The Ethics of Screening in Health Care and Medicine : Serving Society or Serving the Patient?
https://libcat.nshealth.ca/en/permalink/provcat40880
Niklas Juth, Christian Munthe.
--Dordrecht:
Springer
, c2012.
- Available Online
- View e-Book
- Location
- Online
Medical or health-oriented screening programs are amongst the most debated aspects of health care and public health practices in health care and public health ethics, as well as health policy discussions. In spite of this, most treatments of screening in the research literature restrict themselves to isolated scientific aspects, sometimes complemented by economic analyses or loose speculations regarding policy aspects. At the same time, recent advances in medical genetics and technology, as wel…
- Available Online
- View e-Book
- Author
- Juth, Niklas
- Other Authors
- Munthe, Christian
- Responsibility
- Niklas Juth, Christian Munthe
- Place of Publication
- Dordrecht
- Publisher
- Springer
- Date of Publication
- c2012
- Physical Description
- 1 online resource (x, 180 p.)
- Series Vol.
- v. 51
- ISBN
- 9789400720459
- 9789400720442 (print ed.)
- ISSN
- 1567-8008
- Subjects (MeSH)
- Mass Screening - ethics
- Abstract
- Medical or health-oriented screening programs are amongst the most debated aspects of health care and public health practices in health care and public health ethics, as well as health policy discussions. In spite of this, most treatments of screening in the research literature restrict themselves to isolated scientific aspects, sometimes complemented by economic analyses or loose speculations regarding policy aspects. At the same time, recent advances in medical genetics and technology, as well as a rapidly growing societal focus on public health concerns, inspires an increase in suggested or recently started screening programs. This book involves an in-depth analysis of the ethical, political and philosophical issues related to health-oriented screening programs. It explores the considerations that arise when heath care interacts with other societal institutions on a large scale, as is the case with screening: What values may be promoted or compromised by screening programs? What conflicts of values do typically arise--both internally and in relation to the goals of health care, on the one hand, and the goals of public health and the general society, on the other? What aspects of screening are relevant for determining whether it should be undertaken or not and how it should be organised in order to remain defensible? What implications does the ethics of screening have for health care ethics as a whole? These questions are addressed by applying philosophical methods of conceptual analysis, as well as models and theories from moral and political philosophy, medical ethics, and public health ethics, to a large number of ongoing and proposed screening programs which makes this book the first comprehensive work on the ethics of screening. Analyses and suggestions are made that are of potential interest to health care staff, medical researchers, policy makers and the general public.
- Contents
- 1. Introduction -- 2. Why Screening? -- 3. Screening: What, When and Whom? -- 4. Screening: How? -- 5. Case Studies -- 6. Serving Society or Serving the Patient?
- Format
- e-Book
- Location
- Online
HBR's 10 must reads : on change
https://libcat.nshealth.ca/en/permalink/provcat26315
Harvard Business Review.
--Boston, MA:
Harvard Business Review Press
, c2011.
- Call Number
- HD 58.8 H394 2011
- Location
- Halifax Infirmary
Most company's change initiatives fail. Yours don't have to. This title includes "Harvard Business Review" articles that inspires you to: lead change through eight critical stages; establish a sense of urgency; overcome addiction to the status quo; mobilize commitment; silence naysayers; minimize the pain of change; and, concentrate resources.
- Call Number
- HD 58.8 H394 2011
- Corporate Author
- Harvard Business Review
- Responsibility
- Harvard Business Review
- Alternate Title
- Harvard Business Review's ten must reads
- On change
- Place of Publication
- Boston, MA
- Publisher
- Harvard Business Review Press
- Date of Publication
- c2011
- Physical Description
- 210 p.
- Series Title
- HBR's 10 must reads
- ISBN
- 9781422152005
- Subjects (MeSH)
- Leadership
- Organizational Innovation
- Abstract
- Most company's change initiatives fail. Yours don't have to. This title includes "Harvard Business Review" articles that inspires you to: lead change through eight critical stages; establish a sense of urgency; overcome addiction to the status quo; mobilize commitment; silence naysayers; minimize the pain of change; and, concentrate resources.
- Format
- Book
- Location
- Halifax Infirmary
- Copies
- 1
- Loan Period
- 3 weeks
Innovations for Next-Generation Antibody-Drug Conjugates
https://libcat.nshealth.ca/en/permalink/provcat43016
Marc Damelin, editor.
--Cham:
Humana Press
, c2018.
- Available Online
- View e-Book
- Location
- Online
Antibody-drug conjugates (ADCs) stand at the verge of a transformation. Scores of clinical programs have yielded only a few regulatory approvals, but a wave of technological innovation now empowers us to overcome past technical challenges. This volume focuses on the next generation of ADCs and the innovations that will enable them. The book inspires the future by integrating the field's history with novel strategies and cutting-edge technologies. While the book primarily addresses ADCs for soli…
- Available Online
- View e-Book
- Other Authors
- Damelin, Marc
- Responsibility
- Marc Damelin, editor
- Place of Publication
- Cham
- Publisher
- Humana Press
- Date of Publication
- c2018
- Physical Description
- 1 online resource (viii, 357 p.) : 70 illus., 52 illus. in color
- Series Title
- Cancer drug discovery and development
- ISBN
- 9783319781549
- 9783319781532 (print ed.)
- 9783319781556 (print ed.)
- ISSN
- 2196-9906
- Subjects (MeSH)
- Antineoplastic Agents - pharmacology
- Drug Design
- Immunoconjugates
- Molecular Targeted Therapy
- Neoplasms - drug therapy
- Specialty
- Medical Oncology
- Pharmacology
- Abstract
- Antibody-drug conjugates (ADCs) stand at the verge of a transformation. Scores of clinical programs have yielded only a few regulatory approvals, but a wave of technological innovation now empowers us to overcome past technical challenges. This volume focuses on the next generation of ADCs and the innovations that will enable them. The book inspires the future by integrating the field's history with novel strategies and cutting-edge technologies. While the book primarily addresses ADCs for solid tumors, the last chapter explores the emerging interest in using ADCs to treat other diseases. The therapeutic rationale of ADCs is strong: to direct small molecules to the desired site of action (and away from normal tissues) by conjugation to antibodies or other targeting moieties. However, the combination of small and large molecules imposes deep complexity to lead optimization, pharmacokinetics, toxicology, analytics and manufacturing. The field has made significant advances in all of these areas by improving target selection, ADC design, manufacturing methods and clinical strategies. These innovations will inspire and educate scientists who are designing next-generation ADCs with the potential to transform the lives of patients.
- Contents
- 1. Introduction: Motivations for Next-Generation ADCs -- 2. Combining ADCs with Immuno-oncology Agents -- 3. Improving the Safety Profile of ADCs -- 4. Utility of PK-PD Modeling and Simulation to Improve Decision Making for Antibody-Drug Conjugate Development -- 5. Regulatory Considerations and Companion Diagnostics -- 6. ADC Process Development and Manufacturing -- 7. HER2-Targeted ADCs: At the Forefront of ADC Technology Development -- 8. Next Generation Payloads for ADCs -- 9. Delivering More Payload: High DAR ADCs -- 10. Site-Specific Antibody Drug Conjugates -- 11. Bispecific and Biparatopic Antibody-Drug Conjugates -- 12. Drug Conjugates to the Tumor Microenvironment: Probody Drug Conjugates -- 13. Antibody-Drug Conjugates: Targeting the Tumor Microenvironment -- 14. Next Horizons: ADCs Beyond Oncology.
- Format
- e-Book
- Location
- Online
The Leader : Psychological Essays
https://libcat.nshealth.ca/en/permalink/provcat40894
Charles B. Strozier, Daniel Offer, Oliger Abdyli, editors.
--New York, NY:
Springer
, c2011.
- Available Online
- View e-Book
- Location
- Online
Behind every leader is an instructive life story. It often promotes a public image that inspires others to live by it. And, sometimes, even to live or to die for it. As leadership qualities and image issues gain significance in the public discourse, the psychological study of leadership is a critical factor in any discussion. With its trenchant insights into leaders past and present, The Leader: Psychological Essays, Second Edition, updates a pioneering text in this field and provides a solid b…
- Available Online
- View e-Book
- Other Authors
- Strozier, Charles B
- Offer, Daniel
- Abdyli, Oliger
- Responsibility
- Charles B. Strozier, Daniel Offer, Oliger Abdyli, editors
- Place of Publication
- New York, NY
- Publisher
- Springer
- Date of Publication
- c2011
- Physical Description
- 1 online resource (xviii, 179 p.)
- ISBN
- 9781441983879
- 9781441983855 (print ed.)
- Subjects (MeSH)
- Leadership
- Abstract
- Behind every leader is an instructive life story. It often promotes a public image that inspires others to live by it. And, sometimes, even to live or to die for it. As leadership qualities and image issues gain significance in the public discourse, the psychological study of leadership is a critical factor in any discussion. With its trenchant insights into leaders past and present, The Leader: Psychological Essays, Second Edition, updates a pioneering text in this field and provides a solid basis for ongoing dialogue on this important subject. Within the context of the ever-evolving disciplines of psychoanalysis and psychodynamics, this thought-provoking volume examines the lives of several prominent leaders from ancient Greece through the start of the 21st century. The authors explore how these leaders imposed their individual missions and mystiques on others, thereby fulfilling--and, sometimes, creating--distinct needs in their followers. The volume brings into vivid focus issues with the potential for devastating consequences on the global stage. This must-have Second Edition is indispensable reading for researchers, professors, and graduate students across many disciplines, including political psychology, psychoanalysis, history and political science, psychiatry, anthropology, and personality and social psychology. It is important reading for anyone with an interest in the life stories of leaders past and present and how they affect our world even long after they are gone.
- Contents
- Part I. The Past -- Leaders in Ancient Times: Joseph, Plato, Alcibiades -- Freud and His Followers -- From Erik E. Erikson to Heinz Kohut: Expanding Theories of Leadership -- Part II. Studies -- Lincoln and the Crisis of the 1850s: Thoughts on the Group Self -- Mirror Image of the Nation: An Investigation of Kaiser Wilhelm II's Leadership of Germans -- Osama Bin Laden: The Man and the Myth -- Redemptive Narratives in the Life and the Presidency of George W. Bush -- Paranoid Leadership.
- Format
- e-Book
- Location
- Online
Partnerships for Mental Health : Narratives of Community and Academic Collaboration
https://libcat.nshealth.ca/en/permalink/provcat39327
Laura Weiss Roberts, Daryn Reicherter, Steven Adelsheim, Shashank V. Joshi, editors.
--Cham:
Springer
, c2015.
- Available Online
- View e-Book
- Location
- Online
This unique title richly tells the stories of partnership and collaboration. The narrative voice of each chapter derives from the people who tell their story -- immigrants, survivors of torture, mental health experts, urban people, rural people, teachers, doctors, attorneys, students, and international leaders. These authors provide emotionally powerful tales that move, affect, and encourage readers. The collection of narratives is inspired by these individuals, who believe that collaboration c…
- Available Online
- View e-Book
- Responsibility
- Laura Weiss Roberts, Daryn Reicherter, Steven Adelsheim, Shashank V. Joshi, editors
- Place of Publication
- Cham
- Publisher
- Springer
- Date of Publication
- c2015
- Physical Description
- 1 online resource (xxviii, 210 p. : 6 illus., 5 illus. in color)
- ISBN
- 9783319188843
- 9783319188836 (print ed.)
- Subjects (MeSH)
- Academic Medical Centers
- Community Health Planning
- Community Mental Health Services
- Models, Organizational
- Abstract
- This unique title richly tells the stories of partnership and collaboration. The narrative voice of each chapter derives from the people who tell their story -- immigrants, survivors of torture, mental health experts, urban people, rural people, teachers, doctors, attorneys, students, and international leaders. These authors provide emotionally powerful tales that move, affect, and encourage readers. The collection of narratives is inspired by these individuals, who believe that collaboration can bring authentic mutualism, promise-keeping, and innovation to address the hardest problems we face as a world community. Partnerships for Mental Health: Narratives of Community and Academic Collaboration is about the stories of innovation and collaboration occurring between community and academic partners who have undertaken among the very hardest of problems, such as the care of veterans with ravaging posttraumatic stress disorder; the care of homeless individuals with HIV, addiction, and mental illness; the care of caregivers for Hispanic family members with Alzheimer's disease; the prevention of illness in impoverished vulnerable youth; and the rescue of profoundly mentally ill earthquake survivors. In addition, this title not only also tells the story of identity formation of early-career physicians with a calling to work with distinct populations for whom suffering and stigma are immense, but also the stories of the special bonds that develop and are strengthened between community members and academic colleagues and, ultimately, between friends. A truly indispensable contribution to the literature, this captivating and novel title illustrates and inspires collaboration in order to bring about better health outcomes for people affected by mental health issues in communities throughout the world.
- Contents
- Acknowledgements -- Dedications -- Foreword. Partnerships Between Academic Medical Centers and Community-Based Organizations Enhance the Mission and Impact of Each -- Preface -- Introduction. Beginning with a Single Step -- Narrative 1. The Stanford-Santa Clara County Methamphetamine Task Force -- Narrative 2. Building Relationships with At-Risk Populations: A Community Engagement Approach for Longitudinal Research -- Narrative 3. The Center for Youth Wellness: A Community-based Approach to Holistic Health Care in San Francisco -- Narrative 4. The Cambodian Lotus Thrives under a California Sun: How a Mental Health Clinic Partnered with a Khmer Buddhist Temple to Reach Killing Fields Refugees Living in California -- Narrative 5. Kombis, Brothels and Violence Against Women: Building Global Health Partnerships to Address Women's Health and Empowerment -- Narrative 6. Creating a National Native Telebehavioral Health Network: The IHS Telebehavioral Health Center of Excellence -- Narrative 7. The Program of Assertive Community Treatment and the University of Wisconsin Psychiatry Residency -- Narrative 8. Laughing at the Rain -- Narrative 9. From the Ivory Tower to the Real World: Translating an Evidence-Based Intervention for Latino Dementia Family Caregivers into a Community Setting -- Narrative 10. Implementing a Peer Support Program for Veterans: Seeking new models for the provision of community based outpatient services for Posttraumatic Stress Disorder and Substance Use Disorders -- Narrative 11. A Journey of Mutual Growth: Mental Health Awareness in the Muslim Community -- Narrative 12. The Intercultural Psychiatric Program at Oregon Health and Science University -- Narrative 13. Shared Learning in Community-Academic Partnerships: Addressing the Needs of Schools -- Narrative 14. The Earthquake -- Narrative 15. Voices of Experience: Questions and Answers.
- Format
- e-Book
- Location
- Online
