Andrological Evaluation of Male Infertility : A Laboratory Guide
https://libcat.nshealth.ca/en/permalink/provcat40017
Ashok Agarwal, Sajal Gupta, Rakesh Sharma, editors.
--Cham:
Springer
, c2016.
- Available Online
- View e-Book
- Location
- Online
This state-of-the-art laboratory manual includes 20 clinical protocols used daily for the investigation of the infertile male, presented with easy to understand, step-by-step methodology. The protocols are arranged from routine to advanced laboratory procedures common to clinical practice, including computer-assisted semen analysis, sperm preparation for IUI by density gradient and swim-up, sperm cryopreservation, and sperm DNA fragmentation test by TUNEL method, among others. The methodology i…
- Available Online
- View e-Book
- Other Authors
- Agarwal, Ashok
- Gupta, Sajal
- Sharma, Rakesh
- Responsibility
- Ashok Agarwal, Sajal Gupta, Rakesh Sharma, editors
- Place of Publication
- Cham
- Publisher
- Springer
- Date of Publication
- c2016
- Physical Description
- 1 online resource (xii, 215 p. : 122 illus.)
- ISBN
- 9783319267975
- 9783319267951 (print ed.)
- Subjects (MeSH)
- Infertility, male
- Reproductive Techniques, Assisted
- Semen Analysis
- Abstract
- This state-of-the-art laboratory manual includes 20 clinical protocols used daily for the investigation of the infertile male, presented with easy to understand, step-by-step methodology. The protocols are arranged from routine to advanced laboratory procedures common to clinical practice, including computer-assisted semen analysis, sperm preparation for IUI by density gradient and swim-up, sperm cryopreservation, and sperm DNA fragmentation test by TUNEL method, among others. The methodology in each protocol follows best practice guidelines made clearer by professionally hand-drawn illustrations covering most of the important steps and equipment. The authors, hailing from the world-renowned Andrology Center at Cleveland Clinic, have over 50 years of combined first-hand experience in managing very busy diagnostic and research facilities in male infertility and andrology. The book will be an indispensable resource for thousands of laboratory technologists, clinicians and reproductive professionals (andrologists, embryologist, etc.) engaged in the diagnosis and management of infertile men around the world.
- Format
- e-Book
- Publication Type
- Laboratory Manuals
- Location
- Online
Antioxidants in Andrology
https://libcat.nshealth.ca/en/permalink/provcat41396
Giancarlo Balercia, Loredana Gandini, Andrea Lenzi, Francesco, editors Lombardo, editors.
--Cham:
Springer
, 2017.
- Available Online
- View e-Book
- Location
- Online
This book focuses on the use of various molecules with antioxidant properties in the treatment of major male genital tract disorders, especially male infertility, erectile dysfunction, and accessory gland infection. The coverage also includes discussion of pathophysiology, the molecular basis of male infertility, and the rationale for use of antioxidants, with particular attention to coenzyme Q10 and carnitine. Oxidative stress occurs when the production of reactive oxygen species, including fr…
- Available Online
- View e-Book
- Other Authors
- Balercia, Giancarlo
- Gandini, Loredana
- Lenzi, Andrea
- Lombardo, Francesco
- Responsibility
- Giancarlo Balercia, Loredana Gandini, Andrea Lenzi, Francesco, editors Lombardo, editors
- Place of Publication
- Cham
- Publisher
- Springer
- Date of Publication
- 2017
- Physical Description
- 1 online resource (vii, 79 pages) : 7 illus. in color
- Series Title
- Trends in andrology and sexual medicine
- ISBN
- 9783319417493
- 9783319417479 (print ed.)
- ISSN
- 2367-0088
- Subjects (MeSH)
- Andrology
- Antioxidants - pharmacology
- Antioxidants - therapeutic use
- Genital Diseases, Male - drug therapy
- Infertility, Male - drug therapy
- Oxidative Stress - physiology
- Sexual Dysfunction, Physiological - drug therapy
- Carnitine - physiology
- Ubiquinone - analogs & derivatives
- Abstract
- This book focuses on the use of various molecules with antioxidant properties in the treatment of major male genital tract disorders, especially male infertility, erectile dysfunction, and accessory gland infection. The coverage also includes discussion of pathophysiology, the molecular basis of male infertility, and the rationale for use of antioxidants, with particular attention to coenzyme Q10 and carnitine. Oxidative stress occurs when the production of reactive oxygen species, including free radicals, exceeds the body's natural antioxidant defences, leading to cellular damage. Oxidative stress is present in about half of all infertile men, and reactive oxygen species can produce infertility both by damaging the sperm membrane, with consequences for sperm motility, and by altering the sperm DNA. There is consequently a clear rationale for the use of antioxidant treatments within andrology, and various in vitro and in vivo studies have indicated that many antioxidants indeed have beneficial impacts. In providing a detailed and up-to-date overview of the subject, this book will be of interest to both practitioners and researchers in andrology, endocrinology, and urology.
- Contents
- 1. Free Radicals in Andrology -- 2. Biochemistry of Coenzyme Q10 -- 3. Carnitine in Male Infertility -- 4. Coenzyme Q10 in Male Infertility -- 5. Antioxidants in Male Accessory Gland Infection -- 6. Antioxidants in Male Sexual Dysfunctions.
- Format
- e-Book
- Location
- Online
Atlas of Imaging in Infertility : A Complete Guide Based in Key Images
https://libcat.nshealth.ca/en/permalink/provcat41252
Luis Ronan Marquez Ferreira de Souza, Ana Luisa Alencar De Nicola, Harley De Nicola, editors.
--Cham:
Springer
, 2017.
- Available Online
- View e-Book
- Location
- Online
This atlas gathers the most frequent imaging findings concerning alterations that cause infertility in both males and in females. Also, it discusses how the images should be analyzed and described, to serve as a guide for the physicians who request and perform these imaging tests. Infertility is a highly prevalent condition: about 10% of couples are infertile with males and females equally affected. This book offers professionals dealing with infertility, including endocrinologists, gynecologis…
- Available Online
- View e-Book
- Responsibility
- Luis Ronan Marquez Ferreira de Souza, Ana Luisa Alencar De Nicola, Harley De Nicola, editors
- Place of Publication
- Cham
- Publisher
- Springer
- Date of Publication
- 2017
- Physical Description
- 1 online resource (xii, 214 pages) : 298 illus., 193 illus. in color
- ISBN
- 9783319138930
- 9783319138923 (print ed.)
- Abstract
- This atlas gathers the most frequent imaging findings concerning alterations that cause infertility in both males and in females. Also, it discusses how the images should be analyzed and described, to serve as a guide for the physicians who request and perform these imaging tests. Infertility is a highly prevalent condition: about 10% of couples are infertile with males and females equally affected. This book offers professionals dealing with infertility, including endocrinologists, gynecologists and urologists, a useful guide to the diagnostic imaging tests that are essential in treating these patients. The Atlas of Imaging in Infertility is a valuable resource for physicians from different specialties managing cases of infertility.
- Contents
- 1. Anatomy and Embryology -- Part I: Imaging of Female Infertility -- 2 Polycystic Ovarian Syndrome -- 3. Tubal Diseases -- 4. Pelvic Inflammatory Disease -- 5. Endometriosis -- 6. Leiomyoma and Cavitary Lesions -- 7. Adenomyosis -- 8. Müllerian Duct Anomalies -- Part II: Imaging of Male Infertility -- 9. Obstructive Disorders -- 10. Non-obstructive Diseases of the Testes -- Part III: Other Diseases -- 11. The Sella Turcica -- 12. Adrenal Gland Diseases.
- Format
- e-Book
- Publication Type
- Atlas
- Location
- Online
A Clinician's Guide to Sperm DNA and Chromatin Damage
https://libcat.nshealth.ca/en/permalink/provcat43221
Armand Zini, Ashok Agarwal, editors.
--Cham:
Springer
, c2018.
- Available Online
- View e-Book
- Location
- Online
This comprehensive, up-to-date text, which brings together the key practical elements of the rapidly evolving field of sperm DNA and chromatin abnormalities, is divided thematically into five main sections. Part I discusses human sperm chromatin structure and nuclear architecture, while part II presents laboratory evaluation of sperm DNA damage, including SCSA, SCD, TUNEL and Comet assays, and cytochemical tests. Biological and clinical factors in the etiology of sperm DNA damage are discussed …
- Available Online
- View e-Book
- Other Authors
- Zini, Armand
- Agarwal, Ashok
- Responsibility
- Armand Zini, Ashok Agarwal, editors
- Place of Publication
- Cham
- Publisher
- Springer
- Date of Publication
- c2018
- Physical Description
- 1 online resource (xix, 605 p.)
- ISBN
- 9783319718156
- 9783319718149 (print ed.)
- 9783319718163 (print ed.)
- Subjects (MeSH)
- Chromatin - pathology
- DNA Damage
- Infertility, Male - etiology
- Spermatozoa - pathology
- Abstract
- This comprehensive, up-to-date text, which brings together the key practical elements of the rapidly evolving field of sperm DNA and chromatin abnormalities, is divided thematically into five main sections. Part I discusses human sperm chromatin structure and nuclear architecture, while part II presents laboratory evaluation of sperm DNA damage, including SCSA, SCD, TUNEL and Comet assays, and cytochemical tests. Biological and clinical factors in the etiology of sperm DNA damage are discussed in part III, including oxidative stress, abortive apoptosis, cancer, and environmental and lifestyle factors. Part IV presents clinical studies on the utility of sperm DNA damage tests, both with natural and ART-assisted pregnancies, and debates the clinical utility of such tests. Finally, part V discusses current treatment options, such as antioxidant therapy, varicocelectomy, advanced sperm processing techniques and the use of testicular sperm. We are now beginning to better understand the unique organization of the sperm chromatin, as well as the nature and etiology of sperm DNA damage. Written and edited by worldwide experts in andrology, A Clinician's Guide to Sperm DNA and Chromatin Damage is an excellent resource for reproductive medicine and REI specialists, urologists, reproductive biologists and any professional working with the infertile male.
- Contents
- Part I. Human Sperm Chromatin Structure -- 1. Sperm Chromatin: An Overview -- 2. Sperm Nucleoproteins (Histones and Protamines) -- 3. Sperm Nuclear Architecture -- Part II. Laboratory Evaluation of Sperm Chromatin and DNA Damage -- 4. Sperm Chromatin Structure Assay (SCSA®): Evolution from Origin to Clinical Utility -- 5. TUNEL Assay -- 6. TUNEL Assay by Benchtop Flow Cytometer in Clinical Laboratories -- 7. The Comet Assay -- 8. Sperm Chromatin Dispersion (SCD) Assay -- 9. Cytochemical Tests of Sperm Chromatin Maturity -- 10. Is There an Optimal Sperm DNA Test? -- Part III. Etiology of Sperm DNA Damage: Biological and Clinical Factors -- 11. Oxidative Stress -- 12. Apoptosis in Ejaculated Spermatozoa and in the Normal and Pathological Testes: Abortive Apoptosis and Sperm Chromatin Damage -- 13. Defective DNA Repair in Spermiogenesis -- 14. Defective Spermatogenesis and Sperm DNA Damage -- 15. Sperm Chromatin and Lifestyle Factors -- 16. Cancer and Sperm DNA Damage -- 17. Sperm Chromatin and Environmental Factors -- 18. Sperm DNA Damage and Oocyte Repair Capability -- Part IV. Clinical Studies on Utility of Sperm DNA Damage Tests -- 19. Experimental Studies on Sperm DNA Fragmentation and Reproductive Outcomes -- 20. Sperm DNA and Natural Pregnancy -- 21. Sperm DNA and ART (IUI, IVF, ICSI) Pregnancy -- 22. Sperm DNA and Pregnancy Loss After IVF and ICSI -- 23. Sperm DNA Tests Are Clinically Useful: Pro -- 24. Sperm DNA Tests Are Clinically Useful: CON -- Part V. Treatment Options for Men with Sperm DNA Damage -- 25. Antioxidant Therapy -- 26. Varicocelectomy -- 27. Physiological Intracytoplasmic Sperm Insemination Based on Hyaluronic Acid-Binding Ability -- 28. Advanced Sperm Processing/Selection Techniques -- 29. Use of Testicular Sperm for ICSI: Pro -- 30. Debate on the Use of Testicular Sperm for ICSI: Con -- 31. Strategies to Diminish DNA Damage in Sperm Samples Used for ART -- 32. Sperm DNA Testing: Where Do We Go from Here?
- Format
- e-Book
- Location
- Online
Development of In Vitro Maturation for Human Oocytes : Natural and Mild Approaches to Clinical Infertility Treatment
https://libcat.nshealth.ca/en/permalink/provcat41722
Ri-Cheng Chian, Geeta Nargund, Jack Y. J. Huang, editors.
--Cham:
Springer
, 2017.
- Available Online
- View e-Book
- Location
- Online
An ideal reference for infertility specialists and reproductive endocrinologists alike, this comprehensive text discusses current natural and mild approaches to in vitro fertilization (IVF) and the development of in vitro maturation (IVM) as a clinical treatment. It is divided thematically into four sections. Part I presents the basic science of ovarian endocrinology and the mechanism of oocyte maturation, including follicular development and the importance of mitochondrial changes. The differe…
- Available Online
- View e-Book
- Other Authors
- Chian, Ri-Cheng
- Nargund, Geeta
- Huang, Jack Y. J
- Responsibility
- Ri-Cheng Chian, Geeta Nargund, Jack Y. J. Huang, editors
- Place of Publication
- Cham
- Publisher
- Springer
- Date of Publication
- 2017
- Physical Description
- 1 online resource (xvii, 376 pages) : 67 illus., 56 illus. in color
- ISBN
- 9783319534541
- 9783319534527 (print ed.)
- Subjects (MeSH)
- In Vitro Oocyte Maturation Techniques
- Infertility, Female - therapy
- Oocytes - growth & development
- Ovarian Hyperstimulation Syndrome - prevention & control
- Ovulation Induction - adverse effects
- Ovulation Induction - methods
- Abstract
- An ideal reference for infertility specialists and reproductive endocrinologists alike, this comprehensive text discusses current natural and mild approaches to in vitro fertilization (IVF) and the development of in vitro maturation (IVM) as a clinical treatment. It is divided thematically into four sections. Part I presents the basic science of ovarian endocrinology and the mechanism of oocyte maturation, including follicular development and the importance of mitochondrial changes. The differences between natural cycle IVF and stimulated IVF are presented in part II, including the standard ovarian stimulation protocols and their outcomes and the etiology, prevention and management of ovarian hyperstimulation syndrome (OHSS). Minimal and mild stimulation for IVF is discussed in part III, including mild stimulation protocols for oncofertility patients and the new minimally invasive INVO procedure. In vitro maturation as a clinical treatment is the subject of part IV, discussing the methodology of immature oocyte retrieval as well as other laboratory aspects and congenital and obstetrical outcomes of babies born from IVM. Combining expertise from thought leaders around the world, Development of In Vitro Maturation for Human Oocytes will be a go-to resource for infertility researchers and practitioners and reproductive endocrinologists working with infertile couples looking for safer and more cost-effective options for treatment.
- Contents
- Part I: Ovarian Function -- Ovarian Endocrinology -- Follicular Development and Oocyte Growth -- A New Understanding of the Regulation of Oocyte Meiotic Prophase Arrest and Resumption -- Mitochondria of the Oocyte -- Part II: Natural Cycle IVF and Stimulation Cycle IVF -- Natural Cycle IVF: Summary of the Current Literature -- Follicular Fluid Hormone Profiles in Natural Cycle IVF Patients during Follicular Phase -- Standard Ovarian Stimulation Protocols and Their Outcomes -- Which Women Are Suitable for Natural and Modified Natural Cycle IVF? -- Natural Cycle IVF with Spontaneous LH Surge -- Etiologies and Risk Factors of Ovarian Hyperstimulation Syndrome -- Prevention and Management of Ovarian Hyperstimulation Syndrome -- Part III: Minimal or Mild Stimulation for IVF -- Cumulative Pregnancy Rates after Six Cycles of Modified Natural Cycle IVF -- Minimal Stimulation for IVF with Clomiphene Citrate -- Mild Stimulation Protocols: Combination of Clomiphene Citrate and Recombinant FSH or HMG -- Mild Stimulation Protocol for Poor Ovarian Responders Undergoing IVF -- The Application of Natural Cycle IVF in Primary Ovarian Insufficiency -- Mild Stimulation Protocols for Oncofertility Patients -- Minimally Invasive IVF as an Alternative Treatment Option for Infertile Couples: (INVO) Procedure -- Accessible Infertility Care: From Dream to Reality -- Genetic Aspects of Recurrent Implantation Failure -- Part IV: Development of In Vitro Maturation -- IVM as Clinical Treatment: Overview -- Avoidance of Severe Ovarian Hyperstimulation with IVM Treatment -- Immature Oocyte Retrieval for IVM Treatment -- Laboratory Aspect of IVM Treatment -- Obstetric Outcomes of In Vitro Maturation Treatment and Risk of Congenital Malformations -- Development of IVM Treatment: Combination of Natural Cycle IVF with IVM.
- Format
- e-Book
- Location
- Online
The Diagnosis and Treatment of Male Infertility : A Case-Based Guide for Clinicians
https://libcat.nshealth.ca/en/permalink/provcat41801
Nabil Aziz, Ashok Agarwal, editors.
--Cham:
Springer
, 2017.
- Available Online
- View e-Book
- Location
- Online
This case-based guide is written from the clinician's perspective, dealing with a defined male infertility problem, tracing the actual clinical pathway arriving at the diagnosis, and discussing the treatment options and the likely outcome. Rather than focusing on excessive theoretical details, each chapter presents a unique clinical vignette or scenario, the relevant aspects of which are followed throughout the entire chapter, correlating specific fertility issues with clinical findings, descri…
- Available Online
- View e-Book
- Other Authors
- Aziz, Nabil
- Agarwal, Ashok
- Responsibility
- Nabil Aziz, Ashok Agarwal, editors
- Place of Publication
- Cham
- Publisher
- Springer
- Date of Publication
- 2017
- Physical Description
- 1 online resource (xiv, 304 pages) : 38 illus., 34 illus. in color
- ISBN
- 9783319565477
- 9783319565453 (print ed.)
- Subjects (MeSH)
- Infertility, Male - diagnosis
- Infertility, Male - therapy
- Abstract
- This case-based guide is written from the clinician's perspective, dealing with a defined male infertility problem, tracing the actual clinical pathway arriving at the diagnosis, and discussing the treatment options and the likely outcome. Rather than focusing on excessive theoretical details, each chapter presents a unique clinical vignette or scenario, the relevant aspects of which are followed throughout the entire chapter, correlating specific fertility issues with clinical findings, describing treatment options, prognoses and procedures (when indicated), and concluding with practical clinical pearls. Opening with chapters describing current diagnoses of male infertility and semen analysis, the subsequent cases presented cover a variety of relevant topics in male infertility, including anabolic steroid use, ejaculatory and erectile dysfunction, azoospermia, Klinefelter Syndrome, varicocele, cystic fibrosis and spinal cord injury. Additional chapters discuss choosing the right assisted conception technique and developing and managing a sperm bank. Practical and illustrative of a wide array of male fertility issues, The Diagnosis and Treatment of Male Infertility is a go-to resource for clinical andrologists, reproductive endocrinologists, urologists, primary care physicians and any professional working to treat the infertile male.
- Contents
- Making a Diagnosis -- Interpreting Semen Analysis and Level 2 Sperm Testing -- Medical and Lifestyle Approaches to Improving Semen Quality -- Testosterone and Anabolic Steroid Abuse -- Managing Infertility Due to Endocrine Causes -- Management of Infections in Male Infertility -- Ejaculatory Dysfunction: Retrograde Ejaculation -- Management of Azoospermia -- Klinefelter Syndrome -- CFTR-Related Male Infertility -- Sperm Retrieval Techniques -- Varicocele: Surgical Intervention vs. Assisted Conception -- Treating Erectile Dysfunctions -- Spinal Cord Injury-Related Infertility -- Establishing and Managing a Sperm Bank -- Assisted Conception Techniques: Which One to Choose.
- Format
- e-Book
- Location
- Online
Emerging Topics in Reproduction. Volume 5
https://libcat.nshealth.ca/en/permalink/provcat42580
Douglas T. Carrell, Catherine Racowsky, Peter N. Schlegel, Alan H. DeCherney, editors.
--Cham:
Springer
, c2018.
- Available Online
- View e-Book
- Location
- Online
Previously known as Biennial Review of Infertility, the fifth installment in this series brings together the most current research and clinical evidence on male and female infertility, emerging assisted reproductive technologies (ART) and evolving controversies in reproductive medicine. In this latest volume, parts one and two discuss recent developments in male and female infertility respectively, including fertility preservation in the male adolescent cancer patient, the clinical relevance of…
- Available Online
- View e-Book
- Responsibility
- Douglas T. Carrell, Catherine Racowsky, Peter N. Schlegel, Alan H. DeCherney, editors
- Former Title
- Biennial review of infertility
- Place of Publication
- Cham
- Publisher
- Springer
- Date of Publication
- c2018
- Physical Description
- 1 online resource (xiii, 243 p.) : 39 illus., 21 illus. in color
- ISBN
- 9783319908236
- 9783319908229 (print ed.)
- 9783319908243 (print ed.)
- Subjects (MeSH)
- Infertility
- Reproductive Techniques, Assisted
- Reproductive Medicine
- Specialty
- Reproductive Medicine
- Abstract
- Previously known as Biennial Review of Infertility, the fifth installment in this series brings together the most current research and clinical evidence on male and female infertility, emerging assisted reproductive technologies (ART) and evolving controversies in reproductive medicine. In this latest volume, parts one and two discuss recent developments in male and female infertility respectively, including fertility preservation in the male adolescent cancer patient, the clinical relevance of sperm RNA, the management of subclinical hypothyroidism, and the effects of endocrine-disrupting chemicals. Part three covers the latest in ART, such as evidence-based morphological approaches for embryo selection and culturing human embryos. The final section highlights controversies in reproductive medicine, including the use of preimplantation genetic screening (PGS) and blastocyst transfer, as well as the ethics surrounding a maximum BMI for IVF. Providing an ongoing appraisal of current knowledge, and featuring contributions from leading experts in the field, Emerging Topics in Reproduction, Volume 5 is a worthy addition to the series and an ideal resource on the latest topics for reproductive medicine and REI specialists, OB-GYNS, andrologists, and any clinician working with infertility.
- Contents
- Part I: Male -- TESE for Cryptozoospermia with Normal Sperm DNA Fragmentation -- The Argument for Varicocele Repair in Non-Obstructive Azoospermia -- Current and Future Perspectives on Sperm RNAs -- Male Infertility as a Marker of Future Health -- Fertility Preservation in the Male Adolescent Patient -- Part II: Female -- Advanced Imaging Techniques Used in the Infertile Female -- Treatment of Subclinical Hypothyroidism in the Infertile Female -- Endocrine-Disrupting Chemicals and Female Infertility -- Part III: ART [Assisted Reproductive Technologies] -- Is There an Optimum System for Culturing Human Embryos?- Evidence-Based Approaches to Embryo Selection by Morphology and Kinetics -- Part IV: Controversies -- Is It Good Practice/Ethical to Set a Max BMI Before IVF? -- Are We Closer to "Freeze-All" for ART? -- Preimplantation Genetic Screening: Not for Everyone -- Should All Patients Undergo Blastocyst Transfer? No.
- Format
- e-Book
- Location
- Online
Female Reproductive Dysfunction
https://libcat.nshealth.ca/en/permalink/provcat45018
edited by Felice Petraglia, Bart CJM Fauser.
--Cham:
Springer
, 2020.
- Available Online
- View e-Book
- Location
- Online
Written by leading international specialists, this book provides a comprehensive, state-of-the-art overview of endocrine-based female reproductive disorders. Particularly focusing on the Hypothalamus – Pituitary – Ovary (HPO) axis as the main driver of reproduction in women, it discusses amenorrhea; chronic anovulation and polycystic ovary syndrome as the most common dysfunctions of the HPO axis; endocrine diseases as possible impacts on the HPO axis; uterine disorders related to estrogen/proge…
- Available Online
- View e-Book
- Other Authors
- Petraglia, Felice
- Fauser, Bart CJM
- Responsibility
- edited by Felice Petraglia, Bart CJM Fauser
- Place of Publication
- Cham
- Publisher
- Springer
- Date of Publication
- 2020
- Physical Description
- 1 online resource (x, 400 p.)
- Series Title
- Endocrinology
- Springer reference
- ISBN
- 9783030035945
- ISSN
- 2510-1927
- Subjects (MeSH)
- Endocrine System Diseases
- Infertility, Female - etiology
- Reproductive Health
- Women's Health
- Specialty
- Gynecology
- Reproductive Medicine
- Notes
- "Living reference work."
- Abstract
- Written by leading international specialists, this book provides a comprehensive, state-of-the-art overview of endocrine-based female reproductive disorders. Particularly focusing on the Hypothalamus – Pituitary – Ovary (HPO) axis as the main driver of reproduction in women, it discusses amenorrhea; chronic anovulation and polycystic ovary syndrome as the most common dysfunctions of the HPO axis; endocrine diseases as possible impacts on the HPO axis; uterine disorders related to estrogen/progesterone; and the impact of endometriosis and uterine fibroids on reproduction. It also addresses infertility and menopause as hormone-related disorders in women and endocrine changes during pregnancy and lactation. The book is intended as a major reference for endocrinologists, gynecologists, and obstetricians, as well as basic and clinical scientists. It is published as part of the SpringerReference program, which provides access to live editions constantly updated through a dynamic peer-review publishing process.
- Contents
- Abnormal Uterine Bleeding -- Assisted Reproductive Technologies -- Climacteric Syndrome -- Diagnostic Protocols for Infertility -- Endocrinology of Maternal-Placental Axis -- Endometriosis -- Hormonal Contraception -- Hormonal Treatments in the Infertile Women -- Hormone Replacement Therapy (HRT) -- Hormones and Sex Behavior -- Hormones, Breast Disorders, and Lactation -- Infertility -- Long-Term Consequences of Menopause -- Menopause and Bone Metabolism -- Menstrual Disorders Related to Endocrine Diseases -- Premature Ovarian Insufficiency -- The Hypothalamus-Pituitary-Ovary Axis -- The Menstrual Cycle and Related Disorders -- The Menstrual Disorders Related to Systemic Diseases -- The Polycystic Ovary Syndrome (PCOS) -- The “Great Obstetrical Syndromes” -- Uterine Fibroids and Adenomyosis.
- Format
- e-Book
- Location
- Online
Frontiers in Gynecological Endocrinology. Volume 9, Endometriosis Pathogenesis, Clinical Impact and Management
https://libcat.nshealth.ca/en/permalink/provcat46491
Andrea R. Genazzani, Michelle Nisolle, Felice Petraglia, Robert N. Taylor, editors.
--Cham:
Springer
, c2021.
- Available Online
- View e-Book
- Access
- NEW Springer 2021
- Location
- Online
This volume focuses on endometriosis from its pathogenesis and the importance of the early diagnosis to treatment, throughout all aspects of femininity that this disease affects, impacting health and quality of life. It also covers treatment strategies for the pain and for the disease management according to the age and needs of the patient, from adolescence to menopause, passing through the fertile age and the consequences that this disease can have on fertility and pregnancy. This book is a u…
- Available Online
- View e-Book
- Responsibility
- Andrea R. Genazzani, Michelle Nisolle, Felice Petraglia, Robert N. Taylor, editors
- Place of Publication
- Cham
- Publisher
- Springer
- Date of Publication
- c2021
- Physical Description
- 1 online resource (viii, 166 p.) : 20 illus., 14 illus. in color
- ISBN
- 9783030578664
- 9783030578657 (Print ed.)
- 9783030578671 (Print ed.)
- 9783030578688 (Print ed.)
- ISSN
- 2197-8735
- Subjects (MeSH)
- Endometriosis - diagnosis
- Endometriosis - therapy
- Specialty
- Endocrinology
- Gynecology
- Abstract
- This volume focuses on endometriosis from its pathogenesis and the importance of the early diagnosis to treatment, throughout all aspects of femininity that this disease affects, impacting health and quality of life. It also covers treatment strategies for the pain and for the disease management according to the age and needs of the patient, from adolescence to menopause, passing through the fertile age and the consequences that this disease can have on fertility and pregnancy. This book is a useful, clear and up-to-date tool for gynecologists, gynecological surgeons, reproductive medicine and general practitioners and is an important source of information to face this more and more frequent and devastating disease.
- Contents
- 1. Endocrine disruptors and risk of endometriosis -- 2. Metabolomic characteristics in endometriosis patients -- 3. Can we diagnose early endometriosis with ultrasound rather than laparoscopy? -- 4. Neurotrophins and cytokines in endometriosis pain -- 5. Endometriosis induced pain: the treatment strategy -- 6. Management of endometriosis in teenagers -- 7. The etonogestrel contraceptive implant as a therapy for endometriosis -- 8. Impact of endometrioma surgery on ovarian reserve -- 9. What is the place of surgery of deep endometriosis in infertile and pelvic pain patients? -- 10. Endometriosis and Infertility: surgery and IVF: when, why and outcomes -- 11. ART and endometriosis : problems and solutions -- 12. Morphokinetics in embryos from patients with endometriosis -- 13. Endometriosis and cancer: prevention and diagnosis -- 14. Medical management of endometriosis, present and future with special reference to MHT in the patient previously diagnosed with endometriosis -- 15. Endometriosis and menopause: realities and management.
- Access
- NEW Springer 2021
- Format
- e-Book
- Location
- Online
Fundamentals of Male Infertility
https://libcat.nshealth.ca/en/permalink/provcat42620
Sherman Silber.
--Cham:
Springer
, c2018.
- Available Online
- View e-Book
- Location
- Online
This book analyzes the basic science and treatment of male factor infertility with Dr. Silber's characteristic honesty and clear thinking. It describes finally what works and what doesn't work. It will inspire everyone in reproductive medicine (Gynecologists, Urologists, Embryologists and Endocrinologists) who wish to better understand male infertility.
- Available Online
- View e-Book
- Author
- Silber, Sherman
- Responsibility
- Sherman Silber
- Place of Publication
- Cham
- Publisher
- Springer
- Date of Publication
- c2018
- Physical Description
- 1 online resource (xxix, 195 p.) : 142 illus., 93 illus. in color
- ISBN
- 9783319765235
- 9783319765228 (print ed.)
- 9783319765242 (print ed.)
- Subjects (MeSH)
- Infertility, Male - etiology
- Infertility, Male - therapy
- Reproductive Techniques, Assisted
- Testis - anatomy & histology
- Specialty
- Men's Health
- Reproductive Medicine
- Abstract
- This book analyzes the basic science and treatment of male factor infertility with Dr. Silber's characteristic honesty and clear thinking. It describes finally what works and what doesn't work. It will inspire everyone in reproductive medicine (Gynecologists, Urologists, Embryologists and Endocrinologists) who wish to better understand male infertility.
- Contents
- Part I. Basic Science of the Testis -- 1. Testis Development, Embryology, and Anatomy -- 2. Descent of the Fetal Testis from the Abdomen to the Scrotum -- 3. Adult Testis Anatomy -- 4. Structure of the Seminiferous Tubules -- 5. Blood Supply to the Testis -- 6. Histology of the Testis and Spermatogenesis -- 7. Hormonal Regulation of Spermatogenesis -- 8. Meiosis -- Part II. Evaluation and Treatment of Male Infertility -- 9. Evaluation of Male Infertility -- 10. Treatment of Male Infertility -- 11. Azoospermia -- 12. Karyotyping of Infertile Males and Their ICSI Offspring -- 13. Donor Sperm -- 14. Cryopreservation of Sperm -- 15. Varicocele -- 16. Kallman’s Syndrome and Hypopituitarism -- Part III. New Frontiers -- 17. The Genetic Control of Male Infertility and Understanding the Y Chromosome -- 18. Spermatogenic Stem Cell Cryopreservation and Transplantation -- 19. Making Sperm from Skin Cells -- 20. Identification of Spermatogonial Stem Cells and Genetic Control of All Stages of Spermatogenesis.
- Format
- e-Book
- Location
- Online
Genetics of Male Infertility : A Case-Based Guide for Clinicians
https://libcat.nshealth.ca/en/permalink/provcat45346
Mohamed Arafa, Haitham Elbardisi, Ahmad Majzoub, Ashok Agarwal, editors.
--Cham:
Springer
, c2020.
- Available Online
- View e-Book
- Location
- Online
This unique, case-based guide provides a thoughtful and comprehensive overview of the genetic basis of male infertility for the practicing clinician. In addition to discussing the molecular foundations of sperm production and the consequences of genetic abnormalities on various stages of sperm development, it examines the clinical aspects of acknowledged genetic disorders and their implications on male fertility. In so doing, it offers the necessary tools required by the clinician for the diagn…
- Available Online
- View e-Book
- Other Authors
- Arafa, Mohamed
- Elbardisi, Haitham
- Majzoub, Ahmad
- Agarwal, Ashok
- Responsibility
- Mohamed Arafa, Haitham Elbardisi, Ahmad Majzoub, Ashok Agarwal, editors
- Place of Publication
- Cham
- Publisher
- Springer
- Date of Publication
- c2020
- Physical Description
- 1 online resource (xvii, 375 p.) : 54 illus., 51 illus. in color
- ISBN
- 9783030379728
- 9783030379711 (Print ed.)
- 9783030379735 (Print ed.)
- 9783030379742 (Print ed.)
- Subjects (MeSH)
- Chromosome Aberrations
- Genetic Diseases, Inborn
- Infertility, Male - genetics
- Infertility, Male - physiopathology
- Abstract
- This unique, case-based guide provides a thoughtful and comprehensive overview of the genetic basis of male infertility for the practicing clinician. In addition to discussing the molecular foundations of sperm production and the consequences of genetic abnormalities on various stages of sperm development, it examines the clinical aspects of acknowledged genetic disorders and their implications on male fertility. In so doing, it offers the necessary tools required by the clinician for the diagnosis and treatment of infertile men with genetic abnormalities. Moreover, it provides essential algorithms that may aid in counseling patients in the clinic. The text is arranged in four thematic sections for easy reference. The genetic foundation of male reproduction is presented in part 1, including regulation of sperm production, the structure of sperm chromatin, and spermatogenesis. The impact of genetic abnormalities on male infertility is the subject of part 2, covering sperm defects, mitochondrial function and DNA fragmentation. The clinical case material in part 3 illustrates real-world examples of genetic etiologies and the current diagnostic and therapeutic strategies for conditions such as vas asplasia, cryptorchidism, immotile cilia syndrome, sperm aneuploidy and other challenging scenarios. Casting forward, the fourth and final section presents an overview of future possibilities for management of genetic causes of male infertility, including gene editing. Fully exploring the clinical context of these genetic conditions in a practical manner that appeals to the practicing clinician, Genetics of Male Infertility is an exciting and essential text for reproductive medicine specialists, andrologists, urologists, researchers and all other clinicians treating infertile patients.
- Contents
- Part I. The Genetic Basis of Reproduction -- The Molecular Genetics of Testis Determination -- Molecular Regulation of Sperm Production Cascade -- Spermatozoal Chromatin Structure: Role in Sperm Functions and Fertilization -- Genetic Basis of Endocrine Regulation of Spermatogenesis -- Epidemiology of Genetic Disorders in Male Infertility -- Genetic Evaluation of Male Infertility -- Part II. Impact of Genetics on the Sperm Cell -- Genetic Basis of Sperm Morphologic Defects: Head Defects, Body and Tail Defects -- Mitochondrial Function and Male Infertility -- Sperm DNA Fragmentation and Male Infertility -- The Sperm Epigenome and Potential Implications for the Developing Embryo -- Part III. Clinical Case Scenarios -- Klinefelter Syndrome -- Chromosomal Translocations and Inversion in Male Infertility -- Genetics of Vas Aplasia -- Anomalies of the Y Chromosome -- Infertility and Cryptorchidism -- Kartagener and Immotile Cilia Syndrome -- Persistent Müllerian Duct Syndrome -- Disorders of Sex Determination -- Endocrine Genetic Defects -- Sperm Aneuploidy -- Part IV. Genetic Infertility: Is There Any Hope? -- Sperm DNA Fragmentation -- The Potential of CRISPR/Cas Gene Editing to Correct Male Infertility.
- Format
- e-Book
- Location
- Online
Highlights from adoption as an alternative for infertile couples : prospects and trends
https://libcat.nshealth.ca/en/permalink/provcat53566
by Kerry J. Daly and Michael P. Sobol.
--Ottawa, ON:
Royal Commission on New Reproductive Technologies
, [1992?].
- Call Number
- WQ 205 DC2 R59ha 1992
- Location
- IWK Health Sciences Library
- Call Number
- WQ 205 DC2 R59ha 1992
- Author
- Daly, Kerry J.
- Corporate Author
- Canada. Royal Commission on New Reproductive Technologies
- Other Authors
- Sobol, Michael P.
- Responsibility
- by Kerry J. Daly and Michael P. Sobol
- Alternate Title
- Adoption as an alternative for infertile couples
- Place of Publication
- Ottawa, ON
- Publisher
- Royal Commission on New Reproductive Technologies
- Date of Publication
- [1992?]
- Physical Description
- [13] p. : ill.
- Subjects (MeSH)
- Adoption - trends
- Reproductive Techniques, Assisted - trends
- Infertility - trends
- Canada
- Format
- Book
- Location
- IWK Health Sciences Library
- Copies
- 1
- Loan Period
- 2 weeks
Human Gametes and Preimplantation Embryos : Assessment and Diagnosis
https://libcat.nshealth.ca/en/permalink/provcat40726
David K. Gardner, Denny Sakkas, Emre Seli, Dagan Wells, editors.
--New York, NY:
Springer
, c2013.
- Available Online
- View e-Book
- Location
- Online
In recent years, the advancing science and increasing availability of assisted reproduction have given new hope to infertile couples. However, the use of IVF and ART has also led to marked increases in the number of multiple-infant live births. This poses a public health concern, as these neonates have a higher rate of pre-term delivery, compromising their survival chances and increasing their risk of lifelong disability. By optimizing the selection of gametes and embryos with high probabilitie…
- Available Online
- View e-Book
- Other Authors
- Gardner, David K
- Sakkas, Denny
- Seli, Emre
- Wells, Dagan
- Responsibility
- David K. Gardner, Denny Sakkas, Emre Seli, Dagan Wells, editors
- Place of Publication
- New York, NY
- Publisher
- Springer
- Date of Publication
- c2013
- Physical Description
- 1 online resource (xv, 306 p. : 64 illus., 48 illus. in color)
- ISBN
- 9781461466512
- 9781461466505 (print ed.)
- Subjects (MeSH)
- Blastocyst
- Cell Survival
- Embryo Transfer
- Fertilization in Vitro
- Germ Cells - growth & development
- Preimplantation Diagnosis
- Reproductive Techniques, Assisted
- Abstract
- In recent years, the advancing science and increasing availability of assisted reproduction have given new hope to infertile couples. However, the use of IVF and ART has also led to marked increases in the number of multiple-infant live births. This poses a public health concern, as these neonates have a higher rate of pre-term delivery, compromising their survival chances and increasing their risk of lifelong disability. By optimizing the selection of gametes and embryos with high probabilities of implantation, it is possible to reduce the number of embryos transferred and, by extension, the number of high-risk multiple gestations, while maintaining or increasing pregnancy rates. Human Gametes and Preimplantation Embryos: Assessment and Diagnosis provides a broad yet concise overview of established and developing methodologies for assessment of gamete and embryo viability in assisted reproduction. This book elucidates the best practices for precisely selecting viable specimens based on morphology and cleavage rate and covers the spectrum of emerging adjunctive technologies for predicting reproductive potential. The authors present their extensive knowledge of "omics" approaches (genomics, transcriptomics, proteomics, and metabolomics), with unbiased delineation of the associated advantages and potential pitfalls. This valuable clinical resource is well suited to infertility specialists, Ob/Gyn physicians, IVF laboratory technicians, and researchers in the fields of embryology and reproductive medicine.
- Contents
- Current Practices and Regulations for Embryo Transfer Worldwide: Implications on IVF Outcome -- Analysis of the Zona Pellucida as an Indicator of Oocyte Developmental Potential -- Morphological Assessment of Oocytes, Pronuclear and Cleavage Stage Embryos -- Morphological Assessment of Blastocyst Stage Embryos: Types of Grading Systems and Their Reported Outcomes -- Real Time Imaging Strategies to Improve Morphological Assessment -- Limitations and Benefits of Morphologic Embryo Assessment Strategies: How Far Can Morphological Assessment Go in the Identification of Viable Embryos? -- Sperm Morphologic Characteristics and Their Impact on Embryo Quality and Pregnancy Outcome -- Objective Biomarkers of Sperm Development and Fertility: Assessment of Sperm-Zona Pellucida Binding Ability and Hyaluronic Acid Mediated Selection of Sperm for ICSI Fertilization -- Selecting the Best Sperm and Its Implications in Clinical Practice -- The Origins of Aneuploidy in Human Embryos -- Preimplantation Genetic Screening and Diagnosis Using Fluorescent In Situ Hybridization (FISH) -- Single Nucleotide Polymorphisms and Next Generation Sequencing -- Use of Comparative Genomic Hybridization (CGH) and Microarray-CGH for Preimplantation Genetic Screening -- Quantitative SNP Array and Real-Time PCR Based Human Preimplantation Embryo Aneuploidy Screening -- Regulation of Gene Expression in the Oocyte and Early Embryo: Implications for Transcriptomic and Proteomic Embryo Assessment -- Transcriptomics Technology: Promise and Potential Pitfalls -- Transcriptomic Analysis of Cumulus and Granulosa Cells as a Marker of Embryo Viability -- Mass Spectrometry, Proteomics and the Study of Sperm Cell Biology -- Proteomic Analysis of Embryo Viability -- Metabolism of the Viable Human Embryo -- Analysis of Respiration as an Indicator of Oocyte and Embryo Developmental Potential -- Mitochondrial Activity as a Biomarker of Gamete and Embryo Health -- Carbohydrate Analysis and Embryo Viability -- Identification of Viable Embryos by Non-invasive Measurement of Amino Acids in Culture Media -- Metabolomic Profiling of Embryos Using Spectroscopy -- Microfluidic Devices for the Analysis of Gamete and Embryo Physiology.
- Format
- e-Book
- Location
- Online
Infertility counseling : a comprehensive handbook for clinicians
https://libcat.nshealth.ca/en/permalink/provcat27272
edited by Sharon N. Covington, Linda Hammer Burns.
(2nd ed.)
--Cambridge, UK:
Cambridge University Press
, 2006.
- Available Online
- View e-Book
- Location
- Online
- Available Online
- View e-Book
- Author
- Covington, Sharon N
- Other Authors
- Burns, Linda Hammer
- Responsibility
- edited by Sharon N. Covington, Linda Hammer Burns
- Edition
- 2nd ed.
- Place of Publication
- Cambridge, UK
- Publisher
- Cambridge University Press
- Date of Publication
- 2006
- Physical Description
- xix, 658 p.
- ISBN
- 6610702527 (electronic bk.)
- Subjects (MeSH)
- Infertility - psychology
- Reproductive Techniques, Assisted - psychology
- Counseling - methods
- Contents
- Cover -- Half-title -- Title -- Copyright -- Dedication -- Contents -- List of Contributors -- Foreword -- Preface -- PART I. OVERVIEW -- 1 Psychology of Infertility -- HISTORICAL OVERVIEW -- REVIEW OF LITERATURE -- THEORETICAL FRAMEWORK -- CLINICAL ISSUES -- THERAPEUTIC INTERVENTIONS -- FUTURE IMPLICATIONS -- SUMMARY -- REFERENCES -- 2 Medical Aspects of Infertility for the Counselor -- HISTORICAL OVERVIEW -- REVIEW OF LITERATURE -- CLINICAL ISSUES -- THERAPEUTIC INTERVENTIONS -- FUTURE IMPLICATIONS -- SUMMARY -- REFERENCES -- 3 The Psychology of Gender-Specific Infertility Diagnoses -- HISTORICAL OVERVIEW -- REVIEW OF LITERATURE -- THEORETICAL FRAMEWORK -- CLINICAL ISSUES -- THERAPEUTIC INTERVENTIONS -- FUTURE IMPLICATIONS -- SUMMARY -- REFERENCES -- 4 Cross-Cultural Issues in Infertility Counseling -- The Need for Cultural Awareness -- HISTORICAL OVERVIEW -- REVIEW OF LITERATURE -- THEORETICAL FRAMEWORK -- CLINICAL ISSUES -- THERAPEUTIC INTERVENTIONS -- FUTURE IMPLICATIONS -- SUMMARY -- REFERENCES -- PART II. ASSESSMENT -- 5 Psychosocial Evaluation of the Infertile Patient -- INTRODUCTION -- HISTORICAL OVERVIEW -- REVIEW OF LITERATURE -- THEORETICAL FRAMEWORK -- CLINICAL ISSUES -- THERAPEUTIC INTERVENTIONS -- FUTURE IMPLICATIONS -- SUMMARY -- REFERENCES -- 6 Psychopathology and Psychopharmacology in the Infertile Patient -- HISTORICAL OVERVIEW -- REVIEW OF LITERATURE -- THEORETICAL FRAMEWORK -- CLINICAL ISSUES -- THERAPEUTIC INTERVENTIONS -- FUTURE IMPLICATIONS -- SUMMARY -- REFERENCES -- 7 Evidenced-Based Approaches to Infertility Counseling -- HISTORICAL OVERVIEW -- REVIEW OF LITERATURE -- THEORETICAL FRAMEWORKS -- CLINICAL ISSUES -- THERAPEUTIC INTERVENTION -- FUTURE IMPLICATIONS -- SUMMARY -- REFERENCES -- PART III. TREATMENT MODALITIES -- 8 Individual Counseling and Psychotherapy -- HISTORICAL OVERVIEW -- REVIEW OF LITERATURE -- THEORETICAL FRAMEWORKS -- CLINICAL ISSUES -- THERAPEUTIC INTERVENTIONS -- FUTURE IMPLICATIONS -- SUMMARY -- REFERENCES -- 9 Counseling the Infertile Couple -- HISTORICAL OVERVIEW -- THEORETICAL FRAMEWORKS -- REVIEW OF LITERATURE -- CLINICAL ISSUES -- THERAPEUTIC INTERVENTION -- FUTURE IMPLICATIONS -- SUMMARY -- REFERENCES -- 10 Group Approaches to Infertility Counseling -- HISTORICAL OVERVIEW -- REVIEW OF LITERATURE -- THEORETICAL FRAMEWORK -- CLINICAL ISSUES -- THERAPEUTIC INTERVENTION -- FUTURE IMPLICATONS -- SUMMARY -- REFERENCES -- 11 Behavioral Medicine Approaches to Infertility Counseling -- HISTORICAL OVERVIEW -- REVIEW OF LITERATURE -- THEORETICAL FRAMEWORK -- CLINICAL ISSUES -- THERAPEUTIC INTERVENTIONS -- FUTURE IMPLICATIONS -- SUMMARY -- REFERENCES -- 12 Complementary and Alternative Medicine in Infertility Counseling -- HISTORICAL OVERVIEW -- LITERATURE REVIEW -- THEORETICAL FRAMEWORK -- CLINICAL ISSUES -- THERAPEUTIC INTERVENTIONS -- FUTURE IMPLICATIONS -- SUMMARY -- REFERENCES -- 13 Sexual Counseling and Infertility -- HISTORICAL OVERVIEW -- REVIEW OF LITERATURE -- THEORETICAL FRAMEWORK -- CLINICAL ISSUES -- THERAPEUTIC INTERVENTIONS -- FUTURE IMPLICATIONS -- S
- Format
- e-Book
- Location
- Online
Infertility in Women with Polycystic Ovary Syndrome : Pathogenesis and Management
https://libcat.nshealth.ca/en/permalink/provcat43318
Stefano Palomba, editor.
--Cham:
Springer
, c2018.
- Available Online
- View e-Book
- Location
- Online
This book presents up-to-date knowledge on infertility in the context of polycystic ovary syndrome (PCOS) and provides clear evidence-based guidance on its treatment. The book opens by discussing anovulation, oocyte quality, and the endometrium in women with PCOS, infertility and subfertility cofactors, and the impact of PCOS phenotypes on fertility. All aspects of management are then thoroughly addressed. The available medical treatments for PCOS-related infertility—including antiestrogens, ar…
- Available Online
- View e-Book
- Other Authors
- Palomba, Stefano
- Responsibility
- Stefano Palomba, editor
- Place of Publication
- Cham
- Publisher
- Springer
- Date of Publication
- c2018
- Physical Description
- 1 online resource (xiii, 337 p.) : 40 illus., 28 illus. in color
- ISBN
- 9783319455341
- 9783319455334 (print ed.)
- 9783319455358 (print ed.)
- 9783319833149 (print ed.)
- Subjects (MeSH)
- Infertility, Female - therapy
- Polycystic Ovary Syndrome - complications
- Polycystic Ovary Syndrome - diagnosis
- Polycystic Ovary Syndrome - therapy
- Specialty
- Gynecology
- Reproductive Medicine
- Abstract
- This book presents up-to-date knowledge on infertility in the context of polycystic ovary syndrome (PCOS) and provides clear evidence-based guidance on its treatment. The book opens by discussing anovulation, oocyte quality, and the endometrium in women with PCOS, infertility and subfertility cofactors, and the impact of PCOS phenotypes on fertility. All aspects of management are then thoroughly addressed. The available medical treatments for PCOS-related infertility—including antiestrogens, aromatase inhibitors, insulin-sensitizing drugs, and gonadotropins—are reviewed, and other potential therapeutic approaches, such as acupuncture and laparoscopic ovarian drilling, are assessed. Careful attention is also devoted to the role of lifestyle interventions. The use of controlled ovarian stimulation in infertile PCOS patients undergoing intrauterine insemination or in vitro fertilization is examined in detail, as are the benefits of in vitro maturation of oocytes. This book will be of value to all who are involved in the care of women with PCOS and related infertility issues.
- Contents
- Part I. Diagnosis, Pathophysiology, and Pathogenesis -- 1. Introduction -- 2. Diagnostic Criteria for PCOS -- 3. Anovulation in Women with PCOS -- 4. Oocyte Quality in PCOS -- 5. Endometrial Receptivity in PCOS -- 6. Infertility and Subfertility Cofactors in Women with PCOS -- 7. PCOS Phenotypes: Impact on Fertility -- 8. Follicle Excess and Abnormalities in Women with PCOS: Pathophysiology, Assessment and Clinical Role -- Part II. Medical Treatments -- 9. Antiestrogens -- 10. Aromatase Inhibitors - 11. Insulin-Sensitising Drugs -- 12. Gonadotrophins -- Part III. Lifestyle Management and Other Treatment Approaches -- 13. Lifestyle Interventions and Natural and Assisted Reproduction in Patients with PCOS -- 14. Dietary Supplements, Phytotherapy and Chinese Herbal Medicine in PCOS -- 15. Laparoscopic Ovarian Drilling -- 16. Inositols -- 17. Acupuncture -- Part IV. Controlled Ovarian Stimulation and In Vitro Oocyte Maturation -- 18. Intrauterine Insemination -- 19. Controlled Ovarian Stimulation for In Vitro Fertilisation Cycles -- 20. In Vitro Oocyte Maturation -- Part V. Integrated Strategies, Complications of Pregnancy, and Outlook -- 21. Integrated Strategies for Enhancement of Fertility in PCOS -- 22. Complications of Pregnancy -- 23. Conclusive Remarks and Future Perspectives.
- Format
- e-Book
- Location
- Online
In Vitro Fertilization : A Comprehensive Guide
https://libcat.nshealth.ca/en/permalink/provcat30868
Elizabeth S. Ginsburg, Catherine Racowsky, editors.
--New York, NY:
Springer
, c2012.
- Available Online
- View e-Book
- Location
- Online
In Vitro Fertilization: A Comprehensive Guide represents the next frontier in the integrated clinical and laboratory practice of ART. Uniquely balanced, the book provides the necessary understanding of the key laboratory techniques involved in ART and the complex aspects of clinical care. Featuring the contributions of world leaders in the field, the guide begins with the evaluation of the infertile woman and man. It then moves on to discuss treatment protocols and adjunctive treatments. Techni…
- Available Online
- View e-Book
- Other Authors
- Ginsburg, Elizabeth S
- Racowsky, Catherine
- Responsibility
- Elizabeth S. Ginsburg, Catherine Racowsky, editors
- Place of Publication
- New York, NY
- Publisher
- Springer
- Date of Publication
- c2012
- Physical Description
- 1 online resource (xiii, 272 p. : 64 ill., 49 ill. in color)
- ISBN
- 9781441998484
- Subjects (MeSH)
- Fertilization in Vitro
- Reproductive Techniques, Assisted
- Subjects (LCSH)
- Gynecology
- Obstetrics
- Reproductive medicine
- Abstract
- In Vitro Fertilization: A Comprehensive Guide represents the next frontier in the integrated clinical and laboratory practice of ART. Uniquely balanced, the book provides the necessary understanding of the key laboratory techniques involved in ART and the complex aspects of clinical care. Featuring the contributions of world leaders in the field, the guide begins with the evaluation of the infertile woman and man. It then moves on to discuss treatment protocols and adjunctive treatments. Techniques for oocyte retrieval and insemination, embryo culture and transfer, and micromanipulation procedures are explored in detail. This comprehensive book covers all aspects of IVF and includes special sections on oocyte and embryo donation as well as gestational carriers, making it ideal for practicing clinicians. Advances such as pre-implantation genetic diagnosis and screening, in vitro maturation, and means of fertility preservation, including oocyte and ovarian tissue cryopreservation, are also covered. The book concludes with dedicated chapters on quality assessment and improvement, regulation and legal concerns, and stress and ART. Readers will gain complete in-depth knowledge of the most current therapies and techniques, enabling optimal care and counsel of their infertile patients.
- Contents
- Pre IVF Evaluation of the Infertile Woman -- Pre IVF Evaluation of the Infertile Man -- Ovarian Stimulation and Cycle Management in IVF -- Oocyte Retrieval and Embryo Transfer -- Moving Toward Single Embryo Transfer -- Oocyte Insemination and Culture -- Micromanipulation: Intracytoplasmic Sperm Injection and Assisted Hatching -- Preimplantation Genetic Testing -- Embryo Cryopreservation -- Oocyte Donation -- Gestational Carrier -- Adjunctive Treatments in ART -- Stress and ART -- Fertility Preservation -- Ongoing Quality Assessment/ Improvement in Clinical IVF -- Regulation and Legal Concerns in IVF.
- Format
- e-Book
- Location
- Online
Male Infertility : Contemporary Clinical Approaches, Andrology, ART and Antioxidants
https://libcat.nshealth.ca/en/permalink/provcat44821
Sijo J. Parekattil, Sandro C. Esteves, Ashok Agarwal, editors.
(Second edition)
--Cham:
Springer
, c2020.
- Available Online
- View e-Book
- Location
- Online
A groundbreaking contribution to the literature now in its revised and expanded second edition, this textbook offers a comprehensive review of diagnostic and treatment techniques for male infertility. This state-of-the-art, evidence-based textbook incorporates new multidisciplinary and complementary medicine approaches to create a first-of-its-kind guide to treatment strategies for male infertility and beyond. While this new edition is primarily designed as a reference for students and resident…
- Available Online
- View e-Book
- Other Authors
- Parekattil, Sijo J.
- Esteves, Sandro C.
- Agarwal, Ashok
- Responsibility
- Sijo J. Parekattil, Sandro C. Esteves, Ashok Agarwal, editors
- Edition
- Second edition
- Place of Publication
- Cham
- Publisher
- Springer
- Date of Publication
- c2020
- Physical Description
- 1 online resource (xxvii, 914 p.) : 213 illus., 182 illus. in color
- ISBN
- 9783030323004
- 9783030322991 (Print ed.)
- 9783030323011 (Print ed.)
- 9783030323028 (Print ed.)
- Subjects (MeSH)
- Andrology - methods
- Infertility, Male
- Reproductive Techniques, Assisted
- Specialty
- Men's Health
- Reproductive Medicine
- Abstract
- A groundbreaking contribution to the literature now in its revised and expanded second edition, this textbook offers a comprehensive review of diagnostic and treatment techniques for male infertility. This state-of-the-art, evidence-based textbook incorporates new multidisciplinary and complementary medicine approaches to create a first-of-its-kind guide to treatment strategies for male infertility and beyond. While this new edition is primarily designed as a reference for students and residents in reproductive medicine and andrology, it will be equally useful as well for professionals in urology, reproductive endocrinology, embryology, and research fields who are interested in the role that antioxidants play in male infertility. World-renowned experts in these areas have been selected to participate in this work. Careful selection of the highest quality content will span the whole range of topics in the area of male infertility, providing a complete review of well-established and current diagnostic and treatment techniques for male infertility. The incorporation of 20 new chapters will enhance the book’s appeal by including the most recent advances brought to the male infertility arena. Additionally, this edition incorporates new features, including bulleted key points, review criteria and select video clips demonstrating some of the most fascinating male infertility treatment modalities. A dedicated new section on current guidelines on male infertility will enlighten readers on how to most optimally manage male infertility clinical scenarios. Covering all aspects of diagnosis and management, ART, lifestyle factors and associated conditions for male infertility, Male Infertility: Contemporary Clinical Approaches, Andrology, ART and Antioxidants will be a readily accessible, high quality reference for medical students and residents, and will be of significant value to professionals working in the various fields treating this condition as well.
- Contents
- Part I. Male Infertility Diagnosis and Management -- Causes of Male Infertility -- Epidemiologic Considerations in Male Infertility -- Laboratory Evidence for Male Infertility -- Imaging Modalities in the Management of Male Infertility -- Endocrinopathies -- Oxidative Stress and its Association with Male Infertility -- Oxidative Stress Measurement in Semen and Seminal Plasma -- Sperm Chromatin Integrity Tests and Indications -- Proteomic and Metabolomic Fingerprinting in Male Infertility -- Epigenetics and Male Infertility -- Genetic Aspects of Male Infertility -- Surgical Treatment for Male Infertility -- Microsurgery for Male Infertility -- Advanced Techniques of Vasoepididymostomy -- Grafting Techniques for Vasectomy Reversal -- Mini-Incision Vasectomy Reversal Using the No-Scalpel Vasectomy Instruments and Principles -- Office-Based Microsurgery under Local Anesthesia for Male Infertility -- Robotic Microsurgery for Male Infertility and Chronic Orchialgia -- Robotic Vasectomy Reversal: An American Perspective -- Robot-Assisted Vasectomy Reversal (Vasovasostomy) -- Robotic-Assisted Varicocelectomy -- Management of Fertility Preservation in Male Cancer Patients -- Clinical Management of Men with Nonobstructive Azoospemia due to Spermatogenic Failure -- ART and Its Impact on Male Infertility Management -- Part II. Sperm Physiology and Metabolism -- Fuel/energy sources of spermatozoa -- Physiologic Role of ROS in Sperm Function -- Sperm physiology and assessment of spermatogenesis kinetics in vivo -- Origins of Sperm DNA Damage -- Seminal Oxidation-Reduction Potential -- Part III. Common Conditions and Factors Affecting Male Reproductive Health -- Varicocele -- Infection in Infertility -- Ejaculatory Dusfunction and Vasodynamics -- Environmental Factors -- Effect of Exogenous Medications and Anabolic Steroids in Male Reproductive and Sexual Health -- Male Age and Andropause -- Apoptosis and Male Infertility -- Impact of Spinal Cord Injury -- Obesity -- Smoking effects on male fertility -- Recreational Drugs -- Part IV. Nutrition, Life-Style and Antioxidants Role for Male Reproductive Health -- Nutritional Pathways to Protect Male Reproductive Health -- Antioxidants and Male Infertility -- Synthetic Antioxidants -- New developments for the Enhancement of Male Reproductive Health using Antioxidant Therapy: A Critical Review of the Literature -- In Vitro Studies of Antioxidants for Male Reproductive Health -- Antioxidants Use and Sperm DNA Damage -- Yoga, Meditation and Acupuncture for Male Reproductive Health -- Part V. Assisted Reproductive Technology in Male Fertility -- Role of interventions to reduce oxidative stress and improve sperm DNA integrity before ICSI -- Sperm Retrieval Techniques -- Microdissection Testicular Sperm Extraction -- Sperm Processing and Selection -- Microfluidic sperm selection -- Antioxidants in Sperm Cryopreservation -- Antioxidants in ICSI -- Role of Sperm-Hyaluronic Acid Binding in the Evaluation and Treatment of Subfertile Men with ROS-Affected Semen -- Sperm DNA Damage, ART Outcomes and Laboratory Methods for Selecting DNA-Intact Sperm for ICSI -- Testicular Sperm in Non-Azoospermic Infertile Men with Oxidatively-Induced High Sperm DNA Damage -- Development of Artificial Gametes -- ICSI and Male Infertility: Consequences to Offspring -- Part VI. Guidelines and Best Practices in Male Infertility and Antioxidants -- Best Practice Guidelines for Male Infertility Diagnosis and Management -- Best Practice Guidelines for Sperm DNA Fragmentation Testing -- Antioxidants in the medical and surgical management of male infertility -- Part VII. Special Topics -- Fertility Preservation for Boys and Adolescents -- Novel Home-based Devices for Male Infertility Screening -- Ethical Dimensions of Male Infertility -- Harmful Effects of Antioxidant Therapy -- Male Infertility from the Developing Nation Perspective -- Diabetes and Male Infertility -- Empiric Medical Therapy for Idiopathic Male Infertility -- Testosterone Therapy in Male Infertility.
- Format
- e-Book
- Location
- Online
Manual of Fertility Enhancing Hysteroscopy
https://libcat.nshealth.ca/en/permalink/provcat42901
edited by Shikha Jain, Dattaprasad B. Inamdar.
--Singapore:
Springer
, c2018.
- Available Online
- View e-Book
- Location
- Online
This book is an illustrated yet comprehensive compilation by experts in the field of fertility enhancing endoscopic surgery and assisted reproduction. This book catalogues full spectrum of diagnostic and operative hysteroscopy in the infertile population. The authors describe different techniques in various clinical conditions and review the recent evidence based literature supporting them. All procedures are explained in clear and precise text supplemented with high quality color pictures.
- Available Online
- View e-Book
- Other Authors
- Jain, Shikha
- Inamdar, Dattaprasad B.
- Responsibility
- edited by Shikha Jain, Dattaprasad B. Inamdar
- Place of Publication
- Singapore
- Publisher
- Springer
- Date of Publication
- c2018
- Physical Description
- 1 online resource (xvi, 202 p.) : 90 illus., 84 illus. in color
- ISBN
- 9789811080289
- 9789811080272 (print ed.)
- 9789811080296 (print ed.)
- Subjects (MeSH)
- Hysteroscopy - methods
- Infertility, Female - surgery
- Reproductive Techniques, Assisted
- Specialty
- Endoscopy
- Reproductive Medicine
- Abstract
- This book is an illustrated yet comprehensive compilation by experts in the field of fertility enhancing endoscopic surgery and assisted reproduction. This book catalogues full spectrum of diagnostic and operative hysteroscopy in the infertile population. The authors describe different techniques in various clinical conditions and review the recent evidence based literature supporting them. All procedures are explained in clear and precise text supplemented with high quality color pictures.
- Contents
- 1. Introduction and general principles of hysteroscopy -- 2. Anaesthesia for hyteroscopy -- 3. Indications and contraindications of hysteroscopy -- 4. Hysteroscopy and fertility -- 5. Polyps: Hysteroscopic diagnosis & management -- 6. Hysteroscopic myomectomy -- 7. Hysteroscopy in mullerian anomalies -- 8. Asherman syndrome and hysteroscopy -- 9. Role of hysteroscopy in ART -- 10. Hysteroscopy in tubal disease -- 11. Hysteroscopy in endometrial tuberculosis -- 12. Complications of hysteroscopy -- 13. Newer developments and future applications of hysteroscopy in infertility.
- Format
- e-Book
- Location
- Online
Men's Health
https://libcat.nshealth.ca/en/permalink/provcat32356
Peter H.C. Lim, editor.
--London:
Springer
, c2013.
- Available Online
- View e-Book
- Location
- Online
Men's Health is a concise, didactic compendium that covers three important aspects of male sexual health: Testosterone Deficiency Syndrome; Premature Ejaculation and Sexually Transmitted Infections (STIs). The chapters that deal with Testosterone Deficiency Syndrome cover the epidemiology of the condition in the local context, the science behind the condition, its clinical presentation and treatment choices. The section on Premature Ejaculation advises the health practitioner on how to invest…
- Available Online
- View e-Book
- Other Authors
- Lim, Peter H.C
- Responsibility
- Peter H.C. Lim, editor
- Place of Publication
- London
- Publisher
- Springer
- Date of Publication
- c2013
- Physical Description
- 1 online resource (xviii, 204 p. : 46 ill., 41 ill. in color)
- ISBN
- 9781447147664
- Subjects (MeSH)
- Hypogonadism
- Premature Ejaculation
- Sexually Transmitted Diseases
- Men's Health
- Reproductive Health
- Sexual Dysfunction, Physiological
- Subjects (LCSH)
- Endocrinology
- Infectious diseases
- Reproductive medicine
- Urology
- Abstract
- Men's Health is a concise, didactic compendium that covers three important aspects of male sexual health: Testosterone Deficiency Syndrome; Premature Ejaculation and Sexually Transmitted Infections (STIs). The chapters that deal with Testosterone Deficiency Syndrome cover the epidemiology of the condition in the local context, the science behind the condition, its clinical presentation and treatment choices. The section on Premature Ejaculation advises the health practitioner on how to investigate this condition and describes the various treatment options available to the patient. The chapters on Sexually Transmitted Infections cover special aspects of the diagnosis, prevention and treatment of STIs occurring in Men which are not normally highlighted in the usual texts on STI management. Written by experts in the field, Men's Health is a valuable and timely resource for urologists, andrologists, endocrinologists as well as other health professionals practicing in these areas.
- Contents
- Part I: Hypogonadism -- 1. Epidemiology: Late-Onset Hypogonadism in Singapore -- 2. Pathophysiology of Late-Onset Hypogonadism and Risks and Benefits of Replacement Therapy -- 3. Testosterone Assays and Their Potential Pitfalls -- 4. Diagnosing and Evaluating Androgen Deficiency, Including Andropause -- 5. Testosterone Preparations for Treatment of Hypogonadal Men -- 6. Androgens, Use, Misuse, and Abuse -- 7. Testosterone Therapy, Prostate Safety, and Other Safety Issues -- 8. The Role of Testosterone in the Metabolic Syndrome in Men -- 9. The Testosterone and ED (or Sexual Function) Connection -- 10. Treating Hypogonadism Associated with Erectile Dysfunction -- 11. Traditional Asian Herbs: Potential Use for Late-Onset Hypogonadism? -- 12. Effects of Excessive Androgen Use and Abuse -- 13. Practice Pointers for the Practitioner -- 14. Collection Charts/Questionnaires/Testosterone Calculators/Other Aide-Memoires, etc. for the GP -- Part II:Premature Ejaculation -- 15. Introduction -- 16. Etiology of Premature Ejaculation -- 17. Initial Workup and Use of Assessment Tools -- 18. Initial Management of the Newly Diagnosed PE -- 19. Premature Ejaculation: Simple Behavioral Therapy Steps -- 20. Choice of Pharmacologic Agents -- 21. Premature Ejaculation: Treatment of the Difficult Case and Advanced Counseling Techniques and When to Refer -- 22. Management of the Infertile Couple When the Male Partner Has Ejaculatory Dysfunction -- 23. Delayed/Retarded Ejaculation -- 24. Collection of Bedside Aids for Diagnosis and Tools for Assessment of Treatment to Goal -- 25. Frequently Asked Questions on Dapoxetine (FAQ’S) -- Part III: Sexually Transmitted Infections -- 26. Overview -- 27. HIV/AIDS -- 28. Breaking the News and Counseling -- 29. Prostatitis in Men -- 30. STIs, Depression and Sexual Dysfunction -- 31. Guidelines: Making the Diagnosis and Managing the Partner -- Index .
- Format
- e-Book
- Location
- Online
Men's sexual health and fertility : a clinician's guide
https://libcat.nshealth.ca/en/permalink/provcat33594
John P. Mulhall, Wayland Hsiao, editors.
--New York:
Springer
, c2014.
- Available Online
- View e-Book
- Location
- Online
In the last decade, much of the clinical interest in the field of infertility has focused on advancing reproductive techniques and has often under-appreciated the role that male sexuality plays in reproductive problems. Male sexual function is an integral part of reproduction, and the treatment of sexual dysfunction is an important component for any couple seeking fertility. In some cases, treatment of sexual dysfunction may obviate the need for more invasive cures through advanced reproductive…
- Available Online
- View e-Book
- Other Authors
- Mulhall, John P
- Hsiao, Wayland
- Responsibility
- John P. Mulhall, Wayland Hsiao, editors
- Place of Publication
- New York
- Publisher
- Springer
- Date of Publication
- c2014
- Physical Description
- 1 online resource (xiii, 268 pages)
- ISBN
- 9781493904259 (electronic bk.)
- 9781493904242
- Subjects (MeSH)
- Infertility, male
- Men's Health
- Reproductive Health
- Subjects (LCSH)
- Male reproductive health
- Fertility, Human
- Abstract
- In the last decade, much of the clinical interest in the field of infertility has focused on advancing reproductive techniques and has often under-appreciated the role that male sexuality plays in reproductive problems. Male sexual function is an integral part of reproduction, and the treatment of sexual dysfunction is an important component for any couple seeking fertility. In some cases, treatment of sexual dysfunction may obviate the need for more invasive cures through advanced reproductive techniques. Thanks to recent clinical and scientific advances in male sexual medicine, the management of men's sexual dysfunction is often more effective and less invasive than how it was historically described. Men's Sexual Health and Fertility is the only resource that focuses on the interplay and interconnections between male sexual dysfunction and male factor infertility, gathering insightful data from a panel of experts in male sexual medicine for clinicians who treat couples with fertility issues due to male sexual dysfunction. Chapters discuss advances in the field of men's sexual medicine, including the latest treatment for erectile dysfunction, the most up-to-date understanding of the physiology and pathophysiology of ejaculation, and the growing body of evidence that low testosterone and male infertility are intimately related. As such, this book provides important information in order to be able to better understand the link between sexual dysfunction and infertility and, most importantly, to better treat male sexual dysfunction in the infertile couple.
- Contents
- Physiology of Erection -- Physiology of Ejaculation -- Physiology of Testosterone Production -- The Effects of Vaginal Lubricants on Sperm Function -- Sexually Transmitted Infections -- Erectile Dysfunction and Infertility -- Anejaculation, Retrograde Ejaculation, and Anorgasmia -- Premature Ejaculation -- Delayed Ejaculation and Orgasm -- Hypogonadism and Infertility -- Varicoceles and Hypogonadism -- Nutraceuticals for Fertility and Erectile Health: A Brief Overview of What Works and What Is Worthless -- Effects of Phosphodiesterase-5 Inhibitors on Testicular and Sperm Function -- Circumcision and Vasectomy: Do They Affect Sexual Function?
- Format
- e-Book
- Location
- Online
