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Role of Folliculo-luteal Function in Human Reproduction

https://libcat.nshealth.ca/en/permalink/provcat40277
György Siklósi. --Cham: Springer , c2016.
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This book is the first to explain fully the crucial role of folliculo-luteal function in recurrent miscarriage, unexplained infertility, preterm birth, intrauterine growth retardation, preeclampsia, random chromosomal abnormalities, and age-related reproductive disorders. In addition it describes treatments to avoid these conditions and proposes a novel method, "hormonal wedge resection", that can successfully cure infertility associated with polycystic ovary syndrome. Importantly, the conclusi…
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Author
Siklósi, György
Responsibility
György Siklósi
Place of Publication
Cham
Publisher
Springer
Date of Publication
c2016
Physical Description
1 online resource (xix, 200 p. : 36 illus., 35 illus. in color)
ISBN
9783319395401
9783319395395 (print ed.)
Subjects (MeSH)
Corpus Luteum - physiopathology
Ovarian Follicle - physiopathology
Pregnancy Complications - physiopathology
Reproduction - physiology
Abstract
This book is the first to explain fully the crucial role of folliculo-luteal function in recurrent miscarriage, unexplained infertility, preterm birth, intrauterine growth retardation, preeclampsia, random chromosomal abnormalities, and age-related reproductive disorders. In addition it describes treatments to avoid these conditions and proposes a novel method, "hormonal wedge resection", that can successfully cure infertility associated with polycystic ovary syndrome. Importantly, the conclusions drawn in this book are based on the therapeutic results observed in a representative patient population. The method developed by the author to quantitatively diagnose the hormonal insufficiency of ovulatory cycles (folliculo-luteal insufficiency, FLI) has made it possible to recognize the formerly unclear importance of this function in human reproduction. Folliculo-luteal function determines the conditions of placentation and thus the features of the developed placenta and the outcome of pregnancy. Different grades of FLI are associated with consequences of varying severity that can be prevented by normalization of folliculo-luteal function prior to conception. This book will be required reading for all obstetricians and gynecologists.
Contents
1. Patients and Methods -- 2. Diagnosis of Folliculo-Luteal Function -- 3. Aetiology and Pathomechanism of Folliculo-Luteal Insufficiency -- 4. Treatment of Folliculo-Luteal Insufficiency -- 5. Recurrent Miscarriage and Folliculo-Luteal Function -- 6. Unexplained Infertility and Folliculo- Luteal Function -- 7. The Role of Folliculo-Luteal Function in the Outcome of Pregnancy -- 8. Preventing Preterm Birth, Intrauterine Growth Retardation (IUGR) and Preeclampsia by the Normalisation of Placentation -- 9. The Role of Folliculo-Luteal Insufficiency in the Emergence of Random Chromosomal Abnormalities -- 10. The Role of Folliculo-Luteal Function in the Emergence of Age-Related Reproductive Disorders -- 11. “Hormonal Wedge Resection”: An Effective Treatment Method of Anovulatory Infertility Associated with Polycystic Ovary Syndrome -- 12. The Beneficial Effects of Preconceptional Normalisation of Folliculo-Luteal Function on Reproduction -- Summary.
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e-Book
Location
Online
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Micro-, Meso- and Macro-Dynamics of the Brain

https://libcat.nshealth.ca/en/permalink/provcat43937
György Buzsáki, Yves Christen, editors. --Cham: SpringerOpen , c2016.
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How does the brain orchestrate perceptions, thoughts, and actions from the activity of its neurons? Addressing these challenging issues requires methods with sufficiently high temporal and spatial resolution of neuronal activity in both local and global networks as well as theories to advance understanding how different levels of brain dynamics interact. This book brings together leading investigators who represent various aspects of brain dynamics with the goal of presenting state-of-the-art c…
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Other Authors
Buzsáki, György
Christen, Yves
Responsibility
György Buzsáki, Yves Christen, editors
Place of Publication
Cham
Publisher
SpringerOpen
Date of Publication
c2016
Physical Description
1 online resource (xiii, 172 p.) : 33 illus., 30 illus. in color
Series Title
Research and perspectives in neurosciences
ISBN
9783319288024
9783319288017 (Print ed.)
9783319288031 (Print ed.)
9783319804293 (Print ed.)
ISSN
0945-6082
Subjects (MeSH)
Brain - physiology
Neuropsychology
Psychophysiology
Specialty
Neurology
Abstract
How does the brain orchestrate perceptions, thoughts, and actions from the activity of its neurons? Addressing these challenging issues requires methods with sufficiently high temporal and spatial resolution of neuronal activity in both local and global networks as well as theories to advance understanding how different levels of brain dynamics interact. This book brings together leading investigators who represent various aspects of brain dynamics with the goal of presenting state-of-the-art current progress and address future developments. The topics cover the most fascinating facets of neuroscience from elementary computation of neurons, mesoscopic network oscillations, internally generated assembly sequences in the service of cognition, large-scale neuronal interactions within and across systems, the impact of sleep on cognition, memory and mental illness, brain controlled robots, motor-sensory integration, spatial navigation, large-scale computation and consciousness. Overall, this volume offers an integrated view of the challenges and opportunities in deciphering brain circuits in health and disease.
Contents
Hippocampal mechanisms for the segmentation of space by goals and boundaries -- Cortical evolution: introduction to the reptilian cortex -- Flow of information underlying a tactile decision in mice -- The visual brain: computing through multiscale complexity -- Grid cells and spatial maps in entorhinal cortex and hippocampus -- The striatum and decision-making based on value -- Decoding the dynamics of conscious perception: The temporal generalization method -- Sleep and synaptic down-selection -- Psyche, signals and systems -- Federating and integrating what we know about the brain at all scales: computer science meets the clinical neurosciences.
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Open access
Format
e-Book
Location
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Interstitial Prostate Brachytherapy : LDR-PDR-HDR

https://libcat.nshealth.ca/en/permalink/provcat40795
György Kovács, Peter Hoskin, editors. --Berlin, Heidelberg: Springer , c2013.
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Prostate brachytherapy has been the subject of heated debate among surgeons and the proponents of the various brachytherapy methods. This very first interdisciplinary book on the subject provides a comprehensive overview of innovations in low dose rate (LDR), high dose rate (HDR), and pulsed dose rate (PDR) interstitial brachytherapy for the management of local or locally advanced prostate cancer. In addition to detailed chapters on patient selection and the use of imaging in diagnostics, treat…
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Other Authors
Kovács György
Hoskin, Peter
Responsibility
György Kovács, Peter Hoskin, editors
Place of Publication
Berlin, Heidelberg
Publisher
Springer
Date of Publication
c2013
Physical Description
1 online resource (vi, 260 p. : ill.)
ISBN
9783642364990
9783642364983 (print ed.)
Subjects (MeSH)
Brachytherapy - methods
Dose-Response Relationship, Radiation
Prostatic Neoplasms - radiotherapy
Radiotherapy Dosage
Abstract
Prostate brachytherapy has been the subject of heated debate among surgeons and the proponents of the various brachytherapy methods. This very first interdisciplinary book on the subject provides a comprehensive overview of innovations in low dose rate (LDR), high dose rate (HDR), and pulsed dose rate (PDR) interstitial brachytherapy for the management of local or locally advanced prostate cancer. In addition to detailed chapters on patient selection and the use of imaging in diagnostics, treatment guidance, and implantation control, background chapters are included on related medical physics issues such as treatment planning and quality assurance. The results obtained with the different treatment options and the difficult task of salvage treatment are fully discussed. All chapters have been written by internationally recognized experts in their fields who for more than a decade have formed the teaching staff responsible for the successful GEC-ESTRO/EAU Prostate Brachytherapy Teaching Course. This book will be invaluable in informing residents and others of the scientific background and potential of modern prostate brachytherapy. It will also prove a useful source of up-to-date information for those who specialize in prostate brachytherapy or intend to start an interstitial brachytherapy service.
Contents
1. Introduction -- 2. Epidemiology and Prevention of Prostate Cancer -- 3. Imaging Localised Prostate Carcinoma -- 4. Patient Selection and Recommendations on Permanent Seed Implantation as Monotherapy for Localized Prostate Cancer -- 5. Patient Selection and Recommendations: HDR -- 6. Prostate Brachytherapy Implantation Treatment Techniques -- 7. HDR Technique -- 8. Pulsed-Dose Rate Brachytherapy in Prostate Cancer -- 9. Imaging for Post-implant Dosimetry -- 10. Dosimetry Planning for Permanent Seeds -- 11. HDR Planning -- 12. Postimplant Dosimetry -- 13. Dose–Response Relationship in Permanent Implant Brachytherapy for Prostate Cancer -- 14. HDR Versus LDR Seeds -- 15. Results of Permanent Prostate Brachytherapy -- 16. Results of HDR Prostate Brachytherapy Treatments -- 17. Results of PDR Treatments: The AMC PDR Experience -- 18. Incidence and Prognostic Factors for Complications After Permanent Interstitial Brachytherapy -- 19. Salvage Treatment for Recurrent Prostate Cancer Following Brachytherapy: For Whom, When and Which? -- 20. Prostate Cancer Brachytherapy: Radiation Protection Issues.
Format
e-Book
Location
Online
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The Paraoxonases : Their Role in Disease Development and Xenobiotic Metabolism

https://libcat.nshealth.ca/en/permalink/provcat40620
edited by Bharti Mackness, Mike Mackness, Michael Aviram and György Paragh. --Dordrecht: Springer , c2008.
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Research into the paraoxonase (PON) multigene family has really only blossomed in the last 10 years. Before this time only PON1 was known and research was restricted to toxicologists investigating the metabolism of organophosphate insecticides and nerve gases and a few "mad" scientists searching for "natural" substrates. Since this time two new members PON2 and PON3 have been discovered, all 3 PONs have been shown to act as antioxidants and the PON family has taken centre stage as major players…
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Other Authors
Mackness, Bharti
Mackness, Mike
Aviram, Michael
Paragh, György
Other Authors
International Conference on Paraoxonases (2nd : 2006 : Hajdúszoboszló, Hungary)
Responsibility
edited by Bharti Mackness, Mike Mackness, Michael Aviram and György Paragh
Place of Publication
Dordrecht
Publisher
Springer
Date of Publication
c2008
Physical Description
1 online resource (xv, 323 p. : ill.)
Series Vol.
v. 6
Series Title
Proteins And Cell Regulation
ISBN
9781402065613
9781402065606 (print ed.)
Subjects (MeSH)
Aryldialkylphosphatase
Abstract
Research into the paraoxonase (PON) multigene family has really only blossomed in the last 10 years. Before this time only PON1 was known and research was restricted to toxicologists investigating the metabolism of organophosphate insecticides and nerve gases and a few "mad" scientists searching for "natural" substrates. Since this time two new members PON2 and PON3 have been discovered, all 3 PONs have been shown to act as antioxidants and the PON family has taken centre stage as major players in the development of a wide variety of diseases such as cardiovascular disease, diabetes mellitus, rheumatism, Alzheimer and many more while remaining important in determining organophosphate toxicity. In September 2006 the 2nd International Conference on Paraoxonases took place in Hajdúszoboszló, Hungary, bringing together the world's foremost experts in the field. The current book is a distillation of the plenary lectures which took place at the meeting, resulting in a comprehensive up to date, state of the art review of current paraoxonase research.
Contents
Part 1. The Bert La Du Memorial Lecture -- Paraoxonases: An Historical Perspective -- Part 2. PONs and Atherosclerosis -- Glucose Inactivates Paraoxonase 1 (PON1) and Displaces it from High Density Lipoprotein (HDL) to a Free PON1 Form -- Paraoxonase-1 and Cardiovascular Disease -- Oxidative Stress & Antioxidants and PON1 in Health and Disease -- D-4F Increases Paraoxonase 1 Activity in HDL -- Paraoxonase 1 (PON1), A Junction Between the Metabolisms of Homocysteine and Lipids -- The Role of PON2 and PON3 in Atherosclerosis and Related Traits -- Paraoxonase 1 and Postprandial Lipemia -- PON1 Genotypes and Coronary Heart Disease -- Part 3. PON1 Structure -- Human Paraoxonase I: A Potential Bioscavenger of Organophosphorus Nerve Agents -- Stabilisation of Active Form of Natural Human PON1 Requires HPBP -- Part 4. PONs in Disease other than Atherosclerosis -- Paraoxonase-1 in Chronic Liver Diseases, Neurological Diseases and HIV Infection -- Age-Related Alterations in PON1 -- Part 5. PON and Toxicology -- Paraoxonase (PON1) and Organophosphate Toxicity -- Implications of Paraoxonase-1 (PON1) Activity and Polymorphisms on Biochemical and Clinical Outcomes in Workers Exposed to Pesticides -- Part 6. PON-Genetics and Regulation -- Transcriptional Regulation of the Paraoxonase Genes -- Effect of Lipid Lowering Medications on PON1 -- The Functional Consequences of Polymorphisms in the Human PON1 Gene -- Dietary Modulation of Paraoxonase-1 Activity and Concentration in Humans -- Part 7. PONs Biochemistry -- PONs' Natural Substrates: The Key for their Physiological Roles -- Paraoxonases, Quorum Sensing, And Pseudomonas Aeruginosa.
Format
e-Book
Publication Type
Congress
Location
Online
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Internal fixation of femoral neck fractures : An atlas

https://libcat.nshealth.ca/en/permalink/provcat29897
edited by Jeno Manninger, Ulrich Bosch, Péter Cserháti, Károly Fekete, György Kazár. --Vienna: Springer-Verlag , c2007.
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Author
Manninger, Jeno
Other Authors
Bosch, Ulrich
Cserháti, Péter
Fekete, Károly
Kazár, György
Responsibility
edited by Jeno Manninger, Ulrich Bosch, Péter Cserháti, Károly Fekete, György Kazár
Place of Publication
Vienna
Publisher
Springer-Verlag
Date of Publication
c2007
ISBN
9783211685853
Subjects (MeSH)
Femoral Neck Fractures - surgery
Fracture Fixation, Internal - methods
Subjects (LCSH)
Orthopedic surgery
Format
e-Book
Location
Online
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