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60 years of survival outcomes at the University of Texas MD Anderson Cancer Center

https://libcat.nshealth.ca/en/permalink/provcat32423
M. Alma Rodriguez, Ronald S. Walters, Thomas W. Burke, editors. --New York, NY: Springer , c2013.
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This unique book provides a retrospective analysis of the changes in survival outcomes at The University of Texas M.D. Anderson Cancer Center over the past six decades. Since opening its doors in 1944, M.D. Anderson has kept a continuous, uninterrupted data repository of the treatment and outcomes of each of its patients. It is this visionary database from the Center's tumor registry which makes this groundbreaking book possible. Tracking results across time, the book shows radical shifts in ou…
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Rodriguez, M. Alma
Walters, Ronald S
Burke, Thomas W
Responsibility
M. Alma Rodriguez, Ronald S. Walters, Thomas W. Burke, editors
Place of Publication
New York, NY
Publisher
Springer
Date of Publication
c2013
Physical Description
1 online resource (xiii, 346 p. : 124 ill. in color)
ISBN
9781461451976
Subjects (MeSH)
Academies and Institutes - history
History, 20th century
History, 21st century
Neoplasms - epidemiology
Neoplasms - therapy
Registries
Survival Analysis
Texas - epidemiology
Treatment Outcome
Subjects (LCSH)
Oncology
Epidemiology
Abstract
This unique book provides a retrospective analysis of the changes in survival outcomes at The University of Texas M.D. Anderson Cancer Center over the past six decades. Since opening its doors in 1944, M.D. Anderson has kept a continuous, uninterrupted data repository of the treatment and outcomes of each of its patients. It is this visionary database from the Center's tumor registry which makes this groundbreaking book possible. Tracking results across time, the book shows radical shifts in outcomes trends, where great progress has been made, and where there is still a long way to go, and offers a snapshot of the parallel history of developments in care. Such data is crucial to informing how patients are counseled, how treatment decisions are determined, and how prognoses are made. 60 Years of Survival Outcomes at The University of Texas M.D. Anderson Cancer Center is the only book to concurrently present longitudinal data on survival outcomes across the spectrum of rare and common cancers. Each chapter deals with a specific disease site, discussing current management approaches and presenting key data replete with illustrative charts, graphs, and tables. With the resources available only to the practitioners at this inimitable institution, this book heralds a cornerstone moment in the study of survival outcomes and the depth of our knowledge of cancer care.
Contents
Ch. 1:Introduction -- Ch. 2:History of MD Anderson's Tumor Registry -- Ch. 3:Statistical Methods -- Ch. 4:Breast Cancer -- Ch. 5:Prostate Cancer -- Ch. 6:Non-Small Cell Lung Cancer -- Ch. 7:Small Cell Lung Cancer -- Ch. 8:Colon Cancer -- Ch. 9:Ovarian Cancer -- Ch. 10:Cervical Cancer -- Ch. 11:Endometrial Cancer -- Ch. 12:Pancreatic Cancer (Exocrine) -- Ch. 13:Kidney Cancer -- Ch. 14:Bladder Cancer -- Ch. 15:Cutaneous Melanoma -- Ch. 16:Liver Cancer -- Ch. 17:Esophageal Cancer -- Ch. 18:Gastric Cancer -- Ch. 19:Acute Myeloid Leukemia -- Ch. 20:Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma -- Ch. 21:Hodgkin Lymphoma -- Ch. 22:Non-Hodgkin Indolent B-Cell Lymphoma -- Ch. 23:Non-Hodgkin Aggressive B-Cell Lymphoma -- Ch. 24:Multiple Myeloma -- Ch. 25:Head and Neck Cancer -- Ch. 26:Thyroid Cancer -- Ch. 27:Soft Tissue Sarcomas -- Ch. 28:Sarcomas of Bone -- Index.
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e-Book
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Abdomen and thoracic imaging : an engineering & clinical perspective

https://libcat.nshealth.ca/en/permalink/provcat33315
Ayman S. El-Baz, Luca Saba, Jasjit Suri, editors. --New York: Springer , c2014.
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This book will cover all the imaging techniques, potential for applying such imaging clinically, and offer present and future applications as applied to the abdomen and thoracic imaging with the most world renowned scientists in these fields. The main aim of this book is to help advance scientific research within the broad field of abdominal imaging. This book focuses on major trends and challenges in this area, and it presents work aimed to identify new techniques and their use in medical imag…
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El-Baz, Ayman S
Saba, Luca
Suri, Jasjit S
Responsibility
Ayman S. El-Baz, Luca Saba, Jasjit Suri, editors
Place of Publication
New York
Publisher
Springer
Date of Publication
c2014
Physical Description
1 online resource (ix, 773 pages)
ISBN
9781461484981 (electronic bk.)
9781461484974
Subjects (MeSH)
Abdomen - pathology
Thorax - pathology
Subjects (LCSH)
Abdomen - Imaging
Chest - Imaging
Diagnostic imaging
Abstract
This book will cover all the imaging techniques, potential for applying such imaging clinically, and offer present and future applications as applied to the abdomen and thoracic imaging with the most world renowned scientists in these fields. The main aim of this book is to help advance scientific research within the broad field of abdominal imaging. This book focuses on major trends and challenges in this area, and it presents work aimed to identify new techniques and their use in medical imaging analysis for abdominal imaging.
Contents
1. Computer-Aided Diagnosis Systems for Acute Renal Transplant Rejection: Challenges and Methodologies -- 2. Kidney Detection and Segmentation in Contrast-Enhanced Ultrasound 3D Images -- 3. Renal Cortex Segmentation on Computed Tomography -- 4. Diffuse Fatty Liver Disease: From Diagnosis to Quantification -- 5. Multimodality Approach to Detection and Characterization of Hepatic Hemangiomas -- 6. Ultrasound Liver Surface and Textural Characterization for the Detection of Liver Cirrhosis -- 7. MR Imaging of Hepatocellular Carcinoma -- 8. Magnetic Resonance Imaging of Adenocarcinoma of the Pancreas -- 9. Quantitative Evaluation of Liver Function Within MR Imaging -- 10. Diffusion-Weighted Imaging of the Liver -- 11. Shape-Based Liver Segmentation Without Prior Statistical Models -- 12. CT Imaging Characteristics of Hepatocellular Carcinoma -- 13. Clinical Applications of Hepatobiliary MR Contrast Agents -- 14. Fast Object Detection Using Color Features for Colonoscopy Quality Measurements -- 15. Colon Surface Registration Using Ricci Flow -- 16. Efficient Topological Cleaning for Visual Colon Surface Flattening -- 17. Towards Self-Parameterized Active Contours for Medical Image Segmentation with Emphasis on Abdomen -- 18. Bridging the Gap Between Modeling of Tumor Growth and Clinical Imaging -- 19. Evaluation of Medical Image Registration by Using High-Accuracy Image Matching Techniques -- 20. Preclinical Visualization of Hypoxia, Proliferation and Glucose Metabolism in Non-small Cell Lung Cancer and Its Metastasis -- 21. Thermoacoustic Imaging with VHF Signal Generation: A New Contrast Mechanism for Cancer Imaging Over Large Fields of View -- 22. Automated Prostate Cancer Localization with Multiparametric Magnetic Resonance Imaging -- 23. Ultrasound-Fluoroscopy Registration for Intraoperative Dynamic Dosimetry in Prostate Brachytherapy -- 24. Multi-Atlas-Based Segmentation of Pelvic Structures from CT Scans for Planning in Prostate Cancer Radiotherapy -- 25. Propagating Segmentation of a Single Example to Similar Images: Differential Segmentation of the Prostate in 3-D MRI -- 26. 3D Registration of Whole-Mount Prostate Histology Images to Ex Vivo Magnetic Resonance Images Using Strand-Shaped Fiducials -- 27. Anatomical Landmark Detection.
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e-Book
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Abdominal Imaging

https://libcat.nshealth.ca/en/permalink/provcat40778
Bernd Hamm, Pablo R. Ros, editors. --Berlin, Heidelberg: Springer Reference , c2013.
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In this book a team of leading experts come together to provide a comprehensive overview of modern imaging of the abdomen and pelvis, with detailed sections on both gastrointestinal and genitourinary imaging. Each chapter has an identical structure and focuses on a particular organ or organ system, allowing the reader to approach the field one topic at a time. Indications for a variety of imaging techniques and examination protocols are clearly described, and the imaging features of normal anat…
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Hamm, Bernd
Ros, Pablo R
Responsibility
Bernd Hamm, Pablo R. Ros, editors
Place of Publication
Berlin, Heidelberg
Publisher
Springer Reference
Date of Publication
c2013
Physical Description
1 online resource (lii, 2316 p.) : 2233 illus., 540 illus. in color
ISBN
9783642133275
9783642133268 (print ed.)
Subjects (MeSH)
Abdomen - diagnostic imaging
Pelvis - diagnostic imaging
Radiography, Abdominal
Abstract
In this book a team of leading experts come together to provide a comprehensive overview of modern imaging of the abdomen and pelvis, with detailed sections on both gastrointestinal and genitourinary imaging. Each chapter has an identical structure and focuses on a particular organ or organ system, allowing the reader to approach the field one topic at a time. Indications for a variety of imaging techniques and examination protocols are clearly described, and the imaging features of normal anatomy and pathologic entities are depicted in an abundance of high-quality images. Care is taken to consider all recent technical developments and new indications, and the diagnostic performance of different imaging modalities is carefully compared. It is anticipated that this book will come to be regarded as the standard work of reference on abdominal and pelvic radiology.
Contents
Vol. 1. I. Pharynx and esophagus -- II. Stomach, Duodenum -- III. Small Bowel Excluding Duodenum -- Vol. 2. IV. Colon and rectum -- V. Liver -- VI. Biliary Diseases -- Vol. 3. VII. Pancreas -- VIII. Spleen -- IX. Mesentery, Omentum, Peritoneum, Abdominal Wall -- X. Retroperitoneum -- XI. Kidney and renal pelvis -- XII. Prostate -- Vol. 4. XIII. Scrotum and penis -- XIV. Ureter and urethra -- XV. Ovary and adnexa -- XVI. Uterus -- XVII. Vagina and vulva -- XVIII. Pregnancy.
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e-Book
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Abdominal Solid Organ Transplantation : Immunology, Indications, Techniques, and Early Complications

https://libcat.nshealth.ca/en/permalink/provcat39265
Antonio Daniele Pinna, Giorgio Ercolani, editors. (1st ed.) --Cham: Springer , c2015.
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This book is a comprehensive and innovative guide to abdominal solid organ transplantation (SOT). It explains the main immunological problems involved in abdominal SOT, reviews indications for liver, kidney, and small bowel transplantation, and provides detailed descriptions of techniques for procurement and transplantation. In addition, technical, infectious, and immunological complications and their treatment are fully described. Special attention is devoted to the indications for and outcome…
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Other Authors
Pinna, Antonio Daniele
Ercolani, Giorgio
Responsibility
Antonio Daniele Pinna, Giorgio Ercolani, editors
Edition
1st ed.
Place of Publication
Cham
Publisher
Springer
Date of Publication
c2015
Physical Description
1 online resource (ix, 453 p. : 94 illus., 85 illus. in color)
ISBN
9783319169972
9783319169965 (print ed.)
Subjects (MeSH)
Organ Transplantation
Surgical Procedures, Operative
Abstract
This book is a comprehensive and innovative guide to abdominal solid organ transplantation (SOT). It explains the main immunological problems involved in abdominal SOT, reviews indications for liver, kidney, and small bowel transplantation, and provides detailed descriptions of techniques for procurement and transplantation. In addition, technical, infectious, and immunological complications and their treatment are fully described. Special attention is devoted to the indications for and outcomes of combined kidney-liver and kidney-pancreas transplantation. Clear advice is provided on donor selection and donor safety, and the book concludes by examining medical disease and the risk of solid and hematologic malignancies after transplantation. Abdominal SOT has become the treatment of choice for various end-stage chronic diseases of the liver, kidney, and foregut. Improved knowledge of immunology, the introduction of new immunosuppressive agents, and advances in surgical techniques have all increased the number of potential candidates and led to better outcomes. It is therefore unsurprising that more and more surgeons, physicians, and scientists, as well as students and nurses, are becoming interested in abdominal SOT. This book will provide all practitioners with an excellent, up-to-date summary of knowledge in the field.
Contents
Part I Donor evaluation, immunosuppression and early complications in S.O.T.: 1 Immunosuppression in solid organ transplantation -- 2 Infection Complications after Abdominal Organ Transplantation -- 3 National Transplant Network. Donor selection and evaluation criteria -- 4 The safety of donor -- 5 Medical disease after abdominal solid organ transplantation and the risk of solid and hematologic malignant tumor after transplantation) -- Part II Liver Transplantation: 6 Indication and timing -- 7 The donor procurement -- 8 Orthotopic liver transplantation -- 9 Anesthetic and perioperative management for liver transplantation -- 10 Living donor liver transplantation -- 11 Hepatic Acute and chronic rejection -- 12 Postoperative technical complications -- 13 Percutaneous management of biliary and vascular complications -- 14 Re-transplantation (Causes, Outcome) -- Part III Renal transplantation: 15 Indication and timing -- 16 The donor procurement: Standard technique for procurement in cadaveric donors -- 17 Live donor evaluation -- 18 Living donor nephrectomy -- 19 Renal Transplantation: Surgical technique -- 20 The intraoperative and perioperative management of Kidney transplantation -- 21 Kidney acute and chronic rejection -- 22 Kidney Transplantation: Post-Operative Technical Complications -- Part V Intestinal/multivisceral transplantation: 23 Indications and timing -- 24 The donor procurement -- 25 Transplantation -- 26 Abdominal wall transplantation and technique -- 27 Anesthetic and perioperative management for Intestinal transplantation -- 28 Segmental Living-related Small Bowel Transplantation -- 29 Intestinal Acute and Chronic rejection -- Part VI Combined Abdominal Transplantation: 30 Combined Kidney-Liver Transplantation -- 31 Kidney-pancreas Transplantation.
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e-Book
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ABO-incompatible Organ Transplantation

https://libcat.nshealth.ca/en/permalink/provcat44154
edited by Yi Wang. --Singapore: Springer , 2019.
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This book introduces the clinical application of ABO-incompatible transplantation. In the first part, it starts with the history, blood group antigen, antibody associated with ABO blood type, pathophysiology and pathology and related knowledge. In the second part, it covers clinical experience sharing of ABO-incompatible of heart, liver, lung and kidney transplantation. It provides a systematic methodologies and protocols.
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Wang, Yi.
Responsibility
edited by Yi Wang.
Place of Publication
Singapore
Publisher
Springer
Date of Publication
2019
Physical Description
1 online resource (xxiii, 274 p. 12 illus., 5 illus. in color)
ISBN
9789811333996
9789811333989 (Print ed.)
9789811334009 (Print ed.)
Subjects (MeSH)
ABO Blood-Group System - immunology
Antibodies - blood
Blood Group Incompatibility
Organ Transplantation - methods
Transplants - immunology
Specialty
Transplantation
Abstract
This book introduces the clinical application of ABO-incompatible transplantation. In the first part, it starts with the history, blood group antigen, antibody associated with ABO blood type, pathophysiology and pathology and related knowledge. In the second part, it covers clinical experience sharing of ABO-incompatible of heart, liver, lung and kidney transplantation. It provides a systematic methodologies and protocols.
Contents
1. Introduction -- 2. The RBC blood group antigen system -- 3. ABO blood group antibodies -- 4. Tissue matching of ABO-incompatible organ transplantation -- 5. Indications for ABO-incompatible organ transplantation -- 6. Pathophysiology of ABO-incompatible organ transplantation -- 7. Pathology of ABO-incompatible organ transplantation -- 8. Anti-ABO antibody elimination: pre- and post-ABO-incompatible kidney transplantation -- 9. Rejection after ABO-incompatible organ transplantation -- 10. Experience with ABO-incompatible heart transplantation -- 11. Experience with ABO-incompatible liver transplantation -- 12. Experience with ABO-incompatible kidney transplantation -- 13. Experience with ABO-incompatible lung transplantation -- 14. The animal model in ABO-incompatible organ transplantation -- 15. Mechanism development of accommodation and tolerance in transplant -- Appendix: The Clinical Guideline of ABO-Incompatible Kidney Transplantation (2017) / Chinese Society of Organ Transplantation.
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e-Book
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Absolute Nephrology Review : An Essential Q & A Study Guide

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Alluru S. Reddi. (1st ed.) --Cham: Springer , c2016.
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Written in a succinct question and answer format, this comprehensive resource covers all areas of nephrology and common clinical scenarios. Nearly 1000 questions with detailed answers provide nephrology fellows, practicing nephrologists and clinicians a better understanding of nephrology and aid preparations for nephrology and internal medicine boards. Absolute Nephrology Review features the latest evidence and guidelines while fulfilling a critical need within the nephrology community.
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Author
Reddi, Alluru S
Responsibility
Alluru S. Reddi
Edition
1st ed.
Place of Publication
Cham
Publisher
Springer
Date of Publication
c2016
Physical Description
1 online resource (vii, 490 p. : 73 illus., 19 illus. in color)
ISBN
9783319229485
9783319229478 (print ed.)
Subjects (MeSH)
Kidney Diseases
Abstract
Written in a succinct question and answer format, this comprehensive resource covers all areas of nephrology and common clinical scenarios. Nearly 1000 questions with detailed answers provide nephrology fellows, practicing nephrologists and clinicians a better understanding of nephrology and aid preparations for nephrology and internal medicine boards. Absolute Nephrology Review features the latest evidence and guidelines while fulfilling a critical need within the nephrology community.
Contents
1. Fluids, Electrolytes, and Acid-Base Disorders -- 2. Disorders of Mineral Metabolism and Nephrolithiasis -- 3. Acute Kidney Injury -- 4. Chronic Kidney Disease -- 5. Glomerular, Tubulointerstitial, and Vascular Diseases -- 6. Genetic Diseases and Pregnancy -- 7. Hypertension -- 8. Renal Pharmacology -- 9. Hemodialysis -- 10. Peritoneal Dialysis -- 11. Transplantation.
Format
e-Book
Publication Type
Examination Questions
Problems and Exercises
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Online
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ACEi and ARBS in Hypertension and Heart Failure

https://libcat.nshealth.ca/en/permalink/provcat39106
Pasquale Perrone Filardi, editor. --Cham: Springer International Publishing : Imprint: Springer ; ISCP , c2015.
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This book summarizes how the renin angiotensin system is implicated in the progression of atherosclerotic disease as well as of left ventricular dysfunction and reviews the action of angiotensin converting enzyme inhibitors and AT1 receptor antagonists on reducing morbidity and mortality in patients with left ventricular dysfunction or in those at high cardiovascular risk with preserved ventricular function. ACEi and ARBS in Hypertension and Heart Failure is a highly practical reference reviewi…
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Other Authors
Perrone Filardi, Pasquale
Other Authors
International Society of Cardiovascular Pharmacotherapy
Responsibility
Pasquale Perrone Filardi, editor
Alternate Title
Angiotensin converting enzyme inhibitors and angiotensin II receptor blockers in hypertension and heart failure
Place of Publication
Cham
Publisher
Springer International Publishing : Imprint: Springer ; ISCP
Date of Publication
c2015
Physical Description
1 online resource (x, 150 p. : 19 illus., 13 illus. in color)
Series Title
Current cardiovascular therapy
ISBN
9783319097886
9783319097879 (print ed.)
Subjects (MeSH)
Angiotensin II Type 1 Receptor Blockers
Angiotensin-Converting Enzyme Inhibitors - pharmacology
Heart Failure - drug therapy
Hypertension - drug therapy
Renin-Angiotensin System
Abstract
This book summarizes how the renin angiotensin system is implicated in the progression of atherosclerotic disease as well as of left ventricular dysfunction and reviews the action of angiotensin converting enzyme inhibitors and AT1 receptor antagonists on reducing morbidity and mortality in patients with left ventricular dysfunction or in those at high cardiovascular risk with preserved ventricular function. ACEi and ARBS in Hypertension and Heart Failure is a highly practical reference reviewing the evidence and providing a rationale for the appropriate use of RAS antagonists in cardiovascular diseases. It is written in an easy-to-follow format and with many illustrations to aid clarity and the assimilation of information. Each chapter is written by established authorities in their fields who are also experienced in explaining often complex concepts. The result is a unique book which is not only comprehensive but also clear and useful for the busy medical practitioner.
Contents
1. Angiotensin Converting Enzyme Inhibitors and AT1 Antagonists for Treatment of Hypertension -- 2. ACE Inhibitor and Renin–Angiotensin System the Cornerstone of Therapy for Systolic Heart Failure -- 3. Impact of Chronic Kidney Disease and Diabetes Mellitus on Choice of Renin Angiotensin System: Inhibitors in Patients with Hypertension and Heart Failure -- 4. Target Organ Damage and RAAS Blockade.
Format
e-Book
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Online
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Acupuncture for Pain Management

https://libcat.nshealth.ca/en/permalink/provcat39577
Yuan-Chi Lin, Eric Shen-Zen Hsu, editors. --New York, NY: Springer , c2014.
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Acupuncture for Pain Management is intended as the premier resource for learning the fundamentals of the art of medical acupuncture. Edited by top pain medicine specialists at Harvard and UCLA, and based on their popular annual workshop at the American Society for Anesthesiologists, the book is the perfect synthesis of Western and Chinese medicine. Anesthesiologists, pain medicine specialists, primary care physicians, osteopaths, neurologists, psychiatrists, physical medicine and rehabilitation…
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Other Authors
Lin, Yuan-Chi
Hsu, Eric Shen-Zen
Responsibility
Yuan-Chi Lin, Eric Shen-Zen Hsu, editors
Place of Publication
New York, NY
Publisher
Springer
Date of Publication
c2014
Physical Description
1 online resource (xiv, 276 p. : 54 illus., 49 illus. in color)
ISBN
9781461452751
9781461452744 (print ed.)
Subjects (MeSH)
Acupuncture Therapy
Pain Management
Abstract
Acupuncture for Pain Management is intended as the premier resource for learning the fundamentals of the art of medical acupuncture. Edited by top pain medicine specialists at Harvard and UCLA, and based on their popular annual workshop at the American Society for Anesthesiologists, the book is the perfect synthesis of Western and Chinese medicine. Anesthesiologists, pain medicine specialists, primary care physicians, osteopaths, neurologists, psychiatrists, physical medicine and rehabilitation specialists, and other health professionals looking to add acupuncture to their repertoire will benefit from the concise and practical approach of the book. Features: Each individual meridian discussed in detail Acupuncture for 25 clinical conditions, including headache, menstrual pain, low back pain, insomnia, and more. Aimed at acupuncturists as well as practitioners who want to add acupuncture to their clinical armamentarium.
Contents
Part I: General Consideration -- 1. History of Acupuncture -- 2. Basic Theories of Traditional Chinese Medicine -- 3. Pattern Discrimination in Traditional Chinese Medicine (TCM) -- 4. Mechanisms of Acupuncture Analgesia -- 5. Common Acupuncture Practices -- 6. Peri-Operative Acupuncture -- 7. Acupuncture Pain Research: Quantitative and Qualitative -- 8. Auricular Acupuncture -- Part II: Acupuncture Channels -- 9. Acupuncture Qi Flow and Points Measurement -- 10. Hand Tai Yin Lung Meridian -- 11. Hand Yang Ming Large Intestine Meridian -- 12. Foot Yang Ming Stomach Meridian -- 13. Foot Tai Yin Spleen Meridian -- 14. The Hand Sho Yin Heart Meridian -- 15. The Hand Tai Yang Small Intestine Meridian -- 16. Foot Tai Yang Bladder Meridian -- 17. Foot Shao Yin Kidney Meridian -- 18. The Hand Jue Yin Pericardium Meridian -- 19. The Hand Sho Yang Triple Energizer Meridian -- 20. The Foot Shao Yang Gall Bladder Meridian -- 21. The Foot Jun Yin Liver Meridian -- 22. Conception Vessel -- 23. Governor Vessel -- 24. The Extra Acupuncture Points -- Part III: Clinical Conditions -- 25. Headache -- 26. Facial nerve palsy -- 27. Vertigo -- 28. Toothache -- 29. Neck Pain -- 30. Chest Pain -- 31. Epigastic Pain -- 32. Abdominal Pain -- 33. Dysmenorrhea -- 34. Upper Back Pain -- 35. Frozen Shoulder -- 36. Low Back Pain -- 37. Arthritis, Joint Pain -- 38. Coccygeal Pain -- 39. Elbow Pain -- 40. Wrist Pain -- 41. Ankle Pain -- 42. Heel Pain -- 43. Insomnia -- 44. Nausea and Vomiting -- 45. Sedation -- 46. Dizziness.
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e-Book
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Online
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Acute Nephrology for the Critical Care Physician

https://libcat.nshealth.ca/en/permalink/provcat39281
Heleen M. Oudemans-van Straaten, Lui G. Forni, A.B. Johan Groeneveld, Sean M. Bagshaw, Michael Joannidis, editors. --Cham: Springer , c2015.
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This practical guide provides the reader with answers to important clinically relevant questions regarding the evaluation and management of acute kidney injury (AKI). All aspects of critical care nephrology are covered, from pathophysiology and diagnosis to prevention and treatment. The questions considered relate to a wide range of issues, such as: How do I diagnose AKI? How can I protect the kidney in clinical practice? How do I manage patients with AKI? When should I initiate and how do I pe…
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Other Authors
Oudemans-van Straaten, Heleen M
Forni, Lui G
Groeneveld, A.B. Johan
Bagshaw, Sean M
Joannidis, Michael
Responsibility
Heleen M. Oudemans-van Straaten, Lui G. Forni, A.B. Johan Groeneveld, Sean M. Bagshaw, Michael Joannidis, editors
Place of Publication
Cham
Publisher
Springer
Date of Publication
c2015
Physical Description
1 online resource (viii, 286 p. : 22 illus., 19 illus. in color)
ISBN
9783319173894
9783319173887 (print ed.)
Subjects (MeSH)
Acute Disease
Acute Kidney Injury
Critical Care - methods
Renal Replacement Therapy
Abstract
This practical guide provides the reader with answers to important clinically relevant questions regarding the evaluation and management of acute kidney injury (AKI). All aspects of critical care nephrology are covered, from pathophysiology and diagnosis to prevention and treatment. The questions considered relate to a wide range of issues, such as: How do I diagnose AKI? How can I protect the kidney in clinical practice? How do I manage patients with AKI? When should I initiate and how do I perform renal replacement therapy (RTT)? Which type of RTT is most appropriate for my patient? Should I give specific nutrients? In addition to providing practical guidelines and treatment algorithms, the book includes calculators for continuous RRT and anticoagulant dosing. The authors are internationally renowned experts in the fields of Intensive Care Medicine and Nephrology, and all contributions are written in a clear and concise style and have been peer reviewed. Acute Nephrology for the Critical Care Physician will serve as a very useful source for intensivists, internists, anesthesiologists, and nephrologists involved in the management and treatment of critically ill patients at risk of or affected by AKI.
Contents
Part I. Acute Kidney Injury -- 1 AKI: Defi nitions and Clinical Context -- 2 Epidemiology of AKI -- 3 Renal Outcomes After Acute Kidney Injury -- 4 Etiology and Pathophysiology of Acute Kidney Injury -- 5 Acid–Base -- 6 Kidney-Organ Interaction -- 7 Acute Kidney Injury in Pregnancy -- Part II. Diagnosis of AKI -- 8 Classical Biochemical Work Up of the Patient with Suspected AKI -- 9 Acute Kidney Injury Biomarkers -- 10 Renal Imaging in Acute Kidney Injury -- Part III. Prevention and Protection -- 11 Prevention of AKI and Protection of the Kidney -- Part IV. Renal Replacement Therapy -- 12 Timing of Renal Replacement Therapy -- 13 Dose of Renal Replacement Therapy in AKI -- 14 Type of Renal Replacement Therapy -- 15 Anticoagulation for Continuous Renal Replacement Therapy -- 16 Metabolic Aspects of CRRT -- 17 Continuous Renal Replacement Therapy in Sepsis: Should We Use High Volume or Specific Membranes? -- 18 Drug Removal by CRRT and Drug Dosing in Patients on CRRT -- 19 Renal Replacement Therapy for Intoxications -- 20 Pediatric CRRT -- 21 Operational and Nursing Aspects.
Format
e-Book
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Online
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Adipose tissue and adipokines in health and disease

https://libcat.nshealth.ca/en/permalink/provcat33256
Giamila Fantuzzi, Theodore Mazzone, editors. (Second edition) --New York: Humana Press , c2014.
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The field of adipose tissue biology has been expanding at a very rapid pace in the last few years. Numerous advances have been made since publication of the first edition of this book, in terms of basic adipocyte biology, understanding of the determinants of obesity, distribution of body fat and weight loss, as well as the mechanisms linking excess adiposity to various co-morbidities. Adipose Tissue and Adipokines in Health and Disease, Second Edition contains updated chapters from the previous…
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Other Authors
Fantuzzi, Giamila
Mazzone, Theodore
Responsibility
Giamila Fantuzzi, Theodore Mazzone, editors
Edition
Second edition
Place of Publication
New York
Publisher
Humana Press
Date of Publication
c2014
Physical Description
1 online resource (xxvi, 372 pages)
Series
Nutrition and Health
Series Title
Nutrition and health (Totowa, N.J.)
ISBN
9781627037709 (electronic bk.)
9781627037693
Subjects (MeSH)
Adipocytes - physiology
Adipose Tissue - physiology
Obesity - complications
Obesity - etiology
Subjects (LCSH)
Adipose tissues
Fat cells
Adipocytes
Abstract
The field of adipose tissue biology has been expanding at a very rapid pace in the last few years. Numerous advances have been made since publication of the first edition of this book, in terms of basic adipocyte biology, understanding of the determinants of obesity, distribution of body fat and weight loss, as well as the mechanisms linking excess adiposity to various co-morbidities. Adipose Tissue and Adipokines in Health and Disease, Second Edition contains updated chapters from the previous volume but as the field has evolved, some areas covered in the first edition have been refocused to address the new knowledge. The volume is divided in four sections: the first two deal with basic adipose tissue and adipokine biology, while the last two address the problem of obesity and alterations in adipose tissue function from an epidemiological and clinical standpoint. The chapters are written by experts in their fields and include the most up to date scientific information. Adipose Tissue and Adipokines in Health and Disease, Second Edition is a useful resource for physicians interested in adipose tissue biology and basic scientists who want to know more about applied aspects of the field. The book targets endocrinologists, residents and fellows, internists, nutritionists and general practitioners who are exposed to an ever-expanding obese population.
Contents
Adipose Tissue: Structure and Function -- Adipose Tissue in Evolution -- Adipose Stem Cells and Adipogenesis -- Adipose Stem Cells and Adipogenesis -- Metabolism of White Adipose Tissue -- Bad Fat or Just More Fat? Murine Models of Metabolically Healthy Obesity -- The Aging Adipose Organ: Lipid Redistribution, Inflammation, and Cellular Senescence -- Adipokines: Leptin and Adiponectin in the Regulation of Inflammatory and Immune Responses -- Adipose Tissue Inflammation and Adipocyte Dysfunction in Obesity -- Adipose Tissue Inflammation -- Endoplasmic Reticulum Stress and Adipose Tissue Function -- Autophagy in White Adipose Tissue -- Obesity and Micronutrient Deficiencies -- Obesity -- Epidemiology of Obesity in Children -- Genetics of Obesity -- Epigenetics of Obesity -- Consequences of Rapid Weight Loss -- Adipose Tissue and Disease -- Human Lipodystrophy: An Update in Molecular Genetics and Possible Mechanisms of Fat Loss -- Adipose Tissue and Type 2 Diabetes Mellitus -- Adipokines in Nonalcoholic Fatty Liver Disease -- Obesity and Cardiovascular Disease -- Respiratory Diseases in Obesity -- Adiposity and Kidney Disease -- Obesity and Joint Disease -- Obesity and Colon and Postmenopausal Breast Cancer.
Format
e-Book
Location
Online
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Advances in Geroscience

https://libcat.nshealth.ca/en/permalink/provcat39908
Felipe Sierra, Ronald Kohanski, editors. (1st ed.) --Cham: Springer , c2016.
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This book provides the first comprehensive overview of a new scientific discipline termed Geroscience. Geroscience examines the molecular and cellular mechanisms that might explain why aging is the main risk factor for most chronic diseases affecting the elderly population. Over the past few decades, researchers have made impressive progress in understanding the genetics, biology and physiology of aging. This book presents vital research that can help readers to better understand how aging is a…
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Other Authors
Sierra, Felipe
Kohanski, Ronald
Responsibility
Felipe Sierra, Ronald Kohanski, editors
Edition
1st ed.
Place of Publication
Cham
Publisher
Springer
Date of Publication
c2016
Physical Description
1 online resource (xxiii, 622 p. : 39 illus.)
ISBN
9783319232461
9783319232454 (print ed.)
Subjects (MeSH)
Aging - physiology
Chronic Disease
Geriatrics
Risk Factors
Abstract
This book provides the first comprehensive overview of a new scientific discipline termed Geroscience. Geroscience examines the molecular and cellular mechanisms that might explain why aging is the main risk factor for most chronic diseases affecting the elderly population. Over the past few decades, researchers have made impressive progress in understanding the genetics, biology and physiology of aging. This book presents vital research that can help readers to better understand how aging is a critical malleable risk factor in most chronic diseases, which, in turn, could lead to interventions that can help increase a healthy lifespan, or "healthspan". The book begins with an analysis of the Geroscience hypothesis, as well as the epidemiological underpinnings that define aging as a candidate main risk factor for most chronic diseases. Next, each chapter focuses on one particular disease, or group of diseases, with an emphasis on how basic molecular and cellular biology might explain why aging is a major risk factor for it. Coverage in the book includes: cancer, cardiovascular disease, dementias, stroke, Parkinson's and Alzheimer's diseases, osteoporosis, arthritis, diabetes asthma, emphysema, kidney disease, vision impairment, and AIDS/HIV. It finishes with a chapter on pain in the elderly and an overview of future steps needed to bring the newly acquired knowledge into the clinic and the public at large.
Contents
The Geroscience Hypothesis: Is It Possible to Change the Rate of Aging? / Steven N. Austad -- Etiological Role of Aging in Chronic Diseases: From Epidemiological Evidence to the New Geroscience / Linda P. Fried and Luigi Ferrucci -- The Impact of Aging on Cancer Progression and Treatment / Shenghui He and Norman E. Sharpless -- The Impact of Cancer Treatments on Aging / Changhan Lee and Valter Longo -- Cardiovascular Disease and Aging / Ying Ann Chiao, Edward Lakatta, Zoltan Ungvari, Dao-Fu Dai and Peter Rabinovitch -- The Impact of Aging on Ischemic Stroke / Farida Sohrabji -- Parkinson's Disease and Aging / Julie K. Andersen -- The Role of Aging in Alzheimer's Disease / Geoffrey A. Kerchner and Tony Wyss-Coray -- Aging and the Bone-Muscle Interface / Simon Melov and Clifford J. Rosen -- Osteoporosis and Mechanisms of Skeletal Aging / Julie Glowacki and Tamara Vokes -- Osteoarthritis in the Elderly / Richard F. Loeser and Martin Lotz -- Diabetes and Aging / Nicolas Musi and Andrzej Bartke -- Renal Aging and Transplantation / John P. Higgins and Stuart K. Kim -- Asthma and Aging / Nicola A. Hanania and Paula Busse -- Aging in COPD and Idiopathic Pulmonary Fibrosis / Cecilia Sanchez -- Age-Related Macular Degeneration and Vision Impairment / Jayakrishna Ambati and Charles Wright -- HIV and Aging: Parallels and Synergistic Mechanisms Leading to Premature Disease and Functional Decline / Anna Hearps, Katherine Schafer, Kevin High and Alan Landay -- Pain in the Elderly / Roger B. Fillingim, Dennis C. Turk and Robert P. Yezierski -- The Way Forward / translation: James L. Kirkland.
Format
e-Book
Location
Online
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Advances in Image-Guided Urologic Surgery

https://libcat.nshealth.ca/en/permalink/provcat38950
Joseph C. Liao, Li-Ming Su, editors. --New York, NY: Springer , c2015.
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This book provides an overview of the current state-of-art in combining advances in biomedical imaging with intraoperative navigation and preoperative planning for urologic surgery. These advances hold great promise in improving diagnostic and therapeutic urologic interventions to improve patient outcomes. Leading experts in this exciting emerging field covers early clinical and pre-clinical applications of optical, ultrasound, cross-sectional, and computer-assisted imaging in urologic surgery.…
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Other Authors
Liao, Joseph C
Su, Li-Ming
Responsibility
Joseph C. Liao, Li-Ming Su, editors
Place of Publication
New York, NY
Publisher
Springer
Date of Publication
c2015
Physical Description
1 online resource (xvi, 289 p. : 135 illus., 119 illus. in color)
ISBN
9781493914500
9781493914494 (print ed.)
Subjects (MeSH)
Minimally Invasive Surgical Procedures
Surgery, Computer-Assisted
Urologic Diseases - surgery
Urologic Surgical Procedures
Abstract
This book provides an overview of the current state-of-art in combining advances in biomedical imaging with intraoperative navigation and preoperative planning for urologic surgery. These advances hold great promise in improving diagnostic and therapeutic urologic interventions to improve patient outcomes. Leading experts in this exciting emerging field covers early clinical and pre-clinical applications of optical, ultrasound, cross-sectional, and computer-assisted imaging in urologic surgery. Advances in Image-Guided Urologic Surgery provides a unique and valuable resource for audience with clinical and research interest in minimally invasive surgery, endourology, urologic oncology, imaging, and biomedical engineering.
Contents
Part I. Optical Imaging Technologies -- Endoscopic Fluorescence Imaging of Bladder Cancer: Photodynamic Diagnosis and Confocal Laser Endomicroscopy -- Narrow Band Imaging for Urothelial Cancer -- Optical Coherence Tomography in Bladder Carcinoma -- Optical Coherence Tomography for Prostate Cancer and Beyond -- Fluorescence Image-Guided Robotic Surgery -- Multiphoton Microscopy in Urologic Surgery -- Hyperspectral Imaging of Renal Oxygenation (Near-Infrared Tissue Oximetry for Renal Ischemia) -- Light Reflectance Spectroscopy and Autofluorescence (Kidney and Prostate) -- Part II. Ultrasound-Guided Interventions -- Intraoperative Doppler Ultrasound During Robotic Surgery -- TRUS of the Prostate: State of the Art -- Ultrasound-Guided Prostate Cryotherapy -- Endoluminal Ultrasonography -- Part III. Cross-Sectional Image-Guided Interventions -- Multiparametric Magnetic Resonance Imaging for Prostate Cancer -- MR-Guided Prostate Interventions -- CT-Guided Renal Ablation- MR-Guided Renal Ablation -- Part IV. On the Horizon -- Augmented Reality for Percutaneous Renal Interventions -- Image Guidance in Robotic Assisted Renal Surgery -- Urologic Surgery Training Using Computer-Assisted Simulators -- Molecular Imaging in Urology.
Format
e-Book
Location
Online
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Aesthetic Plastic Surgery of the Abdomen

https://libcat.nshealth.ca/en/permalink/provcat39816
Alberto Di Giuseppe, Melvin A. Shiffman, editors. --Cham: Springer , c2016.
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This comprehensive book covers anatomy, recent techniques, postoperative care, possible complications, and outcomes in aesthetic surgery of the abdomen. The extensive section on aesthetic procedures includes many important innovations in abdominoplasty. Detailed consideration is also given to the various potential complications, with guidance on their prevention, diagnosis, and management. The book is written by acknowledged experts in the topics on which they write. It will be of value for res…
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Other Authors
Di Giuseppe, Alberto
Shiffman, Melvin A
Responsibility
Alberto Di Giuseppe, Melvin A. Shiffman, editors
Place of Publication
Cham
Publisher
Springer
Date of Publication
c2016
Physical Description
1 online resource (xv, 556 p. : 454 illus., 446 illus. in color)
ISBN
9783319200040
9783319200033 (print ed.)
Subjects (MeSH)
Abdomen - surgery
Cosmetic Techniques
Reconstructive Surgical Procedures
Surgery, Plastic - methods
Abstract
This comprehensive book covers anatomy, recent techniques, postoperative care, possible complications, and outcomes in aesthetic surgery of the abdomen. The extensive section on aesthetic procedures includes many important innovations in abdominoplasty. Detailed consideration is also given to the various potential complications, with guidance on their prevention, diagnosis, and management. The book is written by acknowledged experts in the topics on which they write. It will be of value for residents and fellows and more experienced surgeons in the fields of plastic surgery, general surgery, cosmetic surgery, and general surgery.
Contents
History -- 1. History of abdominoplasty -- 2. Muscular anatomy of the abdominal wall -- 3. Vascular and neurologic anatomy of the abdominal wall -- 4. Anatomical illustration study of the abdominal wall and fat- techniques -- 5. The impact of the menstrual cycle on intra-operative and postoperative bleeding in abdominoplasty patients -- 6. The umbilical locator -- 7. Scarpa fascia preservation during abdominoplasty -- 8. Medial advancement of infra-umbilical scarpa's fascia improves waistline definition in "Brazilian" abdominoplasty -- 9. Progressive tension sutures in abdominoplasty -- 10. Evolution of the high-superior-tension lipoabdominoplasty: the high tension abdominoplasty -- 11. Lipoabdominoplasty with abdominal definition -- 12."Smile" plication abdominoplasty -- 13. Anchor line abdominoplasty -- 14. Circumferential abdominoplasty -- 15. A paradigm shift for abdominoplasty: transverse hypogastric plication without supraumbilical dissection, unrestricted liposuction, neoumbilicoplasty and low placement of the scar (tulua) -- 16. Abdominoplasty combined with cesarean section: discussion of the evidence -- 17. Lipoabdominoplasty -- 18. Modified combined lipoabdominoplasty without surgical drains -- 19. Vaser lipoabdominoplasty -- 20. Effectiveness and safety of combining laser-assisted liposuction and abdominoplasty -- 21. Abdominal contouring associated with other procedures -- 22. Modified abdominoplasty for patients with prune belly syndrome -- 23. Vaser abdominal contouring -- 24. Abdominoplasty access for desmoid tumor resection in the rectus abdominis muscle -- 25. Abdominal wall repair post hernia in kidney and liver transplantation and after gunshot wound -- 26. Abdominoplasty as the patient impetus for selection of the deep inferior epigastric artery perforator free flap donor site -- 27. Umbilicoplasty without external scar -- postoperative -- 28. Metabolic effect of abdominoplasty in the lipid profile of patients with dyslipidemia -- 29. Weight reduction following abdominoplasty -- 30. Ventilatory function in patients who underwent abdominoplasty with plication of the aponeurosis of the external oblique -- 31. C-reactive protein decrease after postbariatric abdominoplasty- complications -- 32. Complications of abdominoplasty -- 33. Retrospective analysis of never events in panniculectomy and abdominoplasty patients and their financial implications -- 34. Tension suture technique combined with lidocaine-adrenalin-saline-infiltration decreases complications in abdominoplasty -- 35. Acute abdomen after abdominoplasty: differential diagnosis -- 36. The impact of the menstrual cycle on intra-operative and postoperative bleeding in abdominoplasty patients -- 37. Maximizing chemoprophylaxis against venous thromboembolism in abdominoplasty -- 38. A study of postural changes after abdominal rectus plication abdominoplasty -- 39. Abdominoplasty complications and seroma. From prevention to effective treatment -- 40. Delayed complications in abdominoplasty: a case of a ten-year-old abdominoplasty abscess: a case of a 10-year-old abdominoplasty abscess -- 41. Acute esophageal dilation mimicking serious pulmonary complication after post-bariatric abdominoplasty -- 42. Hematological variables and iron status in abdominoplasty after bariatric surgery -- 43. Increased intraoperative bleeding in patients undergoing abdominoplasty after gastroplasty is not due to coagulopathy or vascular anatomic changes: outcomes, satisfaction -- 44. Comparison of short-term surgical outcomes between nhs and private sector abdominoplasty surgery -- 45. Outcomes of traditional cosmetic abdominoplasty in a community setting -- 46. Long-term ultrasonographic evaluation of midline aponeurotic plication during abdominoplasty -- 47. Complications and level of satisfaction after dermolipectomy and abdominoplasty post-bariatric surgery.
Format
e-Book
Location
Online
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AJCC Cancer Staging Atlas : A Companion to the Seventh Editions of the AJCC Cancer Staging Manual and Handbook

https://libcat.nshealth.ca/en/permalink/provcat30955
editors, Carolyn C. Compton .. [et al.]. (2nd ed.) --New York, NY: Springer , c2012.
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Significantly expanded, expertly and beautifully illustrated, The AJCC Cancer Staging Atlas, 2nd Edition, offers more than 600 illustrations created exclusively for this new edition and is fully updated to reflect the concepts discussed in the 7th Edition of both the AJCC Cancer Staging Manual and its companion Handbook. This Atlas illustrates the TNM classifications of all cancer sites and types included in the 7th Edition of the Manual and visually conceptualizes the TNM classifications and s…
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Corporate Author
American Joint Committee on Cancer
Other Authors
Compton, Carolyn C
Responsibility
editors, Carolyn C. Compton .. [et al.]
Edition
2nd ed.
Place of Publication
New York, NY
Publisher
Springer
Date of Publication
c2012
Physical Description
1 online resource (xi, 637 p. : 485 ill., 42 ill. in color)
ISBN
9781461420804
Subjects (MeSH)
Neoplasm Staging - Atlases
Neoplasms - classification
Subjects (LCSH)
Oncology
Pathology
Abstract
Significantly expanded, expertly and beautifully illustrated, The AJCC Cancer Staging Atlas, 2nd Edition, offers more than 600 illustrations created exclusively for this new edition and is fully updated to reflect the concepts discussed in the 7th Edition of both the AJCC Cancer Staging Manual and its companion Handbook. This Atlas illustrates the TNM classifications of all cancer sites and types included in the 7th Edition of the Manual and visually conceptualizes the TNM classifications and stage groupings. Specifically designed for simplicity and precision, the drawings have been verified through multi-disciplinary review to ensure accuracy and relevancy for clinical use. Every illustration provides detailed anatomic depictions to clarify critical structures and to allow the reader to instantly visualize the progressive extent of malignant disease. In addition, nodal maps are included for each site, appropriate labeling has been incorporated to identify significant anatomic structures, and each illustration is accompanied by an explanatory legend. The AJCC Cancer Staging Atlas, 2nd Edition, is an official publication of the American Joint Committee on Cancer, the recognized international leader in state-of-the-art information on cancer staging. This Atlas has been created as a companion to the updated 7th Edition of the AJCC Cancer Staging Manual, which continues to disseminate the importance of anatomical and pathological staging in the management of cancer. This state-of-the-art, invaluable 2nd Edition includes a CD containing PowerPoint slides of all illustrations, additional color, and a user-friendly, easy-to-read layout. The AJCC Cancer Staging Atlas, 2nd Edition will serve as an indispensable reference for clinicians, registrars, students, trainees, and patients.
Contents
Purposes and Principles of Cancer Staging -- Cancer Survival Analysis -- Lip and Oral Cavity -- Pharynx -- Larynx -- Nasal Cavity and Paranasal Sinuses -- Major Salivary Glands (Parotid, Submandibular, and Sublingual) -- Thyroid -- Mucosal Melanoma of the Head and Neck -- Esophagus and Esophagogastric Junction -- Stomach -- Small Intestine -- Appendix -- Colon and Rectum -- Anus -- Gastrointestinal Stromal Tumor -- Neuroendocrine Tumors -- Liver -- Intrahepatic Bile Ducts -- Gallbladder -- Perihilar Bile Ducts -- Distal Bile Duct -- Ampulla of Vater -- Exocrine and Endocrine Pancreas -- Lung -- Pleural Mesothelioma -- Bone -- Soft Tissue Sarcoma -- Cutaneous Squamous Cell Carcinoma and Other Cutaneous Carcinomas -- Merkel Cell Carcinoma -- Melanoma of the Skin -- Breast -- Vulva -- Vagina -- Cervix Uteri -- Corpus Uteri -- Ovary and Primary Peritoneal Carcinoma -- Fallopian Tube -- Gestational Trophoblastic Tumors -- Penis -- Prostate -- Testis -- Kidney -- Renal Pelvis and Ureter -- Urinary Bladder -- Urethra -- Adrenal -- Hodgkin and Non-Hodgkin Lymphomas -- Primary Cutaneous Lymphomas.
Format
e-Book
Location
Online
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Alagille Syndrome : Pathogenesis and Clinical Management

https://libcat.nshealth.ca/en/permalink/provcat42597
Binita M. Kamath, Kathleen M. Loomes, editors. --Cham: Springer , c2018.
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This text provides a concise yet comprehensive overview of Alagille syndrome. The book reviews the pathophysiology and genetics of the disorder, discusses recent molecular advances and its impact on diagnostics, and describes management challenges and strategies. The text also touches upon future treatment options. Written by experts in the field, Alagille Syndrome: Pathogenesis and Clinical Management is a valuable resource for physicians and researchers dealing with this disorder, one that wi…
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Other Authors
Kamath, Binita M.
Loomes, Kathleen M.
Responsibility
Binita M. Kamath, Kathleen M. Loomes, editors
Place of Publication
Cham
Publisher
Springer
Date of Publication
c2018
Physical Description
1 online resource (xiv, 198 p.) : 41 illus., 31 illus. in color
ISBN
9783319945712
9783319945705 (print ed.)
9783319945729 (print ed.)
Subjects (MeSH)
Alagille Syndrome
Specialty
Gastroenterology
Abstract
This text provides a concise yet comprehensive overview of Alagille syndrome. The book reviews the pathophysiology and genetics of the disorder, discusses recent molecular advances and its impact on diagnostics, and describes management challenges and strategies. The text also touches upon future treatment options. Written by experts in the field, Alagille Syndrome: Pathogenesis and Clinical Management is a valuable resource for physicians and researchers dealing with this disorder, one that will help guide patient management and stimulate investigative efforts.
Contents
The Alagille Syndrome: Overview and Introduction -- Bile Duct Development and the Notch Signaling Pathway -- Genetics of Alagille Syndrome -- Liver Disease in Alagille Syndrome -- Transplant Considerations in Alagille Syndrome -- Cardiac, Aortic, and Pulmonary Vascular Involvement in Alagille Syndrome -- Vascular Manifestations in Alagille Syndrome -- The Renal Sequelae of Alagille Syndrome as a Product of Altered Notch Signaling During Kidney Development -- Skeletal Involvement in Alagille Syndrome -- Immune Dysregulation in Alagille Syndrome: A Feature of the Evolving Phenotype -- Health-Related Quality of Life and Neurocognition in Alagille Syndrome -- Future Therapeutic Approaches for Alagille Syndrome.
Format
e-Book
Location
Online
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ALERT – adverse late effects of cancer treatment. Volume 2, Normal tissue specific sites and systems

https://libcat.nshealth.ca/en/permalink/provcat33418
Philip Rubin, Louis S. Constine, Lawrence B. Marks, editors. --Heidelberg: Springer , c2014.
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The literature on the late effects of cancer treatment is widely scattered in different journals since all major organ systems are affected and management is based on a variety of medical and surgical treatments. The aim of ALERT Adverse Late Effects of Cancer Treatment is to offer a coherent multidisciplinary approach to the care of cancer survivors. The central paradigm is that cytotoxic multimodal therapy results in a perpetual cascade of events that affects each major organ system different…
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Other Authors
Rubin, Philip
Constine, Louis S
Marks, Lawrence B
Responsibility
Philip Rubin, Louis S. Constine, Lawrence B. Marks, editors
Alternate Title
Adverse late effects of cancer treatment
Place of Publication
Heidelberg
Publisher
Springer
Date of Publication
c2014
Physical Description
1 online resource (xx, 700 pages)
Series
Medical radiology. Radiation oncology
Series Title
Medical radiology (Series)
ISBN
9783540758631 (electronic bk.)
9783540758624
Subjects (MeSH)
Antineoplastic Agents - adverse effects
Radiotherapy - adverse effects
Radiation Injuries
Subjects (LCSH)
Cancer - Treatment - Complications
Neoplasms - therapy - complications
Abstract
The literature on the late effects of cancer treatment is widely scattered in different journals since all major organ systems are affected and management is based on a variety of medical and surgical treatments. The aim of ALERT Adverse Late Effects of Cancer Treatment is to offer a coherent multidisciplinary approach to the care of cancer survivors. The central paradigm is that cytotoxic multimodal therapy results in a perpetual cascade of events that affects each major organ system differently and is expressed continually over time. Essentially, radiation and chemotherapy are intense biologic modifiers that allow for cancer cure and cancer survivorship but accelerate senescence of normal tissues and increase the incidence of age-related diseases and second malignant tumors. Volume 2 of this two-volume work comprehensively documents potential late effects in all the normal tissue anatomic sites in the human body. The detection, diagnosis, management and prevention of effects are all considered in detail, and prognostic outcomes are discussed. Radiation risk factors and interactions with chemotherapy effects are clearly presented. The text is accompanied by numerous supportive illustrations and tables.
Contents
Brain and Cranial Nerves -- Spinal Cord and Peripheral Nervous System -- Neuroendocrine Complications of Radiation and Cancer Therapy -- Eye and Orbit -- Radiation-Induced Ototoxicity -- Late Oral Adverse Effects of Cancer Treatments -- Upper Respiratory and Digestive System: Pharynx, Larynx, and Xerostomia -- Thyroid -- Skin Surface, Dermis, and Wound Healing -- Breast Cancer -- Lung -- Heart, Coronary Arteries, Aorta and Great Vessels, Arteries and Veins, Microcirculation -- Esophagus -- Stomach, Small and Large Intestines -- Liver -- Adverse Late Effects of Radiation Treatment in the Pancreas -- Kidney and Ureter -- Urinary Bladder -- Prostate, Seminal Vesicle, Penis, and Urethra -- The Testes -- Ovary, Uterus (Fallopian Tube, Cervix), Vagina, and Vulva -- Radiation Induced Rectal Toxicity -- Musculoskeletal System: Growing Endochondral Bone, Mature Osseous, Muscle (Striated), and Soft Tissue Mesenchyme -- Hematopoietic System -- Late Effects of Hematopoietic Cell Transplantation Including Total Body Irradiation -- Lymph Nodes, Thymus, Spleen, and Lymphatics.
Format
e-Book
Location
Online
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Amyloid and Related Disorders : Surgical Pathology and Clinical Correlations

https://libcat.nshealth.ca/en/permalink/provcat39337
Maria M. Picken, Guillermo A. Herrera, Ahmet Dogan, editors. (Second edition) --Cham: Springer International Publishing : Imprint: Humana Press , c2015.
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Online
The second edition of this text presents an overview of the most recent developments in this area including clinical presentation, etiology, pathogenesis, and differential diagnosis. The rationale for various therapies, including transplantation, is discussed and tissue diagnosis (its pitfalls and strategies for avoiding them) and laboratory support are included. The involvement of all major organ systems including renal/genitourinary, cardiac, gastrointestinal, pulmonary, peripheral nerve/cent…
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Other Authors
Picken, Maria M
Herrera, Guillermo A
Dogan, Ahmet
Responsibility
Maria M. Picken, Guillermo A. Herrera, Ahmet Dogan, editors
Edition
Second edition
Place of Publication
Cham
Publisher
Springer International Publishing : Imprint: Humana Press
Date of Publication
c2015
Physical Description
1 online resource (xix, 542 p. : 391 illus., 345 illus. in color)
Series Title
Current clinical pathology
ISBN
9783319192949
9783319192932 (print ed.)
ISSN
2197-781X
Subjects (MeSH)
Amyloid - adverse effects
Amyloidosis - diagnosis
Amyloidosis - pathology
Amyloidosis - therapy
Abstract
The second edition of this text presents an overview of the most recent developments in this area including clinical presentation, etiology, pathogenesis, and differential diagnosis. The rationale for various therapies, including transplantation, is discussed and tissue diagnosis (its pitfalls and strategies for avoiding them) and laboratory support are included. The involvement of all major organ systems including renal/genitourinary, cardiac, gastrointestinal, pulmonary, peripheral nerve/central nervous system, soft tissue, skin, lymph node/spleen and bone marrow pathology is also covered. Amyloid and Related Disorders, Second Edition will be invaluable to specialized and general pathologists as well as cytopathologists. Other medical professionals may also benefit from this concise update on the systemic amyloidoses.
Contents
[publisher supplied] Introduction/general -- Aspects of the history and nomenclature of amyloid and amyloidosis -- Amyloid diseases at the molecular level: general overview and focus on AL amyloidosis -- AA amyloidosis -- Non-Immunoglobulin and non-AA amyloidoses -- The hereditary amyloidoses -- Dialysis-associated amyloidosis -- Localized amyloidoses and amyloidoses associated with aging outside the central nervous system -- Central nervous system amyloid -- Non-amyloid protein deposits -- Differential diagnosis of amyloid in surgical pathology: organized deposits and other material in the differential diagnosis of amyloidosis -- Light /heavy chain deposition disease as a systemic disease -- Glomerulonephritis with non-organized monoclonal immunoglobulin deposits -- Pathologies of renal and systemic intracellular paraprotein storage: crystalopathies and beyond -- Diagnosis -- Diagnosis of amyloid using Congo red: polarized and fluorescence -- Thioflavin T stain for amyloid detection -- Fat tissue analysis in the management of patients with systemic amyloidosis -- Generic diagnosis of amyloid: recent developments and summary of current recommendations -- Amyloid typing on formalin-fixed paraffin sections by immunohistochemistry: experience from two large referral centers -- Options for amyloid typing in renal pathology: the advantages of frozen section immunofluorescence -- Amyloid typing by immuno-electron microscopy -- Classification of amyloidosis by mass spectrometry-based proteomics -- Summary and practical recommendation regarding amyloid typing using antibody-based and proteomic methods -- Ancillary studies of amyloidosis -- Laboratory support for diagnosis of amyloidosis -- Bone marrow biopsy and its utility in the diagnosis of AL amyloidosis and other plasma cell dyscrasias -- Molecular methods for the diagnosis of hereditary amyloidosis -- Radiologic support for diagnosis and monitoring of amyloidosis: established techniques and recent developments -- Organ involvement in amyloidoses -- Amyloidoses of the Kidney and Genitourinary tract -- Cardiac amyloidosis -- Amyloidosis of the Gastrointestinal tract and Liver -- Peripheral nerve amyloidosis -- Amyloidoses of the Pulmonary and upper respiratory tract -- Amyloidoses involving the skin -- Clinical issues and therapy -- Clinico-pathologic issues in patients with amyloidosis -- Solid organ transplantation in amyloidosis and issues pertaining to domino liver transplantation -- Emerging therapies for amyloidosis -- Clinical trials -- Modern therapies in AA amyloidosis -- Medico legal issues of amyloidosis -- Amyloidosis from the patient's perspective.
Format
e-Book
Location
Online
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Anaesthesia, Pharmacology, Intensive Care and Emergency A.P.I.C.E : Proceedings of the 25th Annual Meeting : International Symposium on Critical Care Medicine

https://libcat.nshealth.ca/en/permalink/provcat39665
Antonino Gullo, editor. --Milan: Springer Milan , c2014.
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The APICE 2013 yearbook examines recent advances in various aspects of critical care medicine and highlights the importance of effective communication among researchers, scientists, and clinicians. Among the many topics addressed are trauma care organization, the management of patients with cardiovascular, kidney, and lung disorders, issues relating to severe infections and sepsis, and the humanization of end of life care. The overriding goal of the book is to provide guidance and stimulate fur…
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Other Authors
Gullo, Antonino
Responsibility
Antonino Gullo, editor
Alternate Title
APICE 25
Former Title
Anesthesia, Pain, Intensive Care and Emergency A.P.I.C.E.
Place of Publication
Milan
Publisher
Springer Milan
Date of Publication
c2014
Physical Description
1 online resource (xiii, 260 p. : 28 illus., 10 illus. in color)
ISBN
9788847055162
9788847055155 (print ed.)
Subjects (MeSH)
Anesthesia - methods
Critical Care - methods
Pain - drug therapy
Critical Care
Emergency Medicine
Critical Care - Congresses
Abstract
The APICE 2013 yearbook examines recent advances in various aspects of critical care medicine and highlights the importance of effective communication among researchers, scientists, and clinicians. Among the many topics addressed are trauma care organization, the management of patients with cardiovascular, kidney, and lung disorders, issues relating to severe infections and sepsis, and the humanization of end of life care. The overriding goal of the book is to provide guidance and stimulate further thought on how professional performance in critical care medicine can be improved. "Triple B" translational research, from the bench to the bedside and back again (via the translation of clinical observations into new research questions), will play a major role in this context, and is particularly discussed in the chapter about sepsis and organ dysfunction. There is no doubt that the transfer of far-reaching and dynamic developments in molecular and cellular biology into clinical practice will be a key component in delivering the care required by individual patients.
Contents
Part I, Advances on Intensive and Critical Care Medicine -- 1 Combining Clinical and technology in Critical care Medicine -- 2 Ultrasound in Critical Care -- 3 Assessment and Management of Circulatory Failure -- 4 Simulation in Critical Care -- Part II, Trauma -- 5 Trauma Care Organization and Priorities -- Part III, Cardiovascular System -- 6 Cardiovascular Risk in non Cardiac Surgery -- Part IV Kidney -- 7 CRRT: Challenges and Evidence -- Part V, Lung -- 8 Old and New Strategies on Artificial Ventilation in ARDS Patients -- 9 Postoperative Respiratory Complications -- 10 Minimally Invasive Surgical Procedures in Thoracic Surgery -- Part VI, Severe Infections, Sepsis and MODS -- 11 Diagnosis of Ventilator Associated Pneumonia (VAP) -- 12 Rationale of Antibiotics anti MRSA in Pneumonia -- 13 The Role of Microbiology for Diagnosis of Fungal Infections -- 14 Spectrum of Sepsis and MODS -- 15 Immunoglobulin as Adjunctive Therapy in Sepsis -- Part VII, Cardiac Arrest: Optimization of Current Protocols -- 16 Determinants for More Efficient Defibrillation Waveforms -- 17 Post-resuscitation Hypothermia and Monitoring -- Part VIII, Humanization -- 18 Palliative Care in Pediatrics -- 19 End of Life Care.
Format
e-Book
Location
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Anaesthesia, Pharmacology, Intensive Care and Emergency Medicine A.P.I.C.E. : Proceedings of the 23rd Postgraduate Course in Critical Care Medicine Catania, Italy : November 5-7, 2010

https://libcat.nshealth.ca/en/permalink/provcat30800
Antonino Gullo (ed.). --Milan: Springer , c2011.
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Online
Available Online
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Other Authors
Gullo, Antonino
Responsibility
Antonino Gullo (ed.)
Alternate Title
APICE 23
Former Title
Anesthesia, Pain, Intensive Care and Emergency A.P.I.C.E.
Place of Publication
Milan
Publisher
Springer
Date of Publication
c2011
Physical Description
1 online resource (380 p.)
ISBN
9788847020146
Subjects (MeSH)
Anesthesia - methods
Critical Care - methods
Pain - drug therapy
Critical Care
Emergency Medicine
Critical Care - Congresses
Subjects (LCSH)
Anesthesiology
Critical care medicine
Contents
Continuing Medical Education: Can I Think what I Read? -- Clinical Pharmacology: Pharmacological Manipulation in ICU. Kidney: Renal Injury. Ventilation: Adult and Paediatric:Respiratory Mechanics: Principles, Utility and Advances. Capnometry/Capnography in Prehospital Cardiopulmonary Resuscitation. Weaning from Mechanical Ventilation. Ventilatory Strategies in Acute Lung Injury. Mechanical Ventilation beyond the PICU -Cardiovascular Monitoring: The NEXFIN Monitor A Totally Non-Invasive Cardiac Output Monitor. Doppler Echocardiography in ICU Patients: Does It Improve Outcome? -- Management of Cardiac Arrest:Mild Therapeutic Hypothermia after Cardiac Arrest. Nasopharyngeal Cooling during Cardiopulmonary Resuscitation. Amplitude Spectrum Area as a Predictor of Successful Defibrillation Advances in Experimental and Clinical Research: Physiopathology and Severity of Post-Resuscitation Myocardial Dysfunction: Effects of Sodium-Hydrogen Exchanger Isoform-1 (NHE-1) Inhibitors and Erythropoietin. Experimental Treatment for Preservation of Mechanically Competent Cardiac Activity following Cardiac Arrest. Erythropoietin Facilitates Return of Spontaneous Circulation and Survival in Victims of Out-of-Hospital Cardiac Arrest -- Infections, Sepsis and Organ Dysfunction: Pathophysiology of Resistance amongst Aerobic Gram-negative Bacilli in Particular Acinetobacter Species. What Have we Learned from the Surviving Sepsis Campaign? Source Control. Immunoglobulins in Sepsis. Extracorporeal Endotoxin Removal in Sepsis. Perioperative Medicine: Perioperative Medicine An Introduction. Neuraxial Analgesia for Caesarean and Vaginal Delivery and Childhood Learning Disabilities. Off-label Drugs in Perioperative Medicine: Clonidine. Spinal Cord Stimulation. Cost Effectiveness of Spinal Cord Stimulation in Management of Severe Angina. Spinal Cord Stimulation:Clinical Assessment and Diagnostic Procedures in Neurotrauma. Disaster Medicine: Disaster Preparedness. Medical Emergency Response in Toxicological Mass Casualty. Quality of Care: Telemedicine to Improve Care in the Critically Ill. Professionalism, Quality of Care and Pay-for-Performance Services.
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e-Book
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Anesthesia and Perioperative Care for Organ Transplantation

https://libcat.nshealth.ca/en/permalink/provcat41225
Kathirvel Subramaniam, Tetsuro Sakai, editor. --New York, NY: Springer , 2017.
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This comprehensive textbook, covering all aspects of the perioperative management of patients undergoing organ transplantation, serves as the standard reference for clinicians who care for transplant patients on a day-to-day basis as well as those who encounter organ transplantation only occasionally in their clinical practice. Anesthesia and Perioperative Care for Organ Transplantation covers transplantation of the heart, lung, liver, pancreas, and kidney, as well as multivisceral and composit…
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Other Authors
Subramaniam, Kathirvel
Sakai, Tetsuro
Responsibility
Kathirvel Subramaniam, Tetsuro Sakai, editor
Place of Publication
New York, NY
Publisher
Springer
Date of Publication
2017
Physical Description
1 online resource (xxiii, 586 pages) : 204 illus., 179 illus. in color
ISBN
9781493963775
9781493963751 (print ed.)
Subjects (MeSH)
Anesthesia
Anesthetics - administration & dosage
Organ Transplantation
Perioperative Care
Abstract
This comprehensive textbook, covering all aspects of the perioperative management of patients undergoing organ transplantation, serves as the standard reference for clinicians who care for transplant patients on a day-to-day basis as well as those who encounter organ transplantation only occasionally in their clinical practice. Anesthesia and Perioperative Care for Organ Transplantation covers transplantation of the heart, lung, liver, pancreas, and kidney, as well as multivisceral and composite tissue graft transplantations. For each kind of transplantation, the full spectrum of perioperative considerations is addressed: preoperative preparation, intraoperative anesthesia management, surgical techniques, and postoperative care. Each chapter contains evidence-based recommendations, relevant society guidelines, management algorithms, and institutional protocols as tables, flow diagrams, and figures. Photographs demonstrating surgical techniques, anesthesia procedures, and perfusion management are included. Anesthesia and Perioperative Care for Organ Transplantation is for anesthesiologists and critical care physicians; transplantation surgeons; nurse anesthetists; ICU nurses; and trainees.
Contents
Part I: General Topics -- 1. Ethical Considerations for Organ Transplantation -- 2. Prevention of Perioperative Infections in Organ Transplant Recipients -- 3. Donation after Cardiac Death -- 4. Living Related Organ Transplantations -- 5. Intensive Care of the Deceased Multiorgan Donor: One Donor, Nine Lives -- 6. Anesthetic Management of Donor Organ Retrieval in a Multiorgan Donor -- Part II: Lung Transplantation -- 7. Preoperative Evaluation and Preparation for Lung Transplantation -- 8. Bilateral Sequential Lung Transplantation: What the Anesthesiologist Needs to Know About the Surgical Approach -- 9. Anesthetic Management for Lung Transplantation -- 10. Postoperative Critical Care of Lung Transplant Patients -- Part III: Heart Transplantation -- 11. Heart Transplant Patient Selection and Preparation -- 12. Surgical Techniques of Heart Transplantation and Heart-Lung Transplantation -- 13. Anesthetic Management of Cardiac Transplantation -- 14. Postoperative Care of Heart Transplant Patients -- Part IV: Special Considerations for Thoracic Transplantation -- 15. Perioperative Management of Pulmonary Hypertension -- 16. Extracorporeal Life Support following Thoracic Organ Transplantation -- 17. Perfusion Management for Thoracic Transplantation Surgery -- 18. Anesthesia for Noncardiac Surgery following Thoracic Organ Transplantation -- Part V: Kidney and Pancreas Transplantation -- 19. Kidney Transplantation: Overview -- 20. Preoperative Recipient Evaluation and Preparation (Kidney) -- 21. Anatomy and Surgical Procedures for Renal and Pancreas Transplantations -- 22. Anesthesia and Intraoperative Management of Renal Transplantation -- 23. Postoperative Care of Renal Transplant Recipients -- 24. Anesthetic Management of Patients Undergoing Pancreas Transplantation -- Part VI: Liver Transplantation -- 25. Liver Transplantation: Historical Perspective -- 26. Preoperative Liver Recipient Evaluation and Preparation -- 27. Anatomy and Surgical Procedures of Liver Transplantation -- 28. Liver Transplantation Anesthesiology -- 29. Postoperative Care of the Liver Transplant Recipient -- 30. Multiorgan Transplantation Including the Liver -- 31. General Anesthesia for the Patient with End-stage Liver Disease and Post Liver Transplantation -- Part VII: Special Issues in Liver Transplantation -- 32. Acute Liver Failure: Perioperative Management -- 33. Portopulmonary Hypertension and Hepatopulmonary Syndrome -- 34. Renal Dysfunction in Hepatic Failure -- 35. Cirrhotic Cardiomyopathy and Liver Transplantation -- 36. Coagulation Abnormality and Its Management -- 37. Simulation: In Anesthesia for Liver Transplantation -- Part VIII: Multivisceral Transplantation -- 38. The Historic Evolution of Intestinal and Multivisceral Transplantation -- 39. Technical Innovation and Visceral Transplantation -- 40. Preoperative Recipient Evaluation for Visceral (Intestine, Intestine/Liver, Multivisceral) Transplantation -- 41. Anesthesia for Multivisceral Transplantation -- 42. Multivisceral Transplantation: Intraoperative Vascular Access Strategy -- 43. Postoperative Management for Visceral (Intestine, Intestine/Liver, and Multivisceral) Transplantation -- Part IX: Composite Tissue Graft Transplantation -- 44. Reconstructive Transplantation: Evolution, Experience, Ethics and Emerging Concepts -- 45. Reconstructive Transplantation: Program, Patient, Protocol, Policy, and Payer Considerations -- 46. Anesthesia for Composite Tissue Allografts -- 47. Postoperative Management of Composite Tissue Graft Transplantation.
Format
e-Book
Location
Online
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