous System Surveillance Counterpoint: Europe -- 105. Glioma of the Central Nervous System Surveillance Counterpoint: Australia -- 106. Glioma of the Central Nervous System Surveillance Counterpoint: Japan.
- Format
- e-Book
- Location
- Online
Peer Review, Peer Education, and Modeling in the Practice of Clinical Ethics Consultation : The Zadeh Project
https://libcat.nshealth.ca/en/permalink/provcat43969
Stuart G. Finder, Mark J. Bliton, editors.
--Cham:
SpringerOpen
, c2018.
- Available Online
- View e-Book
- Access
- Open access
- Location
- Online
This open access book about the Zadeh Project demonstrates and explores a core question in clinical ethics: how can ethics consultants be accountable in the face of a robust plurality of ethical standpoints, especially those that underwrite practices and methods for doing ethics consultation as well as those viewpoints and values encountered in daily clinical ethics practice? Underscoring this question is the recognition that the field of clinical ethics consultation has arrived at a crucial po…
- Available Online
- View e-Book
- Other Authors
- Finder, Stuart G.
- Bliton, Mark J.
- Responsibility
- Stuart G. Finder, Mark J. Bliton, editors
- Place of Publication
- Cham
- Publisher
- SpringerOpen
- Date of Publication
- c2018
- Physical Description
- 1 online resource (xi, 228 p.) : 2 illus.
- ISBN
- 9783319909554
- 9783319909530 (Print ed.)
- 9783319909547 (Print ed.)
- 9783030081409 (Print ed.)
- Subjects (MeSH)
- Ethics, Clinical
- Ethics Consultation
- Ethics Committees, Clinical
- Peer Review, Health Care
- Specialty
- Ethics
- Abstract
- This open access book about the Zadeh Project demonstrates and explores a core question in clinical ethics: how can ethics consultants be accountable in the face of a robust plurality of ethical standpoints, especially those that underwrite practices and methods for doing ethics consultation as well as those viewpoints and values encountered in daily clinical ethics practice? Underscoring this question is the recognition that the field of clinical ethics consultation has arrived at a crucial point in its maturation. Many efforts are underway to more formally “professionalize” the field, with most aimed toward stabilizing a specific set of institutional considerations. Stretched between these institutional and practical initiatives resides a crucial set of of ethical considerations, chief among them the meaning and scope of responsibility for clinical ethics consultants. Developed around a long-form case scenario, the Zadeh Project provides a multi-layered series of “peer-reviews”: critique of the actions of the case scenario’s ethics consultant; reflection on clinical ethics method; examination of the many ways that commitments to method and practice can, and do, intersect, overlap, and alter one another. The design and format of this book thus models a key element for clinical ethics practice: the need and ability to provide careful and thoughtful explanation of core moral considerations that emerge among diverse standpoints. Specifically designed for those studying to become and those who are ethics consultants, this book, with its innovative and multi-layered approach, allows readers to share a peer-review-like experience that shows accountability to be what it is, an ethical, not merely procedural or administrative, undertaking.
- Contents
- INTRODUCTION -- The Zadeh Project – A Frame for Understanding the Generative Ideas, Formation, and Design -- PART ONE. A CLINICAL ETHICS CONSULTATION NARRATIVE -- The Zadeh Scenario -- PART TWO. CRITICAL RESPONSE TO THE ZADEH SCENARIO -- Brief Summary of the Essays in Part Two -- Critical Self-Reflection as Moral Practice: A Collaborative Meditation on Peer Review in Ethics Consultation -- Telling About Engagement Is Not Enough: Seeking the “Ethics” of Ethics Consultation in Clinical Ethics Case Reports -- Ethics Consultation for Mrs. Hamadani – A Focus on Process -- Ethics Consultation, Professional Praxis, and What it Means to Be a “Consultant" -- This May, or May Not, Be an Ethics Consultation -- PART THREE. REFLECTIONS ON METHOD IN RESPONSE TO THE ZADEH SCENARIO AND PART TWO -- Brief Summary of the Essays in Part Three -- Not Principlism nor Casuistry, Not Narrative Ethics nor Clinical Pragmatism: A Case for Proceduralism -- (Meta-) Methodological Lessons for Ethics Consultation -- Narrative and Method in Ethics Consultation -- Standardizing the Case Narrative -- PART FOUR. CRITICAL INQUIRY INTO PARTS ONE, TWO, AND THREE (ON THE WAY TOWARDS PEER REVIEW) -- Brief Summary of the Essays in Part Four -- Evaluating Clinical Ethics Support: On What Grounds Do We Make Judgments About Reports of Ethics Consultation? -- Doing Well or Doing Good in Ethics Consultation -- Peer Review and Beyond: Towards a Dialogical Approach of Quality in Ethics Support -- PART FIVE. REFLECTIVE SUMMARY AND RESPONSE -- Peer Review and Responsibility in/as/for/to Practice.
- Access
- Open access
- Format
- e-Book
- Location
- Online
The Social Determinants of Health in India : Concepts, Processes, and Indicators
https://libcat.nshealth.ca/en/permalink/provcat41999
Devaki Nambiar, Arundati Muralidharan, editors.
--Singapore:
Springer
, 2017.
- Available Online
- View e-Book
- Location
- Online
Drawing from the work of academics and practitioners from ten states across the country, this edited volume showcases and synthesises the diversity and richness of efforts to understand and act on the social determinants of health in India, the conditions in which we are born, grow, live work and age. Such an effort is salient in the current era of Sustainable Development Goals (SDG), which have foregrounded the issue of equity and the need for a comprehensive, multi-sectoral agenda for health …
- Available Online
- View e-Book
- Other Authors
- Nambiar, Devaki
- Muralidharan, Arundati
- Responsibility
- Devaki Nambiar, Arundati Muralidharan, editors
- Place of Publication
- Singapore
- Publisher
- Springer
- Date of Publication
- 2017
- Physical Description
- 1 online resource (xxvii, 226 pages) : 9 illus., 7 illus. in color
- ISBN
- 9789811059995
- 9789811059988 (print ed.)
- Subjects (MeSH)
- Health Policy
- Health Services Accessibility
- Healthcare Disparities
- Public Health
- Social Determinants of Health
- Socioeconomic Factors
- Other Subjects
- India
- Abstract
- Drawing from the work of academics and practitioners from ten states across the country, this edited volume showcases and synthesises the diversity and richness of efforts to understand and act on the social determinants of health in India, the conditions in which we are born, grow, live work and age. Such an effort is salient in the current era of Sustainable Development Goals (SDG), which have foregrounded the issue of equity and the need for a comprehensive, multi-sectoral agenda for health and development. In India, particularly in the last decade, there have been myriad efforts to more critically theorise and intervene in areas with bearing on health, like conflict, nutrition or urbanisation, or to address the concerns of vulnerable groups like women, children and the elderly. From these efforts emerge lessons of convergence for academic and policymaking institutions in India who are looking to operationalise and bring life to the SDG agenda in India and other Low and Middle Income Country settings. The book comprises eleven chapters and six short commentaries that appear in conversation with each other, as well as an annexure of validated, ready to use indicators for monitoring of social determinants of health.
- Contents
- 1. Palimpsests of ‘Social Determinants of Health’—From Historical Conceptions to Contemporary Practice in Global and Indian Public Health -- Part I: Conceptualization -- 2. Putting the ‘Social’ Back in: Social Determinants of Health as a Methodological Lens -- 3. Conceptual Issues of Conflict as a Social Determinant of Health: Explorations from Manipur -- 4. Deconstructing the Urban Transition: Conceptualization, Measurement and Mechanisms -- 5. Missing the Forest—The Significance of the Distal in Social Determinants of Health -- Part II: Operationalization -- 6. Shram Jeevani: Special Task Force Report on Women’s Labor in the Informal Economy in Bihar -- 7. Who’s in Charge of Social Determinants of Health? Understanding the Office of the Municipal Health Officer in Urban Areas -- 8. Scaling-Up a Community-Based Approach to SDH: Reflections on the SEWA Experience -- Part III: Oversight -- 9. Promoting Intersectoral Action on Menstrual Health and Hygiene Management: Arriving at a Framework and Indicators to Inform Policy and Programs -- 10. Chhattisgarh Swasth Panchayat Yojana: Convergent Community Action for Health and Its Determinants in Rural India -- 11. When People Wake up the Anganwadi—Community Monitoring and Action in Maharashtra Is Making Child Nutrition Services Accountable and Effective -- 12. Social Determinants of Maternal Health: Dead Women Talking -- 13. Weaving It Together: Concepts, Methods and Indicators -- Annexures: Indicator Registry.
- Format
- e-Book
- Location
- Online
