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Anesthesiology : Clinical Case Reviews

https://libcat.nshealth.ca/en/permalink/provcat41640
Linda S. Aglio, Richard D. Urman, editors. --Cham: Springer , 2017.
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Holdings
Cape Breton Regional: 2005 - 2006.
Halifax Infirmary: v. 70, 1989 - v. 81, 1994.
Location
Online
Divided into twelve sections that cover the entirety of anesthetic practice, this is a case-based, comprehensive review of anesthesiology that covers the basics of anesthetic management and reflects all new guidelines and recently developed standards of care. Each chapter of Anesthesiology: Clinical Case Reviews begins with a specific clinical problem or a clinical case scenario, followed by concise discussions of preoperative assessment, intraoperative management, and postoperative pain manage…
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Other Authors
Aglio, Linda S
Urman, Richard D
Responsibility
Linda S. Aglio, Richard D. Urman, editors
Place of Publication
Cham
Publisher
Springer
Date of Publication
2017
Holdings
Cape Breton Regional: 2005 - 2006.
Halifax Infirmary: v. 70, 1989 - v. 81, 1994.
Physical Description
1 online resource (xv, 493 pages) : 19 illus., 13 illus. in color
ISBN
9783319501413
9783319501390 (print ed.)
ISSN
0003-3022
Subjects (MeSH)
Anesthesia
Abstract
Divided into twelve sections that cover the entirety of anesthetic practice, this is a case-based, comprehensive review of anesthesiology that covers the basics of anesthetic management and reflects all new guidelines and recently developed standards of care. Each chapter of Anesthesiology: Clinical Case Reviews begins with a specific clinical problem or a clinical case scenario, followed by concise discussions of preoperative assessment, intraoperative management, and postoperative pain management. In addition to residents and fellows, this book is written for practicing anesthesiologists, student nurse anesthetists, and certified registered nurse anesthetists (CRNAs).
Contents
Part I: Cardiovascular System -- 1. Coronary Artery Disease -- 2. Myocardial Infarction -- 3. Heart Failure -- 4. Hypothermia -- 5. Anesthetic Considerations in Patients with Valvular Heart Disease -- 6. Mitral Stenosis -- 7. Eisenmenger Syndrome -- 8. Subacute Bacterial Endocarditis Prophylaxis -- 9. Hypertrophic Cardiomyopathy (HCM) -- 10. Pacemakers and Implantable Cardioverter Defibrillators -- 11. Pericardial Tamponade -- 12. Non-cardiac Surgery after Heart Transplantation -- 13. Anesthesia for Coronary Artery Bypass Graft (CABG) -- Part II: The Respiratory System -- 14. One-Lung Ventilation -- Part III: The Central Nervous System -- 15. Anesthesia Management for Posterior Fossa Craniotomy -- 16. Intracranial Aneurysm -- 17. Carotid Endarterectomy -- 18. Spine Surgery and Intraoperative Monitoring -- 19. Transsphenoidal Hypophysectomy -- Part IV: The Neuromuscular System -- 20. Depolarizing Neuromuscular Blocking Agents -- 21. Non-depolarizing Neuromuscular Blocking Agents -- 22. Myasthenia Gravis -- 23. Malignant Hyperthermia -- Part V: The Endocrine System -- 24. Diabetes Mellitus -- 25. Thyrotoxicosis -- 26. Pheochromocytoma -- Part VI: The Abdomen -- 27. The Full Stomach -- 28. Anesthesia for Liver Transplantation -- 29. Anesthesia for Open Repair of Abdominal Aortic Aneurysm -- 30. Anesthesia for Endovascular Aortic Aneurysm Repair (EVAR) -- 31. Morbid Obesity -- 32. Laparoscopy -- 33. Carcinoid Disease -- 34. Kidney Transplantation -- Part VII: Eye, Ear, and Throat Surgery -- 35. Open Eye Injury -- 36. Anesthesia for Tympanomastoidectomy -- 37. The Difficult Airway -- 38. Pediatric Tonsillectomy and Adenoidectomy -- 39. Laser Surgery of the Airway -- Part VIII: Blood/Hematologic System -- 40. Transfusion Reactions -- 41. Intraoperative Coagulopathies -- 42. Hemophilia -- 43. Sickle Cell Disease: Anesthetic Management -- Part IX: Orthopedic Surgery -- 44. Total Hip Replacement -- 45. Local Anesthetics -- 46. Spinal Anesthesia -- 47. Brachial Plexus Block -- Part X: Obstetrics -- 48. Labor and Delivery -- 49. Preeclampsia -- 50. Abruptio Placenta and Placenta Previa -- 51. Nonobstetric Surgery During Pregnancy -- Part XI: Pediatrics -- 52. Neonatal Resuscitation -- 53. Gastroschisis and Omphalocele -- 54. Congenital Diaphragmatic Hernia -- 55. Pyloric Stenosis -- 56. Tracheoesophageal Fistula -- 57. Congenital Heart Disease: Atrioventricular Septal Defects -- 58. Premature Infant -- Part XII: Critical Care -- 59. Trauma Anesthesia -- 60. Burns.
Format
e-Book
Publication Type
Case Reports
Location
Online
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Basic radiotherapy physics and biology

https://libcat.nshealth.ca/en/permalink/provcat33462
David S. Chang, Foster D. Lasley, Indra J. Das, Marc S. Mendonca, Joseph R. Dynlacht. --New York: Springer , c2014.
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Location
Online
This book is a concise and well-illustrated review of the physics and biology of radiation therapy intended for radiation oncology residents, radiation therapists, dosimetrists, and physicists. It presents topics that are included on the Radiation Therapy Physics and Biology examinations and is designed with the intent of presenting information in an easily digestible format with maximum retention in mind. The inclusion of mnemonics, rules of thumb, and reader-friendly illustrations throughout …
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Other Authors
Chang, David S
Responsibility
David S. Chang, Foster D. Lasley, Indra J. Das, Marc S. Mendonca, Joseph R. Dynlacht
Place of Publication
New York
Publisher
Springer
Date of Publication
c2014
Physical Description
1 online resource (xix, 348 pages)
ISBN
9783319068411 (electronic bk.)
9783319068404
Subjects (MeSH)
Health Physics
Radiometry
Radiotherapy
Subjects (LCSH)
Radiotherapy
Diagnostic Radiology
Abstract
This book is a concise and well-illustrated review of the physics and biology of radiation therapy intended for radiation oncology residents, radiation therapists, dosimetrists, and physicists. It presents topics that are included on the Radiation Therapy Physics and Biology examinations and is designed with the intent of presenting information in an easily digestible format with maximum retention in mind. The inclusion of mnemonics, rules of thumb, and reader-friendly illustrations throughout the book help to make difficult concepts easier to grasp. Basic Radiotherapy Physics and Biology is a valuable reference for students and prospective students in every discipline of radiation oncology.
Contents
Part I. Radiation Therapy Physics -- 1. Atomic and Nuclear Structure -- 2. Radioactive Decay -- 3. Production and Properties of Radiation -- 4. Interactions of Electromagnetic Radiation with Matter -- 5. Interactions of Particulate Radiation with Matter -- 6. Quantification and Measurement of Dose -- 7. Characteristics of Photon Beams -- 8. Dosimetry of Photon Beams in Water -- 9. Dosimetry of Photon Beams in a Patient -- 10. Dosimetry of Electron Beams -- 11. Physics and Dosimetry of Brachytherapy -- 12. Advanced Treatment Planning for EBRT -- 13. Linac Quality Assurance -- 14. Radiation Protection and Safety -- 15. Quality Management Program -- 16. Special Topics: Hyperthermia and Computers -- Part II. Radiation Therapy Biology -- 17. Molecular Biology and Signaling -- 18. Cancer Genetic and Molecular Characteristics -- 19. Molecular Mechanisms of DNA Damage and Repair -- 20. Cell Death and Survival Assays -- 21. Fractionated Radiation Survival Models -- 22. Oxygen Effect, Relative Biological Effectiveness and Linear Energy Transfer -- 23. Tumor Micro-environment -- 24. Cell and Tissue Kinetics -- 25. Acute Effects of Total Body Irradiation (TBI) -- 26. Normal Tissue Radiation Responses -- 27. Therapeutic Ratio -- 28. Combined Modality Therapy -- 29. Biology of Brachytherapy, Particle Therapy, and Alternative Radiation Modalities -- 30. Hyperthermia -- 31. Carcinogenesis and Heritable Effects -- 32. Radiation Effects in the Embryo and Fetus -- Appendix A. Glossary of Terms and Physical Constants -- Appendix B. List of Radionuclides for Radiotherapy and Imaging.
Format
e-Book
Location
Online
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Breast Cancer : Innovations in Research and Management

https://libcat.nshealth.ca/en/permalink/provcat41607
Umberto Veronesi, Aron Goldhirsch, editors-in-chief ; Paolo Veronesi, Oreste Davide Gentilini, Maria Cristina Leonardi, editors. --Cham: Springer , 2017.
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Location
Online
This book provides the reader with up-to-date information on important advances in the understanding of breast cancer and innovative approaches to its management. Current and emerging perspectives on genetics, biology, and prevention are first discussed in depth, and individual sections are then devoted to pathology, imaging, oncological surgery, plastic and reconstructive surgery, medical oncology, and radiotherapy. In each case the focus is on the most recent progress and/or state of the art …
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Other Authors
Veronesi, Umberto
Goldhirsch, Aron
Veronesi, Paolo
Gentilini, Oreste Davide
Leonardi, Maria Cristina
Responsibility
Umberto Veronesi, Aron Goldhirsch, editors-in-chief ; Paolo Veronesi, Oreste Davide Gentilini, Maria Cristina Leonardi, editors
Place of Publication
Cham
Publisher
Springer
Date of Publication
2017
Physical Description
1 online resource (xiv, 928 pages) : 296 illus., 236 illus. in color
ISBN
9783319488486
9783319488462 (print ed.)
Subjects (MeSH)
Breast Neoplasms - pathology
Breast Neoplasms - therapy
Abstract
This book provides the reader with up-to-date information on important advances in the understanding of breast cancer and innovative approaches to its management. Current and emerging perspectives on genetics, biology, and prevention are first discussed in depth, and individual sections are then devoted to pathology, imaging, oncological surgery, plastic and reconstructive surgery, medical oncology, and radiotherapy. In each case the focus is on the most recent progress and/or state of the art therapies and techniques. Further topics to receive detailed consideration include particular conditions requiring multidisciplinary approaches, the investigation of new drugs and immunological agents, lifestyle and psychological aspects, and biostatistics and informatics. The book will be an excellent reference for practitioners, interns and residents in medical oncology, oncologic surgery, radiotherapy, pathology, and human genetics, researchers, and advanced medical students.
Contents
Part I: An Integrated view of Breast Cancer Biology -- Fundamental pathways in breast cancer 1: signaling from the membrane -- Fundamental pathways in breast cancer 2: maintenance of genomic stability -- Fundamental pathways in breast cancer 3: estrogen biology -- Fundamental pathways in breast cancer 4: maintenance of epigenomic stability and the role of stem cells -- Breast cancer microenvironment and the metastatic process -- Mouse models of breast cancer -- Human mammary tumor virus proteins in human breast cancer cells -- Part II: Epidemiology, Genetics and Prevention -- Epidemiology, life style and environment -- Genetic predisposition -- Chemoprevention -- Surgical prevention -- Part III Pathology: Standard and Molecular Diagnostics -- Premalignant lesions -- Prognostic and predictive role of genetic signatures -- Adding molecular information to immunohistochemistry -- Special types of breast cancer and nonepithelial tumors -- Pathology after neoadjuvant treatments -- Breast cancer genomics -- Pathology report 2015 -- Part IV: Imaging -- Radiological screening of breast cancer. Evolution -- Innovation of radiological means for breast cancer -- Nuclear medicine in the clinical management (ROLL, SNB and PET) -- One-step systemic staging for patients with breast cancer -- Imaging after breast surgery -- Integrated breast biopsy for best radiological diagnosis of breast cancer -- Part V: Oncological Surgery -- Conservative surgery -- Conservative mastectomies -- Surgical treatment of reappearance of breast cancer -- Management of the axilla -- Management of intraepithelial disease -- Surgery after neoadjuvant therapies -- Surgery of primary tumor in stage IV breast cancers -- Local therapy for breast cancer in malignant lymphoma survivors -- Surgery of metastases -- Part VI: Plastic and Reconstructive Surgery -- Oncoplastic surgery -- Delayed breast reconstruction -- Immediate breast reconstruction direct-to-implant -- Breast reconstruction with tissue expanders and definitive implant replacement -- Breast reconstruction with pedicled flaps -- Breast reconstruction with free flaps -- Contralateral breast management -- Fat grafting in breast reconstruction -- Breast reconstruction with biological and nonbiological meshes -- How to manage complications in breast reconstruction -- Part VII: Medical Oncology -- Adjuvant systemic therapies by subtypes: guidelines -- Primary systemic therapies: guidelines -- Treatment of advanced disease: guidelines -- Endocrine therapies in the adjuvant and advanced disease settings -- Chemotherapy regimens in the adjuvant and advanced disease settings -- Anti-HER2 therapies in the adjuvant and advanced disease settings -- Systemic therapy with bisphosphonates and anti-RANK-L agents -- Systemic treatment for specific medical situations -- Part VIII: Radiotherapy -- Conceptual basis and principles of radiation oncology -- Whole breast radiation following breast-conserving surgery in invasive cancer -- Whole breast radiation following breast-conserving surgery in noninvasive cancer -- Post-mastectomy radiotherapy -- Integration of radiotherapy with systemic therapies -- Partial breast irradiation -- Intraoperative radiotherapy ELIOT -- Radiotherapy for metastatic lesions -- Part IX: Special Conditions Requiring Multidisciplinary Approaches -- Emergencies in breast cancer -- Breast cancer during pregnancy -- Fertility issues in patients with newly diagnosed breast cancer -- Sexual functions and breast cancer -- Male breast cancer -- Inflammatory breast cancer -- Treatment of CNS involvement -- Treatment of skeletal disease -- Follow-up of patients with breast cancer -- Part X: Investigating New Drugs and Immunological Agents in Breast Cancer -- Targeting immune-checkpoint -- Targeting PIK3CA/AKT/mTOR -- Targeting genome instability and DNA repair -- Targeting CDK4/6 pathway -- Targeting FGFR pathway -- Integrating next generation sequencing data in trial design -- Part XI: Investigational and Miscellaneous Approaches -- Lifestyle and breast cancer -- Psychological support -- HIFU and radiofrequency as alternatives to surgery -- Hyperthermia with RT and with systemic therapies -- Electro-chemotherapy -- Circulating miRNA in early diagnosis -- Relevance of stem cells -- Part XII Biostatistics and Bioinformatics -- Subgroup analyses and information from clinical trials on breast cancer -- The methodology of meta analyses and its potential contribution to patient care -- Modern biostatistics for accelerated data acquisition for new drugs -- Bioinformatics for clinical use in breast cancer -- Efficacy endpoints in breast cancer studies.
Format
e-Book
Location
Online
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Cancer Management in Man : Chemotherapy, Biological Therapy, Hyperthermia and Supporting Measures

https://libcat.nshealth.ca/en/permalink/provcat28897
edited by Boris R. Minev. --Dordrecht ; New York: Springer Science+Business Media , c2011.
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Location
Online
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Author
Minev, Boris R
Responsibility
edited by Boris R. Minev
Place of Publication
Dordrecht ; New York
Publisher
Springer Science+Business Media
Date of Publication
c2011
Series Vol.
13
Series Title
Cancer growth and progression
ISBN
9789048197040
Subjects (MeSH)
Antineoplastic Agents - therapeutic use
Neoplasms - drug therapy
Neoplasms - therapy
Subjects (LCSH)
Oncology
Format
e-Book
Location
Online
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Cancer Regional Therapy : HAI, HIPEC, HILP, ILI, PIPAC and Beyond

https://libcat.nshealth.ca/en/permalink/provcat45119
Yuman Fong, T. Clark Gamblin, Ernest S. Han, Byrne Lee, Jonathan S. Zager, editors. --Cham: Springer , c2020.
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Location
Online
This book is a state-of-the-art overview of cancer regional therapy (CRT) for the surgeons and interventional radiologists active in CRT development and research. The goals of this book are 1) to review the theory and practice of cancer regional therapies including pharmacology, devices, techniques, and workflow, 2) illustrate the most common procedures performed in the interventional and operating rooms, and 3) discuss data supporting use of CRT. This is meant to be a definitive text on the th…
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Other Authors
Fong, Yuman
Gamblin, T. Clark
Han, Ernest S.
Lee, Byrne
Zager, Jonathan S.
Responsibility
Yuman Fong, T. Clark Gamblin, Ernest S. Han, Byrne Lee, Jonathan S. Zager, editors
Place of Publication
Cham
Publisher
Springer
Date of Publication
c2020
Physical Description
1 online resource (xxvi, 488 p.) : 86 illus., 64 illus. in color
ISBN
9783030288914
9783030288907 (Print ed.)
9783030288921 (Print ed.)
9783030288938 (Print ed.)
Subjects (MeSH)
Chemotherapy, Cancer, Regional Perfusion
Neoplasm Invasiveness - prevention & control
Neoplasm Metastasis
Neoplasms - therapy
Specialty
Medical Oncology
Abstract
This book is a state-of-the-art overview of cancer regional therapy (CRT) for the surgeons and interventional radiologists active in CRT development and research. The goals of this book are 1) to review the theory and practice of cancer regional therapies including pharmacology, devices, techniques, and workflow, 2) illustrate the most common procedures performed in the interventional and operating rooms, and 3) discuss data supporting use of CRT. This is meant to be a definitive text on the theory and practice of CRT. It begins with a summary of the history, technical principles that underlie regional therapy. The following parts discuss current data and practice in peritoneal, liver, limb, pleural and other sites. Included in the practice are considerations of workflow and financial issues revolving around CRT. Novel techniques and therapies under investigation are presented to inform the direction of the field. Cancer Regional Therapy summarizes the history, current technology, common procedures, and future prospects in this field and includes procedures from many surgical and interventional radiologic disciplines.
Contents
Part I. Background -- 1. The Basis of Regional Therapy, Pharmacology, Hyperthermia, and Drug Resistance -- 2. Novel Biological Therapies with Direct Application to the Peritoneal Cavity -- 3. Y-90 Radiomicrosphere Therapy: Principles and Clinical Use in Colorectal Cancer Liver Metastases -- 4. Principles of Percutaneous Ablation in the Liver -- 5. Regional Gene Therapy for Cancer -- Part II. Peritoneal Regional Therapy for Cancer -- 6. Historical Perspective for Regional Peritoneal Therapy: HIPEC, EPIC, and Port-Based Therapy -- 7. Rationale Behind HIPEC/Molecular and Genetic Considerations in HIPEC -- 8 .Data for HIPEC for Pseudomyxoma Peritonei/Tumors of the Appendix -- 9. Data for HIPEC in Colorectal Cancer (T4 Lesions and Metastases) -- 10. Role of Hyperthermic Intraperitoneal Chemotherapy (HIPEC) in the Treatment of Peritoneal Metastasis of Gastric Cancer -- 11. Regional Therapy for the Treatment of Ovarian Cancer: HIPEC and Intraperitoneal Chemotherapy -- 12. Mesothelioma and Miscellaneous Disease Processes -- Part III. Perioperative Considerations for HIPEC -- 13. Anesthetic Considerations for Regional Therapies -- 14. Postoperative Management of Patients Undergoing Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy -- 15. Complications of Cytoreductive Surgery and HIPEC -- 16. Liver Resection and HIPEC -- 17. Peritoneal Perfusion Techniques -- 18. Operative Pearls for Cytoreduction of the Difficult Abdomen and Pelvis -- 19. Novel Techniques and the Future of HIPEC (Immunotherapy, Viral Therapy) -- 20. Pressurized Intraperitoneal Aerosol Chemotherapy (PIPAC) -- Part IV. Liver Infusional and Perfusional Therapies -- 21. The History of Isolated Hepatic Perfusion for Liver Metastases and Current Indications for Use -- 22. Pump-Based Hepatic Arterial Infusional Therapy -- 23. Percutaneous Transcatheter Particle Therapies -- 24. Hepatic Perfusion: Surgical and Catheter -- 25. Percutaneous and Port Delivered Arterial Infusional Therapy for Liver Tumors -- 26. Regional Therapies in Hepatocellular Carcinoma and Cholangiocarcinoma -- 27. Regional Therapies for Hepatic Melanoma Metastases -- 28. Complications of Intra-Arterial Regional Liver Therapy -- Part V. Limb Infusional and Perfusional Therapies -- 29. Infusion Technique -- 30. Hyperthermic Isolated Limb Perfusion for Melanoma -- 31. Isolated Limb Perfusion and Infusion in the Management of In-Transit Melanoma of the Extremities: Modern Data Affecting Practice -- 32. Trial Data for Sarcoma -- Part VI. Other Regional Therapies -- 33. Regional Therapy of Bladder Tumors -- 34. Delivery of Antineoplastic Therapeutics to the Central Nervous System -- 35. Intralesional Therapies: Oncolytic Viral Therapies, Immunostimulants -- 36. Ongoing Clinical Trials and Rationale in Regional and Oligometastatic Disease -- 37. Radiation Therapy.
Format
e-Book
Location
Online
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Clinical Manual of Fever in Children

https://libcat.nshealth.ca/en/permalink/provcat43817
A. Sahib El-Radhi, editor. (Second edition) --Cham: Springer , 2018.
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Online
The book covers all the different types of fever and its possible complications discussed the management of fever with guidelines on antipyretics and their side effects and differential diagnosis of fever, with problem-setting and solving as a case presentation. The second edition of this well-received book has been fully updated to include exciting new information of the pathogenesis of fever, including functions of interleukin and all the latest guidelines from NICE and Cochrane Library, as w…
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Other Authors
El-Radhi, A. Sahib
Responsibility
A. Sahib El-Radhi, editor
Edition
Second edition
Place of Publication
Cham
Publisher
Springer
Date of Publication
2018.
Physical Description
1 online resource (xvi, 315 p. : 26 illus.)
ISBN
9783319923369
9783319923352 (Print ed.)
9783319923376 (Print ed.)
Subjects (MeSH)
Child
Fever - therapy
Specialty
Pediatrics
Abstract
The book covers all the different types of fever and its possible complications discussed the management of fever with guidelines on antipyretics and their side effects and differential diagnosis of fever, with problem-setting and solving as a case presentation. The second edition of this well-received book has been fully updated to include exciting new information of the pathogenesis of fever, including functions of interleukin and all the latest guidelines from NICE and Cochrane Library, as well as all the most up-to-date information and guidelines on febrile seizures. This reader-friendly reference on the disorders of body temperature in children covers the entire spectrum of subjects related to fever. It gives an overview of the best treatment options in order to achieve the best results. Containing a core message at the start of each chapter and with and a reader-friendly format this is an indispensable guide for paediatr icians, family doctors and other professionals who are regularly consulted because of febrile children.
Contents
1. Fever -- 2. Hyperthermia -- 3. Pathogenesis of Fever -- 4. Measurement of Body Temperature -- 5. Fever in Common Infectious Diseases -- 6. Fever in Non-infectious Diseases -- 7. Febrile Seizures -- 8. Hypothermia -- 9. Is Fever Beneficial? -- 10. Management of Fever (Antipyretics) -- 11. Fever and Complementary and Alternative Medicine -- 12. Differential Diagnosis (DD) of Febrile Diseases -- 13. History of Fever - 14. Glossary of the Term Fever.
Format
e-Book
Location
Online
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Consults in Obstetric Anesthesiology

https://libcat.nshealth.ca/en/permalink/provcat42685
Suzanne K.W. Mankowitz. editor. --Cham: Springer , c2018.
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Online
This text addresses the need for a book specifically aimed at obstetric anesthesia and covers topics such as pulmonary, cardiac renal, hepatic, hematologic, neurologic, endocrine and other diseases. The real anesthetic challenge arises when patients present to Labor and Delivery with unusual or complicated medical problems and, in recent years, a few of the larger institutions have developed an Obstetric Anesthesiology Consultation Service to prepare for the management of these patients. While …
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Other Authors
Mankowitz, Suzanne K.W.
Responsibility
Suzanne K.W. Mankowitz. editor
Place of Publication
Cham
Publisher
Springer
Date of Publication
c2018
Physical Description
1 online resource (xxiv, 699 p.) : 77 illus., 48 illus. in color
ISBN
9783319596808
9783319596792 (print ed.)
9783319596815 (print ed.)
Subjects (MeSH)
Anesthesia, Obstetrical
Delivery, Obstetric
Pregnancy Complications - prevention & control
Pregnancy, High-Risk
Preoperative Care
Referral and Consultation
Specialty
Anesthesiology
Obstetrics
Abstract
This text addresses the need for a book specifically aimed at obstetric anesthesia and covers topics such as pulmonary, cardiac renal, hepatic, hematologic, neurologic, endocrine and other diseases. The real anesthetic challenge arises when patients present to Labor and Delivery with unusual or complicated medical problems and, in recent years, a few of the larger institutions have developed an Obstetric Anesthesiology Consultation Service to prepare for the management of these patients. While most pregnant women who present to Labor and Delivery require anesthetic intervention, they typically meet the anesthesiologist for the first time in labor. Since the majority of laboring women are healthy without significant comorbidities, this does not present much of a challenge to the anesthesiologist and the anesthetic management tends to be straight-forward with favorable outcomes. However, using this new model, the anesthesiologist has the opportunity to discuss the various treatment modalities and potentially suggest diagnostic testing to be performed prior to delivery, similar to the pre-operative testing that is done in other surgical environments.
Contents
Abnormal Placentation -- Achondroplasia -- Acromegaly -- Acute Fatty Liver -- Adrenal Insufficiency -- Amphetamines and other Stimulant Use -- Amyotrophic lateral sclerosis -- Anticoagulation -- Antiphospholipid Syndrome -- Antithrombin deficiency -- Aortic Pathology -- Aortopulmonary and Cavopulmonary Shunts -- Arnold Chiari Malformation -- Arrhythmias - Introduction -- Arthrogryposis -- Asthma -- Atrial flutter and fibrillation -- Atrial septal defect -- Atrial Switch, Arterial Switch and Rastelli -- Atrioventricular Septal Defect AV Canal -- Autonomic Hyperreflexia -- Benzodiazepine Use -- Bernard-Soulier Syndrome -- Bone Marrow failure -- Brugada Syndrome -- Budd-Chiari Syndrome -- Caffeine Use -- Cannabis Use -- Cardiac conduction blocks -- Cardiac sinus arrhythmias -- Cardiac Valvular disorders: Introduction -- Cardiovascular Risk Assessment -- Cerebral Aneurysm -- Cerebral Ateriovenous malformations -- Charcot Marie Tooth -- Cholestasis -- Cirrhosis -- Cocaine Use -- Congenital Adrenal Hyperplasia -- Conn Syndrome -- Cushing Syndrome -- Cystic Fibrosis -- Cysticercosis -- Diabetes Insipidus -- Diabetic ketoacidosis -- Disc Herniation -- Double Outlet Right Ventricle -- Ebstein's Anomaly -- Echinococcosis -- Ehler-Danlos -- Eisenmenger's Syndrome -- Eosinophilc graunlomatosis with polyangiitis -- Essential Thrombocytemia -- Ethyl Alcohol Use -- External cephalic version -- Ex-utero intrapartum therapy -- Factor V and Combined Factor V and VIII deficiency -- Factor V Leiden and Prothrombin mutation-Common thrombophilias -- Factor VII deficiency -- Factor X deficiency -- Factor XI deficiency -- Factor XIII deficiency table -- Familial Dysautonomia -- Fibrinogen deficiency -- Glomerulonephritis -- Glucose 6 Phosphate Deficiency -- Glycogen storage diseases -- Goodpasture Syndrome -- Granulomatosis with polyangiitis -- Guillain-Barre Syndrome -- Hallucinogen Use -- Hematologic Malignancies -- Hemolytic Uremic Syndrome -- Hemophilia A and B -- Henoch Schonlein Purpura -- Hepatitis -- Hereditary motor sensory neuropathies -- Heriditary Hemorrhagic Telangetasia -- Homocystinuria -- Human immunodeficiency virus -- Hyperosmolar Hyperglycemic State -- Hyperparathyroidism -- Hypertensive Diseases -- Hypoparathyroidism -- Hypertrophic Cardiomyopathy -- Illicit Drug Use and Substance Abuse -- Immunoglobulin A Deficiency -- Inherited bleeding disorders - background -- Inherited thrombophilias-Background -- Insulin Pump -- Intracranial Hypertension -- Intracranial Mass Lesions -- Jehovah's Witnesses -- Kawasaki Disease -- Klippel-Trenaunay Syndrome -- Left Ventricular Assist Devices (LVAD) -- Long QT Syndrome -- Lysosomal storage disease -- Malignancy -- Malignant Hyperthermia -- Marfan Disease -- Mast Cell Activation Disease -- Moyamoya disease -- Multiple Sclerosis -- Myasthenia Gravis -- MYH9-related platelet disorders -- Myopathies - Congenital, Metabolic and Mitochondrial and Channelopathies -- Myopathies - Muscular Dystrophy -- Myxedema -- Nephrotic Syndrome -- Neurofibromatosis -- Obesity -- Obstructive Sleep Apnea -- Opioid Use -- Osteogenesis Imperfecta -- Pacemakers and Implantable Cardiac Defibrillators -- Panhypopituitarism -- Parkinson's Disease -- Paroxysmal supraventricular tachycardia -- Patent Ductus Arteriosus -- Peripartum Cardiomyopathy -- Phenylketonuria -- Pheochromoctoma -- Pituitary Adenoma -- Polycythemia Vera -- Porphyria -- Postpolio syndrome -- Premature cardiac contractions -- Prior Anesthetic Problems -- Prolactinomas -- Protein C and S deficiencies -- Prothrombin deficiency -- Pulmonary Fibrosis -- Pulmonary Hypertension -- Renal Disease and the Parturient on Dialysis -- Restrictive Lung Disease and Pneumothoraces -- Rheumatoid Arthritis -- Sarcoidosis -- Scoliosis -- Seizure Disorder -- Sickle Cell disease -- Single Ventricle -- Solvent Use -- Spina Bifida -- Spinal Cord Injury -- Spinal Cord Stimulators -- Spinal Muscuar Atrophy -- Spondylolysis and spondylolisthesis -- Sticky Platelet Syndrome -- Stroke during pregnancy -- Sturge-Weber -- Syndrome of the inappropriate anti-diuretic hormone -- Syringomyelia -- Systemic Lupus Erythematosis -- Systemic Sclerosis -- Tethered Cord Syndrome -- Tetralogy of Fallot -- Thalassemia -- Thrombocytopenia- An Introduction -- Thrombocytopenia-GESTATIONAL, IDIOPATHIC AND PREECLAMPSIA -- Thromboembolic Disease -- Thrombotic thrombocytopenic purpura -- Thyroid Storm -- Tobacco -- Transplantation -- Transposition of the Great Arteries -- Transverse Myelitis -- Transversus Abdominis Plane Block -- Truncus Arteriosus -- Tuberous Sclerosis -- Twin-twin transfusion syndrome and Laser Ablation -- Valvular Heat Disease- Regurgitant Lesions -- Valvular Heat Disease- Stenotic Lesions -- Vascular Malformations of the Spinal Cord -- Ventricular Septal Defect -- Ventricular tachycardia -- Ventriculoperitoneal Shunts -- Von Hippel-Lindau Syndrome -- von Willebrand Disease -- Wilson's Disease -- Wolff-Parkinson-White Syndrome.
Format
e-Book
Location
Online
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Emergencies in Neuromuscular Disease

https://libcat.nshealth.ca/en/permalink/provcat41804
Elio Agostoni, editor. --Cham: Springer , 2017.
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Online
This book offers a practical tool for handling neuromuscular emergencies, and is divided by the main neuromuscular diseases on the basis of their anatomical and clinical location: diseases affecting the anterior horn of the spinal cord (tetanus), those that affect the nerve roots and nerves (SGB, multiple mononeuritis, porphyria), the neuromuscular junction (MG and botulism) and, lastly, muscle pathologies (rhabdomyolysis, malignant hyperthermia, periodic paralysis). It provides updated diagnos…
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Other Authors
Agostoni, Elio
Responsibility
Elio Agostoni, editor
Place of Publication
Cham
Publisher
Springer
Date of Publication
2017
Physical Description
1 online resource (xv, 134 pages) : 5 illus., 3 illus. in color
Series Title
Emergency Management in Neurology
ISBN
9783319566542
9783319566535 (print ed.)
ISSN
2367-1076
Subjects (MeSH)
Clinical Decision-Making
Emergency Treatment - methods
Muscular Diseases
Nervous System Diseases
Abstract
This book offers a practical tool for handling neuromuscular emergencies, and is divided by the main neuromuscular diseases on the basis of their anatomical and clinical location: diseases affecting the anterior horn of the spinal cord (tetanus), those that affect the nerve roots and nerves (SGB, multiple mononeuritis, porphyria), the neuromuscular junction (MG and botulism) and, lastly, muscle pathologies (rhabdomyolysis, malignant hyperthermia, periodic paralysis). It provides updated diagnostic/therapeutic protocols and decision-making algorithms for each pathology, and examines a range of scenarios on the basis of clinical cases. Emergencies in Neuromuscular Disease will be of interests for a wide variety of specialists including neurologist, neurophysiologists and anesthesiologists.
Contents
Part I. Neuromuscular Disease: Recent Progress in Diagnosis and Therapy -- 1. Neuromuscular Disease: An Overview -- 2 Tetanus -- 3. Guillain-Barré Syndrome -- 4. Porphyria -- 5. Vasculitis -- 6. Myasthenia Gravis -- 7. Botulism -- 8. Malignant Hyperthermia -- 9. Rhabdomyolysis -- 10. Periodic Paralysis -- Part II. Case Studies -- 11. Case Study: Atypical GBS -- Part III. Differentiated Decisional Algorithms -- 12. Differentiated Decisional Algorithms Based on the Technical and Organizational Characteristics of the Hospital Receiving the Clinical Case.
Format
e-Book
Location
Online
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Essentials of Neurosurgical Anesthesia & Critical Care : Strategies for Prevention, Early Detection, and Successful Management of Perioperative Complications

https://libcat.nshealth.ca/en/permalink/provcat30802
Ansgar M. Brambrink, Jeffrey R. Kirsch, editors. --New York, NY: Springer , c2012.
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Location
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This handbook is aimed at first-line health care providers involved in the perioperative care of adult and pediatric neurosurgical patients. It is unique in its systematic focus on how to deal with common and important clinical challenges encountered in day-to-day practice in the OR, the PACU, and the ICU and is designed as a problem-solving tool for all members of the perioperative medicine team: trainees and faculty in anesthesiology, neurosurgery, and critical care; nurses; nurse anesthetist…
Available Online
View e-Book
Other Authors
Brambrink, Ansgar M
Kirsch, Jeffrey R
Responsibility
Ansgar M. Brambrink, Jeffrey R. Kirsch, editors
Alternate Title
Essentials of Neurosurgical Anesthesia and Critical Care
Place of Publication
New York, NY
Publisher
Springer
Date of Publication
c2012
Physical Description
1 online resource (xxx, 913 p. : 60 ill., 15 ill. in color)
ISBN
9780387095622
Subjects (MeSH)
Anesthesia
Neurosurgical Procedures
Perioperative Care
Postoperative Complications - prevention & control
Subjects (LCSH)
Anesthesiology
Critical care medicine
Neurosurgery
Abstract
This handbook is aimed at first-line health care providers involved in the perioperative care of adult and pediatric neurosurgical patients. It is unique in its systematic focus on how to deal with common and important clinical challenges encountered in day-to-day practice in the OR, the PACU, and the ICU and is designed as a problem-solving tool for all members of the perioperative medicine team: trainees and faculty in anesthesiology, neurosurgery, and critical care; nurses; nurse anesthetists; and physician's assistants. Encompasses clinical continuum from neurosurgical pre-op to critical care, plus anesthesia in neuroradiology; Adult and pediatric care; Structured algorithmic approach supports clinical decision-making; Succinct presentation of clinically relevant basic science; End-of-chapter summaries, with suggestions for further reading; Collaborative approach and multidisciplinary nature of perioperative medicine emphasized; Extensive summary tables; Portable and formatted for quick retrieval of information; Ideal for use in the OR, the PACU, and the ICU.
Contents
Preface -- Part I. Basics of Neuroanesthesia Care -- 1. The Adult Central Nervous System: Anatomy and Physiology -- 2.Neuroendocrine Physiology: Fundamentals and Common Syndromes -- 3. Cerebral Edema: Pathophysiology and Principles of Management -- 4. Management of Fluids, Electrolytes and Blood Products in Neurosurgical Patients -- 5. Key Monitoring in Neuroanesthesia: Principles, Techniques and Indications -- Part II. Preoperative Concerns of the Neuroanesthesiologist -- 6. Cardiovascular Risk and Instability: Evaluation, Management and Triage -- 7. Risk Assessment of Critical Carotid Stenosis Treatment: Suggestions for Perioperative Management -- 8. Subarachnoid Hemorrhage: Risk Assessment and Perioperative Management -- 9. Traumatic Brain Injury: Risk Assessment and Perioperative Management -- 10. Rare Neurologic Disorders and Neuromuscular Diseases: Risk Assessment and Perioperative Management -- 11. Perioperative Pharmacotherapy in Neurosurgery: Risk Assessment and Planning -- 12. Specific Considerations Regarding Consent and Communication with Patients and Family Prior to Neurosurgery -- Part III. Fundamentals of Adult Neurosurgery and Neuroanesthesia -- 13. Preparing for Anesthesia in Neurosurgical Patients -- 14. Basics of Neurosurgical Techniques and Procedures -- 15. Positioning the Patient for Neurosurgical Operations -- 16. The Intra-Operative Team: Getting the Most Out of Collaborative Care in the Operating Room -- Part IV. Critical Situations During Anesthesia for Brain Surgery in Adults -- 17. The "Tight Brain": Cerebral Herniation Syndrome -- 18. Cerebral Ischemia: Options for Perioperative Neuroprotection -- 19. Massive Hemorrhage during Craniotomy: Emergency Management -- 20. Challenges During Anesthesia for Awake Craniotomy -- 21. Perioperative Challenges During Stereotactic Neurosurgery and Deep Brain Stimulator Placement -- 22. Perioperative Challenges During Posterior Fossa Surgery -- 23. Perioperative Challenges During Release of Subdural and Epidural Hemorrhage -- 24. Perioperative Challenges During Cerebrovascular Surgery -- 25. Perioperative Challenges During Pituitary Surgery -- 26. Perioperative Challenges During Craniotomy for Space-Occupying Brain Lesions -- Part V. Critical Situations During Anesthesia for Spinal Surgery in Adults -- 27. Perioperative Challenges in Patients with Unstable Spine -- 28. Airway crisis associated with cervical spine surgery -- 29. Spinal Cord Injury During Spinal Surgery -- 30. Blood Loss During Spinal Surgery -- 31. Coagulopathy in spinal surgery -- 32. Postoperative Visual Loss Following Spinal Surgery -- Part VI. Critical Situations During Anesthesia for Other Procedures in Adult Surgery -- 33. Perioperative Challenges During Diagnostic and Perioperative Magnetic Resonance Imaging (MRI) -- 34. Perioperative Challenges During Electroconvulsive Therapy (ECT) -- 35. Perioperative Challenges During Carotid Artery Revascularization -- Part VII. Specific Perioperative Concerns in Adult Neuroanesthesia -- 36. Venous Air Embolism During Surgery -- 37. Arterial Hypotension and Hypertension During Neurosurgical Procedures -- 38. Hyperthermia and Hypothermia During Neurosurgical Procedures -- 39. Challenges Associated with Perioperative Monitoring During Neurosurgery -- 40. Unintended Wake-up During Surgery -- 41. Cardiac arrest/Code -- 42. Arousal From Anesthesia After Neurosurgical Operations -- 43. Communication Challenges During The Perioperative Period -- Part VIII. Fundamentals of Pediatric Neurosurgery and Neuroanesthesia -- 44. Anatomy and physiology of the central nervous system in children -- 45. Pediatric Anesthetic Care Requirements -- 46. The Pediatric Airway in Neurosurgery -- 47. Specific Aspects of Positioning and Fluids, Glucose, and Temperature Management in Children Undergoing Neurosurgical Procedures -- Part IX. Critical Situations During Anesthesia for Pediatric Surgery -- 48. Challenges During Surgery for Hydrocephalus -- 49. Challenges During Surgery for Traumatic Brain Injury -- 50. Challenges During Surgery for Meningomyelocele and Encephalomyelocele -- 51. Challenges During Cranial Decompression -- 52. Challenges During Surgery for Craniosynostosis and Craniofacial Surgery -- 53. Challenges During Tumor Surgery in Children and Infants -- 54. Challenges During Surgery for Vascular Anomalies in Pediatrics -- 55. Challenges During Epilepsy Surgery in Pediatric Patients -- 56. Challenges During Pediatric Endoscopic Neurosurgery -- Part X. Postoperative Concerns in Neuroanesthesia -- 57. Emergence From Anesthesia Following Pediatric Neurosurgery -- 58. Postanesthesia Care Unit Risks Following Pediatric Neurosurgery -- 59. Intensive Care Risks of Pediatric Neurosurgery -- Part XI. Fundamentals of Interventional Neuroradiology -- 60. Radiation Safety in Interventional Neuroradiology -- 61. Understanding Basic Techniques and Procedures in Interventional Neuroradiology -- 62. Basics of Image Interpretation in Interventional Neuroradiology -- Part XII. Specific Concerns Regarding Anesthesia for Interventional Neuroradiology -- 63. Procedural Challenges in Interventional Neuroradiology -- 64. Anesthesiological Challenges During Neuroradiological Interventions -- 65. Specific Challenges During Neuroradiological Interventions in Pediatric Patients -- Part XIII. Challenges During Postoperaitve Anesthesia Care After Neurosurgery -- 66. Surgical Emergencies After Neurosurgery -- 67. Airway Emergencies After Neurosurgery -- 68. Neurologic Emergencies After Neurosurgery -- 69. Hemodynamic Complications After Neurosurgery -- 70. Endocrinologic Emergencies After Neurosurgery -- 71. Postoperative Paralysis, Skin Lesions, and Corneal Abrasions After Neurosurgery -- 72. Postoperative pain management in patients after neurosurgical operations -- 73. Management of Postoperative Nausea and Vomiting After Neurosurgery -- 74. The Transport of Neurosurgical Patients -- Part XIV. Challenges in Neurocritical Care of Neurosurgical Patients -- 75. Altered Mental Status in Neurosurgical Critical Care -- 76. Cerebrovascular Vasospasm, Normal Pressure Breakthrough Edema, Posterior Reversible Encephalopathy Syndrome (PRES) in Neurosurgical Critical Care -- 77. Sedation, Analgesia, and Neuromuscular Blockade in Neurosurgical Critical Care -- 78. Airway and Pulmonary Management in Neurosurgical Critical Care -- 79. Myocardial and Vascular Management in Neurosurgical Critical Care -- 80. Nutrition and Glucose Management in Neurosurgical Critical Care -- 81. Fluid and Electrolyte Management in Neurosurgical Critical Care -- 82. Temperature Management in Neurosurgical Critical Care -- 83. Coagulation Management in Neurosurgical Critical Care -- 84. Gastrointestinal Hemorrhage in Neurosurgical Critical Care -- 85. Intracranial Monitors in Neurosurgical Critical Care -- 86. Central Nervous System Infection in Neurosurgical Critical Care -- 87. Antiepileptic Drug Therapy in Neurosurgical Critical Care -- 88. Withdrawal of mechanical ventilation in neurosurgical critical care -- 89. Brain Death in Neurosurgical Critical Care -- 90. Organ Donation in Neurosurgical Critical Care -- 91. Interaction with Family and Friends in Neurosurgical Critical Care -- Index.
Format
e-Book
Location
Online
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Essentials of Neurosurgical Anesthesia & Critical Care : Strategies for Prevention, Early Detection, and Successful Management of Perioperative Complications

https://libcat.nshealth.ca/en/permalink/provcat44992
Ansgar M. Brambrink, Jeffrey R. Kirsch, editor. (Second edition) --Cham: Springer , c2020.
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Location
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This comprehensive, evidence-based book is intended to serve as a reference for medical practitioners involved in the perioperative care of neurosurgical patients. Fundamental aspects of neuroanesthesiology and neurocritical care are thoroughly examined across 101 chapters, outlining key elements that are crucial to a care provider’s knowledge of the practice. These elements include specific diagnostic procedures and treatment options, concepts and applicable details of the available neurosurgi…
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Other Authors
Brambrink, Ansgar M.
Kirsch, Jeffrey R.
Responsibility
Ansgar M. Brambrink, Jeffrey R. Kirsch, editor
Edition
Second edition
Place of Publication
Cham
Publisher
Springer
Date of Publication
c2020
Physical Description
1 online resource (xxx, 671 p.) : 92 illus., 37 illus. in color
ISBN
9783030174101
9783030174088 (Print ed.)
9783030174095 (Print ed.)
Subjects (MeSH)
Anesthesia
Critical Care
Neurosurgical Procedures
Perioperative Care
Specialty
Anesthesiology
Neurosurgery
Abstract
This comprehensive, evidence-based book is intended to serve as a reference for medical practitioners involved in the perioperative care of neurosurgical patients. Fundamental aspects of neuroanesthesiology and neurocritical care are thoroughly examined across 101 chapters, outlining key elements that are crucial to a care provider’s knowledge of the practice. These elements include specific diagnostic procedures and treatment options, concepts and applicable details of the available neurosurgical interventions and techniques, and mechanisms necessary to provide top of the line care for patients. Each chapter features definitive and distinct areas of this multi-specialty discipline, and is designed to guide the reader from problem to solution in situations that can arise in the clinical setting. Essentials of Neurosurgical Anesthesia & Critical Care, 2nd edition is a problem-oriented approach textbook that will aid a wide variety of readers in handling day-to-day issues and developments relevant to the perioperative care of neurosurgical patients.
Contents
Part I. Basics of Neuroanesthesia Care -- 1. The Adult Central Nervous System: Anatomy and Physiology -- 2. Neuroendocrine Physiology: Fundamentals and Common Syndromes -- 3. Cerebral Edema: Pathophysiology and Principles of Management -- 4. Management of Fluids, Electrolytes and Blood Products in Neurosurgical Patients -- 5. Key Monitoring in Neuroanesthesia: Principles, Techniques and Indications -- 6. Assessing the Anesthetized State with the Electroencephalogram -- Part II. Preoperative Concerns of the Neuroanesthesiologist -- 7. Cardiovascular Risk and Instability: Evaluation, Management and Triage -- 8. Risk Assessment and Treatment of Critical Carotid Stenosis: Suggestions for Perioperative Management -- 9. Aneurysmal Subarachnoid Hemorrhage: Risk Assessment and Perioperative Complications -- 10. Traumatic Brain Injury: Risk Assessment and Perioperative Management -- 11. Rare Neurologic Disorders and Neuromuscular Diseases: Risk Assessment and Perioperative Management -- 12. Perioperative Pharmacotherapy in Neurosurgery: Risk Assessment and Planning -- 13. Specific Considerations Regarding Consent and Communication with Patients and Family Prior to Neurosurgery -- 14. Neurotoxicity of General Anesthetics -- 15. Postoperative Neurocognitive Disorders in the Geriatric Patient -- 16. The Chronic Pain Patient Scheduled For Neurosurgery -- 17. Anesthesia for Patients Scheduled for Intraoperative Electrophysiological Monitoring -- 18. Factors Influencing Outcome in Neurosurgical Anesthesia -- 19. A Comparison of Inhaled Anesthesia and Total Intravenous Anesthesia with Target-Controlled Infusion for Neuroanesthesia -- Part III. Fundamentals of Adult Neurosurgery / Neuroanesthesia -- 20. Preparing for Anesthesia in Neurosurgical Patients -- 21. Basics of Neurosurgical Techniques and Procedures -- 22. Positioning the Patient for Neurosurgical Operations -- 23. The Intraoperative Team: Getting the Most out of Collaborative Care in the Operating Room -- 24. Next Level Communication -- Part IV. Critical Situations During Anesthesia for Brain Surgery in Adults -- 25. The “Tight Brain”: Cerebral Herniation Syndrome -- 26. Cerebral Ischemia: Options for Perioperative Neuroprotection -- 27. Massive Hemorrhage During Craniotomy: Emergency Management -- 28. Challenges During Anesthesia for Awake Craniotomy -- 29. Perioperative Challenges During Stereotactic Neurosurgery and Deep Brain Stimulator Placement -- 30. Perioperative Challenges During Posterior Fossa Surgery -- 31. Perioperative Challenges During Surgical Evacuation of Subdural and Epidural Hematomas -- 32. Perioperative Challenges During Cerebrovascular Surgery -- 33. Perioperative Challenges During Pituitary Surgery -- 34. Perioperative Challenges During Craniotomy for Space-Occupying Brain Lesions -- Part V. Critical Situations During Anesthesia for Spinal Surgery in Adults -- 35. Perioperative Challenges in Patients With Unstable Spine -- 36. Airway Crisis Associated with Cervical Spine Surgery -- 37. Spinal Cord Injury During Spinal Surgery -- 38. Blood Loss During Spinal Surgery -- 39. Coagulopathy in Spinal Surgery -- 40. Postoperative Visual Loss Following Spinal Surgery -- Part VI. Critical Situations During Anesthesia for Other Procedures in Adult Neurosurgery -- 41. Perioperative Challenges During Diagnostic and Perioperative Magnetic Resonance Imaging (MRI) -- 42. Perioperative Challenges During Electro Convulsive Therapy (ECT) -- 43. Perioperative Challenges During Carotid Artery Revascularization -- VII. Specific Perioperative Concerns in Adult Neuroanesthesia -- 44. Venous Air Embolism During Neurosurgery -- 45. Arterial Hypotension, Hypertension -- 46. Hyperthermia and Hypothermia During Neurosurgical Procedures -- 47. Challenges Associated with Perioperative Monitoring During Neurosurgery -- 48. Unintended Wake-up During Neurosurgery -- 49. Cardiac Arrest/Code -- 50. Arousal from Anesthesia: Failure to Emerge -- 51. Communication Challenges During the Perioperative Period -- Part VIII. Fundamentals of Pediatric Neurosurgery and Neuroanesthesia -- 52. Anatomy and Physiology of the Central Nervous System in Children -- 53. Pediatric Anesthetic Care Requirements -- 54. The Pediatric Airway in Neurosurgery -- 55. Specific Aspects of Positioning, Fluids, Glucose Control and Temperature Management -- Part IX. Critical Situations During Anesthesia for Pediatric Neurosurgery -- 56:Challenges During Surgery for Hydrochephalus -- 57. Challenges During Surgery for Traumatic Brain Injury in Children and Adults -- 58. Challenges During Surgery for Meningomyelocele and Encephalomyelocele -- 59. Challenges During Cranial Decompression -- 60. Challenges During Surgery for Craniosynostosis and Craniofacial Surgery -- 61. Challenges During Tumor Surgery in Children and Infants -- 62. Challenges During Surgery for Vascular Anomalies in Pediatrics -- 63. Challenges During Epilepsy Surgery in Pediatric Patients -- 64. Challenges During Pediatric Endoscopic Neurosurgery -- 65. Challenges During Diagnostic and Perioperative Imaging in Children with Brain Pathology -- Part X. Postoperative Concerns in Pediatric Neuroanesthesia -- 66. Emergence from Anesthesia Following Pediatric Neurosurgery -- 67. Postanesthesia Care Unit Risks Following Pediatric Neurosurgery -- 68. Intensive Care Risks of Pediatric Neurosurgery -- Part XI. Fundamentals of Interventional Neuroradiology -- 69. Radiation Safety in Interventional Neuroradiology -- 70. Understanding Basic Techniques and Procedures in Interventional Neuroradiology -- 71. Basics of Image Interpretation in Interventional Neuroradiology -- Part XII. Specific Concerns Regarding Anesthesia for Interventional Neuroradiology -- 72. Procedural Challenges in Interventional Neuroradiology -- 73. Anesthesiological Challenges During Neuroradiological Interventions -- 74. Specific Challenges during Neuroradiologic Interventions in Pediatric Patients -- Part XIII. Challenges During Postoperative Anesthesia Care After Neurosurgery -- 75. Surgical Emergencies After Neurosurgery -- 76. Postoperative Respiratory Complications -- 77. Neurologic Emergencies After Neurosurgery -- 78. Hemodynamic Complications After Neurosurgery -- 79. Endocrinologic Emergencies After Neurosurgery -- 80. Postoperative Paralysis, Skin Lesions and Corneal Abrasions After Neurosurgery -- 81. Postoperative Pain Management in Patients After Neurosurgical Operations -- 82. Management of Postoperative Nausea and Vomiting After Neurosurgery -- 83. The Intrahospital Transport of Neurosurgical Patients -- Part XIV. Challenges in Neurocritical Care of Neurosurgical Patients -- 84. Altered Mental Status in Neurosurgical Critical Care -- 85. Cerebrovascular Vasospasm, Normal Pressure Breakthrough Edema, Posterior Reversible Encephalopathy Syndrome (PRES) in Neurosurgical Critical Care -- 86. Sedation, Analgesia, and Neuromuscular Blockade in Neurosurgical Critical Care -- 87. Airway and Pulmonary Management in Neurosurgical Critical Care -- 88. Myocardial and Vascular Management in Neurosurgical Critical Care -- 89. Nutrition and Glucose -- 90. Fluid and Electrolyte Management in Neurosurgical Critical Care -- 91. Temperature Management in Neurosurgical Critical Care -- 92. Coagulation Management in Neurosurgical Critical Care -- 93. Gastrointestinal Hemorrhage in Neurosurgical Critical -- 94. Intracranial Monitors in Neurosurgical Critical Care -- 95. Central Nervous System Infection in Neurosurgical Critical Care -- 96. Antiepileptic Drug Therapy in Neurosurgical Critical Care -- 97. Withdrawal of Mechanical Ventilation in Neurosurgical Critical Care -- 98. Brain Death in Neurosurgical Critical Care -- 99. Organ Donation -- 100. Interaction with Family and Friends in Neurosurgical Critical Care.
Format
e-Book
Location
Online
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Genetic neuromuscular disorders : a case-based approach

https://libcat.nshealth.ca/en/permalink/provcat33906
Corrado Angelini. --Cham, Switzerland: Springer , c2014.
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Location
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This book describes the genetic diagnostic entities of neuromuscular disorders. Each neuromuscular syndrome is presented clinically as a case study, accompanied by text reviewing different molecular defects, DNA research and differential diagnosis. This collection of neuromuscular disorders features the different clinical phenotypes related to each genotype and are representative of the whole spectrum of a genetic muscle disorder, helping the clinician and neuromuscular physician to make a diag…
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Author
Angelini, C.
Responsibility
Corrado Angelini
Place of Publication
Cham, Switzerland
Publisher
Springer
Date of Publication
c2014
Physical Description
1 online resource (xxi, 384 pages)
ISBN
9783319075006 (electronic bk.)
9783319074993
Subjects (MeSH)
Genetic Diseases, Inborn - Case Reports
Neuromuscular Diseases - genetics - Case Reports
Subjects (LCSH)
Neuromuscular diseases - Genetic aspects - Case studies
Neurology
Abstract
This book describes the genetic diagnostic entities of neuromuscular disorders. Each neuromuscular syndrome is presented clinically as a case study, accompanied by text reviewing different molecular defects, DNA research and differential diagnosis. This collection of neuromuscular disorders features the different clinical phenotypes related to each genotype and are representative of the whole spectrum of a genetic muscle disorder, helping the clinician and neuromuscular physician to make a diagnosis. Key points for each genetic disease are identified to suggest treatment, when available, or the main clinical exams useful in follow-up of patients. Genetic Neuromuscular Disorders: A Case-Based Approach is aimed at neuromuscular physicians and neurology residents.
Contents
Part I. Muscular Dystrophies -- Duchenne Muscular Dystrophy -- Duchenne Muscular Dystrophy Carrier -- Becker Muscular Dystrophy -- Emery-Dreifuss Muscular Dystrophy type 1 -- Emery-Dreifuss Muscular Dystrophy type 2 -- Limb Girdle Muscular Dystrophy type 1B -- Limb Girdle Muscular Dystrophy type 1C -- Limb Girdle Muscular Dystrophy type 1F -- Limb Girdle Muscular Dystrophy type 2A -- Limb Girdle Muscular Dystrophy type 2B -- Limb Girdle Muscular Dystrophy type 2C -- Limb Girdle Muscular Dystrophy type 2D -- Limb Girdle Muscular Dystrophy type 2E -- Limb Girdle Muscular Dystrophy type 2F -- Limb Girdle Muscular Dystrophy type 2I -- Limb Girdle Muscular Dystrophy type 2K -- Limb Girdle Muscular Dystrophy type 2N -- Congenital Muscular Dystrophy type 1A -- Congenital Muscular Dystrophy type 1C -- Congenital Muscular Dystrophy with rigid spine -- Congenital Muscular Dystrophy with integrin-alpha-7 deficiency -- Congenital Muscular Dystrophy, Ullrich type -- Bethlem myopathy -- Facio Scapulo Humeral Muscular Dystrophy type 1A -- Facio Scapulo Humeral Muscular Dystrophy type 2 -- Section 2: Congenital Myopathies -- Congenital Multi-Mini-Core Myopathy -- Congenital Central-Core Myopathy with Malignant Hyperthermia -- Congenital Centronuclear Myopathy type 1 -- Congenital Hyaline Body Myopathy -- Congenital Myotubular Myopathy -- Congenital Nemaline Myopathy type 2 -- Congenital Fiber Type Disproportion type 1 -- Congenital Fiber Type Disproportion -- Congenital Myofibrillar Myopathy type 1 -- Congenital Myofibrillar Myopathy type 6 -- Congenital Tubular Aggregate Myopathy -- Hereditary Inclusion Body Myopathy type 2 -- Section 3: Ion Channel Disorders -- Myotonic Dystrophy type 1, Steinert Disease -- Congenital Myotonic Dystrophy -- Myotonic Dystrophy type 2, Proximal Myotonic Myopathy -- Congenital Myotonia, Thomsen Disease -- Hyperkalemic Periodic Paralysis -- Hypokalemic Periodic Paralysis type 1 -- Slow-channel Congenital Myasthenic Syndrome -- Congenital Myasthenic Syndrome -- Brody Disease -- Section 4: Metabolic Myopathies -- Glycogenosis type 2, Pompe Disease -- Glycogenosis type 3, Cori-Forbes Disease -- Glycogenosis type 5, McArdle Disease -- Danon Disease -- Kearns-Sayre Syndrome -- Chronic Progressive External Ophthalmoplegia -- MELAS (Myopathy, Encephalopathy, Lactic Acidosis, Stroke-like) -- Leigh Syndrome due to COX Deficiency -- Mitochondrial Encephalopathy with COX Deficiency -- Coenzyme Q10 Deficiency -- Multiple Symmetrical Lipomatosis -- NARP (Neuropathy, Ataxia, Retinitis Pigmentosa) -- SANDO (Sensory Ataxic Neuropathy, Dysarthria, Ophthalmoparesis) -- Systemic Primary Carnitine Deficiency -- Neutral Lipid Storage Disease with Ichthyosis -- Neutral Lipid Storage Disease with Myopathy -- Multiple Acyl-CoA Dehydrogenase Deficiency -- Carnitine-Palmitoyl-Transferase-II Deficiency -- Niemann-Pick Disease type C1 -- Section 5: Neurogenic Disorders -- Spinal Muscular Atrophy type 1, Werdnig-Hoffmann Disease -- Spinal Muscular Atrophy type 2 -- Spinal Muscular Atrophy type 3, Kugelberg-Welander Disease -- Spinal Bulbar Muscular Atrophy, Kennedy Disease -- Charcot-Marie-Tooth Disease type 1A -- Charcot-Marie-Tooth Disease type 1B -- Charcot-Marie-Tooth Disease neuronal type -- Charcot-Marie-Tooth Disease type 4A -- Charcot-Marie-Tooth Disease with pyramidal features -- Charcot-Marie-Tooth Disease type X1 -- Distal Spinal Muscular Atrophy -- Hereditary Neuropathy with Pressure Palsies -- Friedreich Ataxia -- Spastic Ataxia, Charlevoix-Saguenay type -- Ataxia-Telangiectasia, Louis-Bar Syndrome -- Spastic Paraparesis type 4 -- Spastic Paraparesis type 7 -- Optic Atrophy Plus Syndrome -- Amyotrophic Lateral Sclerosis type 1 -- Amyotrophic Lateral Sclerosis.
Format
e-Book
Location
Online
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Heat Stress in Sport and Exercise : Thermophysiology of Health and Performance

https://libcat.nshealth.ca/en/permalink/provcat44235
Julien D. Périard, Sébastien Racinais, editors. --Cham: Springer , 2019.
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Location
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The book is designed to provide a flowing description of the physiology of heat stress, the illnesses associated with heat exposure, recommendations on optimising health and performance, and an examination of Olympic sports played in potentially hot environmental conditions. In the first section the book examines how heat stress effects performance by outlining the basics of thermoregulation and how these responses impact on cardiovascular, central nervous system, and skeletal muscle function. …
Available Online
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Other Authors
Périard, Julien D.
Racinais, Sébastien.
Responsibility
Julien D. Périard, Sébastien Racinais, editors
Place of Publication
Cham
Publisher
Springer
Date of Publication
2019
Physical Description
1 online resource (viii, 296 p.) : 55 illus., 48 illus. in color
ISBN
9783319935157
9783319935140 (Print ed.)
9783319935164 (Print ed.)
Subjects (MeSH)
Body Temperature Regulation - physiology
Heat-Shock Response - physiology
Heat Stress Disorders - prevention & control
Sports Medicine
Specialty
Physiology
Sports Medicine
Abstract
The book is designed to provide a flowing description of the physiology of heat stress, the illnesses associated with heat exposure, recommendations on optimising health and performance, and an examination of Olympic sports played in potentially hot environmental conditions. In the first section the book examines how heat stress effects performance by outlining the basics of thermoregulation and how these responses impact on cardiovascular, central nervous system, and skeletal muscle function. It also outlines the pathophysiology and treatment of exertional heat illness, as well as the role of hydration status during exercise in the heat. Thereafter, countermeasures (e.g. cooling and heat acclimation) are covered and an explanation as to how they may aid in decreasing the incidence of heat illness and minimise the impairment in performance is provided. A novel and particular feature of the book is its inclusion of sport-specific chapters in which the influence of heat stress on performance and health is described, as well as strategies and policies adopted by the governing bodies in trying to offset the deleterious role of thermal strain. Given the breadth and scope of the sections, the book will be a reference guide for clinicians, practitioners, coaches, athletes, researchers, and students.
Contents
Part I. The Physiology of Heat Stress -- 1. Human Thermoregulation -- 2. The Biophysics of Human Heat Exchange -- 3. Integrative Human Cardiovascular Responses to Hyperthermia -- 4. Neural and Muscular Function in the Heat -- Part II. Heat Illnesses and Countermeasures -- 5. Common Misconceptions in Classic and Exertional Heat Stroke -- 6. Hydration in Sport and Exercise -- 7. Heat-Stress Exercise and Cooling -- 8. Heat Acclimation -- Part III. Application to Specific Sports -- 9. The Application of Heat Stress to Team Sports: Football/Soccer, Australian Football and Rugby -- 10. Heat Stress During American Football -- 11. Tennis in the Heat -- 12. Athletics: Track and Field in the Heat -- 13. Cycling in the Heat -- 14. Open-Water Swimming -- 15. Triathlon and Ultra-Endurance Events in Tropical Environments.
Format
e-Book
Location
Online
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Hyperthermic Oncology from Bench to Bedside

https://libcat.nshealth.ca/en/permalink/provcat40453
Satoshi Kokura, Toshikazu Yoshikawa, Takeo Ohnishi, editors. --Singapore: Springer , c2016.
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Location
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This comprehensive work broadens readers' understanding of the rudimentary mechanism of the anti-cancer effect of hyperthermia. It also presents state-of-the-art clinical outcomes by hyperthermia treatment of cancer. In the past few decades, basic and clinical research have shown through in vitro experiments that hyperthermia inhibits epithelial-mesenchymal transition (EMT), resulting in the prevention of metastasis. It also has been learned that hyperthermia shows its superior benefit when app…
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Other Authors
Kokura, Satoshi
Yoshikawa, Toshikazu
Ohnishi, Takeo
Responsibility
Satoshi Kokura, Toshikazu Yoshikawa, Takeo Ohnishi, editors
Place of Publication
Singapore
Publisher
Springer
Date of Publication
c2016
Physical Description
1 online resource (x, 444 p. : 155 illus., 85 illus. in color)
ISBN
9789811007194
9789811007170 (print ed.)
Subjects (MeSH)
Drug Therapy, Combination
Hot Temperature
Hyperthermia, Induced - methods
Neoplasms - therapy
Radiotherapy - methods
Abstract
This comprehensive work broadens readers' understanding of the rudimentary mechanism of the anti-cancer effect of hyperthermia. It also presents state-of-the-art clinical outcomes by hyperthermia treatment of cancer. In the past few decades, basic and clinical research have shown through in vitro experiments that hyperthermia inhibits epithelial-mesenchymal transition (EMT), resulting in the prevention of metastasis. It also has been learned that hyperthermia shows its superior benefit when applied in combination with radiation therapy, chemotherapy, or various immunotherapies as treatments of several types of carcinoma. The chapters here from expert contributors describe the details of their research for each type of cancer. This book provides not only an overview and the current status of hyperthermia but also its future perspectives. Therefore this volume will greatly benefit oncologists, radiologists and radiology technologists, and chemotherapists who are involved in immunotherapy for all kinds of cancer.
Contents
Part I. Basic Science in Cultured Cells -- 1. Introduction -- 2. Induction of oxidative stress by hyperthermia and enhancement of hyperthermia-induced apoptosis by oxidative stress modification -- 3. Molecular Damage: Hyperthermia Alone -- 4. Roles of HSF1 and Heat Shock Proteins in Cancer -- 5. Cellular Responses in Signal Transduction Pathways Induced by Hyperthermia -- 6. Cell cycle responses to hyperthermia -- 7. Thermo-tolerance -- 8. Enhancement of Hyperthermia on Radio-sensitivity -- 9. Inhibition of DNA repair system activity -- 10. Enhancement of Hyperthermia on Anti-tumor Drug Sensitivity -- 11. Inhibition of epithelial-to-mesenchymal transition (EMT) by hyperthermia -- Part II. Basic Science in Whole Body -- 12. Potentiating Immune System by Hyperthermia -- 13. Magnetic Nanoparticle-Mediated Hyperthermia and Induction of Anti-Tumor Immune Responses -- 14. Tumor Microenvironment and Hyperthermia -- Part III. Clinical Science in Cancer Patients -- 15. Hyperthermia Alone -- 16. Combination by Hyperthermia and Radiation (and Chemotherapy): Oral and Maxillofacial Cancer -- 17. Combination by Hyperthermia and Radiation (and Chemotherapy): Lung Cancer -- 18. Efficacy of hyperthermia in combination with radiation therapy for breast cancer -- 19. Combination by Hyperthermia and Radiation: Esophageal Cancer -- 20. Combination by Hyperthermia and Radiation (and Chemotherapy): Gynecology Cancer -- 21. Combination by Hyperthermia and Radiation and Chemotherapy: Soft Tissue Sarcoma -- 22. Combination by Hyperthermia and Chemotherapy: Lung Cancer -- 23. Combination by Hyperthermia and Chemotherapy: Breast Cancer -- 24. Combination by Hyperthermia and Chemotherapy: Esophageal Cancer -- 25. Combination by Hyperthermia and Chemotherapy: Liver Cancer -- 26. Hyperthermia Combined with Chemotherapy: Pancreatic Cancer -- 27. Effect of hyperthermia in combination with chemotherapy and radiation therapy for treatment of urological cancer (prostate cancer and urothelial cancer) -- 28. Combination by Hyperthermia and Surgery -- 29. Combining Hyperthermia and Immunotherapy: NK Therapy and Hyperthermia -- 30. Combination by Hyperthermia and Immunotherapy: DC Therapy and Hyperthermia -- 31. Effects of fever-range hyperthermia on T cell-mediated immunity: possible combination of hyperthermia and T cell-based cancer immunotherapy -- 32. Combination of Hyperthermia and Immunotherapy: Hyperthermia and Naive T-cell Therapy -- 33. HIPEC for Peritoneal Dissemination -- 34. A new comprehensive treatment for peritoneal metastases using cytoreductive surgery combined with hyperthermic intraperitoneal chemoperfusion -- 35. Non-invasive Temperature Moniterring -- 36. Development of Heating Device -- 37. Epilogue.
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e-Book
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Online
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Imaging and Technology in Urology : Principles and Clinical Applications

https://libcat.nshealth.ca/en/permalink/provcat30881
Steve Payne, Ian Eardley, Kieran O'Flynn, editors. --London: Springer , c2012.
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Imaging and Technology in Urology: Principles and Clinical Applications is a practical and user-friendly consolidated source book for urologists, and urologists in training, regarding the basic science of imaging modalities used on a day-to-day basis in urological practice. Similarly, the intention is to provide an introduction to the technology that is used in the practice of urological surgery and the management of urological patients in the clinical setting. This knowledge is one of the eigh…
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Other Authors
Payne, Steve
Eardley, Ian
O'Flynn, Kieran
Responsibility
Steve Payne, Ian Eardley, Kieran O'Flynn, editors
Place of Publication
London
Publisher
Springer
Date of Publication
c2012
Physical Description
1 online resource (xvi, 385 p. : 113 ill., 67 ill. in color)
ISBN
9781447124221
Subjects (MeSH)
Diagnostic Techniques, Urological
Urography - methods
Subjects (LCSH)
Radiology, Medical
Urology
Abstract
Imaging and Technology in Urology: Principles and Clinical Applications is a practical and user-friendly consolidated source book for urologists, and urologists in training, regarding the basic science of imaging modalities used on a day-to-day basis in urological practice. Similarly, the intention is to provide an introduction to the technology that is used in the practice of urological surgery and the management of urological patients in the clinical setting. This knowledge is one of the eight separate disciplines examined in the oral component of the knowledge examination for independent, consultant, practice in urology in the UK. The book is also valuable to urologists and urological trainees outside of the UK and in other surgical specialities.
Contents
Part 1 Imaging: Radiology -- Principles of X-ray Production and Radiation Protection -- How to Perform a Clinical Radiograph and Use a C-arm -- Contrast agents -- How to do an IVU -- Dual Energy X-Ray Absorptiometry (DXA) -- The physics of ultrasound -- How to Ultrasound a Suspected Renal Mass -- How to Ultrasound a Painful Testis and a Testicular Mass -- How to Perform a Trans-Rectal Ultrasound Scan and Prostate Biopsy -- How to Manage a Hydronephrotic Kidney -- Principles of Computed Tomography (CT) -- How to do a CT Urogram (CTU) -- How to do a CT in a Patient with Presumed Upper Tract Trauma -- Principles of Magnetic Resonance Imaging (MRI) -- How to do an MRI of the Pelvis -- Magnetic Resonance Angiography (MRA) -- Vascular Embolization Techniques in Urology -- Part 2 Imaging: Nuclear Medicine -- Radionuclides and their Uses in Urology -- Counting and Imaging in Nuclear Medicine -- Principles of Positron Emission Tomography (PET) Scanning -- How to do a Renogram -- How to do a Diuresis Renogram -- How to do a DMSA Scan -- How to do a Radioisotope Glomerular Filtration Rate Study -- How to do a Bone Scan -- How to do a Transplant Renogram -- Dynamic Sentinel Lymph Node Biopsy in Penile Cancer -- Part 3 Technology: Diagnostic -- Urinalysis -- Principles of Urine Microscopy and Microbiological Culture -- Measurement of Glomerular Filtration Rate (GFR) -- Metabolic Assessment of Urinary Tract Stones -- Principles of Pressure Measurement -- Principles of Measurement of Urinary Flow -- How to Carry Out a Videocystometrogram (VCMG) -- The Whitaker test -- Sphincter electromyography (EMG) -- Tumour Markers -- Urine Cytology -- Histopathological Processing, Staining and Immunohistochemistry -- Part 4 Technology: Operative -- Principles of Urological Endoscopes -- Rigid Endoscope Design -- Light Sources, Light Leads and Camera Systems -- Peripherals for Endoscopic Use -- Peripherals for laparoscopic use -- Peripherals for mechanical stone manipulation -- Contact lithotripters -- Endoscopic use of Laser Energy -- Double J Stents and Nephrostomy -- Urinary Catheters, Design and Usage -- Prostatic and Urethral Stents -- Urological Prosthetics -- Meshes in Stress Urinary Incontinence and Pelvic Organ Prolapse -- Biological meshes -- Principles of Tissue Transfer in Urology -- Theatre Design and Patient Safety -- Deep Venous Thrombosis (DVT) Prevention -- Principles of Decontamination -- Operative Tissue Destruction -- Sutures and Clips -- Monopolar Diathermy -- Bipolar Diathermy -- Alternatives to Electro-Surgery -- Haemostatic Agents, Sealants and Adhesives -- Irrigation Fluids and their Hazards -- Insufflants and their Hazards -- Laparoscopic Ports -- Setting up a Robot -- Part 5 Technology: Interventional -- Neuromodulation by sacral nerve stimulation -- Principles of Extracorporeal Shockwave Lithotripsy (ESWL) -- How to carry out Shockwave Lithotripsy -- Prostatic Hyperthermia -- Ablative Therapies: High Intensity Focused Ultrasound (HIFU), Cryotherapy and Radio-Frequency Ablation (RFA) -- Principles of Radiotherapy -- Electro-Motive Drug Administration (EMDA) -- Part 6 Technology of Renal Failure -- Principals of Renal Replacement Therapy (RRT) -- Principals of Peritoneal Dialysis -- Haemodialysis -- Principles of Renal Transplantation -- Part 7 - Assessment of Technology -- Randomised Controlled Trials (RCTs) -- Health Technology Assessment.
Format
e-Book
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Online
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Induction Chemotherapy : Systemic and Locoregional

https://libcat.nshealth.ca/en/permalink/provcat40104
Karl Reinhard Aigner, Frederick O. Stephens, editors. (2nd ed.) --Cham: Springer , c2016.
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This book presents the full range of management techniques and practices used in induction chemotherapy--both systemic and locoregional--by experienced international groups within one accessible volume. It provides the latest information on the pioneering and cutting-edge practices employed in different institutions and documents the advantages of integrated treatment schedules. All those responsible for treating patients with locally advanced cancers may find new, interesting aspects of locore…
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Other Authors
Aigner, Karl Reinhard
Stephens, Frederick O
Responsibility
Karl Reinhard Aigner, Frederick O. Stephens, editors
Edition
2nd ed.
Place of Publication
Cham
Publisher
Springer
Date of Publication
c2016
Physical Description
1 online resource (vii, 506 p. : 131 illus., 86 illus. in color)
ISBN
9783319287737
9783319287713 (print ed.)
Subjects (MeSH)
Antineoplastic Agents - administration & dosage
Induction Chemotherapy - methods
Infusions, Intra-Arterial - methods
Neoplasms - drug therapy
Remission Induction - methods
Abstract
This book presents the full range of management techniques and practices used in induction chemotherapy--both systemic and locoregional--by experienced international groups within one accessible volume. It provides the latest information on the pioneering and cutting-edge practices employed in different institutions and documents the advantages of integrated treatment schedules. All those responsible for treating patients with locally advanced cancers may find new, interesting aspects of locoregional cancer management and will find this book to be an invaluable source of up-to-date information. Throughout the world, induction chemotherapy is being used as part of an integrated plan of management for locally advanced, solid tumors, while systemic chemotherapy is most commonly used to shrink primarily non-operable tumors. In cases of poorly or nonresponsive tumors, attempts have been made to administer chemotherapeutics via the arterial route in order to achieve higher localized drug exposure and response rates. Such therapies are being practiced worldwide in independent, remote departments in universities, teaching hospitals and clinical schools. Frequently, however, these teams remain relatively unaware of the work being done in other institutions, which may slow further progress.
Contents
Introduction: Overview, History, Terminology and Early Clinical Experience -- The Principle of Dose-Response in Antineoplastic Drug Delivery -- Drug Removal Systems and Induction Chemotherapy -- Cryotherapy -- Local and Regional Hyperthermia -- The Role of Hypoxia and Hyperthermia in Chemotherapy -- Induction Chemotherapy in Head and Neck Cancers -- Isolated Thoracic Perfusion with Carotid Artery Infusion for Advanced and Chemoresistant Tumors of the Parotid Gland -- Induction Chemotherapy For Breast Cancer -- Patients with Locally Advanced Breast Cancer receiving Intra-Arterial Induction Chemotherapy: report of a Phase II Clinical Study -- Regional Chemotherapy with Thoracic Wall Recurrence and Metastasized Breast Cancer -- Cytoreductive Surgery and ÇHyperthermic Intraperitoneal Chemotherapy-HIPEC -- Induction Bidirectional Chemotherapy for Gastric Cancer with Peritoneal Dissemination -- Esophageal Cancer -- Gastric Cancer -- Systemic and Regional Chemotherapy for Advanced and Metastasized Pancreatic Cancer -- Interventional Radiological Procedures for Port-Catheter Implantation -- Induction chemotherapy for hepatocellular carcinoma -- Transarterial Treatment of Primary and Secondary Liver Tumors -- Pelvic Perfusion for Rectal Cancer -- Isolated Pelvic Perfusion with Chemofiltration for Pelvic Malignancies: Anal, Cervical and Bladder Cancer -- Penile cancer treated by intra-arterial infusion chemotherapy -- Systemic Induction Chemotherapy for Advanced Stage Epithelial Ovarian Cancer -- Regional Chemotherapy in Recurrent Platinum-Refractory Ovarian Cancer -- Isolated Limb Perfusion for Melanoma -- Isolated Limb Infusion -- Induction treatment in sarcomas -- Isolated Limb Perfusion for Locally Advanced Soft Tissue Sarcoma -- Induction Chemotherapy in Treatment of Sarcomas -- Isolation Perfusion Systems: Lungs -- Metastatic Cancers in Lung: Isolated Lung Perfusio: Clinical Studies -- Isolated Thoracic Perfusion with Chemofiltration (ITP-F) for Advanced and Pre-treated Non-Small-Cell Lung Cancer -- Toxicity Profiles with Systemic versus Regional Chemotherapy.
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e-Book
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Online
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Innate tolerance in the CNS : translational neuroprotection by pre- and post-conditioning

https://libcat.nshealth.ca/en/permalink/provcat32302
Jeffrey M. Gidday, Miguel A. Perez-Pinzon, John H. Zhang, editors. --New York, NY: Springer , c2013.
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Cerebral ischemia from cardiac arrest, stroke, and subarachnoid and intracerebral hemorrhage, together with trauma, epilepsy, and other CNS pathologies, continue to impose immense burdens of morbidity and mortality the world over. Despite many decades of research aimed at understanding the genetic and molecular basis of these pathologies, therapeutics developed on the basis of blocking known injury mechanisms can actually claim few clinical successes. The field of CNS "preconditioning" was born…
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Other Authors
Gidday, Jeffrey M
Perez-Pinzon, Miguel A
Zhang, John H
Responsibility
Jeffrey M. Gidday, Miguel A. Perez-Pinzon, John H. Zhang, editors
Place of Publication
New York, NY
Publisher
Springer
Date of Publication
c2013
Physical Description
1 online resource (ix, 699 p. : 60 ill., 44 ill. in color)
Series Title
Springer series in translational stroke research
ISBN
9781441996954
Subjects (MeSH)
Brain Ischemia - prevention & control
Ischemic Postconditioning - methods
Ischemic Preconditioning - methods
Neuroprotective Agents
Subjects (LCSH)
Neurosciences
Neurology
Neurobiology
Abstract
Cerebral ischemia from cardiac arrest, stroke, and subarachnoid and intracerebral hemorrhage, together with trauma, epilepsy, and other CNS pathologies, continue to impose immense burdens of morbidity and mortality the world over. Despite many decades of research aimed at understanding the genetic and molecular basis of these pathologies, therapeutics developed on the basis of blocking known injury mechanisms can actually claim few clinical successes. The field of CNS "preconditioning" was born from the preclinical finding more than 20 years ago that intentional activation of innate, cytoprotective factors could provide robust protection, or "tolerance" against cerebral ischemic injury. Herein, up-to-date summaries on all aspects of preconditioning for CNS disease, including the emerging topics of postconditioning and remote pre- and post-conditioning, are provided by the leading scientists in the field. The translational potential of both preclinical and clinical advances is underscored throughout, with the hope of accelerating the bench-to-bedside success of endogenous cytoprotection as a therapeutic strategy.Jeffrey M. Gidday PhD, Associate Professor of Neurosurgery at Washington University School of Medicine, has been working in the field of CNS preconditioning for 18 years, and has numerous publications on preconditioning-induced protection in the setting of several different cerebral and retinal pathologies. Miguel A. Perez-Pinzon PhD is Professor of Neurology/Neuroscience, Vice-Chair for Basic Science of Neurology at the University of Miami Miller School of Medicine. He began studies of ischemic preconditioning in 1995 and for many years prior to that worked in the field of anoxia tolerance, publishing close to 50 peer-reviewed articles and many book chapters on these topics. John H. Zhang MD PhD is Professor of Neurosurgery, Anesthesiology, and Physiology, and Vice-Chair of the Basic Science Department at the Loma Linda University School of Medicine. His research interests include stroke and medical gases, and he has published papers related to pre-, post- and remote-conditioning in subarachnoid hemorrhage, focal cerebral ischemia, and neonatal brain injury.
Contents
Preface -- Section I. Comparative Physiology and Historical Background -- 1. Tolerance, Historical Review -- 2. Anoxia resistance in lower and higher vertebrates -- 3. Hibernation: A Natural Model of Tolerance to Cerebral Ischemia/Reperfusion -- 4. Preconditioning in the Heart -- Section II. Conditioning Methods -- 5. Neuroprotection and Physical Preconditioning: Exercise, Hypothermia, and Hyperthermia -- 6. A New Future in Brain Preconditioning Based on Nutraceuticals: Focus on -Linolenic Omega-3 Fatty Acids for Stroke Protection -- 7. Medical Gases for Conditioning: Volatile Anesthetics, Hyperbaric Oxygen, and Hydrogen Sulfide -- 8. Hypoxic Preconditioning in the CNS -- 9. Pharmacologic Preconditioning -- 10. Surgical Methods to Induce Brain Preconditioning -- Section III.Conditioning Models for Cerebral Ischemia -- 11. Tolerance Against Global Cerebral Ischemia: Experimental Strategies, Mechanisms, and Clinical Applications -- 12. Preconditioning and Neuroprotection in the Immature Brain -- 13. Conditioning Studies in Focal Cerebral Ischemia: Model Selection, Physiological Monitoring, and Other Methodological Issues -- 14. Preconditioning for Subarachnoid Hemorrhage -- 15. Preconditioning for Intracerebral Hemorrhage -- 16. The Protective Effects of Ischemic Postconditioning in Experimental Stroke -- Section IV.Mechanisms of Preconditioning -- 17. Synaptic Signaling in Ischemic Tolerance -- 18 -- The Genomics of Preconditioning and Ischemic Tolerance -- 19. How do Subcellular Organelles Participate in Preconditioning-Conferred Neuroprotection? -- 20. Ischemic Preconditioning Mediated Signaling Pathways Lead to Tolerance Against Cerebral Ischemia -- 21. Preconditioning the Neurovascular Unit: Tolerance in the Brain's Non-Neuronal Cells -- Section V. Other Neurological Disorders -- 22. Preconditioning for Surgical Brain Injury -- 23. Intrinsic Neuroprotection in Traumatic Brain Injury -- 24. Preconditioning for Epilepsy -- 25. Ischemic Pre- and Post-Conditioning in the Retina -- Section VI. Clinical Applications -- 26. Clinical Cerebral Ischemic Preconditioning -- 27. Preconditioning Strategy: áCoronary Bypass, Subarachnoid Hemorrhage, Temporary Proximal Vessel Occlusion in Carotid Revascularization, and Intracranial Aneurysm Surgery -- 28. HBO preconditioning for TBI and Stroke Patients -- 29. Electroacupuncture Preconditioning for Stroke Patients -- 30. Clinical Trials of Ischemic Conditioning -- Epilogue -- Index.
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e-Book
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Online
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Intraperitoneal Cancer Therapy

https://libcat.nshealth.ca/en/permalink/provcat28434
edited by C. William Helm, Robert P. Edwards. --Totowa, NJ: Humana Press , c2007.
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Online
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Author
Helm, C. William
Other Authors
Edwards, Robert P
Responsibility
edited by C. William Helm, Robert P. Edwards
Place of Publication
Totowa, NJ
Publisher
Humana Press
Date of Publication
c2007
Series Title
Current clinical oncology
ISBN
9781597451956
Subjects (MeSH)
Colorectal Neoplasms - therapy
Hyperthermia, Induced
Ovarian Neoplasms - therapy
Subjects (LCSH)
Abdomen - Surgery
Cancer - Surgery
Gynecology
Notes
"This collaborative work is the result of a gathering of some of the leaders in the field of intraperitoneal chemotherapy for ovarian cancer and hyperthermic intraperitoneal chemotherapy for peritoneal carcinomatosis at an international symposium held at the University of Louisville, Kentucky, in May 2005. All the speakers at that symposium have contributed chapters to this work"-- P. v.
Contents
Management of ovarian cancer : the theory -- Management of ovarian cancer : clinical trials-- A systematic review and meta-analysis of randomized trials -- Immunobiology and intraperitoneal immunobiologics in ovarian cancer -- Intraperitoneal chemotherapy : technique and complications -- Hyperthermia and chemotherapy : the science -- Hyperthermic intraperitoneal chemotherapy in nongynecologic cancers -- Peritoneal carcinomatosis of colorectal origin -- Cytoreductive surgery and hyperthermic intraperitoneal chemotherapy for ovarian cancer : experience in France -- Cytoreductive surgery and hyperthermic intraperitoneal chemotherapy for ovarian cancer : world experience -- Techniques of delivering hyperthermic intraperitoneal chemotherapy -- Future directions in the delivery of hyperthermic intraperitoneal chemotherapy.
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e-Book
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Online
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Malignant Mesothelioma and Pseudomyxoma

https://libcat.nshealth.ca/en/permalink/provcat44067
Mikhail V. Kiselevskiy, Amir G. Abdulaev, Mikhail M. Davydov, editors. --Cham: Springer , 2019.
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This book covers different aspects of the rare neoplasms – malignant mesothelioma and pseudomyxoma peritonei. The monograph includes up-to-date information on etiology, pathogenesis and diagnostics of malignant mesothelioma and pseudomyxoma peritonei, as well as detailed description of surgical and combined treatment of patients with these diseases. The book comprises a large illustrative material presented by schemes and original micrographs that represent pathological and immunohistochemical …
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Other Authors
Kiselevskiy, Mikhail V.
Abdulaev, Amir G.
Davydov, Mikhail M.
Responsibility
Mikhail V. Kiselevskiy, Amir G. Abdulaev, Mikhail M. Davydov, editors
Place of Publication
Cham
Publisher
Springer
Date of Publication
2019
Physical Description
1 online resource (x, 121 p.) : 40 illus., 38 illus. in color
ISBN
9783319995106
9783319995090 (Print ed.)
9783319995113 (Print ed.)
Subjects (MeSH)
Mesothelioma, Malignant
Pseudomyxoma Peritonei
Specialty
Medical Oncology
Pulmonary Medicine
Abstract
This book covers different aspects of the rare neoplasms – malignant mesothelioma and pseudomyxoma peritonei. The monograph includes up-to-date information on etiology, pathogenesis and diagnostics of malignant mesothelioma and pseudomyxoma peritonei, as well as detailed description of surgical and combined treatment of patients with these diseases. The book comprises a large illustrative material presented by schemes and original micrographs that represent pathological and immunohistochemical specific features of these malignancies, demonstrate the stages of surgical operations and hyperthermic intraperitoneal chemotherapy, and show the results of experimental studies. The book includes validated discussion on etiology and pathogenesis of malignant mesothelioma and pseudomyxoma peritonei, differential diagnosis and treatment of these diseases. The scope is really extensive and involves, for instance, a description of the technique of cytoreductive surgeries and regimens of intraperitoneal hyperthermic chemoperfusion, whereas a particular section discusses experimental ground for optimal regimens of hyperthermia, local chemotherapy and adoptive immunotherapy by cytokine induced killers. The final section presents the most recent data about perspective approaches for immunotherapy of malignant mesothelioma and pseudomyxoma peritonei with cell based technologies and target drugs including inhibitors of immune checkpoints. The co-authors of the book are leading specialists in this area, surgeons and scientists who present the results of their research along with the analysis of the state-of-the-art of this problem. The book is designed for a wide audience of students and professors of medical universities and schools, specialists of research and diagnostic centers, practical oncologists and immunologists, as well as doctors of different medical areas.
Contents
Mesothelioma and pseudomyxoma peritonei: incidence, etiology, diagnosis -- Pathology of selected primary and metastatic tumors of peritoneum -- Treatment of patients with pseudomyxoma peritonei and peritoneal mesothelioma -- Standardizing of mesothelioma and pseudomyxoma care -- Experimental substantiation of optimal regimes of hyperthermic peritoneal chemotherapy -- Immunotherapy of malignant peritoneal mesothelioma and pseudomixoma peritonei.
Format
e-Book
Location
Online
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Neuromuscular Urgencies and Emergencies

https://libcat.nshealth.ca/en/permalink/provcat45634
Niraj Arora, Raghav Govindarajan, Saurabh Kataria, Premkumar Nattanmai Chandrasekaran, editors. --Cham: Springer , c2020.
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This book functions as a practical reference for recognizing various patient presentations, signs, and symptoms that must be considered when treating neuromuscular disorders (NMD). It emphasizes the importance of recognizing these preexisting conditions as this can be crucial to treating patients properly with appropriate medications and procedures. Concise yet comprehensive, this 10-chapter guide analyses various neuromuscular weaknesses including respiratory and progressive muscle weakness. C…
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Other Authors
Arora, Niraj
Govindarajan, Raghav
Kataria, Saurabh
Nattanmai Chandrasekaran, Premkumar
Responsibility
Niraj Arora, Raghav Govindarajan, Saurabh Kataria, Premkumar Nattanmai Chandrasekaran, editors
Place of Publication
Cham
Publisher
Springer
Date of Publication
c2020
Physical Description
1 online resource (xiv, 221 p.) : 33 illus., 14 illus. in color
ISBN
9783030531454
9783030531447 (Print ed.)
9783030531461 (Print ed.)
9783030531478 (Print ed.)
Subjects (MeSH)
Emergencies
Neuromuscular Diseases - diagnosis
Neuromuscular Manifestations
Specialty
Emergency Medicine
Neurology
Abstract
This book functions as a practical reference for recognizing various patient presentations, signs, and symptoms that must be considered when treating neuromuscular disorders (NMD). It emphasizes the importance of recognizing these preexisting conditions as this can be crucial to treating patients properly with appropriate medications and procedures. Concise yet comprehensive, this 10-chapter guide analyses various neuromuscular weaknesses including respiratory and progressive muscle weakness. Chapters address the involvement of multiple organ systems in NMD, with specific attention to cardiomyopathy, cardiac arrhythmias, and dystrophinopathies. Discussions also address the challenges practitioners face when treating vulnerable demographics such as pregnant women and those with hyper metabolic conditions. Written by experts in the field, Neuromuscular Urgencies and Emergencies is an invaluable resource for neurologists, emergency medicine physicians, physician assistants, and the interventional neurologist.
Contents
1. Approach to Weakness -- 2. Neuromuscular Respiratory Weakness -- 3. Rapidly Progressive Muscle Weakness -- 4. Cardiac Complications Associated with Neuromuscular Diseases -- 5. Neuromuscular Emergencies in the Neuroscience Intensive Care Unit -- 6. Anesthesia-Related Complications in Neuromuscular Disorders in Adults -- 7. Pregnancy and Neuromuscular Emergencies -- 8. Malignant Hyperthermia -- 9. Pediatric Neuromuscular Emergencies and Urgencies -- 10. Management of Pain in Neuromuscular Disorders.
Format
e-Book
Location
Online
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Pediatric critical care medicine. Volume 4, Peri-operative care of the critically ill or injured child

https://libcat.nshealth.ca/en/permalink/provcat33338
Derek S. Wheeler, Hector R. Wong, Thomas P. Shanley, editors. (Second edition) --London: Springer , c2014.
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The Editors and contributors of this book take seriously the statement that For all of the science inherent in the specialty of pediatric critical care medicine, there is still art in providing comfort and solace to our patients and their families. No technology will ever replace the compassion in the touch of a hand or the soothing words of a calm and gentle voice. The four volumes of Pediatric Critical Care Medicine: Basic Science and Clinical Evidence, 2nd Edition detail the continued growth…
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Other Authors
Wheeler, Derek S
Wong, Hector R
Shanley, Thomas P
Responsibility
Derek S. Wheeler, Hector R. Wong, Thomas P. Shanley, editors
Edition
Second edition
Alternate Title
Peri-operative care of the critically ill or injured child
Perioperative care of the critically ill or injured child
Place of Publication
London
Publisher
Springer
Date of Publication
c2014
Physical Description
1 online resource (xxii, 466 pages)
ISBN
9781447163596 (electronic bk.)
9781447163589
Subjects (MeSH)
Critical Illness - therapy
Perioperative Care
Anesthesia - methods
Wounds and Injuries - surgery
Cardiac Surgical Procedures
Organ Transplantation - methods
Subjects (LCSH)
Pediatric intensive care
Médecine
Abstract
The Editors and contributors of this book take seriously the statement that For all of the science inherent in the specialty of pediatric critical care medicine, there is still art in providing comfort and solace to our patients and their families. No technology will ever replace the compassion in the touch of a hand or the soothing words of a calm and gentle voice. The four volumes of Pediatric Critical Care Medicine: Basic Science and Clinical Evidence, 2nd Edition detail the continued growth and evolution of the pediatric critical care medicine speciality. They reveal the technological innovations in monitoring and information management and gives witness to the rapid evolution and adoption of novel monitoring techniques, such as continuous venous oximetry and near-infrared spectroscopy. They also cover advances in molecular biology that have led to the era of personalized medicine with the ability to individualize treatment to the unique and specific needs of a patient. As such this volume and its three sister titles will be of immense value to all studying and practicing pediatric critical care medicine or those involved in the management of this group of patients.
Contents
Part I. Anesthesia in the Critically Ill or Injured Child -- Preparing the Critically Ill or Injured Child for Surgery -- Pharmacology of Inhalational and Intravenous Anesthetic Agents -- Sedation and Analgesia -- Tolerance, Physical Dependency, and Withdrawal -- Neuromuscular Blockade -- Procedural Sedation and Anesthesia in the PICU -- Blood Conservation in the Perioperative Setting -- Malignant Hyperthermia -- Part II. General Principles of Peri-operative Care -- Peri-operative Care of the General Pediatric Surgical Patient -- Perioperative Care of the Pediatric Neurosurgical Patient -- Perioperative Care of the Urology Patient -- Perioperative Care of the Orthopaedic Surgery Patient -- Peri-operative Care of the ENT Patient -- Part III. Trauma -- Head and Neck Trauma -- Craniofacial Trauma -- Thoracic Trauma -- Abdominal Trauma -- Genitourinary Trauma -- Pediatric Orthopaedic Trauma -- Pediatric Burns -- Part IV. Cardiac Surgery and Critical Care -- The Systemic Inflammatory Response to Cardiopulmonary Bypass: Pathophysiology and Treatment -- Myocardial Protection -- Surgical Interventions for Congenital Heart Disease -- Palliative Procedures -- Peri-operative Care of the Child with Congenital Heart Disease -- Part V. Critical Care of the Solid Organ Transplant Patient -- Pharmacology of Immunosuppression -- Heart Transplantation -- Pediatric Lung Transplantation -- Pediatric Liver Transplantation -- Intestinal/Multivisceral Transplantation -- Kidney Transplantation.
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e-Book
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Online
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