Hormones and the Endocrine System : Textbook of Endocrinology
https://libcat.nshealth.ca/en/permalink/provcat39765
Bernhard Kleine, Winfried G. Rossmanith.
(1st ed.)
--Cham:
Springer
, c2016.
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- Location
- Online
This book focuses on hormones, and on how they are produced in very diverse regions of the body in humans and animals. Hormones exhibiting the same synthesis pathways are not only found in vertebrates, but also in insects, shellfish, spiders, mollusks, and they were present evenat the time of metazoan diversification. The book discusses the different classes of hormones: protein/peptides hormones, steroids and juvenile hormones and hormones like catecholamines, thyroid hormones and melatonin. I…
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- Author
- Kleine, Bernhard
- Other Authors
- Rossmanith, Winfried G
- Responsibility
- Bernhard Kleine, Winfried G. Rossmanith
- Edition
- 1st ed.
- Place of Publication
- Cham
- Publisher
- Springer
- Date of Publication
- c2016
- Physical Description
- 1 online resource (xx, 437 p. : 443 illus., 270 illus. in color)
- ISBN
- 9783319150604
- 9783319150598 (print ed.)
- Subjects (MeSH)
- Endocrine System - physiology
- Hormones
- Abstract
- This book focuses on hormones, and on how they are produced in very diverse regions of the body in humans and animals. Hormones exhibiting the same synthesis pathways are not only found in vertebrates, but also in insects, shellfish, spiders, mollusks, and they were present evenat the time of metazoan diversification. The book discusses the different classes of hormones: protein/peptides hormones, steroids and juvenile hormones and hormones like catecholamines, thyroid hormones and melatonin. It also discusses the different types of hormone receptors, the majority of which are heptahelical G-protein coupled receptors or nuclear receptors. Particular attention is paid to the organs where hormones are synthesized, with specifics on production and release, while a dedicated chapter details hormonal regulation in systems ranging from the very simple to the highly complex. The remarkable kinetics of hormone production is also shown, and the book is rounded out by chapters on the evolution of the endocrine system, the genetics of endocrine diseases and doping.
- Contents
- Introduction -- History of Hormones and Endocrinology -- Part I. Hormone biochemistry -- Hormones: Definitions -- Vertebrate Protein and Peptide Hormones -- Invertebrate protein and peptide hormones -- Hormones from Mevalonate: JH and Steroids -- Hormones Derived by Amino Acid Conversion -- Receptors -- Part II. Endocrine physiology -- Synthesis, Release, and Action -- Endocrine active organs -- Regulatory Patterns -- Endocrine Rock 'n Roll: Rhythms and Secretion -- Evolution of the Endocrine System -- Part III. Hormones and medicine -- Diseases of the Endocrine System -- Boosting Performance: Legally or Not -- Appendix.
- Format
- e-Book
- Location
- Online
Molecular Allergy Diagnostics : Innovation for a Better Patient Management
https://libcat.nshealth.ca/en/permalink/provcat41424
Jörg Kleine-Tebbe, Thilo Jakob, editors.
--Cham:
Springer
, 2017.
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- Location
- Online
This book, based on a recent German publication, offers an overview of basic data and recent developments in the groundbreaking field of molecular allergology. It comprehensively explores the origin and structure of single allergen molecules ("components") and their utility in improving the management of type I, IgE-mediated allergic reactions and disorders like allergic respiratory diseases, food allergies, and anaphylaxis. Highly specific testing, called component-resolved diagnostics, aims t…
- Available Online
- View e-Book
- Other Authors
- Kleine-Tebbe, Jörg
- Jakob, Thilo
- Responsibility
- Jörg Kleine-Tebbe, Thilo Jakob, editors
- Place of Publication
- Cham
- Publisher
- Springer
- Date of Publication
- 2017
- Physical Description
- 1 online resource (xx, 531 pages) : 112 illus., 100 illus. in color
- ISBN
- 9783319424996
- 9783319424989 (print ed.)
- Subjects (MeSH)
- Allergens - immunology
- Biomarkers - analysis
- Hypersensitivity - diagnosis
- Immunoglobulin E - immunology
- Molecular Diagnostic Techniques
- Sensitivity and Specificity
- Abstract
- This book, based on a recent German publication, offers an overview of basic data and recent developments in the groundbreaking field of molecular allergology. It comprehensively explores the origin and structure of single allergen molecules ("components") and their utility in improving the management of type I, IgE-mediated allergic reactions and disorders like allergic respiratory diseases, food allergies, and anaphylaxis. Highly specific testing, called component-resolved diagnostics, aims to identify and utilize single molecules. Over 200 single allergens from plant or animal sources have been applied to single or multiplex laboratory testing for the presence of allergen-specific IgE. This leap in assay sensitivity and specificity has led to three major advances in patient management: discrimination between primary allergic sensitization and complex cross-reactivity, recognition of IgE profiles for certain allergens and identification of patients most likely to benefit from allergen-specific immunotherapy. The book discusses in detail the benefits and limitations of this 21st century technology, and offers suggestions for the use of molecular allergology in routine clinical practice. It is a "must read" for physicians treating allergic patients as well as scientists interested in natural allergic molecules and their interactions with the human immune system.
- Contents
- Part I: Protein Families and Relationships -- 1. Introduction to Molecular Allergology: Protein Families, Databases, and Potential Benefits -- 2. Bet v 1 and its Homologs: Triggers of Tree-Pollen Allergy and Birch Pollen-Associated Cross-Reactions -- 3. The Concept of Pollen Panallergens: Profilins and Polcalcins -- 4. Stable Plant Food Allergens I: Lipid-Transfer Proteins -- 5. Stable Plant Food Allergens II: Storage Proteins -- 6. Cross-Reactive Carbohydrate Determinants: Diagnostic and Clinical Relevance -- Part II: Test Systems, Singleplex Analysis and Multiplex Analysis -- 7. Molecular Allergy Diagnostics Using IgE Singleplex Assays: Methodological and Practical Considerations -- 8. Spiking with Recombinant Individual Allergens for Improvement of Allergen Extracts -- 9. Molecular Allergy Diagnostics Using Multiplex Assays -- Part III: Marker Allergens -- 10. Marker Allergens and Panallergens in Tree and Grass Pollen Allergy -- 11. Marker Allergens of Weed Pollen: Basic Considerations and Diagnostic Benefits in Routine Clinical Practice -- 12. Molecular Diagnostics for Peanut Allergy -- 13. Molecular Diagnostics for Tree Nut Allergy -- 14. Molecular Diagnostics of Allergy to Fruits and Vegetables -- 15. Cow’s Milk and Hen’s Egg Allergy: What Do Molecular-Based Allergy Diagnostics Have to Offer? -- 16. Molecular and Extract-Based Diagnostics in Meat Allergy -- 17. Molecular Diagnostics in Food-Dependent Exercise-Induced Anaphylaxis -- 18. Benefits and Limitations of Recombinant Allergens in Diagnostics of Insect Venom Allergy -- 19. Molecular Diagnostics in Allergy to Mammals -- 20. Extract-Based and Molecular Diagnostics in Fish Allergy -- 21. Allergens and Molecular Diagnostics of Shellfish Allergy -- 22. Allergens, Diagnostics, and Therapeutic Aspects in House Dust Mite Allergy -- 23. Cockroach, Tick, Storage Mite, and Other Arthropod Allergies: Molecular Aspects -- 24. Mold Allergens and Their Importance in Molecular Allergy Diagnosis -- 25. Latex Allergens: Source of Sensitization and Single Allergens -- Part IV: Designer Allergens, Hypoallergens and Fusion Allergens -- 26. Recombinant Allergens in Specific Immunotherapy -- 27. Definition and Design of Hypoallergenic Foods.
- Format
- e-Book
- Location
- Online
Physiology, Psychoacoustics and Cognition in Normal and Impaired Hearing
https://libcat.nshealth.ca/en/permalink/provcat43938
Pim van Dijk, Deniz Baskent, Etienne Gaudrain, Emile de Kleine, Anita Wagner, Cris Lanting, editors.
--Cham:
SpringerOpen
, c2016.
- Available Online
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- Access
- Open access
- Location
- Online
The International Symposium on Hearing is a prestigious, triennial gathering where world-class scientists present and discuss the most recent advances in the field of human and animal hearing research. The 2015 edition will particularly focus on integrative approaches linking physiological, psychophysical and cognitive aspects of normal and impaired hearing. Like previous editions, the proceedings will contain about 50 chapters ranging from basic to applied research, and of interest to neurosci…
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- Other Authors
- van Dijk, Pim
- Baskent, Deniz
- Gaudrain, Etienne
- de Kleine, Emile
- Wagner, Anita
- Lanting, Cris
- Responsibility
- Pim van Dijk, Deniz Baskent, Etienne Gaudrain, Emile de Kleine, Anita Wagner, Cris Lanting, editors
- Place of Publication
- Cham
- Publisher
- SpringerOpen
- Date of Publication
- c2016
- Physical Description
- 1 online resource (xxix, 484 p.) : 138 illus., 92 illus. in color
- Series Vol.
- v. 894
- Series Title
- Advances in experimental medicine and biology
- ISBN
- 9783319254746
- 9783319254722 (Print ed.)
- 9783319254739 (Print ed.)
- 9783319797977 (Print ed.)
- ISSN
- 0065-2598
- Subjects (MeSH)
- Audiology
- Auditory Perception - physiology
- Hearing Disorders
- Hearing - physiology
- Psychoacoustics
- Specialty
- Audiology
- Abstract
- The International Symposium on Hearing is a prestigious, triennial gathering where world-class scientists present and discuss the most recent advances in the field of human and animal hearing research. The 2015 edition will particularly focus on integrative approaches linking physiological, psychophysical and cognitive aspects of normal and impaired hearing. Like previous editions, the proceedings will contain about 50 chapters ranging from basic to applied research, and of interest to neuroscientists, psychologists, audiologists, engineers, otolaryngologists, and artificial intelligent researchers.
- Access
- Open access
- Format
- e-Book
- Publication Type
- Congress
- Location
- Online
Sleep Medicine : A Comprehensive Guide to Its Development, Clinical Milestones, and Advances in Treatment
https://libcat.nshealth.ca/en/permalink/provcat39003
Sudhansu Chokroverty, Michel Billiard, editors.
(1st ed.)
--New York, NY:
Springer
, c2015.
- Available Online
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- Location
- Online
This comprehensive volume provides a balanced and easily readable account of the rise of modern sleep medicine, its history and developmental milestones. Authored by an international group of experts, the remarkable progress and fascinating evolution from rudimentary concepts of the ancient prehistoric and early classical periods to our contemporary knowledge are covered in detail. These examples and their relationship to modern therapies offer neurologists, psychiatrists, respiratory specialis…
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- View e-Book
- Other Authors
- Chokroverty, Sudhansu
- Billiard, Michel
- Responsibility
- Sudhansu Chokroverty, Michel Billiard, editors
- Edition
- 1st ed.
- Place of Publication
- New York, NY
- Publisher
- Springer
- Date of Publication
- c2015
- Physical Description
- 1 online resource (xix, 584 p. : 98 illus., 47 illus. in color)
- ISBN
- 9781493920891
- 9781493920884 (print ed.)
- Subjects (MeSH)
- Sleep Medicine Specialty
- Sleep Medicine Specialty - history
- Sleep Wake Disorders
- Sleep
- History of Medicine
- Abstract
- This comprehensive volume provides a balanced and easily readable account of the rise of modern sleep medicine, its history and developmental milestones. Authored by an international group of experts, the remarkable progress and fascinating evolution from rudimentary concepts of the ancient prehistoric and early classical periods to our contemporary knowledge are covered in detail. These examples and their relationship to modern therapies offer neurologists, psychiatrists, respiratory specialists, clinicians, researchers and those interested in sleep medicine an important perspective to the origins of current practice.
- Contents
- Introduction -- Part I. Evolution of Sleep Medicine by Historical Periods -- Sleep in Ancient Egypt -- Sleep Medicine in the Arab Islamic Civilization -- Sleep Medicine in Ancient and Traditional India -- Sleep Medicine in Ancient and Traditional China -- Sleep in the Biblical Period -- Sleep in the New Testament -- The Greco-Roman Period -- The Aztec, Maya, and Inca Civilizations -- Part II. Sleep Medicine from the Medieval Period to the 19th Century -- Sleep Medicine in the Middle Ages and the Renaissance -- Sleep in the 17th and 18th Centuries -- Part III. The Early Evolution of Modern Sleep Medicine -- The Evolution of Sleep Medicine in the 19th and the Early 20th Century -- The History of Polysomnography: Tool of Scientific Discovery -- Part IV. Sleep Medicine Societies, Professional Societies, and Journals -- A History Behind the Development of Sleep Medicine and Sleep Societies -- Development of Sleep Medicine in Europe -- Evolution of Sleep Medicine in Japan -- History of Japanese Clinical Sleep Medicine -- Sleep Medicine around the World (Beyond North American and European Continents) -- Part V. Sleep Disorders in Historic Diseases -- Cholera -- Encephalities Lethargica -- African Sleeping Sickness -- Sleep and HIV Disease -- Part VI. Historical Milestones of Individual Sleep Disorders -- Evolution of the Classification of Sleep Disorders -- History of Epidemiological Research in Sleep Medicine -- The Insomnias: Historical Evolution -- Part VII. Neurological Sleep Disorders -- Narcolepsy-Cataplexy Syndrome and Symptomatic Hypersomnia -- Idiopathic Hypersomnia -- Kleine-Levin Syndrome -- Movement Disorders in Sleep -- History of Restless Legs Syndrome, Recently Named Willis-Ekbom Disease -- Sleep and Stroke -- Sleep in Neurodegenerative Diseases -- Sleep, Cognitive Dysfunction, and Dementia -- Fatal Familial Insomnia and Agrypnia Excitata: Insights into Human Prion Disease Genetics and the Anatomo-Physiology of Wake and Sleep Behaviours -- Epilepsy and Sleep -- Sleep Disorders after Traumatic Brain Injury: Milestones in Perspective -- Headache Syndromes and Sleep -- Part VIII. Psychiatric and Psychological Sleep Disorders -- Depression -- Schizophrenia and Psychosis -- Bipolar Disorder -- Part IX. Respiratory Diseases -- A Short History of Obstructive Sleep Apnea Syndrome -- Upper Airway Resistance Syndrome: A Short History -- Restrictive and Obstructive Lung Diseases and Sleep Disorders -- NREM Arousal Parasomnias -- REM Sleep Behavior Disorder -- Chronobiology and Sleep -- Part X. Medical Disorders and Sleep -- Cardiovascular Disease and Sleep Dysfunction -- Nonrestorative Sleep, Musculoskeletal Pain, Fatigue in Rheumatic Disorders and Allied Syndromes: A Historical Perspective -- Sleep and Pain: Milestones and Advances from Research -- Endocrine-Metabolic Disorders and Sleep Medicine -- The Gut and Sleep -- Impotence and Erectile Problems in Sleep Medicine -- Women's Health and Sleep Disorders -- Part XI. Miscellaneous Important Aspects -- The Emergence of Pediatric Sleep Medicine -- Sleep Disorders, Cognition, Accidents, and Performance -- Sleep Deprivation: Societal Impact and Long Term Consequences -- Sleep Models -- Part XII. Evolution of Treatment and Investigative Approaches in Sleep Medicine -- A History of Non-Pharmacological Treatments for Insomnia -- The Pharmacological Treatment of Sleep Disorders -- Psychological Treatment of Insomnia: The Evolution of Behavior Therapy and Cognitive Behavior Therapy -- Modafinil: Development and Use of the Compound -- Phylogeny in Sleep Medicine -- Gamma-Hyroxybutyrate (Sodium Oxybate): From the Initial Synthesis to the Treatment of Narcolepsy Cataplexy and Beyond -- Development and Impact of Brain Imaging Techniques.
- Format
- e-Book
- Location
- Online
