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Human experimentation : a guided step into the unknown

https://libcat.nshealth.ca/en/permalink/provcat53607
[by] William A. Silverman. --Oxford, EN: Oxford University Press , 1985.
Call Number
W 20.5 S872 1985
Location
IWK Health Sciences Library
Call Number
W 20.5 S872 1985
Author
Silverman, William A.
Responsibility
[by] William A. Silverman
Place of Publication
Oxford, EN
Publisher
Oxford University Press
Date of Publication
1985
Physical Description
204 p. : ill.
Series Title
Oxford medical publications
ISBN
192614991
Subjects (MeSH)
Ethics, Medical
Human Experimentation
Format
Book
Location
IWK Health Sciences Library
Copies
1
Loan Period
2 weeks
Less detail

Doing research with children

https://libcat.nshealth.ca/en/permalink/provcat53228
[by] Anne Grieg [and] Jayne Taylor. --London, England: Sage Publications , 1999.
Call Number
WS 20 G83 1999
Location
IWK Health Sciences Library
Call Number
WS 20 G83 1999
Author
Grieg, Anne
Other Authors
Taylor, Jayne
Responsibility
[by] Anne Grieg [and] Jayne Taylor
Place of Publication
London, England
Publisher
Sage Publications
Date of Publication
1999
Physical Description
175 p. : ill.
ISBN
761955895
Subjects (MeSH)
Research
Human Experimentation
Bioethics
Child
Format
Book
Location
IWK Health Sciences Library
Copies
1
Loan Period
2 weeks
Less detail

Acceptable risk in biomedical research : European perspectives

https://libcat.nshealth.ca/en/permalink/provcat40982
Sigmund Simonsen. --Dordrecht: Springer , c2012.
Available Online
View e-Book
Location
Online
Available Online
View e-Book
Author
Simonsen, Sigmund, 1972-
Responsibility
Sigmund Simonsen
Place of Publication
Dordrecht
Publisher
Springer
Date of Publication
c2012
Physical Description
1 online resource (xv, 293 p.)
Series Vol.
v. 50
Series Title
International library of ethics, law, and the new medicine
ISBN
9789400726789
9789400726772 (print ed.)
Subjects (MeSH)
Ethics, Research
Human Experimentation - ethics
Human Experimentation - legislation & jurisprudence
Risk Assessment - legislation & jurisprudence
Other Subjects
Europe
Contents
Part. I Initial Issues -- 1. Introduction -- 2. Method and Material -- 3. Initial Conceptual Clarifications -- 4. Origins of the Requirement of Proportionality -- 5. The Purpose of the Requirement of Proportionality -- Part II. Which Risks, Burdens, and Potential Benefits Are Relevant, and How Should They Be Estimated? -- 6. Introduction -- 7. Which Risks, Burdens and Potential Benefits Are Relevant? -- 8. How to Estimate Risks, Burdens, and Potential Benefits -- Part III. The Assessment of Proportionality -- 9. The Requirement of Proportionality – Initial Clarifications -- 10. Therapeutic Research -- 11. Nontherapeutic Research -- 12. Nontherapeutic Research on “Vulnerable” Participants -- 13. Non-interference with Necessary Clinical Interventions and The No Harm Rule -- 14. Especially on Randomised Clinical Trials, Including Placebo Controlled Clinical Trials -- 15. Acceptable Risks and Burdens to Others than the Participant -- 16. Later Developments During the Course of the Research -- 17. Legal Effects of the Requirement of Proportionality -- Part IV. Summary and Conclusions -- 18. Summary of Results -- 19. Recommendations -- 20. Perspectives -- Appendix A: Legal Instruments -- Appendix B: Case-Law -- Appendix C: Case Examples.
Format
e-Book
Location
Online
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Guidelines on research involving human subjects

https://libcat.nshealth.ca/en/permalink/provcat53478
Medical Research Council of Canada. --Ottawa, ON: Medical Research Council of Canada , 1987.
Call Number
W 50 M42 1987
Location
IWK Health Sciences Library
Call Number
W 50 M42 1987
Corporate Author
Medical Research Council of Canada
Place of Publication
Ottawa, ON
Publisher
Medical Research Council of Canada
Date of Publication
1987
Physical Description
65 p.
ISBN
662156374
Subjects (MeSH)
Ethics, Medical
Human Experimentation
Informed Consent
Format
Book
Location
IWK Health Sciences Library
Copies
1
Loan Period
Eo library use
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In Vivo Models of Inflammation. Volume I

https://libcat.nshealth.ca/en/permalink/provcat40557
Christopher S. Stevenson, Lisa A. Marshall, Douglas W. Morgan, editors. (2nd ed.) --Basel: Birkhäuser Verlag , c2006.
Available Online
View e-Book
Location
Online
In Vivo Models of Inflammation provides the biomedical researcher in both the pharmaceutical industry and academia with a description of the state of the art animal model systems used to emulate diseases with components of inflammation. This second edition acts as a complement to the first edition by describing and updating the standard models that are most utilized for specific disease areas. In addition, new models are included exploring emerging areas of inflammation research. The format is …
Available Online
View e-Book
Other Authors
Stevenson, Christopher S
Marshall, Lisa A
Morgan, Douglas W
Responsibility
Christopher S. Stevenson, Lisa A. Marshall, Douglas W. Morgan, editors
Edition
2nd ed.
Place of Publication
Basel
Publisher
Birkhäuser Verlag
Date of Publication
c2006
Physical Description
1 online resource (xii, 207 p.)
Series Title
Progress in inflammation research
ISBN
9783764375201
9783764375195 (print ed.)
Subjects (MeSH)
Animal Experimentation - standards
Disease Models, Animal
Inflammation
Abstract
In Vivo Models of Inflammation provides the biomedical researcher in both the pharmaceutical industry and academia with a description of the state of the art animal model systems used to emulate diseases with components of inflammation. This second edition acts as a complement to the first edition by describing and updating the standard models that are most utilized for specific disease areas. In addition, new models are included exploring emerging areas of inflammation research. The format is designed with the laboratory in mind: Both volumes provide detailed descriptions of the methodologies and uses of the most significant models. This includes current information regarding agents that demonstrate efficacy, those that do not and those that can be used as standard controls. The focus remains on those models that serve as pre-clinical correlates to human disease as well as those that represent components of the inflammatory response. Pioneering ideas and provocative comments about future directions are meant to challenge the status quo and stimulate new thinking. Therefore, new approaches to the development of future models in selected therapeutic areas have been highlighted. The focus on novel technologies that are vital for innovative in vivo research has been expanded to include chapters on the use of transgenic and gene transfer technologies, nanotechnology, and stem cells. This up-to-date reference manual helps to select the best animal model for a specific question. At the same time, this set of books continues to acknowledge the solemn responsibility in vivo research carries with it and extends the coverage of animal respect and welfare when used in experimental settings. Chapters describing current regulations in the United States, United Kingdom, and Japan address these concerns. Thus, the ultimate aim of this set of books is to provide current best practices for obtaining the maximum information from in vivo experimentation, while preserving the dignity and comfort of the animal.
Contents
Rat models of arthritis: Similarities, differences, advantages, and disadvantages in the identification of novel therapeutics -- Murine collagen induced arthritis -- Use of animal models of osteoarthritis in the evaluation of potential new therapeutic agents -- Models of inflammatory processes in cancer -- Advances in stem cell research: use of stem cells in animal models of muscular dystrophy -- Gene transfer technology -- Transgenics -- Nanotechnology: Towards the detection and treatment of inflammatory diseases -- UK legislation of in vivo aspects in inflammation research -- Japanese guidelines and regulations for scientific and ethical animal experimentation -- United States guidelines and regulations in animal experimentation.
Format
e-Book
Location
Online
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Legal aspects of research and clinical practice with children

https://libcat.nshealth.ca/en/permalink/provcat53726
prepared by Claire Bernard. --Ottawa, ON: National Council on Bioethics in Human Research , 1992.
Call Number
W 50 DC2 B47 1992
Location
IWK Health Sciences Library
Call Number
W 50 DC2 B47 1992
Author
Bernard, Claire
Corporate Author
National Council on Bioethics in Human Research
Responsibility
prepared by Claire Bernard
Place of Publication
Ottawa, ON
Publisher
National Council on Bioethics in Human Research
Date of Publication
1992
Physical Description
15 p.
ISBN
969611137
Subjects (MeSH)
Research
Bioethics
Human Experimentation
Ethics, Medical
Pediatrics
Canada
Notes
Text in English and French.
Format
Book
Publication Type
Bibliography
Location
IWK Health Sciences Library
Copies
1
Loan Period
2 weeks
Less detail

Report on research involving children

https://libcat.nshealth.ca/en/permalink/provcat54350
prepared by the Consent Panel Task Force of the National Council on Bioethics in Human Research. --[s.l.]: National Council on Bioethics in Human Research , 1992.
Call Number
W 50 DC2 R38 1992
Location
IWK Health Sciences Library
Call Number
W 50 DC2 R38 1992
Corporate Author
National Council on Bioethics in Human Research. Consent Panel Task Force
Other Authors
Canadian Paediatric Society
Responsibility
prepared by the Consent Panel Task Force of the National Council on Bioethics in Human Research
Place of Publication
[s.l.]
Publisher
National Council on Bioethics in Human Research
Date of Publication
1992
Physical Description
64 p.
ISBN
969611102
Subjects (MeSH)
Bioethics
Human Experimentation
Research
Ethics, Medical
Pediatrics
Canada
Format
Book
Location
IWK Health Sciences Library
Copies
1
Loan Period
2 weeks
Less detail

Human subjects research after the Holocaust

https://libcat.nshealth.ca/en/permalink/provcat33862
Sheldon Rubenfeld, Susan Benedict, editors ; foreword by Arthur L. Caplan. --Cham, Switzerland: Springer , c2014.
Available Online
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Location
Online
'An engaging, compelling and disturbing confrontation with evil...abook that will be transformative in its call for individual and collective moral responsibility." - Michael A. Grodin, M.D., Professor and Director, Project on Medicine and the Holocaust, Elie Wiesel Center for Judaic Studies, Boston University. Human Subjects Research after the Holocaust challenges you to confront the misguided medical ethics of the Third Reich personally, and to apply the lessons learned to contemporary human …
Available Online
View e-Book
Other Authors
Rubenfeld, Sheldon
Benedict, Susan
Responsibility
Sheldon Rubenfeld, Susan Benedict, editors ; foreword by Arthur L. Caplan
Place of Publication
Cham, Switzerland
Publisher
Springer
Date of Publication
c2014
Physical Description
1 online resource (xvi, 308 pages)
ISBN
9783319057026 (electronic bk.)
9783319057019
Subjects (MeSH)
Bioethics
Ethics, Medical
Ethical Review
Human Experimentation - ethics
National Socialism - history
Nontherapeutic Human Experimentation - history
Research Subjects
Subjects (LCSH)
Human experimentation in medicine - Moral and ethical aspects
Human experimentation in medicine - Germany - History - 20th century
Theory of Medicine/Bioethics
History of Science
History of Medicine
Human Rights
Abstract
'An engaging, compelling and disturbing confrontation with evil...abook that will be transformative in its call for individual and collective moral responsibility." - Michael A. Grodin, M.D., Professor and Director, Project on Medicine and the Holocaust, Elie Wiesel Center for Judaic Studies, Boston University. Human Subjects Research after the Holocaust challenges you to confront the misguided medical ethics of the Third Reich personally, and to apply the lessons learned to contemporary human subjects research. While it is comforting to believe that Nazi physicians, nurses, and bioscientists were either incompetent, mad, or few in number, they were, in fact, the best in the world at the time, and the vast majority participated in the government program of 'applied biology.' They were not coerced to behave as they did-they enthusiastically exploited widely accepted eugenic theories to design horrendous medical experiments, gas chambers and euthanasia programs, which ultimately led to mass murder in the concentration camps. Americans provided financial support for their research, modeled their medical education and research after the Germans, and continued to perform unethical human subjects research even after the Nuremberg Doctors' Trial. The German Medical Association apologized in 2012 for the behavior of its physicians during the Third Reich. By examining the medical crimes of human subjects researchers during the Third Reich, you will naturally examine your own behavior and that of your colleagues, and perhaps ask yourself "If the best physicians and bioscientists of the early 20th century could do evil while believing they were doing good, can I be certain that I will never do the same?" Presents relatively unknown aspects of human subjects research during the Third Reich Reveals surprising relationships between German and American human subjects research Dispels myths about Nazi human subjects research Compels introspection and self-examination by today's medical and research practitioners Addresses contemporary bioethical issues affecting vulnerable populations Brings together experts in the history of medicine during the Third Reich and thoughtful new voices.
Contents
Introduction: How Did It Go So Wrong? -- Twin Experiments at Auschwitz: A First-Person Account -- Eugenics and Racial Hygiene: Applied Research Strategies before, during, and after National Socialism -- Medical Ethics and Medical Research on Human Beings in National Socialism -- Sulfonamide Experiments on Prisoners in Nazi Concentration Camps: Coherent Scientific Rationality Combined with Complete Disregard of Humanity -- Stages of Transgression: Anatomical Research in National Socialism -- Nurses and Human Subjects Research during the Third Reich and Now -- Involuntary Abortion and Coercive Research on Pregnant Forced Laborers in National Socialism -- Abusive Medical Practices on "Euthanasia" Victims in Austria during and after World War II -- Medical Research and National Socialist Euthanasia: Carl Schneider and the Heidelberg Research Children from 1942 until 1945 -- Victims of Human Experiments and Coercive Research under National Socialism: Gender and Racial Aspects -- The White Rose: Resisting National Socialism, with an Introduction by Susan Benedict -- The Origins and Impact of the Nuremberg Doctors' Trial -- In the Shadow of Nuremberg: Unlearned Lessons from the Medical Trial -- The Ethics of Medical Experiments: Have We Learned the Lessons of Tuskegee and the Holocaust? -- Human Subjects Research during and after the Holocaust: Typhus Vaccine Development and the Legacy of Gerhard Rose -- Ethics in Space Medicine: Holocaust Beginnings, the Present, and the Future -- Reproduction Then and Now: Learning from the Past -- Promoting Clinical Research and Avoiding Bad Medicine: A Clinical Research Curriculum -- The Psychophysiology of Attribution: Why Appreciative Respect Can Keep Us Safe -- Confronting Medicine during the Nazi Period: Autobiographical Reflections -- Teaching the Holocaust to Medical Students: A Reflection on Pedagogy and Medical Ethics -- No Exceptions, No Excuses: A Testimonial.
Format
e-Book
Location
Online
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Gene transfer and the ethics of first-in-human research : lost in translation

https://libcat.nshealth.ca/en/permalink/provcat27747
Kimmelman, Jonathan. --Cambridge: Cambridge University Press , 2010.
Available Online
View e-Book
Location
Online
Available Online
View e-Book
Author
Kimmelman, Jonathan
Place of Publication
Cambridge
Publisher
Cambridge University Press
Date of Publication
2010
Physical Description
205 p.
Series Title
Cambridge medicine
ISBN
9780511642364
Subjects (MeSH)
Gene transfer techniques - ethics
Human Experimentation - ethics
Public Policy
Format
e-Book
Location
Online
Less detail

CIHR best practices for protecting privacy in health research : September 2005

https://libcat.nshealth.ca/en/permalink/provcat22288
Canadian Institutes of Health Research. --Ottawa, ON: Canadian Institutes of Health Research , 2005.
Call Number
W 20.55 .H9 C212c 2005
Location
Dickson Building
Call Number
W 20.55 .H9 C212c 2005
Corporate Author
Canadian Institutes of Health Research
Place of Publication
Ottawa, ON
Publisher
Canadian Institutes of Health Research
Date of Publication
2005
Physical Description
161 p.
ISBN
0662410564
Subjects (MeSH)
Biomedical Research - ethics
Human Experimentation - standards
Confidentiality - standards
Privacy
Format
Book
Location
Dickson Building
Loan Period
3 weeks
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Protecting study volunteers in research : a manual for investigative sites

https://libcat.nshealth.ca/en/permalink/provcat22639
Cynthia McGuire Dunn, Gary L. Chadwick. (3rd ed.) --Boston, MA: Thomson CenterWatch , c2004.
Call Number
W 20.55 .H9 D923p 2004
Location
Halifax Infirmary
Dickson Building
Call Number
W 20.55 .H9 D923p 2004
Author
Dunn, Cynthia McGuire
Other Authors
Chadwick, Gary L
Responsibility
Cynthia McGuire Dunn, Gary L. Chadwick
Edition
3rd ed.
Place of Publication
Boston, MA
Publisher
Thomson CenterWatch
Date of Publication
c2004
Physical Description
383 p.
ISBN
1930624441
9781930624443
Subjects (MeSH)
Biomedical Research - organization & administration
Human Experimentation - ethics
Human Experimentation - standards
Research Subjects - legislation & jurisprudence
Other Subjects
United States. Food and Drug Administration
Other Subjects
United States
Format
Book
Location
Halifax Infirmary
Dickson Building
Copies
2
Loan Period
3 weeks
Less detail

The Immortal life of Henrietta Lacks

https://libcat.nshealth.ca/en/permalink/provcat54548
Skloot, Rebecca. --New York, NY: Broadway Books , 2010.
Call Number
W 85 S68 2010
Location
IWK Health Sciences Library
Call Number
W 85 S68 2010
Author
Skloot, Rebecca
Other Authors
Lacks, Henrietta
Place of Publication
New York, NY
Publisher
Broadway Books
Date of Publication
2010
Physical Description
377 p.
ISBN
9.78E+12
Subjects (MeSH)
Human Experimentation
Patients - history - Biography
African Americans - Biography
United States
Format
Book
Location
IWK Health Sciences Library
Copies
1
Loan Period
2 weeks
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Sourcebook of Models for Biomedical Research

https://libcat.nshealth.ca/en/permalink/provcat28448
edited by P. Michael Conn. --Totowa, NJ: Humana Press , c2008.
Available Online
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Location
Online
Available Online
View e-Book
Author
Conn, P. Michael
Responsibility
edited by P. Michael Conn
Place of Publication
Totowa, NJ
Publisher
Humana Press
Date of Publication
c2008
ISBN
9781597452854
Subjects (MeSH)
Biomedical Research - methods
Animal Experimentation
Disease Models, Animal
Subjects (LCSH)
Biomedical research
Format
e-Book
Location
Online
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A guide to patient recruitment and retention

https://libcat.nshealth.ca/en/permalink/provcat22640
Anderson, Diana L. --Boston, MA: Thomson CenterWatch , 2004.
Call Number
W 20.55 .H9 A546g 2004
Location
Dickson Building
Halifax Infirmary
Call Number
W 20.55 .H9 A546g 2004
Author
Anderson, Diana L
Place of Publication
Boston, MA
Publisher
Thomson CenterWatch
Date of Publication
2004
Physical Description
291 p.
ISBN
193062445X
Subjects (MeSH)
Clinical Trials as Topic
Patient Selection
Research Subjects
Human Experimentation
Format
Book
Location
Dickson Building
Halifax Infirmary
Copies
2
Loan Period
3 weeks
Less detail

Laboratory animal law : legal control of the use of animals in research

https://libcat.nshealth.ca/en/permalink/provcat27677
Dolan, Kevin. --Hoboken, NJ: John Wiley & Sons , 2008.
Available Online
View e-Book
Location
Online
Available Online
View e-Book
Author
Dolan, Kevin
Place of Publication
Hoboken, NJ
Publisher
John Wiley & Sons
Date of Publication
2008
ISBN
9780470753361
Subjects (MeSH)
Animal Experimentation - legislation & jurisprudence
Ethics, Research
Laboratory Animal Science - legislation & jurisprudence
Format
e-Book
Location
Online
Less detail

Clinical trials and human research : a practical guide to regulatory compliance

https://libcat.nshealth.ca/en/permalink/provcat22768
Rozovsky, Fay A. --San Francisco, CA: Jossey-Bass , 2003.
Call Number
W 32.5 R893c 2003
Location
Dickson Building
Call Number
W 32.5 R893c 2003
Author
Rozovsky, Fay A.
Other Authors
Adams, Rodney K.
Place of Publication
San Francisco, CA
Publisher
Jossey-Bass
Date of Publication
2003
Physical Description
639 p.
ISBN
0787965707
Subjects (MeSH)
Clinical Trials as Topic - legislation & jurisprudence
Clinical Trials as Topic - standards
Ethics Committees, Research
Ethics, Research
Human Experimentation - legislation & jurisprudence
Human Experimentation - standards
Other Subjects
United States
Format
Book
Location
Dickson Building
Loan Period
3 weeks
Less detail

The Oxford textbook of clinical research ethics

https://libcat.nshealth.ca/en/permalink/provcat24550
Emanuel, Ezekiel J. --Oxford, England: Oxford University Press , 2008.
Call Number
W 20.55 .H9 O98 2008
Location
Halifax Infirmary
Call Number
W 20.55 .H9 O98 2008
Author
Emanuel, Ezekiel J
Place of Publication
Oxford, England
Publisher
Oxford University Press
Date of Publication
2008
Physical Description
827 p.
ISBN
9780195168655
Subjects (MeSH)
Human Experimentation - ethics
Ethics Committees, Research
Ethics, Research
Research Subjects - legislation & jurisprudence
Format
Book
Location
Halifax Infirmary
Loan Period
3 weeks
Less detail

The human use of animals : case studies in ethical choice

https://libcat.nshealth.ca/en/permalink/provcat23821
Beauchamp, Tom L. (2nd ed.) --Oxford, England: Oxford University Press , 2008.
Call Number
HV 4915 H918 2008
Location
Halifax Infirmary
Call Number
HV 4915 H918 2008
Author
Beauchamp, Tom L
Edition
2nd ed.
Place of Publication
Oxford, England
Publisher
Oxford University Press
Date of Publication
2008
Physical Description
287 p.
ISBN
9780195340198
Subjects (MeSH)
Animal Rights
Animal Welfare - ethics
Animal Experimentation - ethics
Bioethical Issues - Case Reports
Format
Book
Location
Halifax Infirmary
Loan Period
3 weeks
Less detail

Informed consent : a guide to the risks and benefits of volunteering for clinical trials

https://libcat.nshealth.ca/en/permalink/provcat21041
Getz, Kenneth. --Boston, MA: CenterWatch , 2002.
Call Number
W 20.55 .H9 G394i 2002
Location
Dickson Building
Call Number
W 20.55 .H9 G394i 2002
Author
Getz, Kenneth
Other Authors
Borfitz, Deborah
Place of Publication
Boston, MA
Publisher
CenterWatch
Date of Publication
2002
Physical Description
306 p.
ISBN
1930624093
Subjects (MeSH)
Research Subjects
Informed Consent
Human Experimentation - ethics
Clinical Trials as Topic - ethics
Format
Book
Location
Dickson Building
Loan Period
3 weeks
Less detail

Reflections on research involving children

https://libcat.nshealth.ca/en/permalink/provcat54329
prepared by Judith Miller for the National Council on Bioethics in Human Research. --Ottawa, ON: National Council on Bioethics in Human Research , 1993.
Call Number
W 20.5 DC2 M466 1993
Location
IWK Health Sciences Library
Call Number
W 20.5 DC2 M466 1993
Author
Miller, Judith
Responsibility
prepared by Judith Miller for the National Council on Bioethics in Human Research
Place of Publication
Ottawa, ON
Publisher
National Council on Bioethics in Human Research
Date of Publication
1993
Physical Description
various pagings
ISBN
969611161
Subjects (MeSH)
Ethics, Research
Human Experimentation - legislation & jurisprudence
Ethics, Medical
Pediatrics - legislation & jurisprudence
Child - legislation & jurisprudence
Canada
Notes
Issued also in French under title: Réflexions sur la recherche auprès des enfants.
Format
Book
Location
IWK Health Sciences Library
Copies
1
Loan Period
2 weeks
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31 records – page 1 of 2.