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7.0 Tesla MRI brain atlas : in-vivo atlas with cryomacrotome correlation

https://libcat.nshealth.ca/en/permalink/provcat33652
Zang-Hee Cho, editor. (Second edition) --Berlin: Springer , c2015.
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The inaugural publication of the 7.0 Tesla MRI Brain Atlas: In-vivo Atlas with Cryomacrotome Correlation in 2010 provided readers with a spectacular source of ultra-high resolution images revealing a wealth of details of the brainstem and midbrain structures. This second edition contributes additional knowledge gained as a result of technologic advances and recent research. To facilitate identification and comparison of brain structures and anatomy, a detailed coordination matrix is featured in…
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Other Authors
Cho, Zang-Hee
Responsibility
Zang-Hee Cho, editor
Edition
Second edition
Place of Publication
Berlin
Publisher
Springer
Date of Publication
c2015
Physical Description
1 online resource (xxvi, 544 pages)
ISBN
9783642543982 (electronic bk.)
9783642543975
Subjects (MeSH)
Brain - anatomy & histology
Brain - diagnostic imaging
Magnetic Resonance Imaging - methods
Radiography
Subjects (LCSH)
Brain - Magnetic resonance imaging - Atlases
Abstract
The inaugural publication of the 7.0 Tesla MRI Brain Atlas: In-vivo Atlas with Cryomacrotome Correlation in 2010 provided readers with a spectacular source of ultra-high resolution images revealing a wealth of details of the brainstem and midbrain structures. This second edition contributes additional knowledge gained as a result of technologic advances and recent research. To facilitate identification and comparison of brain structures and anatomy, a detailed coordination matrix is featured in each image. Updated axial, sagittal, and coronal images are also included. This state-of-the-art and user-friendly reference will provide researchers and clinicians with important new perspectives.
Contents
Foreword -- Preface -- Preface of the 2nd Edition -- Introduction -- 1. Reference of Brain Image Setting -- 2. Orientation of Brain Images -- I. Orientation of the image sections and planes -- II. Standard of the sectional brain image planes and sizes -- III. Adjustment of MRI brain to the reference brain -- IV. Terminology & Labeling -- V. Data collection system for clinicopathologic brain mapping -- VI. Figures (Figs. 1, 2, 3) -- 3. Sources of Brain Images -- I. In vivo Images using 7.0T MRI -- II. Cadaver Images by Cryomacrotome -- III. Image reconstruction and volume rendering -- 4. 3D Images by Volume Rendering -- I. Coronal, Sagittal and Axial Cuts- Cadaver (Fig. 4) -- II. Coronal, Sagittal and Axial Cuts- MRI (Fig. 5) -- III. Sulcus and Gyrus- MRI (Fig. 6) -- IV.Brodmann areas-MRI (Fig. 7) -- Acknowledgements -- Chapter I. Coronal Images of Cadaver & Human Brain of 7.0T MRI In Vivo -- Chapter II. Sagittal Images of Cadaver & Human Brain of 7.0T MRI In Vivo -- Chapter III. Axial Images of Cadaver & Human Brain of 7.0T MRI In Vivo -- References -- Abbreviations -- Index.
Format
e-Book
Publication Type
Atlas
Location
Online
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7.0 Tesla MRI brain white matter atlas

https://libcat.nshealth.ca/en/permalink/provcat33655
Zang-Hee Cho, editor ; Fernando Calamante, Je-Geun Chi, co-editors. (Second edition) --Berlin: Springer , c2015.
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Online
The introduction of techniques that permit visualization of the human nervous system is one of the foremost advances in neuroscience and brain-related research. Among the most recent significant developments in this respect are ultra-high field MRI and the image post-processing technique known as track density imaging (TDI). It is these techniques (including super-resolution TDI) which represent the two major components of 7.0 Tesla MRI Çô Brain White Matter Atlas. This second edition of the at…
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Other Authors
Cho, Z.-H
Calamante, Fernando
Chi, Je-Geun
Responsibility
Zang-Hee Cho, editor ; Fernando Calamante, Je-Geun Chi, co-editors
Edition
Second edition
Place of Publication
Berlin
Publisher
Springer
Date of Publication
c2015
Physical Description
1 online resource (xxiii, 457 pages)
ISBN
9783642543920 (electronic bk.)
9783642543913
Subjects (MeSH)
Brain - anatomy & histology
Brain - diagnostic imaging
Magnetic Resonance Imaging - methods
White Matter - anatomy & histology
White Matter - diagnostic imaging
Radiography
Subjects (LCSH)
Brain - Magnetic resonance imaging - Atlases
Brain - Magnetic resonance imaging
Abstract
The introduction of techniques that permit visualization of the human nervous system is one of the foremost advances in neuroscience and brain-related research. Among the most recent significant developments in this respect are ultra-high field MRI and the image post-processing technique known as track density imaging (TDI). It is these techniques (including super-resolution TDI) which represent the two major components of 7.0 Tesla MRI Çô Brain White Matter Atlas. This second edition of the atlas has been revised and updated to fully reflect current application of these technological advancements in order to visualize the nervous system and the brain with the finest resolution and sensitivity. Exquisitely detailed color images offer neuroscientists, neurologists, and neurosurgeons a superb resource that will be of value both for the purpose of research and for the treatment of common brain diseases such as Alzheimer's disease and multiple sclerosis.
Contents
Introduction -- 1. MR Diffusion Tensor Imaging (DTI) and Track-Density Imaging (TDI) -- a. MR Diffusion Tensor Imaging (DTI) and Super-Resolution Track-Density Imaging (TDI) -- b. Track-Density Imaging (TDI) Examples of DTI and TDI-1 -- 2. Views, Directions, and Orientations of Brain Images -- a. Views and Directions of the Brain Image -- b. Definition of the Central Intercommissural Line -- c. Volume Rendered 3D Images -- Acknowledgments -- PART 1. Coronal Images of Tractography and Corresponding In-Vivo 7.0-T MRI Anatomy -- PART 2. Sagittal Images of Tractography and Corresponding In-Vivo 7.0-T MRI Anatomy -- PART 3. Axial Images of Tractography and Corresponding In-Vivo 7.0-T MRI Anatomy.
Format
e-Book
Publication Type
Atlas
Location
Online
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501 human diseases

https://libcat.nshealth.ca/en/permalink/provcat22610
Mullins, David. --Clifton Park, NY: Thomson Delmar Learning , 2006.
Call Number
WB 39 M959h 2006
Location
Nova Scotia Hospital
Halifax Infirmary
Call Number
WB 39 M959h 2006
Author
Mullins, David
Place of Publication
Clifton Park, NY
Publisher
Thomson Delmar Learning
Date of Publication
2006
Physical Description
426 p.
ISBN
1401825214
Subjects (MeSH)
Disease - Handbooks
Format
Book
Location
Nova Scotia Hospital
Halifax Infirmary
Copies
2
Loan Period
3 weeks
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ABC of transfusion

https://libcat.nshealth.ca/en/permalink/provcat23637
Contreras, Marcela. (4th ed.) --Chichester, England: Wiley-Blackwell/BMJ Books , 2009.
Call Number
WB 356 A134 2009
Location
Dickson Building
Call Number
WB 356 A134 2009
Author
Contreras, Marcela
Edition
4th ed.
Place of Publication
Chichester, England
Publisher
Wiley-Blackwell/BMJ Books
Date of Publication
2009
Physical Description
vii, 119 p.
Series Title
ABC series
ISBN
9781405156462
Subjects (MeSH)
Blood Transfusion
Transfusion Medicine
Contents
The blood donor: demographics, donor selection and tests on donor blood -- Supply and demand for blood and blood components, and stock management -- Compatibility testing before transfusion and blood ordering policies -- Transfusion of red cells -- Platelet and granulocyte transfusions -- Haemolytic disease of the newborn and its prevention -- Fetal and neonatal transfusion -- Plasma, plasma products and indications for their use (to include plasma exchange) -- Human albumin solutions and the controversy of crystalloids versus colloids -- The treatment of massive haemorrhage: in surgery and in trauma -- Immunological complications of transfusion -- Infectious complications of blood transfusion: bacteria and parasites -- Infectious complications of blood transfusion: viruses -- vCJD and its impact on the UK blood supply -- Risks of transfusion in the context of haemovigilance. SHOT: the UK haemovigilance system -- Alternatives to allogeneic blood transfusion including autologous transfusion -- Blood substitutes -- Appropriate use of blood and better blood transfusion -- Cellular and immunotherapies -- Blood transfusion in a regulatory environment and the EU directive.
Format
Book
Location
Dickson Building
Loan Period
3 weeks
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The ABCs of human behavior : behavioral principles for the practicing clinician

https://libcat.nshealth.ca/en/permalink/provcat23596
Ramnero, Jonas. --Oakland, CA: New Harbinger Publications , 2008.
Call Number
WM 105 R174a 2008
Location
Halifax Infirmary
Call Number
WM 105 R174a 2008
Author
Ramnero, Jonas
Other Authors
Torneke, Niklas
Place of Publication
Oakland, CA
Publisher
New Harbinger Publications
Date of Publication
2008
Physical Description
214 p.
ISBN
9781572245389
Subjects (MeSH)
Behavior Therapy - methods
Psychology, Clinical - methods
Conditioning, Operant
Learning
Format
Book
Location
Halifax Infirmary
Loan Period
3 weeks
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Abrahams' and McMinn's clinical atlas of human anatomy

https://libcat.nshealth.ca/en/permalink/provcat32239
by Peter H. Abrahams ... [et al.]. (8th ed.) --Edinburgh, UK: Elsevier , c2020.
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Location
Online
Abrahams' and McMinn’s Clinical Atlas of Human Anatomy, 8th Edition delivers the straightforward visual guidance you need to perform confidently in all examinations and understand spatial relationships required during your medical training, while also acquiring the practical anatomical knowledge needed for your future clinical career. Respected authority Prof. Peter Abrahams and his team of leading international anatomists and radiologists link a vast collection of clinical images to help you …
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Other Authors
Abrahams, Peter H.
Responsibility
by Peter H. Abrahams ... [et al.]
Edition
8th ed.
Alternate Title
McMinn and Abrahams' clinical atlas of human anatomy
Clinical atlas of human anatomy
Place of Publication
Edinburgh, UK
Publisher
Elsevier
Date of Publication
c2020
Physical Description
1 online resource, 412 p.
ISBN
9780702073328
Subjects (MeSH)
Anatomy - Atlases
Subjects (LCSH)
Human anatomy--Atlases
Specialty
Anatomy
Abstract
Abrahams' and McMinn’s Clinical Atlas of Human Anatomy, 8th Edition delivers the straightforward visual guidance you need to perform confidently in all examinations and understand spatial relationships required during your medical training, while also acquiring the practical anatomical knowledge needed for your future clinical career. Respected authority Prof. Peter Abrahams and his team of leading international anatomists and radiologists link a vast collection of clinical images to help you master all the essential correlations between the basic science of anatomy and its clinical practice.
Access
Registration required for PDF access.
Format
e-Book
Location
Online
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Abrahams' and McMinn's clinical atlas of human anatomy

https://libcat.nshealth.ca/en/permalink/provcat50319
Abrahams, Peter H. (8th ed.) --Edinburgh ; London: Elsevier , 2020.
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Location
Online
Available Online
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Author
Abrahams, Peter H.
Other Authors
Spratt, Jonathan D.
Loukas, Marios
Van Schoor, Albert-Neels
Edition
8th ed.
Place of Publication
Edinburgh ; London
Publisher
Elsevier
Date of Publication
2020
ISBN
9780702073328
Subjects (MeSH)
Anatomy
Notes
Access to this online resource is restricted to IWK Health Centre employees working from inside the hospital network.
Format
e-Book
Publication Type
Atlas
Location
Online
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Acceptable risk in biomedical research : European perspectives

https://libcat.nshealth.ca/en/permalink/provcat40982
Sigmund Simonsen. --Dordrecht: Springer , c2012.
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Location
Online
Available Online
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Author
Simonsen, Sigmund, 1972-
Responsibility
Sigmund Simonsen
Place of Publication
Dordrecht
Publisher
Springer
Date of Publication
c2012
Physical Description
1 online resource (xv, 293 p.)
Series Vol.
v. 50
Series Title
International library of ethics, law, and the new medicine
ISBN
9789400726789
9789400726772 (print ed.)
Subjects (MeSH)
Ethics, Research
Human Experimentation - ethics
Human Experimentation - legislation & jurisprudence
Risk Assessment - legislation & jurisprudence
Other Subjects
Europe
Contents
Part. I Initial Issues -- 1. Introduction -- 2. Method and Material -- 3. Initial Conceptual Clarifications -- 4. Origins of the Requirement of Proportionality -- 5. The Purpose of the Requirement of Proportionality -- Part II. Which Risks, Burdens, and Potential Benefits Are Relevant, and How Should They Be Estimated? -- 6. Introduction -- 7. Which Risks, Burdens and Potential Benefits Are Relevant? -- 8. How to Estimate Risks, Burdens, and Potential Benefits -- Part III. The Assessment of Proportionality -- 9. The Requirement of Proportionality – Initial Clarifications -- 10. Therapeutic Research -- 11. Nontherapeutic Research -- 12. Nontherapeutic Research on “Vulnerable” Participants -- 13. Non-interference with Necessary Clinical Interventions and The No Harm Rule -- 14. Especially on Randomised Clinical Trials, Including Placebo Controlled Clinical Trials -- 15. Acceptable Risks and Burdens to Others than the Participant -- 16. Later Developments During the Course of the Research -- 17. Legal Effects of the Requirement of Proportionality -- Part IV. Summary and Conclusions -- 18. Summary of Results -- 19. Recommendations -- 20. Perspectives -- Appendix A: Legal Instruments -- Appendix B: Case-Law -- Appendix C: Case Examples.
Format
e-Book
Location
Online
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Accidental Injury : Biomechanics and Prevention

https://libcat.nshealth.ca/en/permalink/provcat38971
(3rd ed.) --New York, NY: Springer , c2015.
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Location
Online
This book provides a state-of-the-art look at the applied biomechanics of accidental injury and prevention. The editors, Drs. Narayan Yoganandan, Alan M. Nahum and John W. Melvin are recognized international leaders and researchers in injury biomechanics, prevention and trauma medicine. They have assembled renowned researchers as authors for 29 chapters to cover individual aspects of human injury assessment and prevention. This third edition is thoroughly revised and expanded with new chapters …
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Other Authors
Yoganandan, Narayan
Nahum, Alan M
Melvin, John W
Edition
3rd ed.
Place of Publication
New York, NY
Publisher
Springer
Date of Publication
c2015
Physical Description
1 online resource (xviii, 851 p. : 389 illus., 143 illus. in color)
ISBN
9781493917327
9781493917310 (print ed.)
Subjects (MeSH)
Accidents
Biomechanical Phenomena
Wounds and Injuries - prevention & control
Abstract
This book provides a state-of-the-art look at the applied biomechanics of accidental injury and prevention. The editors, Drs. Narayan Yoganandan, Alan M. Nahum and John W. Melvin are recognized international leaders and researchers in injury biomechanics, prevention and trauma medicine. They have assembled renowned researchers as authors for 29 chapters to cover individual aspects of human injury assessment and prevention. This third edition is thoroughly revised and expanded with new chapters in different fields. Topics covered address automotive, aviation, military and other environments. Field data collection; injury coding/scaling; injury epidemiology; mechanisms of injury; human tolerance to injury; simulations using experimental, complex computational models (finite element modeling) and statistical processes; anthropomorphic test device design, development and validation for crashworthiness applications in topics cited above; and current regulations are covered. Risk functions and injury criteria for various body regions are included. Adult and pediatric populations are addressed. The exhaustive list of references in many areas along with the latest developments is valuable to all those involved or intend to pursue this important topic on human injury biomechanics and prevention. The expanded edition will interest a variety of scholars and professionals including physicians, biomedical researchers in many disciplines, basic scientists, attorneys and jurists involved in accidental injury cases, and governmental bodies. It is hoped that this book will foster multidisciplinary collaborations by medical and engineering researchers, and academicians and practicing physicians for injury assessment and prevention and stimulate more applied research, education and training in the field of accidental-injury causation and prevention.
Contents
Introduction to and applications of injury biomechanics -- Automotive field data in injury biomechanics -- Medical imaging and injury scaling in trauma biomechanics -- Anthropomorphic test devices and injury risk assessments -- Restraint system biomechanics -- Computational modeling in injury biomechanics -- Computational analysis of bone fracture -- Skull and facial bone injury biomechanics -- Biomechanics of brain injury: a historical perspective -- Biomechanics of brain injury: looking to the future -- Neck injury biomechanics -- Upper extremity biomechanics -- Thorax injury biomechanics -- Impact and injury response of the abdomen -- Thoracic spine injury biomechanics -- Lumbar spine injury biomechanics -- Knee, thigh, and hip injury biomechanics -- Leg, foot, and ankle injury biomechanics -- Pain biomechanics -- Thoracolumbar pain: neural mechanisms and biomechanics -- Role of muscles in accidental injury -- Pediatric biomechanics -- Best practice recommendations for protecting child occupants -- Pedestrian injury biomechanics and protection -- Design and testing of sports helmets: biomechanical practical considerations -- Normalization and scaling for human response corridors and development of injury risk curves -- Injury criteria and motor vehicle regulations -- Civil aviation crash injury protection -- Ballistic injury biomechanics.
Format
e-Book
Location
Online
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The active female : health issues throughout the lifespan

https://libcat.nshealth.ca/en/permalink/provcat33318
Jacalyn J. Robert-McComb, Reid L. Norman, Mimi Zumwalt, editors. (Second edition) --New York: Springer , c2014.
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Location
Online
The purpose of the The Active Female: Health Issues Throughout the Lifespan, 2nd Edition is twofold: (1) to increase the awareness of wellness and fitness issues for active females and their family members; and (2) to provide an avenue for medical practitioners, allied health professionals, health educators, and certified individuals in sports medicine to gain critical, updated knowledge of a field specific to active females. Part I of the book offers a foundation to help the reader understand …
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Other Authors
Robert-McComb, Jacalyn J
Norman, Reid L
Zumwalt, Mimi
Responsibility
Jacalyn J. Robert-McComb, Reid L. Norman, Mimi Zumwalt, editors
Edition
Second edition
Place of Publication
New York
Publisher
Springer
Date of Publication
c2014
Physical Description
1 online resource (xxiii, 595 pages)
ISBN
9781461488842 (electronic bk.)
9781461488835
Subjects (MeSH)
Health Promotion
Nutritional Physiological Phenomena
Physical Fitness
Women
Women's Health
Subjects (LCSH)
Women - Health and hygiene
Women - Nutrition
Physical fitness for women
Médecine
Abstract
The purpose of the The Active Female: Health Issues Throughout the Lifespan, 2nd Edition is twofold: (1) to increase the awareness of wellness and fitness issues for active females and their family members; and (2) to provide an avenue for medical practitioners, allied health professionals, health educators, and certified individuals in sports medicine to gain critical, updated knowledge of a field specific to active females. Part I of the book offers a foundation to help the reader understand the interrelationship among body image concerns, the female reproductive cycle, and musculoskeletal anatomy/physiology of females that makes their health risks and concerns unique. Reproductive health is discussed by a prominent researcher in reproduction/endocrinology. An overview of the Female Athlete Triad which is a syndrome of three interrelated conditions (isordered eating, menstrual disturbances and bone loss) is presented in Part II. Physicians and certified professionals in sports medicine discuss the individual components of the triad, relating not only to the athletic female but also to the recreationally active woman throughout the lifespan. In Part III, Prevention and management of common musculoskeletal injuries is addressed by a female orthopedic surgeon who sub-specializes in treating female athletes. Finally, appropriate exercise and nutritional guidelines for active females are discussed in Parts IV-V of the book by certified professionals and licensed physicians in sports medicine. An invaluable addition to the literature, The Active Female: Health Issues Throughout the Lifespan, 2nd Edition will be of great interest to physicians, allied health care practitioners, medical/other wellness educators, and students who are interested in advancing women's health issues. Sports medicine specialists, family practitioners, gynecologists, team physicians, residents in sports medicine, athletic trainers, health educators, nurses, physicians assistants, physical therapists, sport psychologists, counselors, athletic trainers, and other members of the sports medicine team should also find this title of significant interest.
Contents
[Machne generated contents note] pt. I Focusing on Active Female's Health Issues: Unique Gender Related Psychological and Physiological Characteristics of Females -- 1. Body Image Concerns Throughout the Lifespan / Marilyn Massey-Stokes -- 2. Reproductive Changes in the Female Lifespan / Reid L. Norman -- 3. Considerations of Sex Differences in Musculoskeletal Anatomy / C. Roger James -- 4. The Human Menstrual Cycle / Reid L. Norman -- 5. Abnormal Menstrual Cycles / Reid L. Norman -- 6. Nutritional, Physical, and Psychological Stress and Functional Amenorrhea / Melissa R. Inigo -- 7. Effects of the Menstrual Cycle on the Acquisition of Peak Bone Mass / Brittany Dowling -- pt. II Disordered Eating Issues in the Active Female -- 8. Menstrual Dysfunction Screening and Management for Active Females / Jennifer J. Mitchell -- 9. Eating Disorders and Disordered Eating: A Global Perspective / Maesy Indigo -- 10. Disordered Eating Issues in Active Children and Adolescence / Lesley Carraway -- 11. The Physiology of Anorexia Nervosa and Bulimia Nervosa / Annette Gary -- 12. The Female Athletic Triad: Disordered Eating, Amenorrhea, and Osteoporosis / Andrew Cisneros -- 13. Screening for Disordered Eating and Eating Disorders in Female Athletes / Jacalyn J. Robert-McComb -- 14. Evidence-Based Disordered Eating Prevention Programs for Active Females / Anna M. Tacon -- pt. III Prevention and Management of Common Musculoskeletal Injuries in Active Females -- 15. Prevention and Management of Common Musculoskeletal Injuries in Preadolescent and Adolescent Female Athletes / Brittany Dowling -- 16. Prevention and Management of Common Musculoskeletal Injuries in the Adult Female Athlete / Brittany Dowling -- 17. Prevention and Management of Common Exercise-Related Musculoskeletal Injuries During Pregnancy / Brittany Dowling -- 18. Prevention and Management of Common Musculoskeletal Injuries in the Aging Female Athlete / Brittany Dowling -- 19. Osteoporosis and Current Therapeutic Management / Kellie F. Flood-Shaffer -- pt. IV Exercise Guidelines and Precautions for Active Females -- 20. Traditional and Nontraditional Empirically Based Exercise Programs for Active Females / Anna M. Tacon -- 21. Cardiovascular Exercise Guidelines for Children and Adolescent Women / Maria Fernandez-del-Valle -- 22. Resistance Training Guidelines for Active Females Throughout the Lifespan: Children, Adolescences, Adult Women, and the Aging Woman / Tyrel S. McCravens -- 23. Exercise Precautions for the Female Athlete: Signs of Overtraining / Lauren Gates -- 24. Excessive Exercise and Immunity: The J-Shaped Curve / Anna M. Tacon -- 25. Screening Tools for Excessive Exercise in the Active Female / Maria Fernandez-del-Valle -- 26. Exercise Prescription and Pregnancy / Jacalyn J. Robert-McComb -- pt. V Nutrition, Energy Balance, and Weight Control -- 27. Estimating Energy Requirements / Eduardo Iglesias-Gutierrez -- 28. Nutritional Guidelines for Active Children / Eduardo Iglesias-Gutierrez -- 29. Nutritional Guidelines and Energy Needs for the Female Athlete: Preventing Low Energy Availability and Functional Amenorrhea Through Diet / Angela Garcia Gonzalez -- 30. Ergogenic Aids and the Female Athlete / Fernando Naclerio -- 31. Nutritional Guidelines and Energy Needs During Pregnancy and Lactation / Lesley Carraway -- 32. Nutritional Guidelines, Energy Balance, and Weight Control: Issues for the Aging Active Female / Jose E. Almaraz Marroquin.
Format
e-Book
Location
Online
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Active living, cognitive functioning, and aging

https://libcat.nshealth.ca/en/permalink/provcat22851
Poon, Leonard W. --Champaign, IL: Human Kinetics , 2006.
Call Number
WT 104 A267 2006
Location
Halifax Infirmary
Call Number
WT 104 A267 2006
Author
Poon, Leonard W
Other Authors
Chodzko-Zajko, Wojtek
Tomporowski, Phillip D
Place of Publication
Champaign, IL
Publisher
Human Kinetics
Date of Publication
2006
Physical Description
250 p.
Series Vol.
v. 1
Series Title
Aging, exercise, and cognition series
ISBN
0736057854
9780736057851
Subjects (MeSH)
Aging - physiology
Cognition - physiology - aged
Exercise - physiology - Aged
Health Behavior - Aged
Physical Fitness - Aged
Format
Book
Location
Halifax Infirmary
Loan Period
3 weeks
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Acute Lung Injury and Repair : Scientific Fundamentals and Methods

https://libcat.nshealth.ca/en/permalink/provcat41567
Lynn M. Schnapp, Carol Feghali-Bostwick, editors. --Cham: Humana Press , 2017.
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Location
Online
Acute Respiratory Distress Syndrome (ARDS) remains an important cause of morbidity and mortality worldwide, and the incidence is predicted to increase with the aging population Several clinical disorders can initiate ARDS, including pneumonia, sepsis, gastric aspiration and trauma but despite intense research over the past 40 years, we still have an incomplete understanding of the pathophysiology of the disease and treatment remains largely supportive. This book provides an overview of acute lu…
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Other Authors
Schnapp, Lynn M.
Feghali-Bostwick, Carol
Other Authors
American Thoracic Society
Responsibility
Lynn M. Schnapp, Carol Feghali-Bostwick, editors
Place of Publication
Cham
Publisher
Humana Press
Date of Publication
2017
Physical Description
1 online resource (viii, 185 pages) : 23 illus., 20 illus. in color
Series Title
Respiratory medicine
ISBN
9783319465272
9783319465258 (print ed.)
ISSN
2197-7372
Subjects (MeSH)
Acute Lung Injury - etiology
Models, Animal
Respiratory Distress Syndrome, Adult - physiopathology
Abstract
Acute Respiratory Distress Syndrome (ARDS) remains an important cause of morbidity and mortality worldwide, and the incidence is predicted to increase with the aging population Several clinical disorders can initiate ARDS, including pneumonia, sepsis, gastric aspiration and trauma but despite intense research over the past 40 years, we still have an incomplete understanding of the pathophysiology of the disease and treatment remains largely supportive. This book provides an overview of acute lung injury and repair, describes current animal models to study lung injury and reviews current methodologies to study and measure lung injury and repair. Special emphasis is given to state of the art techniques and methods and relevance to human disease. Acute Lung Injury and Repair: Scientific Fundamentals and Methods is a useful resource for physicians and scientists who are interested in experimental model systems for insight into ARDS pathogenesis and treatment strategies.
Contents
Methods to Study Lung Injury and Repair -- Mouse Models of Acute Lung Injury -- Transgenic Animal Models in Lung Research -- Fundamental Methods for Analysis of Acute Lung Injury in Mice -- Invasive Measurement of Pulmonary Function in Mice -- Analysis of Epithelial Injury and Repair -- Flow Cytometric Evaluation of Acute Lung Injury and Repair -- Lung Imaging in Animal Models -- Genetic and Genomic Approaches to Acute Lung Injury -- MicroRNA Analysis in Acute Lung Injury.
Format
e-Book
Location
Online
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Adenovirus Epithelial Keratitis and Thygeson's Superficial Punctate Keratitis : In Vivo Morphology in the Human Cornea

https://libcat.nshealth.ca/en/permalink/provcat31124
Helena M. Tabery. --Berlin, Heidelberg: Springer , c2012.
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Location
Online
Adenovirus epithelial keratitis and Thygeson's superficial punctate keratitis (TSPK) are apparently disparate diseases. While adenovirus eye infections are very common, caused by a known agent, and highly infectious, TSPK is comparatively rare, of unknown causation, and seemingly non-contagious. Despite these differences, the two diseases are often confused in clinical practice owing to the similarity between adenovirus epithelial infiltrates and 'coarse' epithelial TSPK lesions. This book pres…
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Other Authors
Tabery, Helena M
Responsibility
Helena M. Tabery
Place of Publication
Berlin, Heidelberg
Publisher
Springer
Date of Publication
c2012
Physical Description
1 online resource (x, 131 p. : 148 ill. in color)
ISBN
9783642216343
Subjects (MeSH)
Adenovirus Infections, Human
Corneal opacity - pathology
Epithelium, Corneal - pathology
Keratitis - pathology
Keratitis - case reports
Subjects (LCSH)
Ophthalmology
Abstract
Adenovirus epithelial keratitis and Thygeson's superficial punctate keratitis (TSPK) are apparently disparate diseases. While adenovirus eye infections are very common, caused by a known agent, and highly infectious, TSPK is comparatively rare, of unknown causation, and seemingly non-contagious. Despite these differences, the two diseases are often confused in clinical practice owing to the similarity between adenovirus epithelial infiltrates and 'coarse' epithelial TSPK lesions. This book presents the morphological features, dynamics, and sequelae of adenovirus and Thygeson's keratitides captured at high magnification in the living human cornea. It thereby fills the existing void between conventional photographs and slit-lamp observations. Case reports demonstrate the importance of patient history in differential diagnosis, illustrate the need for familiarity with early manifestations of adenovirus infections, and assist in the diagnosis of rare variants of TSPK. Furthermore, the detailed observations on the natural course of the diseases ensure that the book will serve not only as a diagnostic tool but also as a reference when evaluating the effects of potential new treatments.
Contents
Part I. Adenovirus Epithelial Keratitis -- 1. The Morphology of Adenovirus Epithelial Keratitis -- 2. Adenovirus Type 8 Epithelial Keratitis: The Development, Accompanying Signs, and Sequelae -- 3. Adenovirus Epithelial Keratitis Caused by Various Serotypes (Ad3, 4, and 7) -- 4. The Development of Subepithelial Infiltrates: A Sequence of Events -- Part II. Thygeson’s Superficial Punctate Keratitis -- 5. The Morphology of Thygeson’s Superficial Punctate Keratitis (TSPK) -- 6. Typical Cases of Thygeson’s Punctate Epithelial Keratitis (TSPK) -- 7. Three Atypical Cases of Thygeson’s Superfi cial Punctate Keratitis (TSPK).
Format
e-Book
Location
Online
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Adipose tissue and adipokines in health and disease

https://libcat.nshealth.ca/en/permalink/provcat33256
Giamila Fantuzzi, Theodore Mazzone, editors. (Second edition) --New York: Humana Press , c2014.
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The field of adipose tissue biology has been expanding at a very rapid pace in the last few years. Numerous advances have been made since publication of the first edition of this book, in terms of basic adipocyte biology, understanding of the determinants of obesity, distribution of body fat and weight loss, as well as the mechanisms linking excess adiposity to various co-morbidities. Adipose Tissue and Adipokines in Health and Disease, Second Edition contains updated chapters from the previous…
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Other Authors
Fantuzzi, Giamila
Mazzone, Theodore
Responsibility
Giamila Fantuzzi, Theodore Mazzone, editors
Edition
Second edition
Place of Publication
New York
Publisher
Humana Press
Date of Publication
c2014
Physical Description
1 online resource (xxvi, 372 pages)
Series
Nutrition and Health
Series Title
Nutrition and health (Totowa, N.J.)
ISBN
9781627037709 (electronic bk.)
9781627037693
Subjects (MeSH)
Adipocytes - physiology
Adipose Tissue - physiology
Obesity - complications
Obesity - etiology
Subjects (LCSH)
Adipose tissues
Fat cells
Adipocytes
Abstract
The field of adipose tissue biology has been expanding at a very rapid pace in the last few years. Numerous advances have been made since publication of the first edition of this book, in terms of basic adipocyte biology, understanding of the determinants of obesity, distribution of body fat and weight loss, as well as the mechanisms linking excess adiposity to various co-morbidities. Adipose Tissue and Adipokines in Health and Disease, Second Edition contains updated chapters from the previous volume but as the field has evolved, some areas covered in the first edition have been refocused to address the new knowledge. The volume is divided in four sections: the first two deal with basic adipose tissue and adipokine biology, while the last two address the problem of obesity and alterations in adipose tissue function from an epidemiological and clinical standpoint. The chapters are written by experts in their fields and include the most up to date scientific information. Adipose Tissue and Adipokines in Health and Disease, Second Edition is a useful resource for physicians interested in adipose tissue biology and basic scientists who want to know more about applied aspects of the field. The book targets endocrinologists, residents and fellows, internists, nutritionists and general practitioners who are exposed to an ever-expanding obese population.
Contents
Adipose Tissue: Structure and Function -- Adipose Tissue in Evolution -- Adipose Stem Cells and Adipogenesis -- Adipose Stem Cells and Adipogenesis -- Metabolism of White Adipose Tissue -- Bad Fat or Just More Fat? Murine Models of Metabolically Healthy Obesity -- The Aging Adipose Organ: Lipid Redistribution, Inflammation, and Cellular Senescence -- Adipokines: Leptin and Adiponectin in the Regulation of Inflammatory and Immune Responses -- Adipose Tissue Inflammation and Adipocyte Dysfunction in Obesity -- Adipose Tissue Inflammation -- Endoplasmic Reticulum Stress and Adipose Tissue Function -- Autophagy in White Adipose Tissue -- Obesity and Micronutrient Deficiencies -- Obesity -- Epidemiology of Obesity in Children -- Genetics of Obesity -- Epigenetics of Obesity -- Consequences of Rapid Weight Loss -- Adipose Tissue and Disease -- Human Lipodystrophy: An Update in Molecular Genetics and Possible Mechanisms of Fat Loss -- Adipose Tissue and Type 2 Diabetes Mellitus -- Adipokines in Nonalcoholic Fatty Liver Disease -- Obesity and Cardiovascular Disease -- Respiratory Diseases in Obesity -- Adiposity and Kidney Disease -- Obesity and Joint Disease -- Obesity and Colon and Postmenopausal Breast Cancer.
Format
e-Book
Location
Online
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Adult and Pediatric Neuromodulation

https://libcat.nshealth.ca/en/permalink/provcat42812
Jason P. Gilleran, Seth A. Alpert, editors. --Cham: Springer , c2018.
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This text reviews the anatomy and physiology of neuromodulation for treatment of various pathology of the human body, with specific emphasis on sacral neuromodulation for bladder and bowel dysfunction in the adult and pediatric populations. In addition to historical overview of the various methods of neuromodulation, present day applications will be discussed as well as possible future directions for use. Adult and Pediatric Neuromodulation will be of great value to medical professionals who ar…
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Other Authors
Gilleran, Jason P.
Alpert, Seth A.
Responsibility
Jason P. Gilleran, Seth A. Alpert, editors
Place of Publication
Cham
Publisher
Springer
Date of Publication
c2018
Physical Description
1 online resource (xiii, 243 p.) : 77 illus., 63 illus. in color
ISBN
9783319732664
9783319732657 (print ed.)
9783319732671 (print ed.)
Subjects (MeSH)
Central Nervous System - physiopathology
Electric Stimulation Therapy
Urinary Bladder Diseases - therapy
Urinary Incontinence - therapy
Fecal Incontinence - therapy
Specialty
Neurology
Abstract
This text reviews the anatomy and physiology of neuromodulation for treatment of various pathology of the human body, with specific emphasis on sacral neuromodulation for bladder and bowel dysfunction in the adult and pediatric populations. In addition to historical overview of the various methods of neuromodulation, present day applications will be discussed as well as possible future directions for use. Adult and Pediatric Neuromodulation will be of great value to medical professionals who are interested in the use of neuromodulation as a possible therapy option for their patients, particularly when other traditional or medical management options have failed. Each chapter is written by experts in the topic of various modalities of neuromodulation.
Contents
Part I: Adults -- Basic Neuroanatomy and Neurophyysiology of the Lower Urinary Tract -- Neuromodulation for Non-Urologic Chronic Pain -- Sacral Neuromodulation for Overactive Blader -- Neuromodulation for Non-Obstructive Urinary Retention -- Peripheral Nerve Evaluation -- Use of Electromyography (EMG) in Neuromodulation -- Pudendal Neuromodulation -- Neuromodulation for Chronic Pelvic Pain -- Sacral Neuromodulation for Fecal Incontinence -- Posterior Tibial Nerve Stimulation -- Management of Complications and Revisions of Sacral Neuromodulation -- CNS Non-invasive Brain Stimulation -- The Future of Neuromodulation -- Part II: Pediatrics -- Pediatric Posterior Tibial Nerve Stimulation -- Parasacral Transcutaneous Electrical Nerve Stimulation (TENS) in Pediatric Bladder Dysfunction -- Neuromodulation for Treatment of Pediatric Defecatory Disorders -- Pediatric Sacral Neuromodulation for Voiding Dysfunction.
Format
e-Book
Location
Online
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Adult learner, The : the definitive classic in adult education and human resource development

https://libcat.nshealth.ca/en/permalink/provcat52779
Knowles, Malcolm S. (6th ed.) --Amsterdam, Netherlands: Butterworth Heinemann , 2006.
Call Number
LC 5225 L42 K56 2006
Location
IWK Health Sciences Library
Call Number
LC 5225 L42 K56 2006
Author
Knowles, Malcolm S.
Other Authors
Holton, Elwood F.
Swanson, Richard A.
Edition
6th ed.
Place of Publication
Amsterdam, Netherlands
Publisher
Butterworth Heinemann
Date of Publication
2006
Physical Description
378 p.
ISBN
9.78E+12
Subjects (MeSH)
Learning
Program Development
Inservice Training
Education, Continuing
Format
Book
Location
IWK Health Sciences Library
Copies
1
Loan Period
2 weeks
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Adult T-cell Leukemia/Lymphoma

https://libcat.nshealth.ca/en/permalink/provcat41925
Toshiki Watanabe, Takuya Fukushima, editors. --Tokyo: Springer , 2017.
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This book provides essential information on the epidemiology, molecular and genetic features, anti-CCR4 antibody therapy and a nationwide study of transplantation on human T-leukemia virus type-I (HTLV-1) and adult T-cell leukemia/lymphoma (ATL). This rare but important disease has restricted endemic areas and distinct clinical features such as a high frequency of hypercalcemia, strong predisposition to infection and poor response to chemotherapy, aspects which set ATL apart from other types of…
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Other Authors
Watanabe, Toshiki
Fukushima, Takuya
Responsibility
Toshiki Watanabe, Takuya Fukushima, editors
Place of Publication
Tokyo
Publisher
Springer
Date of Publication
2017
Physical Description
1 online resource (viii, 169 pages) : 41 illus., 26 illus. in color
ISBN
9784431565239
9784431565215 (print ed.)
Subjects (MeSH)
Leukemia-Lymphoma, Adult T-Cell
Abstract
This book provides essential information on the epidemiology, molecular and genetic features, anti-CCR4 antibody therapy and a nationwide study of transplantation on human T-leukemia virus type-I (HTLV-1) and adult T-cell leukemia/lymphoma (ATL). This rare but important disease has restricted endemic areas and distinct clinical features such as a high frequency of hypercalcemia, strong predisposition to infection and poor response to chemotherapy, aspects which set ATL apart from other types of non-Hodgkin lymphoma. Given the small number of patients, enrollment in clinical trials has not been feasible, and establishing treatment standard has been difficult but new evidence, such as results of nationwide studies on transplantation, have shown new insights and potential treatments. Based on recent evidence, the book presents new treatment methods for ATL and infection prevention of HTLV-1, enabling clinicians, researchers and post-docs specializing in hematology and virology to gain a valuable overview of the disease.
Contents
1. Overview -- 2. Human T-Cell Leukemia Virus Type 1 (HTLV-1) -- 3. Epidemiology -- 4. Pathology -- 5. Immunophenotype -- 6. Leukemogenesis and Molecular Characteristics of Tumor Cells -- 7. Clinical Features of Adult T-cell Leukemia/Lymphoma (ATL) -- 8. Prognosis and Prognostic Index -- 9. Treatment of Indolent Adult T-cell Leukemia/Lymphoma (ATL) -- 10. Chemotherapy of Aggressive Adult T-cell Leukemia/Lymphoma (ATL) -- 11. Transplantation for Aggressive Adult T-Cell Leukemia/Lymphoma (ATL) -- 12. New Agents of Adult T-cell Leukemia/Lymphoma (ATL -- 13. Prevention of Human T-Cell Leukemia Virus Type 1 (HTLV-1) Mother-to-Child Transmission.
Format
e-Book
Location
Online
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Adult Vaccinations : Changing the Immunization Paradigm

https://libcat.nshealth.ca/en/permalink/provcat44121
Jean-Pierre Michel, Stefania Maggi, editors. --Cham: Springer , 2019.
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After introductory chapters devoted to the safe production and distribution of vaccines, the book addresses the question of adult vaccination in the framework of a life-course approach to vaccination. It presents the proceedings of multidisciplinary expert discussions with an excellent summary of the current state of knowledge on adult vaccination in various diseases, as well as an overview of the professionals involved and the obstacles to achieving greater vaccine uptake, and how these may be…
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Other Authors
Michel, Jean-Pierre
Maggi, Stefania
Responsibility
Jean-Pierre Michel, Stefania Maggi, editors
Place of Publication
Cham
Publisher
Springer
Date of Publication
2019
Physical Description
1 online resource (viii, 127 p.) : 1 illus. in color
Series
Practical Issues in Geriatrics
Series Title
Practical issues in geriatrics
ISBN
9783030051594
9783030051587 (Print ed.)
9783030051600 (Print ed.)
ISSN
2509-6060
Subjects (MeSH)
Adult
Aging - immunology
Immunization
Vaccination
Vaccines
Specialty
Public Health
Abstract
After introductory chapters devoted to the safe production and distribution of vaccines, the book addresses the question of adult vaccination in the framework of a life-course approach to vaccination. It presents the proceedings of multidisciplinary expert discussions with an excellent summary of the current state of knowledge on adult vaccination in various diseases, as well as an overview of the professionals involved and the obstacles to achieving greater vaccine uptake, and how these may be addressed. The book systematically discusses the major vaccine-preventable diseases, as well as regulatory issues in vaccine provision, and presents the results of an expert meeting designed to identify the obstacles to vaccination, and solutions for addressing these barriers. It goes on to extend the discussion beyond the traditional boundaries of human health to encompass the “one health” concept. The book is intended for all those with an interest in vaccination, including physicians (from a wide range of disciplines including geriatrics/gerontology, infectious diseases, pediatrics, internal medicine, and other non-organ specialties), other healthcare professionals, pharmacists, representatives of the pharmaceutical industry and regulatory bodies (EMEA, national authorities), policymakers, the media and the general public.
Contents
Foreword. Adult vaccinations: essential but too often forgotten -- 1. Complexity of vaccine manufacture and supply -- 2. Administration of vaccines: current process, new technologies, adjuvants -- 3. How can the European Medicines Agency support an appropriate strategy of adult vaccination? -- 4. Public health impact of adult vaccine-preventable diseases on performance, disability, mortality and health care costs in Europe -- 5. Outcomes after HPV vaccination -- 6. Impact of nutrition on adult vaccination efficacy -- 7. Profiling vaccines for an immunosenescent and multimorbid population -- 8. Comprehensive geriatric assessment in infectious diseases -- 9. Etiology of respiratory tract infections in adults in Europe: current knowledge and knowledge gaps -- 10. European flu vaccine regulations and their impacts in community-dwelling adults -- 11. Vaccination against pneumococcal disease in the European Union, with particular focus on Germany -- 12. Direct and indirect benefits of a comprehensive approach to vaccinating adults with influenza and pneumococcal vaccines, especially in patients with chronic diseases -- 13. Vaccination of health care professionals and protection of hospitalized adults and nursing home residents -- 14. Ongoing threats for older Europeans: Diphtheria, Pertussis and Tetanus -- 15. Herpes Zoster vaccination: a vaccine to prevent pain -- 16. Gastroenteritis burden in the adult community: prospects for vaccines -- 17. Travel vaccination -- 18. Integrating the veterinarian scientist to the one-health concept -- 19. Stressing the importance of adult immunization: suggestions for how to change the paradigm -- 20. How can we integrate life course vaccination into the new WHO definition of “Healthy Ageing”?.
Format
e-Book
Location
Online
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Advances in Nutrition and Cancer

https://libcat.nshealth.ca/en/permalink/provcat39632
Vincenzo Zappia, Salvatore Panico, Gian Luigi Russo, Alfredo Budillon, Fulvio Della Ragione, editors. --Berlin, Heidelberg: Springer , c2014.
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This book comprises proceedings from the Third International Conference on Advances in Nutrition and Cancer, held in Naples in May 2012. This highly multidisciplinary meeting analyzed "nutrition and cancer" from different perspectives and on the basis of distinct and up-to-date experimental approaches. Knowledge on the relation between lifestyle, diet, and cancer is explored in a number of contributions, and the role of dietary intervention in cancer patients is discussed. Issues of vital inter…
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Other Authors
Zappia, Vincenzo
Panico, Salvatore
Russo, Gian Luigi
Budillon, Alfredo
Della Ragione, Fulvio
Other Authors
International Conference on Advances in Nutrition and Cancer (3rd : 2012 : Naples, Italy)
Responsibility
Vincenzo Zappia, Salvatore Panico, Gian Luigi Russo, Alfredo Budillon, Fulvio Della Ragione, editors
Place of Publication
Berlin, Heidelberg
Publisher
Springer
Date of Publication
c2014
Physical Description
1 online resource (xiv, 460 p. : 59 illus., 34 illus. in color)
Series Vol.
159
Series Title
Cancer treatment and research
ISBN
9783642380075
9783642380068 (print ed.)
ISSN
0927-3042
Subjects (MeSH)
Feeding Behavior
Neoplasms - diet therapy
Neoplasms - etiology
Neoplasms - prevention & control
Abstract
This book comprises proceedings from the Third International Conference on Advances in Nutrition and Cancer, held in Naples in May 2012. This highly multidisciplinary meeting analyzed "nutrition and cancer" from different perspectives and on the basis of distinct and up-to-date experimental approaches. Knowledge on the relation between lifestyle, diet, and cancer is explored in a number of contributions, and the role of dietary intervention in cancer patients is discussed. Issues of vital interest to the research community, such as epidemiological and experimental oncology (genetics, epigenetics, and the mechanisms of action of natural compounds in the diet), receive detailed consideration. A further key topic is the emerging molecular technologies (the "omics") that can cast light on the interplay between nutrition and human malignancies. Chapters take the form of reviews that include sections presenting expert opinions. Advances in Nutrition and Cancer will be an invaluable source of topical information for all researchers and clinicians with an interest in this field.
Contents
Part I: Life Style, Diet and Cancer -- The role of metabolic carcinogenesis in cancer causation and prevention: evidence from the European prospective investigation into cancer and nutrition -- Obesity, energy balance and cancer: a mechanistic perspective -- Fruits and vegetables. Updating the epidemiologic evidence for the WCRF-AICR lifestyle recommendations for cancer prevention -- The diet as a cause of human prostate cancer -- Mediterranean dietary pattern and chronic diseases -- Dietary salt intake and risk of gastric cancer -- Alcoholic beverages and carbonated soft drinks: consumption and gastrointestinal cancer risks -- Part II: Natural Dietary Molecules -- Anti-inflammatory and anti-cancer drugs from nature -- Selenium and cancer: a story that should not be forgotten--Insights from genomics -- Resveratrol: from basic studies to bedside -- Quercetin: a pleiotropic kinase inhibitor against cancer -- Sulforaphane as a promising molecule for fighting cancer -- Part III: Genetics and Epigenetics -- Functions, aberrations and advances for chromatin modulation in cancer -- Epigenetics and epidemiology: models of study and examples -- Dietary epigenetics in cancer and aging -- Breast cancer and the importance of early life nutrition -- Part IV: Olive Oil in Cancer Prevention -- Olive oil and other dietary lipids in breast cancer -- A holistic approach to study the effects of natural antioxidants on inflammation and liver cancer -- Extra virgin olive oil: from composition to "molecular gastronomy" -- Part V: Life Style Prevention of Cancer -- Life style prevention of cancer recurrence: the yin and the yang -- Part VI: Emerging Breakthroughs -- New perspective for an old antidiabetic drug: metformin as anticancer agent -- Gut microbes, diet and cancer -- Inflammatory angiogenesis and the tumor microenvironment as targets for cancer therapy and prevention -- Nutriomes and personalised nutrition for DNA damage prevention, telomere integrity maintenance and cancer growth control -- Novel approaches in melanoma prevention and therapy -- Concluding remarks.
Format
e-Book
Publication Type
Congress
Location
Online
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Advances in Vision Research. Volume I, Genetic Eye Research in Asia and the Pacific

https://libcat.nshealth.ca/en/permalink/provcat41924
Gyan Prakash, Takeshi Iwata, editors. --Tokyo: Springer , 2017.
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This book presents the state of the art in genetic eye research in Asia and the Pacific. Though there has been an explosion of information on genetic eye research in western countries, more than sixty percent of the human genes involved in eye diseases in the Asian and Pacific population remain unknown. However, new efforts and a new awareness have sparked important discussions on the subject, and new plans are being implemented to discover the genes responsible for many eye diseases in the pop…
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Other Authors
Prakash, Gyan
Iwata, Takeshi
Responsibility
Gyan Prakash, Takeshi Iwata, editors
Alternate Title
Genetic Eye Research in Asia and the Pacific
Place of Publication
Tokyo
Publisher
Springer
Date of Publication
2017
Physical Description
1 online resource (xv, 523 pages) : 71 illus., 55 illus. in color
Series Title
Essentials in ophthalmology
ISBN
9784431565116
9784431565093 (print ed.)
ISSN
1612-3212
Subjects (MeSH)
Eye diseases - genetics
Biomedical Research
Other Subjects
Asia
Abstract
This book presents the state of the art in genetic eye research in Asia and the Pacific. Though there has been an explosion of information on genetic eye research in western countries, more than sixty percent of the human genes involved in eye diseases in the Asian and Pacific population remain unknown. However, new efforts and a new awareness have sparked important discussions on the subject, and new plans are being implemented to discover the genes responsible for many eye diseases in the population. The book reviews the latest findings; its content ranges from genetic aspects of human migration to DNA sequence analysis, genome-wide association analysis, and disease phenotypes. The efforts of the Asian Eye Genetic Consortium (AEGC) are also discussed. The book's editors have been instrumental in developing strategies for discovering the new Asian genes involved in many eye diseases. All chapters were written by leading researchers working on Asian eye genetics from the fields of Human Genetics, Ophthalmology, Molecular Biology, Biochemistry, Sensory Sciences, and Clinical Research. Advances in Vision Research, Volume I will prove to be a major resource for all researchers, clinicians, clinical researchers, and allied eye health professionals with an interest in eye diseases among the Asian population.
Contents
1. Foundation of Asian Eye Genetics Consortium (AEGC) -- 2. Japan consortium for whole exome analysis of hereditary retinal diseases -- 3. Whole-genome sequencing in genetic eye diseases in China -- 4. Targeted exome sequencing in Japanese patients with Retinitis Pigmentosa -- 5. Genetic Epidemiology of Congenital Cataracts and Autosomal Recessive Retinal Degenerations in Pakistan -- 6. Genetics of Cataract in Asia -- 7. Genetic analysis of families with retinal dystrophies -- 8. Whole genome sequencing in patients with Retinitis Pigmentosa -- 9. Retinitis pigmentosa in Korean patients -- 10. Retinitis pigmentosa in Chinese population -- 11. Retinitis Pigmentosa in Japanese Population -- 12. Cone Dysfunction Syndrome in Japanese Population -- 13. Leber Congenital Amaurosis/Early-Onset Retinal Dystrophy in Japanese Population -- 14. Paradigm of Susceptibility genes in AMD and PCV -- 15. Genetics and Pathology of Inflammatory Components on AMD -- 16. Genome wide association study of age-related eye diseases in Chinese population -- 17. Clinical Genetics of Retinoblastoma: An Asian Perspective -- 18. Molecular and Clinical Genetics of Retinoblastoma -- 19. Current research Perspectives in Understanding Diabetic Retinopathy -- 20. Genome-wide association studies of glaucoma -- 21. Genetic Complexity of Primary Angle Closure Glaucoma in Asians -- 22. Genotype-phenotype correlation for POAG in the Middle East Khaled Abu-Amero (Saudi Arabia), Alta-- 23. Corneal Dystrophies in India -- 24. Genetics of Corneal Endothelial Dystrophies: An Asian Perspective -- 25. Keratoconus in Asia -- 26. Genetics of Pediatric Eye Diseases and Strabismus in Asia -- 27. Keratoconus: Globally and in the Middle East; Epidemiology, Genetics and future Research -- 28. Genetics of Myopia -- 29. Ocular Implications of Gaucher Disease -- 30. Genetic background of Uveitis in Chinese population -- 31. Usher Syndrome in Chinese and Japanese Population -- 32. Homozygosity Mapping for Autosomal Recessive Ocular Diseases -- 33. Tools of Genetic Eye Research and Need for Clinical Research Collaborations -- 34. Eye Genetics: The Road Ahead to Quality Standards -- 35. Genetic Counselling in Asia -- 36. Epigenetic study in Asian Eye Diseases -- 37. Unique Asian Patients Population: An Opportunity for Drug Development -- 38. A Perspective: How can gene therapeutics help address ophthalmic health issues in Asia?
Format
e-Book
Location
Online
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