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New and Emerging Entities in Dermatology and Dermatopathology

https://libcat.nshealth.ca/en/permalink/provcat47078
Franco Rongioletti, Bruce R. Smoller. Springer , 2021.
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Responsibility
Franco Rongioletti, Bruce R. Smoller
Publisher
Springer
Date of Publication
2021
Physical Description
1 online resource (xvii, 513 pages) : illustrations
ISBN
9783030800277
Specialty
Dermatology
Pathology
Format
e-Book
Location
Online
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Tumors and Tumor-Like Lesions of Bone

https://libcat.nshealth.ca/en/permalink/provcat45214
Eduardo Santini-Araujo, Ricardo K. Kalil, Franco Bertoni, Yong-Koo Park, editors. (Second edition) --Cham: Springer , c2020.
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This updated second edition of a successful book provides essential, internationally applicable information in the area of bone and joint pathology with emphasis on practical diagnostic aspects, including many illustrations: roentgenograms, CT-scans, MRI, scintigraphies, as well as pictures of gross surgical specimens and microphotographs, immunohistochemical reactions and genomics. Information on histopathological and molecular diagnosis, and basic therapeutic guidelines are provided. This boo…
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Other Authors
Santini-Araujo, Eduardo
Kalil, Ricardo K.
Bertoni, Franco
Park, Yong-Koo
Responsibility
Eduardo Santini-Araujo, Ricardo K. Kalil, Franco Bertoni, Yong-Koo Park, editors
Edition
Second edition
Alternate Title
Tumours and tumour-like lesions of bone
Place of Publication
Cham
Publisher
Springer
Date of Publication
c2020
Physical Description
1 online resource (xlviii, 1002 p.) : 1244 illus., 681 illus. in color
ISBN
9783030283155
9783030283148 (Print ed.)
9783030283162 (Print ed.)
9783030283179 (Print ed.)
Subjects (MeSH)
Bone Neoplasms
Specialty
Medical Oncology
Osteology
Abstract
This updated second edition of a successful book provides essential, internationally applicable information in the area of bone and joint pathology with emphasis on practical diagnostic aspects, including many illustrations: roentgenograms, CT-scans, MRI, scintigraphies, as well as pictures of gross surgical specimens and microphotographs, immunohistochemical reactions and genomics. Information on histopathological and molecular diagnosis, and basic therapeutic guidelines are provided. This book offers generous coverage of epidemiology, clinical features, radiology, pathology, differential diagnosis, prognosis and treatment, not only for common lesions, but also for those less frequently encountered, including lesions of joints. The content is arranged based on the World Health Organization’s Consensus Classification, with the addition of other lesions not included therein. Tumors and Tumor-Like Lesions of Bone provides day-to-day assistance to general and specialized surgical pathologists, radiologists, orthopedic, head and neck and dental surgeons, oncologists and rheumatologists.
Contents
Part I. Introduction -- Part II. Bone-forming Tumors -- Part III. Cartilage-forming Tumors -- Part IV. Giant Cell Tumor -- Part V. Round Cell Tumors -- Part VI. Fibrous Tumors -- Part VII. Tumors of Undetermined Origin -- Part VIII. Vascular Tumors -- Part IX. Adamantinoma -- Part X. Notochordal Tumors -- Part XI. Leiomyosarcoma -- Part XII. Adipocytic Tumors -- Part XIII. Neurogenic Tumors -- Part XIV. Phosphaturic Mesenchymal Tumor -- Part XV. Metastatic Carcinoma Involving Bone -- Part XVI. Tumor-like Lesions and Other Conditions That Simulate Primary Bone Tumors -- Part XVII. Tumors and Tumor-like Lesions of Joints.
Format
e-Book
Location
Online
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Secondary Hypertension

https://libcat.nshealth.ca/en/permalink/provcat45222
Alberto Morganti, Enrico Agabiti Rosei, Franco Mantero, editors. --Cham: Springer , c2020.
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This book offers an overview of the latest advances in the epidemiological, pathophysiological, diagnostic and therapeutic aspects of secondary hypertension, provided by a group of the most highly respected European experts in this field. It is common belief that secondary forms of hypertension are rare, although in 95% of patients the cause of high blood pressure is unknown – euphemistically referred to as “essential”. There is increasing evidence from epidemiological studies that the prevalen…
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Other Authors
Morganti, Alberto
Agabiti Rosei, Enrico
Mantero, Franco
Other Authors
European Society of Hypertension
Responsibility
Alberto Morganti, Enrico Agabiti Rosei, Franco Mantero, editors
Place of Publication
Cham
Publisher
Springer
Date of Publication
c2020
Physical Description
1 online resource (x, 209 p.) : 22 illus., 9 illus. in color
Series Title
Updates in hypertension and cardiovascular protection
ISBN
9783030455620
9783030455613 (Print ed.)
9783030455637 (Print ed.)
9783030455644 (Print ed.)
ISSN
2366-4606
Subjects (MeSH)
Hypertension - physiopathology
Hypertension - therapy
Specialty
Cardiology
Abstract
This book offers an overview of the latest advances in the epidemiological, pathophysiological, diagnostic and therapeutic aspects of secondary hypertension, provided by a group of the most highly respected European experts in this field. It is common belief that secondary forms of hypertension are rare, although in 95% of patients the cause of high blood pressure is unknown – euphemistically referred to as “essential”. There is increasing evidence from epidemiological studies that the prevalence of secondary hypertension is much higher than previously thought, accounting for 20%-25% of all hypertensive patients. There are additional, very good reasons for identifying those patients with secondary hypertension: firstly, they are exposed to a greater risk of suffering major cardiovascular events than patients with essential hypertension who have the same blood pressure level, and for this reason require particular care. Secondly, these patients can be relieved of a lifetime of pharmacological therapy or, at least, have a chance to be treated with more specific and effective medications. A high degree of clinical skill is required to recognize the often vague and subtle symptoms and signs that characterize patients with secondary hypertension, and clinicians need to fully comprehend the mechanisms responsible for the development and maintenance of high blood pressure. Shedding new light on a complex area of cardiovascular medicine, the book enables readers to better treat affected patients.
Contents
Renal Parenchymal Disease -- Atherosclerotic Renovascular Disease -- Fibromuscular Dysplasia: From a Rare Cause of Renovascular Hypertension to a More Frequent Systemic Arterial Disease -- Primary Aldosteronism -- Familial Hyperaldosteronism -- Monogenic Forms of Hypertension -- Pheochromocytoma and Paraganglioma -- Hypertension in Cushing’s Syndrome -- Vascular Disease -- Obstructive Sleep Apnea -- Drug-Induced Hypertension -- Hypertension in Acromegaly -- Organ Damage - Secondary Hypertension and Cardiovascular Risk: An Overview.
Format
e-Book
Location
Online
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Psychosexual Counseling in Andrological Surgery : A Multidisciplinary Approach to the Patient and His Family

https://libcat.nshealth.ca/en/permalink/provcat44330
Elena Vittoria Longhi, Giorgio Franco, Fulvio Colombo. --Cham: Springer , 2019.
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This book combines concise descriptions of the various andrological surgical interventions in the adolescent and adult with detailed analysis of the pre- and postoperative psychosexual counseling of the patient and his family that is appropriate to each procedure. It offers a multidisciplinary approach to the candidate for andrological surgery that reflects the everyday experiences of an andro-sexology team. Each chapter focuses on a particular surgical procedure. Succinct description of the di…
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Author
Longhi, Elena Vittoria
Other Authors
Franco, Giorgio
Colombo, Fulvio
Responsibility
Elena Vittoria Longhi, Giorgio Franco, Fulvio Colombo
Place of Publication
Cham
Publisher
Springer
Date of Publication
2019
Physical Description
1 online resource (xxv, 242 p.) : 16 illus., 14 illus. in color
ISBN
9783319996462
9783319996448 (Print ed.)
9783319996455 (Print ed.)
Subjects (MeSH)
Adolescent
Adult
Andrology
Body Image
Counseling
Family Relations
Genital Diseases, Male - surgery
Genitalia, Male - surgery
Sexuality - psychology
Specialty
Men's Health
Sexual Health
Abstract
This book combines concise descriptions of the various andrological surgical interventions in the adolescent and adult with detailed analysis of the pre- and postoperative psychosexual counseling of the patient and his family that is appropriate to each procedure. It offers a multidisciplinary approach to the candidate for andrological surgery that reflects the everyday experiences of an andro-sexology team. Each chapter focuses on a particular surgical procedure. Succinct description of the disease and its epidemiology, diagnosis, and treatment is followed by extensive discussion of all aspects of psychosexual relevance and the required counseling. Topics addressed include, for example, the impact of diagnosis, body image issues, fears relating to the surgical procedure and its outcome, the risk of excessive expectations and consequent disillusionment, relationship issues and communication problems, and the role of the sexologist. The analysis and guidance offered in this book will be of particular value to the less experienced andrologist and will assist in achieving postoperative patient satisfaction.
Contents
Part I. Basic Considerations -- 1. Who Is the Surgical Patient? -- 2. Illness and Individual Reactions -- 3. The Teenager and His Parents: How Do They Face Andrological Surgery? -- 4. LGBT Families -- 5. Body Image: What Does It Tell the Andrologist Surgeon? -- 6. Identity Card: Body Image Diagnosis -- 7. Body Image, Homosexuality, and Emotional Brain -- 8. The Doctor-Patient Relationship Referral to the Sexologist and How to Be Understood by Patients -- 9. Sexological Anamnesis: How to Discover the Reasons for HIS and HER Intimacy -- 10. Role of Informed Consent in Andrological Surgery in Adolescents and Adults -- Part II. The Teenager and His Parents -- 11. Sexological Aspects Associated with Delayed Puberty and “Small Penis Syndrome” -- 12. Surgical Correction of Symptomatic Varicocele in Adolescents -- 13. Monorchidism, Anorchidism, and Testicular Prosthesis in Children and Adolescents -- 14. Sperm Retrieval in the Azoospermic Patient in Young Adult and Humans: The Klinefelter Syndrome -- Part III. The Patient and the Partner -- 15. Penile Prosthesis Implant in Neurological Patients -- 16. Penectomy for Penile Malignancy Quality of Life and Sexual Disorders -- 17. Orchiectomy for Testicular Malignancy Sexual Disorders and Quality of Life -- 18. Surgical and Radiological Correction of Varicocele in Infertile Male: Sexuality and Quality of Life -- 19. Penile Prosthesis Implant Following Pelvic Surgery -- 20. Penile Prosthesis Implant for Severe Erectile Dysfunction -- 21. A Clinical Experience: Two-Year Experience with Post-surgical Sexual Rehabilitation in Alto Adige.
Format
e-Book
Location
Online
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The Mediastinal Mass : A Multidisciplinary Approach

https://libcat.nshealth.ca/en/permalink/provcat42628
Renato Franco, Federica Zito Marino, Antonio Giordano, editors. --Cham: Humana Press , c2018.
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This book discusses the main approaches for mediastinal mass diagnosis and treatment, whose different aspects have been thoroughly treated by a multidisciplinary team of experts from different clinical fields. The complex anatomy of the mediastinum, as well as the different clinical, radiographic and prognostic features of mediastinal tumors suggests that specialists adopt more flexible and comprehensive practices, as highlighted in this text. The book includes a brief introductory section desc…
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Other Authors
Franco, Renato
Zito Marino, Federica
Giordano, Antonio
Responsibility
Renato Franco, Federica Zito Marino, Antonio Giordano, editors
Place of Publication
Cham
Publisher
Humana Press
Date of Publication
c2018
Physical Description
1 online resource (xii, 309 p.) : 97 illus., 78 illus. in color
Series Title
Current clinical pathology
ISBN
9783319903682
9783319903675 (print ed.)
9783319903699 (print ed.)
ISSN
2197-781X
Subjects (MeSH)
Mediastinal Neoplasms
Specialty
Medical Oncology
Abstract
This book discusses the main approaches for mediastinal mass diagnosis and treatment, whose different aspects have been thoroughly treated by a multidisciplinary team of experts from different clinical fields. The complex anatomy of the mediastinum, as well as the different clinical, radiographic and prognostic features of mediastinal tumors suggests that specialists adopt more flexible and comprehensive practices, as highlighted in this text. The book includes a brief introductory section describing the anatomic sites of mediastinal masses and the epidemiological evidence for each different clinical-pathological entity. In particular, specific chapters are dedicated to thymic tumors, lymphomas, thyroid and parathyroid masses, and germ cell tumors of the anterior mediastinum. The Mediastinal Mass: A Multidisciplinary Approach provides a valuable resource for clinicians, surgeons, radiologists and pathologists dealing with the management and treatment of mediastinal masses through a multidisciplinary approach.
Contents
Introduction: Epidemiology, Mediastinal Anatomy, Mediastinal Masses -- Clinical Approach: Recommendations for the Clinicians -- Mediastinal Masses: Radiological Point of View -- Radiotherapy in Anterior Mediastinum Cancers -- Surgery: Reccomandations for Surgeons -- Diagnostic Histopathology Approach -- Thymic Tumors and Lymphomas: The Clinical Impact of their Underlying Molecular Features -- Therapy: Recommendations for the Oncologists -- Thymic Neoplasm -- Primitive Mediastinal Germ Cell Tumors: An Update -- Thyroid -- Parathyroid -- Mediastinal Lymphoma -- Granulomatous Disease -- Cysts of The Middle Mediastinum -- Tracheal Tumors -- Nerve Sheath Tumors, Ganglion Tumours and Neurenteric Cysts -- Esophageal Tumors.
Format
e-Book
Location
Online
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Uterine Cancer : Screening, Diagnosis, and Treatment

https://libcat.nshealth.ca/en/permalink/provcat42687
Franco Muggia, Alessandro D. Santin, Esther Oliva, editors. (Second Edition) --Cham: Springer , c2018.
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There are more than 63,000 new cases of uterine and endometrial cancer each year in the United States, up from approximately 41,000 when the first edition of Uterine Cancer was published in 2009. A book focusing on these cancers was timely, with emergent sophistication in diagnosis increasingly impacting clinical decision-making. However, five years later, the need for an updated book on this topic is even stronger as oncologists recognize opportunities to impact the outcome on women that are i…
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Other Authors
Muggia, Franco
Santin, Alessandro D.
Oliva, Esther
Responsibility
Franco Muggia, Alessandro D. Santin, Esther Oliva, editors
Edition
Second Edition
Place of Publication
Cham
Publisher
Springer
Date of Publication
c2018
Physical Description
1 online resource (xii, 278 p.) : 70 illus
Series Title
Current clinical oncology
ISBN
9783319472690
9783319472676 (print ed.)
9783319472683 (print ed.)
9783030095864 (print ed.)
ISSN
2364-1134
Subjects (MeSH)
Uterine Neoplasms
Specialty
Gynecology
Medical Oncology
Abstract
There are more than 63,000 new cases of uterine and endometrial cancer each year in the United States, up from approximately 41,000 when the first edition of Uterine Cancer was published in 2009. A book focusing on these cancers was timely, with emergent sophistication in diagnosis increasingly impacting clinical decision-making. However, five years later, the need for an updated book on this topic is even stronger as oncologists recognize opportunities to impact the outcome on women that are increasingly diagnosed with these malignancies. Uterine Cancer: Screening, Diagnosis, and Treatment, Second Edition, part of the Current Clinical Oncology series, enhances the awareness on this somewhat neglected area of therapeutics, helping to integrate targeted therapies into the management of women with uterine cancer. Written by experts in the field in a highly practical and comprehensive manner, it is a must-have for all gynecological residents and fellows, as well as gynecological oncologists, medical oncologists, radiation oncologists, and family practice doctors who wish to provide their patients with the best possible care.
Contents
The Essential Epidemiology of Cancer of the Endometrium -- Endometrial Cancer: Screening, Diagnosis, and Surgical Staging -- Imaging in the Diagnosis and Treatment of Endometrial Cancer -- Uterine Cancer: Pathology -- Molecular Pathology and Cytogenetics of Endometrial Carcinoma, Carcinosarcoma, and Uterine Sarcomas -- Prognostic Factors in Uterine Cancer -- Primary Hormonal Therapy of Endometrial Cancer -- Early-Stage Endometrial Cancer: Surgery -- Early-Stage Endometrial Cancer: Radiation'Less May Be More -- Therapeutic Modalities in Early-Stage Uterine Papillary Serous Carcinomas, Carcinosarcomas, Clear-Cell and Mixed Histology Carcinomas: Treatment of Choice Is Combined Chemotherapy and Radiation -- Treatment of Advanced and Recurrent Carcinoma: Chemotherapy -- Treatment for Advanced and Recurrent Carcinoma: Combined Modalities -- Management of Uterine Sarcomas -- Future Directions and New Targets in Endometrial Cancer.
Format
e-Book
Location
Online
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Temporal Bone Cancer

https://libcat.nshealth.ca/en/permalink/provcat42912
edited by Paul W. Gidley, Franco DeMonte. --Cham, Switzerland: Springer , c2018.
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This volume comprehensively reviews the current literature on temporal bone cancer and the multidisciplinary approaches used to managing these rare tumors. The text will review important medical issues as they specifically relate to temporal bone cancer such as advanced imaging, pathologic classification, skull base surgery, plastic reconstructive surgery, and advances in osseointegrated implants for hearing restoration. Additional chapters are dedicated to the evaluation and management, diagno…
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Other Authors
Gidley, Paul W.
DeMonte, Franco
Responsibility
edited by Paul W. Gidley, Franco DeMonte
Place of Publication
Cham, Switzerland
Publisher
Springer
Date of Publication
c2018
Physical Description
1 online resource (xii, 431 p.) : 313 illus., 225 illus. in color
ISBN
9783319745398
9783319745381 (print ed.)
9783319745404 (print ed.)
Subjects (MeSH)
Skull Neoplasms
Temporal Bone
Specialty
Medical Oncology
Otolaryngology
Abstract
This volume comprehensively reviews the current literature on temporal bone cancer and the multidisciplinary approaches used to managing these rare tumors. The text will review important medical issues as they specifically relate to temporal bone cancer such as advanced imaging, pathologic classification, skull base surgery, plastic reconstructive surgery, and advances in osseointegrated implants for hearing restoration. Additional chapters are dedicated to the evaluation and management, diagnostic radiology, surgical planning and techniques, radiotherapy, chemotherapy, and rehabilitation. An emphasis is placed on the multidisciplinary approach required for the optimal care of these rare tumors. Written by leaders in the field, Temporal Bone Cancer will be an invaluable resource for residents and fellows in Otolaryngology, Neurosurgery and Neurotology, and clinicians with interest in the primary tumors of the temporal bone. .
Contents
Overview and Historical Developments -- Evaluation and Staging of Temporal Bone Tumors -- Diagnostic Imaging of Temporal Bone Cancer -- Balloon Test Occlusion in Temporal Bone Tumors -- Pathology of Malignant Neoplasms of the Ear and Temporal Bone -- Auricular and Periauricular Skin Cancers -- Squamous Cell Carcinoma and Basal Cell Carcinoma of the Ear Canal and Temporal Bone -- Melanoma of the Ear Canal and Temporal Bone -- Unusual Tumors of the Ear Canal -- Unusual Tumors of the Middle Ear -- Unusual Tumors of the Temporal Bone -- Hematologic Malignancies Affecting the Temporal Bone -- Sarcomas of the Temporal Bone -- Temporal Bone Malignancies in children -- Metastatic Lesions to the Temporal Bone -- Mastoidectomy and Facial Nerve Decompression -- Lateral Temporal Bone Resection -- Subtotal and Total Temporal Bone Resection -- Jugular Foramen Approach -- Infratemporal Fossa Approach -- Middle Fossa Craniotomy -- Parotidectomy and Neck Dissection for Temporal Bone Malignancy -- Management of the Facial Nerve -- Facial Reanimation of Temporal Bone Cancer -- Reconstructive Techniques for Temporal Bone Cancer -- Management of the Eye in the Setting of Facial Nerve Paralysis -- Auditory Rehabilitation for Temporal Bone Cancer -- Auricular Prosthetic Rehabilitation -- Radiotherapy for Temporal Bone Cancers -- Radiation Effects on the Temporal Bone -- Chemotherapy for Temporal Bone Cancer -- Temporal Bone Cancers and Quality of Life.
Format
e-Book
Location
Online
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Locoregional Tumor Therapy

https://libcat.nshealth.ca/en/permalink/provcat43086
Eric Van Cutsem, Thomas J. Vogl, Franco Orsi, Alberto Sobrero, editors. (Second edition) --Cham: Springer , c2018.
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Online
This book presents, in condensed form, the clinical results achieved by means of various locoregional tumor therapies employed for different indications. In so doing, it will allow the reader to rapidly retrieve the information on indications and effectiveness that is required for optimal integration of these highly effective therapies into modern, complex treatment strategies. The renaissance in locoregional tumor therapies is an ongoing process. New chemotherapeutic schedules, especially for …
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Other Authors
Van Cutsem, Eric
Vogl, Thomas J.
Orsi, Franco
Sobrero, Alberto
Responsibility
Eric Van Cutsem, Thomas J. Vogl, Franco Orsi, Alberto Sobrero, editors
Edition
Second edition
Place of Publication
Cham
Publisher
Springer
Date of Publication
c2018
Physical Description
1 online resource (viii, 274 p.) : 7 illus., 4 illus. in color
ISBN
9783319699479
9783319699462 (print ed.)
9783319699486 (print ed.)
Subjects (MeSH)
Ablation Techniques
Chemoembolization, Therapeutic
Neoplasms - drug therapy
Specialty
Medical Oncology
Abstract
This book presents, in condensed form, the clinical results achieved by means of various locoregional tumor therapies employed for different indications. In so doing, it will allow the reader to rapidly retrieve the information on indications and effectiveness that is required for optimal integration of these highly effective therapies into modern, complex treatment strategies. The renaissance in locoregional tumor therapies is an ongoing process. New chemotherapeutic schedules, especially for liver and lung tumors, have been developed during the past few years. Other targeted therapies, such as radioembolization, microwave ablation, and HIFU techniques, and new pharmaceuticals for intra-arterial therapy have been developed and implemented in clinical practice. Furthermore, the advantages of unlimited combination of starch microspheres with various antitumor agents, supported by effective ischemia, have been increasingly exploited. The second edition of this book reflects these advances and includes entirely new chapters on the role of intraperitoneal perfusion in treating peritoneal carcinomatosis and the use of limb perfusion. Locoregional Tumor Therapy will be invaluable for all practitioners who work with cancer patients.
Contents
Part I. Basics of Regional Tumor Therapies -- 1. Pharmacokinetic Aspects of Regional Tumor Therapy -- 2. Embolization Materials, Catheters, and Intra-Arterial Ports -- Part II. Intra-arterial Therapies: Liver -- 3. HCC -- 4. Indications for Locoregional Tumor Therapies: CRC Liver Metastases -- 5. Liver Metastases of Neuroendocrine Tumors and CCC -- 6. Liver Metastases of Other Indications -- Part III. Intra-arterial Therapies: Lung, Head and Neck - 7. Chemoperfusion and Chemoembolization of Malignant Pulmonary Tumors -- 8. Head and Neck -- Part IV. Thermoablation -- 9. Thermal Ablation for Treating Malignant Tumors to the Liver -- 10. Radiofrequency Ablation for Treating Malignant Tumors to the Lungs -- Part V. Other locoregional Tumor Therapies -- 11. Treatment of Peritoneal Carcinomatosis -- 12. Melanoma.
Format
e-Book
Location
Online
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Advanced Concepts in Lumbar Degenerative Disk Disease

https://libcat.nshealth.ca/en/permalink/provcat40361
João Luiz Pinheiro-Franco, Alexander R. Vaccaro, Edward C. Benzel, H. Michael Mayer, editors. (1st ed.) --Berlin, Heidelberg: Springer , c2016.
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In this book, leading international specialists in the field join forces to discuss topics, issues, and approaches that are of key importance in the optimal treatment of lumbar degenerative disk disease. The coverage is wide ranging, from current understanding of physiopathology and genetics and modern imaging techniques through to the diverse minimally invasive, non-fusion, and fusion surgical techniques. Detailed attention is drawn to the most important aspects to be considered when approachi…
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Other Authors
Pinheiro-Franco, João Luiz
Vaccaro, Alexander R
Benzel, Edward C
Mayer, H. Michael
Responsibility
João Luiz Pinheiro-Franco, Alexander R. Vaccaro, Edward C. Benzel, H. Michael Mayer, editors
Edition
1st ed.
Place of Publication
Berlin, Heidelberg
Publisher
Springer
Date of Publication
c2016
Physical Description
1 online resource (xxv, 833 p. : 342 illus., 183 illus. in color)
ISBN
9783662477564
9783662477557 (print ed.)
Subjects (MeSH)
Intervertebral Disc Degeneration
Intervertebral Disc - pathology
Lumbar Vertebrae
Abstract
In this book, leading international specialists in the field join forces to discuss topics, issues, and approaches that are of key importance in the optimal treatment of lumbar degenerative disk disease. The coverage is wide ranging, from current understanding of physiopathology and genetics and modern imaging techniques through to the diverse minimally invasive, non-fusion, and fusion surgical techniques. Detailed attention is drawn to the most important aspects to be considered when approaching the patient and making treatment decisions. The role of conservative management is appraised, and surgical techniques and their indications are carefully described. Emphasis is placed on the importance of sagittal balance for treatment success. Among the various other subjects covered are psychosocial issues, legal aspects, outcome evaluation, and the relative merits of evidence-based medicine and individual experience. In the concluding section, some of the top specialists from across the world reflect on the lessons that they have learned during lifetimes in spinal surgery. Advanced Concepts in Lumbar Degenerative Disk Disease is intended as the definitive book on this important subject. It will be an instructive and fascinating source of information for all spine surgeons and other spine care providers.
Contents
Essentials in Lumbar Degenerative Disk Disease -- Imaging -- General Important Aspects When Treating Symptomatic Lumbar Degenerative Disk Disease -- Lumbar Disk Herniations -- Surgical Treatment of Lumbar Degenerative Disk Disease: Doubts, Decisions, and Techniques -- Minimally Invasive Techniques -- Nonfusion Technologies -- DDD and Spine Deformity and Sagittal Balance -- Lessons from a Life.
Format
e-Book
Location
Online
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Locoregional tumor therapy

https://libcat.nshealth.ca/en/permalink/provcat33613
Eric Van Cutsem, Thomas J. Vogl, Vranco Orsi, Alberto Sobrero, editors. --Berlin: Springer , c2015.
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Location
Online
Available Online
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Other Authors
Cutsem, Eric van
Vogl, Thomas J
Orsi, Franco
Sobrero, Alberto
Responsibility
Eric Van Cutsem, Thomas J. Vogl, Vranco Orsi, Alberto Sobrero, editors
Place of Publication
Berlin
Publisher
Springer
Date of Publication
c2015
Physical Description
1 online resource (vi, 161 pages)
ISBN
9783642365720 (electronic bk.)
9783642365713
Subjects (MeSH)
Neoplasms - drug therapy
Ablation Techniques
Subjects (LCSH)
Tumors - Treatment
Contents
1. Introduction -- Part I. Basics of Regional Tumor Therapies -- 2. Pharmacokinetic Aspects of Regional Tumor Therapy -- 3. Embolization Materials, Catheters, and Intra-arterial Ports -- Part II. Intra-arterial Therapies: Liver -- 4. HCC -- 5. CRC Liver Metastases -- 6. Liver Metastases of Neuroendocrine Tumors and CCC -- 7. Liver Metastases of Other Indications -- Part III. Intra-arterial Therapies: Lung, Head and Neck -- 8. Chemoembolization of Lung Tumors -- 9. Head and Neck -- Part IV. Thermoablation -- 10. Radiofrequency Ablation for Treating Malignant Tumors to the Liver -- 11. Radiofrequency Ablation for Treating Malignant Tumors to the Lungs.
Format
e-Book
Location
Online
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Tumors and Tumor-Like Lesions of Bone : For Surgical Pathologists, Orthopedic Surgeons and Radiologists

https://libcat.nshealth.ca/en/permalink/provcat38900
Eduardo Santini-Araujo, Ricardo K. Kalil, Franco Bertoni, Yong-Koo Park, editors. --London: Springer , c2015.
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Online
This book provides essential, internationally applicable information in the area of orthopedic pathology with emphasis on practical diagnostic aspects, including many illustrations: roentgenograms, CT-scans, MRI, scintigraphies, as well as pictures of gross surgical specimens and microphotographs, immunohistochemical reactions and genomics. Information on histopathological and molecular diagnosis, and basic therapeutic guidelines are provided. This book offers generous coverage of epidemiology,…
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Other Authors
Santini-Araujo, Eduardo
Kalil, Ricardo K
Bertoni, Franco
Park, Yong-Koo
Responsibility
Eduardo Santini-Araujo, Ricardo K. Kalil, Franco Bertoni, Yong-Koo Park, editors
Place of Publication
London
Publisher
Springer
Date of Publication
c2015
Physical Description
1 online resource (xx, 994 p. : 1005 illus., 563 illus. in color)
ISBN
9781447165781
9781447165774 (print ed.)
Subjects (MeSH)
Bone Neoplasms
Neoplasms, Connective Tissue
Abstract
This book provides essential, internationally applicable information in the area of orthopedic pathology with emphasis on practical diagnostic aspects, including many illustrations: roentgenograms, CT-scans, MRI, scintigraphies, as well as pictures of gross surgical specimens and microphotographs, immunohistochemical reactions and genomics. Information on histopathological and molecular diagnosis, and basic therapeutic guidelines are provided. This book offers generous coverage of epidemiology, clinical features, radiology, pathology, differential diagnosis and treatment, not only for common lesions, but also those less frequently encountered. Clues in the images and histopathology needed to arrive at a sharp differential diagnosis are discussed. The content is arranged based on the World Health Organization's Consensus Classification, with the addition of other lesions not included therein. Tumors and Tumor-Like Lesions of Bone is aimed at general and specialised surgical pathologists, radiologists, orthopedic surgeons, and oncologists, in practice and in training.
Contents
Introduction -- Bone-forming tumors -- Cartilage-forming tumors -- Giant cell tumor -- Round cell tumor -- Fibrous tumors -- Fibrohistiocytic tumors -- Vascular Tumors -- Adamantinoma -- Notochordal tumors -- Leiomyosarcoma -- Adipocytic tumors -- Neurogenic tumors -- Phosphaturic mesenchymal tumor -- Metastatic carcinoma involving bone -- Tumor-like lesions and other conditions that simulate primary tumors.
Format
e-Book
Location
Online
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Rare Malignant Skin Tumors

https://libcat.nshealth.ca/en/permalink/provcat38996
Franco Rongioletti, Irina Margaritescu, Bruce R Smoller. --New York, NY: Springer , c2015.
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This book provides practitioners with a single volume that reviews the clinical and pathologic features of rarely encountered cutaneous neoplasms. The text includes an in-depth discussion of the clinical findings, as well as the histologic and immunologic features of these diseases that are rarely encountered, reported, or recognized. Additional laboratory data used to make and support the diagnoses with some therapeutic and prognostic hints are discussed for each entity. The volume is organize…
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Author
Rongioletti, Franco
Other Authors
Margaritescu, Irina
Smoller, Bruce R
Responsibility
Franco Rongioletti, Irina Margaritescu, Bruce R Smoller
Place of Publication
New York, NY
Publisher
Springer
Date of Publication
c2015
Physical Description
1 online resource (xviii, 347 p. : 358 illus. in color)
ISBN
9781493920235
9781493920228 (print ed.)
Subjects (MeSH)
Rare Diseases
Skin Neoplasms
Abstract
This book provides practitioners with a single volume that reviews the clinical and pathologic features of rarely encountered cutaneous neoplasms. The text includes an in-depth discussion of the clinical findings, as well as the histologic and immunologic features of these diseases that are rarely encountered, reported, or recognized. Additional laboratory data used to make and support the diagnoses with some therapeutic and prognostic hints are discussed for each entity. The volume is organized into general categories correlating with the cell(s) of origin. An atlas of clinical manifestations is presented for each entity that will serve as a bedside clinical reference, followed by a series of photomicrographs depicting the histologic changes. In all cases, recent updates on molecular tools helpful in attaining the diagnosis are added to the sections on histology and immunohistochemistry. Rare Malignant Skin Tumors is a valuable bedside reference for the practicing dermatopathologist, general pathologist reviewing skin biopsies, general dermatologists, cutaneous oncologists and Mohs surgeons.
Contents
Adenoid (Acantholytic) Squamous Cell Carcinoma -- Clear cell and signet ring cell squamous carcinoma -- Squamous cell carcinoma with mucinous metaplasia -- Adenosquamous cell carcinoma -- Mucoepidermoid carcinoma -- Carcinosarcoma -- Lymphoepithelioma-like carcinoma -- Fibroepithelioma of Pinkus -- Basal Cell Carcinoma with Matrical Differentiation -- Trichoblastic Carcinoma -- Malignant proliferating trichilemmal tumor -- Trichilemmal carcinoma -- Pilomatrix carcinoma -- Sebaceous gland carcinoma -- Primary cutaneous apocrine adenocarcinoma -- Extramammary Paget's Disease -- Primary Cutaneous Adenoid Cystic Carcinoma -- Malignant mixed tumor of skin -- Hidradenocarcinoma -- Malignant cylindroma -- Malignant Eccrine Spiradenoma -- Microcystic adnexal carcinoma -- Syringoid Eccrine Carcinoma -- Digital papillary adenocarcinoma -- Porocarcinoma -- Signet-ring cell carcinoma of the eyelid/Histiocytoid variant of eccrine sweat gland carcinoma of the eyelid -- Primary mucinous carcinoma of the skin -- Endocrine mucin-producing sweat gland carcinoma -- Low-Grade Fibromyxoid Sarcoma -- Myxofibrosarcoma -- Fibrosarcoma -- Dermatofibrosarcoma protuberans -- Malignant fibrous histiocytoma (pleomorphic undifferentiated sarcoma) -- Epithelioid sarcoma -- Composite Hemangioendothelioma -- Epithelioid hemangioendothelioma -- Kaposiform Hemangioendothelioma -- Retiform Hemangioendothelioma -- Pseudomyogenic Hemangioendothelioma -- Spindle cell liposarcoma -- Myxoid liposarcoma -- Cutaneous Leiomyosarcoma -- Primary Cutaneous Rhabdomyosarcoma -- Malignant rhabdoid tumour -- Primary cutaneous extraskeletal osteosarcoma -- Desmoplastic melanoma -- Signet Ring Cell Melanoma -- Myxoid melanoma -- Rhabdoid melanoma -- Balloon cell melanoma -- Minimal Deviation Melanoma/Nevoid Melanoma -- Spitzoid melanoma -- Nested melanoma of the elderly -- Malignant blue nevus -- Clear cell sarcoma of soft tissue (Malignant melanoma of soft tissue) -- Merkel cell carcinoma -- Primary cutaneous Ewing sarcoma/primitive neuroectodermal tumor -- Malignant Peripheral Nerve Sheath Tumor -- Rare Variants of Mycosis Fungoides: Folliculotropic Mycosis -- Rare Variants of Mycosis Fungoides: Granulomatous slack skin variant of mycosis fungoides -- Rare Variants of Mycosis Fungoides: Localized pagetoid reticulosis (Woringer-Kolopp type) -- Rare Variants of Mycosis Fungoides: Syringotropic mycosis fungoides -- Adult T-cell lymphoma/leukemia -- Subcutaneous panniculitis-like T-cell lymphoma -- Extranodal NK/T-cell lymphoma, nasal type -- Primary cutaneous CD8+ aggressive epidermotropic cytotoxic T-cell lymphoma -- Primary cutaneous /þ T-cell lymphoma -- Diffuse large B-cell lymphoma, leg type -- Intravascular lymphoma -- Blastic plasmacytoid dendritic cell neoplasm -- Cutaneous Metastases of Breast Carcinoma -- Cutaneous metastases of the gastrointestinal tract -- Cutaneous metastases of lung cancer -- Cutaneous metastases of the kidney and urogenital system -- Miscellaneous Skin Metastases.
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e-Book
Location
Online
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Stem cells in aesthetic procedures : art, science, and clinical techniques

https://libcat.nshealth.ca/en/permalink/provcat34043
Melvin A. Shiffman, Alberto Di Giuseppe, Franco Bassetto, editors. --Heidelberg: Springer , c2014.
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Interest in the use of stem cells in aesthetic procedures has been increasing rapidly, reflecting the widespread acknowledgment of the tremendous potential of stem cell fat transfer. This is, however, the first book to be devoted entirely to the subject. The book opens by reviewing the history of the development of pluripotent stem cells and the results of research into the biochemistry and physiology of stem cells. Adipose tissue anatomy and survival are discussed, and the wide range of aesthe…
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Other Authors
Shiffman, Melvin A.
Di Giuseppe, Alberto
Bassetto, Franco
Responsibility
Melvin A. Shiffman, Alberto Di Giuseppe, Franco Bassetto, editors
Alternate Title
Stem cells in esthetic procedures
Place of Publication
Heidelberg
Publisher
Springer
Date of Publication
c2014
Physical Description
1 online resource (xxiii, 822 pages)
ISBN
9783642452079 (electronic bk.)
9783642452062
Subjects (MeSH)
Adipose Tissue
Cosmetic Techniques
Reconstructive Surgical Procedures
Regenerative Medicine - methods
Stem cell transplantation
Stem cells
Subjects (LCSH)
Stem cells - Therapeutic use
Surgery, Plastic
Plastic surgery
Abstract
Interest in the use of stem cells in aesthetic procedures has been increasing rapidly, reflecting the widespread acknowledgment of the tremendous potential of stem cell fat transfer. This is, however, the first book to be devoted entirely to the subject. The book opens by reviewing the history of the development of pluripotent stem cells and the results of research into the biochemistry and physiology of stem cells. Adipose tissue anatomy and survival are discussed, and the wide range of aesthetic procedures involving stem cell fat transfer are then described in detail. These procedures relate to the face, breast, buttocks, legs, hands, penis, and Poland syndrome. In addition, potential risks and complications are identified.
Format
e-Book
Location
Online
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IL-17, IL-22 and their producing cells : role in inflammation and autoimmunity

https://libcat.nshealth.ca/en/permalink/provcat32482
Valérie Quesniaux, Bernhard Ryffel, Franco Padova, editors. (2nd ed.) --Basel: Springer , c2013.
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Location
Online
The knowledge of Th17 cells and other cell populations which secrete IL-17A, and/or IL-22 has expanded tremendously since the publication of the first edition "Th17 Cells: Role in Inflammation and Autoimmune Disease" in 2008. The present volume has been completely revised with the addition of new chapters on the IL-17 receptor family and signaling, and an in-depth review of IL-22 and innate lymphoid cells. The differentiation of naive T cells into regulatory T cells and Th17 cells as well as th…
Available Online
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Other Authors
Quesniaux, Valérie
Ryffel, Bernhard
Padova, Franco
Responsibility
Valérie Quesniaux, Bernhard Ryffel, Franco Padova, editors
Edition
2nd ed.
Place of Publication
Basel
Publisher
Springer
Date of Publication
c2013
Physical Description
1 online resource (ix, 354 p. : 25 ill., 14 ill. in color)
Series Title
Progress in inflammation research
ISBN
9783034805223
Subjects (MeSH)
Immunity, Cellular - physiology
Inflammation - physiopathology
Interleukin-17 - immunology
Interleukins - immunology
Subjects (LCSH)
Oncology
Immunology
Infectious diseases
Cell receptors
Cytokines
Cytology
Abstract
The knowledge of Th17 cells and other cell populations which secrete IL-17A, and/or IL-22 has expanded tremendously since the publication of the first edition "Th17 Cells: Role in Inflammation and Autoimmune Disease" in 2008. The present volume has been completely revised with the addition of new chapters on the IL-17 receptor family and signaling, and an in-depth review of IL-22 and innate lymphoid cells. The differentiation of naive T cells into regulatory T cells and Th17 cells as well as the plasticity of Th17 cells is discussed. The role of IL-22 in cutaneous inflammation including psoriasis has been reviewed. In addition, the volume contains critical updates on autoimmunity, organ transplantation, tumor immunology and genetic mouse models for mechanistic studies. Lastly, the latest clinical progress in neutralizing antibodies to IL-17A, IL-17RA not only confirms the therapeutic promise foreseen in 2008, but also improves our knowledge of the pathogenesis of autoimmune diseases. In summary, this is a timely update and important review of the clinical and experimental aspects of IL-17, IL-22 and their producing cells.
Contents
IL-17A family, receptors, proinflammatory effects and production -- IL-22 and IL-17 overview -- IL-17R family: Structure, signal transduction and function -- Contribution of IL-22 to Th17 responses: repairing and protecting peripheral tissues -- Central role of Th-17 cells in adaptive immune responses -- Regulatory T cells vs Th17: Differentiation of Th17 versus Treg are they mutually exclusiveáOther sources of IL-17: iNKT cells -- Retinoic acid in mucosal immune regulation -- Critical role of IL-17 in experimental arthritis -- Dual role IL-17A, F and IL-22 in allergic asthma -- Inflammasome - IL-1 - IL-17 response in lung inflammation -- The role of Il-17 in exp autoimmune mycocarditis -- Th17 cells in transplantation: actors or innocent bystanders -- Is IL-17 required to control of tuberculosisáIL-17 and mucosal host defense. Role of IL-17 and IL-17 family cytokines on tumor development -- IL-17 and TH17 cells in rheumatoid arthritis and other inflammatory conditions -- Targeting Th17 Cells for therapy of multiple sclerosis -- Involvement of interleukin-17 cytokines in human asthma -- IL-17 and/or IL-22 as potential target(s) for Crohn's disease -- Role of IL-23, IL-17 and IL-22 in psoriasis -- Contribution of IL-22 to experimental skin inflammation -- Genetic mouse models to investigate IL-17 responses -- IL-17A as a therapeutic target for autoimmune diseases -- Index.
Format
e-Book
Location
Online
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Atlas of Male Genital Disorders : A Useful Aid for Clinical Diagnosis

https://libcat.nshealth.ca/en/permalink/provcat40821
Giuseppe Micali, Marco Cusini, Pompeo Donofrio, Franco Dinotta. --Milan: Springer , c2013.
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Male genital disorders represent a common issue in medical practice, especially in the dermatological setting. Correct clinical evaluation of these disorders is essential when addressing the diagnosis, which in some cases may require histopathological confirmation. Depending on the disease, early diagnosis may be not only lifesaving, but also of fundamental importance to the planning of successful treatment. This atlas introduces the most common penile diseases, along with more rarely encounter…
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Author
Micali, Giuseppe
Other Authors
Cusini, Marco
Donofrio, Pompeo
Dinotta, Franco
Responsibility
Giuseppe Micali, Marco Cusini, Pompeo Donofrio, Franco Dinotta
Place of Publication
Milan
Publisher
Springer
Date of Publication
c2013
Physical Description
1 online resource (xii, 181 p. : ill.)
ISBN
9788847027879
9788847027862 (print ed.)
Subjects (MeSH)
Genital Diseases, Male - diagnosis
Genital Diseases, Male - pathology
Genitalia, Male - pathology
Abstract
Male genital disorders represent a common issue in medical practice, especially in the dermatological setting. Correct clinical evaluation of these disorders is essential when addressing the diagnosis, which in some cases may require histopathological confirmation. Depending on the disease, early diagnosis may be not only lifesaving, but also of fundamental importance to the planning of successful treatment. This atlas introduces the most common penile diseases, along with more rarely encountered ones. It provides invaluable guidance on clinical diagnosis by highlighting prominent clinical features and presenting particular videodermatoscopy findings when these are indicative of the diagnosis. In addition, for each condition the most appropriate treatment is proposed, taking into account recent therapeutic advances of proven benefit.
Contents
Anatomy of Male Genitalia -- Infections -- Infestations -- Sexually Transmitted Diseases -- Inflammatory Disorders -- Pigmentation Disorders -- Benign Neoplastic Disorders -- Malignant Neoplastic Disorders -- Dysembrioplastic Disorders -- Miscellaneous Disorders.
Format
e-Book
Publication Type
Atlas
Location
Online
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HCV Infection and Cryoglobulinemia

https://libcat.nshealth.ca/en/permalink/provcat31215
Franco Dammacco, editor. --Milan: Springer , c2012.
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Location
Online
In 1947, Lerner and Watson showed that the cold-precipitable proteins in serum were gammaglobulins. These "cryoglobulins" were responsible for the corresponding clinical condition "cryoglobulinemia." Meltzer and Franklin, in 1966, provided an accurate description of the typical clinical symptoms associated with cryoglobulinemia. Subsequent progress in this field was rather slow until the end of the 1980s, when cryoglobulinemia was definitively shown to be an extrahepatic manifestation of hepati…
Available Online
View e-Book
Other Authors
Dammacco, Franco
Responsibility
Franco Dammacco, editor
Place of Publication
Milan
Publisher
Springer
Date of Publication
c2012
Physical Description
1 online resource (xvii, 360 p. : 64 ill., 52 ill. in color)
ISBN
9788847017054
Subjects (MeSH)
Cryoglobulinemia
Hepacivirus
Hepatitis C, Chronic
Vasculitis - pathology
Subjects (LCSH)
Infectious diseases
Hematology
Abstract
In 1947, Lerner and Watson showed that the cold-precipitable proteins in serum were gammaglobulins. These "cryoglobulins" were responsible for the corresponding clinical condition "cryoglobulinemia." Meltzer and Franklin, in 1966, provided an accurate description of the typical clinical symptoms associated with cryoglobulinemia. Subsequent progress in this field was rather slow until the end of the 1980s, when cryoglobulinemia was definitively shown to be an extrahepatic manifestation of hepatitis C virus infection. The book is unique in its detailed presentation and fundamental approach. Highly qualified authors have contributed critical articles reviewing significant developments in our understanding of and therapeutic approach to HCV infection and cryoglobulinemia. The text is accompanied by striking color images and illustrations and highly informative tables. This comprehensive review of a systemic disease with a complex etiology is a valuable source of up-to-date, expert information not only for basic scientists and specialists in several disciplines but also for general practitioners as well as graduate and post-graduate students in clinical and medical research.
Contents
[Machine generated contents note] 1. Introductory Remarks / Domenico Sansonno -- Pt. I. Hepatitis C Virus Infection and the Role of the Immune System -- 2. Natural History, Pathogenesis, and Prevention of HCV Infection / Charles M. Rice -- 3. Immune Control of HCV Infection / Lynn B. Dustin -- 4. B Cell Activation: General to HCV-Specific Considerations / Claudia Brunetti -- 5. Organ-Specific Autoimmunity in HCV-Positive Patients / Fabio Presotto -- Pt. II. Cellular Compartments of HCV Infection (and Replication) -- 6. HCV and Blood Cells: How Can We Distinguish Infection from Association? / Charles M. Rice -- 7. Mechanisms of Cell Entry of Hepatitis C Virus / Vito Racanelli -- 8. HCV Infection of Hematopoietic and Immune Cell Subsets / Tomasz I. Michalak -- Pt. III. Cryoglobulinemia and the Complement System -- 9. Cryoglobulinemia and Chronic HCV Infection: An Evolving Story / Marten Trendelenburg -- 10. Complement System in Cryoglobulinemia / Marten Trendelenburg -- 11. Pivotal Role of C1qR in Mixed Cryoglobulinemia / Franco Dammacco -- Pt. IV. Structural and Genetic Features, Cytokines and Chemokines in Cryoglobulinemia -- 12. Mixed Cryoglobulinemia (MC) Cross-Reactive Idiotypes (CRI): Structural and Clinical Significance / Peter D. Gorevic -- 13. Molecular Insights into the Disease Mechanisms of Type II Mixed Cryoglobulinemia / Marica Garziera -- 14. Role of VCAM-1 in the Pathogenesis of Hepatitis-C-Associated Mixed Cryoglobulinemia Vasculitis / Gilles Kaplanski -- 15. Up-Regulation of B-Lymphocyte Stimulator (BLyS) in Patients with Mixed Cryoglobulinemia / Salvatore De Vita -- 16. Role of B-Cell-Attracting Chemokine-1 in HCV-Related Cryoglobulinemic Vasculitis / Franco Dammacco -- 17. Serum a-Chemokine CXCL10 and ß-Chemokine CCL2 Levels in HCV-Positive Cryoglobulinemia / Poupak Fallahi -- Pt. V. Clinical Manifestations of Cryoglobulinemia -- 18. Experimental Models of Mixed Cryoglobulinemia / Kelly L. Hudkins -- 19. Expanding Spectrum of Clinical Features in HCV-Related Mixed Cryoglobulinemia / Anna Linda Zignego -- 20. Classification of Cryoglobulinemic Vasculitis / Luca Quartuccio -- 21. Demographic and Survival Studies of Cryoglobulinemic Patients / Laura Castelnovo -- 22. HCV-Associated Membranoproliferative Glomerulonephritis / John Prentiss Johnson -- 23. Rheumatologic Symptoms in Patients with Mixed Cryoglobulinemia / Elisa Gremese -- 24. Endocrine Manifestations of HCV-Positive Cryoglobulinemia / Poupak Fallahi -- 25. Cutaneous Cryoglobulinemic Vasculitis / J. Andrew Carlson -- 26. Peripheral Neuropathy and Central Nervous System Involvement in Cryoglobulinemia / Sergio Ferrari -- 27. Long-Term Course of Patients with Mixed Cryoglobulinemia / Patrice P. Cacoub -- 28. HBV/HCV Co-infection and Mixed Cryoglobulinemia / Salvatore Sollima -- 29. Clinical and Immunological Features of HCV/HIV Co-infected Patients with Mixed Cryoglobulinemia / Patrice P. Cacoub -- 30. HCV-Negative Mixed Cryoglobulinemia: Facts and Fancies / Giuseppe Monti -- 31. Cryoglobulinemia in HCV-Positive Renal Transplant and Liver Transplant Patients / Nassim Kamar -- Pt. VI. HCV Infection, Cryoglobulinemia and Non-Hodgkin’s Lymphomas -- 32. Chromosome Abnormalities in HCV-Related Lymphoproliferation / Caterina Matteucci -- 33. Molecular Features of Lymphoproliferation in Mixed Cryoglobulinemia / Maria Paola Simula -- 34. Higher Prevalence of B-Cell Non-Hodgkin’s Lymphoma in HCV-Positive Patients with and Without Cryoglobulinemia / Domenico Sansonno -- 35. Incidence and Characteristics of Non-Hodgkin’s Lymphomas in HCV-Positive Patients with Mixed Cryoglobulinemia / Pietro Enrico Pioltelli -- 36. Waldenstrom’s Macroglobulinemia Associated with Cryoglobulinemia: Pathogenetic, Clinical, and Therapeutic Aspects / Efstathios Kastritis -- Pt. VII. Therapy of Cryoglobulinemia -- 37. Should HCV-Positive Asymptomatic Patients with Mixed Cryoglobulinemia Be Treated with Combined Antiviral Therapy? / Fernando Pons Renedo -- 38. Role of Rituximab in the Therapy of Mixed Cryoglobulinemia / Renato Fanin -- 39. Rituximab in Cryoglobulinemic Vasculitis: First- or Second-Line Therapy? / Paul Klenerman -- 40. PIRR Therapy in HCV-Related Mixed Cryoglobulinemia / Domenico Sansonno -- 41. Antiviral Therapy in HCV-Positive Non-Hodgkin’s Lymphoma: Pathogenetic Implications / Domenico Sansonno -- 42. Active or Indolent Cutaneous Ulcers in Cryoglobulinemia: How Should They Be Treated? / Maurizio Pietrogrande -- 43. Double Filtration Plasmapheresis: An Effective Treatment of Cryoglobulinemia / Paola Brescia -- 44. Emergency in Cryoglobulinemia: Clinical and Therapeutic Approach / Giuseppe Monti -- 45. Novel Therapeutic Approaches to Cryoglobulinemia: Imatinib, Infliximab, Bortezomib, and Beyond / Maurizio Zangari.
Format
e-Book
Location
Online
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Surgery in the multimodal management of gastric cancer

https://libcat.nshealth.ca/en/permalink/provcat31226
Giovanni Manzoni, Franco Roviello, Walter Siquini, editors ; foreword by Keiichi Maruyama. --Milan: Springer , c2012.
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Although there has been a slow but steady decrease in incidence, gastric cancer remains the second leading cause of cancer death worldwide. Several aspects of the oncological and surgical management are still controversial and so gastric cancer represents a challenge for the surgeon. This book aims to delineate the state of the art in the surgical and oncological treatment of gastric cancer, describing the new TNM staging system, the extent of visceral resection and lymphadenectomy focusing on …
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Other Authors
Manzoni, Giovanni
Roviello, Franco
Siquini, Walter
Responsibility
Giovanni Manzoni, Franco Roviello, Walter Siquini, editors ; foreword by Keiichi Maruyama
Place of Publication
Milan
Publisher
Springer
Date of Publication
c2012
Physical Description
1 online resource (300 p. : 100 ill. in color)
ISBN
9788847023185
Subjects (MeSH)
Combined Modality Therapy - methods
Digestive System Surgical Procedures - methods
Stomach Neoplasms
Subjects (LCSH)
Gastroenterology
Oncology
Cancer - Surgery
Surgery
Abdomen - Surgery
Abstract
Although there has been a slow but steady decrease in incidence, gastric cancer remains the second leading cause of cancer death worldwide. Several aspects of the oncological and surgical management are still controversial and so gastric cancer represents a challenge for the surgeon. This book aims to delineate the state of the art in the surgical and oncological treatment of gastric cancer, describing the new TNM staging system, the extent of visceral resection and lymphadenectomy focusing on the different open and minimally invasive surgical techniques and discussing intraoperative chemohyperthermia and neoadjuvant and adjuvant treatment. Operative endoscopy and endoscopic ultrasonography are also discussed, as these now have an important role in both diagnostic work-up and palliative care of gastric cancer patients. Only a multidisciplinary approach involving the surgeon, gastroenterologist, and oncologist can produce the comprehensive and integrated overview that today constitutes a winning strategy for the optimization of results.What we hope we have achieved is a flexible, up-to-date, exhaustive publication, rich in illustrations and consistent with evidence-based medicine.
Contents
Title page -- Copyright page -- Foreword -- Preface -- Table of contents -- Contributors -- 1. Epidemiology of Gastric Cancer and Screening Programs -- 1.1. Incidence of Gastric Cancer and Related Mortality -- 1.2. Temporal Trends in Gastric Cancer Incidence and Related Mortality -- 1.3. Epidemiology of Gastric Cancer as a Function of Site and Histology -- 1.4. Survival in Gastric Cancer Patients -- 1.5. Primary and Secondary Prevention of Gastric Cancer -- 1.5.1 Primary Prevention -- 1.5.2. Secondary Prevention -- References -- 2. Etiopathogenesis of Gastric Cancer -- 2.1 Introduction -- 2.2. Tobacco Consumption and Dietary Habits 2.3. Helicobacter pylori Infection2.4 E-Cadherin Gene (CDH1) and Diffuse Gastric Cancer -- 2.5. Microsatellite Instability and Oncogenic Mutations -- 2.6. Conclusions -- References -- 3. Lymphatic Spread, Lymph Node Stations, and Levels of Lymphatic Dissection in Gastric Cancer -- 3.1. Lymphatic Systems of the Stomach -- 3.1.1. The Anatomy and Regional Lymph Nodes of the Stomach -- 3.1.2. Physiological Lymphatic Drainage from the Stomach -- 3.2 Patterns of Lymph Node Spread in Gastric Cancer -- 3.2.1. Lymphatic Spread in Adenocarcinoma of the Upper Third of the Stomach 3.2.2 .Lymphatic Spread in Adenocarcinoma of the Middle Third of the Stomach -- 3.2.3. Lymphatic Spread in Adenocarcinoma of the Lower Third of the Stomach -- 3.2.1. Skip Metastasis -- 3.3. Levels of Lymphatic Dissection -- References -- 4. Pathologic Classifications and Staging Systems -- 4.1. Morphology -- 4.1.1. Advanced Gastric Cancer -- 4.1.1.1. Macroscopic Aspects -- 4.1.1.2 Histological Types -- 4.1.1.3. Carneiro Classification -- 4.1.2. Early Gastric Cancer -- 4.1.2.1. Macroscopic Aspects -- 4.1.2.2. Histological Types -- 4.1.2.3. Histochemical and Immunohistochemical Aspects -- 4.2. Cytochemical,Genetic, and Molecular Alterations -- 4.3. Other Microscopic Types of Carcinoma -- 4.4. The American Joint Committee on Cancer (AJCC)/International Union Against Cancer (UICC) TNM Staging System -- 4.4.1 Primary Tumor (T) -- 4.4.2. Regional Lymph Nodes (N) -- 4.4.3 Distant Metastasis (M) -- References -- 5. Prognostic Factors and Score Systems in Gastric Cancer -- 5.1. Introduction -- 5.2 .Tumor-related Prognostic Factors -- 5.3. Patient-related Prognostic Factors -- 5.4. Treatment-related Prognostic Factors -- 5.5. Prognostic Scores -- 5.6. How To Easily Calculate The GIRCG Prognostic Score -- References -- 6. Preoperative Work-up: Endoscopy and Endoscopic Ultrasonography -- 6.1. Introduction -- 6.2. Diagnosis -- 6.3. Staging -- 6.4. Endoscopic Treatment of Early Gastric Cancer -- 6.4.1. Endoscopic Mucosal Resection -- 6.4.2. Endoscopic Submucosal Dissection -- 6.4.3. Long-term Results -- 6.5. Conclusions -- References -- 7. Preoperative Work-up and Assessment of Resectability -- 7.1 Introduction -- 7.2. Endoscopic Ultrasound -- 7.3. Computed Tomography -- 7.4. Fluorodeoxyglucose Positron Emission Tomography -- 7.5. Magnetic Resonance Imaging -- 7.6. Laparoscopy -- References -- 8. Resection Margins in Gastric Cancer -- 8.1. Background -- 8.2. Treatment Options
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e-Book
Location
Online
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Clinical and Pathological Aspects of Skin Diseases in Endocrine, Metabolic, Nutritional and Deposition Disease

https://libcat.nshealth.ca/en/permalink/provcat29496
edited by Bruce R. Smoller, Franco Rongioletti. --New York, NY: Springer , c2010.
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Location
Online
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Author
Smoller, Bruce R
Other Authors
Rongioletti, Franco
Responsibility
edited by Bruce R. Smoller, Franco Rongioletti
Place of Publication
New York, NY
Publisher
Springer
Date of Publication
c2010
ISBN
9781607611813
Subjects (MeSH)
Endocrine System Diseases - complications
Metabolic Diseases - complications
Nutrition Disorders - complications
Skin Diseases - complications
Skin Diseases - pathology
Subjects (LCSH)
Dermatology
Endocrinology 
Metabolic diseases
Nutrition
Format
e-Book
Location
Online
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Uterine Cancer : Screening, Diagnosis, and Treatment

https://libcat.nshealth.ca/en/permalink/provcat29831
edited by Esther Oliva, Franco Muggia. --Totowa, NJ: Humana Press , c2009.
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Location
Online
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Author
Oliva, Esther
Other Authors
Muggia, Franco
Responsibility
edited by Esther Oliva, Franco Muggia
Place of Publication
Totowa, NJ
Publisher
Humana Press
Date of Publication
c2009
Series Title
Current clinical oncology
ISBN
9781603270441
Subjects (MeSH)
Uterine Neoplasms - diagnosis
Uterine Neoplasms - therapy
Format
e-Book
Location
Online
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Th 17 Cells : Role in Inflammation and Autoimmune Disease

https://libcat.nshealth.ca/en/permalink/provcat40954
Valérie Quesniaux, Bernhard Ryffel, Franco Di Padova, editors. --Basel: Birkhäuser Verlag , c2009.
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Location
Online
With the recent definition of the Th17 cell subset, a new paradigm in innate and adaptive immunity has been established. This book describes the function of the Th17 cell subset and its prevalent role in many inflammatory and autoimmune diseases. The mechanism by which this T cell subset is generated and maintained shows specific differences between mice and man which are reviewed. One characteristic of Th17 cells is to secrete specific and unique cytokines such as IL-17A, IL-17F and IL-22; the…
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View e-Book
Other Authors
Quesniaux, Valérie
Ryffel, Bernhard
Padova, Franco Di
Responsibility
Valérie Quesniaux, Bernhard Ryffel, Franco Di Padova, editors
Place of Publication
Basel
Publisher
Birkhäuser Verlag
Date of Publication
c2009
Physical Description
1 online resource (xii, 244 p. : 20 illus.)
Series Title
Progress in inflammation research
ISBN
9783764386818
9783764386801 (print ed.)
Subjects (MeSH)
Antibodies, Neutralizing
Autoimmune Diseases - etiology
Inflammation - etiology
Th17 Cells - immunology
Abstract
With the recent definition of the Th17 cell subset, a new paradigm in innate and adaptive immunity has been established. This book describes the function of the Th17 cell subset and its prevalent role in many inflammatory and autoimmune diseases. The mechanism by which this T cell subset is generated and maintained shows specific differences between mice and man which are reviewed. One characteristic of Th17 cells is to secrete specific and unique cytokines such as IL-17A, IL-17F and IL-22; their functions are described in detail. These cytokines have acquired a prevalent role in many pathological conditions in animal models and in humans. Targeting these cytokines as well as the generation of Th17 cells may open new ways to treat many autoimmune diseases. The role of Th17 in infectious conditions is also addressed.
Contents
Discovery and IL-17 family -- IL-22 and IL-17: Common and different properties -- Other sources of IL-17: Invariant natural killer T cells -- Contributions of IL-22 to Th17 responses: Repairing and protecting peripheral tissues -- Retinoic acid in mucosal immune-regulation -- IL-25, another promoter of allergy -- Experimental models of disease -- Critical role of IL-17 in experimental arthritis -- Dual role of IL-17 in allergic asthma -- Contribution of IL-17 to the pulmonary inflammatory response -- The role of IL-17 in experimental autoimmune myocarditis -- Th17 cells in organ transplantation -- Role of IL-23/IL-17 in infection and tumor control -- Is IL-17 required to control tuberculosis? -- IL-17 and mucosal host defense -- IL-23 orchestrates the switch from tumor immune surveillance to tumor-promoting inflammation -- IL-17 in clinical autoimmune disease -- IL-17 and Th17 cells in rheumatoid arthritis -- Targeting Th17 cells in CNS immune pathology -- IL-17 cytokines in asthma -- IL-17/23, potential targets for Crohn's disease -- Novel tools and therapeutic avenues -- IL-17A and Th17 cells as therapeutic targets for autoimmune diseases.
Format
e-Book
Location
Online
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