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Advances in Geroscience

https://libcat.nshealth.ca/en/permalink/provcat39908
Felipe Sierra, Ronald Kohanski, editors. (1st ed.) --Cham: Springer , c2016.
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This book provides the first comprehensive overview of a new scientific discipline termed Geroscience. Geroscience examines the molecular and cellular mechanisms that might explain why aging is the main risk factor for most chronic diseases affecting the elderly population. Over the past few decades, researchers have made impressive progress in understanding the genetics, biology and physiology of aging. This book presents vital research that can help readers to better understand how aging is a…
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Other Authors
Sierra, Felipe
Kohanski, Ronald
Responsibility
Felipe Sierra, Ronald Kohanski, editors
Edition
1st ed.
Place of Publication
Cham
Publisher
Springer
Date of Publication
c2016
Physical Description
1 online resource (xxiii, 622 p. : 39 illus.)
ISBN
9783319232461
9783319232454 (print ed.)
Subjects (MeSH)
Aging - physiology
Chronic Disease
Geriatrics
Risk Factors
Abstract
This book provides the first comprehensive overview of a new scientific discipline termed Geroscience. Geroscience examines the molecular and cellular mechanisms that might explain why aging is the main risk factor for most chronic diseases affecting the elderly population. Over the past few decades, researchers have made impressive progress in understanding the genetics, biology and physiology of aging. This book presents vital research that can help readers to better understand how aging is a critical malleable risk factor in most chronic diseases, which, in turn, could lead to interventions that can help increase a healthy lifespan, or "healthspan". The book begins with an analysis of the Geroscience hypothesis, as well as the epidemiological underpinnings that define aging as a candidate main risk factor for most chronic diseases. Next, each chapter focuses on one particular disease, or group of diseases, with an emphasis on how basic molecular and cellular biology might explain why aging is a major risk factor for it. Coverage in the book includes: cancer, cardiovascular disease, dementias, stroke, Parkinson's and Alzheimer's diseases, osteoporosis, arthritis, diabetes asthma, emphysema, kidney disease, vision impairment, and AIDS/HIV. It finishes with a chapter on pain in the elderly and an overview of future steps needed to bring the newly acquired knowledge into the clinic and the public at large.
Contents
The Geroscience Hypothesis: Is It Possible to Change the Rate of Aging? / Steven N. Austad -- Etiological Role of Aging in Chronic Diseases: From Epidemiological Evidence to the New Geroscience / Linda P. Fried and Luigi Ferrucci -- The Impact of Aging on Cancer Progression and Treatment / Shenghui He and Norman E. Sharpless -- The Impact of Cancer Treatments on Aging / Changhan Lee and Valter Longo -- Cardiovascular Disease and Aging / Ying Ann Chiao, Edward Lakatta, Zoltan Ungvari, Dao-Fu Dai and Peter Rabinovitch -- The Impact of Aging on Ischemic Stroke / Farida Sohrabji -- Parkinson's Disease and Aging / Julie K. Andersen -- The Role of Aging in Alzheimer's Disease / Geoffrey A. Kerchner and Tony Wyss-Coray -- Aging and the Bone-Muscle Interface / Simon Melov and Clifford J. Rosen -- Osteoporosis and Mechanisms of Skeletal Aging / Julie Glowacki and Tamara Vokes -- Osteoarthritis in the Elderly / Richard F. Loeser and Martin Lotz -- Diabetes and Aging / Nicolas Musi and Andrzej Bartke -- Renal Aging and Transplantation / John P. Higgins and Stuart K. Kim -- Asthma and Aging / Nicola A. Hanania and Paula Busse -- Aging in COPD and Idiopathic Pulmonary Fibrosis / Cecilia Sanchez -- Age-Related Macular Degeneration and Vision Impairment / Jayakrishna Ambati and Charles Wright -- HIV and Aging: Parallels and Synergistic Mechanisms Leading to Premature Disease and Functional Decline / Anna Hearps, Katherine Schafer, Kevin High and Alan Landay -- Pain in the Elderly / Roger B. Fillingim, Dennis C. Turk and Robert P. Yezierski -- The Way Forward / translation: James L. Kirkland.
Format
e-Book
Location
Online
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Behavioral neurology & neuropsychiatry

https://libcat.nshealth.ca/en/permalink/provcat25821
--Cambridge, England: Cambridge University Press , 2013.
Call Number
WL 348 B419 2013
Location
Halifax Infirmary
Call Number
WL 348 B419 2013
Other Authors
Arciniegas, David B
Anderson, C. Alan
Filley, Christopher M
Alternate Title
Behavioral neurology and neuropsychiatry
Place of Publication
Cambridge, England
Publisher
Cambridge University Press
Date of Publication
2013
Physical Description
668 p.
ISBN
9780521875011
Subjects (MeSH)
Brain Diseases - psychology
Behavior - physiology
Contents
1. Introduction / Christopher M. Filley, C. Alan Anderson, and David B. Arciniegas -- Part I. Structural and functional neuroanatomy -- 2. Behavioral neuroanatomy: brainstem, subcortical structures, limbic system, and cerebral cortex and supporting structures / C. Alan Anderson, David B. Arciniegas, Deborah A. Hall, and Christopher M. Filley -- 3. Cerebellum / Jeremy D. Schmahmann -- 4. White matter / Christopher M. Filley -- 5. Frontal-subcortical circuits / David G. Lichter -- 6. Arousal / C. Alan Anderson, Christopher M. Filley, David B. Arciniegas, and James P. Kelly -- 7. Sleep / Martin L. Reite -- 8. Attention / Joshua Cosman and Matthew Rizzo -- 9. Motivation / Brian D. Power and Sergio E. Starkstein -- 10. Perception and recognition / Benzi M. Kluger and Gila Z. Reckess -- 11. Memory / Felipe DeBrigard, Kelly S. Giovanello, and Danie I. Kaufer -- 12. Language / Mario F. Mendez -- 13. Prosody / Elliott D. Ross -- 14. Praxis / Kenneth M. Heilmen -- 15. Visuospatial function / Doron Merims and Morris Freedman -- 16. Executive function / David B. Arciniegas -- 17. Comportment / Michael Henry Rosenbloom, Oliver Freudenreich, and Bruce H. Price -- 18. Emotion / David B. Arciniegas -- 19. Personality / Site Kedia and C. Robert Cloninger -- Part II. Neurobehavioral and neuropsychiatric assessment -- 20. Neuropsychiatric evaluation / Fred Ovsiew -- 21. Neurological examination / Stuart A. Schneck -- 22. Assessment for subtle neurological signs / Igor Bombin, Celso Arango, and Robert W. Buchanan -- 23. Mental status examination / David B. Arciniegas, C. Alan Anderson, and Christopher M. Filley -- 24. Neuropsychological assessment / C. Munro Cullum -- 25. Forensic assessment / Hal S. Wortzel and Robert L. Trestman -- 26. Structural neuroimaging / Robin A. Hurley, Deborah M. Lucas, and Katherine H. Taber -- 27. Advanced neuroimaging / Deborah M. Little and David B. Arciniegas -- 28. Electroencephalography / Lauren C. Frey -- 29. Advanced electrophysiology / Donald C. Rojas -- 30. Neurotoxicology / Christopher M. Filley -- 31. Neuropathological assessment / B. K. Kleinschmidt-Demasters, Katherine L. Howard, Steven G. Ojemann, and Christopher M. Filley -- Part III. Treatments in behavioral neurology and neuropsychiatry -- 32. Principles of pharmacotherapy / Jonathan M. Silver -- 33. Rehabilitation and pharmacotherapy of cognitive impairment / David B. Arciniegas, Hal S. Wortzel, and Kimberly L. Frey -- 34. Pharmacotherapy of emotional disturbances / Steven L. Dubovsky -- 35. Pharmacotherapy of behavioral disturbances / Thomas W. McAllister and David B. Arciniegas -- 36. Psychotherapy / Lynne Fenton and Robert Feinstein -- 37. Environmental and behavioral interventions / Laura A. Flashman and Thomas W. McAllister -- 38. Procedural interventions / C. Alan Anderson and David B. Arciniegas.
Format
Book
Location
Halifax Infirmary
Copies
1
Loan Period
3 weeks
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Biomechanics of cycling

https://libcat.nshealth.ca/en/permalink/provcat33839
Rodrigo R. Bini, Felipe P. Carpes, editors. --Cham, Switzerland: Springer , c2014.
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Bicycles have been a common device to enhance physical fitness level in gyms and training centers along with solid use in competitive sport. For that reason, biomechanics of cycling has grown as a research field with many publications addressing different perspective of the interaction between the cyclist and his bicycle. The most common end point of research on biomechanics of cycling is optimization of performance and reduction of injury risk. One goal of this book is to meet the growing need…
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Other Authors
Bini, Rodrigo R.
Carpes, Felipe P.
Responsibility
Rodrigo R. Bini, Felipe P. Carpes, editors
Place of Publication
Cham, Switzerland
Publisher
Springer
Date of Publication
c2014
Physical Description
1 online resource (xv, 125 pages)
ISBN
9783319055398 (electronic bk.)
9783319055381
Subjects (MeSH)
Athletic Injuries - prevention & control
Athletic Performance
Bicycling - physiology
Biomechanical Phenomena
Subjects (LCSH)
Cycling - Physiological aspects
Biomechanics
Abstract
Bicycles have been a common device to enhance physical fitness level in gyms and training centers along with solid use in competitive sport. For that reason, biomechanics of cycling has grown as a research field with many publications addressing different perspective of the interaction between the cyclist and his bicycle. The most common end point of research on biomechanics of cycling is optimization of performance and reduction of injury risk. One goal of this book is to meet the growing need for a comprehensive presentation of contemporary knowledge on biomechanics of cycling which will positively influence the activity of cycling in a global fashion. In order to accomplish this purpose, ten chapters are presented with focus on varying methods for biomechanical analysis of cycling motion. The introduction section provides an overview of the main methods for assessment of cycling motion, including motion analysis, pedal force measurements, muscle activation, anthropometry and joint kinetics. These methods are discussed in depth in individual chapters followed by chapters on characteristics of bicycles and potential perspectives to improve their configuration in order to improve performance of cyclists and reduce their overuse injury risk. Moreover, a preliminary method to train technique in cyclists is shown. A final chapter provides authors perspective on the upcoming technology that should be effective in helping training of cyclists.
Contents
Introduction to Biomechanical Analysis for Performance Enhancement and Injury Prevention -- Measuring Pedal Forces -- Muscle Activity -- Joint Kinematics -- Kinetics and Pedaling Technique -- Non-traumatic Injuries in Cycling -- Bicycle Types and Sizes -- Optimizing Bicycle Configuration and Cyclists' Body Position to Prevent Overuse Injury Using Biomechanical Approaches -- Pedaling Technique Changes with Force Feedback Training in Competitive Cyclists: Preliminary Study -- Technology in Cycling.
Format
e-Book
Location
Online
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Breast Diseases : An Evidence-Based Pocket Guide

https://libcat.nshealth.ca/en/permalink/provcat44760
Guilherme Novita, Antônio Luiz Frasson, Eduardo Camargo Millen, Felipe Zerwes, Francisco Pimentel Cavalcante, editors. --Cham: Springer , c2019.
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Holdings
Nova Scotia Hospital: v. 1, 1990 - v. 8, 1998.
Location
Online
Available Online
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Responsibility
Guilherme Novita, Antônio Luiz Frasson, Eduardo Camargo Millen, Felipe Zerwes, Francisco Pimentel Cavalcante, editors
Place of Publication
Cham
Publisher
Springer
Date of Publication
c2019
Holdings
Nova Scotia Hospital: v. 1, 1990 - v. 8, 1998.
Physical Description
1 online resource (xx, 604 p.) : 201 illus., 131 illus. in color
ISBN
9783030136369
9783030136352 (Print ed.)
9783030136376 (Print ed.)
ISSN
1043-321X
Subjects (MeSH)
Breast Diseases
Breast Neoplasms
Breast - surgery
Specialty
Gynecology
Medical Oncology
Women's Health
Contents
BI-RADS® Classification -- Mammography -- Ultrasonography -- Magnetic Resonance Imaging -- Nuclear Medicine: Sentinel Lymph Node Detection and Radioguided Occult Lesion Localization (ROLL) -- Other Imaging Methods -- Mammographic Screening: General Population -- Special Screening Situations -- Percutaneous Biopsies: Clinical and Radiological Aspects -- Percutaneous Biopsies: Histopathological Aspects -- Histopathological Classification of Benign Lesions -- Breast Lump -- Breast Pain -- Nipple Discharge -- Gynecomastia -- Infectious Breast Diseases -- Classification of Intraductal Precursor and Proliferative Lesions -- Procedure for Cases of Intraductal and Proliferative Lesions -- Ductal Carcinoma in Situ -- Identifying High-Risk Female Patients -- Practical Aspects of Genetic Counseling: Genetic Tests to Identify Risks -- Prevention: Behavioral Measures and Habits -- Prevention: Chemoprevention (Primary Prevention of Breast Cancer) -- Prevention: Risk-Reducing Surgery -- Carcinogenesis and Natural History of Breast Cancer -- Histopathological and Immunohistochemical Classification of Invasive Breast Carcinomas -- Staging and Prognostic Factors -- Epidemiology of Breast Cancer -- Prognostic Predictors: Genetic Signatures, Adjuvant!, and PREDICT -- Mastectomy -- Breast Conserving Surgery -- Axillary Surgery and Other Regional Lymph Nodes -- Non-palpable Lesion Surgery -- Handling of Surgical Specimen -- Principles of Oncoplastic Surgery -- Partial Breast Reconstruction -- Breast Reconstruction with Implants -- Breast Reconstruction with Myocutaneous Flaps -- Autologous Fat Grafting in the Breast: Lipofilling -- Aesthetic Breast Surgery -- Early Breast Cancer -- Locally Advanced Breast Cancer -- Influence on Histologic, Immunohistochemical, and Molecular Subtypes on Therapeutics -- Inflammatory Breast Cancer -- Invasive Lobular Carcinoma Occult Breast Cancer -- Paget’s Disease -- Non-epithelial Tumors -- Pregnancy-Associated Breast Cancer -- Breast Cancer in Young Women -- Breast Cancer in Elderly Women -- Multifocal, Multicentric, and Bilateral Carcinoma -- Breast Cancer in Men -- Local Recurrence After Surgery -- Breast Cancer After Aesthetic Surgery -- Locorregional Treatment in Patients with Metastatic Breast Cancer -- Radiotherapy for Breast Cancer -- Adjuvant Hormone Therapy for Breast Cancer -- Adjuvant Chemotherapy of Breast Cancer -- Anti-HER2 Adjuvant Therapy Neoadjuvant Therapies -- Other Systemic Treatments for Breast Cancer -- Follow-Up After Breast Cancer -- Survivorship: Life After Breast Cancer -- Physical Rehabilitation After Breast Cancer Treatment -- Contraception and Infertility -- Approaching Climacteric Issues -- Metastatic Disease: Therapy and Palliative Care.
Format
e-Book
Publication Type
Handbook
Location
Online
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Emergency radiology : the requisites

https://libcat.nshealth.ca/en/permalink/provcat31518
[edited by] Jorge A. Soto, Brian C. Lucey. (2nd ed.) --Philadelphia, PA: Elsevier , c2017.
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Registration required for PDF access.
Location
Online
Get the essential tools you need to make an accurate diagnosis in the emergency department! Part of the popular Requisites series, Emergency Radiology: The Requisites delivers the conceptual, factual, and interpretive information you need for effective clinical practice in emergency radiology, as well certification and recertification review. Master core knowledge the easy and affordable way with clear, concise text enhanced by at-a-glance illustrations, boxes, and tables - all revised and enh…
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Other Authors
Soto, Jorge A
Responsibility
[edited by] Jorge A. Soto, Brian C. Lucey
Edition
2nd ed.
Place of Publication
Philadelphia, PA
Publisher
Elsevier
Date of Publication
c2017
Physical Description
1 online resource, 432 p.
Series Title
Requisites in radiology
ISBN
9780323376402
Subjects (MeSH)
Diagnostic Imaging
Emergency Medical Services
Subjects (LCSH)
Medical emergencies - Imaging
Diagnostic Imaging
Emergency Medical Services
Abstract
Get the essential tools you need to make an accurate diagnosis in the emergency department! Part of the popular Requisites series, Emergency Radiology: The Requisites delivers the conceptual, factual, and interpretive information you need for effective clinical practice in emergency radiology, as well certification and recertification review. Master core knowledge the easy and affordable way with clear, concise text enhanced by at-a-glance illustrations, boxes, and tables - all revised and enhanced with digital content to bring you up to date with today’s state of the art knowledge.
Contents
Traumatic and nontraumatic emergencies of the brain, head, and neck / Glenn Barest, Asim Z. Mian, Rohini N. Nadgir and Osamu Sakai -- Chest trauma / Ryan T. Whitesell and Laura Avery -- Abdomen trauma / Joshua W. Stuhlfaut, Christina A. LeBedis, and Jorge A. Soto -- Extremity trauma / Rathachai Kaewlai and Ajay Singh -- Extremities : nontrauma / Luis E. Diaz -- Imaging evaluation of common pediatric emergencies / Jennifer C. Talmadge, Sarah Sarvis Milla, and Sarah Dantzler Bixby -- Traumatic and nontraumatic spine emergencies / Glenn D. Barest and Margaret N. Chapman -- Nontraumatic emergency radiology of the thorax / Alejandra Duran-Mendicuti, Scott White, Salvatore Viscomi, Michael Stella, and Aaron Sodickson -- Nontrauma abdomen / Stephan W. Anderson, Brian C. Lucey, and Jorge A. Soto -- Pelvic emergencies / Brian C. Lucey -- Vascular emergencies / Russ Kuker, Carlos A. Anaya, Ana Maria Gomez, and Felipe Muner -- Emergency nuclear radiology / Anna K. Chacko and Rashmikant B. Shah.
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Format
e-Book
Location
Online
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Ghrelin in Health and Disease

https://libcat.nshealth.ca/en/permalink/provcat31026
Roy G. Smith, Michael O. Thorner, editors. --New York, NY: Humana Press , c2012.
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Location
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Ghrelin, the endogenous ligand for the growth hormone secretagogue (GHS) receptor, is critical in the control of food intake and energy balance. The ghrelin receptors are now known to have important physiological properties as modulators of growth hormone release, appetite, glucose homeostasis, metabolism, immune function, neurotransmitter activity, cognitive function and neurodegeneration. Bringing all of this information together in the first comprehensive text on the topic, Ghrelin in Health…
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Other Authors
Smith, Roy G
Thorner, Michael O
Responsibility
Roy G. Smith, Michael O. Thorner, editors
Place of Publication
New York, NY
Publisher
Humana Press
Date of Publication
c2012
Physical Description
1 online resource (xiv, 290 p. : 44 ill., 3 ill. in color)
Series Vol.
v. 10
Series Title
Contemporary endocrinology (Totowa, N.J.)
ISBN
9781617799037
Subjects (MeSH)
Ghrelin - metabolism
Ghrelin - physiology
Subjects (LCSH)
Nutrition
Endocrinology 
Abstract
Ghrelin, the endogenous ligand for the growth hormone secretagogue (GHS) receptor, is critical in the control of food intake and energy balance. The ghrelin receptors are now known to have important physiological properties as modulators of growth hormone release, appetite, glucose homeostasis, metabolism, immune function, neurotransmitter activity, cognitive function and neurodegeneration. Bringing all of this information together in the first comprehensive text on the topic, Ghrelin in Health and Disease provides a state-of-the-art synthesis of the latest work in this area for physicians and physician-scientists. This volume addresses the unique property of ghrelin as a modulator of function. Such a property provides potential utility for safe intervention in a wide variety of disease states. Indeed as we learn more about the basic physiology of ghrelin, the potential for treating new disease targets emerge requiring validation in the clinic. Each chapter in this volume is authored by a leading investigator in the field. The introductory chapter sets the background for the book and provides a superb overview of the relevance of ghrelin to physiology, describing how the discovery of ghrelin has prompted us to completely rethink traditional physiology. The authors conclude their chapters by critically addressing the future translational aspects of ghrelin biology and outlining what key basic research and clinical questions remain to be addressed. An invaluable resource, Ghrelin in Health and Disease distinguishes itself as the first comprehensive title covering all of the molecular and clinical issues relating to ghrelin and advancing our clinical understanding of obesity, growth, and reproductive pathogenesis.
Contents
[Machine generated contents note] 1. Ghrelin: A History of Its Discovery / Johannes D. Veldhuis -- 2. Enzymatic Processing of Ghrelin Precursor / Kenji Kangawa -- 3. Ghrelin’s Novel Signaling in Islet ß-Cells to Inhibit Insulin Secretion and Its Blockade As a Promising Strategy to Treat Type 2 Diabetes / Toshihiko Yada -- 4. Gastric Ghrelin in the Regulation of Appetite and Metabolism / Felipe F. Casanueva -- 5. Ghrelin Regulation of AMPK in the Hypothalamus and Peripheral Tissues / Marta Korbonits -- 6. Ghrelin: Neuropeptide Regulator of Metabolism / Michael Alexander Cowley -- 7. GOAT and the Regulation of Energy and Glucose Homeostasis / Jenny Tong -- 8. Ghrelin Regulation of Sleep, Circadian Clock, and Body Temperature / Levente Kapas -- 9. Ghrelin Regulation of Learning, Memory, and Neurodegeneration / Tamas L. Horvath -- 10. Ghrelin Antagonism: A Potential Therapeutic Target for Addictive Behaviour Disorders / Suzanne L. Dickson -- 11. Ghrelin Receptor Agonists in Cachexia of Human Aging / Michael O. Thorner -- 12. Use of Ghrelin and Ghrelin Receptor Agonists in Cancer- and Chemotherapy-Induced Cachexia / Jose M. Garcia -- 13. Ghrelin in Cachexia Associated with End-Stage Renal Disease / Stephen Bloom -- 14. Ghrelin Suppression of Autoimmune Encephalomyelitis / Takashi Yamamura -- 15. Physiological Roles of Des-Acyl Ghrelin / Aart J. van der Lely -- 16. Ghrelin Receptor (GHSR1a), But Not Ghrelin, Is Essential for Dopamine Receptor-2 (DRD2) Agonist-Induced Anorexia / Roy G. Smith.
Format
e-Book
Location
Online
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Hypothalamic-Pituitary Diseases

https://libcat.nshealth.ca/en/permalink/provcat42803
Felipe F. Casanueva, Ezio Ghigo, editors. --Cham: Springer , c2018.
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Location
Online
This book presents the state of the art in the pathophysiology, diagnosis, and therapy of hypothalamic and pituitary disorders. After an introduction devoted to the physiology of the neuroendocrine control of the hypothalamic-pituitary unit, the diverse disorders involving hormonal excess or deficiency are systematically addressed axis by axis. For each disorder, pathophysiology, clinical presentation, and management are discussed in detail. In addition, individual chapters focus on the neuroen…
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Other Authors
Casanueva, Felipe F.
Ghigo, Ezio
Responsibility
Felipe F. Casanueva, Ezio Ghigo, editors
Place of Publication
Cham
Publisher
Springer
Date of Publication
c2018
Physical Description
1 online resource (xix, 535 p.) : 54 illus., 31 illus. in color
Series Title
Springer reference
Endocrinology
ISBN
9783319444444
9783319444437 (print ed.)
ISSN
2510-1927
Subjects (MeSH)
Hypothalamic Diseases
Pituitary Diseases
Specialty
Endocrinology
Notes
"eReference"--Publisher.
Abstract
This book presents the state of the art in the pathophysiology, diagnosis, and therapy of hypothalamic and pituitary disorders. After an introduction devoted to the physiology of the neuroendocrine control of the hypothalamic-pituitary unit, the diverse disorders involving hormonal excess or deficiency are systematically addressed axis by axis. For each disorder, pathophysiology, clinical presentation, and management are discussed in detail. In addition, individual chapters focus on the neuroendocrinology of energy homeostasis and of bone metabolism, metabolic derangement secondary to pituitary dysfunction, and pituitary control of the endocrine pancreas. While the focus of the book is predominantly on pathophysiological and clinical aspects, due attention is also devoted to potential diagnostic and therapeutic innovations. The book is intended as a major reference for endocrinologists and basic and clinical scientists.
Contents
Chapter 1 Physiology of the hypothalamus pituitary unit -- Chapter 2 Physiopathology, diagnosis and treatment of GH Deficiency -- Chapter 3 Physiopathology, diagnosis and treatment of GH hypersecretion -- Chapter 4 Physiopathology, diagnosis and treatment of Non-functioning pituitary adenomas -- Chapter 5 Craniopharyngioma and Posttreatment Pituitary Dysfunction in Brain Tumors -- Chapter 6 Physiopathology, diagnosis and treatment of Functional pituitary dysfunction -- Chapter 7 Physiopathology, diagnosis and treatment of Secondary hypothyroidism -- Chapter 8 Physiopathology, diagnosis and treatment of Secondary hyperthyroidism -- Chapter 9 Physiopathology, Diagnosis, and Treatment of Secondary Female Hypogonadism -- Chapter 10 Central hypogonadism in the male: Physiopathology, diagnosis and treatment -- Chapter 11 Physiopathology, diagnosis and treatment of Hypercortisolism -- Chapter 12 Physiopathology, diagnosis and treatment of Diabetes insipidus -- Chapter 13 Physiopathology, Diagnosis and Treatment of Inappropriate ADH Secretion and Cerebral Salt Wasting Syndrome -- Chapter 14 Physiopathology, Diagnosis, and Treatment of Hyperprolactinemia -- Chapter 15 Neuroendocrinology of Energy Homeostasis -- Chapter 16 Neuroendocrine Control of Carbohydrate Metabolism -- Chapter 17 Neuroendocrinology of Bone Metabolism.
Format
e-Book
Location
Online
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Hypothalamic-Pituitary Diseases

https://libcat.nshealth.ca/en/permalink/provcat44568
edited by Felipe F. Casanueva, Ezio Ghigo. --Cham: Springer , c2017.
Available Online
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Location
Online
This book presents the state of the art in the pathophysiology, diagnosis, and therapy of hypothalamic and pituitary disorders. After an introduction devoted to the physiology of the neuroendocrine control of the hypothalamic-pituitary unit, the diverse disorders involving hormonal excess or deficiency are systematically addressed axis by axis. For each disorder, pathophysiology, clinical presentation, and management are discussed in detail. In addition, individual chapters focus on the neuroen…
Available Online
View e-Book
Other Authors
Casanueva, Felipe F.
Ghigo, Ezio
Responsibility
edited by Felipe F. Casanueva, Ezio Ghigo
Place of Publication
Cham
Publisher
Springer
Date of Publication
c2017
Physical Description
1 online resource (x, 530 p.)
Series Title
Springer reference
Endocrinology
ISBN
9783319386812
ISSN
2510-1927
Subjects (MeSH)
Hypothalamic Diseases
Pituitary Diseases
Specialty
Endocrinology
Notes
"Living reference work."
Abstract
This book presents the state of the art in the pathophysiology, diagnosis, and therapy of hypothalamic and pituitary disorders. After an introduction devoted to the physiology of the neuroendocrine control of the hypothalamic-pituitary unit, the diverse disorders involving hormonal excess or deficiency are systematically addressed axis by axis. For each disorder, pathophysiology, clinical presentation, and management are discussed in detail. In addition, individual chapters focus on the neuroendocrinology of energy homeostasis and of bone metabolism, metabolic derangement secondary to pituitary dysfunction, and pituitary control of the endocrine pancreas. While the focus of the book is predominantly on pathophysiological and clinical aspects, due attention is also devoted to potential diagnostic and therapeutic innovations. The book is intended as a major reference for endocrinologists and basic and clinical scientists.
Contents
Central Hypogonadism in the Male: Physiopathology, Diagnosis and Treatment -- Craniopharyngioma and Posttreatment Pituitary Dysfunction in Brain Tumors -- Neuroendocrine Control of Carbohydrate Metabolism -- Neuroendocrinology of Bone Metabolism -- Neuroendocrinology of Energy Homeostasis -- Physiology of the Hypothalamus Pituitary Unit -- Physiopathology, Diagnosis and Treatment of Inappropriate ADH Secretion and Cerebral Salt Wasting Syndrome -- Physiopathology, Diagnosis and Treatment of Secondary Hyperthyroidism -- Physiopathology, Diagnosis, and Treatment of Diabetes Insipidus -- Physiopathology, Diagnosis, and Treatment of Functional Pituitary Dysfunction -- Physiopathology, Diagnosis, and Treatment of GH Deficiency -- Physiopathology, Diagnosis, and Treatment of GH Hypersecretion -- Physiopathology, Diagnosis, and Treatment of Hypercortisolism -- Physiopathology, Diagnosis, and Treatment of Hyperprolactinemia -- Physiopathology, Diagnosis, and Treatment of Nonfunctioning Pituitary Adenomas -- Physiopathology, Diagnosis, and Treatment of Secondary Female Hypogonadism -- Physiopathology, Diagnosis, and Treatment of Secondary Hypothyroidism.
Format
e-Book
Location
Online
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Intraoperative Irradiation : Techniques and Results

https://libcat.nshealth.ca/en/permalink/provcat28420
edited by Leonard L. Gunderson, Christopher G. Willett, Felipe A. Calvo, Louis B. Harrison. --Totowa, NJ: Springer Science+Business Media , c2011.
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Location
Online
Available Online
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Author
Gunderson, Leonard L
Other Authors
Willett, Christopher G
Calvo, Felipe A
Harrison, Louis B
Responsibility
edited by Leonard L. Gunderson, Christopher G. Willett, Felipe A. Calvo, Louis B. Harrison
Place of Publication
Totowa, NJ
Publisher
Springer Science+Business Media
Date of Publication
c2011
Series Title
Current clinical oncology
ISBN
9781617790157
Subjects (MeSH)
Brachytherapy - methods
Intraoperative care
Radiotherapy Dosage
Subjects (LCSH)
Radiotherapy
Format
e-Book
Location
Online
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Multidisciplinary management of rectal cancer : questions and answers

https://libcat.nshealth.ca/en/permalink/provcat31155
Vincenzo Valentini, Hans-Joachim Schmoll, Cornelis J. H. Velde, editors. --Berlin, Heidelberg: Springer , c2012.
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Location
Online
This book seeks to promote an integrated approach among the various specialists involved in the management of rectal cancer with a view to ensuring that treatment is tailored appropriately to the individual patient. For ease of use, a question and answer format is employed. The focus is on those issues typically confronted during daily clinical practice in relation to risk factors, imaging, surgery, radiotherapy, and chemotherapy. The services of an outstanding panel of authors representative …
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Other Authors
Valentini, Vincenzo
Schmoll, Hans-Joachim
Velde, Cornelis J. H
Responsibility
Vincenzo Valentini, Hans-Joachim Schmoll, Cornelis J. H. Velde, editors
Place of Publication
Berlin, Heidelberg
Publisher
Springer
Date of Publication
c2012
Physical Description
1 online resource (xii, 367 p. : 98 ill., 70 ill. in color)
ISBN
9783642250057
Subjects (MeSH)
Rectal Neoplasms - therapy
Risk Factors
Subjects (LCSH)
Radiology, Medical
Radiotherapy
Oncology
Cancer - Surgery
Pathology
Abstract
This book seeks to promote an integrated approach among the various specialists involved in the management of rectal cancer with a view to ensuring that treatment is tailored appropriately to the individual patient. For ease of use, a question and answer format is employed. The focus is on those issues typically confronted during daily clinical practice in relation to risk factors, imaging, surgery, radiotherapy, and chemotherapy. The services of an outstanding panel of authors representative of the major European oncological societies have been acquired in order to formulate the questions and provide the answers. All who need assistance in addressing concerns that arise from the need for multidisciplinary management of rectal cancer will find the book to be an ideal source of helpful information.
Contents
[Machine generated contents note] Part I. Introduction -- 1. What Do We Consider Cancer of the Rectum? / Cornelis J.H. van de Velde -- 2. What Is the Ongoing Recommendation in the Management of Rectal Cancer? / Cornelis J.H. van de Velde -- Part II. Q&As on Risk Factor Identification -- 3. What Prognostic Clinical Factors Must Be Considered Before Treatment? / Claus Rodel -- 4. What Are the Relevant Imaging Factors to Optimize Treatment Decisions? / Gina Brown -- 5. What Biochemical and Molecular Biological Factors Have Greater Relevance to Treatment Decisions? / Jeroen Buijsen -- 6. Do Different Populations of Rectal Cancer Exist? / Ruud van Stiphout -- Part III. Q&As on Imaging -- 7. How Can We Identify Tumour Penetration? / Gina Brown -- 8. How Can We Identify Mesorectal Fascia Involvement? / Regina G.H. Beets-Tan -- 9. How Can We Identify Nodal Involvement? / Regina G.H. Beets-Tan -- 10. How Can We Identify Pathologic Complete Responders After Radiochemotherapy? / Lucia Leccisotti -- 11. How Can We Identify Local Relapse? / Regina G.H. Beets-Tan -- Part IV. Q&As on Radiotherapy -- 12. When Should Preoperative Short-Course Radiotherapy or Long-Course Chemoradiotherapy Be Performed? / Robert Glynne-Jones -- 13. Should We Tailor the Delineation of Pelvic Structures According to Tumor Presentation? / Vincenzo Valentini -- 14. What Is the Role of IMRT and IGRT in Rectal Cancer? / Corrie A.M. Marijnen -- 15. What Are the Dose-Volume Constraints to Reduce Late Toxicity? / Krzysztof Bujko -- 16. What Is the Contribution of Intraoperative Radiotherapy (IORT) in Tailoring Local Therapy in Primary or Recurrent Rectal Cancer? / Felipe A. Calvo -- 17. What Is the Contribution of Brachytherapy in Tailoring Local Therapy? / Arthur Sun Myint -- Part V. Q&As on Chemotherapy -- 18. Should Oxaliplatin Be Added to Preoperative Chemoradiation? / Carlo Aschele -- 19. Should Biologic Targeted Agents Be Combined with Preoperative Chemoradiation in Rectal Cancer? / Eric Van Cutsem -- 20. Should Upfront Chemotherapy Precede Preoperative Chemoradiation and Surgery? / Xabier Garcia de Albeniz -- 21. How to Achieve Long-Term Survival in Patients with Metastatic Rectal Cancer? / Hans-Joachim Schmoll -- 22. Will Adjuvant Chemotherapy Improve Outcome After Preoperative Chemoradiation? / Peter Nygren -- Part VI. Q&As on Surgery -- 23. How to Evaluate the Quality of Surgery? Suggestions for Critical Reading of Surgical and Pathological Reports / Lars Pahlman -- 24. How Is Nerve-Sparing Surgery Well Performed? / Ivan Dimitrijevic -- 25. Is Laparoscopic Rectal Surgery the Gold Standard? / Laeeq Khan -- 26. Is a Diverting Stoma Always Necessary for a Low Anterior Resection of a Rectal Cancer? / Geerard L. Beets -- 27. Will Extralevator Abdominoperineal Excision Become the New Gold Standard? / Harm Rutten -- 28. Which Patients Do Benefit from Extended Resections in Case of Locally Advanced Rectal Cancer? / Harm Rutten -- 29. Can Standard Surgical Procedure Reliably Be Avoided in Major Responders After Radio(chemo)therapy? / Gianluca Rizzo -- Part VII. Q&As on Pathology -- 30. What Is the Correct Procedure for Handling the Surgical Specimen? / Nigel Scott -- 31. What Is the Prognostic Value of (y)pT and (y)pN? / Nadine Ectors -- 32. What Is the Prognostic Value of CRM Involvement? / Iris D. Nagtegaal -- 33. What Is the Prognostic Value of TRG? / Fabio M. Vecchio -- Part VIII. Q&As on Multidisciplinary Team Management -- 34. What Are the Recommendations to Ensure a Successful Multidisciplinary Team in Rectal Cancer? / Robert Glynne-Jones -- 35. What Is the Appropriate Timetable for Tailored Follow-up? / Lars Pahlman -- 36. How Should Data Be Shared and Rapid Learning Health Care Promoted? / Philippe Lambin.
Format
e-Book
Location
Online
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