Acute Kidney Injury and Regenerative Medicine
https://libcat.nshealth.ca/en/permalink/provcat45511
Yoshio Terada, Takashi Wada, Kent Doi, editors.
--Singapore:
Springer
, c2020.
- Available Online
- View e-Book
- Location
- Online
This book presents up-to-date information on the clinical-pathophysiological features of acute renal injury and discusses the KDIGO diagnostic criteria, as well as novel experimental findings, including in the area of regenerative medicine. It also highlights the clinical-pathophysiological importance of AKI in clinical settings, including differential diagnoses and management of AKI. In the past, the pathology associated with sudden renal impairment was characterized as acute renal failure (AR…
- Available Online
- View e-Book
- Other Authors
- Terada, Yoshio
- Wada, Takashi
- Doi, Kent
- Responsibility
- Yoshio Terada, Takashi Wada, Kent Doi, editors
- Place of Publication
- Singapore
- Publisher
- Springer
- Date of Publication
- c2020
- Physical Description
- 1 online resource (ix, 396 p.) : 39 illus., 33 illus. in color
- ISBN
- 9789811511080
- 9789811511073 (Print ed.)
- 9789811511097 (Print ed.)
- 9789811511103 (Print ed.)
- Subjects (MeSH)
- Acute Kidney Injury - etiology
- Acute Kidney Injury - therapy
- Regenerative Medicine - methods
- Specialty
- Nephrology
- Regenerative Medicine
- Abstract
- This book presents up-to-date information on the clinical-pathophysiological features of acute renal injury and discusses the KDIGO diagnostic criteria, as well as novel experimental findings, including in the area of regenerative medicine. It also highlights the clinical-pathophysiological importance of AKI in clinical settings, including differential diagnoses and management of AKI. In the past, the pathology associated with sudden renal impairment was characterized as acute renal failure (ARF). However, in the 2000s, the joint efforts of specialists in fields including nephrology, intensive care medicine, and cardiovascular medicine led to the introduction of a novel concept known as acute kidney injury (AKI). As medical care progressed, patients such as high-risk elderly subjects who were not deemed to be candidates for invasive therapy came to be treated in intensive care units (ICUs). As a result, kidney injury as a subset of multiple organ failure was re-considered as AKI, especially in intensive care medicine. AKI was then proposed as a novel disease concept to emphasize the importance of early diagnosis and early intervention to improve prognosis. Presenting novel features, such as the definition of AKI, risk factors and management; biomarkers, such as neutrophil gelatinase-associated lipocalin (NGAL) and L-type fatty acid-binding protein (L-FABP); long-term outcomes of AKI; as well as renal regeneration using iPS cell, manipulation of embryonic genes, and Xenotransplanted embryonic kidney, this book is of interest to all physicians and researchers in this field around the globe.
- Contents
- Part I. Diagnosis and Risk Factors of AKI -- 1. Acute Kidney Injury: Definition and Epidemiology -- 2. Causes of AKI (Prerenal, Intrarenal, Postrenal) -- 3. Pathophysiology of AKI -- 4. Diagnosis of AKI: Clinical Assessment, Novel Biomarkers, History, and Perspectives -- 5. Risk Factors for AKI Development in Surgery (Non-cardiac Surgery) -- 6. Risk Factors for AKI Development in Acute Decompensated Heart Failure -- 7. Contrast-Induced Acute Kidney Injury -- 8. Antibiotics- and Immunosuppressants-Related AKI -- 9. AKI in Setting of Cancer -- 10. Community- and Hospital-Acquired Acute Kidney Injury -- Part II. Complication of AKI -- 11. Complication of Homeostasis (Electrolytes and Acid-Base) -- 12. Volume Overload and Pulmonary Complications -- Part II.I Prevention and Management of AKI -- 13. Prophylaxis and Management of Acute Kidney Injury -- 14. Postrenal AKI -- 15. Acute Kidney Injury in Intensive Care Medicine -- 16. Nondialytic Supportive Management of AKI -- 17. Renal Replacement Therapy in AKI -- 18. Short-Term and Long-Term Outcomes of AKI Patients -- 19. Management of Pediatric AKI -- Part IV. Experimental Novel Findings -- 20. AKI-to-CKD Transition -- 21. Role of the Nervous System in Acute Kidney Injury -- 22. AKI and Immune System -- 23. Acute Kidney Injury and Cytokines -- Part V. AKI and Regenerative Medicine -- 24. iPS Cell and Renal Regenerative Medicine -- 25. Kidney Development and Injury: A Road to Regeneration -- 26. Xenotransplanted Embryonic Kidney.
- Format
- e-Book
- Location
- Online
Biosimilars : a new generation of biologics
https://libcat.nshealth.ca/en/permalink/provcat32473
Jean-Louis Prugnaud, Jean-Hugues Trouvin, editors.
--Paris:
Springer
, c2013.
- Available Online
- View e-Book
- Location
- Online
Biologics have revolutionised the treatment of many severe conditions, delivering exceptional clinical results but also producing exceptionally high prices. As patents expire, copies and price competition are expected throughout the world. However, due to the intrinsic heterogeneity and molecular complexity of biologic medicinal products, their copies cannot simply be authorized under the "generic rule" valid for small chemical entities. In response, a dedicated regulation was issued in the Eur…
- Available Online
- View e-Book
- Other Authors
- Prugnaud, Jean-Louis
- Trouvin, Jean-Hugues
- Responsibility
- Jean-Louis Prugnaud, Jean-Hugues Trouvin, editors
- Place of Publication
- Paris
- Publisher
- Springer
- Date of Publication
- c2013
- Physical Description
- 1 online resource (xvii, 87 p. : 7 ill., 5 ill. in color)
- ISBN
- 9782817803364
- Subjects (MeSH)
- Biosimilar Pharmaceuticals
- Subjects (LCSH)
- Immunology
- Pharmaceutical technology
- Pharmacy
- Nephrology
- Oncology
- Abstract
- Biologics have revolutionised the treatment of many severe conditions, delivering exceptional clinical results but also producing exceptionally high prices. As patents expire, copies and price competition are expected throughout the world. However, due to the intrinsic heterogeneity and molecular complexity of biologic medicinal products, their copies cannot simply be authorized under the "generic rule" valid for small chemical entities. In response, a dedicated regulation was issued in the European Union. It is based on the concept of "biological medicinal products similar to a biological reference product", or "biosimilars". This book analyses the context of biotechnological production and addresses the European legal framework for biosimilar market approval. It highlights post-market authorisation issues, such as Risk Management Plans and substitution of products, and outlines some other issues, such as cost management and international nomenclature.This book is primarily intended for hospital-based physicians and pharmacists. It will also be a valuable resource for all actors from all countries who want to better understand the emergence of these new medicinal products within the European context.
- Contents
- Biologicals’ Characteristics -- From the Biosimilar Concept to the Marketing Authorisation -- Substitution and Interchangeability -- G-CSFs: Onco-Hematologist’s Point of View -- The Oncologist’s Point of Biosimilars: Challenges Raised by Biosimilars: Who is Responsible for Cost and Risk Management? -- Afterword.
- Format
- e-Book
- Location
- Online
Clinical management of urolithiasis
https://libcat.nshealth.ca/en/permalink/provcat32495
Thomas Knoll, Margaret S. Pearle, editors.
--Berlin, Heidelberg:
Springer
, c2013.
- Available Online
- View e-Book
- Location
- Online
The prevalence and incidence of urolithiasis are rising worldwide. Accordingly, the diagnosis, management, and prevention of urinary calculi are relevant to all urologists. A host of new technologies, techniques, and medical regimens have been introduced over the past 30 years, from novel imaging procedures and medical expulsive therapy to interventional treatment options. The contemporary urologist should be familiar with and adept at implementing these new concepts and techniques. Furthermore…
- Available Online
- View e-Book
- Other Authors
- Knoll, Thomas
- Pearle, Margaret S
- Responsibility
- Thomas Knoll, Margaret S. Pearle, editors
- Place of Publication
- Berlin, Heidelberg
- Publisher
- Springer
- Date of Publication
- c2013
- Physical Description
- 1 online resource (x, 222 p. : 60 ill., 53 ill. in color)
- ISBN
- 9783642287329
- Subjects (MeSH)
- Nephrolithiasis - therapy
- Subjects (LCSH)
- Internal medicine
- Nephrology
- Surgery
- Urology
- Abstract
- The prevalence and incidence of urolithiasis are rising worldwide. Accordingly, the diagnosis, management, and prevention of urinary calculi are relevant to all urologists. A host of new technologies, techniques, and medical regimens have been introduced over the past 30 years, from novel imaging procedures and medical expulsive therapy to interventional treatment options. The contemporary urologist should be familiar with and adept at implementing these new concepts and techniques. Furthermore, urologists should be comfortable with the comprehensive metabolic evaluation of high-risk patients and the initiation of dietary or medical preventive measures. This book covers every clinically relevant aspect of urolithiasis and its treatment, both surgical and medical. In addition to providing up-to-date evidence-based recommendations regarding stone management, it reflects the real-life experience of well-known international experts. Each chapter includes tables and algorithms that allow the reader easily to check the requirements for specific procedures and to translate them into clinical practice. Clinical Management of Urolithiasis will serve as an ideal practical guide and source of information for use in everyday clinical routine.
- Format
- e-Book
- Location
- Online
Contemporary Kidney Transplantation
https://libcat.nshealth.ca/en/permalink/provcat43128
Carlo Gerardo B. Ramirez, Jerry McCauley, editors.
--Cham:
Springer
, c2018.
- Available Online
- View e-Book
- Location
- Online
This book provides a comprehensive guide to successful kidney transplantation in the highly regulated environment of today. It covers the history of kidney transplant to highlight innovations that have made kidney transplantation so successful as well as the new deceased donor kidney allocation strategy and postulates what types of changes might occur with this new policy. The book highlights special areas of nephrology concern in kidney transplantation, especially diseases likely to recur foll…
- Available Online
- View e-Book
- Other Authors
- Ramirez, Carlo Gerardo B.
- McCauley, Jerry
- Responsibility
- Carlo Gerardo B. Ramirez, Jerry McCauley, editors
- Place of Publication
- Cham
- Publisher
- Springer
- Date of Publication
- c2018
- Physical Description
- 1 online resource (xvii, 437 p.) : 103 illus., 74 illus. in color
- Series Title
- Springer reference
- Organ and tissue transplantation
- ISBN
- 9783319196176
- 9783319196169 (print ed.)
- ISSN
- 2570-1592
- Subjects (MeSH)
- Kidney Transplantation
- Specialty
- Nephrology
- Transplantation
- Notes
- "eReference"--Publisher.
- Abstract
- This book provides a comprehensive guide to successful kidney transplantation in the highly regulated environment of today. It covers the history of kidney transplant to highlight innovations that have made kidney transplantation so successful as well as the new deceased donor kidney allocation strategy and postulates what types of changes might occur with this new policy. The book highlights special areas of nephrology concern in kidney transplantation, especially diseases likely to recur following transplant. It deals with many of the medications used in kidney transplantation including different commonly used antirejection protocols. It also provides a complete reference on the various operations involved in kidney transplantation. The text includes detailed pictures and surgical technique sections on cadaveric kidney transplantation and living kidney transplantation. It includes information on living kidney donation surgery with a chapter dedicated to the minimally invasive techniques that have been popularized in the last fifteen years. Some coverage on open living kidney donation is presented. Included in this section is discussions of how to handle certain operative challenges like severe atherosclerosis, venous sclerosis and various urinary system aberrancies. Comprehensive coverage of common surgical complications is presented including management of urinary strictures, urinary leaks, lymphoceles, vascular problems following transplant, and what steps shoul d be taken when an early kidney transplant biopsy is necessary. It also covers in detail what is required for maintenance of health after kidney transplantation including the major risks for graft loss as well as what disease processes kidney transplant patients are particularly vulnerable to.
- Contents
- History of kidney transplantation -- Recipient Selection -- Indications and contraindications -- Evaluation and selection -- Special considerations in highly sensitized candidates -- Waitlist maintenance -- Donor Selection -- Living donor -- Deceased donor -- Standard criteria donors -- Extended criteria donors -- HBsAg, HBcAb+, HCV donors -- CDC high risk donors -- Donors on ECMO -- Surgical Technique -- Organ preservation and preparation -- Recipient kidney transplantation surgical technique -- Live donor nephrectomy -- Kidney Transplantation with other organs -- Anesthesia Management -- Organ Procurement Organization and New Kidney Allocation -- History and rationale for the change -- Recent changes and what they will mean -- Allocation policies in EU, UK, and other countries -- Geographic Variations in Kidney Access- Final Rule Wida (UNOS) -- Vulnerable Populations -- Special Consideration in Living Donor Kidney Transplantation -- Necessary components of a living donor team -- Living kidney donor paired exchanges -- Early and Late Course after Kidney Transplantation -- Early complications after kidney transplantation -- Late complications after kidney transplantation -- Immunology of Kidney Transplantation -- Pathology of Kidney Transplantation -- Radiology of Kidney Transplantation -- Radiology in kidney transplantation -- The role of Interventional radiology -- Transplant Immunosuppression -- History of immunosuppression: an overview -- Special consideration -- Tolerance: The Holy grail of Transplantation -- Infection in Kidney Transplanation -- The Contemporary Successful Kidney Transplant Program -- The Regulatory Environment -- Quality measure of a contemporary kidney transplant program -- The role of transplant coordinators -- The finance of kidney transplantation -- Kidney transplantation in the third millennium in North America: the strategy for success -- Legal issues of transplant programs in North America in the third millennium -- Epidemiology of Kidney Transplantation -- Ethics of Transplantation -- Psychosocial and financial Aspects of Transplantation -- Pediatric Transplantation -- Special Topics -- Pregnancy after Kidney Transplantation -- Future Directions.
- Format
- e-Book
- Location
- Online
Critical Care Nephrology and Renal Replacement Therapy in Children
https://libcat.nshealth.ca/en/permalink/provcat42655
Akash Deep, Stuart L. Goldstein, editors.
--Cham:
Springer
, c2018.
- Available Online
- View e-Book
- Location
- Online
This book represents an invaluable resource for professionals for the diagnosis and treatment of acute kidney injury (AKI) in children and how to select and deliver the appropriate form of renal replacement therapy (RRT). Experts from all over the globe have come together to share their wide experience in the field of Critical Care Nephrology in children. Paediatric critical care nephrology is a complex and highly specialised field, presenting challenges and management strategies that are often…
- Available Online
- View e-Book
- Other Authors
- Deep, Akash
- Goldstein, Stuart L.
- Responsibility
- Akash Deep, Stuart L. Goldstein, editors
- Place of Publication
- Cham
- Publisher
- Springer
- Date of Publication
- c2018
- Physical Description
- 1 online resource (xxii, 456 p.) : 45 illus., 33 illus. in color
- ISBN
- 9783319902814
- 9783319902807 (print ed.)
- 9783319902821 (print ed.)
- Subjects (MeSH)
- Acute Kidney Injury
- Child
- Critical Care
- Renal Replacement Therapy
- Specialty
- Critical Care
- Nephrology
- Abstract
- This book represents an invaluable resource for professionals for the diagnosis and treatment of acute kidney injury (AKI) in children and how to select and deliver the appropriate form of renal replacement therapy (RRT). Experts from all over the globe have come together to share their wide experience in the field of Critical Care Nephrology in children. Paediatric critical care nephrology is a complex and highly specialised field, presenting challenges and management strategies that are often quite distinct from those seen in adult practice. Therefore, it is high time to address all the topics in the field of critical care nephrology in children in a unique book which is the first of its kind. This book covers the basics as well as advances in the field of Critical Care Nephrology. Each chapter is dedicated to practical aspects of a particular topic elucidating various management decision points. Each chapter is also accompanied with algorithms, figures and protocols in tabulated format. Information on how to manage specific conditions are contextualized with relevant background anatomy, physiology and biochemistry and practical examples. At the end of the chapter, there are key learning points. Paediatricians, nephrologists and paediatric intensivists, as well as paediatric critical care and nephrology nurses in all countries will find this book an invaluable reference text.
- Contents
- Part I. Acute Kidney Injury -- Evolution of acute kidney injury in the last 2 decades -- Renal function monitoring in a critically sick patient -- Acute kidney injury: definitions and epidemiology -- Biomarkers in AKI -- Neonatal AKI including new devices -- Sepsis associated AKI -- Acute kidney injury in a child after cardiopulmonary -- Bypass, post cardiac surgery and cardio-renal syndromes -- Acute kidney injury in stem cell transplant recipients -- Hemolytic uremic syndrome -- Acute kidney injury in liver disease -- Renal emergencies in PICU—electrolyte, acid base and blood pressure issues -- Nutrition in a child with acute kidney injury and on CRRT -- Outcomes and renal recovery -- Part II. Renal Replacement Therapy -- Continuous renal replacement therapy—Technology and basic concepts -- Timing of initiation of CRRT -- Management considerations for the delivery of CRRT in children -- Anticoagulation in CRRT -- Haemodialysis -- Sustained low efficiency dialysis (SLED) and hybrid therapies: principles and management -- Peritoneal dialysis -- Plasmapheresis and total plasma exchange in the PICU -- Tandem therapies in extracorporeal support -- Pharmacology of drugs in critically ill patient with AKI and renal replacement therapy -- CRRT nursing programme Development -- Future of paediatric AKI and CRRT -- Part III. CRRT in Specific Disease States -- CRRT in a child in cardiac ICU -- CRRT in a child with sepsis and multi-organ failure -- Hyperammonaemia and inborn errors of metabolism (IEM) -- CRRT in exogenous intoxications -- CRRT in liver failure and other liver assist devices.
- Format
- e-Book
- Location
- Online
Endocrine hypertension : underlying mechanisms and therapy
https://libcat.nshealth.ca/en/permalink/provcat32443
Christian A Koch, George P Chrousos, editors.
--New York, NY:
Humana Press
, c2013.
- Available Online
- View e-Book
- Location
- Online
The prevalence of hypertension is almost three times as high as that of diabetes mellitus type 2, with both conditions being major risk factors for stroke, ischemic heart disease, cardiac arrhythmias, and heart failure. The exact prevalence of hypertension related to hormonal derangements (endocrine hypertension) is not known but estimated to affect less than 15% of hypertensive patients. Recent scientific discoveries have increased the understanding of the pathophysiologic mechanisms of hypert…
- Available Online
- View e-Book
- Other Authors
- Koch, Christian A
- Chrousos, George P
- Responsibility
- Christian A Koch, George P Chrousos, editors
- Place of Publication
- New York, NY
- Publisher
- Humana Press
- Date of Publication
- c2013
- Physical Description
- 1 online resource (xiii, 317 p. : 33 ill., 26 ill. in color)
- Series Title
- Contemporary endocrinology (Totowa, N.J.)
- ISBN
- 9781607615484
- Subjects (LCSH)
- Obstetrics
- Internal medicine
- Cardiology
- Endocrinology
- Nephrology
- Urology
- Abstract
- The prevalence of hypertension is almost three times as high as that of diabetes mellitus type 2, with both conditions being major risk factors for stroke, ischemic heart disease, cardiac arrhythmias, and heart failure. The exact prevalence of hypertension related to hormonal derangements (endocrine hypertension) is not known but estimated to affect less than 15% of hypertensive patients. Recent scientific discoveries have increased the understanding of the pathophysiologic mechanisms of hypertension. In Endocrine Hypertension, a renowned panel of experts provides a comprehensive, state-of-the-art overview of this disorder, discussing when to assign an endocrine cause in one of many conditions that may present with hypertension. The first part of Endocrine Hypertension is dedicated to adrenal causes. The second part of the volume concerns potential nonadrenal causes of hypertension, such as growth hormone excess or deficiency, primary hyperparathyroidism, vitamin D deficiency, testosterone deficiency, insulin resistance, obesity-associated hypertension, and the role of central mineralocorticoid receptors and cardiovascular disease. An important contribution to the literature, Endocrine Hypertension is an indispensable reference not only for endocrinologists, diabetologists, and adrenal investigators, but also for translational scientists and clinicians from cardiology, internal medicine, pediatrics, family medicine, geriatrics, urology, and reproductive medicine / gynecology.
- Contents
- Part I. Adrenal Hypertension -- Part II. Other Potential Causes of Endocrine Hypertension -- Index.
- Format
- e-Book
- Location
- Online
Fluid, electrolyte and acid-base disorders : clinical evaluation and management
https://libcat.nshealth.ca/en/permalink/provcat33396
Alluru S. Reddi.
--New York:
Springer
, c2014.
- Available Online
- View e-Book
- Location
- Online
Fluid, Electrolyte and Acid-Base Disorders: Clinical Evaluation & Management is a clear and concise presentation of the fundamentals of fluid, electrolyte and acid-base disorders frequently encountered in clinical practice. Each chapter begins with pertinent basic physiology followed by its clinical disorder. Cases for each fluid, electrolyte and acid-base disorder are discussed with answers. In addition, board-type questions with explanations are provided for each clinical disorder to increase…
- Available Online
- View e-Book
- Author
- Reddi, Alluru S
- Responsibility
- Alluru S. Reddi
- Place of Publication
- New York
- Publisher
- Springer
- Date of Publication
- c2014
- Physical Description
- 1 online resource (viii, 448 pages)
- ISBN
- 9781461490838 (electronic bk.)
- 9781461490821
- Subjects (MeSH)
- Body Fluids - metabolism
- Subjects (LCSH)
- Body Fluids - physiology
- Water-Electrolyte Imbalance - diagnosis
- Acid-Base Imbalance - diagnosis
- Body fluid disorders
- Body fluid disorders - Diagnosis
- Nephrology
- Abstract
- Fluid, Electrolyte and Acid-Base Disorders: Clinical Evaluation & Management is a clear and concise presentation of the fundamentals of fluid, electrolyte and acid-base disorders frequently encountered in clinical practice. Each chapter begins with pertinent basic physiology followed by its clinical disorder. Cases for each fluid, electrolyte and acid-base disorder are discussed with answers. In addition, board-type questions with explanations are provided for each clinical disorder to increase the knowledge for the clinician. Practical and clinically oriented, this book is a handy reference for practicing physicians, students, residents and fellows.
- Contents
- Body Fluid Compartments -- Interpretation of Urine Electrolytes and Osmolality -- Renal Handling of NaCl and Water -- Intravenous Fluids: Composition and Indications -- Diuretics -- Disorders of Extracellular Fluid Volume: Basic Concepts -- Disorders of ECF Volume: Congestive Heart Failure -- Disorders of ECF Volume: Cirrhosis of the Liver -- Disorders of ECF Volume: Nephrotic Syndrome -- Disorders of ECF Volume: Volume Contraction -- Disorders of Water Balance: Physiology -- Disorders of Water Balance: Hyponatremia -- Disorders of Water Balance: Hypernatremia -- Disorders of Potassium: Physiology -- Disorders of Potassium: Hypokalemia -- Disorders of Potassium: Hyperkalemia -- Disorders of Calcium: Physiology -- Disorders of Calcium: Hypocalcemia -- Disorders of Calcium: Hypercalcemia -- Disorders of Phosphate: Physiology -- Disorders of Phosphate: Hypophosphatemia -- Disorders of Phosphate: Hyperphosphatemia -- Disorders of Magnesium: Physiology -- Disorders of Magnesium: Hypomagnesemia -- Disorders of Magnesium: Hypermagnesemia -- Acid-Base Physiology -- Evaluation of an Acid-Base Disorder -- High Anion Gap Metabolic Acidosis -- Hyperchloremic Metabolic Acidosis: Renal Tubular Acidosis -- Hyperchloremic Metabolic Acidosis: Nonrenal Causes -- Metabolic Alkalosis -- Respiratory Acidosis -- Respiratory Alkalosis -- Mixed Acid-Base Disorders.
- Format
- e-Book
- Location
- Online
Kidney Cancer : Recent Advances in Surgical and Molecular Pathology
https://libcat.nshealth.ca/en/permalink/provcat45064
Mukul K. Divatia, Ayhan Ozcan, Charles C. Guo, Jae Y. Ro, editors.
--Cham:
Springer
, c2020.
- Available Online
- View e-Book
- Location
- Online
This book provides a comprehensive overview of pathology of kidney tumors along with radiological features and up to date treatment strategies that enable the readers to avail this information in day to day pathology sign-out as well as interaction with clinical colleagues of different disciplines. It also serves as a referral resource for the current medical or surgical practice while preparing for examinations or maintenance of certification. Written by experts in the field, chapters contain …
- Available Online
- View e-Book
- Other Authors
- Divatia, Mukul K.
- Ozcan, Ayhan
- Guo, Charles C.
- Ro, Jae Y.
- Responsibility
- Mukul K. Divatia, Ayhan Ozcan, Charles C. Guo, Jae Y. Ro, editors
- Place of Publication
- Cham
- Publisher
- Springer
- Date of Publication
- c2020
- Physical Description
- 1 online resource (xi, 445 p.) : 192 illus., 180 illus. in color
- ISBN
- 9783030283339
- 9783030283322 (Print ed.)
- 9783030283346 (Print ed.)
- 9783030283353 (Print ed.)
- Subjects (MeSH)
- Kidney Neoplasms - diagnosis
- Kidney Neoplasms - pathology
- Kidney Neoplasms - therapy
- Specialty
- Nephrology
- Pathology
- Surgical Oncology
- Abstract
- This book provides a comprehensive overview of pathology of kidney tumors along with radiological features and up to date treatment strategies that enable the readers to avail this information in day to day pathology sign-out as well as interaction with clinical colleagues of different disciplines. It also serves as a referral resource for the current medical or surgical practice while preparing for examinations or maintenance of certification. Written by experts in the field, chapters contain an updated review of important pathologic parameters mandated for diagnosis and reporting with emphasis on updated information regarding new developments in this interesting field. Numerous high-resolution color images aptly illustrate the various pathologic entities and their features as outlined in the text section along with tables that highlight the differential diagnoses and salient ancillary features. Kidney Cancer serves as a quick reference for all categories of readers alike, and provides up-to-date information on renal tumor pathology, radiology and management that are required in daily practice.
- Contents
- Part I. Clinical Aspects -- Surgical Considerations in Renal Tumors -- Renal Cell Carcinoma: The Oncologist’s Point of View -- Part II. Histopathology and Cytology -- Normal Anatomy and Histology of the Kidney: Importance for Kidney Tumors -- Benign Renal Epithelial / Epithelial and Stromal Tumors -- Major Subtypes of Renal Cell Carcinoma -- New and Emerging Subtypes of Renal Cell Carcinoma -- Renal Mass Biopsy -- Mesenchymal Kidney Tumors -- Pediatric Renal Tumors: Diagnostic Updates -- Neuroendocrine Kidney Tumors -- Hereditary Syndromes Associated with Kidney Tumors -- Lymphoid Neoplasms of the Kidney -- Tumors of the Renal Pelvis -- Non-Neoplastic Changes in Nephrectomy Specimens for Tumors -- Application of Immunohistochemistry in Diagnosis of Renal Cell Neoplasms -- Cytology of Kidney Tumors -- Part III. Diagnostic Imaging -- Diagnostic Imaging in Renal Tumors -- Part IV. Molecular Pathology -- Molecular Pathology of Kidney Tumors -- Targeted Treatment of Renal Cell Carcinoma -- Part V. Specimen Handling, Staging and Reporting -- Specimen Handling: Radical and Partial Nephrectomy Specimens -- Staging and Reporting of Renal Cell Carcinomas.
- Format
- e-Book
- Location
- Online
Kidney Disease in the Cardiac Catheterization Laboratory : A Practical Approach
https://libcat.nshealth.ca/en/permalink/provcat45302
Janani Rangaswami, Edgar V. Lerma, Peter A. McCullough, editors.
--Cham:
Springer
, c2020.
- Available Online
- View e-Book
- Location
- Online
This book is the first title that focuses exclusively on kidney disease and its impact in the cardiac catheterization laboratory. The increasing prevalence of vascular risk factors such as diabetes, obesity and hypertension coupled with increased longevity has resulted in a worldwide epidemic of cardiovascular and chronic kidney disease (CKD). Never has the impact of one organ system on the other been so profound, as in the current context of cardio-renal interactions. The cross talk between th…
- Available Online
- View e-Book
- Other Authors
- Rangaswami, Janani
- Lerma, Edgar V.
- McCullough, Peter A.
- Responsibility
- Janani Rangaswami, Edgar V. Lerma, Peter A. McCullough, editors
- Place of Publication
- Cham
- Publisher
- Springer
- Date of Publication
- c2020
- Physical Description
- 1 online resource (xx, 473 p.) : 59 illus., 40 illus. in color
- ISBN
- 9783030454142
- 9783030454135 (Print ed.)
- 9783030454159 (Print ed.)
- 9783030454166 (Print ed.)
- Subjects (MeSH)
- Cardiac Catheterization
- Cardio-Renal Syndrome - prevention & control
- Contrast Media - adverse effects
- Endovascular Procedures
- Renal Insufficiency, Chronic - complications
- Specialty
- Cardiology
- Nephrology
- Abstract
- This book is the first title that focuses exclusively on kidney disease and its impact in the cardiac catheterization laboratory. The increasing prevalence of vascular risk factors such as diabetes, obesity and hypertension coupled with increased longevity has resulted in a worldwide epidemic of cardiovascular and chronic kidney disease (CKD). Never has the impact of one organ system on the other been so profound, as in the current context of cardio-renal interactions. The cross talk between the heart and kidneys is highly relevant in the field of interventional cardiology, given the increasing number of trans-catheter procedures being performed in patients with underlying kidney disease. These procedures also have a significant impact on kidney function and require thoughtful interdisciplinary planning by a cardiorenal team, to achieve optimal outcomes This book assembles the collective expertise of several international leaders in the field of interventional cardiology and nephrology to summarize this complex interface. The book is divided into seven sections to comprehensively cover the topic, including sections on best practices with reduction of contrast associated acute kidney injury, cutting edge techniques to minimize kidney risk with complex interventions, impact of transcatheter valvular procedures on kidney function and the utility of cardio-nephrology teams. Less recognized complications with high morbidity such as athero-embolic renal disease are featured prominently, to increase awareness in the interventional cardiology and nephrology communities. This book is a valuable resource for interventional and structural cardiologists, general cardiologists and nephrologists dealing with the significant overlap areas between these two specialties. It is also relevant to medical students, trainee physicians in nephrology and cardiology, advanced care practitioners and nursing personnel in both specialties . Given the major impact of kidney function on outcomes in patients undergoing cardiac procedures, this textbook serves as a focal point to integrate relevant clinical data from both specialties and help interventional cardiologists achieve optimal outcomes, especially in patients with (or at risk for) kidney disease.
- Contents
- Part I. Atherosclerotic Cardiovascular Disease Burden in Chronic Kidney Disease -- 1. The Burden of Coronary Artery Disease in Chronic Kidney Disease -- 2. Non-invasive Testing in the Diagnosis of Ischemic Heart Disease in CKD: Scope, Pitfalls, and Future Directions -- 3. Peripheral Arterial Disease in Chronic Kidney Disease: Disease Burden, Outcomes, and Interventional Strategies -- 4. Cardiovascular Impact of Atherosclerotic Renovascular Disease -- Part II. Therapeutic Considerations with Revascularization in Chronic Kidney Disease -- 5. Therapeutic Considerations with Revascularization in Chronic Kidney Disease: Radial Versus Femoral Arterial Access -- 6. Antiplatelet Agent Choice and Platelet Function Testing in CKD -- 7. Choice of Stents and Clinical Outcomes in Patients with Chronic Kidney Disease -- 8. Revascularization Strategies in Chronic Kidney Disease: Percutaneous Coronary Interventions Versus Coronary Artery Bypass Graft -- 9. Approach to Revascularization in the Potential Kidney Transplant Recipient -- 10. Nephrology Consultative Approach and Risk Stratification Prior to Revascularization in Chronic Kidney Disease -- Part III. Acute Kidney Injury in the Catheterization Laboratory: Part I -- 11. Contrast-Induced Acute Kidney Injury: Epidemiology, Risk Stratification, and Prognosis -- 12. Pathophysiology of Contrast Induced Acute Kidney Injury -- 13. Prevention of Contrast-Induced AKI: Summary of Volume Optimization Strategies -- 14. Operator and Intraprocedural Strategies to Reduce Contrast-Induced Acute Kidney Injury -- Part IV. Acute Kidney Injury in the Catheterization Laboratory: Part II -- 15. Effect of Acute Mechanical Circulatory Support on Kidney Function -- 16. Renal Athero-embolic Disease: An Underdiagnosed Entity in Cardiac Catheterization -- 17. Acute Kidney Injury After Transcatheter Aortic Valve Replacement -- 18. Impact of Kidney Disease on Catheter-Based Mitral Valve Interventions -- 19. Contrast-Induced Nephropathy After Peripheral Vascular Intervention -- Part V. Catheter Based Reno-Vascular Interventions -- 20. Renal Artery Stenosis: State of the Art in the Diagnosis and Management -- 21. Renal Denervation: Physiology, Scope, and Current Evidence -- 22. Forced Matched Diuresis: Role in Renal Protection in the Cardiac Catheterization Laboratory -- Part VI. Role of Hemodynamic Evaluation in the Catheterization Laboratory -- 23. Traditional and Novel Invasive Hemodynamic Indices in the Evaluation of Congestive Heart Failure in Cardiorenal Syndrome -- 24. Pulmonary Hypertension in Chronic Kidney Disease -- Part VII. Utility of the Cardio-Nephrology Collaborative in the Cardiac Catheterization Laboratory -- 25. The Economic Impact of Kidney Disease in the Cardiac Catheterization Laboratory -- 26. Biomarkers of Acute Kidney Injury and Scope of Utilization in the Cardiac Catheterization Laboratory -- 27. A Call to Action to Develop Integrated Curricula in Cardiorenal Medicine.
- Format
- e-Book
- Location
- Online
New strategies to advance pre/diabetes care : integrative approach by PPPM
https://libcat.nshealth.ca/en/permalink/provcat32643
Mahmood S. Mozaffari, editor.
--Dordrecht:
Springer
, c2013.
- Available Online
- View e-Book
- Location
- Online
The writings of earliest civilizations reveal that diabetes mellitus has afflicted man for a very long time. Unfortunately, however, we are now experiencing a world-wide pandemic of the disease which has not been adequately addressed. Available evidence suggests that worldwide every 10 seconds one patient dies of diabetes and its severe complications. The outlook is even more bleak with the prediction of half of a billion diabetic patients by the year 2030. The cost-impact of the disease poses …
- Available Online
- View e-Book
- Other Authors
- Mozaffari, Mahmood S
- Responsibility
- Mahmood S. Mozaffari, editor
- Place of Publication
- Dordrecht
- Publisher
- Springer
- Date of Publication
- c2013
- Physical Description
- 1 online resource (xvii, 538 p. : 146 ill., 116 ill. in color)
- ISBN
- 9789400759718
- Subjects (MeSH)
- Diabetes Mellitus - prevention & control
- Individualized Medicine - methods
- Prediabetic State - prevention & control
- Preventive Medicine - methods
- Subjects (LCSH)
- Medicine
- Diabetes
- Endocrinology
- Metabolic diseases
- Nephrology
- Cytology
- Abstract
- The writings of earliest civilizations reveal that diabetes mellitus has afflicted man for a very long time. Unfortunately, however, we are now experiencing a world-wide pandemic of the disease which has not been adequately addressed. Available evidence suggests that worldwide every 10 seconds one patient dies of diabetes and its severe complications. The outlook is even more bleak with the prediction of half of a billion diabetic patients by the year 2030. The cost-impact of the disease poses a major challenge for both developed and developing countries and their economies. Thus, it is high time to reconsider and revise the current strategies in diabetes care. Accordingly, a paradigm shift from reactive to perspective medicine has become a timely consideration. This shift is based on the concept of Predictive, Preventive and Personalized Medicine (PPPM). The rationale for PPPM relates to the recognition that prediction of persons at high risk for the disease (i.e., diabetes mellitus) should help devise strategies to prevent its target organ complications, and create effective treatments tailored to the individual patient, thereby reducing morbidity, and associated costs, and mortality. The current book entitled 'New Strategies to Advance Pre/Diabetes Care: Integrative Approach by PPPM' is intended to serve as a reference source for researchers and the healthcare industry with a special emphasis on health promotion in the general population and help design innovative strategies to prevent the onset of diabetes mellitus and its secondary complications.
- Contents
- Global Figures Argue in Favour of Preventive Measures and Personalised Treatment to Optimise Diabetes Care -- Three Levels of Prediction, Prevention & Individualised Treatment Algorithms to Advance Diabetes Care: Integrative Approach -- Diabetes mellitus: new challenges and innovative therapies -- Identification of Biomarkers for beta cell failure as detection tools for predictive screening in type 2 pre-Diabetes -- Endothelial dysfunction in diabetes: role of circulating biomarkers as potential diagnostic and prognostic tolls -- Endothelial progenitor dysfunction in the pathogenesis of diabetic retinopathy: treatment concept to correct diabetes-associated deficits -- Oxidative stress and apoptotic biomarkers in diabetic retinopathy -- Diabetic Retinopathy: the Need for Predictive, Preventive and Personalized Approach to Management -- The role of inflammatory cytokines in diabetic nephropathy: Potential use as predictive markers for early detection and progression -- Preventing hyperglycemia and tissue injury in diabetes: The dynamic role of 2,3 dioxygenase in diabetes and its complications -- An Integrative Approach to Chronic Wounds in Patients with Diabetes: PPPM in Action -- Understanding inflammation as the key to targeted preventive measures for diabetes in relation to periodontics -- Cancer predisposition in diabetics: risk assessment and targeted preventive measures -- Recognition of individual risks by analysis of subcellular imaging insights into chromium picolinate therapy in pre/diabetes care, search into its safety and opinion controversy -- Remote control in diabetes -- Drug delivery systems for predictive medicine: polymers as tools for advanced application -- Author Index -- Subject Index.
- Format
- e-Book
- Location
- Online
Practical nephrology
https://libcat.nshealth.ca/en/permalink/provcat33452
Mark Harber, editor.
--London:
Springer
, c2014.
- Available Online
- View e-Book
- Location
- Online
This book will provide readers with a practice-based approach to all aspects of clinical nephrology. Written by experts in the field, Practical Nephrology offers invaluable practical advice on how to manage specific illnesses and, uniquely, the importance of establishing systems and processes to improve patient safety, enhance the patient pathway and guidance on how to systematically improve clinical governance. A unique aspect of this book are the tips and tricks and, suggestions for avoiding …
- Available Online
- View e-Book
- Other Authors
- Harber, Mark
- Responsibility
- Mark Harber, editor
- Place of Publication
- London
- Publisher
- Springer
- Date of Publication
- c2014
- Physical Description
- 1 online resource (xix, 901 pages)
- ISBN
- 9781447155478 (electronic bk.)
- 9781447155461
- Subjects (MeSH)
- Kidney Diseases
- Nephrology - methods
- Abstract
- This book will provide readers with a practice-based approach to all aspects of clinical nephrology. Written by experts in the field, Practical Nephrology offers invaluable practical advice on how to manage specific illnesses and, uniquely, the importance of establishing systems and processes to improve patient safety, enhance the patient pathway and guidance on how to systematically improve clinical governance. A unique aspect of this book are the tips and tricks and, suggestions for avoiding common errors based on the vast experience of the authors. In addition, the Editor has collated a list of links to international registries and guidelines as well as selected disease specific organisations, providing both clinicians and patients with access to helpful and recommended resources. Designed and written in a user-friendly fashion, Practical Nephrology will be the definitive reference for practising nephrologists, trainees and non-nephrologist who encounter renal patients in their daily practice.
- Contents
- Assessment of the Renal Patient -- Urine Analysis -- Imaging in Nephrology -- Kidney Biopsy -- Acute Kidney Injury: Epidemiology and Assessment -- Acute Kidney Injury: Management and Prevention -- Acute Renal Replacement Therapy -- Hepatorenal Syndrome -- Common Electrolyte Disorders -- Acid-Base Disorders -- Diagnosis and Investigation of the Hypertensive Patient -- Management of High Blood Pressure -- Podocytopathies -- Management of the Nephrotic Patient: The Overall Approach to the Patient with Nephrotic Syndrome (NS) -- Management of the Nephrotic Patient: Treatment of ECF Volume Expansion Due to Nephrotic Syndrome in Adults -- Minimal Change Disease and Focal Segmental Glomerulosclerosis -- Membranous Nephropathy -- Membranoproliferative Glomerulonephritis and C3 Glomerulopathy -- IgA Nephropathy and Henoch-Schonlein Purpura -- Systemic Small Vessel Vasculitis -- Goodpasture's or Anti-glomerular Basement Membrane (GBM) Disease -- Systemic Lupus Erythematosus, Antiphospholipid Syndrome and the Kidney -- Practical Immunosuppression Guidelines for Patients with Glomerulonephritis -- Infectious Diseases and the Kidney -- Blood-Borne Viruses and the Kidney -- Tubulointerstitial Nephritis -- Rheumatological Conditions and the Kidney -- Multiple Myeloma and the Kidney -- Amyloidosis -- Thrombotic Microangiopathies -- Sickle Cell Disease and Other Haematological Disorders Involving the Kidney -- Diabetes and the Kidney -- Pregnancy and the Kidney -- Disease of the Renal Vessels -- Urinary Tract Infection -- Renal Stone Disease -- Congenital Anomalies of the Kidneys and Urinary Tract -- Acquired Urinary Tract Obstruction -- Kidney Cancer -- Inherited Renal Tumour Syndromes -- Polycystic Kidney Disease -- Other Cystic Kidney Diseases -- Genetic Disorders of the Glomerular Basement Membrane -- Anderson-Fabry Disease and Other Inherited Lipid Disorders of the Kidney -- Inherited Metabolic Disease -- Dermatology in Kidney Disease -- Chronic Kidney Disease: Epidemiology and Causes -- Chronic Kidney Disease: Management -- Transition -- Anaemia Management in Chronic Kidney Disease -- Chronic Kidney Disease: Mineral and Bone Disorder (CKD-MBD) -- Chronic Kidney Disease: Cardiovascular Complications -- Coagulation in Kidney Disease -- Symptom Control and Palliative Care in Advanced CKD -- Nutrition and Kidney Disease -- Pharmacology and the Kidney -- Prevention of Infection in Kidney Patients -- Setting Up and Running a Haemodialysis Service -- Vascular Access: Improving Outcomes for Haemodialysis Patients -- Vascular Access: Fistulae and Grafts -- Complications of Maintenance Haemodialysis and How to Avoid Them -- Providing a Peritoneal Dialysis Service -- Peritoneal Dialysis Prescription -- Complications of Peritoneal Dialysis and How to Avoid Them -- Assessment of the Potential Transplant Donor -- Assessment of the Potential Transplant Recipient -- Tissue Typing, Crossmatch and Antibody Incompatibility in Kidney Transplantation -- Surgical Aspects of Kidney and Pancreas Transplantation -- Management of the Acute Transplant -- Immunosuppression for Kidney Transplantation -- Infectious Complications of Transplantation -- Long-Term Management of Kidney Transplant Recipients (KTRs) -- International Health Partnerships.
- Format
- e-Book
- Location
- Online
