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Acute Kidney Injury and Regenerative Medicine

https://libcat.nshealth.ca/en/permalink/provcat45511
Yoshio Terada, Takashi Wada, Kent Doi, editors. --Singapore: Springer , c2020.
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This book presents up-to-date information on the clinical-pathophysiological features of acute renal injury and discusses the KDIGO diagnostic criteria, as well as novel experimental findings, including in the area of regenerative medicine. It also highlights the clinical-pathophysiological importance of AKI in clinical settings, including differential diagnoses and management of AKI. In the past, the pathology associated with sudden renal impairment was characterized as acute renal failure (AR…
Available Online
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Other Authors
Terada, Yoshio
Wada, Takashi
Doi, Kent
Responsibility
Yoshio Terada, Takashi Wada, Kent Doi, editors
Place of Publication
Singapore
Publisher
Springer
Date of Publication
c2020
Physical Description
1 online resource (ix, 396 p.) : 39 illus., 33 illus. in color
ISBN
9789811511080
9789811511073 (Print ed.)
9789811511097 (Print ed.)
9789811511103 (Print ed.)
Subjects (MeSH)
Acute Kidney Injury - etiology
Acute Kidney Injury - therapy
Regenerative Medicine - methods
Specialty
Nephrology
Regenerative Medicine
Abstract
This book presents up-to-date information on the clinical-pathophysiological features of acute renal injury and discusses the KDIGO diagnostic criteria, as well as novel experimental findings, including in the area of regenerative medicine. It also highlights the clinical-pathophysiological importance of AKI in clinical settings, including differential diagnoses and management of AKI. In the past, the pathology associated with sudden renal impairment was characterized as acute renal failure (ARF). However, in the 2000s, the joint efforts of specialists in fields including nephrology, intensive care medicine, and cardiovascular medicine led to the introduction of a novel concept known as acute kidney injury (AKI). As medical care progressed, patients such as high-risk elderly subjects who were not deemed to be candidates for invasive therapy came to be treated in intensive care units (ICUs). As a result, kidney injury as a subset of multiple organ failure was re-considered as AKI, especially in intensive care medicine. AKI was then proposed as a novel disease concept to emphasize the importance of early diagnosis and early intervention to improve prognosis. Presenting novel features, such as the definition of AKI, risk factors and management; biomarkers, such as neutrophil gelatinase-associated lipocalin (NGAL) and L-type fatty acid-binding protein (L-FABP); long-term outcomes of AKI; as well as renal regeneration using iPS cell, manipulation of embryonic genes, and Xenotransplanted embryonic kidney, this book is of interest to all physicians and researchers in this field around the globe.
Contents
Part I. Diagnosis and Risk Factors of AKI -- 1. Acute Kidney Injury: Definition and Epidemiology -- 2. Causes of AKI (Prerenal, Intrarenal, Postrenal) -- 3. Pathophysiology of AKI -- 4. Diagnosis of AKI: Clinical Assessment, Novel Biomarkers, History, and Perspectives -- 5. Risk Factors for AKI Development in Surgery (Non-cardiac Surgery) -- 6. Risk Factors for AKI Development in Acute Decompensated Heart Failure -- 7. Contrast-Induced Acute Kidney Injury -- 8. Antibiotics- and Immunosuppressants-Related AKI -- 9. AKI in Setting of Cancer -- 10. Community- and Hospital-Acquired Acute Kidney Injury -- Part II. Complication of AKI -- 11. Complication of Homeostasis (Electrolytes and Acid-Base) -- 12. Volume Overload and Pulmonary Complications -- Part II.I Prevention and Management of AKI -- 13. Prophylaxis and Management of Acute Kidney Injury -- 14. Postrenal AKI -- 15. Acute Kidney Injury in Intensive Care Medicine -- 16. Nondialytic Supportive Management of AKI -- 17. Renal Replacement Therapy in AKI -- 18. Short-Term and Long-Term Outcomes of AKI Patients -- 19. Management of Pediatric AKI -- Part IV. Experimental Novel Findings -- 20. AKI-to-CKD Transition -- 21. Role of the Nervous System in Acute Kidney Injury -- 22. AKI and Immune System -- 23. Acute Kidney Injury and Cytokines -- Part V. AKI and Regenerative Medicine -- 24. iPS Cell and Renal Regenerative Medicine -- 25. Kidney Development and Injury: A Road to Regeneration -- 26. Xenotransplanted Embryonic Kidney.
Format
e-Book
Location
Online
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Kidney Cancer : Recent Advances in Surgical and Molecular Pathology

https://libcat.nshealth.ca/en/permalink/provcat45064
Mukul K. Divatia, Ayhan Ozcan, Charles C. Guo, Jae Y. Ro, editors. --Cham: Springer , c2020.
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This book provides a comprehensive overview of pathology of kidney tumors along with radiological features and up to date treatment strategies that enable the readers to avail this information in day to day pathology sign-out as well as interaction with clinical colleagues of different disciplines. It also serves as a referral resource for the current medical or surgical practice while preparing for examinations or maintenance of certification. Written by experts in the field, chapters contain …
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Other Authors
Divatia, Mukul K.
Ozcan, Ayhan
Guo, Charles C.
Ro, Jae Y.
Responsibility
Mukul K. Divatia, Ayhan Ozcan, Charles C. Guo, Jae Y. Ro, editors
Place of Publication
Cham
Publisher
Springer
Date of Publication
c2020
Physical Description
1 online resource (xi, 445 p.) : 192 illus., 180 illus. in color
ISBN
9783030283339
9783030283322 (Print ed.)
9783030283346 (Print ed.)
9783030283353 (Print ed.)
Subjects (MeSH)
Kidney Neoplasms - diagnosis
Kidney Neoplasms - pathology
Kidney Neoplasms - therapy
Specialty
Nephrology
Pathology
Surgical Oncology
Abstract
This book provides a comprehensive overview of pathology of kidney tumors along with radiological features and up to date treatment strategies that enable the readers to avail this information in day to day pathology sign-out as well as interaction with clinical colleagues of different disciplines. It also serves as a referral resource for the current medical or surgical practice while preparing for examinations or maintenance of certification. Written by experts in the field, chapters contain an updated review of important pathologic parameters mandated for diagnosis and reporting with emphasis on updated information regarding new developments in this interesting field. Numerous high-resolution color images aptly illustrate the various pathologic entities and their features as outlined in the text section along with tables that highlight the differential diagnoses and salient ancillary features. Kidney Cancer serves as a quick reference for all categories of readers alike, and provides up-to-date information on renal tumor pathology, radiology and management that are required in daily practice.
Contents
Part I. Clinical Aspects -- Surgical Considerations in Renal Tumors -- Renal Cell Carcinoma: The Oncologist’s Point of View -- Part II. Histopathology and Cytology -- Normal Anatomy and Histology of the Kidney: Importance for Kidney Tumors -- Benign Renal Epithelial / Epithelial and Stromal Tumors -- Major Subtypes of Renal Cell Carcinoma -- New and Emerging Subtypes of Renal Cell Carcinoma -- Renal Mass Biopsy -- Mesenchymal Kidney Tumors -- Pediatric Renal Tumors: Diagnostic Updates -- Neuroendocrine Kidney Tumors -- Hereditary Syndromes Associated with Kidney Tumors -- Lymphoid Neoplasms of the Kidney -- Tumors of the Renal Pelvis -- Non-Neoplastic Changes in Nephrectomy Specimens for Tumors -- Application of Immunohistochemistry in Diagnosis of Renal Cell Neoplasms -- Cytology of Kidney Tumors -- Part III. Diagnostic Imaging -- Diagnostic Imaging in Renal Tumors -- Part IV. Molecular Pathology -- Molecular Pathology of Kidney Tumors -- Targeted Treatment of Renal Cell Carcinoma -- Part V. Specimen Handling, Staging and Reporting -- Specimen Handling: Radical and Partial Nephrectomy Specimens -- Staging and Reporting of Renal Cell Carcinomas.
Format
e-Book
Location
Online
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Kidney Disease in the Cardiac Catheterization Laboratory : A Practical Approach

https://libcat.nshealth.ca/en/permalink/provcat45302
Janani Rangaswami, Edgar V. Lerma, Peter A. McCullough, editors. --Cham: Springer , c2020.
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Location
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This book is the first title that focuses exclusively on kidney disease and its impact in the cardiac catheterization laboratory. The increasing prevalence of vascular risk factors such as diabetes, obesity and hypertension coupled with increased longevity has resulted in a worldwide epidemic of cardiovascular and chronic kidney disease (CKD). Never has the impact of one organ system on the other been so profound, as in the current context of cardio-renal interactions. The cross talk between th…
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Other Authors
Rangaswami, Janani
Lerma, Edgar V.
McCullough, Peter A.
Responsibility
Janani Rangaswami, Edgar V. Lerma, Peter A. McCullough, editors
Place of Publication
Cham
Publisher
Springer
Date of Publication
c2020
Physical Description
1 online resource (xx, 473 p.) : 59 illus., 40 illus. in color
ISBN
9783030454142
9783030454135 (Print ed.)
9783030454159 (Print ed.)
9783030454166 (Print ed.)
Subjects (MeSH)
Cardiac Catheterization
Cardio-Renal Syndrome - prevention & control
Contrast Media - adverse effects
Endovascular Procedures
Renal Insufficiency, Chronic - complications
Specialty
Cardiology
Nephrology
Abstract
This book is the first title that focuses exclusively on kidney disease and its impact in the cardiac catheterization laboratory. The increasing prevalence of vascular risk factors such as diabetes, obesity and hypertension coupled with increased longevity has resulted in a worldwide epidemic of cardiovascular and chronic kidney disease (CKD). Never has the impact of one organ system on the other been so profound, as in the current context of cardio-renal interactions. The cross talk between the heart and kidneys is highly relevant in the field of interventional cardiology, given the increasing number of trans-catheter procedures being performed in patients with underlying kidney disease. These procedures also have a significant impact on kidney function and require thoughtful interdisciplinary planning by a cardiorenal team, to achieve optimal outcomes This book assembles the collective expertise of several international leaders in the field of interventional cardiology and nephrology to summarize this complex interface. The book is divided into seven sections to comprehensively cover the topic, including sections on best practices with reduction of contrast associated acute kidney injury, cutting edge techniques to minimize kidney risk with complex interventions, impact of transcatheter valvular procedures on kidney function and the utility of cardio-nephrology teams. Less recognized complications with high morbidity such as athero-embolic renal disease are featured prominently, to increase awareness in the interventional cardiology and nephrology communities. This book is a valuable resource for interventional and structural cardiologists, general cardiologists and nephrologists dealing with the significant overlap areas between these two specialties. It is also relevant to medical students, trainee physicians in nephrology and cardiology, advanced care practitioners and nursing personnel in both specialties . Given the major impact of kidney function on outcomes in patients undergoing cardiac procedures, this textbook serves as a focal point to integrate relevant clinical data from both specialties and help interventional cardiologists achieve optimal outcomes, especially in patients with (or at risk for) kidney disease.
Contents
Part I. Atherosclerotic Cardiovascular Disease Burden in Chronic Kidney Disease -- 1. The Burden of Coronary Artery Disease in Chronic Kidney Disease -- 2. Non-invasive Testing in the Diagnosis of Ischemic Heart Disease in CKD: Scope, Pitfalls, and Future Directions -- 3. Peripheral Arterial Disease in Chronic Kidney Disease: Disease Burden, Outcomes, and Interventional Strategies -- 4. Cardiovascular Impact of Atherosclerotic Renovascular Disease -- Part II. Therapeutic Considerations with Revascularization in Chronic Kidney Disease -- 5. Therapeutic Considerations with Revascularization in Chronic Kidney Disease: Radial Versus Femoral Arterial Access -- 6. Antiplatelet Agent Choice and Platelet Function Testing in CKD -- 7. Choice of Stents and Clinical Outcomes in Patients with Chronic Kidney Disease -- 8. Revascularization Strategies in Chronic Kidney Disease: Percutaneous Coronary Interventions Versus Coronary Artery Bypass Graft -- 9. Approach to Revascularization in the Potential Kidney Transplant Recipient -- 10. Nephrology Consultative Approach and Risk Stratification Prior to Revascularization in Chronic Kidney Disease -- Part III. Acute Kidney Injury in the Catheterization Laboratory: Part I -- 11. Contrast-Induced Acute Kidney Injury: Epidemiology, Risk Stratification, and Prognosis -- 12. Pathophysiology of Contrast Induced Acute Kidney Injury -- 13. Prevention of Contrast-Induced AKI: Summary of Volume Optimization Strategies -- 14. Operator and Intraprocedural Strategies to Reduce Contrast-Induced Acute Kidney Injury -- Part IV. Acute Kidney Injury in the Catheterization Laboratory: Part II -- 15. Effect of Acute Mechanical Circulatory Support on Kidney Function -- 16. Renal Athero-embolic Disease: An Underdiagnosed Entity in Cardiac Catheterization -- 17. Acute Kidney Injury After Transcatheter Aortic Valve Replacement -- 18. Impact of Kidney Disease on Catheter-Based Mitral Valve Interventions -- 19. Contrast-Induced Nephropathy After Peripheral Vascular Intervention -- Part V. Catheter Based Reno-Vascular Interventions -- 20. Renal Artery Stenosis: State of the Art in the Diagnosis and Management -- 21. Renal Denervation: Physiology, Scope, and Current Evidence -- 22. Forced Matched Diuresis: Role in Renal Protection in the Cardiac Catheterization Laboratory -- Part VI. Role of Hemodynamic Evaluation in the Catheterization Laboratory -- 23. Traditional and Novel Invasive Hemodynamic Indices in the Evaluation of Congestive Heart Failure in Cardiorenal Syndrome -- 24. Pulmonary Hypertension in Chronic Kidney Disease -- Part VII. Utility of the Cardio-Nephrology Collaborative in the Cardiac Catheterization Laboratory -- 25. The Economic Impact of Kidney Disease in the Cardiac Catheterization Laboratory -- 26. Biomarkers of Acute Kidney Injury and Scope of Utilization in the Cardiac Catheterization Laboratory -- 27. A Call to Action to Develop Integrated Curricula in Cardiorenal Medicine.
Format
e-Book
Location
Online
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