Colorectal cancer is the third most commonly diagnosed condition in oncology, affecting around 1.23 million individuals per year, according to recent statistics. Of these patients, about 50% will develop liver metastases and approximately 20% will present a stage IV disease at diagnosis. These statistics make colorectal liver metastases (CLM) an issue of major importance in current oncology. The area of CLM is subject to great and continuous advances, as its pathophysiologic mechanisms are bett…
This book is designed to present a practical and evidence-based approach to liver and pancreas surgery that will provide both experienced and novice surgeons as well as surgical trainees a resource for optimizing their outcomes. The entire perioperative spectrum of care is addressed in chapters written by an international panel of experts in the field. Initial sections discuss preoperative assessment and intervention, fluid management, and perioperative pain control. Subsequent chapters focus o…
This book discusses major changes in our understanding of the most prevalent non-orthopedic, sports-related condition – overtraining syndrome (OTS), arguing that it should be considered as the manifestation of burnout in athletes, rather than simply the result of excessive training. While the chronic adaptations of the cardiovascular and musculoskeletal systems to exercise are well documented, those of the endocrine system are less well known, and adaptations of the hormonal ranges for athletes…
This book integrates the concepts of big data analytics into mental health practice and research. Mental disorders represent a public health challenge of staggering proportions. According to the most recent Global Burden of Disease study, psychiatric disorders constitute the leading cause of years lost to disability. The high morbidity and mortality related to these conditions are proportional to the potential for overall health gains if mental disorders can be more effectively diagnosed and tr…
This third edition text has been largely rewritten to include the many important advances that have been made and the controversies that have arisen in the past years. New topics have been added including Oxygen Transport, Tissue Oxygenation Evaluation, Echocardiography in the Critically Ill, Bedside Ultrasonography, Critical Care Issues in Oncological Surgery Patients, Long-Term Outcome after Intensive Care, Therapeutic Hypothermia, Delirium, and Post-Operative Gastrointestinal Dysfunction. Ch…
The Golden Hour is a well-established concept in emergency medicine, related to the critical period of one hour after an injury, accident or trauma. This term implies that the mortality rates increase substantially if efficient care is not provided within 60 minutes after the trauma. This book is intended as a practical manual in Trauma Care within the context of the golden hour, addressing all trauma types and all body parts. Readers will find essential decision-making algorithms and protocols…