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From Thoracic Surgery to Interventional Pulmonology

https://libcat.nshealth.ca/en/permalink/provcat47097
J. Francis Turner, Jr., Prasoon Jain, Kazuhiro Yasufuku, Atul C. Mehta. Humana , 2021.
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Location
Online
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Responsibility
J. Francis Turner, Jr., Prasoon Jain, Kazuhiro Yasufuku, Atul C. Mehta
Publisher
Humana
Date of Publication
2021
Physical Description
1 online resource (xiv, 306 pages) : illustrations
Series Title
Respiratory medicine
ISBN
9783030802981
Specialty
Respiratory System
Thoracic Surgery
Radiology, Interventional
Format
e-Book
Location
Online
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Moyamoya Disease Explored Through RNF213 : Genetics, Molecular Pathology, and Clinical Sciences

https://libcat.nshealth.ca/en/permalink/provcat41964
Akio Koizumi, Kazuhiro Nagata, Kiyohiro Houkin, Teiji Tominaga, Susumu Miyamoto, Shigeo Kure, Elizabeth Tournier-Lasserve, editors. --Singapore: Springer , 2017.
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Online
This book presents the latest findings on biological, epidemiological, and clinical investigations of RNF213, which is thought to be involved in many biological processes and plays a key role in cerebro- and cardiovascular disease . By discussing the epidemiology and genetic epidemiology of the disease with a particular focus on the molecular function of RNF213, research using animal models, diagnosis, therapy and clinical management around the world, this work makes a valuable contribution to …
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Other Authors
Koizumi, Akio
Nagata, Kazuhiro
Houkin, Kiyohiro
Tominaga, Teiji
Miyamoto, Susumu
Kure, Shigeo
Tournier-Lasserve, Elizabeth
Responsibility
Akio Koizumi, Kazuhiro Nagata, Kiyohiro Houkin, Teiji Tominaga, Susumu Miyamoto, Shigeo Kure, Elizabeth Tournier-Lasserve, editors
Place of Publication
Singapore
Publisher
Springer
Date of Publication
2017
Physical Description
1 online resource (viii, 185 pages) : 36 illus., 22 illus. in color
Series Title
Current Topics in Environmental Health and Preventive Medicine
ISBN
9789811027116
9789811027109 (print ed.)
ISSN
2364-8333
Subjects (MeSH)
Adenosine Triphosphatases - genetics
Genetic Predisposition to Disease
Moyamoya Disease - genetics
Moyamoya Disease - physiopathology
Ubiquitin-Protein Ligases - genetics
Abstract
This book presents the latest findings on biological, epidemiological, and clinical investigations of RNF213, which is thought to be involved in many biological processes and plays a key role in cerebro- and cardiovascular disease . By discussing the epidemiology and genetic epidemiology of the disease with a particular focus on the molecular function of RNF213, research using animal models, diagnosis, therapy and clinical management around the world, this work makes a valuable contribution to the study of the disease. Moyamoya Disease Explored Through RNF213 is an indispensable resource for both beginning and experienced researchers, pediatricians, neurologists, and neurosurgeons who are seeking comprehensive information on adult and childhood stroke.
Contents
Part I: Prologue -- 1. A prologue to moyamoya disease and RNF213 -- 2. Concept of moyamoya Disease -- Part II: Genetic Epidemiology -- 3. Molecular Epidemiology in East Asian Countries and in the World -- Part III: Biochemistry, Function and Molecular Pathology -- 4. Molecular Biology of Mysterin/RNF213 -- 5. Physiological Role of Mysterin/RNF213 in Zebrafish -- 6. Pathological Investigation on RNF213: Animal Models Knockout and Transgenic Mice in Diabetes and Signal Transduction -- 7. Pathological Investigation on RNF213: Animal Models of Rnf213-knockout and Knock-in Mice -- 8. RNF213 and Circulating Factors in Patients with Moyamoya Disease -- 9. Genetics of Moyamoya beyond RNF213. Monogenic Moyamoya Syndromes -- Part IV: Clinical Management 10. Natural History and Long-term Clinical Outcome after Conservative and Surgical Management -- 11. Significance of RNF213 in Clinical Management in Japan -- 12. Significance of RNF213 in Clinical Management in China -- 13. The Different Forms of Moyamoya Disease and Their Clinical Management -- 14. Vascular Diseases Attributable to RNF213 Other than Moyamoya Disease -- Part V: Epilogue -- 15. Future Clinical Perspectives on RNF213 in Moyamoya Disease.
Format
e-Book
Location
Online
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Structure-Function Relationships in Various Respiratory Systems : Connecting to the Next Generation

https://libcat.nshealth.ca/en/permalink/provcat45213
Kazuhiro Yamaguchi, editor. --Singapore: Springer , c2020.
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This book elucidates the morphological backgrounds of various functional parameters of the human respiratory system, including the respiratory control system, dynamics of the upper and lower airways, gas transport and mixing in the lower airways, gas exchange in the acinus, and gas transfer through the alveolar wall. Presenting the latest findings on the interrelationships between morphology and physiology in the respiratory system, the book’s goal is to provide a foundation for further explori…
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Other Authors
Yamaguchi, Kazuhiro
Responsibility
Kazuhiro Yamaguchi, editor
Place of Publication
Singapore
Publisher
Springer
Date of Publication
c2020
Physical Description
1 online resource (viii, 294 p.) : 95 illus., 59 illus. in color
Series
Respiratory Disease Series: Diagnostic Tools and Disease Managements
Series Title
Respiratory disease series
ISBN
9789811555961
9789811555954 (Print ed.)
9789811555978 (Print ed.)
9789811555985 (Print ed.)
ISSN
2509-5552
Subjects (MeSH)
Respiratory Physiological Phenomena
Specialty
Physiology
Pulmonary Medicine
Abstract
This book elucidates the morphological backgrounds of various functional parameters of the human respiratory system, including the respiratory control system, dynamics of the upper and lower airways, gas transport and mixing in the lower airways, gas exchange in the acinus, and gas transfer through the alveolar wall. Presenting the latest findings on the interrelationships between morphology and physiology in the respiratory system, the book’s goal is to provide a foundation for further exploring structure-function relationships in various respiratory systems, and to improve both the quality of basic science, and that of clinical medicine targeting the human respiratory system. Edited and written by internationally recognized experts, Structure-Function Relationships in Various Respiratory Systems offers a valuable asset for all physicians and researchers engaging in clinical, physiological, or morphological work in the field of respiration. Moreover, it provides a practical guide for physicians, helping them make more precise pathophysiological decisions concerning patients with various types of lung disease, and will be of interest to respiratory physiologists and respiratory morphologists.
Contents
Part I. Respiratory Control System -- 1. Anatomy and Physiology of Respiratory Control System: How Are Respiratory Controlling Cells Communicating in the Brain? -- 2. Anatomy and Physiology of Chemical Regulatory Mechanisms in Respiration: How Does Chemical Regulation Work with Various Acid–Base Disorders? -- 3. Coordination of Swallowing and Breathing: How Is the Respiratory Control System Connected to the Swallowing System? -- Part II. Upper Airway -- 4. Anatomy and Function of Upper Airway During Sleep: What Are Essential Mechanisms Eliciting Apneas During Sleep? -- 5. Instability of Upper Airway During Anesthesia and Sedation: How Is Upper Airway Unstable During Anesthesia and Sedation? -- Part III. Lower Airway -- 6. Convective and Diffusive Mixing in Lower and Acinar Airways: Is Diffusive Mixing Effective in the Lung Periphery? -- 7. Radiological Evaluation of Lower Airway Dimensions Deciding Ventilatory Dynamics: Can Radiologically Determined, Static Airway Structures Precisely Predict Ventilatory Dysfunction? -- 8. Functional Properties of Lower Airway Estimated by Oscillometry: Is Oscillometry Useful for Detecting Lower-Airway Abnormalities? -- Part IV. Acinus -- 9. Inhomogeneous Distribution of Ventilation–Perfusion (VA/Q) and Diffusing Capacity–Perfusion (D/Q) in the Lung: What Abnormal VA/Q and D/Q Distributions Are Detected in Diseased Lungs? -- 10. Physiological Basis of Effective Alveolar–Arterial O2 Difference (AaDO2) and Effective Physiological Dead Space (VD/VT): Are AaDO2 and VD/VT Supported by Structurally and Physiologically Correct Knowledges? -- 11. Oxygen Transport from Air to Tissues as an Integrated System: What Limits Maximal O2 Consumption in Health and Disease? -- Part V. Alveolar Wall -- 12. Pathophysiological and Clinical Implication of Diffusing Capacity for CO (DLco) and Krogh Factor (Kco): How Do DLCO and KCO Differentiate Various Lung Diseases? -- 13. Basic Perspective of Simultaneous Measurement of DLCO and DLNO: What Are the Most Legitimate Assumptions When Estimating DLCO and DLNO? -- 14. Reference Equations for Simultaneously Measured DLCO and DLNO: How Are Reference Equations Influenced by Age, Sex, and Anthropometric Variables? -- 15. Differential Diagnosis Based on the Newly Developed Indicator of DLNO/DLCO: What Are Pathophysiological Backgrounds on DLNO/DLCO? -- 16. Clinical Significance of Simultaneous Measurements of DLCO and DLNO: Can DLCO and DLNO Differentiate Various Kinds of Lung Diseases?
Format
e-Book
Location
Online
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